#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O89019 uniprotkb:P11499 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282363|imex:IM-16529-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:99402757C153CF20|rigid:pz80PWjdbkNn+gJv+VbH5AK/BYE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O89019 uniprotkb:Q8BP00 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282363|imex:IM-16529-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:99402757C153CF20|rigid:pz80PWjdbkNn+gJv+VbH5AK/BYE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O89019 uniprotkb:P63017 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282363|imex:IM-16529-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:99402757C153CF20|rigid:pz80PWjdbkNn+gJv+VbH5AK/BYE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O89019 uniprotkb:Q91ZR4 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-4282339|uniprotkb:Q3U498|uniprotkb:Q9D685|ensembl:ENSMUSP00000017549 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:nek8_mouse(display_long)|uniprotkb:Nek8(gene name)|psi-mi:Nek8(display_short)|uniprotkb:Jck(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282363|imex:IM-16529-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) ensembl:ENSMUSG00000017405(gene)|ensembl:ENSMUST00000017549(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044120|refseq:NP_543125.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:aaLad1nm9yceDiO9kCqZGghKWRc10090 intact-crc:99402757C153CF20|rigid:pz80PWjdbkNn+gJv+VbH5AK/BYE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O89019 uniprotkb:P38647 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282363|imex:IM-16529-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:99402757C153CF20|rigid:pz80PWjdbkNn+gJv+VbH5AK/BYE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O89019 uniprotkb:P20029 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282363|imex:IM-16529-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:99402757C153CF20|rigid:pz80PWjdbkNn+gJv+VbH5AK/BYE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q3TWM5 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4282474|ensembl:ENSMUSP00000105986 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:q3twm5_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_001277941.1|refseq:NP_058598.1|ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000110357(transcript)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:nyTlcuSXoBcbvrTaVBI1Su4wG0E10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P07901 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:O88533 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4282417|ensembl:ENSMUSP00000068525|ensembl:ENSMUSP00000105286|ensembl:ENSMUSP00000136467 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ddc_mouse(display_long)|uniprotkb:Ddc(gene name)|psi-mi:Ddc(display_short)|uniprotkb:DOPA decarboxylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUST00000109659(transcript)|ensembl:ENSMUST00000178704(transcript)|go:"GO:0004058"(aromatic-L-amino-acid decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0016597"(amino acid binding)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030424"(axon)|interpro:IPR010977(Aromatic-L-amino-acid decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:O88533|reactome:R-MMU-209905|reactome:R-MMU-209931|go:"GO:0033076"(isoquinoline alkaloid metabolic process)|go:"GO:0035690"|go:"GO:0036467"(5-hydroxy-L-tryptophan decarboxylase activity)|go:"GO:0036468"(L-dopa decarboxylase activity)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046684"(response to pyrethroid)|go:"GO:0052314"(phytoalexin metabolic process)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|ensembl:ENSMUSG00000020182(gene)|ensembl:ENSMUST00000066237(transcript)|refseq:NP_001177377.1|refseq:NP_057881.1|refseq:XP_006514550.1|refseq:XP_006514551.1|refseq:XP_006514552.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:rPipOOdkRJoCVaSpjsJ9jQvKgNg10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q71LX8 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-2657945 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:A1E2B8 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4282145 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:a1e2b8_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) go:"GO:0005524"(ATP binding)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:ZWP3SAChvtexmuiM2xOxCL9ud0U10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:D6RIK9 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4282437|ensembl:ENSMUSP00000118230 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:d6rik9_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000139113(transcript)|go:"GO:0001736"(establishment of planar polarity)|interpro:IPR031136|interpro:IPR031139 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:tFhs49DDpjGoC5If+cAPHb2crc010090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P20029 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P59240 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P63017 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P62983 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4282373|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P49664|uniprotkb:P62991|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D2W3|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|ensembl:ENSMUSP00000099908|ensembl:ENSMUSP00000099909 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:rs27a_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-5689901|reactome:R-MMU-5693565|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6783310|reactome:R-MMU-6791226|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804760|reactome:R-MMU-6807004|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-5689877|reactome:R-MMU-69231|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-69601|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-75815|reactome:R-MMU-8849469|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8863795|reactome:R-MMU-8866652|reactome:R-MMU-8866654|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948747|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-901032|reactome:R-MMU-9010553|reactome:R-MMU-9013507|reactome:R-MMU-9020702|reactome:R-MMU-9033241|reactome:R-MMU-912631|reactome:R-MMU-917729|reactome:R-MMU-917937|reactome:R-MMU-936440|reactome:R-MMU-936964|reactome:R-MMU-937039|reactome:R-MMU-937041|reactome:R-MMU-937042|reactome:R-MMU-8932339|reactome:R-MMU-937072|reactome:R-MMU-9645460|reactome:R-MMU-9648002|reactome:R-MMU-9664873|reactome:R-MMU-9705462|reactome:R-MMU-9706369|reactome:R-MMU-9708530|reactome:R-MMU-975144|reactome:R-MMU-975163|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-983168|reactome:R-MMU-9646399|ensembl:ENSMUSG00000020460(gene)|ensembl:ENSMUST00000102844(transcript)|ensembl:ENSMUST00000102845(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|reactome:R-MMU-110320|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1253288|reactome:R-MMU-1295596|reactome:R-MMU-1358803|reactome:R-MMU-156827|reactome:R-MMU-168638|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|reactome:R-MMU-174048|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-179409|reactome:R-MMU-1799339|reactome:R-MMU-182971|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-201681|reactome:R-MMU-202424|reactome:R-MMU-205043|interpro:IPR038582|rcsb pdb:5GVI|reactome:R-MMU-209543|rcsb pdb:5XIS|rcsb pdb:5XIT|rcsb pdb:5XIU|reactome:R-MMU-209560|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-2173788|reactome:R-MMU-2173791|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-2467813|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2565942|reactome:R-MMU-2672351|reactome:R-MMU-2871837|reactome:R-MMU-3134975|reactome:R-MMU-349425|reactome:R-MMU-3769402|reactome:R-MMU-382556|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-2122948|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-4641263|reactome:R-MMU-532668|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5675221|reactome:R-MMU-5675482|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-5685942|reactome:R-MMU-5687128|reactome:R-MMU-5689603|refseq:NP_001029037.1|refseq:NP_077239.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:AkJxTgRFL5RT5jWk5i3y4zX5tfA10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P38647 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:B2RQC6 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-3043834|ensembl:ENSMUSP00000013773|uniprotkb:B7ZN27 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:pyr1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282416|imex:IM-16529-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000013629(gene)|ensembl:ENSMUST00000013773(transcript)|go:"GO:0002134"(UTP binding)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0001889"(liver development)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|go:"GO:0019899"(enzyme binding)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:B2RQC6|reactome:R-MMU-500753|refseq:NP_076014.1|refseq:NP_001276451.1|dip:DIP-61412N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:t+qQw7me78vEm/Y4VBBhS8fmCsY10090 intact-crc:4D7B2E7402384DE8|rigid:Bt0mwkrvbKkduQJ9qJVRQkrHsDA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6A078 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63017 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P62204 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P20029 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A5JUZ1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280663 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1G4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282128 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u1g4_mouse(display_long)|uniprotkb:Exoc1(gene name)|psi-mi:Exoc1(display_short)|uniprotkb:Sec3l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|interpro:IPR019160|interpro:IPR028258 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:K9P9YJ1MVDPgVMEvI6DXMm18qOI10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P38647 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q80VF8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282502 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q80vf8_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short)|uniprotkb:Cad-pending(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR036901|interpro:IPR032466|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0016812"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides")|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:zZbrI7EBG3zA1CcwaTo+X4Byi6810090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q7TN13 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282197 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q7tn13_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036480|interpro:IPR036897|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR017926|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029062|interpro:IPR035686 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:gEKS8aEgMRHW9j5uSQJG0RQT9mE10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P80317 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772389 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tcpz_mouse(display_long)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Cct6a(gene name)|psi-mi:Cct6a(display_short)|uniprotkb:Cct6(gene name synonym)|uniprotkb:Cctz(gene name synonym)|uniprotkb:Cctz1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033968.1|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|mint:P80317|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|reactome:R-MMU-390471|reactome:R-MMU-6814122|reactome:R-MMU-9013418 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:E8vqHRMvDBqKtAu5/6UPh1mSYLw10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P28656 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-645055|uniprotkb:Q3UL14|ensembl:ENSMUSP00000070068|ensembl:ENSMUSP00000151750|ensembl:ENSMUSP00000151972 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:np1l1_mouse(display_long)|uniprotkb:NAP-1-related protein(gene name synonym)|uniprotkb:Brain protein DN38(gene name synonym)|uniprotkb:Nap1l1(gene name)|psi-mi:Nap1l1(display_short)|uniprotkb:Nrp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_056596.1|ensembl:ENSMUSG00000058799(gene)|ensembl:ENSMUST00000065917(transcript)|ensembl:ENSMUST00000217908(transcript)|ensembl:ENSMUST00000218828(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019900"(kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P28656 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AW+O1Tr5ZJ+2UVKVdK/5fqXesSs10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P80317 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772389 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tcpz_mouse(display_long)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Cct6a(gene name)|psi-mi:Cct6a(display_short)|uniprotkb:Cct6(gene name synonym)|uniprotkb:Cctz(gene name synonym)|uniprotkb:Cctz1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033968.1|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|mint:P80317|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|reactome:R-MMU-390471|reactome:R-MMU-6814122|reactome:R-MMU-9013418 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:E8vqHRMvDBqKtAu5/6UPh1mSYLw10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9Z0X1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773597|intact:EBI-4282542|uniprotkb:Q1L6K5|ensembl:ENSMUSP00000041104 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:aifm1_mouse(display_long)|uniprotkb:Programmed cell death protein 8(gene name synonym)|uniprotkb:Aifm1(gene name)|psi-mi:Aifm1(display_short)|uniprotkb:Aif(gene name synonym)|uniprotkb:Pdcd8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001277293.1|refseq:NP_036149.1|ensembl:ENSMUSG00000036932(gene)|ensembl:ENSMUST00000037349(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004174"(electron-transferring-flavoprotein dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:Q9Z0X1|rcsb pdb:1GV4|rcsb pdb:3GD3|rcsb pdb:3GD4|rcsb pdb:5MIU|rcsb pdb:5MIV psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:c0oYNXW1lpmieqgWc4TZra/RJNk10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P80318 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772361|ensembl:ENSMUSP00000001452 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A1E2B8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282145 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a1e2b8_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0005524"(ATP binding)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ZWP3SAChvtexmuiM2xOxCL9ud0U10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P33610 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6P9L1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282173 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6p9l1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR006680(Amidohydrolase 1)|interpro:IPR036897|interpro:IPR036914|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR032466|go:"GO:0005524"(ATP binding)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016812"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides")|go:"GO:0016874"(ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:hjrxaxAVU5nojAo6/iZZnfCbv0s10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TIR3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282521|uniprotkb:Q3TEY3|uniprotkb:Q99JW0|uniprotkb:Q9ERR6|ensembl:ENSMUSP00000026558 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ric8a_mouse(display_long)|uniprotkb:Ric8a(gene name)|psi-mi:Ric8a(display_short)|uniprotkb:Ric8(gene name synonym)|uniprotkb:Protein Ric-8A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000025485(gene)|ensembl:ENSMUST00000026558(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001944"(vasculature development)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0070586"(cell-cell adhesion involved in gastrulation)|go:"GO:0071711"(basement membrane organization)|interpro:IPR008376(Synembryn)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019318|refseq:NP_444424.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:tYG6cM1ifCtx+TeAE6h4Hmti80M10090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TIH7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282571 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tih7_mouse(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:Cdc45l(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282570|imex:IM-16529-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR003874(CDC45-like protein)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2018/04/06 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:rvl6/dsl7u+EBRfcnkC7egoGyO010090 intact-crc:170C682F9199177C|rigid:GlVfMW/8R0tHYE5MLzcQvdGi4D4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:E9Q557 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-688046|ensembl:ENSMUSP00000115062 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)" figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P52480 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-647785|uniprotkb:Q3TBV8|uniprotkb:Q3TBW5|uniprotkb:Q3TC59|uniprotkb:Q3U1X3|uniprotkb:Q3U5P6|uniprotkb:Q4VC20|uniprotkb:Q64484|uniprotkb:Q91YI8|uniprotkb:Q9CWB1|ensembl:ENSMUSP00000034834 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:kpym_mouse(display_long)|uniprotkb:Pkm(gene name)|psi-mi:Pkm(display_short)|uniprotkb:Pk3(gene name synonym)|uniprotkb:Pkm2(gene name synonym)|uniprotkb:Pykm(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_035229.2|refseq:XP_006510918.1|refseq:NP_001240812.1|refseq:XP_011240975.1|dip:DIP-40536N|ensembl:ENSMUSG00000032294(gene)|ensembl:ENSMUST00000034834(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001889"(liver development)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043531"(ADP binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1902912"(pyruvate kinase complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P52480|reactome:R-MMU-6798695|reactome:R-MMU-70171 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:SWQx3aPATcnlExhyy8afjcrB+xo10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P48678 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-299212|ensembl:ENSMUSP00000029699|uniprotkb:P11516|uniprotkb:P97859|uniprotkb:Q3TIH0|uniprotkb:Q3TTS8|uniprotkb:Q3UCA0|uniprotkb:Q3UCJ8|uniprotkb:Q91WF2|uniprotkb:Q9DC21|uniprotkb:B3RH23|uniprotkb:B3RH24|uniprotkb:Q3U733|uniprotkb:Q3U7I5|uniprotkb:Q3UCU3 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:lmna_mouse(display_long)|uniprotkb:Lmna(gene name)|psi-mi:Lmna(display_short)|uniprotkb:Lmn1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|ensembl:ENSMUSG00000028063(gene)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|ensembl:ENSMUST00000029699(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P48678|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|rcsb pdb:1UFG|reactome:R-MMU-352238|reactome:R-MMU-4419969|refseq:NP_001002011.2|refseq:NP_001104572.1|refseq:NP_062263.1|refseq:XP_006501136.1|dip:DIP-31384N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:bJz9o/dZoD9E4CRP1FLYihybpwA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P59913 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282915|ensembl:ENSMUSP00000059261 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:pcmd1_mouse(display_long)|uniprotkb:Pcmtd1(gene name)|psi-mi:Pcmtd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_898849.1|ensembl:ENSMUSG00000051285(gene)|ensembl:ENSMUST00000061280(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:HCK1zY5gjRef1W5wg+vWdKvmt9g10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P60761 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-771601|uniprotkb:Q3TYH4|uniprotkb:B2RRN7|ensembl:ENSMUSP00000070113 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:neug_mouse(display_long)|uniprotkb:RC3(gene name synonym)|uniprotkb:Nrgn(gene name)|psi-mi:Nrgn(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_071312.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0021537"(telencephalon development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR000048(IQ calmodulin-binding region)|rcsb pdb:4E50|ensembl:ENSMUSG00000053310(gene)|ensembl:ENSMUST00000065668(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008306"(associative learning)|go:"GO:0012510"(trans-Golgi network transport vesicle membrane) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:a++S4V0kObXutTb8DwokHhJfL3k10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q8K0Z5 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282752 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q8k0z5_mouse(display_long)|uniprotkb:Tpm3(gene name)|psi-mi:Tpm3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000533(Tropomyosin)|refseq:NP_071709.3|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:M5MEaLBxViGgnGUPrdZk9cL6wFg10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P97315 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-2255521|ensembl:ENSMUSP00000027677|ensembl:ENSMUSP00000095169 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:csrp1_mouse(display_long)|uniprotkb:Crp1(gene name synonym)|uniprotkb:Csrp(gene name synonym)|uniprotkb:Csrp1(gene name)|psi-mi:Csrp1(display_short)|uniprotkb:Cysteine-rich protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_031817.1|ensembl:ENSMUSG00000026421(gene)|ensembl:ENSMUST00000027677(transcript)|ensembl:ENSMUST00000097561(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P97315 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:fe2AfDN/ZZntzGCJ8jH9WhyZtdQ10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P70296 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1634763|uniprotkb:Q9D8G9|uniprotkb:Q9JJ58|ensembl:ENSMUSP00000048425 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:pebp1_mouse(display_long)|uniprotkb:Pebp1(gene name)|psi-mi:Pebp1(display_short)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pebp(gene name synonym)|uniprotkb:HCNPpp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_061346.2|ensembl:ENSMUSG00000032959(gene)|ensembl:ENSMUST00000036951(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043679"(axon terminus)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045177"(apical part of cell)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060409"(positive regulation of acetylcholine metabolic process)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P70296|rcsb pdb:6ENS|reactome:R-MMU-5674135|reactome:R-MMU-5675221 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:vhkkuZ49z3Vuw7O4bdlc/5WxlKk10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P29391 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-309285|uniprotkb:Q8WUQ8 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:fril1_mouse(display_long)|uniprotkb:Ftl1(gene name)|psi-mi:Ftl1(display_short)|uniprotkb:Ftl(gene name synonym)|uniprotkb:Ftl-1(gene name synonym)|uniprotkb:Ferritin L subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR009040(Ferritin-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR014034(Ferritin, conserved site)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:1H96|rcsb pdb:1LB3|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0071682"(endocytic vesicle lumen) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:9LMyVftFjQVCxzUakUZ7W3L5Pig10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P52503 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282864|uniprotkb:Q5M9J7|ensembl:ENSMUSP00000022097 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:ndus6_mouse(display_long)|uniprotkb:Ndufs6(gene name)|psi-mi:Ndufs6(display_short)|uniprotkb:Ip13(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_035018.1|ensembl:ENSMUSG00000021606(gene)|ensembl:ENSMUST00000022097(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0061458"(reproductive system development)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0072359"(circulatory system development)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:UiOXov1vYsPtTiFWx2h+1WidgE410090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q02819 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1634689|uniprotkb:Q3TU42|uniprotkb:Q9CWA1|uniprotkb:Q9D8J4|uniprotkb:Q9DBL3|ensembl:ENSMUSP00000147383 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:nucb1_mouse(display_long)|uniprotkb:Nucb1(gene name)|psi-mi:Nucb1(display_short)|uniprotkb:Nuc(gene name synonym)|uniprotkb:Nucb(gene name synonym)|uniprotkb:CALNUC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001157134.1|refseq:NP_032775.1|refseq:XP_017177513.1|refseq:XP_006540759.1|ensembl:ENSMUSG00000030824(gene)|ensembl:ENSMUST00000211765(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02819|reactome:R-MMU-381426|reactome:R-MMU-8957275|go:"GO:0005794"(Golgi apparatus) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:/Iqiy8TmMklf3hIyYKPce37SBP010090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P17751 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-444877|uniprotkb:Q3TJH2|uniprotkb:Q3UC04|uniprotkb:Q3UKG9|uniprotkb:Q64513|uniprotkb:Q9CVF9|uniprotkb:Q9CWE7|ensembl:ENSMUSP00000130858 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:tpis_mouse(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Tpi(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_033441.2|ensembl:ENSMUSG00000023456(gene)|ensembl:ENSMUST00000172132(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P17751|reactome:R-MMU-70171|reactome:R-MMU-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:1+uasFpsjnuX50Ti23iaIawdp7k10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q71LX8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-2657945 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3UM23 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4281076 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:O35129 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-445002|uniprotkb:O89075|uniprotkb:Q61336|ensembl:ENSMUSP00000004375 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:phb2_mouse(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bap(gene name synonym)|uniprotkb:Bcap37(gene name synonym)|uniprotkb:Rea(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_031557.2|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:O35129|reactome:R-MMU-8949664|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|ensembl:ENSMUSG00000004264(gene)|ensembl:ENSMUST00000004375(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0016477"(cell migration) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:h4pib54mBeQgOKCe/hib58LM26w10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3UFT0 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282763 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3uft0_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0016459"(myosin complex)|interpro:IPR002928(Myosin tail) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:HrPqwIemcFCEqPIUP1s29fCSXns10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q04447 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1634233|uniprotkb:Q3KQP4|uniprotkb:Q3TKI3|uniprotkb:Q3U5P5|uniprotkb:Q3UF71|uniprotkb:Q9CXK6|ensembl:ENSMUSP00000001304 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:kcrb_mouse(display_long)|uniprotkb:Ckb(gene name)|psi-mi:Ckb(display_short)|uniprotkb:Ckbb(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:B-CK(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_067248.1|ensembl:ENSMUSG00000001270(gene)|ensembl:ENSMUST00000001304(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q04447|reactome:R-MMU-71288|reactome:R-MMU-9696264 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:7r2Owq3p9g124vCs/sG4m8aScuU10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P20357 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-397863|ensembl:ENSMUSP00000109646|uniprotkb:E9QLE1 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:mtap2_mouse(display_long)|uniprotkb:Map2(gene name)|psi-mi:Map2(display_short)|uniprotkb:Mtap2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000015222(gene)|ensembl:ENSMUST00000114013(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097442"(CA3 pyramidal cell dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR030797|mint:P20357|refseq:XP_006495817.1|refseq:NP_001297563.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:iZ9zGAAalOtaFcgpzAQ80o+lCj010090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q148V8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282953|uniprotkb:Q8BZF6|uniprotkb:Q8CI79|uniprotkb:Q8R5C2|uniprotkb:Q8R5D0|ensembl:ENSMUSP00000059839|ensembl:ENSMUSP00000126453 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:fa83h_mouse(display_long)|uniprotkb:Fam83h(gene name)|psi-mi:Fam83h(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001161725.1|refseq:NP_598848.2|refseq:XP_006520300.1|ensembl:ENSMUSG00000046761(gene)|ensembl:ENSMUST00000060807(transcript)|ensembl:ENSMUST00000170153(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:1990254"(keratin filament binding)|interpro:IPR012461(Protein of unknown function DUF1669)|interpro:IPR041996|mint:Q148V8|refseq:XP_006520299.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:3NLWjiNTj+wG44iNYtr/1ghJDu410090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P56480 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q05CR7 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282670 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q05cr7_mouse(display_long)|uniprotkb:Vcan(gene name)|psi-mi:Vcan(display_short)|uniprotkb:Cspg2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036179|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:AkqY/F97Cd0fqtPr0l+agJ71xWI10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P62897 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-2308573|uniprotkb:P00009|uniprotkb:Q8C2S2|ensembl:ENSMUSP00000072829|ensembl:ENSMUSP00000124523 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:cyc_mouse(display_long)|uniprotkb:Cycs(gene name)|psi-mi:Cycs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_031834.1|ensembl:ENSMUSG00000058927(gene)|ensembl:ENSMUSG00000063694(gene)|ensembl:ENSMUST00000073080(transcript)|ensembl:ENSMUST00000161401(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009055"(electron transfer activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|mint:P62897|reactome:R-MMU-111457|reactome:R-MMU-111458|reactome:R-MMU-111459|reactome:R-MMU-2151201|reactome:R-MMU-3299685|reactome:R-MMU-5620971|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9627069|reactome:R-MMU-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:vpo8RqJEpxq8eWPVl7eJfjlhUb010090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A2ARP8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282656|ensembl:ENSMUSP00000092223 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a2arp8_mouse(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036866|ensembl:ENSMUSG00000027254(gene)|ensembl:ENSMUST00000094639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|interpro:IPR015656(MAP1A)|interpro:IPR026074|refseq:NP_115769.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:hxR08JZchvZqd2J86dz0xTuQARA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A5JUZ1 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4280663 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q60598 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-397955|intact:EBI-4281621|uniprotkb:Q3UGC2|ensembl:ENSMUSP00000099368 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:src8_mouse(display_long)|uniprotkb:Cttn(gene name)|psi-mi:Cttn(display_short)|uniprotkb:Ems1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_031829.2|ensembl:ENSMUSG00000031078(gene)|ensembl:ENSMUST00000103079(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030054"(cell junction)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|interpro:IPR036028|mint:Q60598|rcsb pdb:2F9X|rcsb pdb:3ULR|rcsb pdb:5NV1|rcsb pdb:5NVJ|rcsb pdb:5NXJ|reactome:R-MMU-8856828|dip:DIP-31562N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:4hLyMrquWdlJnIX2pHuXqYtQgkE10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P12710 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282834|ensembl:ENSMUSP00000064655 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:fabpl_mouse(display_long)|uniprotkb:Fabp1(gene name)|psi-mi:Fabp1(display_short)|uniprotkb:Fabpl(gene name synonym)|uniprotkb:14 kDa selenium-binding protein(gene name synonym)|uniprotkb:Fatty acid-binding protein 1(gene name synonym)|uniprotkb:Liver-type fatty acid-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032052"(bile acid binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036094"(small molecule binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051345"(positive regulation of hydrolase activity)|ensembl:ENSMUSG00000054422(gene)|ensembl:ENSMUST00000067492(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|refseq:NP_059095.1|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR012674(Calycin)|interpro:IPR031259|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR031276|mint:P12710|reactome:R-MMU-163560|reactome:R-MMU-189483|reactome:R-MMU-400206|reactome:R-MMU-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:cB3Av7VZvtWsvsnH2gTjx5Kwc/U10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A1Z2X7 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282998 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a1z2x7_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036028|interpro:IPR001452(Src homology-3)|interpro:IPR039687|interpro:IPR030642 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:JO20RP3ZXn3hNLjsYxjncxhpS/Y10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q03265 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q7TSJ2 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-774081|uniprotkb:O55129|uniprotkb:O70586|uniprotkb:O70587|uniprotkb:Q78DV4|uniprotkb:Q78DV5|intact:EBI-911047|ensembl:ENSMUSP00000064787|ensembl:ENSMUSP00000146585 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:map6_mouse(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001036820.2|refseq:NP_001041632.1|refseq:NP_034967.2|ensembl:ENSMUSG00000055407(gene)|ensembl:ENSMUST00000068973(transcript)|ensembl:ENSMUST00000207883(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR007882(STOP)|mint:Q7TSJ2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:NfrleOOHFaMul1xiYAgILTgLzWg10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P09411 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1634776|uniprotkb:Q3TPE6|uniprotkb:Q3UKV8|uniprotkb:Q5XJE7|ensembl:ENSMUSP00000080302 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:pgk1_mouse(display_long)|uniprotkb:Pgk1(gene name)|psi-mi:Pgk1(display_short)|uniprotkb:Pgk-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_032854.2|dip:DIP-51710N|ensembl:ENSMUSG00000062070(gene)|ensembl:ENSMUST00000081593(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P09411|rcsb pdb:4O3F|reactome:R-MMU-70171|reactome:R-MMU-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:388hPtU1n0xYbopG53ZWslYTzuk10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q91VW3 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4283066|ensembl:ENSMUSP00000030651 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:sh3l3_mouse(display_long)|uniprotkb:Sh3bgrl3(gene name)|psi-mi:Sh3bgrl3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_542126.1|rcsb pdb:1T1V|ensembl:ENSMUSG00000028843(gene)|ensembl:ENSMUST00000030651(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016604"(nuclear body)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|mint:Q91VW3|rcsb pdb:1J0F psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:LUXHvmkv+8TRRAoMq7vHwv+HjO010090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P50543 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4283032|uniprotkb:Q545S1|ensembl:ENSMUSP00000029515 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:s10ab_mouse(display_long)|uniprotkb:S100a11(gene name)|psi-mi:S100a11(display_short)|uniprotkb:S100c(gene name synonym)|uniprotkb:Calgizzarin(gene name synonym)|uniprotkb:Endothelial monocyte-activating polypeptide(gene name synonym)|uniprotkb:Protein S100-C(gene name synonym)|uniprotkb:S100 calcium-binding protein A11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_058020.1|ensembl:ENSMUSG00000027907(gene)|ensembl:ENSMUST00000029515(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028482|mint:P50543|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:MH8d02F0yB0bkvZNCJA+XyP7v7c10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q86YZ3 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A2ANT9 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282906|ensembl:ENSMUSP00000103376 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a2ant9_mouse(display_long)|uniprotkb:Anks6(gene name)|psi-mi:Anks6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000066191(gene)|ensembl:ENSMUST00000107747(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:VCAEax0DjFbEAp/ls3NRE8avZO410090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q8C845 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282851|ensembl:ENSMUSP00000044502 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q8c845_mouse(display_long)|uniprotkb:Efhd2(gene name)|psi-mi:Efhd2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_080270.2|ensembl:ENSMUSG00000040659(gene)|ensembl:ENSMUST00000036854(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040365 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:v3A9/LbdCzJxDCRky03TZA8gSmw10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P58771 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-298478|uniprotkb:P02558|uniprotkb:P19354|uniprotkb:P46902|uniprotkb:P99034|ensembl:ENSMUSP00000109315 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:tpm1_mouse(display_long)|uniprotkb:Tpm-1(gene name synonym)|uniprotkb:Tpma(gene name synonym)|uniprotkb:Tpm1(gene name)|psi-mi:Tpm1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000032366(gene)|ensembl:ENSMUST00000113685(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051693"(actin filament capping)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000533(Tropomyosin)|mint:P58771|rcsb pdb:7NEP|reactome:R-MMU-390522|reactome:R-MMU-445355|go:"GO:0003779"(actin binding)|refseq:NP_001157720.1|refseq:NP_077745.2|dip:DIP-300N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:d/imATvus0XZvr7i//2MtbXZ7Pw10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q05CS7 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282879 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q05cs7_mouse(display_long)|uniprotkb:Eea1(gene name)|psi-mi:Eea1(display_short)|uniprotkb:ZFYVE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:oD3h0BDJ+ezc4+5Pvwd9Yjtg3vw10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P27546 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-2526714|uniprotkb:Q05BJ2|uniprotkb:Q3UIS2|uniprotkb:Q3UUH5|uniprotkb:Q3UY36|uniprotkb:Q7TPC6|uniprotkb:Q7TPD4|uniprotkb:Q80YQ5|uniprotkb:Q8CFP5|ensembl:ENSMUSP00000035055 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:map4_mouse(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)|uniprotkb:Mtap4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001192259.1|refseq:NP_001192261.1|refseq:NP_032659.2|ensembl:ENSMUSG00000032479(gene)|ensembl:ENSMUST00000035055(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27546|go:"GO:0043005"(neuron projection)|refseq:NP_001298092.1|refseq:NP_001298093.1|refseq:XP_017168653.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:DVblnhNfUaxX6rpvxn660Pq09L410090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q4FK74 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282787 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q4fk74_mouse(display_long)|uniprotkb:Atp5d(gene name)|psi-mi:Atp5d(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036771|interpro:IPR036794|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|refseq:NP_079589.2|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|refseq:XP_017169541.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:OnHrRT8QSvjfiVkcCbJDVWPLD8I10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P08228 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1635090|ensembl:ENSMUSP00000023707 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:sodc_mouse(display_long)|uniprotkb:Sod1(gene name)|psi-mi:Sod1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_035564.1|dip:DIP-48691N|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036423|mint:P08228|rcsb pdb:3GTT|rcsb pdb:3GTV|rcsb pdb:3LTV|reactome:R-MMU-114608|reactome:R-MMU-3299685|ensembl:ENSMUSG00000022982(gene)|ensembl:ENSMUST00000023707(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019899"(enzyme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:BeyfJ/d3Dn+3pu1Nkl8n/x4Qriw10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P10630 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1634890|uniprotkb:Q61513|uniprotkb:Q61514|ensembl:ENSMUSP00000023599 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:if4a2_mouse(display_long)|uniprotkb:Eif4a2(gene name)|psi-mi:Eif4a2(display_short)|uniprotkb:Ddx2b(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001116509.1|refseq:NP_001116510.1|refseq:NP_038534.2|refseq:NP_001334108.1|ensembl:ENSMUSG00000022884(gene)|ensembl:ENSMUST00000023599(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P10630|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:m9i/jWfsbU+6kQvj1h06x31+awg10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A8IK50 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4283054|ensembl:ENSMUSP00000121079 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a8ik50_mouse(display_long)|uniprotkb:Pcp2(gene name)|psi-mi:Pcp2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001123275.1|ensembl:ENSMUSG00000004630(gene)|ensembl:ENSMUST00000136105(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR042168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:fdd1BzCKjo/dxxTneRR8LfBG8UI10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q543N3 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282726 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q543n3_mouse(display_long)|uniprotkb:Lasp1(gene name)|psi-mi:Lasp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036028|go:"GO:0003779"(actin binding)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0046872"(metal ion binding)|refseq:NP_034818.1|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:XP_006532404.1|interpro:IPR035630 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:bjQIqialH4yN2opuXwGU1XG2q8g10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P05213 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A5JUZ1 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4280663 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q8VCQ8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282687|ensembl:ENSMUSP00000110673 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q8vcq8_mouse(display_long)|uniprotkb:Cald1(gene name)|psi-mi:Cald1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000029761(gene)|ensembl:ENSMUST00000115021(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030478"(actin cap)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q8VCQ8|refseq:NP_663550.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:gFJMtF7/sH5eiLlx5zT2gpt4XVo10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q6GQX6 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282889|ensembl:ENSMUSP00000155271 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:anks6_mouse(display_long)|uniprotkb:Anks6(gene name)|psi-mi:Anks6(display_short)|uniprotkb:Gm635(gene name synonym)|uniprotkb:Samd6(gene name synonym)|uniprotkb:SamCystin(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:XP_006538395.1|ensembl:ENSMUSG00000066191(gene)|ensembl:ENSMUST00000229609(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0042802"(identical protein binding)|go:"GO:0097543"(ciliary inversin compartment)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:wBL0DqvWJmVjFAZVSh4fUdBRaTc10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q62418 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1550322|uniprotkb:Q80WP1|uniprotkb:Q8BH56|uniprotkb:Q3TG34|uniprotkb:Q3U5X3|uniprotkb:Q3U8I5|uniprotkb:Q3UZ33|uniprotkb:Q5NCI5|uniprotkb:Q5NCI6|uniprotkb:Q5NCI7|ensembl:ENSMUSP00000020769 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:dbnl_mouse(display_long)|uniprotkb:Dbnl(gene name)|psi-mi:Dbnl(display_short)|uniprotkb:Abp1(gene name synonym)|uniprotkb:Sh3p7(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Actin-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001139780.1|refseq:NP_001139781.1|refseq:NP_038838.1|dip:DIP-39835N|ensembl:ENSMUSG00000020476(gene)|ensembl:ENSMUST00000020769(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|interpro:IPR035717|interpro:IPR036028|mint:Q62418|reactome:R-MMU-264870|reactome:R-MMU-6794361|reactome:R-MMU-6798695|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:uRFrfUfKF7cfhsrbleRauR33+g810090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P20152 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:B0V2N5 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282703|ensembl:ENSMUSP00000117855 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:b0v2n5_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000136282(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:IFNL/fdFkFgPLkuNu2kGdtcHDPE10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3ULI3 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282992 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3uli3_mouse(display_long)|uniprotkb:Psmd9(gene name)|psi-mi:Psmd9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036034|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR035269|interpro:IPR040815|interpro:IPR041489 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:HicpgjNRuan1NAeBMremUeQxSps10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P63101 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P28843 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282925|uniprotkb:Q3U514|ensembl:ENSMUSP00000044050 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:dpp4_mouse(display_long)|uniprotkb:Dpp4(gene name)|psi-mi:Dpp4(display_short)|uniprotkb:Cd26(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV(gene name synonym)|uniprotkb:T-cell activation antigen CD26(gene name synonym)|uniprotkb:Thymocyte-activating molecule(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 uniprotkb:A2AS84(uniprot-removed-ac)|refseq:NP_034204.1|refseq:NP_001153015.1|ensembl:ENSMUSG00000035000(gene)|ensembl:ENSMUST00000047812(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0002337"(B-1a B cell differentiation)|go:"GO:0002709"(regulation of T cell mediated immunity)|go:"GO:0002717"(positive regulation of natural killer cell mediated immunity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042110"(T cell activation)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0051234"(establishment of localization)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR029058|mint:P28843|reactome:R-MMU-381771|reactome:R-MMU-400511|interpro:IPR040522 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:HkXFHajJVVYWSVJNiP1apT5XaSY10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:O70456 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1544118|uniprotkb:Q3TEZ1|ensembl:ENSMUSP00000050374 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:1433s_mouse(display_long)|uniprotkb:Sfn(gene name)|psi-mi:Sfn(display_short)|uniprotkb:Mkrn3(gene name synonym)|uniprotkb:Stratifin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_061224.2|ensembl:ENSMUSG00000047281(gene)|ensembl:ENSMUST00000057311(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061436"(establishment of skin barrier)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR037435|mint:O70456|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-6804114|reactome:R-MMU-75035|reactome:R-MMU-9614399|go:"GO:0030307"(positive regulation of cell growth) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:6B8XqFSuqdwWT6hYap/ecmwIuaY10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q9QZ83 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-1183650 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P63017 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3TDD8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282742 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3tdd8_mouse(display_long)|uniprotkb:Eif4b(gene name)|psi-mi:Eif4b(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR033107|interpro:IPR000504(RNA recognition motif, RNP-1) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:LDp2wI8Y/zyz/XWpOK757fCNP/I10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3U0V1 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282969|uniprotkb:Q2VPQ6|uniprotkb:Q6P2L2|uniprotkb:E9QKH3|ensembl:ENSMUSP00000007814 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:fubp2_mouse(display_long)|uniprotkb:Khsrp(gene name)|psi-mi:Khsrp(display_short)|uniprotkb:Fubp2(gene name synonym)|uniprotkb:KH type-splicing regulatory protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_034743.3|ensembl:ENSMUSG00000007670(gene)|ensembl:ENSMUST00000007814(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0030425"(dendrite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q3U0V1|reactome:R-MMU-450604 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:snMZYaCxr5k/zzbgZD18vz5RAfs10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q60930 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-444578|ensembl:ENSMUSP00000022293|uniprotkb:Q78MH6|uniprotkb:Q99L98 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:vdac2_mouse(display_long)|uniprotkb:Voltage-dependent anion-selective channel protein 6(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)|uniprotkb:Vdac6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_035825.1|ensembl:ENSMUSG00000021771(gene)|ensembl:ENSMUST00000022293(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:Q60930|reactome:R-MMU-5689880 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:ApSD4TVlagQ1QHePbOZw7J5rmzQ10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3UIA4 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282631 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3uia4_mouse(display_long)|uniprotkb:Aldh1a3(gene name)|psi-mi:Aldh1a3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|refseq:NP_444310.3|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR029510|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0002138"(retinoic acid biosynthetic process)|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0042574"(retinal metabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:QKCmjZFAv8Lqw3HrGNNmcrpIupE10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q6S385 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4281194 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q6s385_mouse(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR036872|interpro:IPR035915|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR018159|refseq:NP_958795.2|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR030269|interpro:IPR001452(Src homology-3)|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:pQbtY/DLUR9KlmXVG0tpoB65mUo10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P60710 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A1E2B8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282145 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a1e2b8_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0005524"(ATP binding)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:ZWP3SAChvtexmuiM2xOxCL9ud0U10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q5EBJ4 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282605|uniprotkb:Q3UVY3|uniprotkb:Q5DTZ8|uniprotkb:Q8C5L8|uniprotkb:Q9CTR3|ensembl:ENSMUSP00000088458 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:ermin_mouse(display_long)|uniprotkb:Ermn(gene name)|psi-mi:Ermn(display_short)|uniprotkb:Kiaa1189(gene name synonym)|uniprotkb:Juxtanodin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0008360"(regulation of cell shape)|go:"GO:0030175"(filopodium)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0033269"(internode region of axon)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0051015"(actin filament binding)|interpro:IPR008954(Moesin)|mint:Q5EBJ4|ensembl:ENSMUSG00000026830(gene)|ensembl:ENSMUST00000090940(transcript)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|refseq:NP_084248.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:q1jZUeZQICrR3zcSGClRKUcvLWA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:A8DUV3 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282803 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:a8duv3_mouse(display_long)|uniprotkb:Hbat1(gene name)|psi-mi:Hbat1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:PbMJ6ngi/QKo4CGt7XQMqTFT6RU10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:B1ARR7 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282940|ensembl:ENSMUSP00000123695 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:b1arr7_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000150175(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|interpro:IPR000941(Enolase)|interpro:IPR020811|interpro:IPR029017 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:S0dKLPHn6prhoALucREHapMA1bE10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q60605 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-445417|ensembl:ENSMUSP00000151693 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:myl6_mouse(display_long)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:Myl6(gene name)|psi-mi:Myl6(display_short)|uniprotkb:Myln(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_034990.1|refseq:NP_001304147.1|ensembl:ENSMUSG00000090841(gene)|ensembl:ENSMUST00000218127(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:Q60605|reactome:R-MMU-445355|reactome:R-MMU-5627123 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:LhE3NUqcuHlOla13C0vjnFZfzy810090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3URG1 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4283004 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3urg1_mouse(display_long)|uniprotkb:Tppp(gene name)|psi-mi:Tppp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_878259.1|interpro:IPR008907(P25-alpha)|interpro:IPR011992(EF-Hand type)|refseq:XP_006517472.1|interpro:IPR030792|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0015631"(tubulin binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051418"(microtubule nucleation by microtubule organizing center)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097427"(microtubule bundle)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:0048471"(perinuclear region of cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:m6g+6uIsfnaSQDNzM4B9FTNwTSA10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:P12787 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-2934751|ensembl:ENSMUSP00000000090|uniprotkb:Q9D2W1 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:cox5a_mouse(display_long)|uniprotkb:Cox5a(gene name)|psi-mi:Cox5a(display_short)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P12787|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|ensembl:ENSMUSG00000000088(gene)|ensembl:ENSMUST00000000090(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_031773.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:TSqMPwzrYDOAB4IRLwU8EcFKdY010090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q05816 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-445356|ensembl:ENSMUSP00000029046 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:fabp5_mouse(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:Keratinocyte lipid-binding protein(gene name synonym)|uniprotkb:Fabp5(gene name)|psi-mi:Fabp5(display_short)|uniprotkb:Fabpe(gene name synonym)|uniprotkb:Klbp(gene name synonym)|uniprotkb:Mal1(gene name synonym)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_034764.1|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|ensembl:ENSMUSG00000027533(gene)|ensembl:ENSMUST00000029046(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q05816|rcsb pdb:4AZN|rcsb pdb:4AZO|rcsb pdb:4AZP|rcsb pdb:4AZQ|reactome:R-MMU-163560|reactome:R-MMU-5362517|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:mEfn6C+ZFCPHXbinfjz8gab64cE10090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:Q3TRX4 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4282819 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:q3trx4_mouse(display_long)|uniprotkb:Palm(gene name)|psi-mi:Palm(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|interpro:IPR004965(Paralemmin)|refseq:NP_001155219.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:HxiXekMeTVWt2bjeFbgzogo/NV810090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AM57 uniprotkb:B1AWD8 intact:EBI-4280712|ensembl:ENSMUSP00000030029 intact:EBI-4283017|ensembl:ENSMUSP00000103481 psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:b1awd8_mouse(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282630|imex:IM-16529-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 refseq:NP_058040.2|ensembl:ENSMUSG00000028478(gene)|ensembl:ENSMUST00000107849(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|interpro:IPR000996(Clathrin light chain) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 rogid:xnErDfRVQoPt3uLr1NM8005QuX010090 intact-crc:3F4C06894A4C94B8|rigid:3Rz1Tj/cxWYMcGvE9Aus5ZuCXCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2APS1 uniprotkb:P99024 intact:EBI-4281603|ensembl:ENSMUSP00000028857 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283196|imex:IM-16529-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:EDF9FFFB7C2F90BC|rigid:9r9Z3I6+X3sQV5yDueY2y30ovW4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2APS1 uniprotkb:Q3UM23 intact:EBI-4281603|ensembl:ENSMUSP00000028857 intact:EBI-4281076 psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283196|imex:IM-16529-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:EDF9FFFB7C2F90BC|rigid:9r9Z3I6+X3sQV5yDueY2y30ovW4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2APS1 uniprotkb:P59240 intact:EBI-4281603|ensembl:ENSMUSP00000028857 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283196|imex:IM-16529-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:EDF9FFFB7C2F90BC|rigid:9r9Z3I6+X3sQV5yDueY2y30ovW4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2APS1 uniprotkb:P63038 intact:EBI-4281603|ensembl:ENSMUSP00000028857 intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4 psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283196|imex:IM-16529-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090 intact-crc:EDF9FFFB7C2F90BC|rigid:9r9Z3I6+X3sQV5yDueY2y30ovW4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2APS1 uniprotkb:A2AM57 intact:EBI-4281603|ensembl:ENSMUSP00000028857 intact:EBI-4280712|ensembl:ENSMUSP00000030029 psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283196|imex:IM-16529-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 intact-crc:EDF9FFFB7C2F90BC|rigid:9r9Z3I6+X3sQV5yDueY2y30ovW4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2APS1 uniprotkb:P05213 intact:EBI-4281603|ensembl:ENSMUSP00000028857 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283196|imex:IM-16529-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:EDF9FFFB7C2F90BC|rigid:9r9Z3I6+X3sQV5yDueY2y30ovW4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6A078 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6A078 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P58252 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773856|uniprotkb:Q544E4|ensembl:ENSMUSP00000046101 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ef2_mouse(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_031933.1|ensembl:ENSMUSG00000034994(gene)|ensembl:ENSMUST00000047864(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P58252|reactome:R-MMU-156902|reactome:R-MMU-5358493|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:910/vo3IRjcncyPD4f43dPtS83o10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O09061 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991712|uniprotkb:Q62038|uniprotkb:Q62039|ensembl:ENSMUSP00000014913 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb1_mouse(display_long)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)|uniprotkb:Psmb1(gene name)|psi-mi:Psmb1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000014769(gene)|ensembl:ENSMUST00000014913(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|mint:O09061|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-75815|refseq:NP_035315.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:CIHxzlrtwKh+f15z5Uf8Bv4yJ0o10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6P9L1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282173 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6p9l1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR006680(Amidohydrolase 1)|interpro:IPR036897|interpro:IPR036914|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR032466|go:"GO:0005524"(ATP binding)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016812"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides")|go:"GO:0016874"(ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:hjrxaxAVU5nojAo6/iZZnfCbv0s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P60335 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-309059|ensembl:ENSMUSP00000054863 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9DBS1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283794|ensembl:ENSMUSP00000032183 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tmm43_mouse(display_long)|uniprotkb:Tmem43(gene name)|psi-mi:Tmem43(display_short)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_083042.1|ensembl:ENSMUSG00000030095(gene)|ensembl:ENSMUST00000032183(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)|mint:Q9DBS1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:4Yd4/Nc+NNe72Yk6enVcLgmZflQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TKK8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283384 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tkk8_mouse(display_long)|uniprotkb:Hook2(gene name)|psi-mi:Hook2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR008636(HOOK)|refseq:NP_001161463.1|interpro:IPR036872|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR043936 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:h6++ZvBm7my4TKBdJPqPLhAoepQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q03265 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q62425 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TL95 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283458 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tl95_mouse(display_long)|uniprotkb:Psma4(gene name)|psi-mi:Psma4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR034647 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:U1I1Q7r0z1Fob9MGc8MTFRkmA1Q10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P49722 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991661|ensembl:ENSMUSP00000129767|uniprotkb:E9Q3A4|uniprotkb:Q6ZWV8 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa2_mouse(display_long)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:Psma2(gene name)|psi-mi:Psma2(display_short)|uniprotkb:Lmpc3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000015671(gene)|ensembl:ENSMUST00000170836(transcript)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|mint:P49722|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-2467813|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|refseq:NP_032970.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nKRiQheHfS3+3anLub61WsVVtFE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P38647 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P10126 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P20029 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P28658 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P05213 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9ERK4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400836|intact:EBI-4283823|ensembl:ENSMUSP00000002790 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:xpo2_mouse(display_long)|uniprotkb:Cse1l(gene name)|psi-mi:Cse1l(display_short)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Xpo2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_076054.1|ensembl:ENSMUSG00000002718(gene)|ensembl:ENSMUST00000002790(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9ERK4 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:vJpTu+2YjwIRrjM3V815K3lZzAg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:B1AQ77 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283738|ensembl:ENSMUSP00000103034 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:b1aq77_mouse(display_long)|uniprotkb:Krt15(gene name)|psi-mi:Krt15(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032495.2|ensembl:ENSMUSG00000054146(gene)|ensembl:ENSMUST00000107411(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:B1AQ77 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1UXzTf4nv5xlyEKtZjxS95LwehE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BHD8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284107|intact:EBI-4286238|uniprotkb:Q3UKB7|uniprotkb:Q8BJT6|uniprotkb:Q8BK38|uniprotkb:Q8C0H6|uniprotkb:Q8R1D5|ensembl:ENSMUSP00000029116 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pcmd2_mouse(display_long)|uniprotkb:Pcmtd2(gene name)|psi-mi:Pcmtd2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_705822.1|uniprotkb:B0R0C8(uniprot-removed-ac)|refseq:NP_001278140.1|ensembl:ENSMUST00000029116(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|ensembl:ENSMUSG00000027589(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:cxvzknx+QmPo2pIM/ZPuYK+uOaE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99MW3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283683|ensembl:ENSMUSP00000043718 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pral1_mouse(display_long)|uniprotkb:Pramel1(gene name)|psi-mi:Pramel1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_113554.1|ensembl:ENSMUSG00000041805(gene)|ensembl:ENSMUST00000037419(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031514"(motile cilium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR026271|interpro:IPR032675 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fuP3Qw5yyHw+wYeuKyVQb8yOuuo10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q059U9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283557 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q059u9_mouse(display_long)|uniprotkb:Akap8(gene name)|psi-mi:Akap8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR034736|refseq:NP_062748.2|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016301"(kinase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:CboiIO6b/r8YM0jLmJbCdzg5S3U10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TN31 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283510 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tn31_mouse(display_long)|uniprotkb:Psma7(gene name)|psi-mi:Psma7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR035190 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:k9urd+gcZEJJTjcA4lueka9Glzg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2AKU9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283992|ensembl:ENSMUSP00000026887 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2aku9_mouse(display_long)|uniprotkb:Atp5c1(gene name)|psi-mi:Atp5c1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:XP_006497373.1|ensembl:ENSMUSG00000025781(gene)|ensembl:ENSMUST00000026887(transcript)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:rLHMVagZZkFdZr2ZC5vAc2Na32E10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P20664 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-848742|ensembl:ENSMUSP00000026461 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1ot482OC79gyXLWhgZIAppJwPzw10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P49722 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991661|ensembl:ENSMUSP00000129767|uniprotkb:E9Q3A4|uniprotkb:Q6ZWV8 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa2_mouse(display_long)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:Psma2(gene name)|psi-mi:Psma2(display_short)|uniprotkb:Lmpc3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000015671(gene)|ensembl:ENSMUST00000170836(transcript)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|mint:P49722|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-2467813|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|refseq:NP_032970.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nKRiQheHfS3+3anLub61WsVVtFE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 intact:EBI-4283265 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 - psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:b1aty0_mouse(display_short)|psi-mi:EBI-4283265(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:RP23-82I5.1-002(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 uniprotkb:B1ATY0(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:xCmIOr1f0PlfORSnmajCADcOpeg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99JY0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299517|ensembl:ENSMUSP00000026841|ensembl:ENSMUSP00000110431|ensembl:ENSMUSP00000110434|uniprotkb:Q3TEH9|uniprotkb:Q8BJI5|uniprotkb:Q8BJM0|uniprotkb:Q8BK52 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:echb_mouse(display_long)|uniprotkb:Hadhb(gene name)|psi-mi:Hadhb(display_short)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000059447(gene)|ensembl:ENSMUST00000026841(transcript)|ensembl:ENSMUST00000114783(transcript)|ensembl:ENSMUST00000114786(transcript)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q99JY0|reactome:R-MMU-1482798|reactome:R-MMU-77285|reactome:R-MMU-77305|reactome:R-MMU-77310|reactome:R-MMU-77346|reactome:R-MMU-77348|reactome:R-MMU-77350|interpro:IPR002155(Thiolase)|refseq:NP_663533.1|refseq:NP_001276727.1|refseq:NP_001276728.1|refseq:XP_017176317.1|refseq:XP_017176318.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:XpJTZFG2xL1ouAgOyU562mqD64I10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P38647 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P17710 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773368|uniprotkb:E9PXQ3|uniprotkb:Q61659|uniprotkb:Q64476|uniprotkb:Q64479 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hxk1_mouse(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Hexokinase, tumor isozyme(gene name synonym)|uniprotkb:Hk1(gene name)|psi-mi:Hk1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR019807|interpro:IPR022672|refseq:XP_006513305.1|refseq:XP_006513306.1|refseq:XP_006513307.1|refseq:XP_006513308.1|interpro:IPR043129|mint:P17710|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|reactome:R-MMU-70171 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:x4T9LnTLPxq69q+uvfTwLT8gCn410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O55143 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-770763|uniprotkb:Q9R2A9|uniprotkb:Q9WUT5|ensembl:ENSMUSP00000031423|ensembl:ENSMUSP00000135935 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:at2a2_mouse(display_long)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)|uniprotkb:Atp2a2(gene name)|psi-mi:Atp2a2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001103610.1|refseq:NP_033852.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O55143|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000029467(gene)|ensembl:ENSMUST00000031423(transcript)|ensembl:ENSMUST00000179939(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:LJG8hpHG2pO9ePikEKYbhsuCeRI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2AM57 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280712|ensembl:ENSMUSP00000030029 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:E9Q557 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-688046|ensembl:ENSMUSP00000115062 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)" figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P70168 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-540580|uniprotkb:Q62117|uniprotkb:Q6GTI5|ensembl:ENSMUSP00000001479 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:imb1_mouse(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:SCG(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Impnb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032405.3|ensembl:ENSMUSG00000001440(gene)|ensembl:ENSMUST00000001479(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|reactome:R-MMU-2995383|reactome:R-MMU-6798695|reactome:R-MMU-909733|reactome:R-MMU-1655829|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:P70168|rcsb pdb:1GCJ|rcsb pdb:1UKL|go:"GO:0019894"(kinesin binding)|reactome:R-MMU-140342|dip:DIP-33404N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:rYDCcZYUZp8TbcpyJE7pfz5+bvo10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O35382 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772648|ensembl:ENSMUSP00000051965 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:exoc4_mouse(display_long)|uniprotkb:Exocyst complex component Sec8(gene name synonym)|uniprotkb:Exoc4(gene name)|psi-mi:Exoc4(display_short)|uniprotkb:Sec8(gene name synonym)|uniprotkb:Sec8l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033174.2|dip:DIP-32368N|ensembl:ENSMUSG00000029763(gene)|ensembl:ENSMUST00000052266(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043209"(myelin sheath)|go:"GO:0044091"(membrane biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:O35382|reactome:R-MMU-264876|reactome:R-MMU-5620916 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:kgplLpzVE6TdHg877TyXAlCXb7g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q542D9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284037 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q542d9_mouse(display_long)|uniprotkb:Tfrc(gene name)|psi-mi:Tfrc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036757|interpro:IPR037324|refseq:NP_035768.1|interpro:IPR007484(Peptidase M28)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|refseq:XP_006522062.1|interpro:IPR029513|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR039373 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VFnVdK5loK3683nCBW7vxIe7M6Y10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TT04 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283472 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tt04_mouse(display_long)|uniprotkb:Ipo5(gene name)|psi-mi:Ipo5(display_short)|uniprotkb:Ranbp5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR040928|interpro:IPR040122|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR041389 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6mqeNZ0FdCacBeh/ibNMpsjWIL410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P59913 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282915|ensembl:ENSMUSP00000059261 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pcmd1_mouse(display_long)|uniprotkb:Pcmtd1(gene name)|psi-mi:Pcmtd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_898849.1|ensembl:ENSMUSG00000051285(gene)|ensembl:ENSMUST00000061280(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HCK1zY5gjRef1W5wg+vWdKvmt9g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63037 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UM57 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283692 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3um57_mouse(display_long)|uniprotkb:Cand2(gene name)|psi-mi:Cand2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR039852|interpro:IPR016024(Armadillo-type fold)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|go:"GO:0010265"(SCF complex assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:/UXXIyXNXp+cLPcGPzkfIXEN5iQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9Z2X1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TUI9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283623 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tui9_mouse(display_long)|uniprotkb:Psma5(gene name)|psi-mi:Psma5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR033812 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:O/dmUXCVjKkoF5dj+FYULD+lzLk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68368 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U2G2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284094|ensembl:ENSMUSP00000020630 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u2g2_mouse(display_long)|uniprotkb:Hspa4(gene name)|psi-mi:Hspa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032326.3|ensembl:ENSMUSG00000020361(gene)|ensembl:ENSMUST00000020630(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:hjeg4KTmOF9Jzi8+sGvPTU7w35g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q69ZL7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283497 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q69zl7_mouse(display_long)|uniprotkb:Wdr35(gene name)|psi-mi:Wdr35(display_short)|uniprotkb:mKIAA1336(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036322|interpro:IPR024977|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR017233(WD repeat protein 35) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:3RhuzFGhRDHWCC1ssuwD+H+Vm9o10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68368 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TFF0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280988 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tff0_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|go:"GO:0005524"(ATP binding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0006457"(protein folding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:RZ+srevvpWpXwpx29WWzxPigMlc10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 intact:EBI-4283403 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 - psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2bfa6_mouse(display_short)|psi-mi:EBI-4283403(display_long)|uniprotkb:Naglu(gene name)|psi-mi:Naglu(display_short)|uniprotkb:RP23-440M18.1-001(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 uniprotkb:A2BFA6(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Wk3d0MOX4aDXePOotmzQPwoS8eQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2A5R2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283806|ensembl:ENSMUSP00000096677 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:big2_mouse(display_long)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Big2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001078964.1|ensembl:ENSMUSG00000074582(gene)|ensembl:ENSMUST00000099078(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:kHCteybcE9xmumNV1/XeKctG6sA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O70435 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991671|ensembl:ENSMUSP00000125548 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa3_mouse(display_long)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:Proteasome subunit K(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Psma3(gene name)|psi-mi:Psma3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035314.3|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|interpro:IPR023332|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|interpro:IPR029055|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|interpro:IPR037555|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|ensembl:ENSMUSG00000060073(gene)|ensembl:ENSMUST00000160027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|refseq:XP_017170485.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:NgV6tyZ0v25UGZ5FkGZNNLMJVjQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6P1Y9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283275|ensembl:ENSMUSP00000109121 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6p1y9_mouse(display_long)|uniprotkb:Exoc1(gene name)|psi-mi:Exoc1(display_short)|uniprotkb:Sec3l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_081546.1|ensembl:ENSMUSG00000036435(gene)|ensembl:ENSMUST00000113493(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q6P1Y9|refseq:NP_001276699.1|refseq:NP_001276700.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:2HAmUJdq4vLcizqFoiFx9IwMC3010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P07901 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99P31 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283763|uniprotkb:Q9CYV8|ensembl:ENSMUSP00000078886 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hpbp1_mouse(display_long)|uniprotkb:Hspbp1(gene name)|psi-mi:Hspbp1(display_short)|uniprotkb:Hspbp(gene name synonym)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_077134.1|refseq:XP_006540351.1|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q99P31|ensembl:ENSMUSG00000063802(gene)|ensembl:ENSMUST00000079970(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0031398"(positive regulation of protein ubiquitination) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nMkL4DXY9VfPIRdEesUfaGQ7ofY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q60692 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991777|uniprotkb:Q3V240|uniprotkb:Q60693|uniprotkb:Q8BJX9|uniprotkb:Q91VH5|ensembl:ENSMUSP00000018430|intact:EBI-4282155 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb6_mouse(display_long)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Psmb6(gene name)|psi-mi:Psmb6(display_short)|uniprotkb:Lmp19(gene name synonym)|uniprotkb:Low molecular mass protein 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-174178|reactome:R-MMU-5676590|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-5687128|ensembl:ENSMUSG00000018286(gene)|ensembl:ENSMUST00000018430(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:Q60692|rcsb pdb:3UNB|rcsb pdb:3UNE|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|go:"GO:0005839"(proteasome core complex)|reactome:R-MMU-174154|refseq:NP_032972.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:z+HBCqJQpl+Rkyn8MS3YM0V1TeQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2RSB1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283571 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2rsb1_mouse(display_long)|uniprotkb:Nap1l4(gene name)|psi-mi:Nap1l4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR037231|interpro:IPR002164("Nucleosome assembly protein (NAP)")|refseq:NP_032698.1|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:wEHrLDNg3hwUMaUS8fNw0+AjBz410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P14602 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299023|ensembl:ENSMUSP00000005077 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9WTI7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P10126 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P33610 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9QUM9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991694|uniprotkb:Q0VGS3|uniprotkb:Q3TT07|uniprotkb:Q3U6Y2|ensembl:ENSMUSP00000021412 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa6_mouse(display_long)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:Psma6(gene name)|psi-mi:Psma6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036098.1|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:Q9QUM9|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|ensembl:ENSMUSG00000021024(gene)|ensembl:ENSMUST00000021412(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|reactome:R-MMU-69481|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VgUJoxRfxHDdUz0LNg/kcEY95a010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q80UU9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1634859|ensembl:ENSMUSP00000056643 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pgrc2_mouse(display_long)|uniprotkb:Pgrmc2(gene name)|psi-mi:Pgrmc2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_081834.1|ensembl:ENSMUSG00000049940(gene)|ensembl:ENSMUST00000058578(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|reactome:R-MMU-8980692|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:KIn48KpS0Z3E1uqRAIbFZVL/nnc10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UDN8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283418 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3udn8_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR003649(B-box, C-terminal)|interpro:IPR001487(Bromodomain)|interpro:IPR019786|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VPtUcH9n/fF4qpCKwWPIfuGxEVU10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UMM1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283969 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3umm1_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_080749.2|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR002453(Beta tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR036525|interpro:IPR037103|interpro:IPR023123|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UM57 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283692 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3um57_mouse(display_long)|uniprotkb:Cand2(gene name)|psi-mi:Cand2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR039852|interpro:IPR016024(Armadillo-type fold)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|go:"GO:0010265"(SCF complex assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:/UXXIyXNXp+cLPcGPzkfIXEN5iQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A6ZI44 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283485|ensembl:ENSMUSP00000084846 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a6zi44_mouse(display_long)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001170778.1|refseq:XP_006507272.1|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000087566(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035094"(response to nicotine)|go:"GO:0043627"(response to estrogen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:QfjcGwfzA6vJ+Ip6oyWZf4ZCtQM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BFR5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6PCZ4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283582|uniprotkb:Q8BG82|uniprotkb:Q8BQ37|uniprotkb:Q99PB2|ensembl:ENSMUSP00000094078 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:mage1_mouse(display_long)|uniprotkb:Alpha-dystrobrevin-associated MAGE Protein(gene name synonym)|uniprotkb:MAGE-E1 antigen(gene name synonym)|uniprotkb:Magee1(gene name)|psi-mi:Magee1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_444431.3|ensembl:ENSMUSG00000031227(gene)|ensembl:ENSMUST00000033578(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dkss1SnnVRW1H6rfzgDHI28OiIg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TPX4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-775555|uniprotkb:Q80VK3|ensembl:ENSMUSP00000125434 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:exoc5_mouse(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:Exoc5(gene name)|psi-mi:Exoc5(display_short)|uniprotkb:Sec10l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_997097.1|ensembl:ENSMUSG00000061244(gene)|ensembl:ENSMUST00000162175(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|reactome:R-MMU-264876|reactome:R-MMU-5620916 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:lLxyXBlor+hHByz1xwPbJBRic1g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68372 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UM23 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281076 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q4G0B8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284006 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q4g0b8_mouse(display_long)|uniprotkb:Ipo9(gene name)|psi-mi:Ipo9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR016024(Armadillo-type fold)|interpro:IPR001494(Importin-beta, N-terminal)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:j2cqUUoc4afIkOHfcx4dDYbDT+A10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63168 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-349121|uniprotkb:Q15701|ensembl:ENSMUSP00000107720|ensembl:ENSMUSP00000009157|uniprotkb:Q3UGE7 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:dyl1_mouse(display_long)|uniprotkb:Dynll1(gene name)|psi-mi:Dynll1(display_short)|uniprotkb:Dlc1(gene name synonym)|uniprotkb:Dnclc1(gene name synonym)|uniprotkb:Dncl1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_062656.3|ensembl:ENSMUST00000009157(transcript)|ensembl:ENSMUST00000112090(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000009013(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63168|reactome:R-MMU-111446|reactome:R-MMU-141444|reactome:R-MMU-1632852|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv8010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q61699 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772450|uniprotkb:Q3TNS2|uniprotkb:Q3UIY8|uniprotkb:Q62578|uniprotkb:Q62579|uniprotkb:Q6A0A5|uniprotkb:Q8C430|uniprotkb:Q8VCW6|ensembl:ENSMUSP00000144413|ensembl:ENSMUSP00000144654 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hs105_mouse(display_long)|uniprotkb:Heat shock-related 100 kDa protein E7I(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:42 degrees C-HSP(gene name synonym)|uniprotkb:Hsph1(gene name)|psi-mi:Hsph1(display_short)|uniprotkb:Hsp105(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Kiaa0201(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_038587.2|refseq:NP_001334463.1|dip:DIP-32354N|ensembl:ENSMUSG00000029657(gene)|ensembl:ENSMUST00000201452(transcript)|ensembl:ENSMUST00000202361(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q61699|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pZByRgd8f5XdmB138rYxEMrwkRY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63168 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-349121|uniprotkb:Q15701|ensembl:ENSMUSP00000107720|ensembl:ENSMUSP00000009157|uniprotkb:Q3UGE7 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:dyl1_mouse(display_long)|uniprotkb:Dynll1(gene name)|psi-mi:Dynll1(display_short)|uniprotkb:Dlc1(gene name synonym)|uniprotkb:Dnclc1(gene name synonym)|uniprotkb:Dncl1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_062656.3|ensembl:ENSMUST00000009157(transcript)|ensembl:ENSMUST00000112090(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000009013(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63168|reactome:R-MMU-111446|reactome:R-MMU-141444|reactome:R-MMU-1632852|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv8010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2RSB1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283571 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2rsb1_mouse(display_long)|uniprotkb:Nap1l4(gene name)|psi-mi:Nap1l4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR037231|interpro:IPR002164("Nucleosome assembly protein (NAP)")|refseq:NP_032698.1|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:wEHrLDNg3hwUMaUS8fNw0+AjBz410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TUI9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283623 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tui9_mouse(display_long)|uniprotkb:Psma5(gene name)|psi-mi:Psma5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR033812 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:O/dmUXCVjKkoF5dj+FYULD+lzLk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BGS1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283324|uniprotkb:Q3TJG0|uniprotkb:Q69ZG8|uniprotkb:Q8BSC9|uniprotkb:Q99KZ8|ensembl:ENSMUSP00000058966 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:e41l5_mouse(display_long)|uniprotkb:Epb4.1l5(gene name synonym)|uniprotkb:Kiaa1548(gene name synonym)|uniprotkb:Epb41l5(gene name)|psi-mi:Epb41l5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0001756"(somitogenesis)|refseq:NP_001106887.1|refseq:NP_663481.2|refseq:XP_006529460.1|refseq:XP_006529461.1|refseq:XP_006529463.1|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0048319"(axial mesoderm morphogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|ensembl:ENSMUSG00000026383(gene)|ensembl:ENSMUST00000052404(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|interpro:IPR030694|mint:Q8BGS1|reactome:R-MMU-6794361|interpro:IPR035963 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pt6yMNx5+txA950Eal6TthTO5sM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3THL2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283753 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3thl2_mouse(display_long)|uniprotkb:Psma7(gene name)|psi-mi:Psma7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|refseq:NP_001276405.1|interpro:IPR029055|interpro:IPR035190|mint:Q3THL2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:40phN4FYZWAmjdKRst1nqlt9N+U10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q545G0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283248 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q545g0_mouse(display_long)|uniprotkb:Psmb3(gene name)|psi-mi:Psmb3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036101.1|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR033811 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:LLhBgxXML1O4gyh9co1+55VyPM410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2AKU9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283992|ensembl:ENSMUSP00000026887 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2aku9_mouse(display_long)|uniprotkb:Atp5c1(gene name)|psi-mi:Atp5c1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:XP_006497373.1|ensembl:ENSMUSG00000025781(gene)|ensembl:ENSMUST00000026887(transcript)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:rLHMVagZZkFdZr2ZC5vAc2Na32E10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BWT1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:15aWO97WJBNGYD449bAgjVjkgTY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q64512 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284057|uniprotkb:Q61494|uniprotkb:Q62135|uniprotkb:Q64499 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ptn13_mouse(display_long)|uniprotkb:Ptpn13(gene name)|psi-mi:Ptpn13(display_short)|uniprotkb:Ptp14(gene name synonym)|uniprotkb:PTP36(gene name synonym)|uniprotkb:Protein tyrosine phosphatase DPZPTP(gene name synonym)|uniprotkb:Protein tyrosine phosphatase PTP-BL(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase RIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR035963|interpro:IPR036034|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|rcsb pdb:6GBD|rcsb pdb:6GBE|refseq:NP_035334.2|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011019(KIND)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|rcsb pdb:1GM1|rcsb pdb:1OZI|rcsb pdb:1VJ6|interpro:IPR029021|interpro:IPR029071|go:"GO:0001650"(fibrillar center)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0030496"(midbody)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|reactome:R-MMU-1660499|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:cPfYanrHD/RnZ+Akt306Ua1CQxI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P70195 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991788|intact:EBI-4283777|uniprotkb:O09084|uniprotkb:Q542F7|uniprotkb:Q9CZH4|uniprotkb:Q9DCF7|ensembl:ENSMUSP00000028083 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb7_mouse(display_long)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Psmb7(gene name)|psi-mi:Psmb7(display_short)|uniprotkb:Mmc14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000026750(gene)|ensembl:ENSMUST00000028083(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:P70195|rcsb pdb:3UNB|rcsb pdb:3UNE|reactome:R-MMU-1169091|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-1234176|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-8951664|refseq:NP_035317.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VPAUvXAFM5Dz/Ebh+0KgCf5GFPA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A5JUZ1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280663 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A1E2B8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282145 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a1e2b8_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0005524"(ATP binding)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ZWP3SAChvtexmuiM2xOxCL9ud0U10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63017 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O55234 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991760|uniprotkb:Q9R1P2|uniprotkb:Q3UZI1|uniprotkb:Q91X53|uniprotkb:Q9CWR4|ensembl:ENSMUSP00000022803 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb5_mouse(display_long)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Psmb5(gene name)|psi-mi:Psmb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000022193(gene)|ensembl:ENSMUST00000022803(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0005813"(centrosome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:O55234|rcsb pdb:3UNB|rcsb pdb:3UNE|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-195253|reactome:R-MMU-68949|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-69017|reactome:R-MMU-8948751|reactome:R-MMU-69481|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|refseq:NP_035316.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fYhsgekPQbsqZwwxI3ORdi9Sn0k10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UHQ5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2550458 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3uhq5_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:Gcn1l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|refseq:NP_766307.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1t/G1ybGLV/oHg/3GijS0N8AWjk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q5SSW2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283842|uniprotkb:Q3TER7|uniprotkb:Q3V2B7|uniprotkb:Q6ZQJ7|uniprotkb:Q7TMY9|uniprotkb:Q8K0K0|uniprotkb:Q99KM2|uniprotkb:Q9ESY1|ensembl:ENSMUSP00000045460|uniprotkb:C4IXU5 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psme4_mouse(display_long)|uniprotkb:Psme4(gene name)|psi-mi:Psme4(display_short)|uniprotkb:Kiaa0077(gene name synonym)|uniprotkb:Proteasome activator PA200(gene name synonym)|uniprotkb:Protein TEMO(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_598774.2|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000040850(gene)|ensembl:ENSMUST00000041231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032430|interpro:IPR035309|mint:Q5SSW2|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:LQiV+yvUQhD6KkKZGnAHj93ktyo10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6P9L1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282173 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6p9l1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR006680(Amidohydrolase 1)|interpro:IPR036897|interpro:IPR036914|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR032466|go:"GO:0005524"(ATP binding)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016812"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides")|go:"GO:0016874"(ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:hjrxaxAVU5nojAo6/iZZnfCbv0s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P28656 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-645055|uniprotkb:Q3UL14|ensembl:ENSMUSP00000070068|ensembl:ENSMUSP00000151750|ensembl:ENSMUSP00000151972 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:np1l1_mouse(display_long)|uniprotkb:NAP-1-related protein(gene name synonym)|uniprotkb:Brain protein DN38(gene name synonym)|uniprotkb:Nap1l1(gene name)|psi-mi:Nap1l1(display_short)|uniprotkb:Nrp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_056596.1|ensembl:ENSMUSG00000058799(gene)|ensembl:ENSMUST00000065917(transcript)|ensembl:ENSMUST00000217908(transcript)|ensembl:ENSMUST00000218828(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019900"(kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P28656 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AW+O1Tr5ZJ+2UVKVdK/5fqXesSs10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9R1P3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991720|ensembl:ENSMUSP00000030642|intact:EBI-4283666 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb2_mouse(display_long)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Psmb2(gene name)|psi-mi:Psmb2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036100.3|ensembl:ENSMUSG00000028837(gene)|ensembl:ENSMUST00000030642(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:Q9R1P3|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-5610780|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Djblc01whZPk1T8eIesG6alQQZs10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99KN2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283601|uniprotkb:Q9DCZ7|ensembl:ENSMUSP00000003759 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ciao1_mouse(display_long)|uniprotkb:Ciao1(gene name)|psi-mi:Ciao1(display_short)|uniprotkb:Wdr39(gene name synonym)|uniprotkb:WD repeat-containing protein 39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_079572.2|ensembl:ENSMUSG00000003662(gene)|ensembl:ENSMUST00000003759(transcript)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:Q99KN2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:zIBtbbwc4hWRw+uGBN5090nQ1Nk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9EPL8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2550269|ensembl:ENSMUSP00000081782|uniprotkb:Q7TN09|uniprotkb:Q7TQ63|uniprotkb:Q8BKD8|uniprotkb:Q8BYI0 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ipo7_mouse(display_long)|uniprotkb:Ipo7(gene name)|psi-mi:Ipo7(display_short)|uniprotkb:Ranbp7(gene name synonym)|uniprotkb:Ran-binding protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000066232(gene)|ensembl:ENSMUST00000084731(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9EPL8|refseq:NP_852658.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:YOGtbOzeE6Oq5T0J42GWW7fH9H010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1G4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282128 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u1g4_mouse(display_long)|uniprotkb:Exoc1(gene name)|psi-mi:Exoc1(display_short)|uniprotkb:Sec3l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|interpro:IPR019160|interpro:IPR028258 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:K9P9YJ1MVDPgVMEvI6DXMm18qOI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BFW7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283284|uniprotkb:Q5U407|uniprotkb:Q8BHI1|uniprotkb:Q8BKI0|uniprotkb:Q8BKN2|uniprotkb:Q8BLF4|uniprotkb:Q8BLG3|uniprotkb:Q8C101|ensembl:ENSMUSP00000036304|ensembl:ENSMUSP00000078005 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:lpp_mouse(display_long)|uniprotkb:Lpp(gene name)|psi-mi:Lpp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001139424.1|refseq:NP_001139426.1|refseq:NP_848780.3|refseq:XP_006522020.1|ensembl:ENSMUSG00000033306(gene)|ensembl:ENSMUST00000078988(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0046872"(metal ion binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028771|mint:Q8BFW7|ensembl:ENSMUST00000038053(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:XAdPnciv19gtS4vVm6mv1bIfOE810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1G4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282128 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u1g4_mouse(display_long)|uniprotkb:Exoc1(gene name)|psi-mi:Exoc1(display_short)|uniprotkb:Sec3l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|interpro:IPR019160|interpro:IPR028258 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:K9P9YJ1MVDPgVMEvI6DXMm18qOI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UMM1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283969 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3umm1_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_080749.2|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR002453(Beta tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR036525|interpro:IPR037103|interpro:IPR023123|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q80T84 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283393 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q80t84_mouse(display_long)|uniprotkb:Mroh1(gene name)|psi-mi:Mroh1(display_short)|uniprotkb:Heatr7a(gene name synonym)|uniprotkb:mKIAA1833(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nX2FRMe6J+ILVjw/r+kYcJDXtoM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1J4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2552275|ensembl:ENSMUSP00000025649|uniprotkb:Q99LV3|uniprotkb:Q9QYK0|uniprotkb:Q3U8G3|uniprotkb:Q9WV39|uniprotkb:Q3UJC4|uniprotkb:Q3U4D0 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ddb1_mouse(display_long)|uniprotkb:Ddb1(gene name)|psi-mi:Ddb1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000024740(gene)|ensembl:ENSMUST00000025649(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_056550.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|mint:Q3U1J4|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|go:"GO:0005654"(nucleoplasm)|dip:DIP-56812N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dvNwCrG9In1FV2j/+PrsSMvqFnk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BHD8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284107|intact:EBI-4286238|uniprotkb:Q3UKB7|uniprotkb:Q8BJT6|uniprotkb:Q8BK38|uniprotkb:Q8C0H6|uniprotkb:Q8R1D5|ensembl:ENSMUSP00000029116 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pcmd2_mouse(display_long)|uniprotkb:Pcmtd2(gene name)|psi-mi:Pcmtd2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_705822.1|uniprotkb:B0R0C8(uniprot-removed-ac)|refseq:NP_001278140.1|ensembl:ENSMUST00000029116(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|ensembl:ENSMUSG00000027589(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:cxvzknx+QmPo2pIM/ZPuYK+uOaE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A0JNT0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283311 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a0jnt0_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR036770|refseq:NP_001268906.1|refseq:NP_001268907.1|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:FES9DsulJzFGdCImT2oalvQfUok10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U3Z4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283523 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u3z4_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:Gcn1l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Zu8cbDTfjKZt28FQLO+nWCcNZAA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P07901 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q7TN75 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283936|uniprotkb:Q9EQ11 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:peg10_mouse(display_long)|uniprotkb:Peg10(gene name)|psi-mi:Peg10(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Mart2(gene name synonym)|uniprotkb:Mar2(gene name synonym)|uniprotkb:Mef3l1(gene name synonym)|uniprotkb:Rgag3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001035701.1|refseq:NP_570947.2|interpro:IPR021109|interpro:IPR005162(Retrotransposon gag protein)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR032567|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Ay55/wBT5JiR1ULjKC9cEymVYss10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6NWV3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283871|uniprotkb:Q6KAU2|uniprotkb:Q8C8U5|uniprotkb:Q8CD77|ensembl:ENSMUSP00000108547 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:if122_mouse(display_long)|uniprotkb:Ift122(gene name)|psi-mi:Ift122(display_short)|uniprotkb:Wdr10(gene name synonym)|uniprotkb:WD repeat-containing protein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001161235.1|refseq:NP_112454.2|ensembl:ENSMUSG00000030323(gene)|ensembl:ENSMUST00000112925(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0007227"(signal transduction downstream of smoothened)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035720"(intraciliary anterograde transport)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060830"(ciliary receptor clustering involved in smoothened signaling pathway)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039857|reactome:R-MMU-5610787|reactome:R-MMU-5620924 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:MNf6twspuHEgALFBPLUSL4bnt9s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P99026 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991752|uniprotkb:Q3THC0|uniprotkb:Q3THI3|uniprotkb:Q3U0S0|uniprotkb:Q3UVQ4|uniprotkb:Q62008|uniprotkb:Q8BK27|uniprotkb:Q91VV7|ensembl:ENSMUSP00000005923 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb4_mouse(display_long)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:Psmb4(gene name)|psi-mi:Psmb4(display_short)|uniprotkb:Lmp3(gene name synonym)|uniprotkb:Low molecular mass protein 3(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032971.2|ensembl:ENSMUSG00000005779(gene)|ensembl:ENSMUST00000005923(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P99026|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-4608870|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|dip:DIP-35152N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:jTLU7QS1B0YP4ZedlzxXtnhioRQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TJA9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283904 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tja9_mouse(display_long)|uniprotkb:Dnaja3(gene name)|psi-mi:Dnaja3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001128584.1|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR036410|interpro:IPR036869|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:imDckk2w4uXfQciLWUxkieJk2vI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TFF0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280988 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tff0_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|go:"GO:0005524"(ATP binding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0006457"(protein folding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:RZ+srevvpWpXwpx29WWzxPigMlc10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6NWV3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283871|uniprotkb:Q6KAU2|uniprotkb:Q8C8U5|uniprotkb:Q8CD77|ensembl:ENSMUSP00000108547 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:if122_mouse(display_long)|uniprotkb:Ift122(gene name)|psi-mi:Ift122(display_short)|uniprotkb:Wdr10(gene name synonym)|uniprotkb:WD repeat-containing protein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001161235.1|refseq:NP_112454.2|ensembl:ENSMUSG00000030323(gene)|ensembl:ENSMUST00000112925(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0007227"(signal transduction downstream of smoothened)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035720"(intraciliary anterograde transport)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060830"(ciliary receptor clustering involved in smoothened signaling pathway)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039857|reactome:R-MMU-5610787|reactome:R-MMU-5620924 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:MNf6twspuHEgALFBPLUSL4bnt9s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q059U9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283557 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q059u9_mouse(display_long)|uniprotkb:Akap8(gene name)|psi-mi:Akap8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR034736|refseq:NP_062748.2|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016301"(kinase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:CboiIO6b/r8YM0jLmJbCdzg5S3U10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9D071 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283533|uniprotkb:Q925N8|uniprotkb:Q9CWX3|uniprotkb:F8WHX3|ensembl:ENSMUSP00000130900 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:mms19_mouse(display_long)|uniprotkb:Mms19(gene name)|psi-mi:Mms19(display_short)|uniprotkb:Mms19l(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_082428.1|ensembl:ENSMUSG00000025159(gene)|ensembl:ENSMUST00000171561(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|rcsb pdb:6TBL|rcsb pdb:6TC0 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:S24j+ddJAniA1XEtuEoZvrT6K7s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q69ZL7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283497 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q69zl7_mouse(display_long)|uniprotkb:Wdr35(gene name)|psi-mi:Wdr35(display_short)|uniprotkb:mKIAA1336(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036322|interpro:IPR024977|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR017233(WD repeat protein 35) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:3RhuzFGhRDHWCC1ssuwD+H+Vm9o10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 intact:EBI-4283265 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 - psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:b1aty0_mouse(display_short)|psi-mi:EBI-4283265(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:RP23-82I5.1-002(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 uniprotkb:B1ATY0(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:xCmIOr1f0PlfORSnmajCADcOpeg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TN31 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283510 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tn31_mouse(display_long)|uniprotkb:Psma7(gene name)|psi-mi:Psma7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR035190 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:k9urd+gcZEJJTjcA4lueka9Glzg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P28656 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-645055|uniprotkb:Q3UL14|ensembl:ENSMUSP00000070068|ensembl:ENSMUSP00000151750|ensembl:ENSMUSP00000151972 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:np1l1_mouse(display_long)|uniprotkb:NAP-1-related protein(gene name synonym)|uniprotkb:Brain protein DN38(gene name synonym)|uniprotkb:Nap1l1(gene name)|psi-mi:Nap1l1(display_short)|uniprotkb:Nrp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_056596.1|ensembl:ENSMUSG00000058799(gene)|ensembl:ENSMUST00000065917(transcript)|ensembl:ENSMUST00000217908(transcript)|ensembl:ENSMUST00000218828(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019900"(kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P28656 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AW+O1Tr5ZJ+2UVKVdK/5fqXesSs10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6PCZ4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283582|uniprotkb:Q8BG82|uniprotkb:Q8BQ37|uniprotkb:Q99PB2|ensembl:ENSMUSP00000094078 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:mage1_mouse(display_long)|uniprotkb:Alpha-dystrobrevin-associated MAGE Protein(gene name synonym)|uniprotkb:MAGE-E1 antigen(gene name synonym)|uniprotkb:Magee1(gene name)|psi-mi:Magee1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_444431.3|ensembl:ENSMUSG00000031227(gene)|ensembl:ENSMUST00000033578(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dkss1SnnVRW1H6rfzgDHI28OiIg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9DBS1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283794|ensembl:ENSMUSP00000032183 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tmm43_mouse(display_long)|uniprotkb:Tmem43(gene name)|psi-mi:Tmem43(display_short)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_083042.1|ensembl:ENSMUSG00000030095(gene)|ensembl:ENSMUST00000032183(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)|mint:Q9DBS1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:4Yd4/Nc+NNe72Yk6enVcLgmZflQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TT04 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283472 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tt04_mouse(display_long)|uniprotkb:Ipo5(gene name)|psi-mi:Ipo5(display_short)|uniprotkb:Ranbp5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR040928|interpro:IPR040122|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR041389 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6mqeNZ0FdCacBeh/ibNMpsjWIL410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A6ZI44 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283485|ensembl:ENSMUSP00000084846 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a6zi44_mouse(display_long)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001170778.1|refseq:XP_006507272.1|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000087566(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035094"(response to nicotine)|go:"GO:0043627"(response to estrogen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:QfjcGwfzA6vJ+Ip6oyWZf4ZCtQM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TS44 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283636 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3ts44_mouse(display_long)|uniprotkb:Psma1(gene name)|psi-mi:Psma1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036095.1|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR035144|mint:Q3TS44 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:5AV1kxiJdOzf5jh1YRmUL94hQwk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q80UU9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1634859|ensembl:ENSMUSP00000056643 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pgrc2_mouse(display_long)|uniprotkb:Pgrmc2(gene name)|psi-mi:Pgrmc2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_081834.1|ensembl:ENSMUSG00000049940(gene)|ensembl:ENSMUST00000058578(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|reactome:R-MMU-8980692|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:KIn48KpS0Z3E1uqRAIbFZVL/nnc10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P70168 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-540580|uniprotkb:Q62117|uniprotkb:Q6GTI5|ensembl:ENSMUSP00000001479 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:imb1_mouse(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:SCG(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Impnb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032405.3|ensembl:ENSMUSG00000001440(gene)|ensembl:ENSMUST00000001479(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|reactome:R-MMU-2995383|reactome:R-MMU-6798695|reactome:R-MMU-909733|reactome:R-MMU-1655829|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:P70168|rcsb pdb:1GCJ|rcsb pdb:1UKL|go:"GO:0019894"(kinesin binding)|reactome:R-MMU-140342|dip:DIP-33404N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:rYDCcZYUZp8TbcpyJE7pfz5+bvo10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P62204 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P28658 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q542D9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284037 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q542d9_mouse(display_long)|uniprotkb:Tfrc(gene name)|psi-mi:Tfrc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036757|interpro:IPR037324|refseq:NP_035768.1|interpro:IPR007484(Peptidase M28)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|refseq:XP_006522062.1|interpro:IPR029513|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR039373 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VFnVdK5loK3683nCBW7vxIe7M6Y10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P59913 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282915|ensembl:ENSMUSP00000059261 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pcmd1_mouse(display_long)|uniprotkb:Pcmtd1(gene name)|psi-mi:Pcmtd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_898849.1|ensembl:ENSMUSG00000051285(gene)|ensembl:ENSMUST00000061280(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HCK1zY5gjRef1W5wg+vWdKvmt9g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O35737 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299747|ensembl:ENSMUSP00000070503|ensembl:ENSMUSP00000104770 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hnrh1_mouse(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Hnrph(gene name synonym)|uniprotkb:Hnrph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000007850(gene)|ensembl:ENSMUST00000069304(transcript)|ensembl:ENSMUST00000109142(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:O35737|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:NP_067485.1|refseq:XP_017170179.1|refseq:XP_017170180.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nBSCiXDDfkwqslFAXPXlDzC+5e410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q64512 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284057|uniprotkb:Q61494|uniprotkb:Q62135|uniprotkb:Q64499 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ptn13_mouse(display_long)|uniprotkb:Ptpn13(gene name)|psi-mi:Ptpn13(display_short)|uniprotkb:Ptp14(gene name synonym)|uniprotkb:PTP36(gene name synonym)|uniprotkb:Protein tyrosine phosphatase DPZPTP(gene name synonym)|uniprotkb:Protein tyrosine phosphatase PTP-BL(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase RIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR035963|interpro:IPR036034|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|rcsb pdb:6GBD|rcsb pdb:6GBE|refseq:NP_035334.2|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011019(KIND)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|rcsb pdb:1GM1|rcsb pdb:1OZI|rcsb pdb:1VJ6|interpro:IPR029021|interpro:IPR029071|go:"GO:0001650"(fibrillar center)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0030496"(midbody)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|reactome:R-MMU-1660499|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:cPfYanrHD/RnZ+Akt306Ua1CQxI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q80T84 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283393 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q80t84_mouse(display_long)|uniprotkb:Mroh1(gene name)|psi-mi:Mroh1(display_short)|uniprotkb:Heatr7a(gene name synonym)|uniprotkb:mKIAA1833(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nX2FRMe6J+ILVjw/r+kYcJDXtoM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q545G0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283248 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q545g0_mouse(display_long)|uniprotkb:Psmb3(gene name)|psi-mi:Psmb3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036101.1|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR033811 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:LLhBgxXML1O4gyh9co1+55VyPM410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q5HZH8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283652 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q5hzh8_mouse(display_long)|uniprotkb:Mad2l1(gene name)|psi-mi:Mad2l1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036570|refseq:NP_062372.2|interpro:IPR003511(DNA-binding HORMA)|refseq:XP_006506469.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:T2SuApPGRno6LWCTPwVqAvQEVZQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2A5R2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283806|ensembl:ENSMUSP00000096677 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:big2_mouse(display_long)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Big2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001078964.1|ensembl:ENSMUSG00000074582(gene)|ensembl:ENSMUST00000099078(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:kHCteybcE9xmumNV1/XeKctG6sA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 intact:EBI-4283403 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 - psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2bfa6_mouse(display_short)|psi-mi:EBI-4283403(display_long)|uniprotkb:Naglu(gene name)|psi-mi:Naglu(display_short)|uniprotkb:RP23-440M18.1-001(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 uniprotkb:A2BFA6(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Wk3d0MOX4aDXePOotmzQPwoS8eQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68181 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400685|uniprotkb:P05206|uniprotkb:Q3TQH5|uniprotkb:Q3UDD0|uniprotkb:Q3UTH5|ensembl:ENSMUSP00000099573 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:kapcb_mouse(display_long)|uniprotkb:Prkacb(gene name)|psi-mi:Prkacb(display_short)|uniprotkb:Pkacb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001157670.1|refseq:NP_001157671.1|refseq:NP_001157672.1|refseq:NP_035230.1|ensembl:ENSMUSG00000005034(gene)|ensembl:ENSMUST00000102515(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P68181|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8963896|reactome:R-MMU-983231 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:9278c8xZsjU90+vryXpzUc0y/G010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9WTI7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U3Z4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283523 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u3z4_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:Gcn1l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR016024(Armadillo-type fold)|interpro:IPR033173|go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Zu8cbDTfjKZt28FQLO+nWCcNZAA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q61699 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772450|uniprotkb:Q3TNS2|uniprotkb:Q3UIY8|uniprotkb:Q62578|uniprotkb:Q62579|uniprotkb:Q6A0A5|uniprotkb:Q8C430|uniprotkb:Q8VCW6|ensembl:ENSMUSP00000144413|ensembl:ENSMUSP00000144654 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hs105_mouse(display_long)|uniprotkb:Heat shock-related 100 kDa protein E7I(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:42 degrees C-HSP(gene name synonym)|uniprotkb:Hsph1(gene name)|psi-mi:Hsph1(display_short)|uniprotkb:Hsp105(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Kiaa0201(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_038587.2|refseq:NP_001334463.1|dip:DIP-32354N|ensembl:ENSMUSG00000029657(gene)|ensembl:ENSMUST00000201452(transcript)|ensembl:ENSMUST00000202361(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q61699|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pZByRgd8f5XdmB138rYxEMrwkRY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99KN2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283601|uniprotkb:Q9DCZ7|ensembl:ENSMUSP00000003759 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ciao1_mouse(display_long)|uniprotkb:Ciao1(gene name)|psi-mi:Ciao1(display_short)|uniprotkb:Wdr39(gene name synonym)|uniprotkb:WD repeat-containing protein 39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_079572.2|ensembl:ENSMUSG00000003662(gene)|ensembl:ENSMUST00000003759(transcript)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:Q99KN2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:zIBtbbwc4hWRw+uGBN5090nQ1Nk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99P31 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283763|uniprotkb:Q9CYV8|ensembl:ENSMUSP00000078886 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hpbp1_mouse(display_long)|uniprotkb:Hspbp1(gene name)|psi-mi:Hspbp1(display_short)|uniprotkb:Hspbp(gene name synonym)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_077134.1|refseq:XP_006540351.1|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q99P31|ensembl:ENSMUSG00000063802(gene)|ensembl:ENSMUST00000079970(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0031398"(positive regulation of protein ubiquitination) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nMkL4DXY9VfPIRdEesUfaGQ7ofY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9QUM9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991694|uniprotkb:Q0VGS3|uniprotkb:Q3TT07|uniprotkb:Q3U6Y2|ensembl:ENSMUSP00000021412 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa6_mouse(display_long)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:Psma6(gene name)|psi-mi:Psma6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036098.1|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:Q9QUM9|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|ensembl:ENSMUSG00000021024(gene)|ensembl:ENSMUST00000021412(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|reactome:R-MMU-69481|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VgUJoxRfxHDdUz0LNg/kcEY95a010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O55234 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991760|uniprotkb:Q9R1P2|uniprotkb:Q3UZI1|uniprotkb:Q91X53|uniprotkb:Q9CWR4|ensembl:ENSMUSP00000022803 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb5_mouse(display_long)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Psmb5(gene name)|psi-mi:Psmb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000022193(gene)|ensembl:ENSMUST00000022803(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0005813"(centrosome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:O55234|rcsb pdb:3UNB|rcsb pdb:3UNE|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-195253|reactome:R-MMU-68949|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-69017|reactome:R-MMU-8948751|reactome:R-MMU-69481|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|refseq:NP_035316.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fYhsgekPQbsqZwwxI3ORdi9Sn0k10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q03265 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68181 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400685|uniprotkb:P05206|uniprotkb:Q3TQH5|uniprotkb:Q3UDD0|uniprotkb:Q3UTH5|ensembl:ENSMUSP00000099573 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:kapcb_mouse(display_long)|uniprotkb:Prkacb(gene name)|psi-mi:Prkacb(display_short)|uniprotkb:Pkacb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001157670.1|refseq:NP_001157671.1|refseq:NP_001157672.1|refseq:NP_035230.1|ensembl:ENSMUSG00000005034(gene)|ensembl:ENSMUST00000102515(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P68181|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8963896|reactome:R-MMU-983231 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:9278c8xZsjU90+vryXpzUc0y/G010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9Z2X1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U2G2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284094|ensembl:ENSMUSP00000020630 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u2g2_mouse(display_long)|uniprotkb:Hspa4(gene name)|psi-mi:Hspa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032326.3|ensembl:ENSMUSG00000020361(gene)|ensembl:ENSMUST00000020630(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:hjeg4KTmOF9Jzi8+sGvPTU7w35g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P58252 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773856|uniprotkb:Q544E4|ensembl:ENSMUSP00000046101 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ef2_mouse(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_031933.1|ensembl:ENSMUSG00000034994(gene)|ensembl:ENSMUST00000047864(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P58252|reactome:R-MMU-156902|reactome:R-MMU-5358493|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:910/vo3IRjcncyPD4f43dPtS83o10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P33610 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P60335 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-309059|ensembl:ENSMUSP00000054863 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O55143 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-770763|uniprotkb:Q9R2A9|uniprotkb:Q9WUT5|ensembl:ENSMUSP00000031423|ensembl:ENSMUSP00000135935 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:at2a2_mouse(display_long)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)|uniprotkb:Atp2a2(gene name)|psi-mi:Atp2a2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001103610.1|refseq:NP_033852.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O55143|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000029467(gene)|ensembl:ENSMUST00000031423(transcript)|ensembl:ENSMUST00000179939(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:LJG8hpHG2pO9ePikEKYbhsuCeRI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A5JUZ1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280663 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TKK8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283384 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tkk8_mouse(display_long)|uniprotkb:Hook2(gene name)|psi-mi:Hook2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR008636(HOOK)|refseq:NP_001161463.1|interpro:IPR036872|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR043936 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:h6++ZvBm7my4TKBdJPqPLhAoepQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q7TN75 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283936|uniprotkb:Q9EQ11 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:peg10_mouse(display_long)|uniprotkb:Peg10(gene name)|psi-mi:Peg10(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Mart2(gene name synonym)|uniprotkb:Mar2(gene name synonym)|uniprotkb:Mef3l1(gene name synonym)|uniprotkb:Rgag3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001035701.1|refseq:NP_570947.2|interpro:IPR021109|interpro:IPR005162(Retrotransposon gag protein)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR032567|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Ay55/wBT5JiR1ULjKC9cEymVYss10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2AM57 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280712|ensembl:ENSMUSP00000030029 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1J4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2552275|ensembl:ENSMUSP00000025649|uniprotkb:Q99LV3|uniprotkb:Q9QYK0|uniprotkb:Q3U8G3|uniprotkb:Q9WV39|uniprotkb:Q3UJC4|uniprotkb:Q3U4D0 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ddb1_mouse(display_long)|uniprotkb:Ddb1(gene name)|psi-mi:Ddb1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000024740(gene)|ensembl:ENSMUST00000025649(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_056550.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|mint:Q3U1J4|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|go:"GO:0005654"(nucleoplasm)|dip:DIP-56812N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dvNwCrG9In1FV2j/+PrsSMvqFnk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P20664 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-848742|ensembl:ENSMUSP00000026461 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1ot482OC79gyXLWhgZIAppJwPzw10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6P1Y9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283275|ensembl:ENSMUSP00000109121 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6p1y9_mouse(display_long)|uniprotkb:Exoc1(gene name)|psi-mi:Exoc1(display_short)|uniprotkb:Sec3l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_081546.1|ensembl:ENSMUSG00000036435(gene)|ensembl:ENSMUST00000113493(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q6P1Y9|refseq:NP_001276699.1|refseq:NP_001276700.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:2HAmUJdq4vLcizqFoiFx9IwMC3010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q71LX8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2657945 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q91YN9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99JY0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299517|ensembl:ENSMUSP00000026841|ensembl:ENSMUSP00000110431|ensembl:ENSMUSP00000110434|uniprotkb:Q3TEH9|uniprotkb:Q8BJI5|uniprotkb:Q8BJM0|uniprotkb:Q8BK52 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:echb_mouse(display_long)|uniprotkb:Hadhb(gene name)|psi-mi:Hadhb(display_short)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000059447(gene)|ensembl:ENSMUST00000026841(transcript)|ensembl:ENSMUST00000114783(transcript)|ensembl:ENSMUST00000114786(transcript)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q99JY0|reactome:R-MMU-1482798|reactome:R-MMU-77285|reactome:R-MMU-77305|reactome:R-MMU-77310|reactome:R-MMU-77346|reactome:R-MMU-77348|reactome:R-MMU-77350|interpro:IPR002155(Thiolase)|refseq:NP_663533.1|refseq:NP_001276727.1|refseq:NP_001276728.1|refseq:XP_017176317.1|refseq:XP_017176318.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:XpJTZFG2xL1ouAgOyU562mqD64I10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q4G0B8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4284006 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q4g0b8_mouse(display_long)|uniprotkb:Ipo9(gene name)|psi-mi:Ipo9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR016024(Armadillo-type fold)|interpro:IPR001494(Importin-beta, N-terminal)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:j2cqUUoc4afIkOHfcx4dDYbDT+A10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9EPL8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2550269|ensembl:ENSMUSP00000081782|uniprotkb:Q7TN09|uniprotkb:Q7TQ63|uniprotkb:Q8BKD8|uniprotkb:Q8BYI0 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ipo7_mouse(display_long)|uniprotkb:Ipo7(gene name)|psi-mi:Ipo7(display_short)|uniprotkb:Ranbp7(gene name synonym)|uniprotkb:Ran-binding protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000066232(gene)|ensembl:ENSMUST00000084731(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9EPL8|refseq:NP_852658.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:YOGtbOzeE6Oq5T0J42GWW7fH9H010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TL95 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283458 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tl95_mouse(display_long)|uniprotkb:Psma4(gene name)|psi-mi:Psma4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR034647 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:U1I1Q7r0z1Fob9MGc8MTFRkmA1Q10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P62204 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q5SSW2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283842|uniprotkb:Q3TER7|uniprotkb:Q3V2B7|uniprotkb:Q6ZQJ7|uniprotkb:Q7TMY9|uniprotkb:Q8K0K0|uniprotkb:Q99KM2|uniprotkb:Q9ESY1|ensembl:ENSMUSP00000045460|uniprotkb:C4IXU5 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psme4_mouse(display_long)|uniprotkb:Psme4(gene name)|psi-mi:Psme4(display_short)|uniprotkb:Kiaa0077(gene name synonym)|uniprotkb:Proteasome activator PA200(gene name synonym)|uniprotkb:Protein TEMO(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_598774.2|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000040850(gene)|ensembl:ENSMUST00000041231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032430|interpro:IPR035309|mint:Q5SSW2|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:LQiV+yvUQhD6KkKZGnAHj93ktyo10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TS44 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283636 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3ts44_mouse(display_long)|uniprotkb:Psma1(gene name)|psi-mi:Psma1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036095.1|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR035144|mint:Q3TS44 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:5AV1kxiJdOzf5jh1YRmUL94hQwk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UM23 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281076 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BFR5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O35382 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772648|ensembl:ENSMUSP00000051965 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:exoc4_mouse(display_long)|uniprotkb:Exocyst complex component Sec8(gene name synonym)|uniprotkb:Exoc4(gene name)|psi-mi:Exoc4(display_short)|uniprotkb:Sec8(gene name synonym)|uniprotkb:Sec8l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_033174.2|dip:DIP-32368N|ensembl:ENSMUSG00000029763(gene)|ensembl:ENSMUST00000052266(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043209"(myelin sheath)|go:"GO:0044091"(membrane biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:O35382|reactome:R-MMU-264876|reactome:R-MMU-5620916 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:kgplLpzVE6TdHg877TyXAlCXb7g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P17710 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773368|uniprotkb:E9PXQ3|uniprotkb:Q61659|uniprotkb:Q64476|uniprotkb:Q64479 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hxk1_mouse(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Hexokinase, tumor isozyme(gene name synonym)|uniprotkb:Hk1(gene name)|psi-mi:Hk1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR019807|interpro:IPR022672|refseq:XP_006513305.1|refseq:XP_006513306.1|refseq:XP_006513307.1|refseq:XP_006513308.1|interpro:IPR043129|mint:P17710|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|reactome:R-MMU-70171 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:x4T9LnTLPxq69q+uvfTwLT8gCn410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P99026 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991752|uniprotkb:Q3THC0|uniprotkb:Q3THI3|uniprotkb:Q3U0S0|uniprotkb:Q3UVQ4|uniprotkb:Q62008|uniprotkb:Q8BK27|uniprotkb:Q91VV7|ensembl:ENSMUSP00000005923 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb4_mouse(display_long)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:Psmb4(gene name)|psi-mi:Psmb4(display_short)|uniprotkb:Lmp3(gene name synonym)|uniprotkb:Low molecular mass protein 3(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032971.2|ensembl:ENSMUSG00000005779(gene)|ensembl:ENSMUST00000005923(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P99026|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-4608870|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|dip:DIP-35152N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:jTLU7QS1B0YP4ZedlzxXtnhioRQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63017 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9D071 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283533|uniprotkb:Q925N8|uniprotkb:Q9CWX3|uniprotkb:F8WHX3|ensembl:ENSMUSP00000130900 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:mms19_mouse(display_long)|uniprotkb:Mms19(gene name)|psi-mi:Mms19(display_short)|uniprotkb:Mms19l(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_082428.1|ensembl:ENSMUSG00000025159(gene)|ensembl:ENSMUST00000171561(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|rcsb pdb:6TBL|rcsb pdb:6TC0 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:S24j+ddJAniA1XEtuEoZvrT6K7s10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:E9Q557 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-688046|ensembl:ENSMUSP00000115062 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)" figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63037 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P14602 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299023|ensembl:ENSMUSP00000005077 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q5HZH8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283652 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q5hzh8_mouse(display_long)|uniprotkb:Mad2l1(gene name)|psi-mi:Mad2l1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036570|refseq:NP_062372.2|interpro:IPR003511(DNA-binding HORMA)|refseq:XP_006506469.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:T2SuApPGRno6LWCTPwVqAvQEVZQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BGS1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283324|uniprotkb:Q3TJG0|uniprotkb:Q69ZG8|uniprotkb:Q8BSC9|uniprotkb:Q99KZ8|ensembl:ENSMUSP00000058966 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:e41l5_mouse(display_long)|uniprotkb:Epb4.1l5(gene name synonym)|uniprotkb:Kiaa1548(gene name synonym)|uniprotkb:Epb41l5(gene name)|psi-mi:Epb41l5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0001756"(somitogenesis)|refseq:NP_001106887.1|refseq:NP_663481.2|refseq:XP_006529460.1|refseq:XP_006529461.1|refseq:XP_006529463.1|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0048319"(axial mesoderm morphogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|ensembl:ENSMUSG00000026383(gene)|ensembl:ENSMUST00000052404(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|interpro:IPR030694|mint:Q8BGS1|reactome:R-MMU-6794361|interpro:IPR035963 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pt6yMNx5+txA950Eal6TthTO5sM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O70435 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991671|ensembl:ENSMUSP00000125548 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa3_mouse(display_long)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:Proteasome subunit K(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Psma3(gene name)|psi-mi:Psma3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035314.3|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|interpro:IPR023332|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|interpro:IPR029055|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|interpro:IPR037555|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|ensembl:ENSMUSG00000060073(gene)|ensembl:ENSMUST00000160027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|refseq:XP_017170485.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:NgV6tyZ0v25UGZ5FkGZNNLMJVjQ10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TPX4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-775555|uniprotkb:Q80VK3|ensembl:ENSMUSP00000125434 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:exoc5_mouse(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:Exoc5(gene name)|psi-mi:Exoc5(display_short)|uniprotkb:Sec10l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_997097.1|ensembl:ENSMUSG00000061244(gene)|ensembl:ENSMUST00000162175(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|reactome:R-MMU-264876|reactome:R-MMU-5620916 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:lLxyXBlor+hHByz1xwPbJBRic1g10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68369 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q99MW3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283683|ensembl:ENSMUSP00000043718 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:pral1_mouse(display_long)|uniprotkb:Pramel1(gene name)|psi-mi:Pramel1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_113554.1|ensembl:ENSMUSG00000041805(gene)|ensembl:ENSMUST00000037419(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031514"(motile cilium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR026271|interpro:IPR032675 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fuP3Qw5yyHw+wYeuKyVQb8yOuuo10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3TJA9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283904 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3tja9_mouse(display_long)|uniprotkb:Dnaja3(gene name)|psi-mi:Dnaja3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001128584.1|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR036410|interpro:IPR036869|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:imDckk2w4uXfQciLWUxkieJk2vI10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BFW7 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283284|uniprotkb:Q5U407|uniprotkb:Q8BHI1|uniprotkb:Q8BKI0|uniprotkb:Q8BKN2|uniprotkb:Q8BLF4|uniprotkb:Q8BLG3|uniprotkb:Q8C101|ensembl:ENSMUSP00000036304|ensembl:ENSMUSP00000078005 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:lpp_mouse(display_long)|uniprotkb:Lpp(gene name)|psi-mi:Lpp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001139424.1|refseq:NP_001139426.1|refseq:NP_848780.3|refseq:XP_006522020.1|ensembl:ENSMUSG00000033306(gene)|ensembl:ENSMUST00000078988(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0046872"(metal ion binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028771|mint:Q8BFW7|ensembl:ENSMUST00000038053(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:XAdPnciv19gtS4vVm6mv1bIfOE810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UHQ5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2550458 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3uhq5_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:Gcn1l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|refseq:NP_766307.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1t/G1ybGLV/oHg/3GijS0N8AWjk10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q62425 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BP00 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O35737 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-299747|ensembl:ENSMUSP00000070503|ensembl:ENSMUSP00000104770 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hnrh1_mouse(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Hnrph(gene name synonym)|uniprotkb:Hnrph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000007850(gene)|ensembl:ENSMUST00000069304(transcript)|ensembl:ENSMUST00000109142(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:O35737|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:NP_067485.1|refseq:XP_017170179.1|refseq:XP_017170180.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:nBSCiXDDfkwqslFAXPXlDzC+5e410090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P05213 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q91YN9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8BWT1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:15aWO97WJBNGYD449bAgjVjkgTY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UDN8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283418 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3udn8_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR003649(B-box, C-terminal)|interpro:IPR001487(Bromodomain)|interpro:IPR019786|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VPtUcH9n/fF4qpCKwWPIfuGxEVU10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8C3Y4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283441|uniprotkb:Q6A0B3|ensembl:ENSMUSP00000031366 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:kntc1_mouse(display_long)|uniprotkb:Kntc1(gene name)|psi-mi:Kntc1(display_short)|uniprotkb:Kiaa0166(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001035886.1|ensembl:ENSMUSG00000029414(gene)|ensembl:ENSMUST00000031366(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051301"(cell division)|go:"GO:1990423"(RZZ complex)|interpro:IPR019527|interpro:IPR036322|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:xBlgipnAkXH/5FBM2XmL0K3c3+Q10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68372 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A1E2B8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282145 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a1e2b8_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0005524"(ATP binding)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ZWP3SAChvtexmuiM2xOxCL9ud0U10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A0JNT0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283311 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a0jnt0_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR036770|refseq:NP_001268906.1|refseq:NP_001268907.1|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:FES9DsulJzFGdCImT2oalvQfUok10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3THL2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4283753 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3thl2_mouse(display_long)|uniprotkb:Psma7(gene name)|psi-mi:Psma7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|refseq:NP_001276405.1|interpro:IPR029055|interpro:IPR035190|mint:Q3THL2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:40phN4FYZWAmjdKRst1nqlt9N+U10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68369 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O09061 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991712|uniprotkb:Q62038|uniprotkb:Q62039|ensembl:ENSMUSP00000014913 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb1_mouse(display_long)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)|uniprotkb:Psmb1(gene name)|psi-mi:Psmb1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000014769(gene)|ensembl:ENSMUST00000014913(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|mint:O09061|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-75815|refseq:NP_035315.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:CIHxzlrtwKh+f15z5Uf8Bv4yJ0o10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q71LX8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2657945 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4283417|imex:IM-16529-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-4282065] The protein has been merged with EBI-772469 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4280750] The protein has been merged with EBI-772325 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4282155] The protein has been merged with EBI-991777 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283666] The protein has been merged with EBI-991720 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283777] The protein has been merged with EBI-991788 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4283823] The protein has been merged with EBI-400836 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:945AF4DE041DD89A|rigid:LfOyV9wncCw1vt7QVVEsVzVcJjE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q07968 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284359|uniprotkb:B1AY02|ensembl:ENSMUSP00000027615 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:f13b_mouse(display_long)|uniprotkb:F13b(gene name)|psi-mi:F13b(display_short)|uniprotkb:Cf13b(gene name synonym)|uniprotkb:Protein-glutamine gamma-glutamyltransferase B chain(gene name synonym)|uniprotkb:Transglutaminase B chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_112441.2|ensembl:ENSMUSG00000026368(gene)|ensembl:ENSMUST00000027615(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007596"(blood coagulation)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|reactome:R-MMU-140875 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:aGAlswlZIjLal5OWVbJw/aBjjDY10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P97820 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-644181 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:m4k4_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)|uniprotkb:Map4k4(gene name)|psi-mi:Map4k4(display_short)|uniprotkb:Nik(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_001239129.1|refseq:NP_001239130.1|refseq:NP_001239131.1|refseq:NP_032722.2|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-2559580|go:"GO:0106311"|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|dip:DIP-40973N|mint:P97820 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:laMTX6DrOoTz4D8zxLP5ohzqKyw10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q9CZ62 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-648025|uniprotkb:Q8BL35|ensembl:ENSMUSP00000023270 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:cep97_mouse(display_long)|uniprotkb:Lrriq2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:Cep97(gene name)|psi-mi:Cep97(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_001152836.1|refseq:NP_001152837.1|refseq:NP_001152838.1|refseq:NP_083091.1|ensembl:ENSMUSG00000022604(gene)|ensembl:ENSMUST00000023270(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q9CZ62|reactome:R-MMU-5620912|reactome:R-MMU-9013424 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:DWiMTuw3lDIkq7+vwiCf3HJZZ7k10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P23927 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q3UXG3 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284416 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:q3uxg3_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_001240292.1|refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|interpro:IPR024939|go:"GO:0060072"(large conductance calcium-activated potassium channel activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:P4ULu5rQE6L3+htkI/7vklTpDSc10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P62204 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q8BP00 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P62991 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q3V125 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284340|uniprotkb:Q3TTQ8|ensembl:ENSMUSP00000092964 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:cc110_mouse(display_long)|uniprotkb:Ccdc110(gene name)|psi-mi:Ccdc110(display_short)|uniprotkb:Gm172(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_001028418.1|ensembl:ENSMUSG00000071104(gene)|ensembl:ENSMUST00000095326(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:L6rhyTkDio4VgVAzV+glr6f9OGo10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q6KAP1 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284350 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:q6kap1_mouse(display_long)|uniprotkb:mFLJ00246(gene name)|psi-mi:mFLJ00246(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:5QcSz2O7R6rCJRj9h/BqLDmYnFo10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q3TMW1 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284446|uniprotkb:A0AUL1|uniprotkb:Q3B7Y4|ensembl:ENSMUSP00000077107 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:c102a_mouse(display_long)|uniprotkb:Ccdc102a(gene name)|psi-mi:Ccdc102a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_001028705.2|refseq:XP_011246656.1|ensembl:ENSMUSG00000063605(gene)|ensembl:ENSMUST00000077955(transcript)|go:"GO:0016459"(myosin complex)|interpro:IPR002928(Myosin tail) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:o+1Z3eGR7bGWdpyV/FHp7ijRfAo10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P16125 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-444932|uniprotkb:Q545Y4|ensembl:ENSMUSP00000032373|ensembl:ENSMUSP00000159362 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:ldhb_mouse(display_long)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Ldhb(gene name)|psi-mi:Ldhb(display_short)|uniprotkb:Ldh-2(gene name synonym)|uniprotkb:Ldh2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_032518.1|refseq:NP_001303251.1|ensembl:ENSMUSG00000030246(gene)|ensembl:ENSMUST00000032373(transcript)|ensembl:ENSMUST00000239397(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0051287"(NAD binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P16125|reactome:R-MMU-70268|interpro:IPR001557(L-lactate/malate dehydrogenase)|refseq:NP_001289694.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:jN0wT7b/jHBnWCfV48irZYeGxa410090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q5NCX5 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284398|uniprotkb:Q3U090|uniprotkb:Q5NCX4|uniprotkb:Q69ZA2|uniprotkb:Q8R1V5|ensembl:ENSMUSP00000053235 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:neul4_mouse(display_long)|uniprotkb:Neurl4(gene name)|psi-mi:Neurl4(display_short)|uniprotkb:Kiaa1787(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_001013432.1|refseq:NP_001278047.1|refseq:NP_001278048.1|ensembl:ENSMUSG00000047284(gene)|ensembl:ENSMUST00000061837(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006573(NEUZ)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037962|interpro:IPR043136|mint:Q5NCX5|refseq:XP_017169947.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:ptQRCtQs60MpIBFD5++Vnv69Sfc10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q9R0L6 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284371|uniprotkb:O70287|uniprotkb:Q3URH6|uniprotkb:Q7TMS7|uniprotkb:Q8C9V2|uniprotkb:Q91Y27|uniprotkb:Q91Y28|uniprotkb:Q91Y51|uniprotkb:Q9CRK8|uniprotkb:Q923L0|uniprotkb:Q9CT57|uniprotkb:E9QLK2|ensembl:ENSMUSP00000039709 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:pcm1_mouse(display_long)|uniprotkb:Pcm1(gene name)|psi-mi:Pcm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_076151.2|refseq:XP_006509361.1|ensembl:ENSMUSG00000031592(gene)|ensembl:ENSMUST00000045218(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q9R0L6|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-5620912|reactome:R-MMU-8854518|reactome:R-MMU-380320 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:OT+ZOQY5pqQojMcLCWMIY+6zdl410090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q7TSH4 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q9CPN9 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4281507|ensembl:ENSMUSP00000031931 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:q9cpn9_mouse(display_long)|uniprotkb:2210010C04Rik(gene name)|psi-mi:2210010C04Rik(display_short)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 ensembl:ENSMUSG00000029882(gene)|ensembl:ENSMUST00000031931(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|refseq:NP_075822.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:Zo4iGyJp1bpaflfoVpqcBqS6mm410090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P63017 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P05213 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:O35435 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284503|ensembl:ENSMUSP00000115934 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:pyrd_mouse(display_long)|uniprotkb:Dhodh(gene name)|psi-mi:Dhodh(display_short)|uniprotkb:Dihydroorotate oxidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_064430.1|ensembl:ENSMUSG00000031730(gene)|ensembl:ENSMUST00000123605(transcript)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0010181"(FMN binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0048038"(quinone binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0009220"(pyrimidine ribonucleotide biosynthetic process)|go:"GO:1903576"(response to L-arginine)|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|interpro:IPR005719(Dihydroorotate dehydrogenase, class 2)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR013785(Aldolase-type TIM barrel)|reactome:R-MMU-500753 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:o0PHUUtUpriblPpBHVqes+zhTyk10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:Q02257 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P99024 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6A078 uniprotkb:P19228 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4284550|ensembl:ENSMUSP00000092225 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:casa1_mouse(display_long)|uniprotkb:Csn1s1(gene name)|psi-mi:Csn1s1(display_short)|uniprotkb:Csn1(gene name synonym)|uniprotkb:Csna(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284445|imex:IM-16529-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_031810.1|refseq:NP_001272944.1|refseq:NP_001272945.1|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|interpro:IPR001588(Casein, alpha/beta)|interpro:IPR026999|interpro:IPR031305|reactome:R-MMU-5223345|ensembl:ENSMUSG00000070702(gene)|ensembl:ENSMUST00000094641(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:pn5phLyF+1mKkloPqPq1jWz3RN810090 intact-crc:B5595AD8F58D4A47|rigid:HW2L3epU1wGQhD7oDy6Z6G4VhGQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q61937 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-626362|ensembl:ENSMUSP00000075067 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:npm_mouse(display_long)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)|uniprotkb:Npm1(gene name)|psi-mi:Npm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051054"(positive regulation of DNA metabolic process)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097421"(liver regeneration)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:Q61937|rcsb pdb:4N8M|reactome:R-MMU-3899300|reactome:R-MMU-606279|reactome:R-MMU-6804115|reactome:R-MMU-8869496|ensembl:ENSMUSG00000057113(gene)|ensembl:ENSMUST00000075641(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0002039"(p53 binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|refseq:NP_032748.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:i/cYJMIvj0nTZoQNh4thiojopbA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R4Z4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285440|uniprotkb:Q9QZW1|ensembl:ENSMUSP00000112915|ensembl:ENSMUSP00000127419|uniprotkb:G5E907 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:etv3_mouse(display_long)|uniprotkb:Etv3(gene name)|psi-mi:Etv3(display_short)|uniprotkb:Mets(gene name synonym)|uniprotkb:Pe1(gene name synonym)|uniprotkb:ETS domain transcriptional repressor PE1(gene name synonym)|uniprotkb:Mitogenic Ets transcriptional suppressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001076787.1|refseq:NP_036181.3|ensembl:ENSMUST00000170036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR032929|interpro:IPR036388|interpro:IPR036390|ensembl:ENSMUSG00000003382(gene)|ensembl:ENSMUST00000119109(transcript)|refseq:NP_001273773.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:InJJ+NqNYr5DBhhJJzg+y1DVnvg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8JZQ9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286513|uniprotkb:Q922K2|ensembl:ENSMUSP00000098076 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:eif3b_mouse(display_long)|uniprotkb:Eif3b(gene name)|psi-mi:Eif3b(display_short)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:Eif3s9(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_598677.1|ensembl:ENSMUSG00000056076(gene)|ensembl:ENSMUST00000100507(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:Q8JZQ9|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Mi9GReY+V693P20QOUsHizsl5DY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:A2AH22 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284600|uniprotkb:Q3UF70|uniprotkb:Q6ZPJ1|uniprotkb:Q8BJJ8|uniprotkb:Q8BYW8|uniprotkb:A2AH21|uniprotkb:A2AH24|uniprotkb:Q3U239|uniprotkb:Q3TF60|ensembl:ENSMUSP00000049258 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:amra1_mouse(display_long)|uniprotkb:Ambra1(gene name)|psi-mi:Ambra1(display_short)|uniprotkb:Kiaa1736(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001074223.1|refseq:NP_766257.3|refseq:XP_006499316.1|ensembl:ENSMUSG00000040506(gene)|ensembl:ENSMUST00000045705(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0021915"(neural tube development)|go:"GO:0030154"(cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:A2AH22|reactome:R-MMU-1632852|go:"GO:0051020"(GTPase binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:fKzPYvVBztq0TCsNtvLQyHU5Z8U10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q68FD5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-769168|ensembl:ENSMUSP00000099475 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:clh1_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001003908.1|dip:DIP-31947N|ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000103186(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q68FD5|rcsb pdb:5ODS|reactome:R-MMU-177504|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0032051"(clathrin light chain binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:iHg/TOG2rWePqtsEmuc/szn/chI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9WTX8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285225|uniprotkb:Q9WTX9|ensembl:ENSMUSP00000031534 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:md1l1_mouse(display_long)|uniprotkb:Mad1l1(gene name)|psi-mi:Mad1l1(display_short)|uniprotkb:Mad1(gene name synonym)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034882.2|ensembl:ENSMUSG00000029554(gene)|ensembl:ENSMUST00000031534(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9WTX8|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|go:"GO:0048538"(thymus development)|refseq:XP_006504714.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:uJ8x1UBlL+30Ss2DFiEhiGLoNfo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O54825 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284563|uniprotkb:Q3THF4|uniprotkb:Q3UPY9|uniprotkb:Q8VD68|ensembl:ENSMUSP00000024783 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:byst_mouse(display_long)|uniprotkb:Bysl(gene name)|psi-mi:Bysl(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_058555.3|go:"GO:0005737"(cytoplasm)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007955(Bystin)|reactome:R-MMU-6791226|ensembl:ENSMUSG00000023988(gene)|ensembl:ENSMUST00000024783(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001825"(blastocyst formation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:JlkD0p3MBqstE6KH1Uicqai7Lo010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q99K51 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284839|uniprotkb:B1AX56|uniprotkb:Q3TUZ5|ensembl:ENSMUSP00000033547|ensembl:ENSMUSP00000109691|ensembl:ENSMUSP00000109693 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:plst_mouse(display_long)|uniprotkb:Pls3(gene name)|psi-mi:Pls3(display_short)|uniprotkb:T-plastin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001159925.1|refseq:NP_001159926.1|refseq:NP_663604.1|ensembl:ENSMUSG00000016382(gene)|ensembl:ENSMUST00000033547(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:Q99K51|interpro:IPR002048(Calcium-binding EF-hand)|ensembl:ENSMUST00000114059(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|ensembl:ENSMUST00000114057(transcript)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098699"(structural constituent of presynaptic actin cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:OG0fV5yrgxepz7CwEtWLxnYFAjo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3U1J4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2552275|ensembl:ENSMUSP00000025649|uniprotkb:Q99LV3|uniprotkb:Q9QYK0|uniprotkb:Q3U8G3|uniprotkb:Q9WV39|uniprotkb:Q3UJC4|uniprotkb:Q3U4D0 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ddb1_mouse(display_long)|uniprotkb:Ddb1(gene name)|psi-mi:Ddb1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000024740(gene)|ensembl:ENSMUST00000025649(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_056550.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|mint:Q3U1J4|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|go:"GO:0005654"(nucleoplasm)|dip:DIP-56812N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:dvNwCrG9In1FV2j/+PrsSMvqFnk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R349 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2553692|uniprotkb:Q9CYX9|ensembl:ENSMUSP00000047950 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cdc16_mouse(display_long)|uniprotkb:Anapc6(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)|uniprotkb:Cdc16(gene name)|psi-mi:Cdc16(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0072686"(mitotic spindle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q8R349|reactome:R-MMU-141430|reactome:R-MMU-174048|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-176407|reactome:R-MMU-176408|reactome:R-MMU-176409|reactome:R-MMU-176412|reactome:R-MMU-179409|reactome:R-MMU-2467813|reactome:R-MMU-2559582|reactome:R-MMU-69017|reactome:R-MMU-983168|ensembl:ENSMUSG00000038416(gene)|ensembl:ENSMUST00000043962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|refseq:NP_081552.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:oDF+b59UMuwX8+AfM77CrXaLilg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q01853 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-80597|ensembl:ENSMUSP00000030164|uniprotkb:Q3TFH9|uniprotkb:Q3TIM2|uniprotkb:Q3TXN9|uniprotkb:Q6PI18|uniprotkb:Q8BSR6|uniprotkb:Q8CEG4 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tera_mouse(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:Q01853|rcsb pdb:1E32|rcsb pdb:1R7R|rcsb pdb:1S3S|rcsb pdb:2PJH|rcsb pdb:3CF0|rcsb pdb:3CF1|rcsb pdb:3CF2|rcsb pdb:3CF3|reactome:R-MMU-110320|reactome:R-MMU-3371511|reactome:R-MMU-382556|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5689877|reactome:R-MMU-5689896|reactome:R-MMU-6798695|reactome:R-MMU-8876725|reactome:R-MMU-9013407|ensembl:ENSMUSG00000028452(gene)|ensembl:ENSMUST00000030164(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_033529.3|dip:DIP-29796N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CXW4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1548890|uniprotkb:Q3TPE3|uniprotkb:Q6ZWY0|ensembl:ENSMUSP00000099595 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl11_mouse(display_long)|uniprotkb:Rpl11(gene name)|psi-mi:Rpl11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080195.1|ensembl:ENSMUSG00000059291(gene)|ensembl:ENSMUST00000102536(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045202"(synapse)|go:"GO:0050821"(protein stabilization)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:Q9CXW4|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D1M0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285415|uniprotkb:Q99M12|uniprotkb:Q9D712|ensembl:ENSMUSP00000032440 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:sec13_mouse(display_long)|uniprotkb:Sec13(gene name)|psi-mi:Sec13(display_short)|uniprotkb:Sec13l1(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_077168.2|ensembl:ENSMUSG00000030298(gene)|ensembl:ENSMUST00000032440(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037363|interpro:IPR037596|mint:Q9D1M0|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-204005|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9639288|reactome:R-MMU-9648025|reactome:R-MMU-983170|interpro:IPR036322 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:40KHYuvc/jVIxhLJTKivv2NRm7I10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q02257 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6P5H2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2899462|ensembl:ENSMUSP00000088493|uniprotkb:A1E2I2|uniprotkb:Q80X00|uniprotkb:Q8BPH7|uniprotkb:Q9CV43|uniprotkb:Q9R0C4 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nest_mouse(display_long)|uniprotkb:Nes(gene name)|psi-mi:Nes(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUST00000090973(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030844"(positive regulation of intermediate filament depolymerization)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048858"(cell projection morphogenesis)|ensembl:ENSMUSG00000004891(gene)|go:"GO:0072089"(stem cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR018039|interpro:IPR031211|interpro:IPR039008|refseq:NP_057910.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:c9UQwTSScUEP6n41WzoQiEzEyN410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P05063 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-444845|uniprotkb:Q64011|uniprotkb:Q8CA91|uniprotkb:Q99K96|uniprotkb:Q9DBA4|uniprotkb:Q9JK32|ensembl:ENSMUSP00000017534|ensembl:ENSMUSP00000099536 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:aldoc_mouse(display_long)|uniprotkb:Brain-type aldolase(gene name synonym)|uniprotkb:Aldolase 3(gene name synonym)|uniprotkb:Zebrin II(gene name synonym)|uniprotkb:Scrapie-responsive protein 2(gene name synonym)|uniprotkb:Aldoc(gene name)|psi-mi:Aldoc(display_short)|uniprotkb:Aldo3(gene name synonym)|uniprotkb:Scrg2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033787.2|go:"GO:0030424"(axon)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUST00000017534(transcript)|ensembl:ENSMUST00000102478(transcript)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|mint:P05063|reactome:R-MMU-6798695|reactome:R-MMU-70171|go:"GO:0005829"(cytosol)|reactome:R-MMU-70263|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007568"(aging)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|refseq:NP_001290352.1|ensembl:ENSMUSG00000017390(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:MFpDc0rZbQY47QNygDUe2T6XIYU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91VC3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2552399|ensembl:ENSMUSP00000026667|uniprotkb:Q3UD29|uniprotkb:Q3TEZ8|uniprotkb:B2RY38|uniprotkb:Q8BVY3 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:if4a3_mouse(display_long)|uniprotkb:Eif4a3(gene name)|psi-mi:Eif4a3(display_short)|uniprotkb:Ddx48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 reactome:R-MMU-975957|ensembl:ENSMUSG00000025580(gene)|ensembl:ENSMUST00000026667(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|refseq:NP_619610.1|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q91VC3|reactome:R-MMU-1169408|reactome:R-MMU-159236|reactome:R-MMU-429947|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:6jjMHbLWWbe2j3Qv+g8b/PbY7Ps10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P60710 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8C3I8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-644392|uniprotkb:Q9JJF4|ensembl:ENSMUSP00000023213 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hgh1_mouse(display_long)|uniprotkb:Hgh1(gene name)|psi-mi:Hgh1(display_short)|uniprotkb:Brp16(gene name synonym)|uniprotkb:Fam203a(gene name synonym)|uniprotkb:MNCb-5873(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_067530.2|ensembl:ENSMUSG00000022554(gene)|ensembl:ENSMUST00000023213(transcript)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:/cIz6zUzGXE6w9k0tllMzCrxkWU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q922F4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2310445|ensembl:ENSMUSP00000001513 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tbb6_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080749.2|ensembl:ENSMUSG00000001473(gene)|ensembl:ENSMUST00000001513(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q922F4|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BMS1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299595|ensembl:ENSMUSP00000120976|intact:EBI-773355|uniprotkb:Q5U5Y5|uniprotkb:Q3TCY3|uniprotkb:Q8QZU4 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:echa_mouse(display_long)|uniprotkb:Hadha(gene name)|psi-mi:Hadha(display_short)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000025745(gene)|ensembl:ENSMUST00000156859(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|go:"GO:0042493"|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:Q8BMS1|reactome:R-MMU-1482798|reactome:R-MMU-77285|reactome:R-MMU-77305|reactome:R-MMU-77310|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|reactome:R-MMU-77346|reactome:R-MMU-77348|reactome:R-MMU-77350|go:"GO:0051287"(NAD binding)|refseq:NP_849209.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:xOA1ht6+a9ZSKRvLr0d9U2uPW2s10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P63037 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9QZ83 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1183650 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P59240 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q80TR8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285919|uniprotkb:Q3UXD5|uniprotkb:Q6P1E2|uniprotkb:Q8CDY3|ensembl:ENSMUSP00000060025 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dcaf1_mouse(display_long)|uniprotkb:Dcaf1(gene name)|psi-mi:Dcaf1(display_short)|uniprotkb:Kiaa0800(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:Vprbp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001015507.1|ensembl:ENSMUSG00000040325(gene)|ensembl:ENSMUST00000055009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|reactome:R-MMU-983168|refseq:XP_006511818.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:jD8ln64I0aDM46a1ga3PsXRZyzw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P47955 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285869|ensembl:ENSMUSP00000008036 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rla1_mouse(display_long)|uniprotkb:Rplp1(gene name)|psi-mi:Rplp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_061341.1|ensembl:ENSMUSG00000007892(gene)|ensembl:ENSMUST00000008036(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006417"(regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P47955|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:N2OLAKNWchEjCGAktx1nKMLHLuc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9DBR0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285802|uniprotkb:Q9R0L8|ensembl:ENSMUSP00000002699 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:akap8_mouse(display_long)|uniprotkb:Akap8(gene name)|psi-mi:Akap8(display_short)|uniprotkb:Akap95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000024045(gene)|ensembl:ENSMUST00000002699(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9DBR0|refseq:NP_062748.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:CboiIO6b/r8YM0jLmJbCdzg5S3U10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9DCL9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-911998|uniprotkb:Q9CQ38|ensembl:ENSMUSP00000031160|ensembl:ENSMUSP00000112879|ensembl:ENSMUSP00000113483 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pur6_mouse(display_long)|uniprotkb:Paics(gene name)|psi-mi:Paics(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080215.1|refseq:XP_006535243.1|refseq:XP_006535244.1|refseq:XP_006535245.1|refseq:XP_006535246.1|ensembl:ENSMUSG00000029247(gene)|ensembl:ENSMUST00000031160(transcript)|ensembl:ENSMUST00000117536(transcript)|ensembl:ENSMUST00000120912(transcript)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-MMU-73817 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:pW5pxBgncsKiZoqi6LQJOGCJ0xc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6P5D4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-647072|uniprotkb:Q6A030|ensembl:ENSMUSP00000038674|ensembl:ENSMUSP00000112602 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cp135_mouse(display_long)|uniprotkb:Centrosomal protein 4(gene name synonym)|uniprotkb:Cep135(gene name)|psi-mi:Cep135(display_short)|uniprotkb:Cep4(gene name synonym)|uniprotkb:Kiaa0635(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_950197.1|refseq:XP_006535086.1|ensembl:ENSMUST00000049060(transcript)|ensembl:ENSMUST00000121979(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR026732|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|ensembl:ENSMUSG00000036403(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:bnLzvANWuZvXXiue5WVyCKUIWkA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q5DTG8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285646 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q5dtg8_mouse(display_long)|uniprotkb:Zfp655(gene name)|psi-mi:Zfp655(display_short)|uniprotkb:mKIAA4222(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:vX05gCFJlFc2nQTfLvcJhoi8XCg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8CGC7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285489|uniprotkb:Q3UFJ2|uniprotkb:Q4VC16|uniprotkb:E9QKC4|ensembl:ENSMUSP00000045841 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:syep_mouse(display_long)|uniprotkb:Eprs(gene name synonym)|uniprotkb:Qprs(gene name synonym)|uniprotkb:Eprs1(gene name)|psi-mi:Eprs1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_084011.1|ensembl:ENSMUSG00000026615(gene)|ensembl:ENSMUST00000046514(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:Q8CGC7|interpro:IPR004046(Glutathione S-transferase, C-terminal) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:uFcCD59N912Lvyf6/OxGsROezcU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q62130 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285377|uniprotkb:G5E8M1|ensembl:ENSMUSP00000095051 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ptn14_mouse(display_long)|uniprotkb:Ptpn14(gene name)|psi-mi:Ptpn14(display_short)|uniprotkb:Protein-tyrosine phosphatase PTP36(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:XP_006497192.1|refseq:XP_006497193.1|refseq:XP_006497194.1|refseq:XP_006497196.1|refseq:NP_033002.2|ensembl:ENSMUSG00000026604(gene)|ensembl:ENSMUST00000097442(transcript)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0046825"(regulation of protein export from nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014392(Protein-tyrosine phosphatase, non-receptor type-14, -21)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|go:"GO:0005737"(cytoplasm)|interpro:IPR029071|interpro:IPR035963|interpro:IPR041782 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qmp5SMyYFHhWdlL3+vOdWC4oBXY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q5F2E8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284577|uniprotkb:Q69ZL2|uniprotkb:Q8JZX2|uniprotkb:Q91VG7|ensembl:ENSMUSP00000017435|ensembl:ENSMUSP00000055470 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:taok1_mouse(display_long)|uniprotkb:Taok1(gene name)|psi-mi:Taok1(display_short)|uniprotkb:Kiaa1361(gene name synonym)|uniprotkb:Thousand and one amino acid protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_659074.2|refseq:XP_011247231.1|refseq:XP_011247232.1|refseq:XP_011247233.1|refseq:XP_006533021.1|refseq:XP_006533022.1|ensembl:ENSMUSG00000017291(gene)|ensembl:ENSMUST00000017435(transcript)|ensembl:ENSMUST00000058496(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031489"(myosin V binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0000165"(MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|interpro:IPR017441(Protein kinase ATP binding, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:kPIRP5vHdhQwx5sNRlhFSYQRnuE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P17751 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-444877|uniprotkb:Q3TJH2|uniprotkb:Q3UC04|uniprotkb:Q3UKG9|uniprotkb:Q64513|uniprotkb:Q9CVF9|uniprotkb:Q9CWE7|ensembl:ENSMUSP00000130858 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tpis_mouse(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Tpi(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033441.2|ensembl:ENSMUSG00000023456(gene)|ensembl:ENSMUST00000172132(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P17751|reactome:R-MMU-70171|reactome:R-MMU-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:1+uasFpsjnuX50Ti23iaIawdp7k10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9QY53 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9QYJ0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772431|ensembl:ENSMUSP00000034138 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dnja2_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short)|uniprotkb:mDj3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062768.1|ensembl:ENSMUSG00000031701(gene)|ensembl:ENSMUST00000034138(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q9QYJ0|reactome:R-MMU-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ZYn3t1WpFrPa82gsMHxjaQRPr3k10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P16045 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1634185|uniprotkb:P05163|uniprotkb:P11946|uniprotkb:P17601|uniprotkb:Q4FZH4|uniprotkb:Q99M27|uniprotkb:Q9D0X0|ensembl:ENSMUSP00000086795 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:leg1_mouse(display_long)|uniprotkb:Lgals1(gene name)|psi-mi:Lgals1(display_short)|uniprotkb:Gbp(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:Lactose-binding lectin 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032521.1|ensembl:ENSMUSG00000068220(gene)|ensembl:ENSMUST00000089377(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005534"(galactose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P16045|rcsb pdb:4LBQ|reactome:R-MMU-381426|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:VMxhs6wVhql3NEex38RQeIwirZs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R060 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286359|uniprotkb:Q9D2E4|uniprotkb:Q9D761 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:zwilc_mouse(display_long)|uniprotkb:Zwilch(gene name)|psi-mi:Zwilch(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080783.3|interpro:IPR018630|go:"GO:0000776"(kinetochore)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:1990423"(RZZ complex)|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:3UABPfI10kxnPFqWKj3qM/FybUM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P80318 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772361|ensembl:ENSMUSP00000001452 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9WTQ5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-643771|uniprotkb:Q80SS4|uniprotkb:Q8BPK4|uniprotkb:Q99MP1|uniprotkb:Q810D4|ensembl:ENSMUSP00000035829 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:aka12_mouse(display_long)|uniprotkb:Ssecks(gene name synonym)|uniprotkb:Src-suppressed C kinase substrate(gene name synonym)|uniprotkb:Germ cell lineage protein gercelin(gene name synonym)|uniprotkb:Akap12(gene name)|psi-mi:Akap12(display_short)|uniprotkb:Gag12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_112462.1|ensembl:ENSMUSG00000038587(gene)|ensembl:ENSMUST00000045730(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061870"(positive regulation of hepatic stellate cell migration)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090036"(regulation of protein kinase C signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1900143"(positive regulation of oligodendrocyte apoptotic process)|interpro:IPR001573(Protein kinase A anchoring region)|interpro:IPR018459|interpro:IPR028540|mint:Q9WTQ5|reactome:R-MMU-9013405|reactome:R-MMU-9035034 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:RXRSkp9BL27+a/XTM8s7aTaXrMc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9ET47 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285094|uniprotkb:A2AK06|uniprotkb:A2AK09|uniprotkb:A2AK13|uniprotkb:B1AWP3|uniprotkb:B1AWP6|uniprotkb:B1AWQ2|uniprotkb:Q6GYS0|uniprotkb:Q6GYS1|uniprotkb:Q80ZC0|uniprotkb:Q80ZC1|uniprotkb:Q80ZC2|uniprotkb:Q80ZC3|uniprotkb:Q9QY27|ensembl:ENSMUSP00000030785 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:espn_mouse(display_long)|uniprotkb:Espn(gene name)|psi-mi:Espn(display_short)|uniprotkb:Ectoplasmic specialization protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_997570.1|refseq:NP_997571.1|refseq:NP_997572.1|refseq:NP_997573.1|refseq:NP_997574.2|ensembl:ENSMUSG00000028943|ensembl:ENSMUSG00000028943|ensembl:ENSMUSG00000028943(gene)|ensembl:ENSMUST00000030785(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030034"(microvillar actin bundle assembly)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0031941"(filamentous actin)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0043197"(dendritic spine)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051494"(negative regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|interpro:IPR002110(Ankyrin)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR020683|interpro:IPR030233|interpro:IPR036770|rcsb pdb:5ET0|rcsb pdb:5ET1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:C6RT3BxZetlVUshumrYseWHabqk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P59913 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4282915|ensembl:ENSMUSP00000059261 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pcmd1_mouse(display_long)|uniprotkb:Pcmtd1(gene name)|psi-mi:Pcmtd1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_898849.1|ensembl:ENSMUSG00000051285(gene)|ensembl:ENSMUST00000061280(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HCK1zY5gjRef1W5wg+vWdKvmt9g10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8C0C7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286479|uniprotkb:Q3U3Q9|uniprotkb:Q91WR4|uniprotkb:Q922S1|ensembl:ENSMUSP00000003906 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:syfa_mouse(display_long)|uniprotkb:Farsa(gene name)|psi-mi:Farsa(display_short)|uniprotkb:Farsla(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_079924.2|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|ensembl:ENSMUSG00000003808(gene)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|ensembl:ENSMUST00000003906(transcript)|go:"GO:0000049"(tRNA binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q8C0C7 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:BSyxrw9ab0HyAuktFxcgvTKUOKE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P63330 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-397144|uniprotkb:O88591|uniprotkb:P13353|uniprotkb:Q5SNY5|ensembl:ENSMUSP00000020608 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pp2aa_mouse(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062284.1|ensembl:ENSMUSG00000020349(gene)|ensembl:ENSMUST00000020608(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P63330|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2995383|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-9648025|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:gpR5Fal3vi6O6cteeGwW72EuctY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14131 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286141|uniprotkb:Q3THM9|ensembl:ENSMUSP00000103940 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs16_mouse(display_long)|uniprotkb:Rps16(gene name)|psi-mi:Rps16(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_038675.2|ensembl:ENSMUSG00000037563(gene)|ensembl:ENSMUST00000082134(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P14131|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-72649 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:OrKriR6HsATLaO+drdUa2w3Gpd010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9DBJ1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1634789|uniprotkb:Q9D6W0|uniprotkb:Q9ERT3|ensembl:ENSMUSP00000011896 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pgam1_mouse(display_long)|uniprotkb:Pgam1(gene name)|psi-mi:Pgam1(display_short)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_075907.2|ensembl:ENSMUSG00000011752(gene)|ensembl:ENSMUST00000011896(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q9DBJ1|reactome:R-MMU-6798695|reactome:R-MMU-70171|reactome:R-MMU-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:yXIwDvILEZUyPCtOTpZy0JxclWg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BHD8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284107|intact:EBI-4286238|uniprotkb:Q3UKB7|uniprotkb:Q8BJT6|uniprotkb:Q8BK38|uniprotkb:Q8C0H6|uniprotkb:Q8R1D5|ensembl:ENSMUSP00000029116 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pcmd2_mouse(display_long)|uniprotkb:Pcmtd2(gene name)|psi-mi:Pcmtd2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_705822.1|uniprotkb:B0R0C8(uniprot-removed-ac)|refseq:NP_001278140.1|ensembl:ENSMUST00000029116(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|ensembl:ENSMUSG00000027589(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:cxvzknx+QmPo2pIM/ZPuYK+uOaE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O35551 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286397|uniprotkb:A1L322|uniprotkb:Q99L08|uniprotkb:Q9CRP3|uniprotkb:Q9EQF9|uniprotkb:Q9JI94|uniprotkb:Q5QNU3|ensembl:ENSMUSP00000075619 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rabe1_mouse(display_long)|uniprotkb:Rabep1(gene name)|psi-mi:Rabep1(display_short)|uniprotkb:Rab5ep(gene name synonym)|uniprotkb:Rabpt5(gene name synonym)|uniprotkb:Rabpt5a(gene name synonym)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062273.2|refseq:NP_001278070.1|refseq:NP_001278071.1|refseq:NP_001278072.1|ensembl:ENSMUSG00000020817(gene)|ensembl:ENSMUST00000076270(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|interpro:IPR029880|mint:O35551 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:aheuMgAZ4SH4NEHk3VzjzwX+UG010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62245 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285534|uniprotkb:P39027|uniprotkb:P39031|uniprotkb:Q8C023|uniprotkb:Q9BV24|ensembl:ENSMUSP00000102198|ensembl:ENSMUSP00000119975|ensembl:ENSMUSP00000127791 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs15a_mouse(display_long)|uniprotkb:Rps15a(gene name)|psi-mi:Rps15a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_733769.1|ensembl:ENSMUSG00000008683(gene)|ensembl:ENSMUST00000106588(transcript)|ensembl:ENSMUST00000131374(transcript)|ensembl:ENSMUST00000172457(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR000630(Ribosomal protein S8)|interpro:IPR035987|mint:P62245|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Qdnhk7yvoFFYcRq5kEi7GQILaxs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q5SWU9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773043|uniprotkb:A2A6H4|uniprotkb:Q5SWU6|uniprotkb:Q5SWU7|uniprotkb:Q5SWU8|uniprotkb:Q6JIZ1|uniprotkb:Q6PHL9|uniprotkb:Q705X8|uniprotkb:Q705X9|uniprotkb:Q91VC8|uniprotkb:Q925C4|uniprotkb:Q925C5|ensembl:ENSMUSP00000020843|ensembl:ENSMUSP00000099490 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:acaca_mouse(display_long)|uniprotkb:ACC-alpha(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase 265(gene name synonym)|uniprotkb:Acaca(gene name)|psi-mi:Acaca(display_short)|uniprotkb:Acac(gene name synonym)|uniprotkb:Gm738(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:XP_011246969.1|refseq:NP_579938.2|refseq:XP_006532016.1|refseq:XP_006532017.1|refseq:XP_006532018.1|refseq:XP_006532019.1|refseq:XP_006532020.1|dip:DIP-32276N|ensembl:ENSMUSG00000020532(gene)|ensembl:ENSMUST00000020843(transcript)|ensembl:ENSMUST00000103201(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009374"(biotin binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q5SWU9|reactome:R-MMU-163765|reactome:R-MMU-196780|reactome:R-MMU-200425|reactome:R-MMU-75105 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:VfXewZAby/B32mkiYMpokapdv1k10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O35887 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-688160|ensembl:ENSMUSP00000031779 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:calu_mouse(display_long)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031620.1|ensembl:ENSMUSG00000029767(gene)|ensembl:ENSMUST00000031779(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019899"(enzyme binding)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O35887|reactome:R-MMU-381426|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:JSG2x2O/Lpg1JYjpePi+aqwSx+g10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R2N2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286120|uniprotkb:Q62306|uniprotkb:Q62307|uniprotkb:Q69Z48|uniprotkb:Q6NVG9|uniprotkb:Q8VEL5|ensembl:ENSMUSP00000048377 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:utp4_mouse(display_long)|uniprotkb:Utp4(gene name)|psi-mi:Utp4(display_short)|uniprotkb:Cirh1a(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:Kiaa1988(gene name synonym)|uniprotkb:Testis-expressed gene 292 protein(gene name synonym)|uniprotkb:Tex292(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035704.2|refseq:XP_006530905.1|ensembl:ENSMUSG00000041438(gene)|ensembl:ENSMUST00000047629(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-MMU-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:fsZvWGOthv3m0TvpBdaXrb3ezRw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14869 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-529949|uniprotkb:Q99L54|ensembl:ENSMUSP00000083705 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rla0_mouse(display_long)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Rplp0(gene name)|psi-mi:Rplp0(display_short)|uniprotkb:Arbp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031501.1|ensembl:ENSMUSG00000067274(gene)|ensembl:ENSMUST00000086519(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042277"(peptide binding)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P14869|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:WHl41TZwjtqRSeIExT3vyjrZsJs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CZX8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-522873|uniprotkb:Q5M9J4|ensembl:ENSMUSP00000104067|ensembl:ENSMUSP00000104068 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs19_mouse(display_long)|uniprotkb:Rps19(gene name)|psi-mi:Rps19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_075622.1|ensembl:ENSMUSG00000040952(gene)|ensembl:ENSMUST00000108429(transcript)|ensembl:ENSMUST00000108430(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:Q9CZX8|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:XP_006539743.1|refseq:XP_006539744.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:D3A6ULv7RIjBdw3qPwrdoWZ+F4U10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62259 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q148V8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4282953|uniprotkb:Q8BZF6|uniprotkb:Q8CI79|uniprotkb:Q8R5C2|uniprotkb:Q8R5D0|ensembl:ENSMUSP00000059839|ensembl:ENSMUSP00000126453 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:fa83h_mouse(display_long)|uniprotkb:Fam83h(gene name)|psi-mi:Fam83h(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001161725.1|refseq:NP_598848.2|refseq:XP_006520300.1|ensembl:ENSMUSG00000046761(gene)|ensembl:ENSMUST00000060807(transcript)|ensembl:ENSMUST00000170153(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:1990254"(keratin filament binding)|interpro:IPR012461(Protein of unknown function DUF1669)|interpro:IPR041996|mint:Q148V8|refseq:XP_006520299.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:3NLWjiNTj+wG44iNYtr/1ghJDu410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14685 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-992014|uniprotkb:Q3TP95|uniprotkb:Q99LL7|ensembl:ENSMUSP00000017365 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:psmd3_mouse(display_long)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:Transplantation antigen P91A(gene name synonym)|uniprotkb:Tum-P91A antigen(gene name synonym)|uniprotkb:Tstap91a(gene name synonym)|uniprotkb:Psmd3(gene name)|psi-mi:Psmd3(display_short)|uniprotkb:P91a(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033465.1|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-MMU-5610785|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|reactome:R-MMU-1169091|reactome:R-MMU-5632684|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-5658442|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-5668541|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-5676590|reactome:R-MMU-2467813|reactome:R-MMU-5687128|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-6798695|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-68827|ensembl:ENSMUSG00000017221(gene)|ensembl:ENSMUST00000017365(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:WUwE+HYUn3TfD5w+LPjn5ouQSCQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O08788 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-776180|uniprotkb:E9QLJ1|uniprotkb:Q3TZG7|ensembl:ENSMUSP00000109552 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dctn1_mouse(display_long)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:Dctn1(gene name)|psi-mi:Dctn1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031861.2|dip:DIP-32057N|ensembl:ENSMUSG00000031865(gene)|ensembl:ENSMUST00000113919(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032402"(melanosome transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:O08788|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:pqj7TtNDgexEbxqLwksW3eW41bo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8VHX6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3UEI1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285611|uniprotkb:Q8K0P4|ensembl:ENSMUSP00000105722 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pde4c_mouse(display_long)|uniprotkb:Pde4c(gene name)|psi-mi:Pde4c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001297394.1|refseq:NP_963901.1|ensembl:ENSMUSG00000031842(gene)|ensembl:ENSMUST00000110095(transcript)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006198"(cAMP catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|reactome:R-MMU-180024|reactome:R-MMU-418555|interpro:IPR040844 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:9i19a6gJizyA/D6kOniVeAsLtic10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91VR2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-444750|ensembl:ENSMUSP00000110547 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:atpg_mouse(display_long)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:Atp5c1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_065640.2|ensembl:ENSMUSG00000025781(gene)|ensembl:ENSMUST00000114897(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|reactome:R-MMU-163210|reactome:R-MMU-8949613 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HXjj4Rj2J2QsW3UFM47mHOYS2VI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q78ZA7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-645017|uniprotkb:O88701|ensembl:ENSMUSP00000072510 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:np1l4_mouse(display_long)|uniprotkb:Nap1l4(gene name)|psi-mi:Nap1l4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001272418.1|refseq:NP_001272419.1|refseq:NP_032698.1|ensembl:ENSMUSG00000059119(gene)|ensembl:ENSMUST00000072727(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0030425"(dendrite)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q78ZA7 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:wEHrLDNg3hwUMaUS8fNw0+AjBz410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6P8K5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284787 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q6p8k5_mouse(display_long)|uniprotkb:Zfp266(gene name)|psi-mi:Zfp266(display_short)|uniprotkb:5730601F06Rik(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:nUcpBNXjbjunGmWL5CynAmzKcrI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q61495 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-397946|uniprotkb:Q8CE03|ensembl:ENSMUSP00000076393|uniprotkb:A8WFQ4 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dsg1a_mouse(display_long)|uniprotkb:Desmosomal glycoprotein I(gene name synonym)|uniprotkb:DG1(gene name synonym)|uniprotkb:DGI(gene name synonym)|uniprotkb:Dsg1a(gene name)|psi-mi:Dsg1a(display_short)|uniprotkb:Dsg1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034209.2|ensembl:ENSMUSG00000069441(gene)|ensembl:ENSMUST00000077146(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696270 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qT1MQ4BvfgVXy4wU4AwVIz3SueY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P17879 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-397360|uniprotkb:Q61689|uniprotkb:Q925V6|ensembl:ENSMUSP00000133815 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hs71b_mouse(display_long)|uniprotkb:Hspa1b(gene name)|psi-mi:Hspa1b(display_short)|uniprotkb:Hcp70.1(gene name synonym)|uniprotkb:Hsp70-1(gene name synonym)|uniprotkb:Hsp70a1(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:Hspa1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034608.2|dip:DIP-31549N|ensembl:ENSMUSG00000090877(gene)|ensembl:ENSMUST00000172753(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|mint:P17879|reactome:R-MMU-3371453|go:"GO:0005739"(mitochondrion)|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-450408|reactome:R-MMU-6798695|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:IjedYF1eneAZUEXux0xxZLvp6oI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8CI43 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286253|ensembl:ENSMUSP00000026428 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:myl6b_mouse(display_long)|uniprotkb:Myl6b(gene name)|psi-mi:Myl6b(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_758463.1|ensembl:ENSMUSG00000039824(gene)|ensembl:ENSMUST00000026428(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|reactome:R-MMU-445355|refseq:XP_017169402.1|refseq:XP_017169403.1|refseq:XP_017169404.1|refseq:XP_017169405.1|refseq:XP_017169406.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:SqvRDqPjO60DFT+dkkbnosxuBnk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BIY3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285697|uniprotkb:A4FU74 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:zc12d_mouse(display_long)|uniprotkb:Zc3h12d(gene name)|psi-mi:Zc3h12d(display_short)|uniprotkb:Mcpip4(gene name synonym)|uniprotkb:Tfl(gene name synonym)|uniprotkb:MCP-induced protein 4(gene name synonym)|uniprotkb:Transformed follicular lymphoma homolog(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR040546|refseq:NP_766373.2|interpro:IPR021869|interpro:IPR000571(Zinc finger, CCCH-type)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:8+h1hWHxFVckr29F0BqNhLpd57410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9DBC7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-645677|uniprotkb:Q3UKU7|uniprotkb:Q9JHR5|uniprotkb:Q9JHR6|ensembl:ENSMUSP00000056500|ensembl:ENSMUSP00000102288 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:kap0_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001300902.1|refseq:NP_001300903.1|refseq:NP_001300904.1|refseq:NP_001300905.1|refseq:NP_068680.1|refseq:XP_017169829.1|dip:DIP-32450N|ensembl:ENSMUSG00000020612(gene)|ensembl:ENSMUST00000049527(transcript)|ensembl:ENSMUST00000106677(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007507"(heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|reactome:R-MMU-983231|reactome:R-MMU-5610787|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q9DBC7|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-432040|go:"GO:0043949"(regulation of cAMP-mediated signaling)|reactome:R-MMU-442720 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:0KqlQxZjK8QfS6VPEiTDtvHNTj410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BG32 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-992214|ensembl:ENSMUSP00000017572|ensembl:ENSMUSP00000133571 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:psd11_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:Psmd11(gene name)|psi-mi:Psmd11(display_short)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_848731.2|ensembl:ENSMUSG00000017428(gene)|ensembl:ENSMUST00000017572(transcript)|ensembl:ENSMUST00000173938(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR040773|go:"GO:0048863"(stem cell differentiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040780|mint:Q8BG32|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-75815 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:J0WRN/hjSLPvj9mR+VMFZrkHSk410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q80X90 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-688023|intact:EBI-777273|uniprotkb:E9QNV9|uniprotkb:Q8VHX4|uniprotkb:Q8VHX7|uniprotkb:Q99KY3|ensembl:ENSMUSP00000052020 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:flnb_mouse(display_long)|uniprotkb:Flnb(gene name)|psi-mi:Flnb(display_short)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001074896.1|ensembl:ENSMUSG00000025278(gene)|ensembl:ENSMUST00000052678(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:Q80X90|reactome:R-MMU-1169408|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:A5bnyO/GwzIgn56NbxZGMkAWYk410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14206 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R1N4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284981|uniprotkb:Q3TX16|uniprotkb:Q5SVV6|uniprotkb:Q5SVV7|uniprotkb:Q6PFE4|uniprotkb:Q6ZPZ2|uniprotkb:Q8BL70|uniprotkb:Q8BWN3|uniprotkb:Q8BWW5|ensembl:ENSMUSP00000064668 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nudc3_mouse(display_long)|uniprotkb:Nudcd3(gene name)|psi-mi:Nudcd3(display_short)|uniprotkb:Kiaa1068(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_776109.1|refseq:XP_006514666.1|ensembl:ENSMUSG00000053838(gene)|ensembl:ENSMUST00000066496(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1905793"(protein localization to pericentriolar material)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR027761|interpro:IPR037898|interpro:IPR037905 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:k4TCovssxr/bbgPwT8AZfcQU8Yg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P20917 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-774926|uniprotkb:P16880|uniprotkb:A0A087WPR1|ensembl:ENSMUSP00000139881 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:mag_mouse(display_long)|uniprotkb:Siglec-4a(gene name synonym)|uniprotkb:Mag(gene name)|psi-mi:Mag(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001333015.1|refseq:NP_001333016.1|refseq:NP_034888.1|refseq:XP_011248743.1|refseq:NP_001333017.1|refseq:XP_017177497.1|refseq:NP_001333013.1|refseq:NP_001333014.1|refseq:XP_006539653.1|refseq:XP_006539654.1|refseq:XP_011248740.1|refseq:XP_011248741.1|refseq:XP_011248742.1|refseq:XP_017177496.1|ensembl:ENSMUSG00000036634(gene)|ensembl:ENSMUST00000191081(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097453"(mesaxon)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P20917|rcsb pdb:5LF5|rcsb pdb:5LFR|rcsb pdb:5LFU|rcsb pdb:5LFV|rcsb pdb:6GZJ|rcsb pdb:6GZL|reactome:R-MMU-193634|reactome:R-MMU-210991 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:sgxaYqIU4i2tAdeRMT9/UqKO0Qo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q64520 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284800|uniprotkb:Q564F2|uniprotkb:Q564G0 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:kgua_mouse(display_long)|uniprotkb:Guk1(gene name)|psi-mi:Guk1(display_short)|uniprotkb:Gmk(gene name synonym)|uniprotkb:GMP kinase(gene name synonym)|uniprotkb:Guanylate kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR017665(Guanylate kinase, sub-group)|mint:Q64520|refseq:XP_006532308.1|refseq:XP_006532309.1|interpro:IPR027417|go:"GO:0046054"(dGMP metabolic process)|go:"GO:0046060"(dATP metabolic process)|go:"GO:0046711"(GDP biosynthetic process)|go:"GO:0046939"(nucleotide phosphorylation)|rcsb pdb:1LVG|reactome:R-MMU-499943|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0006185"(dGDP biosynthetic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0034436"(glycoprotein transport)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046037"(GMP metabolic process)|refseq:NP_001152882.1|refseq:NP_032219.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:zwGxgpRae+80ByjXzyOjfzU5EYw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q03265 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9Z1J1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-646762|uniprotkb:O70450|uniprotkb:O70573 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tf7l1_mouse(display_long)|uniprotkb:HMG box transcription factor 3(gene name synonym)|uniprotkb:Tcf7l1(gene name)|psi-mi:Tcf7l1(display_short)|uniprotkb:Tcf3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033358.2|dip:DIP-49605N|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043588"(skin development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|reactome:R-MMU-201722|reactome:R-MMU-3769402|reactome:R-MMU-4641265|reactome:R-MMU-8951430|reactome:R-MMU-4086398|reactome:R-MMU-8853884 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:l/DKng9W5qg5AQVpnfjPVIfaE+w10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62264 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2311514|uniprotkb:P06366|uniprotkb:Q544W4|ensembl:ENSMUSP00000025511|ensembl:ENSMUSP00000113081|ensembl:ENSMUSP00000113504|ensembl:ENSMUSP00000157948|ensembl:ENSMUSP00000158138 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs14_mouse(display_long)|uniprotkb:Rps14(gene name)|psi-mi:Rps14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_065625.2|ensembl:ENSMUSG00000024608(gene)|ensembl:ENSMUST00000025511(transcript)|ensembl:ENSMUST00000118551(transcript)|ensembl:ENSMUST00000122279(transcript)|ensembl:ENSMUST00000235603(transcript)|ensembl:ENSMUST00000235966(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62264|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D824 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284884|uniprotkb:Q8BWX7|uniprotkb:Q99LH0|uniprotkb:Q9DBB2|ensembl:ENSMUSP00000109164 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:fip1_mouse(display_long)|uniprotkb:Fip1l1(gene name)|psi-mi:Fip1l1(display_short)|uniprotkb:FIP1-like 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_077145.2|refseq:NP_001153045.1|refseq:NP_001153046.1|ensembl:ENSMUSG00000029227(gene)|ensembl:ENSMUST00000113536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q9D824|reactome:R-MMU-159231|reactome:R-MMU-72163|reactome:R-MMU-73856|reactome:R-MMU-72187|reactome:R-MMU-77595 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HUvxO7hcgX/waTp9pYqFuxXH9Ko10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BTM8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-641991|uniprotkb:B7FAV0|uniprotkb:O54934|uniprotkb:Q7TQI1|uniprotkb:Q8BLK1|uniprotkb:Q8BTN7|uniprotkb:Q8VHX5|uniprotkb:Q8VHX8|uniprotkb:Q99KQ2|ensembl:ENSMUSP00000033699 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:flna_mouse(display_long)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Fln(gene name synonym)|uniprotkb:Fln1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:XP_006527974.1|ensembl:ENSMUST00000033699(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|ensembl:ENSMUSG00000031328(gene)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q8BTM8|reactome:R-MMU-114608|reactome:R-MMU-430116|reactome:R-MMU-446353|reactome:R-MMU-5627123 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:hp3whHs7nFMTtChpQ/KywkPalq810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O08614 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285301 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:o08614_mouse(display_long)|uniprotkb:Utrn(gene name)|psi-mi:Utrn(display_short)|uniprotkb:utrophin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR000433(Zinc finger, ZZ-type)|mint:O08614|interpro:IPR036020|interpro:IPR036872|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008270"(zinc ion binding)|interpro:IPR035436|interpro:IPR043145 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:nzdkC5iTKAQUH8tJQjqpr3Tdm9o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62082 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-354350|uniprotkb:P24818|uniprotkb:P23821|ensembl:ENSMUSP00000073880|ensembl:ENSMUSP00000152456 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs7_mouse(display_long)|uniprotkb:Rps7(gene name)|psi-mi:Rps7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035430.1|ensembl:ENSMUSG00000061477(gene)|ensembl:ENSMUST00000074267(transcript)|ensembl:ENSMUST00000221871(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62082|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0032040"(small-subunit processome) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P28658 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9R0L6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284371|uniprotkb:O70287|uniprotkb:Q3URH6|uniprotkb:Q7TMS7|uniprotkb:Q8C9V2|uniprotkb:Q91Y27|uniprotkb:Q91Y28|uniprotkb:Q91Y51|uniprotkb:Q9CRK8|uniprotkb:Q923L0|uniprotkb:Q9CT57|uniprotkb:E9QLK2|ensembl:ENSMUSP00000039709 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pcm1_mouse(display_long)|uniprotkb:Pcm1(gene name)|psi-mi:Pcm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_076151.2|refseq:XP_006509361.1|ensembl:ENSMUSG00000031592(gene)|ensembl:ENSMUST00000045218(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q9R0L6|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-5620912|reactome:R-MMU-8854518|reactome:R-MMU-380320 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:OT+ZOQY5pqQojMcLCWMIY+6zdl410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q62465 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-911848|uniprotkb:Q8R3G0|uniprotkb:Q8R3T8|ensembl:ENSMUSP00000048350 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:vat1_mouse(display_long)|uniprotkb:Vat1(gene name)|psi-mi:Vat1(display_short)|uniprotkb:Vat-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000034993(gene)|ensembl:ENSMUST00000040430(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q62465|reactome:R-MMU-6798695|refseq:NP_036167.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:z+QTKmncP2v/Qu1qdcPUTPMozVQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:B2RQC6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-3043834|ensembl:ENSMUSP00000013773|uniprotkb:B7ZN27 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pyr1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000013629(gene)|ensembl:ENSMUST00000013773(transcript)|go:"GO:0002134"(UTP binding)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0001889"(liver development)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|go:"GO:0019899"(enzyme binding)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:B2RQC6|reactome:R-MMU-500753|refseq:NP_076014.1|refseq:NP_001276451.1|dip:DIP-61412N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:t+qQw7me78vEm/Y4VBBhS8fmCsY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q5SWD9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286444|uniprotkb:Q3TMW6|uniprotkb:Q3TRK6|uniprotkb:Q3U4T2|uniprotkb:Q3UYU4|uniprotkb:Q3V3X8|uniprotkb:Q6ZPR9|uniprotkb:Q8K2F5|ensembl:ENSMUSP00000039027 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tsr1_mouse(display_long)|uniprotkb:Tsr1(gene name)|psi-mi:Tsr1(display_short)|uniprotkb:Kiaa1401(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_796299.2|ensembl:ENSMUSG00000038335(gene)|ensembl:ENSMUST00000045807(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR030387|interpro:IPR039761|reactome:R-MMU-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:QFezbfcysf3XPyH65BIGtX9AVG010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3ULW5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285755 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3ulw5_mouse(display_long)|uniprotkb:Ftl1(gene name)|psi-mi:Ftl1(display_short)|uniprotkb:Ftl2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR009040(Ferritin-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR014034(Ferritin, conserved site)|interpro:IPR008331(Ferritin and Dps)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008199"(ferric iron binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:k8IkX0enSMmNB7tS39xHqk3PBaA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BWT1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:15aWO97WJBNGYD449bAgjVjkgTY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q61177 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1216438 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q61177_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:WjL03qwk8iDJOV9w6r6n4vazPis10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P97351 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773982|ensembl:ENSMUSP00000029722 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs3a_mouse(display_long)|uniprotkb:Rps3a(gene name)|psi-mi:Rps3a(display_short)|uniprotkb:Protein TU-11(gene name synonym)|uniprotkb:Rps3a1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_058655.3|ensembl:ENSMUSG00000028081(gene)|ensembl:ENSMUST00000029722(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:pi623FvaPjjNAiN44zPHjtep4gs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9R0P9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1635245|uniprotkb:Q9R122|ensembl:ENSMUSP00000031131 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:uchl1_mouse(display_long)|uniprotkb:Uchl1(gene name)|psi-mi:Uchl1(display_short)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035800.2|ensembl:ENSMUSG00000029223(gene)|ensembl:ENSMUST00000031131(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007409"(axonogenesis)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:0055001"(muscle cell development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:Q9R0P9|reactome:R-MMU-5689603|go:"GO:0019233"(sensory perception of pain) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:OwNZHaBcqFPb5UKgm9WtL6AXn/o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9JI10 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285880|uniprotkb:Q60877|uniprotkb:Q80UG4|uniprotkb:Q8CI58|ensembl:ENSMUSP00000018476 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:stk3_mouse(display_long)|uniprotkb:Mst2(gene name synonym)|uniprotkb:Stk3(gene name)|psi-mi:Stk3(display_short)|uniprotkb:Mess1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:STE20-like kinase MST2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062609.2|ensembl:ENSMUSG00000022329(gene)|ensembl:ENSMUST00000018476(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q9JI10|reactome:R-MMU-2028269|dip:DIP-61760N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:F1GEMB9TES32FDkAIPtuXIxbEoI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BP92 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-642694|uniprotkb:O70341|uniprotkb:A2RT07|ensembl:ENSMUSP00000109915 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rcn2_mouse(display_long)|uniprotkb:Taipoxin-associated calcium-binding protein 49(gene name synonym)|uniprotkb:Rcn2(gene name)|psi-mi:Rcn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_036122.2|ensembl:ENSMUSG00000032320(gene)|ensembl:ENSMUST00000114276(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8BP92|dip:DIP-46963N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:vsMMmWAPrlDNQDUxzH4wrp1Jub410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P61982 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62702 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-354261|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q9CXN0|uniprotkb:P55831|uniprotkb:Q14727|ensembl:ENSMUSP00000033683 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs4x_mouse(display_long)|uniprotkb:Rps4(gene name synonym)|uniprotkb:Rps4x(gene name)|psi-mi:Rps4x(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033120.1|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000031320(gene)|ensembl:ENSMUST00000033683(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62702|reactome:R-MMU-156827|go:"GO:0003723"(RNA binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8CE72 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285912|ensembl:ENSMUSP00000106247|uniprotkb:E9QL36|uniprotkb:Q3UXY6|uniprotkb:Q6PEE0 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cpln1_mouse(display_long)|uniprotkb:Cplane1(gene name)|psi-mi:Cplane1(display_short)|uniprotkb:Jbts17(gene name synonym)|uniprotkb:Protein C5orf42 homolog(gene name synonym)|uniprotkb:Protein JBTS17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001156378.1|ensembl:ENSMUSG00000039801(gene)|ensembl:ENSMUST00000110617(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0007507"(heart development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR028236 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:uDH3PIGBEfdbp9naNmK8t4/771o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3UYW8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286192 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3uyw8_mouse(display_long)|uniprotkb:Ahnak(gene name)|psi-mi:Ahnak(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:fICu34mdvfxdt022GSFTqaMMVEA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q64337 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-645025|uniprotkb:Q99JM8|ensembl:ENSMUSP00000099835 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:sqstm_mouse(display_long)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:STONE14(gene name synonym)|uniprotkb:Sqstm1(gene name)|psi-mi:Sqstm1(display_short)|uniprotkb:A170(gene name synonym)|uniprotkb:STAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001277698.1|refseq:NP_035148.1|ensembl:ENSMUSG00000015837(gene)|ensembl:ENSMUST00000102774(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR033741|interpro:IPR034866|interpro:IPR043145|mint:Q64337|rcsb pdb:2RRU|rcsb pdb:2ZJD|rcsb pdb:3ADE|rcsb pdb:3B0F|rcsb pdb:3WDZ|reactome:R-MMU-205043|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-5205685|reactome:R-MMU-9020702|reactome:R-MMU-9664873|dip:DIP-38490N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:/BktZPkmiLsU1fKVqPSQ8ae2+SY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R323 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-529792|ensembl:ENSMUSP00000039621 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rfc3_mouse(display_long)|uniprotkb:Activator 1 subunit 3(gene name synonym)|uniprotkb:Replication factor C 38 kDa subunit(gene name synonym)|uniprotkb:Activator 1 38 kDa subunit(gene name synonym)|uniprotkb:Rfc3(gene name)|psi-mi:Rfc3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_081285.1|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473|ensembl:ENSMUSG00000033970(gene)|ensembl:ENSMUST00000038131(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:A8JvnEC8Eg1fhQp8+Zs1OFqYQK010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P68254 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-400675|uniprotkb:P35216|uniprotkb:Q3TW69|uniprotkb:Q3UJN5|uniprotkb:Q5SP76|uniprotkb:Q5U423|uniprotkb:Q66JR6|ensembl:ENSMUSP00000100067|ensembl:ENSMUSP00000123605 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:1433t_mouse(display_long)|uniprotkb:Ywhaq(gene name)|psi-mi:Ywhaq(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035869.1|ensembl:ENSMUSG00000076432(gene)|ensembl:ENSMUST00000103002(transcript)|ensembl:ENSMUST00000135088(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P68254|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9614399 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:l8bki6QJJEH5S5NIwQdm/MAYcc010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P46471 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-991874|uniprotkb:O08531|uniprotkb:Q3TGX5|uniprotkb:Q9DBA1|ensembl:ENSMUSP00000030769 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:prs7_mouse(display_long)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:Psmc2(gene name)|psi-mi:Psmc2(display_short)|uniprotkb:Mss1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000028932(gene)|ensembl:ENSMUST00000030769(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P46471|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|refseq:NP_035318.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:vmk/q/Ii3bbspEB4N9hS9HEjVGk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62858 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286041|uniprotkb:P25112|uniprotkb:Q5BKQ7|ensembl:ENSMUSP00000110013|ensembl:ENSMUSP00000133357|ensembl:ENSMUSP00000133642|ensembl:ENSMUSP00000134615 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs28_mouse(display_long)|uniprotkb:Rps28(gene name)|psi-mi:Rps28(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_058540.1|ensembl:ENSMUSG00000067288(gene)|ensembl:ENSMUST00000087342(transcript)|ensembl:ENSMUST00000166693(transcript)|ensembl:ENSMUST00000173019(transcript)|ensembl:ENSMUST00000173844(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|mint:P62858|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:XP_006524687.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:G4t8mOlzIiHEOXu+uS+AfySWAnM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P63101 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62823 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286215|uniprotkb:Q62858|uniprotkb:Q62974|uniprotkb:Q63482|uniprotkb:Q9CXQ1|ensembl:ENSMUSP00000132945 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rab3c_mouse(display_long)|uniprotkb:Rab3c(gene name)|psi-mi:Rab3c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_076341.1|ensembl:ENSMUSG00000021700(gene)|ensembl:ENSMUST00000167824(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|reactome:R-MMU-8873719 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:F0BXS2E7Unlk+uNhGFX8SXRN9hA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8C0L3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285741 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q8c0l3_mouse(display_long)|uniprotkb:Zfp869(gene name)|psi-mi:Zfp869(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR036051|interpro:IPR036236|refseq:NP_001035056.1|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070895"(negative regulation of transposon integration) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:auPxTbOUCo6YCrz9+aY8raFcJ3I10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62196 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-357713|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:Q3UL51|uniprotkb:P52915|uniprotkb:P52916|uniprotkb:Q9CWN5|ensembl:ENSMUSP00000021049 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:prs8_mouse(display_long)|uniprotkb:Psmc5(gene name)|psi-mi:Psmc5(display_short)|uniprotkb:Sug1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032976.1|ensembl:ENSMUSG00000020708(gene)|ensembl:ENSMUST00000021049(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62196|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|dip:DIP-35174N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62908 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299793|ensembl:ENSMUSP00000032998|uniprotkb:P17073|uniprotkb:P47933 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs3_mouse(display_long)|uniprotkb:Rps3(gene name)|psi-mi:Rps3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000030744(gene)|ensembl:ENSMUST00000032998(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR018280|interpro:IPR036419|mint:P62908|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_036182.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:f4Vh6HESE+lKZinjkJ883IG3wiY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CQS5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284935|uniprotkb:Q91XF3|ensembl:ENSMUSP00000024620 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:riok2_mouse(display_long)|uniprotkb:Riok2(gene name)|psi-mi:Riok2(display_short)|uniprotkb:RIO kinase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080210.1|ensembl:ENSMUST00000024620(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000208"(positive regulation of ribosomal small subunit export from nucleus)|ensembl:ENSMUSG00000116564(gene)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015285(RIO2 kinase, winged helix, N-terminal)|interpro:IPR018935|interpro:IPR030484|interpro:IPR036388|interpro:IPR036390|reactome:R-MMU-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:bDp93jQ73Qy3/ZrL3sdSJgmkIik10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62821 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1634955|uniprotkb:P11476|uniprotkb:Q3TX44|uniprotkb:Q811M4|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|ensembl:ENSMUSP00000127330 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rab1a_mouse(display_long)|uniprotkb:Rab1A(gene name)|psi-mi:Rab1A(display_short)|uniprotkb:Rab1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033022.1|ensembl:ENSMUSG00000020149(gene)|ensembl:ENSMUST00000163483(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0032402"(melanosome transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0098793"(presynapse)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62821|reactome:R-MMU-162658|reactome:R-MMU-204005|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-8873719|reactome:R-MMU-8876198 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3V2E0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4281451 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3v2e0_mouse(display_long)|uniprotkb:Try5(gene name)|psi-mi:Try5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR033116|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR043504 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:2D7DR7UChhapYkFYQMLQzHaxl2E10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8K0L9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285176|uniprotkb:A6X916|uniprotkb:Q9DBD4|uniprotkb:Q9QZ87|ensembl:ENSMUSP00000078410|ensembl:ENSMUSP00000110342|ensembl:ENSMUSP00000110343 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:zbt20_mouse(display_long)|uniprotkb:Zbtb20(gene name)|psi-mi:Zbtb20(display_short)|uniprotkb:Zfp288(gene name synonym)|uniprotkb:BTB/POZ domain zinc finger factor HOF(gene name synonym)|uniprotkb:Zinc finger protein 288(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062752.2|refseq:NP_851401.1|refseq:NP_001272734.1|refseq:XP_011244291.1|refseq:XP_011244292.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSMUSG00000022708(gene)|ensembl:ENSMUST00000079441(transcript)|ensembl:ENSMUST00000114694(transcript)|ensembl:ENSMUST00000114695(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006522475.1|refseq:XP_006522476.1|refseq:XP_006522477.1|refseq:XP_006522478.1|refseq:XP_006522479.1|refseq:XP_006522481.1|refseq:XP_006522485.1|refseq:XP_006522487.1|refseq:XP_017172580.1|refseq:XP_017172581.1|refseq:XP_017172582.1|refseq:XP_017172583.1|refseq:XP_017172584.1|refseq:XP_017172585.1|refseq:XP_017172586.1|refseq:XP_017172587.1|refseq:XP_017172588.1|refseq:XP_017172589.1|refseq:XP_017172590.1|refseq:XP_017172591.1|refseq:XP_017172592.1|refseq:XP_017172593.1|refseq:XP_017172594.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:kYpz/BsoVFBnowBv9k9YkjZrUF010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q62158 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-642025|uniprotkb:Q62157|uniprotkb:Q8C2Q5|uniprotkb:Q99LK1|ensembl:ENSMUSP00000021761|ensembl:ENSMUSP00000152730 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tri27_mouse(display_long)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:Trim27(gene name)|psi-mi:Trim27(display_short)|uniprotkb:Rfp(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033080.2|refseq:XP_006516669.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0016605"(PML body)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:Q62158|reactome:R-MMU-3232142|reactome:R-MMU-8948751|ensembl:ENSMUSG00000021326(gene)|ensembl:ENSMUST00000021761(transcript)|ensembl:ENSMUST00000222544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ay3vOvfbC0rFrDbLB0NsvrT9eBw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D0K2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-645913|uniprotkb:Q9CV92|uniprotkb:Q3TIW6|ensembl:ENSMUSP00000106318 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:scot1_mouse(display_long)|uniprotkb:"Somatic-type succinyl-CoA:3-oxoacid CoA-transferase"(gene name synonym)|uniprotkb:Oxct1(gene name)|psi-mi:Oxct1(display_short)|uniprotkb:Oxct(gene name synonym)|uniprotkb:Scot(gene name synonym)|uniprotkb:3-oxoacid CoA-transferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_077150.1|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|mint:Q9D0K2|reactome:R-MMU-77108|ensembl:ENSMUST00000110690(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042182"(ketone catabolic process)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|ensembl:ENSMUSG00000022186(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:KSJpQdbufFtI07fqqPLQdJrkT2I10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q0P678 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285772|uniprotkb:Q3TKW3|uniprotkb:Q52KI3|uniprotkb:Q6KAL8|uniprotkb:Q9CU64|ensembl:ENSMUSP00000090761 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:zch18_mouse(display_long)|uniprotkb:Zc3h18(gene name)|psi-mi:Zc3h18(display_short)|uniprotkb:Nhn1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUST00000093073(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|refseq:NP_001025164.1|refseq:NP_001025165.1|refseq:NP_001297579.1|ensembl:ENSMUSG00000017478(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:yQXtDYpTOE6hdaKBFQskL/GDgvw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q5SWZ5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284968|ensembl:ENSMUSP00000071081 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q5swz5_mouse(display_long)|uniprotkb:Mprip(gene name)|psi-mi:Mprip(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:XP_006533496.1|ensembl:ENSMUSG00000005417(gene)|ensembl:ENSMUST00000066330(transcript)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:6lU4R/qphHiCXbmN4LWYhuX/0Pg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9Z1R2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-644645|uniprotkb:Q8SNA3|ensembl:ENSMUSP00000025250 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:bag6_mouse(display_long)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Bat3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:Bag6(gene name)|psi-mi:Bag6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_476512.1|ensembl:ENSMUSG00000024392(gene)|ensembl:ENSMUST00000025250(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:Q9Z1R2|dip:DIP-49391N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:psW3TZRi1goIL8R7JOGiBON/bk810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P68372 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3TF41 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284926|ensembl:ENSMUSP00000151507 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3tf41_mouse(display_long)|uniprotkb:Nap1l1(gene name)|psi-mi:Nap1l1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000058799(gene)|ensembl:ENSMUST00000219143(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:mabX18CulEoR4ssSy4yx/z//UDg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9ERG2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-911729|ensembl:ENSMUSP00000013130 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:strn3_mouse(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:Strn3(gene name)|psi-mi:Strn3(display_short)|uniprotkb:Gs2na(gene name synonym)|uniprotkb:Sg2na(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000020954(gene)|ensembl:ENSMUST00000013130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR001680(WD40 repeat)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERG2|refseq:NP_443205.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:TdtwkF77kxNiBo0jtPGVLwUlxoI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91YT7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286305|uniprotkb:Q3TWU3|uniprotkb:Q8BM70|uniprotkb:Q8K325|ensembl:ENSMUSP00000120414 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ythd2_mouse(display_long)|uniprotkb:Ythdf2(gene name)|psi-mi:Ythdf2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_663368.3|ensembl:ENSMUSG00000040025(gene)|ensembl:ENSMUST00000152796(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070925"(organelle assembly)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|go:"GO:0005634"(nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:mMOth3TafazhsFBquXonvgj6Jz010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P80316 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772379|uniprotkb:Q3TIE0|uniprotkb:Q3U530|uniprotkb:Q3UCU4|uniprotkb:Q3UJK9|uniprotkb:Q3UWA9|uniprotkb:Q542K3|uniprotkb:Q6ZQJ1|ensembl:ENSMUSP00000022842 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpe_mouse(display_long)|uniprotkb:CCT-epsilon(gene name synonym)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:Ccte(gene name synonym)|uniprotkb:Kiaa0098(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031663.1|refseq:NP_001334964.1|ensembl:ENSMUSG00000022234(gene)|ensembl:ENSMUST00000022842(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80316|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:UpEEjKLyd92Zl4VnOTTlziuwAGA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q05BF4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285147|ensembl:ENSMUSP00000131469|ensembl:ENSMUSP00000135742 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q05bf4_mouse(display_long)|uniprotkb:Wdr37(gene name)|psi-mi:Wdr37(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001034478.1|ensembl:ENSMUST00000164183(transcript)|ensembl:ENSMUST00000176922(transcript)|ensembl:ENSMUSG00000021147(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:C8ACTxWXtoQcnTGnXQNk7P8N5QI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P70335 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-989293|uniprotkb:Q8C3G4|uniprotkb:Q8C7H0|ensembl:ENSMUSP00000069549 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rock1_mouse(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)|uniprotkb:p160 ROCK-1(gene name synonym)|uniprotkb:Rock1(gene name)|psi-mi:Rock1(display_short)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0007159"(leukocyte cell-cell adhesion)|ensembl:ENSMUSG00000024290(gene)|ensembl:ENSMUST00000067947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003383"(apical constriction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0071559"(response to transforming growth factor beta)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037310|mint:P70335|reactome:R-MMU-111465|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-416572|reactome:R-MMU-4420097|reactome:R-MMU-5627117|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013407|reactome:R-MMU-9013422|reactome:R-MMU-9696264|interpro:IPR011072(HR1 rho-binding repeat)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032059"(bleb)|go:"GO:0032060"(bleb assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051451"(myoblast migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|refseq:NP_033097.1|refseq:XP_006525788.1|dip:DIP-35521N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:BIAb7c+Ar8WI6cES/igerUjk1zc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q60668 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299932|ensembl:ENSMUSP00000132735|uniprotkb:Q91X94|uniprotkb:Q60667|uniprotkb:Q80ZJ0 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hnrpd_mouse(display_long)|uniprotkb:Hnrnpd(gene name)|psi-mi:Hnrnpd(display_short)|uniprotkb:Auf1(gene name synonym)|uniprotkb:Hnrpd(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000000568(gene)|ensembl:ENSMUST00000172361(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q60668|reactome:R-MMU-450408|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0042752"(regulation of circadian rhythm)|refseq:NP_001070733.1|refseq:NP_001070734.1|refseq:NP_001070735.1|refseq:NP_031542.2|refseq:XP_006534798.1|dip:DIP-31411N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:lGvmHnn59pHQTtZq6H6ijlvXvt010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3U3T8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2365469|uniprotkb:Q6PGG0|uniprotkb:Q7TQE9 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:wdr62_mouse(display_long)|uniprotkb:Wdr62(gene name)|psi-mi:Wdr62(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR024977|mint:Q3U3T8|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0097150"(neuronal stem cell population maintenance) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:l1ykYPJWylrUCk6FY/w9DHoAZz810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3UVD5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285460|uniprotkb:Q80UB8|uniprotkb:Q8R301|ensembl:ENSMUSP00000035444|uniprotkb:B2RUL8 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:lgr6_mouse(display_long)|uniprotkb:Lgr6(gene name)|psi-mi:Lgr6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001028581.1|ensembl:ENSMUSG00000042793(gene)|ensembl:ENSMUST00000044828(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016500"(protein-hormone receptor activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042246"(tissue regeneration)|go:"GO:1990523"(bone regeneration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:6AG0n8WN2iUVkjyJXs5O4GkcfM010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3TIQ2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285477 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3tiq2_mouse(display_long)|uniprotkb:Rpl12(gene name)|psi-mi:Rpl12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR036769|interpro:IPR036796|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:3BwXPMWQ/oMplk3l/7Gvwkqxpf410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CWF2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2794256|uniprotkb:Q3TG26|ensembl:ENSMUSP00000075178 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tbb2b_mouse(display_long)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_076205.1|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9CWF2|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|ensembl:ENSMUSG00000045136(gene)|ensembl:ENSMUST00000075774(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:sluQMryNuOvp6xlV558+agiRwvE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q921U8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285038|uniprotkb:Q3TCV2|uniprotkb:Q6NSW1|uniprotkb:Q8CD93|uniprotkb:Q9JHG8|uniprotkb:Q9JLU7|uniprotkb:Q9R0D0|uniprotkb:Q9R253|uniprotkb:Q9Z0Q2|ensembl:ENSMUSP00000074621 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:smtn_mouse(display_long)|uniprotkb:Smtn(gene name)|psi-mi:Smtn(display_short)|uniprotkb:Smsmo(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001152756.1|refseq:NP_038898.2|refseq:NP_001271356.1|refseq:NP_001271357.1|refseq:NP_001271358.1|refseq:XP_017170075.1|ensembl:ENSMUSG00000020439(gene)|ensembl:ENSMUST00000075118(transcript)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:Q921U8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:buMeLGcMCw9xVDdWao7z+fXj9Bc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P80315 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772370|ensembl:ENSMUSP00000133523 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpd_mouse(display_long)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:A45(gene name synonym)|uniprotkb:Cct4(gene name)|psi-mi:Cct4(display_short)|uniprotkb:Cctd(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033967.1|ensembl:ENSMUSG00000007739(gene)|ensembl:ENSMUST00000173867(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80315|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:/40BY5vhE/fuloWu9L2k7ujy9Nc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9Z2X1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8VDB8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285281|uniprotkb:Q9CX04 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:lrrc2_mouse(display_long)|uniprotkb:Lrrc2(gene name)|psi-mi:Lrrc2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_083114.2|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR025875|refseq:XP_006512428.1|interpro:IPR032675|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HNfBgvFRs77lSA6+koR8NI6ehhI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CWK0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286270 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q9cwk0_mouse(display_long)|uniprotkb:Rpl14(gene name)|psi-mi:Rpl14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR002784(Ribosomal protein L14)|interpro:IPR014722(Translation protein SH3-like, subgroup)|mint:Q9CWK0|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR041985 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:7cOC2RFf58l9cMSA2Y4a4UjQ4hg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8C6G8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285076|uniprotkb:Q3TK81|uniprotkb:Q8C4F3|uniprotkb:Q8VDZ6|uniprotkb:E9PX83|ensembl:ENSMUSP00000124592 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:wdr26_mouse(display_long)|uniprotkb:Wdr26(gene name)|psi-mi:Wdr26(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_663489.4|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|ensembl:ENSMUSG00000038733(gene)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|ensembl:ENSMUST00000162819(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:n7KV+Q8UA8RP/yXbL9IdoevU+mE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P99024 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P31230 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285838|uniprotkb:Q60659|ensembl:ENSMUSP00000142513 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:aimp1_mouse(display_long)|uniprotkb:Aimp1(gene name)|psi-mi:Aimp1(display_short)|uniprotkb:Emap2(gene name synonym)|uniprotkb:Scye1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000028029(gene)|ensembl:ENSMUST00000198513(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P31230 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:8fzNg74uhnuVkm2zNOuQMTIIjVc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:A2AN08 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285947|uniprotkb:A2AN07|uniprotkb:A2AN09|uniprotkb:A2AN10|uniprotkb:A2AN11|uniprotkb:Q52KI4|uniprotkb:Q6PB49|uniprotkb:Q6PFC7|uniprotkb:Q80Y11|uniprotkb:Q8BGB9|uniprotkb:Q8C3E8|uniprotkb:Q8C4W5|uniprotkb:Q8C8X7|uniprotkb:Q8CGE0|uniprotkb:Q8CHF3|ensembl:ENSMUSP00000095433 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ubr4_mouse(display_long)|uniprotkb:Kiaa0462(gene name synonym)|uniprotkb:Zubr1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Ubr4(gene name)|psi-mi:Ubr4(display_short)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:p600(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001153791.1|dip:DIP-61499N|ensembl:ENSMUSG00000066036(gene)|ensembl:ENSMUST00000097822(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:A2AN08|reactome:R-MMU-6798695|reactome:R-MMU-983168|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:dTpQoZkH0+rwfrguOvzwrbPh0+Y10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P63017 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q922D4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286373|uniprotkb:Q6ZPM9|uniprotkb:Q8BTW6|uniprotkb:Q9D2X9|ensembl:ENSMUSP00000025846 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pp6r3_mouse(display_long)|uniprotkb:Ppp6r3(gene name)|psi-mi:Ppp6r3(display_short)|uniprotkb:D19Ertd703e(gene name synonym)|uniprotkb:Kiaa1558(gene name synonym)|uniprotkb:Pp6r3(gene name synonym)|uniprotkb:Saps3(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001157631.1|refseq:NP_083275.1|refseq:NP_083732.1|ensembl:ENSMUSG00000024908(gene)|ensembl:ENSMUST00000025846(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q922D4|reactome:R-MMU-171319|reactome:R-MMU-204005|refseq:XP_006531859.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:cfyYAB9Ybqu8fRU64DNvVMI6zOE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q80TP3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2553642|uniprotkb:Q810V6|uniprotkb:Q698K9|uniprotkb:Q9CXE9|uniprotkb:Q6PFQ9|uniprotkb:Q80VL4|uniprotkb:Q6PEQ8 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ubr5_mouse(display_long)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)|uniprotkb:Edd(gene name synonym)|uniprotkb:Edd1(gene name synonym)|uniprotkb:Kiaa0896(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001074828.2|refseq:NP_001106192.1|dip:DIP-56890N|mint:Q80TP3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:iUtn1CtWFtqWQV3UH06xJ5R5Ux010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9WU62 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2552254|ensembl:ENSMUSP00000157547|uniprotkb:Q7TN28|uniprotkb:Q8BGN4|uniprotkb:Q8CGI4 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ince_mouse(display_long)|uniprotkb:Incenp(gene name)|psi-mi:Incenp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000024660(gene)|ensembl:ENSMUST00000237439(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000801"(central element)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0010369"(chromocenter)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR005635(Inner centromere protein, ARK binding region)|interpro:IPR022006|interpro:IPR039130|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-4615885|refseq:NP_057901.2|refseq:XP_006526775.1|dip:DIP-56678N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:N6xAW1cjjPuPqyDHyDde4vbRkAQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91VI7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285005|uniprotkb:Q924P4|ensembl:ENSMUSP00000101651|ensembl:ENSMUSP00000133061 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rini_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Rnh(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001165571.1|refseq:NP_001165572.1|refseq:NP_660117.2|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR041302|mint:Q91VI7|rcsb pdb:3TSR|ensembl:ENSMUSG00000038650(gene)|ensembl:ENSMUST00000106033(transcript)|ensembl:ENSMUST00000167493(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:22sdTjNahBoEuq/md/5/amFIPeM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O35737 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299747|ensembl:ENSMUSP00000070503|ensembl:ENSMUSP00000104770 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hnrh1_mouse(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Hnrph(gene name synonym)|uniprotkb:Hnrph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000007850(gene)|ensembl:ENSMUST00000069304(transcript)|ensembl:ENSMUST00000109142(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:O35737|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:NP_067485.1|refseq:XP_017170179.1|refseq:XP_017170180.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:nBSCiXDDfkwqslFAXPXlDzC+5e410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:A2ARV4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-300875|uniprotkb:P70215|uniprotkb:Q3TL35|uniprotkb:Q9JLB3|ensembl:ENSMUSP00000079752 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:lrp2_mouse(display_long)|uniprotkb:Lrp2(gene name)|psi-mi:Lrp2(display_short)|uniprotkb:Megalin(gene name synonym)|uniprotkb:Glycoprotein 330(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046879"(hormone secretion)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060068"(vagina development)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140058"(neuron projection arborization)|go:"GO:0140077"(positive regulation of lipoprotein transport)|go:"GO:0140318"(protein transporter activity)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006766"(vitamin metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0020028"(endocytic hemoglobin import into cell)|go:"GO:0030001"(metal ion transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031526"(brush border membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035904"(aorta development)|go:"GO:0042562"(hormone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044321"(response to leptin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|ensembl:ENSMUSG00000027070(gene)|ensembl:ENSMUST00000080953(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|mint:A2ARV4|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-975634|refseq:NP_001074557.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:daFSvi86EGJc3bNtEUmoED10K6o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91VM3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286281|uniprotkb:A2AEV3|uniprotkb:A2AEV4|uniprotkb:Q9CVF7|uniprotkb:Q9JIG9|ensembl:ENSMUSP00000041456|ensembl:ENSMUSP00000111351|ensembl:ENSMUSP00000111353 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:wipi4_mouse(display_long)|uniprotkb:Wdr45(gene name)|psi-mi:Wdr45(display_short)|uniprotkb:DXImx38e(gene name synonym)|uniprotkb:Wdrx1(gene name synonym)|uniprotkb:Wipi4(gene name synonym)|uniprotkb:WD repeat domain X-linked 1(gene name synonym)|uniprotkb:WD repeat-containing protein 45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_758960.1|refseq:NP_001277721.1|refseq:NP_001277723.1|refseq:NP_001277724.1|ensembl:ENSMUSG00000039382(gene)|ensembl:ENSMUST00000043045(transcript)|ensembl:ENSMUST00000115687(transcript)|ensembl:ENSMUST00000115689(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032910|interpro:IPR036322|reactome:R-MMU-1632852|go:"GO:0000045"(autophagosome assembly)|refseq:XP_006527719.1|refseq:XP_017174050.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:xPXqYdsOL/Y7hPJh8/uhIvSP5RA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9ERD7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8C854 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285350|uniprotkb:Q6ZPT3|uniprotkb:Q8QZZ1|uniprotkb:Q60690|uniprotkb:Q6P930|ensembl:ENSMUSP00000123088 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:myef2_mouse(display_long)|uniprotkb:Myef2(gene name)|psi-mi:Myef2(display_short)|uniprotkb:Kiaa1341(gene name synonym)|uniprotkb:Mef2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001155889.1|refseq:XP_006498947.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1)|mint:Q8C854|ensembl:ENSMUSG00000027201(gene)|ensembl:ENSMUST00000152367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|refseq:XP_017171620.1|refseq:XP_017171621.1|refseq:XP_017171623.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ZnM8NqQUhlLdO7gzhs09ckrZUPw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q99KJ8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-776048|ensembl:ENSMUSP00000026479 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dctn2_mouse(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:Growth cone membrane protein 23-48K(gene name synonym)|uniprotkb:Dctn2(gene name)|psi-mi:Dctn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_081427.1|ensembl:ENSMUSG00000025410(gene)|ensembl:ENSMUST00000026479(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q99KJ8|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:D7u4MT5Zl5mRBQ/zsTwhYP0WHoU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CQN1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286155|uniprotkb:Q542I4|ensembl:ENSMUSP00000006137 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:trap1_mouse(display_long)|uniprotkb:Trap1(gene name)|psi-mi:Trap1(display_short)|uniprotkb:Hsp75(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080784.1|ensembl:ENSMUSG00000005981(gene)|ensembl:ENSMUST00000006137(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q9CQN1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:8DL4FdXZj8opXUye3mhVpcHjbdU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8R3Q2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285597|uniprotkb:Q9CXB7 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pp6r2_mouse(display_long)|uniprotkb:Ppp6r2(gene name)|psi-mi:Ppp6r2(display_short)|uniprotkb:Kiaa0685(gene name synonym)|uniprotkb:Pp6r2(gene name synonym)|uniprotkb:Saps2(gene name synonym)|uniprotkb:SAPS domain family member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 mint:Q8R3Q2|interpro:IPR007587(SIT4 phosphatase-associated protein)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR016024(Armadillo-type fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:NKhCFgctjoEdJxqAxzU6GnXg4iQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q80SU7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286311|uniprotkb:Q3U3F2|uniprotkb:Q8BL18|uniprotkb:Q8CBA9|ensembl:ENSMUSP00000102377|ensembl:ENSMUSP00000135898 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:gvin1_mouse(display_long)|uniprotkb:Gvin1(gene name)|psi-mi:Gvin1(display_short)|uniprotkb:Very large-inducible GTPase-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001229968.1|refseq:NP_001229969.1|ensembl:ENSMUSG00000078606(gene)|ensembl:ENSMUST00000106766(transcript)|ensembl:ENSMUST00000176467(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|interpro:IPR027417|interpro:IPR029028|interpro:IPR030383|refseq:XP_017177385.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:c/yp0GdfvR786D+mqsLpP5scZNs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D0B8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285525|uniprotkb:Q9CS97|ensembl:ENSMUSP00000026288 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ribc1_mouse(display_long)|uniprotkb:Ribc1(gene name)|psi-mi:Ribc1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_079936.1|ensembl:ENSMUSG00000025257(gene)|ensembl:ENSMUST00000026288(transcript)|interpro:IPR008805(RIB43A)|refseq:XP_006529028.1|refseq:XP_006529029.1|refseq:XP_006529030.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:CRu9+98v4cUamS7yLacLVbOQHFA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P80313 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-309306|ensembl:ENSMUSP00000032078 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcph_mouse(display_long)|uniprotkb:Cct7(gene name)|psi-mi:Cct7(display_short)|uniprotkb:Ccth(gene name synonym)|uniprotkb:CCT-eta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031664.3|ensembl:ENSMUSG00000030007(gene)|ensembl:ENSMUST00000032078(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80313|reactome:R-MMU-390471|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ds2hAlDoiHN/urDfVMjJhNumSqo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P61979 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299907|ensembl:ENSMUSP00000039269|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q8BGQ8|uniprotkb:Q922Y7|uniprotkb:Q96J62 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hnrpk_mouse(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUST00000043269(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000021546(gene)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61979|reactome:R-MMU-4570464|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|refseq:NP_001288269.1|refseq:NP_001288270.1|refseq:NP_001288272.1|refseq:NP_001288273.1|refseq:NP_001288274.1|refseq:XP_017170884.1|refseq:XP_017170885.1|refseq:NP_079555.1|refseq:XP_006517166.1|refseq:XP_006517167.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P68369 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BHM7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285994|uniprotkb:Q6PDC4|ensembl:ENSMUSP00000070685 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q8bhm7_mouse(display_long)|uniprotkb:Zfp747(gene name)|psi-mi:Zfp747(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_780769.1|ensembl:ENSMUSG00000054381(gene)|ensembl:ENSMUST00000067425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:GEEMNQMfbG4nj0Qjg3QmdPldhfQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9EP71 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91V41 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-3869482|ensembl:ENSMUSP00000028238 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rab14_mouse(display_long)|uniprotkb:Rab14(gene name)|psi-mi:Rab14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080973.1|ensembl:ENSMUST00000028238(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:Q91V41|reactome:R-MMU-1660499|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198|ensembl:ENSMUSG00000026878(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9EQ51 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284749|uniprotkb:Q2M2P9|uniprotkb:Q8VIC8 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:v1r47_mouse(display_long)|uniprotkb:Vomeronasal type-1 receptor A4(gene name synonym)|uniprotkb:Vmn1r47(gene name)|psi-mi:Vmn1r47(display_short)|uniprotkb:V1ra4(gene name synonym)|uniprotkb:V1ra7(gene name synonym)|uniprotkb:Vomeronasal type-1 receptor A7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_444449.2|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR004072(Vomeronasal receptor, type 1)|go:"GO:0005886"(plasma membrane)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016503"(pheromone receptor activity)|go:"GO:0019236"(response to pheromone) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:n/OhiZ+DkhJ7PSeLHvQPWSOWD0I10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P56959 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-400452|ensembl:ENSMUSP00000101858 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:fus_mouse(display_long)|uniprotkb:Fus(gene name)|psi-mi:Fus(display_short)|uniprotkb:Protein pigpen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_631888.1|ensembl:ENSMUSG00000030795(gene)|ensembl:ENSMUST00000106251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P56959|reactome:R-MMU-72163 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Vwv/0vlM50l49XaUOHCtEWt/b2A10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q71LX8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2657945 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CXF4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-688073|uniprotkb:Q3UI41|ensembl:ENSMUSP00000020339 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tbc15_mouse(display_long)|uniprotkb:Tbc1d15(gene name)|psi-mi:Tbc1d15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_079982.3|ensembl:ENSMUSG00000020130(gene)|ensembl:ENSMUST00000020339(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-MMU-8854214 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:L0/dKYoB1DP62jpikABtqE/e5hM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P20029 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q7TMY7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-529682|uniprotkb:Q811I3|uniprotkb:Q8C8A9|uniprotkb:Q8R2P6|uniprotkb:Q8R3V7|uniprotkb:B2KGD8|ensembl:ENSMUSP00000046759 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ipo8_mouse(display_long)|uniprotkb:Ran-binding protein 8(gene name synonym)|uniprotkb:Ipo8(gene name)|psi-mi:Ipo8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001074582.1|ensembl:ENSMUSG00000040029(gene)|ensembl:ENSMUST00000048418(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-5578749 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:t66sJspmOc0nPVo2op5I0qLIGCk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q7TSI3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286465|uniprotkb:Q80TJ4|ensembl:ENSMUSP00000066736 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pp6r1_mouse(display_long)|uniprotkb:Ppp6r1(gene name)|psi-mi:Ppp6r1(display_short)|uniprotkb:Kiaa1115(gene name synonym)|uniprotkb:Pp6r1(gene name synonym)|uniprotkb:Saps1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_766482.2|refseq:XP_011248858.1|ensembl:ENSMUSG00000052296(gene)|ensembl:ENSMUST00000064099(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-204005 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ET7IE429eaRNAHpRwjds5XF7nrA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BTI7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285791|uniprotkb:Q148Z3|ensembl:ENSMUSP00000014642 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:anr52_mouse(display_long)|uniprotkb:Ankrd52(gene name)|psi-mi:Ankrd52(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000014498(gene)|ensembl:ENSMUST00000014642(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_766378.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:SEquz8q6kwYH2FL3ociibMNZ2+A10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3TRG2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286067 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3trg2_mouse(display_long)|uniprotkb:Map3k20(gene name)|psi-mi:Map3k20(display_short)|uniprotkb:B230120H23Rik(gene name synonym)|uniprotkb:Zak(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:NP_001158263.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:eSsUpnkFXjLCJdeTJARDXSYhD3U10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6QI06 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286572|uniprotkb:Q0VAV4|uniprotkb:Q69Z40|uniprotkb:Q6PDL2|uniprotkb:Q6RI74|uniprotkb:Q8BPH9|uniprotkb:Q8CBF2|uniprotkb:E9QPE0|ensembl:ENSMUSP00000051809 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rictr_mouse(display_long)|uniprotkb:Rictor(gene name)|psi-mi:Rictor(display_short)|uniprotkb:Kiaa1999(gene name synonym)|uniprotkb:AVO3 homolog(gene name synonym)|uniprotkb:Protein pianissimo(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_084444.3|ensembl:ENSMUSG00000050310(gene)|ensembl:ENSMUST00000061656(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0043022"(ribosome binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR028267|go:"GO:0051896"(regulation of protein kinase B signaling)|interpro:IPR028268|interpro:IPR029259|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|mint:Q6QI06|reactome:R-MMU-1257604|reactome:R-MMU-389357|reactome:R-MMU-5218920|reactome:R-MMU-6804757|dip:DIP-46323N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:kGw85Mzrcf/GOwtH+hxksacjdUk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14602 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299023|ensembl:ENSMUSP00000005077 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q61545 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q66JY6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285551|uniprotkb:A2AIN0|uniprotkb:Q3TQV6|ensembl:ENSMUSP00000055293 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:arg39_mouse(display_long)|uniprotkb:Arhgef39(gene name)|psi-mi:Arhgef39(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001013395.2|ensembl:ENSMUSG00000051517(gene)|ensembl:ENSMUST00000054538(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR042987|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-9013149|refseq:XP_006537893.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:T/2Qtrf5jI6R1e8MGLWPEd/H7F010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P26039 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1039593|uniprotkb:Q8VEF0|uniprotkb:A2AIM8|ensembl:ENSMUSP00000030187 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tln1_mouse(display_long)|uniprotkb:Tln1(gene name)|psi-mi:Tln1(display_short)|uniprotkb:Tln(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035732.2|refseq:XP_006537832.2|ensembl:ENSMUSG00000028465(gene)|ensembl:ENSMUST00000030187(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:P26039|rcsb pdb:1SJ7|rcsb pdb:1SJ8|rcsb pdb:1T01|rcsb pdb:1U89|rcsb pdb:1XWX|rcsb pdb:1Y19|rcsb pdb:1ZW3|rcsb pdb:2B0H|rcsb pdb:2G35|rcsb pdb:2JSW|rcsb pdb:2KBB|rcsb pdb:2KC1|rcsb pdb:2KC2|rcsb pdb:2KGX|rcsb pdb:2KMA|rcsb pdb:2KVP|rcsb pdb:2L10|rcsb pdb:2L7A|rcsb pdb:2L7N|rcsb pdb:2LQG|rcsb pdb:2QDQ|rcsb pdb:2X0C|rcsb pdb:3DYJ|rcsb pdb:3IVF|rcsb pdb:3S90|rcsb pdb:4F7G|rcsb pdb:4W8P|rcsb pdb:5FZT|rcsb pdb:5IC0|rcsb pdb:5IC1|rcsb pdb:5NL1|rcsb pdb:6BA6|rcsb pdb:6MFS|rcsb pdb:6TWN|rcsb pdb:6VGU|reactome:R-MMU-114608|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-399955|reactome:R-MMU-445355|reactome:R-MMU-5674135|dip:DIP-647N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:w9NQrwqUcuVAzeesymnTmhrEtCk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91YE6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-529907|uniprotkb:Q924M3|uniprotkb:Q924M4 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ipo9_mouse(display_long)|uniprotkb:Importin-9a(gene name synonym)|uniprotkb:Importin-9b(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)|uniprotkb:Ipo9(gene name)|psi-mi:Ipo9(display_short)|uniprotkb:Imp9(gene name synonym)|uniprotkb:Ranbp9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 dip:DIP-34268N|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:pLLwywwG94FG4WvewQvoebF1HP410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O54916 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-642662|uniprotkb:Q8C9J9|uniprotkb:Q99LR8|uniprotkb:Q3UAM3|uniprotkb:Q5PPQ9|ensembl:ENSMUSP00000123238 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:reps1_mouse(display_long)|uniprotkb:RalBP1-interacting protein 1(gene name synonym)|uniprotkb:Reps1(gene name)|psi-mi:Reps1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001104535.1|refseq:NP_033074.2|ensembl:ENSMUSG00000019854(gene)|ensembl:ENSMUST00000126390(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:O54916|rcsb pdb:1FI6|reactome:R-MMU-8856825|reactome:R-MMU-8856828 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:SUnawYEyzAOseTj6bNkzh2QPfGA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3UBU0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284683 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q3ubu0_mouse(display_long)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Tra1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0042470"(melanosome)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:PhxqxH6PhxU2iIAtErIyQ0pZ5ro10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P70168 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-540580|uniprotkb:Q62117|uniprotkb:Q6GTI5|ensembl:ENSMUSP00000001479 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:imb1_mouse(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:SCG(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Impnb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032405.3|ensembl:ENSMUSG00000001440(gene)|ensembl:ENSMUST00000001479(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|reactome:R-MMU-2995383|reactome:R-MMU-6798695|reactome:R-MMU-909733|reactome:R-MMU-1655829|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:P70168|rcsb pdb:1GCJ|rcsb pdb:1UKL|go:"GO:0019894"(kinesin binding)|reactome:R-MMU-140342|dip:DIP-33404N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:rYDCcZYUZp8TbcpyJE7pfz5+bvo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P68368 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q505D1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286346|ensembl:ENSMUSP00000014640 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:anr28_mouse(display_long)|uniprotkb:Ankrd28(gene name)|psi-mi:Ankrd28(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001019775.1|ensembl:ENSMUSG00000014496(gene)|ensembl:ENSMUST00000014640(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-MMU-171319|reactome:R-MMU-204005 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:jhZYM9tAWCCd4hV3c/YAyNi0Y3s10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D2M8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-911251|uniprotkb:Q8BGH6|uniprotkb:Q8CE99|uniprotkb:Q8K2V7|uniprotkb:Q9CYD7|uniprotkb:Q9ERI8|uniprotkb:A6X924|ensembl:ENSMUSP00000111443 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ub2v2_mouse(display_long)|uniprotkb:Ubc-like protein MMS2(gene name synonym)|uniprotkb:Ube2v2(gene name)|psi-mi:Ube2v2(display_short)|uniprotkb:Mms2(gene name synonym)|uniprotkb:Uev2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001152823.1|refseq:NP_076074.2|ensembl:ENSMUSG00000022674(gene)|ensembl:ENSMUST00000115777(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9D2M8|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-69473|reactome:R-MMU-8866654|reactome:R-MMU-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:nY0ENcwjbooLvqOoe1NdM4Dp4J410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D8E6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773932|uniprotkb:Q9CY08|ensembl:ENSMUSP00000034966 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl4_mouse(display_long)|uniprotkb:Rpl4(gene name)|psi-mi:Rpl4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_077174.1|ensembl:ENSMUSG00000032399(gene)|ensembl:ENSMUST00000034966(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR023574|interpro:IPR025755|mint:Q9D8E6|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qAUdFzxz+ZWX98r7PxtHQGtTXKw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P60122 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1634999|uniprotkb:O35753|ensembl:ENSMUSP00000032165 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ruvb1_mouse(display_long)|uniprotkb:Ruvbl1(gene name)|psi-mi:Ruvbl1(display_short)|uniprotkb:Tip49(gene name synonym)|uniprotkb:Tip49a(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:DNA helicase p50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062659.1|ensembl:ENSMUSG00000030079(gene)|ensembl:ENSMUST00000032165(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:P60122|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5696394|reactome:R-MMU-606279 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:fZiQ7AurvKII0LYc+haBswAXfZ410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P07901 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P80314 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P38647 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P05213 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9CQR6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286534|uniprotkb:A2ASL7|ensembl:ENSMUSP00000028087 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ppp6_mouse(display_long)|uniprotkb:Ppp6c(gene name)|psi-mi:Ppp6c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_077171.1|ensembl:ENSMUSG00000026753(gene)|ensembl:ENSMUST00000028087(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:Q9CQR6|reactome:R-MMU-171319|reactome:R-MMU-204005|go:"GO:0006470"(protein dephosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:R0jsZoqJLoRaSNMNCLRkQ40CC+o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P47911 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773947|uniprotkb:Q6P5I2|uniprotkb:Q925C3|ensembl:ENSMUSP00000031617 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl6_mouse(display_long)|uniprotkb:TAX-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Rpl6(gene name)|psi-mi:Rpl6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035420.2|refseq:XP_006530290.1|ensembl:ENSMUSG00000029614(gene)|ensembl:ENSMUST00000031617(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:P47911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:rm/g3X/3zoauNoUW6K4M43n8e4810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62991 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BW10 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285326|uniprotkb:Q7TPR3|uniprotkb:Q9CRD7|ensembl:ENSMUSP00000003946 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nob1_mouse(display_long)|uniprotkb:Nob1(gene name)|psi-mi:Nob1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080553.1|ensembl:ENSMUSG00000003848(gene)|ensembl:ENSMUST00000003946(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0007601"(visual perception)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR014881("Nin one binding (NOB1) Zn-ribbon like")|interpro:IPR017117(D-site 20S pre-rRNA nuclease)|interpro:IPR033411|interpro:IPR033461|interpro:IPR036283|interpro:IPR039907|mint:Q8BW10|rcsb pdb:2CON|reactome:R-MMU-6791226|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:4FSF629OjIWA4JJM1shkYB+O8aQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P02089 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-494213|uniprotkb:Q5D0E8 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hbb2_mouse(display_long)|uniprotkb:Hemoglobin beta-2 chain(gene name synonym)|uniprotkb:Beta-2-globin(gene name synonym)|uniprotkb:Hemoglobin beta-minor chain(gene name synonym)|uniprotkb:Hbb-b2(gene name)|psi-mi:Hbb-b2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|refseq:NP_058652.1|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|rcsb pdb:1FNE|rcsb pdb:1FNG|rcsb pdb:1I3R|mint:P02089 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:5t7MUKklDto4E5kgtOvSP8i82vU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P11983 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772338|uniprotkb:Q3TJ96|uniprotkb:Q3TKU1|uniprotkb:Q3U5T8|uniprotkb:Q3U7I8|uniprotkb:Q3UAA8|uniprotkb:Q3UB80|uniprotkb:Q3UE48|intact:EBI-2291308|uniprotkb:P11984|ensembl:ENSMUSP00000116108 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpa_mouse(display_long)|uniprotkb:CCT-alpha(gene name synonym)|uniprotkb:Tailless complex polypeptide 1B(gene name synonym)|uniprotkb:Tcp1(gene name)|psi-mi:Tcp1(display_short)|uniprotkb:Ccta(gene name synonym)|uniprotkb:Cct1(gene name synonym)|uniprotkb:Tailless complex polypeptide 1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001277641.1|refseq:NP_038714.2|dip:DIP-32342N|ensembl:ENSMUSG00000068039(gene)|ensembl:ENSMUST00000151287(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P11983|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:mSINCow3H5FzUCTXpqwkI18OI9o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91WG2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286011|uniprotkb:Q3UMK8|uniprotkb:Q99KN3|ensembl:ENSMUSP00000102015 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rabe2_mouse(display_long)|uniprotkb:Rabep2(gene name)|psi-mi:Rabep2(display_short)|uniprotkb:Rabpt5b(gene name synonym)|uniprotkb:Rabaptin-5beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_085043.2|ensembl:ENSMUSG00000030727(gene)|ensembl:ENSMUST00000106407(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005769"(early endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008083"(growth factor activity)|go:"GO:0015031"(protein transport)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|interpro:IPR029882 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:XFKyv669pq/6BsFIQfNzX/E1ntg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9EPL8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2550269|ensembl:ENSMUSP00000081782|uniprotkb:Q7TN09|uniprotkb:Q7TQ63|uniprotkb:Q8BKD8|uniprotkb:Q8BYI0 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ipo7_mouse(display_long)|uniprotkb:Ipo7(gene name)|psi-mi:Ipo7(display_short)|uniprotkb:Ranbp7(gene name synonym)|uniprotkb:Ran-binding protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000066232(gene)|ensembl:ENSMUST00000084731(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9EPL8|refseq:NP_852658.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:YOGtbOzeE6Oq5T0J42GWW7fH9H010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8C7U1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285266|uniprotkb:A2AA64|uniprotkb:Q3TDC7|uniprotkb:Q3URT6|uniprotkb:Q7TNR2|uniprotkb:Q922W0|uniprotkb:Q99J06|ensembl:ENSMUSP00000001080 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:n4bp3_mouse(display_long)|uniprotkb:N4bp3(gene name)|psi-mi:N4bp3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_666086.2|refseq:XP_006532827.1|refseq:XP_006532828.1|refseq:XP_006532829.1|ensembl:ENSMUSG00000001053(gene)|ensembl:ENSMUST00000001080(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR033571 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Ajjfol67/dYOs6FMEXT865zh2+c10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P16858 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q5NCC3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285242|ensembl:ENSMUSP00000037055 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tri41_mouse(display_long)|uniprotkb:Trim41(gene name)|psi-mi:Trim41(display_short)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_663352.2|ensembl:ENSMUSG00000040365(gene)|ensembl:ENSMUST00000047145(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|reactome:R-MMU-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:uPAudDatI84CCp2/lR51w1zHLyo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q99M87 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-647233|uniprotkb:Q8BSM0|uniprotkb:Q99L09|uniprotkb:Q99P71|uniprotkb:Q99P76|uniprotkb:Q9CT11|uniprotkb:Q9DBJ7|uniprotkb:Q9DC44|ensembl:ENSMUSP00000053842 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dnja3_mouse(display_long)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Dnaja3(gene name)|psi-mi:Dnaja3(display_short)|uniprotkb:Tid1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001128584.1|refseq:NP_076135.3|mint:Q99M87|ensembl:ENSMUSG00000004069(gene)|ensembl:ENSMUST00000060067(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:dBJIJ2BY9vghCDt8+ooQWBFjsRs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9JHU4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14152 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-494462|uniprotkb:Q3TP22|uniprotkb:Q80Y13|uniprotkb:Q9DB45|ensembl:ENSMUSP00000099938|ensembl:ENSMUSP00000159017 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:mdhc_mouse(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:Mdh1(gene name)|psi-mi:Mdh1(display_short)|uniprotkb:Mor2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032644.3|refseq:NP_001303604.1|ensembl:ENSMUSG00000020321(gene)|ensembl:ENSMUST00000102874(transcript)|ensembl:ENSMUST00000239073(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016615"(malate dehydrogenase activity)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010945(Malate dehydrogenase, NAD or NADP)|interpro:IPR011274(Malate dehydrogenase, NAD-dependent, cytosolic)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|go:"GO:0006108"(malate metabolic process)|interpro:IPR022383|interpro:IPR036291|mint:P14152|reactome:R-MMU-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Yq74ALpVIoaMM9Y2LUS4Sdmfztg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P67871 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-348179|ensembl:ENSMUSP00000025246|ensembl:ENSMUSP00000134218|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q3TTJ7 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:csk2b_mouse(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Csnk2b(gene name)|psi-mi:Csnk2b(display_short)|uniprotkb:Ck2n(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000024387(gene)|ensembl:ENSMUST00000025246(transcript)|ensembl:ENSMUST00000173114(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67871|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6798695|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751|refseq:NP_034105.1|refseq:NP_001290374.1|dip:DIP-35573N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9DC22 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285627|uniprotkb:Q8BK50|ensembl:ENSMUSP00000027856 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dcaf6_mouse(display_long)|uniprotkb:Dcaf6(gene name)|psi-mi:Dcaf6(display_short)|uniprotkb:Iqwd1(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_083035.1|ensembl:ENSMUSG00000026571(gene)|ensembl:ENSMUST00000027856(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-MMU-8951664 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:64fGm21LpOKRoZRMJn9S5pe3yxE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P29341 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773902|uniprotkb:Q99L36|ensembl:ENSMUSP00000001809 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pabp1_mouse(display_long)|uniprotkb:Pabpc1(gene name)|psi-mi:Pabpc1(display_short)|uniprotkb:Pabp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 dip:DIP-32127N|refseq:NP_032800.2|refseq:XP_011243641.1|ensembl:ENSMUSG00000022283(gene)|ensembl:ENSMUST00000001809(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045202"(synapse)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P29341|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:jvlQW6kphF2tkZwK72DtAXDPHvs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BGS1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4283324|uniprotkb:Q3TJG0|uniprotkb:Q69ZG8|uniprotkb:Q8BSC9|uniprotkb:Q99KZ8|ensembl:ENSMUSP00000058966 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:e41l5_mouse(display_long)|uniprotkb:Epb4.1l5(gene name synonym)|uniprotkb:Kiaa1548(gene name synonym)|uniprotkb:Epb41l5(gene name)|psi-mi:Epb41l5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0001756"(somitogenesis)|refseq:NP_001106887.1|refseq:NP_663481.2|refseq:XP_006529460.1|refseq:XP_006529461.1|refseq:XP_006529463.1|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0048319"(axial mesoderm morphogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|ensembl:ENSMUSG00000026383(gene)|ensembl:ENSMUST00000052404(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|interpro:IPR030694|mint:Q8BGS1|reactome:R-MMU-6794361|interpro:IPR035963 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:pt6yMNx5+txA950Eal6TthTO5sM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P09528 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-308950|uniprotkb:Q3UI44|ensembl:ENSMUSP00000025563|ensembl:ENSMUSP00000158539 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:frih_mouse(display_long)|uniprotkb:Fth1(gene name)|psi-mi:Fth1(display_short)|uniprotkb:Fth(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034369.1|ensembl:ENSMUSG00000024661(gene)|ensembl:ENSMUST00000025563(transcript)|ensembl:ENSMUST00000235196(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|mint:P09528|rcsb pdb:3WNW|go:"GO:0008285"(negative regulation of cell population proliferation)|rcsb pdb:5OBA|go:"GO:0044754"(autolysosome)|rcsb pdb:5OBB|go:"GO:0048147"(negative regulation of fibroblast proliferation)|rcsb pdb:6S61|rcsb pdb:6SHT|rcsb pdb:6V21|rcsb pdb:7A4M|rcsb pdb:7KOD|go:"GO:0071682"(endocytic vesicle lumen)|reactome:R-MMU-432722|reactome:R-MMU-6798695|reactome:R-MMU-917937|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:dg7aqsV02liocLxEKKesIMGxyWs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9JJI8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286104|ensembl:ENSMUSP00000080741|ensembl:ENSMUSP00000102209|ensembl:ENSMUSP00000102211|ensembl:ENSMUSP00000102213 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl38_mouse(display_long)|uniprotkb:Rpl38(gene name)|psi-mi:Rpl38(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001041522.1|refseq:NP_001041523.1|refseq:NP_075861.1|refseq:XP_006534072.1|go:"GO:0033291"(eukaryotic 80S initiation complex)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0048318"(axial mesoderm development)|interpro:IPR002675(Ribosomal protein L38e)|interpro:IPR038464|mint:Q9JJI8|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)|refseq:XP_017170209.1|ensembl:ENSMUSG00000057322(gene)|ensembl:ENSMUST00000077915(transcript)|ensembl:ENSMUST00000082092(transcript)|ensembl:ENSMUST00000106599(transcript)|ensembl:ENSMUST00000106602(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022618"(ribonucleoprotein complex assembly)|go:"GO:0022625"(cytosolic large ribosomal subunit) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:rs3Syk5fg3yYGcZm6oXRx/ORc2Q10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9Z2V5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1009256|uniprotkb:B1AUA6|ensembl:ENSMUSP00000033501|ensembl:ENSMUSP00000111306 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hdac6_mouse(display_long)|uniprotkb:Histone deacetylase mHDA2(gene name synonym)|uniprotkb:Hdac6(gene name)|psi-mi:Hdac6(display_short)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001123888.1|refseq:NP_034543.3|ensembl:ENSMUSG00000031161(gene)|ensembl:ENSMUST00000033501(transcript)|ensembl:ENSMUST00000115642(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005901"(caveola)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0030424"(axon)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3371511|reactome:R-MMU-350054|reactome:R-MMU-5617833|reactome:R-MMU-9646399|refseq:XP_006527630.1|refseq:XP_017173877.1|refseq:XP_017173878.1|dip:DIP-36461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:nvUUsssLQM03b2wLNbk7eb/5SxM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BIL5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285715|uniprotkb:Q8BIZ2|uniprotkb:Q8K0P1|uniprotkb:Q8K454|uniprotkb:Q9CTN6|ensembl:ENSMUSP00000030306 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hook1_mouse(display_long)|uniprotkb:Hook1(gene name)|psi-mi:Hook1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_084290.1|ensembl:ENSMUSG00000028572(gene)|ensembl:ENSMUST00000030306(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007286"(spermatid development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0030897"(HOPS complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|rcsb pdb:1WIX psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:9TPq3L1452DU5WxJT8JGhHpHwOY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D8N0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P42932 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772400|ensembl:ENSMUSP00000026704 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpq_mouse(display_long)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Cct8(gene name)|psi-mi:Cct8(display_short)|uniprotkb:Cctq(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033970.3|ensembl:ENSMUSG00000025613(gene)|ensembl:ENSMUST00000026704(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P42932|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:p3GMjguKvbAdbh4NkDyU8W4nr1E10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P23927 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BX02 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286428|uniprotkb:Q91Z35|uniprotkb:Q8BLD5|ensembl:ENSMUSP00000034717 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:kank2_mouse(display_long)|uniprotkb:Kank2(gene name)|psi-mi:Kank2(display_short)|uniprotkb:Ankrd25(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_663586.3|ensembl:ENSMUSG00000032194(gene)|ensembl:ENSMUST00000034717(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070563"(negative regulation of vitamin D receptor signaling pathway)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|mint:Q8BX02 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:3gK/EE6Zo5R23a10e9dnUUf2sM410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q64332 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-775668|uniprotkb:Q6NZR0|uniprotkb:Q9QWV7|ensembl:ENSMUSP00000009538 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:syn2_mouse(display_long)|uniprotkb:Synapsin II(gene name synonym)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001104485.1|refseq:NP_038709.1|ensembl:ENSMUSG00000009394(gene)|ensembl:ENSMUST00000009538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028712|mint:Q64332|reactome:R-MMU-181429|reactome:R-MMU-212676 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Y/RYUSlblGo1/3HGeKJmfS5yX+M10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9WV92 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-911885|uniprotkb:Q69ZT8|ensembl:ENSMUSP00000079098|uniprotkb:Q9R102 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:e41l3_mouse(display_long)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Epb41l3(gene name)|psi-mi:Epb41l3(display_short)|uniprotkb:Dal1(gene name synonym)|uniprotkb:Epb4.1l3(gene name synonym)|uniprotkb:Kiaa0987(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000024044(gene)|ensembl:ENSMUST00000080208(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9WV92|reactome:R-MMU-6794361|refseq:NP_038841.1|refseq:XP_011244586.1|refseq:XP_011244591.1|refseq:XP_017172724.1|refseq:XP_017172725.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:51gkxiswTUqQbAUqjGoPthWD7jM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62960 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-529779|uniprotkb:P22568|uniprotkb:P27817|uniprotkb:P43482|ensembl:ENSMUSP00000078589 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ybox1_mouse(display_long)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Ybx1(gene name)|psi-mi:Ybx1(display_short)|uniprotkb:Msy1(gene name synonym)|uniprotkb:Msy-1(gene name synonym)|uniprotkb:Yb1(gene name synonym)|uniprotkb:Nsep1(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035862.2|dip:DIP-34256N|ensembl:ENSMUSG00000028639(gene)|ensembl:ENSMUST00000079644(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P62960|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-9017802|go:"GO:0043025"(neuronal cell body) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:imkViHICtFj/0wQ8IDprza1b43010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q62425 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:E9PVA8 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284669|intact:EBI-6908505|uniprotkb:B2RWW6|ensembl:ENSMUSP00000069432 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:gcn1_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:Gcn1l1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_766307.2|ensembl:ENSMUSG00000041638(gene)|ensembl:ENSMUST00000064454(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:E9PVA8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:KX5ViHlt2ZOUAv/9GRSRAMijpE010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9QYJ3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284863|ensembl:ENSMUSP00000005620 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dnjb1_mouse(display_long)|uniprotkb:Dnajb1(gene name)|psi-mi:Dnajb1(display_short)|uniprotkb:Hsp40(gene name synonym)|uniprotkb:Hspf1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_061278.1|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9QYJ3|reactome:R-MMU-3371453|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-5687128|ensembl:ENSMUSG00000005483(gene)|ensembl:ENSMUST00000005620(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:D8BkB2/XxzbL63Aa3O+V3MWlB4s10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q4VC33 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284643|uniprotkb:Q3TFH0|uniprotkb:Q3U7T6|uniprotkb:Q5XKE6|uniprotkb:Q8BPI3|uniprotkb:Q8BSA1|uniprotkb:Q9JK49|ensembl:ENSMUSP00000110093 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:maea_mouse(display_long)|uniprotkb:Emp(gene name synonym)|uniprotkb:Erythroblast macrophage protein(gene name synonym)|uniprotkb:Maea(gene name)|psi-mi:Maea(display_short)|uniprotkb:Macrophage erythroblast attacher(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_067475.2|ensembl:ENSMUSG00000079562(gene)|ensembl:ENSMUST00000114449(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR027714|interpro:IPR044063 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qnRugS8zeL3J3rhR3couKVVen7Q10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O88487 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-776055|uniprotkb:Q3TGH7|ensembl:ENSMUSP00000080410|ensembl:ENSMUSP00000107766 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dc1i2_mouse(display_long)|uniprotkb:Cytoplasmic dynein intermediate chain 2(gene name synonym)|uniprotkb:Dynein intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:Dync1i2(gene name)|psi-mi:Dync1i2(display_short)|uniprotkb:Dncic2(gene name synonym)|uniprotkb:Dnci2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001185805.1|refseq:NP_001185806.1|refseq:NP_001185807.1|refseq:NP_034194.1|ensembl:ENSMUSG00000027012(gene)|ensembl:ENSMUST00000081710(transcript)|ensembl:ENSMUST00000112138(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0031982"(vesicle)|go:"GO:0036157"(outer dynein arm)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:O88487|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:HNendRwA8vyel0CUvmphdxZ7psk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8K214 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-445955|uniprotkb:Q9JME0|uniprotkb:B1AS51|ensembl:ENSMUSP00000069813|ensembl:ENSMUSP00000101908 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:scmh1_mouse(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:Scmh1(gene name)|psi-mi:Scmh1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001153102.1|refseq:NP_038911.1|refseq:XP_011238853.1|refseq:XP_017175741.1|refseq:XP_017175742.1|dip:DIP-32567N|ensembl:ENSMUSG00000000085(gene)|ensembl:ENSMUST00000064991(transcript)|ensembl:ENSMUST00000106301(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:20uldoox7Vf5O66gpqUPR+nSQiI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6PFY1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286501|uniprotkb:Q8BV86|ensembl:ENSMUSP00000047878 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:fcsd1_mouse(display_long)|uniprotkb:Fchsd1(gene name)|psi-mi:Fchsd1(display_short)|uniprotkb:Protein nervous wreck 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_783615.2|ensembl:ENSMUSG00000038524(gene)|ensembl:ENSMUST00000043437(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008289"(lipid binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042995"(cell projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR034935|interpro:IPR035460|interpro:IPR036028 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:fPdsvGRm3svq2jLmassDTHrD2e810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O54833 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1216452|ensembl:ENSMUSP00000055919|ensembl:ENSMUSP00000148404 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:csk22_mouse(display_long)|uniprotkb:Csnk2a2(gene name)|psi-mi:Csnk2a2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034104.1|ensembl:ENSMUSG00000046707(gene)|ensembl:ENSMUST00000056919(transcript)|ensembl:ENSMUST00000212214(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031519"(PcG protein complex)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O54833|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:6aE12BakwtzXfYRZ4EwCGSG5wBE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P58252 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773856|uniprotkb:Q544E4|ensembl:ENSMUSP00000046101 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ef2_mouse(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031933.1|ensembl:ENSMUSG00000034994(gene)|ensembl:ENSMUST00000047864(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P58252|reactome:R-MMU-156902|reactome:R-MMU-5358493|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:910/vo3IRjcncyPD4f43dPtS83o10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D0E1 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773789|uniprotkb:Q6P1B2|uniprotkb:Q99JQ0|ensembl:ENSMUSP00000120115 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:hnrpm_mouse(display_long)|uniprotkb:Hnrpm(gene name synonym)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001103383.1|refseq:NP_084080.1|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:Q9D0E1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000059208(gene)|ensembl:ENSMUST00000148178(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0048306"(calcium-dependent protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:VpoWJwPx1uDzAsBxM3/TfiCMGok10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P80317 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772389 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tcpz_mouse(display_long)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Cct6a(gene name)|psi-mi:Cct6a(display_short)|uniprotkb:Cct6(gene name synonym)|uniprotkb:Cctz(gene name synonym)|uniprotkb:Cctz1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033968.1|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|mint:P80317|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|reactome:R-MMU-390471|reactome:R-MMU-6814122|reactome:R-MMU-9013418 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:E8vqHRMvDBqKtAu5/6UPh1mSYLw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8VDP4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2931660|ensembl:ENSMUSP00000036924|uniprotkb:Q6PIB1|uniprotkb:Q8BWR5|uniprotkb:Q8C0F0|uniprotkb:Q8R3G6 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ccar2_mouse(display_long)|uniprotkb:Ccar2(gene name)|psi-mi:Ccar2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000033712(gene)|ensembl:ENSMUST00000035612(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR028811|mint:Q8VDP4|reactome:R-MMU-3371453|refseq:NP_666167.3|refseq:XP_006518959.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:4KqmxaC2o3+yWOF9dwQ9kQ7AMqs10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62889 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285659|uniprotkb:P04645|ensembl:ENSMUSP00000009039|ensembl:ENSMUSP00000106014 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl30_mouse(display_long)|uniprotkb:Rpl30(gene name)|psi-mi:Rpl30(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001156957.1|refseq:NP_033109.1|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62889|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000058600(gene)|ensembl:ENSMUST00000009039(transcript)|ensembl:ENSMUST00000079735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:xR9LwYg6N7m9njT1pYumOPKZVu410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9R0L7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285401 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:akp8l_mouse(display_long)|uniprotkb:Akap8l(gene name)|psi-mi:Akap8l(display_short)|uniprotkb:Nakap(gene name synonym)|uniprotkb:Nakap95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR034736|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|mint:Q9R0L7 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:k4vqjb0Ct+MAwtLNb4HzGRodDtI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 intact:EBI-4284952 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 - psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:a2cf96_mouse(display_short)|psi-mi:EBI-4284952(display_long)|uniprotkb:DN-199E5.2-002(orf name)|uniprotkb:Kif1c(gene name)|psi-mi:Kif1c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 uniprotkb:A2CF96(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qXITlfD05kcPQmDykQ8Z8/qCCcw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O08599 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-445322|uniprotkb:A2ARS2|uniprotkb:A2ARS3|uniprotkb:A2ARS4|uniprotkb:Q5WAC6|uniprotkb:Q8VD51|ensembl:ENSMUSP00000052440 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:stxb1_mouse(display_long)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001107041.1|refseq:NP_033321.2|interpro:IPR043127|interpro:IPR043154|mint:O08599|go:"GO:0098794"(postsynapse)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|reactome:R-MMU-181429|reactome:R-MMU-181430|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-888590|ensembl:ENSMUSG00000026797(gene)|ensembl:ENSMUST00000050000(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|dip:DIP-31951N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P68040 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D832 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285818|uniprotkb:Q9D9U2|uniprotkb:Q3TS92|ensembl:ENSMUSP00000029669|ensembl:ENSMUSP00000053916|ensembl:ENSMUSP00000114356 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dnjb4_mouse(display_long)|uniprotkb:Dnajb4(gene name)|psi-mi:Dnajb4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000028035(gene)|ensembl:ENSMUST00000029669(transcript)|ensembl:ENSMUST00000050073(transcript)|ensembl:ENSMUST00000144950(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9D832|refseq:NP_080202.1|refseq:NP_081563.2|refseq:XP_006501983.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:7vvyn2D5dI3mKW5efpnhChyyazQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q923E4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1802585|uniprotkb:Q9QXG8|ensembl:ENSMUSP00000020257|ensembl:ENSMUSP00000112595 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:sir1_mouse(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Sir2l1(gene name synonym)|uniprotkb:SIR2alpha(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_062786.1|dip:DIP-47052N|ensembl:ENSMUSG00000020063(gene)|ensembl:ENSMUST00000020257(transcript)|ensembl:ENSMUST00000120239(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014858"(positive regulation of skeletal muscle cell proliferation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044321"(response to leptin)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0006325"(chromatin organization)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000614"(positive regulation of thyroid-stimulating hormone secretion)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-MMU-3371453|reactome:R-MMU-427359|reactome:R-MMU-9617629 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:oMEdQHMy6vybdgCwbHeo3au9YHc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q99ME9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285566|uniprotkb:Q99K16|uniprotkb:Q99P78|uniprotkb:Q9CT02|ensembl:ENSMUSP00000152412 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:gtpb4_mouse(display_long)|uniprotkb:Gtpbp4(gene name)|psi-mi:Gtpbp4(display_short)|uniprotkb:Crfg(gene name synonym)|uniprotkb:Nog1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_081276.2|ensembl:ENSMUSG00000021149(gene)|ensembl:ENSMUST00000222098(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q99ME9 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:bcJx83SRfrtIzUbasVwCDleHiR010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q91YN9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9Z1X9 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286086|uniprotkb:O70547|uniprotkb:Q9QUK1|uniprotkb:Q9R212|ensembl:ENSMUSP00000000028 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cdc45_mouse(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:Cdc45l(gene name synonym)|uniprotkb:Cdc45l2(gene name synonym)|uniprotkb:PORC-PI-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033992.2|refseq:XP_011244115.1|refseq:XP_006521807.1|ensembl:ENSMUST00000000028(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0036064"(ciliary basal body)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|reactome:R-MMU-176187|reactome:R-MMU-68962|ensembl:ENSMUSG00000000028(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Wzhe8ySAL7uFlRNFWgU3lbhJLVc10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9WUM3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284726|uniprotkb:Q9CVA2|uniprotkb:Q3UEB1|ensembl:ENSMUSP00000008893 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cor1b_mouse(display_long)|uniprotkb:Coro1b(gene name)|psi-mi:Coro1b(display_short)|uniprotkb:Coronin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035908.1|refseq:XP_006531804.1|refseq:XP_006531805.1|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9WUM3|go:"GO:0051015"(actin filament binding)|ensembl:ENSMUSG00000024835(gene)|ensembl:ENSMUST00000008893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:8f/wAw9SFege6L8WkRGpdE73+EE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8K1N2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286174|uniprotkb:Q3TNI3|uniprotkb:Q80Y16|uniprotkb:Q8BKV3|ensembl:ENSMUSP00000046496 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:phlb2_mouse(display_long)|uniprotkb:Ll5b(gene name synonym)|uniprotkb:Protein LL5-beta(gene name synonym)|uniprotkb:Phldb2(gene name)|psi-mi:Phldb2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_700461.2|refseq:NP_001239371.1|ensembl:ENSMUSG00000033149(gene)|ensembl:ENSMUST00000036355(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0031252"(cell leading edge)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045180"(basal cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810|mint:Q8K1N2|go:"GO:0070507"(regulation of microtubule cytoskeleton organization) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:tiMY3xaHNbQUq8Jbxt3d9aiylYU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9D880 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284768|uniprotkb:Q8R3A7|uniprotkb:Q91Z17|ensembl:ENSMUSP00000080614 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tim50_mouse(display_long)|uniprotkb:Timm50(gene name)|psi-mi:Timm50(display_short)|uniprotkb:Tim50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_079892.1|ensembl:ENSMUSG00000003438(gene)|ensembl:ENSMUST00000081946(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|go:"GO:0004725"(protein tyrosine phosphatase activity)|interpro:IPR027111|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:u2gH2R2+fn6jfPSn2yoB02yOW4410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P19096 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773277|uniprotkb:Q6PB72|uniprotkb:Q8C4Z0|uniprotkb:Q9EQR0|uniprotkb:B1ATU8|ensembl:ENSMUSP00000052872 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:fas_mouse(display_long)|uniprotkb:Fasn(gene name)|psi-mi:Fasn(display_short)|uniprotkb:Type I Fatty Acid Synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032014.3|ensembl:ENSMUSG00000025153(gene)|ensembl:ENSMUST00000055655(transcript)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0004312"(fatty acid synthase activity)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0009888"(tissue development)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P19096|rcsb pdb:5MY0|rcsb pdb:5MY2|rcsb pdb:6ROP|reactome:R-MMU-163765|reactome:R-MMU-199220|reactome:R-MMU-75105 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:k+MkpzkPX8N0Diy3ovhliRvu73M10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62751 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286547|uniprotkb:P29316|uniprotkb:P39024|uniprotkb:Q92774|ensembl:ENSMUSP00000099541 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl23a_mouse(display_long)|uniprotkb:Rpl23a(gene name)|psi-mi:Rpl23a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_997406.1|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62751|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000058546(gene)|ensembl:ENSMUST00000102483(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|dip:DIP-59973N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6NSQ7 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285341|uniprotkb:Q9D0F5|ensembl:ENSMUSP00000019950 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ltv1_mouse(display_long)|uniprotkb:Ltv1(gene name)|psi-mi:Ltv1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_852135.1|ensembl:ENSMUSG00000019814(gene)|ensembl:ENSMUST00000019950(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007307(Low temperature viability protein)|reactome:R-MMU-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:sA3lTXSfpu0n+dTRe5R5q3JdbjY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P10126 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3UA06 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-308990|uniprotkb:A0JNT8|uniprotkb:Q05CL4|uniprotkb:Q3UQG6|uniprotkb:Q9CWW8|ensembl:ENSMUSP00000022053 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pch2_mouse(display_long)|uniprotkb:Trip13(gene name)|psi-mi:Trip13(display_short)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Pch2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_081458.1|ensembl:ENSMUSG00000021569(gene)|ensembl:ENSMUST00000022053(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:VyTQoaPmHJT2nvfJdg00WZVnhkI10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P19228 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284550|ensembl:ENSMUSP00000092225 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:casa1_mouse(display_long)|uniprotkb:Csn1s1(gene name)|psi-mi:Csn1s1(display_short)|uniprotkb:Csn1(gene name synonym)|uniprotkb:Csna(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_031810.1|refseq:NP_001272944.1|refseq:NP_001272945.1|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|interpro:IPR001588(Casein, alpha/beta)|interpro:IPR026999|interpro:IPR031305|reactome:R-MMU-5223345|ensembl:ENSMUSG00000070702(gene)|ensembl:ENSMUST00000094641(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:pn5phLyF+1mKkloPqPq1jWz3RN810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q05DU6 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285065 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q05du6_mouse(display_long)|uniprotkb:Kif23(gene name)|psi-mi:Kif23(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR027640|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|go:"GO:0005524"(ATP binding)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:1990939" psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:dBX1Dt5IaF01HpmSNBC9ej6vUGA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8VDD5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O54946 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-642500|uniprotkb:Q3TE94|uniprotkb:Q3U6L0|uniprotkb:Q3UNJ5|uniprotkb:Q3UYT7|uniprotkb:Q99LA5|uniprotkb:Q9QYI9|ensembl:ENSMUSP00000008733 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dnjb6_mouse(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001033029.1|refseq:NP_001120839.1|refseq:NP_035977.2|ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000008733(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O54946|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Snii+B7COng2Zkduai/v24f83bw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q62167 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-773173|uniprotkb:O09060|uniprotkb:O09143|ensembl:ENSMUSP00000000804 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ddx3x_mouse(display_long)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD3(gene name synonym)|uniprotkb:Embryonic RNA helicase(gene name synonym)|uniprotkb:D1Pas1-related sequence 2(gene name synonym)|uniprotkb:Ddx3x(gene name)|psi-mi:Ddx3x(display_short)|uniprotkb:D1Pas1-rs2(gene name synonym)|uniprotkb:Ddx3(gene name synonym)|uniprotkb:Dead3(gene name synonym)|uniprotkb:Erh(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034158.1|ensembl:ENSMUSG00000000787(gene)|ensembl:ENSMUST00000000804(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q62167|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:K7PtRsPpXHni4TU8uzOsr6QaVxA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9JLQ0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P08752 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-771937|uniprotkb:Q3TXK7|uniprotkb:Q6P1C0|ensembl:ENSMUSP00000057543|ensembl:ENSMUSP00000142326 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:gnai2_mouse(display_long)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)|uniprotkb:Gnai2(gene name)|psi-mi:Gnai2(display_short)|uniprotkb:Gnai-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032164.2|refseq:XP_006511700.1|dip:DIP-605N|ensembl:ENSMUSG00000032562(gene)|ensembl:ENSMUST00000055704(transcript)|ensembl:ENSMUST00000192615(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P08752|reactome:R-MMU-170670|reactome:R-MMU-392170|reactome:R-MMU-400042|reactome:R-MMU-418594|reactome:R-MMU-9009391|interpro:IPR001408(G-protein alpha subunit, group I) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ZeBicuRGylbh8IORXPZnsDjSQWU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P60335 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-309059|ensembl:ENSMUSP00000054863 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O55135 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2000040|ensembl:ENSMUSP00000029142 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:if6_mouse(display_long)|uniprotkb:Eif6(gene name)|psi-mi:Eif6(display_short)|uniprotkb:Itgb4bp(gene name synonym)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034709.1|ensembl:ENSMUSG00000027613(gene)|ensembl:ENSMUST00000029142(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:VJmvvyZWezpZRVjVk9l76P0AYtY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P14873 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-764653|uniprotkb:E9QM11|ensembl:ENSMUSP00000068374 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:map1b_mouse(display_long)|uniprotkb:MAP1.2(gene name synonym)|uniprotkb:"MAP1(X)"(gene name synonym)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Mtap1b(gene name synonym)|uniprotkb:Mtap5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_032660.2|ensembl:ENSMUSG00000052727(gene)|ensembl:ENSMUST00000064762(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017085"(response to insecticide)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0016358"(dendrite development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P14873 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:8Ph5u01KvXbfedKGBXu5cGckp7Y10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q04447 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-1634233|uniprotkb:Q3KQP4|uniprotkb:Q3TKI3|uniprotkb:Q3U5P5|uniprotkb:Q3UF71|uniprotkb:Q9CXK6|ensembl:ENSMUSP00000001304 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:kcrb_mouse(display_long)|uniprotkb:Ckb(gene name)|psi-mi:Ckb(display_short)|uniprotkb:Ckbb(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:B-CK(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_067248.1|ensembl:ENSMUSG00000001270(gene)|ensembl:ENSMUST00000001304(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q04447|reactome:R-MMU-71288|reactome:R-MMU-9696264 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:7r2Owq3p9g124vCs/sG4m8aScuU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P57776 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284702|uniprotkb:Q68FG5|uniprotkb:Q9CWW2|uniprotkb:Q9CWY1|uniprotkb:Q9CYD4|uniprotkb:Q9CYJ5 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ef1d_mouse(display_long)|uniprotkb:Eef1d(gene name)|psi-mi:Eef1d(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_075729.2|refseq:NP_083939.1|interpro:IPR018940|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|refseq:NP_001272358.1|refseq:NP_001272359.1|refseq:NP_001272360.1|refseq:NP_001272361.1|refseq:NP_001272362.1|refseq:NP_001272363.1|mint:P57776|interpro:IPR036219|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0045202"(synapse)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|reactome:R-MMU-156842|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:u9Szyf5Sgd3WAlW/np+9e0VpsfA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O88974 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-79658|uniprotkb:Q6AXH8|uniprotkb:Q78N64|uniprotkb:Q78N65|uniprotkb:Q80U84|uniprotkb:Q8BTV6|uniprotkb:Q8CIX7|uniprotkb:Q922K1 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:setb1_mouse(display_long)|uniprotkb:Setdb1(gene name)|psi-mi:Setdb1(display_short)|uniprotkb:Eset(gene name synonym)|uniprotkb:Kiaa0067(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0060348"(bone development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR001214(SET)|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|reactome:R-MMU-3214841|interpro:IPR002999(Tudor)|interpro:IPR025796 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:wopdjnSA/Ng9vtDW1AdBfPicNdo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q62318 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-346909|uniprotkb:P70391|uniprotkb:Q8C283|uniprotkb:Q99PN4|ensembl:ENSMUSP00000005705 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:tif1b_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short)|uniprotkb:Krip1(gene name synonym)|uniprotkb:Tif1b(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:KRAB-A-interacting protein(gene name synonym)|uniprotkb:KRIP-1(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:Kap1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_035718.2|dip:DIP-31477N|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q62318|rcsb pdb:6O5K|reactome:R-MMU-212436|ensembl:ENSMUSG00000005566(gene)|ensembl:ENSMUST00000005705(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:DvGJxQNohVWs++QEAyrqe4ngcz810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q9R112 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286055|uniprotkb:Q91XA1|uniprotkb:Q9D891|uniprotkb:Q8BW20|ensembl:ENSMUSP00000005953|ensembl:ENSMUSP00000106133 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:sqor_mouse(display_long)|uniprotkb:Sqor(gene name)|psi-mi:Sqor(display_short)|uniprotkb:Sqrdl(gene name synonym)|uniprotkb:Sulfide quinone oxidoreductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001155975.1|refseq:NP_067482.4|ensembl:ENSMUSG00000005803(gene)|ensembl:ENSMUST00000005953(transcript)|ensembl:ENSMUST00000110506(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0048038"(quinone binding)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0070224"("sulfide:quinone oxidoreductase activity")|go:"GO:0070813"(hydrogen sulfide metabolic process)|go:"GO:0071949"(FAD binding)|interpro:IPR015904(Sulphide quinone-reductase)|interpro:IPR023753|interpro:IPR036188|mint:Q9R112|refseq:XP_006500029.1|reactome:R-MMU-1614517 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:RkVW764zkNYixWZfDLAxfDGHmk810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q7TMX2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-400426 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q7tmx2_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR021133|interpro:IPR031090|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0065003"(protein-containing complex assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:s8HJI5y072H/cMGIlvxJMhe8Yu010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P17182 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P67984 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286197|uniprotkb:P41104|ensembl:ENSMUSP00000099480|ensembl:ENSMUSP00000118787|ensembl:ENSMUSP00000140276 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl22_mouse(display_long)|uniprotkb:Rpl22(gene name)|psi-mi:Rpl22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033105.1|ensembl:ENSMUSG00000028936(gene)|ensembl:ENSMUST00000103191(transcript)|ensembl:ENSMUST00000139685(transcript)|ensembl:ENSMUST00000188151(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P67984|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0098793"(presynapse) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:8YjwLFx7406UlWyCGYWpxG8sbMY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6PB44 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284816|uniprotkb:Q69ZJ0|uniprotkb:Q8R1Z5|uniprotkb:Q923E6|ensembl:ENSMUSP00000039580 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:ptn23_mouse(display_long)|uniprotkb:Ptpn23(gene name)|psi-mi:Ptpn23(display_short)|uniprotkb:Kiaa1471(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001074512.1|ensembl:ENSMUSG00000036057(gene)|ensembl:ENSMUST00000040021(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:1903387"(positive regulation of homophilic cell adhesion)|go:"GO:1903393"(positive regulation of adherens junction organization)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004328(BRO1)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR025304|interpro:IPR029021|interpro:IPR038499|mint:Q6PB44|rcsb pdb:2W10|go:"GO:0032456"(endocytic recycling)|dip:DIP-48351N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:RMwyrq5YcR4mYY++zyj+oyLYSaU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q80T67 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286331 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q80t67_mouse(display_long)|uniprotkb:Zfp871(gene name)|psi-mi:Zfp871(display_short)|uniprotkb:mKIAA3006(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_766046.3|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:NGEmJlns0LavztBDZZqBZw5btLo10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q922S4 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-772547|uniprotkb:Q8K2U1|uniprotkb:Q3TCR8|uniprotkb:Q3TXZ6|ensembl:ENSMUSP00000131553 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pde2a_mouse(display_long)|uniprotkb:Cyclic GMP-stimulated phosphodiesterase(gene name synonym)|uniprotkb:Pde2a(gene name)|psi-mi:Pde2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001137321.1|refseq:XP_006507590.1|refseq:NP_001137320.1|ensembl:ENSMUSG00000110195(gene)|ensembl:ENSMUST00000163751(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003170"(heart valve development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0004118"(cGMP-stimulated cyclic-nucleotide phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010749"(regulation of nitric oxide mediated signal transduction)|go:"GO:0010752"(regulation of cGMP-mediated signaling)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030552"(cAMP binding)|go:"GO:0030553"(cGMP binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0035904"(aorta development)|go:"GO:0036004"(GAF domain binding)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0046069"(cGMP catabolic process)|go:"GO:0047555"(3',5'-cyclic-GMP phosphodiesterase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097457"(hippocampal mossy fiber)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003018(GAF)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR029016|interpro:IPR036971|mint:Q922S4|rcsb pdb:1MC0|reactome:R-MMU-418457|reactome:R-MMU-418555 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:Mb4AbU3k9lQ/qLUITe5AJ1NZdk810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8BX10 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-776241|uniprotkb:Q3UK19|uniprotkb:Q80VY8|uniprotkb:Q8BM78|uniprotkb:Q9CZU2|uniprotkb:B2RSM6|ensembl:ENSMUSP00000108124 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pgam5_mouse(display_long)|uniprotkb:Pgam5(gene name)|psi-mi:Pgam5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001157010.1|refseq:NP_082549.2|dip:DIP-32064N|ensembl:ENSMUSG00000029500(gene)|ensembl:ENSMUST00000112505(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q8BX10|reactome:R-MMU-8934903 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:m8AARXCf3lNoMo3JN7zcJNw5gwY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O08553 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q8VEB2 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4284907|uniprotkb:Q9D9N9|uniprotkb:Q9ER46|ensembl:ENSMUSP00000021467 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:sav1_mouse(display_long)|uniprotkb:Sav1(gene name)|psi-mi:Sav1(display_short)|uniprotkb:Ww45(gene name synonym)|uniprotkb:Wwp3(gene name synonym)|uniprotkb:45 kDa WW domain protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_071311.1|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|mint:Q8VEB2|rcsb pdb:2DWV|rcsb pdb:2YSB|rcsb pdb:7BQF|rcsb pdb:7BQG|reactome:R-MMU-2028269|go:"GO:0070699"(type II activin receptor binding)|ensembl:ENSMUSG00000021067(gene)|ensembl:ENSMUST00000021467(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:abXHo9/0Mg8QyYksGPhP+GxtPDY10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P84099 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2526813|uniprotkb:P14118|uniprotkb:P22908|ensembl:ENSMUSP00000017548 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rl19_mouse(display_long)|uniprotkb:Rpl19(gene name)|psi-mi:Rpl19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033104.2|ensembl:ENSMUSG00000017404(gene)|ensembl:ENSMUST00000017548(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84099|rcsb pdb:1K8D|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:O35295 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-647544|ensembl:ENSMUSP00000136957 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:purb_mouse(display_long)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)|uniprotkb:Vascular actin single-stranded DNA-binding factor 2 p44 component(gene name synonym)|uniprotkb:Purb(gene name)|psi-mi:Purb(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000094483(gene)|ensembl:ENSMUST00000179343(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|refseq:NP_035351.1|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|mint:O35295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:ZeoADmerELfkQ00oZ1w7a+wgQeA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:A2BI14 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4286033|ensembl:ENSMUSP00000116486 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:a2bi14_mouse(display_long)|uniprotkb:Ccdc171(gene name)|psi-mi:Ccdc171(display_short)|uniprotkb:4930473A06Rik(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000052407(gene)|ensembl:ENSMUST00000125077(transcript)|interpro:IPR038820 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:AoVNm0TOBNVnF4ZqoPkyu8r+6h410090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:E9Q557 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-688046|ensembl:ENSMUSP00000115062 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)" figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:A6ZI46 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285290|ensembl:ENSMUSP00000077687 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:a6zi46_mouse(display_long)|uniprotkb:Aldoart1(gene name)|psi-mi:Aldoart1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001186199.1|ensembl:ENSMUSG00000059343(gene)|ensembl:ENSMUST00000078617(transcript)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035686"(sperm fibrous sheath)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:vowUlBsqSGGYGSFc403QA9K59Go10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q3U410 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285154|uniprotkb:B1AS70|uniprotkb:Q3TZ30|ensembl:ENSMUSP00000095380 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:klh21_mouse(display_long)|uniprotkb:Klhl21(gene name)|psi-mi:Klhl21(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_001028524.1|ensembl:ENSMUSG00000073700(gene)|ensembl:ENSMUST00000097773(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005827"(polar microtubule)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035853"(chromosome passenger complex localization to spindle midzone)|go:"GO:0051301"(cell division)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030577|reactome:R-MMU-8951664|reactome:R-MMU-983168|go:"GO:0097602"(cullin family protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:5/v8hzs8W5QLjECjmG4Bj1KrcOM10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P62754 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-2000022|uniprotkb:P08227|uniprotkb:P10660|ensembl:ENSMUSP00000099878 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs6_mouse(display_long)|uniprotkb:Rps6(gene name)|psi-mi:Rps6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_033122.1|refseq:XP_011238179.1|ensembl:ENSMUSG00000028495(gene)|ensembl:ENSMUST00000102814(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR018282|mint:P62754|reactome:R-MMU-156827|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|dip:DIP-42772N|reactome:R-MMU-166208|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:beDuXCIqL99V9JlVfpzx7MdpH6810090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q99LL5 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285021|uniprotkb:Q9D6T6|ensembl:ENSMUSP00000001836 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:pwp1_mouse(display_long)|uniprotkb:Pwp1(gene name)|psi-mi:Pwp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_598754.2|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q99LL5|ensembl:ENSMUSG00000001785(gene)|ensembl:ENSMUST00000001836(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:+p9Zt4WaArKLsgVszp/FIYBjhUU10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:A1L333 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4285206 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:a1l333_mouse(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR012587(P68HR)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:bBYRf0irPQSVc5OJQXOx/PuiL0A10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:Q6ZWY3 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-3892454|uniprotkb:Q3UB68|ensembl:ENSMUSP00000046016 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:rs27l_mouse(display_long)|uniprotkb:Rps27l(gene name)|psi-mi:Rps27l(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4284701|imex:IM-16529-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 refseq:NP_080743.1|ensembl:ENSMUSG00000036781(gene)|ensembl:ENSMUST00000040917(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2020/10/21 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I10090 intact-crc:2FEDDD75913AF788|rigid:M/gTj4aGHMARcJhsc9Sszrj3GN8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P11499 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P11499 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9R049 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-3648125|uniprotkb:Q8K008|uniprotkb:Q99LH5 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:amfr_mouse(display_long)|uniprotkb:RING-type E3 ubiquitin transferase AMFR(gene name synonym)|uniprotkb:Amfr(gene name)|psi-mi:Amfr(display_short)|uniprotkb:Autocrine motility factor receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 mint:Q9R049|refseq:NP_035917.2|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0009987"(cellular process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|reactome:R-MMU-532668|interpro:IPR040675 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WllN35rkcf63zUF7TI4pQwTYfOI10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9R049 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-3648125|uniprotkb:Q8K008|uniprotkb:Q99LH5 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:amfr_mouse(display_long)|uniprotkb:RING-type E3 ubiquitin transferase AMFR(gene name synonym)|uniprotkb:Amfr(gene name)|psi-mi:Amfr(display_short)|uniprotkb:Autocrine motility factor receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 mint:Q9R049|refseq:NP_035917.2|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0009987"(cellular process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|reactome:R-MMU-532668|interpro:IPR040675 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WllN35rkcf63zUF7TI4pQwTYfOI10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q7TSH4 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P68372 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q78IK2 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2934077|ensembl:ENSMUSP00000093713|ensembl:ENSMUSP00000157712|ensembl:ENSMUSP00000158514|ensembl:ENSMUSP00000158561|uniprotkb:Q9ER48 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:atpmk_mouse(display_long)|uniprotkb:Atp5mk(gene name)|psi-mi:Atp5mk(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:Atp5md(gene name synonym)|uniprotkb:Dapit(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:Usmg5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000071528(gene)|ensembl:ENSMUST00000096014(transcript)|ensembl:ENSMUST00000235771(transcript)|ensembl:ENSMUST00000236170(transcript)|ensembl:ENSMUST00000237720(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|refseq:NP_075700.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:X/LBFKOsDisU3OvbILnMxEfWtNY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P68369 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P68368 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q03145 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-529701|uniprotkb:Q60633|uniprotkb:Q62212|uniprotkb:Q3UNI2|ensembl:ENSMUSP00000006614 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:epha2_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor MPK-5(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor SEK-2(gene name synonym)|uniprotkb:Epha2(gene name)|psi-mi:Epha2(display_short)|uniprotkb:Eck(gene name synonym)|uniprotkb:Sek2(gene name synonym)|uniprotkb:Myk2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034269.2|dip:DIP-829N|ensembl:ENSMUSG00000006445(gene)|ensembl:ENSMUST00000006614(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009986"(cell surface)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014028"(notochord formation)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019838"(growth factor binding)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0046849"(bone remodeling)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048320"(axial mesoderm formation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060035"(notochord cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0070160"(tight junction)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904238"(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|mint:Q03145|rcsb pdb:5ZRX|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:PppTcjFTGU5TuCWNmeqK9NVjb5w10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P20029 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P15116 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-397974|uniprotkb:Q64260|uniprotkb:Q6GU11|intact:EBI-2255565|ensembl:ENSMUSP00000025166 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cadh2_mouse(display_long)|uniprotkb:Cdh2(gene name)|psi-mi:Cdh2(display_short)|uniprotkb:Neural cadherin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_031690.3|ensembl:ENSMUSG00000024304(gene)|ensembl:ENSMUST00000025166(transcript)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030315"(T-tubule)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P15116|rcsb pdb:1NCG|rcsb pdb:1NCH|rcsb pdb:1NCI|rcsb pdb:1NCJ|rcsb pdb:1OP4|rcsb pdb:2QVI|rcsb pdb:3Q2W|rcsb pdb:4NUM|rcsb pdb:4NUP|rcsb pdb:4NUQ|reactome:R-MMU-381426|reactome:R-MMU-418990|reactome:R-MMU-525793|reactome:R-MMU-8957275|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|dip:DIP-31564N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Yon1udPwyvjKP2+GVGUcrsZtFng10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P97350 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4280963|uniprotkb:B2RSX3|ensembl:ENSMUSP00000027667|ensembl:ENSMUSP00000128418 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:pkp1_mouse(display_long)|uniprotkb:Pkp1(gene name)|psi-mi:Pkp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001300630.1|ensembl:ENSMUSG00000026413(gene)|ensembl:ENSMUST00000027667(transcript)|ensembl:ENSMUST00000163260(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030057"(desmosome)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:P97350|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_062619.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:0u1sErZ6PA3jKsFg7DQ9NlLMevI10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P68368 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9Z1N2 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-773812|uniprotkb:A2A8R3|ensembl:ENSMUSP00000099805 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:orc1_mouse(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:Orc1l(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035145.2|dip:DIP-32115N|ensembl:ENSMUSG00000028587(gene)|ensembl:ENSMUST00000102744(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4DOV|rcsb pdb:4DOW|reactome:R-MMU-176187|reactome:R-MMU-68616|reactome:R-MMU-68689|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:GY+oDJsPg1kc/AoUsBFnaLIBUO010090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q4ACU6 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q6P4S6 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2931619|uniprotkb:Q641L5|uniprotkb:Q66JZ5|uniprotkb:Q6ZQ09|uniprotkb:Q8K075|uniprotkb:Q9CYD5 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:sik3_mouse(display_long)|uniprotkb:Sik3(gene name)|psi-mi:Sik3(display_short)|uniprotkb:Kiaa0999(gene name synonym)|uniprotkb:Qsk(gene name synonym)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|refseq:NP_081774.3|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR034672 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:eIUTh+NVsTk8OSsys+A7gFfS9AM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BJ71 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2550206|ensembl:ENSMUSP00000078878|ensembl:ENSMUSP00000105174|ensembl:ENSMUSP00000148700|uniprotkb:Q3TED9|uniprotkb:Q8BIK7|uniprotkb:Q8K1R4|uniprotkb:Q8R592 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nup93_mouse(display_long)|uniprotkb:Nup93(gene name)|psi-mi:Nup93(display_short)|uniprotkb:Cip4(gene name synonym)|uniprotkb:Kiaa0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym)|uniprotkb:CBP-interacting protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000032939(gene)|ensembl:ENSMUST00000079961(transcript)|ensembl:ENSMUST00000109547(transcript)|ensembl:ENSMUST00000212824(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005813"(centrosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8BJ71|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-9615933|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|refseq:NP_765998.1|refseq:XP_006531437.1|refseq:XP_006531438.1|refseq:XP_006531439.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WvpVQMDhHGIOUStAtglTjVfqUc810090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P28663 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-775417|ensembl:ENSMUSP00000028926 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:snab_mouse(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein beta(gene name synonym)|uniprotkb:Brain protein I47(gene name synonym)|uniprotkb:Napb(gene name)|psi-mi:Napb(display_short)|uniprotkb:Snapb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_062606.1|ensembl:ENSMUSG00000027438(gene)|ensembl:ENSMUST00000028926(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:P28663|reactome:R-MMU-204005|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438|reactome:R-MMU-6811440 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:tKGtS2Dzj2CNItyIHAI2LOIiGyU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P99024 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BH59 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-445380|uniprotkb:A2BFG0|ensembl:ENSMUSP00000122103 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cmc1_mouse(display_long)|uniprotkb:Solute carrier family 25 member 12(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Slc25a12(gene name)|psi-mi:Slc25a12(display_short)|uniprotkb:Aralar1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_766024.1|ensembl:ENSMUSG00000027010(gene)|ensembl:ENSMUST00000151937(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q8BH59|reactome:R-MMU-70263|reactome:R-MMU-8963693 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:n5EwQVcmGB37DOgF1haZb8kCnqc10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P62748 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1634477|uniprotkb:P35333|ensembl:ENSMUSP00000071756 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hpcl1_mouse(display_long)|uniprotkb:Hpcal1(gene name)|psi-mi:Hpcal1(display_short)|uniprotkb:Visinin-like protein 3(gene name synonym)|uniprotkb:Neural visinin-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_057886.1|refseq:XP_006515219.1|refseq:XP_006515220.1|ensembl:ENSMUSG00000071379(gene)|ensembl:ENSMUST00000071858(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016020"(membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:ZLX+Km49SxhIW99F/wJ2adBYZ2Q10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q7TMM9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2255578|ensembl:ENSMUSP00000060246 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q62425 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9CQN1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4286155|uniprotkb:Q542I4|ensembl:ENSMUSP00000006137 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:trap1_mouse(display_long)|uniprotkb:Trap1(gene name)|psi-mi:Trap1(display_short)|uniprotkb:Hsp75(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080784.1|ensembl:ENSMUSG00000005981(gene)|ensembl:ENSMUST00000006137(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q9CQN1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:8DL4FdXZj8opXUye3mhVpcHjbdU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CG73 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9Z1N2 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-773812|uniprotkb:A2A8R3|ensembl:ENSMUSP00000099805 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:orc1_mouse(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:Orc1l(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035145.2|dip:DIP-32115N|ensembl:ENSMUSG00000028587(gene)|ensembl:ENSMUST00000102744(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4DOV|rcsb pdb:4DOW|reactome:R-MMU-176187|reactome:R-MMU-68616|reactome:R-MMU-68689|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:GY+oDJsPg1kc/AoUsBFnaLIBUO010090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CHI8 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2942504|uniprotkb:E9QKV1|uniprotkb:Q3TPY1|uniprotkb:Q5RKN8|uniprotkb:Q80TC8|uniprotkb:Q8BXI5|uniprotkb:Q8BYW3|uniprotkb:Q8C0P6|uniprotkb:Q8CHI7|uniprotkb:Q8VDF4|uniprotkb:Q9DA54 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ep400_mouse(display_long)|uniprotkb:Ep400(gene name)|psi-mi:Ep400(display_short)|uniprotkb:Kiaa1498(gene name synonym)|uniprotkb:Domino homolog(gene name synonym)|uniprotkb:p400 kDa SWI2/SNF2-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0070615"|go:"GO:1990405"(protein antigen binding)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR027417|interpro:IPR031575|interpro:IPR038718|reactome:R-MMU-2559584|reactome:R-MMU-2559586|refseq:NP_083613.2|refseq:NP_775089.1|refseq:XP_006535339.1|dip:DIP-61766N|mint:Q8CHI8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:vJHZG85phcSbMEgw8LlsZdF+52o10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P08553 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-445188|uniprotkb:A2VCT5|uniprotkb:Q0VDM8|uniprotkb:Q3HRJ6|uniprotkb:Q3TNS4|uniprotkb:Q3TPK2|uniprotkb:Q61961|uniprotkb:Q8BQ20 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nfm_mouse(display_long)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032717.2|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|interpro:IPR027697|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|mint:P08553 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:2HBUZIEhbbrfamAhbq7gyuRUaTk10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CFI7 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2549877|ensembl:ENSMUSP00000031167 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q62425 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P28663 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-775417|ensembl:ENSMUSP00000028926 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:snab_mouse(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein beta(gene name synonym)|uniprotkb:Brain protein I47(gene name synonym)|uniprotkb:Napb(gene name)|psi-mi:Napb(display_short)|uniprotkb:Snapb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_062606.1|ensembl:ENSMUSG00000027438(gene)|ensembl:ENSMUST00000028926(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:P28663|reactome:R-MMU-204005|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438|reactome:R-MMU-6811440 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:tKGtS2Dzj2CNItyIHAI2LOIiGyU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BJ71 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2550206|ensembl:ENSMUSP00000078878|ensembl:ENSMUSP00000105174|ensembl:ENSMUSP00000148700|uniprotkb:Q3TED9|uniprotkb:Q8BIK7|uniprotkb:Q8K1R4|uniprotkb:Q8R592 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nup93_mouse(display_long)|uniprotkb:Nup93(gene name)|psi-mi:Nup93(display_short)|uniprotkb:Cip4(gene name synonym)|uniprotkb:Kiaa0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym)|uniprotkb:CBP-interacting protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000032939(gene)|ensembl:ENSMUST00000079961(transcript)|ensembl:ENSMUST00000109547(transcript)|ensembl:ENSMUST00000212824(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005813"(centrosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8BJ71|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-9615933|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|refseq:NP_765998.1|refseq:XP_006531437.1|refseq:XP_006531438.1|refseq:XP_006531439.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WvpVQMDhHGIOUStAtglTjVfqUc810090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q569Z6 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2536252|ensembl:ENSMUSP00000079722 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tr150_mouse(display_long)|uniprotkb:Thrap3(gene name)|psi-mi:Thrap3(display_short)|uniprotkb:Trap150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000043962(gene)|ensembl:ENSMUST00000080919(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026667|interpro:IPR029199|go:"GO:0008380"(RNA splicing)|refseq:XP_011238805.1|refseq:NP_666265.3|refseq:XP_006503104.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Cb0vHuEX3Ew27z2gvfC/36tdeYE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P23927 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q571G4 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2553427|ensembl:ENSMUSP00000159391|ensembl:ENSMUSP00000159392|uniprotkb:Q8BMU8|uniprotkb:Q8C107|uniprotkb:Q3UYW5|uniprotkb:Q3KQN0|uniprotkb:A0JLY2 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:lin54_mouse(display_long)|uniprotkb:Kiaa2037(gene name synonym)|uniprotkb:Lin54(gene name)|psi-mi:Lin54(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000118665(gene)|ensembl:ENSMUST00000239512(transcript)|ensembl:ENSMUST00000239513(transcript)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0046872"(metal ion binding)|interpro:IPR005172(Tesmin/TSO1-like, CXC)|interpro:IPR028307|interpro:IPR033467|reactome:R-MMU-1538133|refseq:NP_001108482.1|refseq:NP_766302.2|refseq:XP_006534947.1|refseq:XP_006534949.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:e5Cmqo8YxFtVyqhBNYqYnWEIfyA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q3V2E0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281451 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q3v2e0_mouse(display_long)|uniprotkb:Try5(gene name)|psi-mi:Try5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR033116|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR043504 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:2D7DR7UChhapYkFYQMLQzHaxl2E10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q921U8 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4285038|uniprotkb:Q3TCV2|uniprotkb:Q6NSW1|uniprotkb:Q8CD93|uniprotkb:Q9JHG8|uniprotkb:Q9JLU7|uniprotkb:Q9R0D0|uniprotkb:Q9R253|uniprotkb:Q9Z0Q2|ensembl:ENSMUSP00000074621 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:smtn_mouse(display_long)|uniprotkb:Smtn(gene name)|psi-mi:Smtn(display_short)|uniprotkb:Smsmo(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001152756.1|refseq:NP_038898.2|refseq:NP_001271356.1|refseq:NP_001271357.1|refseq:NP_001271358.1|refseq:XP_017170075.1|ensembl:ENSMUSG00000020439(gene)|ensembl:ENSMUST00000075118(transcript)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:Q921U8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:buMeLGcMCw9xVDdWao7z+fXj9Bc10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:O35887 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-688160|ensembl:ENSMUSP00000031779 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:calu_mouse(display_long)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_031620.1|ensembl:ENSMUSG00000029767(gene)|ensembl:ENSMUST00000031779(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019899"(enzyme binding)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O35887|reactome:R-MMU-381426|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JSG2x2O/Lpg1JYjpePi+aqwSx+g10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9CPN9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281507|ensembl:ENSMUSP00000031931 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q9cpn9_mouse(display_long)|uniprotkb:2210010C04Rik(gene name)|psi-mi:2210010C04Rik(display_short)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000029882(gene)|ensembl:ENSMUST00000031931(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|refseq:NP_075822.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Zo4iGyJp1bpaflfoVpqcBqS6mm410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q7TMM9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2255578|ensembl:ENSMUSP00000060246 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P97313 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2272005|uniprotkb:E9QN15|uniprotkb:O88187|uniprotkb:P97928|uniprotkb:Q307W9|uniprotkb:Q3V2W8|uniprotkb:Q8C2A7|uniprotkb:Q9Z341|ensembl:ENSMUSP00000023352 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:prkdc_mouse(display_long)|uniprotkb:Prkdc(gene name)|psi-mi:Prkdc(display_short)|uniprotkb:Xrcc7(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035289.2|ensembl:ENSMUSG00000022672(gene)|ensembl:ENSMUST00000023352(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0002684"(positive regulation of immune system process)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1905221"(positive regulation of platelet formation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P97313|reactome:R-MMU-5693571|reactome:R-MMU-8866654 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:CE0UDetYkRmQdIxj+xDjU3hYpzo10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P97313 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2272005|uniprotkb:E9QN15|uniprotkb:O88187|uniprotkb:P97928|uniprotkb:Q307W9|uniprotkb:Q3V2W8|uniprotkb:Q8C2A7|uniprotkb:Q9Z341|ensembl:ENSMUSP00000023352 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:prkdc_mouse(display_long)|uniprotkb:Prkdc(gene name)|psi-mi:Prkdc(display_short)|uniprotkb:Xrcc7(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035289.2|ensembl:ENSMUSG00000022672(gene)|ensembl:ENSMUST00000023352(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0002684"(positive regulation of immune system process)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1905221"(positive regulation of platelet formation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P97313|reactome:R-MMU-5693571|reactome:R-MMU-8866654 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:CE0UDetYkRmQdIxj+xDjU3hYpzo10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P08113 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772439|uniprotkb:P11427|ensembl:ENSMUSP00000020238 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:enpl_mouse(display_long)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Grp94(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 99(gene name synonym)|uniprotkb:Polymorphic tumor rejection antigen 1(gene name synonym)|uniprotkb:Tumor rejection antigen gp96(gene name synonym)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Tra-1(gene name synonym)|uniprotkb:Tra1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035761.1|dip:DIP-32352N|ensembl:ENSMUSG00000020048(gene)|ensembl:ENSMUST00000020238(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071318"(cellular response to ATP)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08113|reactome:R-MMU-1679131|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-6785807|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:6hS1V+GSgQiDvTYBpzbfdL5FDcE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CG73 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P35700 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-444948|uniprotkb:Q3UBV4|uniprotkb:Q9CWI2|ensembl:ENSMUSP00000102078|ensembl:ENSMUSP00000114159 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:prdx1_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Osteoblast-specific factor 3(gene name synonym)|uniprotkb:Macrophage 23 kDa stress protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Msp23(gene name synonym)|uniprotkb:Paga(gene name synonym)|uniprotkb:Tdpx2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035164.1|ensembl:ENSMUST00000135573(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P35700|reactome:R-MMU-3299685|reactome:R-MMU-5628897|ensembl:ENSMUST00000106470(transcript)|ensembl:ENSMUSG00000028691(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:xOppWev1GtpILoJ1rY+tSPoymVU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P41133 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-309448|ensembl:ENSMUSP00000008016 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:id3_mouse(display_long)|uniprotkb:Id3(gene name)|psi-mi:Id3(display_short)|uniprotkb:Hlh462(gene name synonym)|uniprotkb:Id-3(gene name synonym)|uniprotkb:Idb3(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 462(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032347.1|ensembl:ENSMUSG00000007872(gene)|ensembl:ENSMUST00000008016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:wRsCFFWeh4NnuA3HwTmiVahLDtI10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BWT1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:15aWO97WJBNGYD449bAgjVjkgTY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q921U8 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4285038|uniprotkb:Q3TCV2|uniprotkb:Q6NSW1|uniprotkb:Q8CD93|uniprotkb:Q9JHG8|uniprotkb:Q9JLU7|uniprotkb:Q9R0D0|uniprotkb:Q9R253|uniprotkb:Q9Z0Q2|ensembl:ENSMUSP00000074621 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:smtn_mouse(display_long)|uniprotkb:Smtn(gene name)|psi-mi:Smtn(display_short)|uniprotkb:Smsmo(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001152756.1|refseq:NP_038898.2|refseq:NP_001271356.1|refseq:NP_001271357.1|refseq:NP_001271358.1|refseq:XP_017170075.1|ensembl:ENSMUSG00000020439(gene)|ensembl:ENSMUST00000075118(transcript)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:Q921U8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:buMeLGcMCw9xVDdWao7z+fXj9Bc10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9Z2X1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P07901 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9Z1R9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281463|ensembl:ENSMUSP00000031910 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q9z1r9_mouse(display_long)|uniprotkb:Prss1(gene name)|psi-mi:Prss1(display_short)|uniprotkb:Trygn16(gene name synonym)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000062751(gene)|ensembl:ENSMUST00000031910(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:Q9Z1R9|reactome:R-MMU-1462054|reactome:R-MMU-1592389|reactome:R-MMU-196741|reactome:R-MMU-6798695|reactome:R-MMU-6803157|refseq:NP_444473.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:kGcFBdHL3Chyo0DkqzQ8IOLUsHc10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P20029 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P35700 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-444948|uniprotkb:Q3UBV4|uniprotkb:Q9CWI2|ensembl:ENSMUSP00000102078|ensembl:ENSMUSP00000114159 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:prdx1_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Osteoblast-specific factor 3(gene name synonym)|uniprotkb:Macrophage 23 kDa stress protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Msp23(gene name synonym)|uniprotkb:Paga(gene name synonym)|uniprotkb:Tdpx2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035164.1|ensembl:ENSMUST00000135573(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P35700|reactome:R-MMU-3299685|reactome:R-MMU-5628897|ensembl:ENSMUST00000106470(transcript)|ensembl:ENSMUSG00000028691(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:xOppWev1GtpILoJ1rY+tSPoymVU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P68369 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P97318 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-81680|uniprotkb:A2A963|uniprotkb:A2A964|uniprotkb:A2A967|uniprotkb:A2A965|uniprotkb:A2A966|uniprotkb:A2A970|uniprotkb:P97316|uniprotkb:P97317|uniprotkb:Q9DAP9 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:dab1_mouse(display_long)|uniprotkb:Dab1(gene name)|psi-mi:Dab1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 reactome:R-MMU-8866376|go:"GO:0001764"(neuron migration)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0007494"(midgut development)|go:"GO:0021813"(cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0007628"(adult walking behavior)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0097477"(lateral motor column neuron migration)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1NTV|rcsb pdb:1NU2|rcsb pdb:1OQN|refseq:NP_034144.1|refseq:NP_796233.2|ensembl:ENSMUSG00000028519|ensembl:ENSMUSG00000028519|dip:DIP-30902N|refseq:XP_011238731.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Q9M7gpZkbDqd6D6pIKi66jrnDDo10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P97350 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4280963|uniprotkb:B2RSX3|ensembl:ENSMUSP00000027667|ensembl:ENSMUSP00000128418 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:pkp1_mouse(display_long)|uniprotkb:Pkp1(gene name)|psi-mi:Pkp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001300630.1|ensembl:ENSMUSG00000026413(gene)|ensembl:ENSMUST00000027667(transcript)|ensembl:ENSMUST00000163260(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030057"(desmosome)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:P97350|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_062619.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:0u1sErZ6PA3jKsFg7DQ9NlLMevI10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q7TSH4 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9Z2X1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P14602 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299023|ensembl:ENSMUSP00000005077 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q91YN9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9ERD7 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P62748 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1634477|uniprotkb:P35333|ensembl:ENSMUSP00000071756 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hpcl1_mouse(display_long)|uniprotkb:Hpcal1(gene name)|psi-mi:Hpcal1(display_short)|uniprotkb:Visinin-like protein 3(gene name synonym)|uniprotkb:Neural visinin-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_057886.1|refseq:XP_006515219.1|refseq:XP_006515220.1|ensembl:ENSMUSG00000071379(gene)|ensembl:ENSMUST00000071858(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016020"(membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:ZLX+Km49SxhIW99F/wJ2adBYZ2Q10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q6PDQ2 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P38647 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q03145 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-529701|uniprotkb:Q60633|uniprotkb:Q62212|uniprotkb:Q3UNI2|ensembl:ENSMUSP00000006614 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:epha2_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor MPK-5(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor SEK-2(gene name synonym)|uniprotkb:Epha2(gene name)|psi-mi:Epha2(display_short)|uniprotkb:Eck(gene name synonym)|uniprotkb:Sek2(gene name synonym)|uniprotkb:Myk2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034269.2|dip:DIP-829N|ensembl:ENSMUSG00000006445(gene)|ensembl:ENSMUST00000006614(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009986"(cell surface)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014028"(notochord formation)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019838"(growth factor binding)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0046849"(bone remodeling)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048320"(axial mesoderm formation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060035"(notochord cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0070160"(tight junction)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904238"(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|mint:Q03145|rcsb pdb:5ZRX|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:PppTcjFTGU5TuCWNmeqK9NVjb5w10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P17156 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-494667|intact:EBI-2942789|uniprotkb:Q99KD7|ensembl:ENSMUSP00000079306|ensembl:ENSMUSP00000151408 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hsp72_mouse(display_long)|uniprotkb:Hspa2(gene name)|psi-mi:Hspa2(display_short)|uniprotkb:Hcp70.2(gene name synonym)|uniprotkb:Hsp70-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001002012.1|refseq:NP_032327.2|refseq:XP_006515547.1|dip:DIP-42071N|ensembl:ENSMUSG00000059970(gene)|ensembl:ENSMUST00000080449(transcript)|ensembl:ENSMUST00000219555(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-MMU-3371568|go:"GO:0005739"(mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|go:"GO:0007286"(spermatid development)|interpro:IPR029048|interpro:IPR043129|reactome:R-MMU-3371453|reactome:R-MMU-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:wpWle7NX8ixNNq35mZt14enug4E10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q6PDQ2 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P15116 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-397974|uniprotkb:Q64260|uniprotkb:Q6GU11|intact:EBI-2255565|ensembl:ENSMUSP00000025166 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cadh2_mouse(display_long)|uniprotkb:Cdh2(gene name)|psi-mi:Cdh2(display_short)|uniprotkb:Neural cadherin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_031690.3|ensembl:ENSMUSG00000024304(gene)|ensembl:ENSMUST00000025166(transcript)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030315"(T-tubule)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P15116|rcsb pdb:1NCG|rcsb pdb:1NCH|rcsb pdb:1NCI|rcsb pdb:1NCJ|rcsb pdb:1OP4|rcsb pdb:2QVI|rcsb pdb:3Q2W|rcsb pdb:4NUM|rcsb pdb:4NUP|rcsb pdb:4NUQ|reactome:R-MMU-381426|reactome:R-MMU-418990|reactome:R-MMU-525793|reactome:R-MMU-8957275|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|dip:DIP-31564N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Yon1udPwyvjKP2+GVGUcrsZtFng10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q6KAP1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4284350 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q6kap1_mouse(display_long)|uniprotkb:mFLJ00246(gene name)|psi-mi:mFLJ00246(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:5QcSz2O7R6rCJRj9h/BqLDmYnFo10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9CY50 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772508|uniprotkb:Q3TIM3|uniprotkb:Q99MP2|ensembl:ENSMUSP00000021864 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ssra_mouse(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:Ssr1(gene name)|psi-mi:Ssr1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080241.3|ensembl:ENSMUSG00000021427(gene)|ensembl:ENSMUST00000021864(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit") psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ml+B+X8QgKftV7+u0eo1td8E9E010090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9CQN1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4286155|uniprotkb:Q542I4|ensembl:ENSMUSP00000006137 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:trap1_mouse(display_long)|uniprotkb:Trap1(gene name)|psi-mi:Trap1(display_short)|uniprotkb:Hsp75(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080784.1|ensembl:ENSMUSG00000005981(gene)|ensembl:ENSMUST00000006137(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q9CQN1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:8DL4FdXZj8opXUye3mhVpcHjbdU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9ET01 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2924798|uniprotkb:Q3UKJ0|ensembl:ENSMUSP00000071231 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:pygl_mouse(display_long)|uniprotkb:Pygl(gene name)|psi-mi:Pygl(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000021069(gene)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016208"(AMP binding)|go:"GO:0019842"(vitamin binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9ET01|reactome:R-MMU-6798695|reactome:R-MMU-70221|ensembl:ENSMUST00000071250(transcript)|refseq:NP_573461.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:2YFwG8X0rwpFN69mD6KWCFf/vpM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9QY53 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:O35887 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-688160|ensembl:ENSMUSP00000031779 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:calu_mouse(display_long)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_031620.1|ensembl:ENSMUSG00000029767(gene)|ensembl:ENSMUST00000031779(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019899"(enzyme binding)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O35887|reactome:R-MMU-381426|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JSG2x2O/Lpg1JYjpePi+aqwSx+g10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 intact:EBI-4283403 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 - psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:a2bfa6_mouse(display_short)|psi-mi:EBI-4283403(display_long)|uniprotkb:Naglu(gene name)|psi-mi:Naglu(display_short)|uniprotkb:RP23-440M18.1-001(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 uniprotkb:A2BFA6(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Wk3d0MOX4aDXePOotmzQPwoS8eQ10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q91YN9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9CPN9 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281507|ensembl:ENSMUSP00000031931 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q9cpn9_mouse(display_long)|uniprotkb:2210010C04Rik(gene name)|psi-mi:2210010C04Rik(display_short)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000029882(gene)|ensembl:ENSMUST00000031931(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|refseq:NP_075822.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Zo4iGyJp1bpaflfoVpqcBqS6mm410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CH18 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-645246|uniprotkb:Q6AXC9|uniprotkb:Q6PAR2|uniprotkb:Q80XE4|uniprotkb:Q8BJY0|uniprotkb:Q8BVN2|uniprotkb:Q8CGG1|uniprotkb:Q9CSR5|uniprotkb:Q05BR1|uniprotkb:Q05DK6|ensembl:ENSMUSP00000020268|ensembl:ENSMUSP00000151895 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ccar1_mouse(display_long)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Ccar1(gene name)|psi-mi:Ccar1(display_short)|uniprotkb:Carp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080477.1|refseq:XP_006514057.1|refseq:XP_006514058.1|refseq:XP_006514059.1|refseq:XP_006514060.1|refseq:XP_011241839.1|ensembl:ENSMUSG00000020074(gene)|ensembl:ENSMUST00000020268(transcript)|ensembl:ENSMUST00000219527(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8CH18|reactome:R-MMU-72163 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:fipMhp0uguP4AXVte036ScUyq5g10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P62991 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q792Z1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281491|ensembl:ENSMUSP00000071976 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q792z1_mouse(display_long)|uniprotkb:Try10(gene name)|psi-mi:Try10(display_short)|uniprotkb:Tcrb-V20(gene name synonym)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 reactome:R-MMU-6798695|reactome:R-MMU-6803157|reactome:R-MMU-196741|ensembl:ENSMUSG00000071521(gene)|ensembl:ENSMUST00000072103(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:Q792Z1|reactome:R-MMU-1462054|reactome:R-MMU-1592389|refseq:NP_001034085.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JNnSmjG/HeXjQUQKRxSfTj9PNkw10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CHI8 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2942504|uniprotkb:E9QKV1|uniprotkb:Q3TPY1|uniprotkb:Q5RKN8|uniprotkb:Q80TC8|uniprotkb:Q8BXI5|uniprotkb:Q8BYW3|uniprotkb:Q8C0P6|uniprotkb:Q8CHI7|uniprotkb:Q8VDF4|uniprotkb:Q9DA54 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ep400_mouse(display_long)|uniprotkb:Ep400(gene name)|psi-mi:Ep400(display_short)|uniprotkb:Kiaa1498(gene name synonym)|uniprotkb:Domino homolog(gene name synonym)|uniprotkb:p400 kDa SWI2/SNF2-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016607"(nuclear speck)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0070615"|go:"GO:1990405"(protein antigen binding)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR027417|interpro:IPR031575|interpro:IPR038718|reactome:R-MMU-2559584|reactome:R-MMU-2559586|refseq:NP_083613.2|refseq:NP_775089.1|refseq:XP_006535339.1|dip:DIP-61766N|mint:Q8CHI8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:vJHZG85phcSbMEgw8LlsZdF+52o10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P63038 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P23927 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9ET01 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2924798|uniprotkb:Q3UKJ0|ensembl:ENSMUSP00000071231 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:pygl_mouse(display_long)|uniprotkb:Pygl(gene name)|psi-mi:Pygl(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000021069(gene)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016208"(AMP binding)|go:"GO:0019842"(vitamin binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9ET01|reactome:R-MMU-6798695|reactome:R-MMU-70221|ensembl:ENSMUST00000071250(transcript)|refseq:NP_573461.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:2YFwG8X0rwpFN69mD6KWCFf/vpM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BH59 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-445380|uniprotkb:A2BFG0|ensembl:ENSMUSP00000122103 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:cmc1_mouse(display_long)|uniprotkb:Solute carrier family 25 member 12(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Slc25a12(gene name)|psi-mi:Slc25a12(display_short)|uniprotkb:Aralar1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_766024.1|ensembl:ENSMUSG00000027010(gene)|ensembl:ENSMUST00000151937(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q8BH59|reactome:R-MMU-70263|reactome:R-MMU-8963693 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:n5EwQVcmGB37DOgF1haZb8kCnqc10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CH18 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-645246|uniprotkb:Q6AXC9|uniprotkb:Q6PAR2|uniprotkb:Q80XE4|uniprotkb:Q8BJY0|uniprotkb:Q8BVN2|uniprotkb:Q8CGG1|uniprotkb:Q9CSR5|uniprotkb:Q05BR1|uniprotkb:Q05DK6|ensembl:ENSMUSP00000020268|ensembl:ENSMUSP00000151895 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ccar1_mouse(display_long)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Ccar1(gene name)|psi-mi:Ccar1(display_short)|uniprotkb:Carp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080477.1|refseq:XP_006514057.1|refseq:XP_006514058.1|refseq:XP_006514059.1|refseq:XP_006514060.1|refseq:XP_011241839.1|ensembl:ENSMUSG00000020074(gene)|ensembl:ENSMUST00000020268(transcript)|ensembl:ENSMUST00000219527(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8CH18|reactome:R-MMU-72163 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:fipMhp0uguP4AXVte036ScUyq5g10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q78IK2 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2934077|ensembl:ENSMUSP00000093713|ensembl:ENSMUSP00000157712|ensembl:ENSMUSP00000158514|ensembl:ENSMUSP00000158561|uniprotkb:Q9ER48 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:atpmk_mouse(display_long)|uniprotkb:Atp5mk(gene name)|psi-mi:Atp5mk(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:Atp5md(gene name synonym)|uniprotkb:Dapit(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:Usmg5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000071528(gene)|ensembl:ENSMUST00000096014(transcript)|ensembl:ENSMUST00000235771(transcript)|ensembl:ENSMUST00000236170(transcript)|ensembl:ENSMUST00000237720(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|refseq:NP_075700.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:X/LBFKOsDisU3OvbILnMxEfWtNY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q4ACU6 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q6KAP1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4284350 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q6kap1_mouse(display_long)|uniprotkb:mFLJ00246(gene name)|psi-mi:mFLJ00246(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:5QcSz2O7R6rCJRj9h/BqLDmYnFo10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P63017 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P62991 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P99024 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q02257 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P70670 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-647147|uniprotkb:E9QMB1|ensembl:ENSMUSP00000089680 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nacam_mouse(display_long)|uniprotkb:Gm1878(gene name synonym)|uniprotkb:Alpha-NAC, muscle-specific form(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001106670.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000092048(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:P70670 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:4QZh6JIwWgCTyZyvNxj5mmR6Bps10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P41133 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-309448|ensembl:ENSMUSP00000008016 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:id3_mouse(display_long)|uniprotkb:Id3(gene name)|psi-mi:Id3(display_short)|uniprotkb:Hlh462(gene name synonym)|uniprotkb:Id-3(gene name synonym)|uniprotkb:Idb3(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 462(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032347.1|ensembl:ENSMUSG00000007872(gene)|ensembl:ENSMUST00000008016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:wRsCFFWeh4NnuA3HwTmiVahLDtI10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q922F4 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2310445|ensembl:ENSMUSP00000001513 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb6_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080749.2|ensembl:ENSMUSG00000001473(gene)|ensembl:ENSMUST00000001513(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q922F4|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q792Z1 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281491|ensembl:ENSMUSP00000071976 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q792z1_mouse(display_long)|uniprotkb:Try10(gene name)|psi-mi:Try10(display_short)|uniprotkb:Tcrb-V20(gene name synonym)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 reactome:R-MMU-6798695|reactome:R-MMU-6803157|reactome:R-MMU-196741|ensembl:ENSMUSG00000071521(gene)|ensembl:ENSMUST00000072103(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:Q792Z1|reactome:R-MMU-1462054|reactome:R-MMU-1592389|refseq:NP_001034085.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JNnSmjG/HeXjQUQKRxSfTj9PNkw10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 intact:EBI-4283403 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 - psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:a2bfa6_mouse(display_short)|psi-mi:EBI-4283403(display_long)|uniprotkb:Naglu(gene name)|psi-mi:Naglu(display_short)|uniprotkb:RP23-440M18.1-001(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 uniprotkb:A2BFA6(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Wk3d0MOX4aDXePOotmzQPwoS8eQ10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P70670 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-647147|uniprotkb:E9QMB1|ensembl:ENSMUSP00000089680 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nacam_mouse(display_long)|uniprotkb:Gm1878(gene name synonym)|uniprotkb:Alpha-NAC, muscle-specific form(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001106670.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000092048(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:P70670 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:4QZh6JIwWgCTyZyvNxj5mmR6Bps10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BP92 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-642694|uniprotkb:O70341|uniprotkb:A2RT07|ensembl:ENSMUSP00000109915 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:rcn2_mouse(display_long)|uniprotkb:Taipoxin-associated calcium-binding protein 49(gene name synonym)|uniprotkb:Rcn2(gene name)|psi-mi:Rcn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_036122.2|ensembl:ENSMUSG00000032320(gene)|ensembl:ENSMUST00000114276(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8BP92|dip:DIP-46963N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:vsMMmWAPrlDNQDUxzH4wrp1Jub410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q61696 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299016|ensembl:ENSMUSP00000084586|uniprotkb:Q61697|uniprotkb:Q7TQD8|uniprotkb:Q9QWJ5 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hs71a_mouse(display_long)|uniprotkb:Hspa1a(gene name)|psi-mi:Hspa1a(display_short)|uniprotkb:Heat shock 70 kDa protein 3(gene name synonym)|uniprotkb:Hsp68(gene name synonym)|uniprotkb:Hsp70-3(gene name synonym)|uniprotkb:Hsp70A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000091971(gene)|ensembl:ENSMUST00000087328(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031249"(denatured protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042826"(histone deacetylase binding)|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045121"(membrane raft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q61696|reactome:R-MMU-3371453|reactome:R-MMU-450408|reactome:R-MMU-6798695|refseq:NP_034609.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:8ekBPoJrpT+Hr1LvZpflCkZEsss10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P08113 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772439|uniprotkb:P11427|ensembl:ENSMUSP00000020238 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:enpl_mouse(display_long)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Grp94(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 99(gene name synonym)|uniprotkb:Polymorphic tumor rejection antigen 1(gene name synonym)|uniprotkb:Tumor rejection antigen gp96(gene name synonym)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Tra-1(gene name synonym)|uniprotkb:Tra1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035761.1|dip:DIP-32352N|ensembl:ENSMUSG00000020048(gene)|ensembl:ENSMUST00000020238(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071318"(cellular response to ATP)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08113|reactome:R-MMU-1679131|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-6785807|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:6hS1V+GSgQiDvTYBpzbfdL5FDcE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P63038 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9CY50 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772508|uniprotkb:Q3TIM3|uniprotkb:Q99MP2|ensembl:ENSMUSP00000021864 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ssra_mouse(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:Ssr1(gene name)|psi-mi:Ssr1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080241.3|ensembl:ENSMUSG00000021427(gene)|ensembl:ENSMUST00000021864(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit") psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Ml+B+X8QgKftV7+u0eo1td8E9E010090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8CFI7 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2549877|ensembl:ENSMUSP00000031167 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q71LX8 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2657945 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P03995 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1634365|uniprotkb:Q80VX6|uniprotkb:Q925K2|uniprotkb:Q925K3|uniprotkb:A1E2H7|uniprotkb:A2AH87|uniprotkb:Q09J71|uniprotkb:Q3USS4|uniprotkb:Q496R4|uniprotkb:Q496S3|uniprotkb:Q7TQ30|ensembl:ENSMUSP00000064691|uniprotkb:B2RTI7 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:gfap_mouse(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001124492.1|refseq:NP_034407.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|ensembl:ENSMUSG00000020932(gene)|ensembl:ENSMUST00000067444(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|dip:DIP-1084N|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P03995 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:y7+aINs6vTxOHokkQCqgejlZfh010090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9QY53 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q3V2E0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281451 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q3v2e0_mouse(display_long)|uniprotkb:Try5(gene name)|psi-mi:Try5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR033116|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR043504 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:2D7DR7UChhapYkFYQMLQzHaxl2E10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q6P4S6 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2931619|uniprotkb:Q641L5|uniprotkb:Q66JZ5|uniprotkb:Q6ZQ09|uniprotkb:Q8K075|uniprotkb:Q9CYD5 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:sik3_mouse(display_long)|uniprotkb:Sik3(gene name)|psi-mi:Sik3(display_short)|uniprotkb:Kiaa0999(gene name synonym)|uniprotkb:Qsk(gene name synonym)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|refseq:NP_081774.3|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR034672 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:eIUTh+NVsTk8OSsys+A7gFfS9AM10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P59240 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q571G4 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2553427|ensembl:ENSMUSP00000159391|ensembl:ENSMUSP00000159392|uniprotkb:Q8BMU8|uniprotkb:Q8C107|uniprotkb:Q3UYW5|uniprotkb:Q3KQN0|uniprotkb:A0JLY2 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:lin54_mouse(display_long)|uniprotkb:Kiaa2037(gene name synonym)|uniprotkb:Lin54(gene name)|psi-mi:Lin54(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000118665(gene)|ensembl:ENSMUST00000239512(transcript)|ensembl:ENSMUST00000239513(transcript)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0046872"(metal ion binding)|interpro:IPR005172(Tesmin/TSO1-like, CXC)|interpro:IPR028307|interpro:IPR033467|reactome:R-MMU-1538133|refseq:NP_001108482.1|refseq:NP_766302.2|refseq:XP_006534947.1|refseq:XP_006534949.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:e5Cmqo8YxFtVyqhBNYqYnWEIfyA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P03995 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1634365|uniprotkb:Q80VX6|uniprotkb:Q925K2|uniprotkb:Q925K3|uniprotkb:A1E2H7|uniprotkb:A2AH87|uniprotkb:Q09J71|uniprotkb:Q3USS4|uniprotkb:Q496R4|uniprotkb:Q496S3|uniprotkb:Q7TQ30|ensembl:ENSMUSP00000064691|uniprotkb:B2RTI7 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:gfap_mouse(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_001124492.1|refseq:NP_034407.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|ensembl:ENSMUSG00000020932(gene)|ensembl:ENSMUST00000067444(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|dip:DIP-1084N|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P03995 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:y7+aINs6vTxOHokkQCqgejlZfh010090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P14602 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299023|ensembl:ENSMUSP00000005077 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P68372 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P70265 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-822637|uniprotkb:Q8VEI9 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:f262_mouse(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase heart-type isozyme(gene name synonym)|uniprotkb:Pfkfb2(gene name)|psi-mi:Pfkfb2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032851.2|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR027417|interpro:IPR029033|reactome:R-MMU-9634600|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033133"(positive regulation of glucokinase activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:J4kqEvmKe7qJlM9T8jVvqtHfyg410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P05213 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q922F4 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2310445|ensembl:ENSMUSP00000001513 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb6_mouse(display_long)|uniprotkb:Tubb6(gene name)|psi-mi:Tubb6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_080749.2|ensembl:ENSMUSG00000001473(gene)|ensembl:ENSMUST00000001513(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q922F4|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:HJaJs+zsyUZjmGSYEmEbcln56Z410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P70265 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-822637|uniprotkb:Q8VEI9 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:f262_mouse(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase heart-type isozyme(gene name synonym)|uniprotkb:Pfkfb2(gene name)|psi-mi:Pfkfb2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032851.2|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR027417|interpro:IPR029033|reactome:R-MMU-9634600|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033133"(positive regulation of glucokinase activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:J4kqEvmKe7qJlM9T8jVvqtHfyg410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P08553 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-445188|uniprotkb:A2VCT5|uniprotkb:Q0VDM8|uniprotkb:Q3HRJ6|uniprotkb:Q3TNS4|uniprotkb:Q3TPK2|uniprotkb:Q61961|uniprotkb:Q8BQ20 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nfm_mouse(display_long)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032717.2|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|interpro:IPR027697|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|mint:P08553 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:2HBUZIEhbbrfamAhbq7gyuRUaTk10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q71LX8 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2657945 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P97318 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-81680|uniprotkb:A2A963|uniprotkb:A2A964|uniprotkb:A2A967|uniprotkb:A2A965|uniprotkb:A2A966|uniprotkb:A2A970|uniprotkb:P97316|uniprotkb:P97317|uniprotkb:Q9DAP9 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:dab1_mouse(display_long)|uniprotkb:Dab1(gene name)|psi-mi:Dab1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 reactome:R-MMU-8866376|go:"GO:0001764"(neuron migration)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0007494"(midgut development)|go:"GO:0021813"(cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0007628"(adult walking behavior)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0097477"(lateral motor column neuron migration)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1NTV|rcsb pdb:1NU2|rcsb pdb:1OQN|refseq:NP_034144.1|refseq:NP_796233.2|ensembl:ENSMUSG00000028519|ensembl:ENSMUSG00000028519|dip:DIP-30902N|refseq:XP_011238731.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Q9M7gpZkbDqd6D6pIKi66jrnDDo10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P38647 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q02257 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9ERD7 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2255594|uniprotkb:Q3UF42|uniprotkb:Q5I036|ensembl:ENSMUSP00000071134 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb3_mouse(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_075768.1|dip:DIP-48419N|ensembl:ENSMUSG00000062380(gene)|ensembl:ENSMUST00000071134(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9ERD7|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q8BP92 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-642694|uniprotkb:O70341|uniprotkb:A2RT07|ensembl:ENSMUSP00000109915 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:rcn2_mouse(display_long)|uniprotkb:Taipoxin-associated calcium-binding protein 49(gene name synonym)|uniprotkb:Rcn2(gene name)|psi-mi:Rcn2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_036122.2|ensembl:ENSMUSG00000032320(gene)|ensembl:ENSMUST00000114276(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8BP92|dip:DIP-46963N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:vsMMmWAPrlDNQDUxzH4wrp1Jub410090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q569Z6 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2536252|ensembl:ENSMUSP00000079722 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tr150_mouse(display_long)|uniprotkb:Thrap3(gene name)|psi-mi:Thrap3(display_short)|uniprotkb:Trap150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000043962(gene)|ensembl:ENSMUST00000080919(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026667|interpro:IPR029199|go:"GO:0008380"(RNA splicing)|refseq:XP_011238805.1|refseq:NP_666265.3|refseq:XP_006503104.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:Cb0vHuEX3Ew27z2gvfC/36tdeYE10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P63017 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q61696 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-299016|ensembl:ENSMUSP00000084586|uniprotkb:Q61697|uniprotkb:Q7TQD8|uniprotkb:Q9QWJ5 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hs71a_mouse(display_long)|uniprotkb:Hspa1a(gene name)|psi-mi:Hspa1a(display_short)|uniprotkb:Heat shock 70 kDa protein 3(gene name synonym)|uniprotkb:Hsp68(gene name synonym)|uniprotkb:Hsp70-3(gene name synonym)|uniprotkb:Hsp70A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000091971(gene)|ensembl:ENSMUST00000087328(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031249"(denatured protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042826"(histone deacetylase binding)|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045121"(membrane raft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q61696|reactome:R-MMU-3371453|reactome:R-MMU-450408|reactome:R-MMU-6798695|refseq:NP_034609.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:8ekBPoJrpT+Hr1LvZpflCkZEsss10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:P05213 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287460|imex:IM-16529-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|caution:[EBI-2942789] The protein has been merged with EBI-494667 so the duplicated interactor has been deleted from this interaction.|caution:[EBI-4285676] The protein has been merged with EBI-1634016 so the duplicated interactor has been deleted from this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:46CA43B5E33CAFC7|rigid:QlhZ5587qm10xGi3siKKcG/pQ9M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59240 uniprotkb:Q9QY53 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4288147|imex:IM-16529-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) go:"GO:0005923"(bicellular tight junction) - - figure legend:Supp. Fig. 4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 intact-crc:B557DAE454B4179C|rigid:heFmindGP7uIxb8wQpfpsbQ10xA false - tandem tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q8K3E5 uniprotkb:Q71LX8 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-2657945 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P42932 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-772400|ensembl:ENSMUSP00000026704 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:tcpq_mouse(display_long)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Cct8(gene name)|psi-mi:Cct8(display_short)|uniprotkb:Cctq(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_033970.3|ensembl:ENSMUSG00000025613(gene)|ensembl:ENSMUST00000026704(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P42932|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:p3GMjguKvbAdbh4NkDyU8W4nr1E10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:O70433 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-299379|ensembl:ENSMUSP00000008280|ensembl:ENSMUSP00000141170|uniprotkb:P97448 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:fhl2_mouse(display_long)|uniprotkb:Fhl2(gene name)|psi-mi:Fhl2(display_short)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 ensembl:ENSMUSG00000008136(gene)|ensembl:ENSMUST00000008280(transcript)|ensembl:ENSMUST00000185893(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|refseq:NP_034342.1|refseq:XP_011236736.1|refseq:NP_001276462.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:F/ksOc8Ay71/DwSdKCK0mehHCCs10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:Q8CFW7 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-4280623|uniprotkb:Q8BP57|ensembl:ENSMUSP00000048320 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:c2d2a_mouse(display_long)|uniprotkb:Cc2d2a(gene name)|psi-mi:Cc2d2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_758478.1|ensembl:ENSMUSG00000039765(gene)|ensembl:ENSMUST00000048150(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0035082"(axoneme assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR028928|interpro:IPR035892|interpro:IPR041510|reactome:R-MMU-5620912 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:z0TKIWSf+GmLFh3rdbr6Pc56h3E10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:Q284W0 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-4280573 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:q284w0_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 interpro:IPR010796(B9)|refseq:NP_001034773.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P99024 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P38647 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:A2AM57 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-4280712|ensembl:ENSMUSP00000030029 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P07901 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P20029 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P63017 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P60710 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:Q02257 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:P05213 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K3E5 uniprotkb:Q8BZ64 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 intact:EBI-4280553|uniprotkb:Q3UMP0|uniprotkb:Q8BUE2|ensembl:ENSMUSP00000107367 psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:tect1_mouse(display_long)|uniprotkb:Tctn1(gene name)|psi-mi:Tctn1(display_short)|uniprotkb:Tect1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4280535|imex:IM-16529-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 refseq:NP_001034242.2|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0021523"(somatic motor neuron differentiation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021956"(central nervous system interneuron axonogenesis)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|ensembl:ENSMUSG00000038593(gene)|ensembl:ENSMUST00000111738(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001841"(neural tube formation)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR011677(Protein of unknown function DUF1619)|interpro:IPR040354|reactome:R-MMU-5620912|go:"GO:0060271"(cilium assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 rogid:ywnOXFDvdCoKPn9WRRK1hy8xu7o10090 intact-crc:244DD62FE1F0F4DF|rigid:DLnF9Ek/pkW0p8D+2OKHB9MbeKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:A5JUZ1 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280663 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q8R2Q6 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280946|uniprotkb:Q8CDF3|uniprotkb:Q9CRC5|ensembl:ENSMUSP00000025981 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:tect3_mouse(display_long)|uniprotkb:Tctn3(gene name)|psi-mi:Tctn3(display_short)|uniprotkb:Tect3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 ensembl:ENSMUSG00000025008(gene)|ensembl:ENSMUST00000025981(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060271"(cilium assembly)|interpro:IPR011677(Protein of unknown function DUF1619)|interpro:IPR040354|reactome:R-MMU-5620912|refseq:NP_080536.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:mwYqElOeiGsAbHwe3KqUyy9QYVo10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q2MV57 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4281008|uniprotkb:Q6PDZ5|uniprotkb:Q8C0B3|uniprotkb:Q9CXF5|ensembl:ENSMUSP00000159383 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:tect2_mouse(display_long)|uniprotkb:Tctn2(gene name)|psi-mi:Tctn2(display_short)|uniprotkb:Tect2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_080762.1|ensembl:ENSMUSG00000118662(gene)|ensembl:ENSMUST00000239501(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0060271"(cilium assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR011677(Protein of unknown function DUF1619)|interpro:IPR040354|reactome:R-MMU-5620912 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:jTw1eKE4d5C/2Jxeh/AG4kvg96E10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P97350 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280963|uniprotkb:B2RSX3|ensembl:ENSMUSP00000027667|ensembl:ENSMUSP00000128418 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:pkp1_mouse(display_long)|uniprotkb:Pkp1(gene name)|psi-mi:Pkp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_001300630.1|ensembl:ENSMUSG00000026413(gene)|ensembl:ENSMUST00000027667(transcript)|ensembl:ENSMUST00000163260(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030057"(desmosome)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:P97350|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_062619.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:0u1sErZ6PA3jKsFg7DQ9NlLMevI10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q02257 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P99024 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P05213 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P20029 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P60710 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q5NCM9 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280979|ensembl:ENSMUSP00000117524 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:q5ncm9_mouse(display_long)|uniprotkb:B9d1(gene name)|psi-mi:B9d1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 ensembl:ENSMUSG00000001039(gene)|ensembl:ENSMUST00000127889(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030030"(cell projection organization)|interpro:IPR010796(B9) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:nYe//H6Z3r6OY0ztBTolIttRygI10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q3TFF0 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280988 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:q3tff0_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|go:"GO:0005524"(ATP binding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0006457"(protein folding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:RZ+srevvpWpXwpx29WWzxPigMlc10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P38647 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P10126 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q8CFW7 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280623|uniprotkb:Q8BP57|ensembl:ENSMUSP00000048320 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:c2d2a_mouse(display_long)|uniprotkb:Cc2d2a(gene name)|psi-mi:Cc2d2a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_758478.1|ensembl:ENSMUSG00000039765(gene)|ensembl:ENSMUST00000048150(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0035082"(axoneme assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR028928|interpro:IPR035892|interpro:IPR041510|reactome:R-MMU-5620912 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:z0TKIWSf+GmLFh3rdbr6Pc56h3E10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P28301 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-642911|ensembl:ENSMUSP00000025409|ensembl:ENSMUSP00000129247 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:lyox_mouse(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:Ras excision protein(gene name synonym)|uniprotkb:Lox(gene name)|psi-mi:Lox(display_short)|uniprotkb:Rrg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_001273110.1|refseq:NP_001273111.1|refseq:NP_034858.2|ensembl:ENSMUSG00000024529(gene)|ensembl:ENSMUST00000025409(transcript)|ensembl:ENSMUST00000171470(transcript)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0035904"(aorta development)|go:"GO:0035905"(ascending aorta development)|go:"GO:0035906"(descending aorta development)|go:"GO:0042060"(wound healing)|go:"GO:0001568"(blood vessel development)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055001"(muscle cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061448"(connective tissue development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1900120"(regulation of receptor binding)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000586"(regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR001695(Lysyl oxidase)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005507"(copper ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0018158"(protein oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|interpro:IPR019828|mint:P28301|reactome:R-MMU-1566948|reactome:R-MMU-2243919 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:ehv+lVMTVIzWWWxaRlO+aIY53jk10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q8BZ64 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280553|uniprotkb:Q3UMP0|uniprotkb:Q8BUE2|ensembl:ENSMUSP00000107367 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:tect1_mouse(display_long)|uniprotkb:Tctn1(gene name)|psi-mi:Tctn1(display_short)|uniprotkb:Tect1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_001034242.2|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0021523"(somatic motor neuron differentiation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0021956"(central nervous system interneuron axonogenesis)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|ensembl:ENSMUSG00000038593(gene)|ensembl:ENSMUST00000111738(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001841"(neural tube formation)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR011677(Protein of unknown function DUF1619)|interpro:IPR040354|reactome:R-MMU-5620912|go:"GO:0060271"(cilium assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:ywnOXFDvdCoKPn9WRRK1hy8xu7o10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q9QZ83 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-1183650 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:P63017 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SW45 uniprotkb:Q71LX8 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-2657945 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281007|imex:IM-16529-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:28843C0035EB1E26|rigid:HR3cya+2bkJj+QBk1MFA7mXY4HI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P11499 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P59240 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P45376 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-299007|ensembl:ENSMUSP00000100045|uniprotkb:O70130|uniprotkb:Q99KC9 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:aldr_mouse(display_long)|uniprotkb:Akr1b1(gene name)|psi-mi:Akr1b1(display_short)|uniprotkb:Aldor1(gene name synonym)|uniprotkb:Aldr1(gene name synonym)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:Akr1b3(gene name synonym)|uniprotkb:Aldo-keto reductase family 1 member B3(gene name synonym)|uniprotkb:Aldose reductase(gene name synonym)|uniprotkb:Alr2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000001642(gene)|ensembl:ENSMUST00000102980(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005996"(monosaccharide metabolic process)|go:"GO:0006061"(sorbitol biosynthetic process)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010033"(response to organic substance)|go:"GO:0018505"(cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032838"(plasma membrane bounded cell projection cytoplasm)|go:"GO:0033010"(paranodal junction)|go:"GO:0035809"(regulation of urine volume)|go:"GO:0036130"(prostaglandin H2 endoperoxidase reductase activity)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042629"(mast cell granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043795"(glyceraldehyde oxidoreductase activity)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047956"(glycerol dehydrogenase [NADP+] activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:0097238"(cellular response to methylglyoxal)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:1901360"(organic cyclic compound metabolic process)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|mint:P45376|reactome:R-MMU-196108|reactome:R-MMU-5652227|refseq:NP_033788.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:h2dDmCsHxVwUhOeEhpxDrqGzXfc10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P62204 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P60710 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P48678 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-299212|ensembl:ENSMUSP00000029699|uniprotkb:P11516|uniprotkb:P97859|uniprotkb:Q3TIH0|uniprotkb:Q3TTS8|uniprotkb:Q3UCA0|uniprotkb:Q3UCJ8|uniprotkb:Q91WF2|uniprotkb:Q9DC21|uniprotkb:B3RH23|uniprotkb:B3RH24|uniprotkb:Q3U733|uniprotkb:Q3U7I5|uniprotkb:Q3UCU3 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:lmna_mouse(display_long)|uniprotkb:Lmna(gene name)|psi-mi:Lmna(display_short)|uniprotkb:Lmn1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|ensembl:ENSMUSG00000028063(gene)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|ensembl:ENSMUST00000029699(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P48678|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|rcsb pdb:1UFG|reactome:R-MMU-352238|reactome:R-MMU-4419969|refseq:NP_001002011.2|refseq:NP_001104572.1|refseq:NP_062263.1|refseq:XP_006501136.1|dip:DIP-31384N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:bJz9o/dZoD9E4CRP1FLYihybpwA10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P07356 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P63038 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q99LC4 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-2526893 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:q99lc4_mouse(display_long)|uniprotkb:Igh(gene name)|psi-mi:Igh(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) rcsb pdb:2NTF|rcsb pdb:2VIR|rcsb pdb:2VIS|rcsb pdb:1E6J|rcsb pdb:1JHK|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013106(Immunoglobulin V-set)|rcsb pdb:1F58|rcsb pdb:1JNL|rcsb pdb:1JNN|rcsb pdb:2A1W|rcsb pdb:2VIT|rcsb pdb:4Q0X|rcsb pdb:1AE6|rcsb pdb:1GIG|interpro:IPR036179|rcsb pdb:6C5H|rcsb pdb:6C5I|rcsb pdb:6C5J|rcsb pdb:6C5K psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:rb3tORVJa5CtHaOyY25mnAHnXQc10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P01027 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281083|uniprotkb:Q80XP1|ensembl:ENSMUSP00000024988|uniprotkb:Q61370 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:co3_mouse(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:HSE-MSF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000024164(gene)|ensembl:ENSMUST00000024988(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0008289"(lipid binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01027|rcsb pdb:6XZU|reactome:R-MMU-173736|reactome:R-MMU-174577|reactome:R-MMU-198933|reactome:R-MMU-375276|reactome:R-MMU-381426|reactome:R-MMU-418594|reactome:R-MMU-6798695|reactome:R-MMU-8957275|reactome:R-MMU-977606|refseq:NP_033908.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:VGFRYhKETrS9O7cyeJZyxBFgBL410090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P63017 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P20152 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q8VHX6 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P10126 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:A2AM57 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4280712|ensembl:ENSMUSP00000030029 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P05213 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q91YN9 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q6S385 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281194 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:q6s385_mouse(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) interpro:IPR036872|interpro:IPR035915|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR018159|refseq:NP_958795.2|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR030269|interpro:IPR001452(Src homology-3)|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:pQbtY/DLUR9KlmXVG0tpoB65mUo10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:A0JLV3 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281182 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:a0jlv3_mouse(display_long)|uniprotkb:Hist1h2bj(gene name)|psi-mi:Hist1h2bj(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000558(Histone H2B) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:rf5hopaVADdi6rY19wscFNqVvhI10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P07724 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-1183810|uniprotkb:Q3TV03|uniprotkb:Q61802|uniprotkb:Q8C7C7|uniprotkb:Q8C7H3|uniprotkb:Q8CG74|ensembl:ENSMUSP00000031314 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:albu_mouse(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short)|uniprotkb:Alb1(gene name synonym)|uniprotkb:Alb-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_033784.2|ensembl:ENSMUSG00000029368(gene)|ensembl:ENSMUST00000031314(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072341"(modified amino acid binding)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P07724|reactome:R-MMU-114608|reactome:R-MMU-159418|reactome:R-MMU-189451|reactome:R-MMU-189483|reactome:R-MMU-2168880|reactome:R-MMU-381426|reactome:R-MMU-879518|reactome:R-MMU-8957275|reactome:R-MMU-8964058|reactome:R-MMU-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:R7zO/mB332rAl8J+WrXfsHzjSYs10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P10107 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-647848|ensembl:ENSMUSP00000025561|ensembl:ENSMUSP00000158305 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:anxa1_mouse(display_long)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Anxa1(gene name)|psi-mi:Anxa1(display_short)|uniprotkb:Anx1(gene name synonym)|uniprotkb:Lpc1(gene name synonym)|uniprotkb:Lpc-1(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_034860.2|ensembl:ENSMUSG00000024659(gene)|ensembl:ENSMUST00000025561(transcript)|ensembl:ENSMUST00000235280(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P10107|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-444473|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044849"(estrous cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:V9sZHzXdA0iCeXidE8a0ahnWFoE10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P38647 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:A0AUV1 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281116 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:a0auv1_mouse(display_long)|uniprotkb:H2ac12(gene name)|psi-mi:H2ac12(display_short)|uniprotkb:Hist1h2ah(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) interpro:IPR032454|interpro:IPR032458|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR002119(Histone H2A) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:8f+treZLlPXAo+Sn4ZEEROZCBRY10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P58252 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-773856|uniprotkb:Q544E4|ensembl:ENSMUSP00000046101 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ef2_mouse(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_031933.1|ensembl:ENSMUSG00000034994(gene)|ensembl:ENSMUST00000047864(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P58252|reactome:R-MMU-156902|reactome:R-MMU-5358493|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:910/vo3IRjcncyPD4f43dPtS83o10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:A1L0U3 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281213 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:a1l0u3_mouse(display_long)|uniprotkb:Hist1h3e(gene name)|psi-mi:Hist1h3e(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:nAs7GtXsQsky1n7HdyFySRgwPog10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q9QZ83 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-1183650 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q8CG73 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P07091 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:A5JUZ1 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4280663 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P06151 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-444940|ensembl:ENSMUSP00000036386|ensembl:ENSMUSP00000103267 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ldha_mouse(display_long)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Ldha(gene name)|psi-mi:Ldha(display_short)|uniprotkb:Ldh-1(gene name synonym)|uniprotkb:Ldh1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_034829.1|ensembl:ENSMUSG00000063229(gene)|ensembl:ENSMUST00000005051(transcript)|ensembl:ENSMUST00000048209(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019661"(glucose catabolic process to lactate via pyruvate)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P06151|reactome:R-MMU-70268 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:IErFuOIWq53/XyIxWgUyVi76VnM10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P52480 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-647785|uniprotkb:Q3TBV8|uniprotkb:Q3TBW5|uniprotkb:Q3TC59|uniprotkb:Q3U1X3|uniprotkb:Q3U5P6|uniprotkb:Q4VC20|uniprotkb:Q64484|uniprotkb:Q91YI8|uniprotkb:Q9CWB1|ensembl:ENSMUSP00000034834 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:kpym_mouse(display_long)|uniprotkb:Pkm(gene name)|psi-mi:Pkm(display_short)|uniprotkb:Pk3(gene name synonym)|uniprotkb:Pkm2(gene name synonym)|uniprotkb:Pykm(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_035229.2|refseq:XP_006510918.1|refseq:NP_001240812.1|refseq:XP_011240975.1|dip:DIP-40536N|ensembl:ENSMUSG00000032294(gene)|ensembl:ENSMUST00000034834(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001889"(liver development)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043531"(ADP binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1902912"(pyruvate kinase complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P52480|reactome:R-MMU-6798695|reactome:R-MMU-70171 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:SWQx3aPATcnlExhyy8afjcrB+xo10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P20029 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:P99024 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QY53 uniprotkb:Q3UM23 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281076 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281129|imex:IM-16529-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:44D50BA068EEE5C1|rigid:vXf2JvZ1SjDXlIcu84ycYZUVd6s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9QZZ4 uniprotkb:O89019 intact:EBI-4281382|ensembl:ENSMUSP00000071777|uniprotkb:A2A637|uniprotkb:A2A638|uniprotkb:O70395|uniprotkb:Q5SX93|uniprotkb:Q7TMR5|uniprotkb:Q7TMR6|uniprotkb:Q9QWL6 intact:EBI-4281337|uniprotkb:O88849 psi-mi:myo15_mouse(display_long)|uniprotkb:Myo15a(gene name)|psi-mi:Myo15a(display_short)|uniprotkb:Myo15(gene name synonym)|uniprotkb:Unconventional myosin-15(gene name synonym) psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281305|imex:IM-16529-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000042678(gene)|ensembl:ENSMUST00000071880(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0098858"(actin-based cell projection)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR027417|interpro:IPR035487|interpro:IPR035963|interpro:IPR036028|interpro:IPR036057|interpro:IPR036961|interpro:IPR038185|interpro:IPR041795|mint:Q9QZZ4|rcsb pdb:6Y38|rcsb pdb:6Y9N|refseq:NP_001096641.1|refseq:NP_034992.2|refseq:NP_874357.2|refseq:XP_017169821.1|refseq:XP_017169822.1 interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:/SZaFfSAvP0AIlBs71OBrx+z59o10090 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 intact-crc:A20F5DD5626C71EB|rigid:UlIAytle2Vv9gOfFPCshMUxFLnc false - tandem tag:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:Q792Z1 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-4281491|ensembl:ENSMUSP00000071976 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:q792z1_mouse(display_long)|uniprotkb:Try10(gene name)|psi-mi:Try10(display_short)|uniprotkb:Tcrb-V20(gene name synonym)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 reactome:R-MMU-6798695|reactome:R-MMU-6803157|reactome:R-MMU-196741|ensembl:ENSMUSG00000071521(gene)|ensembl:ENSMUST00000072103(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:Q792Z1|reactome:R-MMU-1462054|reactome:R-MMU-1592389|refseq:NP_001034085.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:JNnSmjG/HeXjQUQKRxSfTj9PNkw10090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:Q7TT42 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-4281479 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:q7tt42_mouse(display_long)|uniprotkb:trypsinogen(gene name)|psi-mi:trypsinogen(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR033116|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR043504 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:Ocz4Dv4n8kxXUNL7mQ8/w+RZwHc10090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:P63017 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:Q3V2E0 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-4281451 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:q3v2e0_mouse(display_long)|uniprotkb:Try5(gene name)|psi-mi:Try5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR033116|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR043504 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:2D7DR7UChhapYkFYQMLQzHaxl2E10090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:A2AM57 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-4280712|ensembl:ENSMUSP00000030029 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:a2am57_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 ensembl:ENSMUSG00000028344(gene)|ensembl:ENSMUST00000030029(transcript)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_034699.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:fqKmADCnvWhHRBTQGHRRLITUafI10090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:Q8CGY8 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-928496|uniprotkb:A2ALY1|uniprotkb:Q6PG10|uniprotkb:Q8BXH6|uniprotkb:Q91Y38|ensembl:ENSMUSP00000045409 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:ogt1_mouse(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 refseq:XP_006527799.1|refseq:NP_631883.2|refseq:NP_001277464.1|refseq:XP_011245805.1|dip:DIP-35700N|ensembl:ENSMUSG00000034160(gene)|ensembl:ENSMUST00000044475(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003824"(catalytic activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:Q8CGY8|reactome:R-MMU-3214847|reactome:R-MMU-5675482|reactome:R-MMU-5689603 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:5N8o2WxL0V7gh1ZEa3l30GbrZa810090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TNH6 uniprotkb:Q9CPN9 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-4281507|ensembl:ENSMUSP00000031931 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:q9cpn9_mouse(display_long)|uniprotkb:2210010C04Rik(gene name)|psi-mi:2210010C04Rik(display_short)|uniprotkb:trypsinogen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281462|imex:IM-16529-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 ensembl:ENSMUSG00000029882(gene)|ensembl:ENSMUST00000031931(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|refseq:NP_075822.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:Zo4iGyJp1bpaflfoVpqcBqS6mm410090 intact-crc:6E271C2CE9DA4D66|rigid:ujvQaR9YPnR8ZrLZ7SxNFyAJfuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q8VDD5 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q8VHX6 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P60710 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:A1BN54 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-2308077|ensembl:ENSMUSP00000127176 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:a1bn54_mouse(display_long)|uniprotkb:Actn1(gene name)|psi-mi:Actn1(display_short)|uniprotkb:Actn1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_001333598.1|ensembl:ENSMUSG00000015143(gene)|ensembl:ENSMUST00000167327(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:ekpc3UwqtUNGaT7saZX0ukYcqsI10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q3UM23 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281076 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q3UH59 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281695|ensembl:ENSMUSP00000090661 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q3uh59_mouse(display_long)|uniprotkb:Myh10(gene name)|psi-mi:Myh10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000020900(gene)|ensembl:ENSMUST00000092984(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0016460"(myosin II complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|refseq:NP_780469.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:gODdELEKYILlc9W4X84k/RV05tU10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q99104 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-400199|uniprotkb:E9PUE5|ensembl:ENSMUSP00000116028 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:myo5a_mouse(display_long)|uniprotkb:Myo5a(gene name)|psi-mi:Myo5a(display_short)|uniprotkb:Dilute(gene name synonym)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_034994.2|ensembl:ENSMUSG00000034593(gene)|ensembl:ENSMUST00000123128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0001726"(ruffle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007601"(visual perception)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014046"(dopamine secretion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031982"(vesicle)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042476"(odontogenesis)|go:"GO:0042552"(myelination)|go:"GO:0042641"(actomyosin)|go:"GO:0042642"(actomyosin, myosin complex part)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099089"(establishment of endoplasmic reticulum localization to postsynapse)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099640"(axo-dendritic protein transport)|go:"GO:0150103"(reactive gliosis)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|go:"GO:0030318"(melanocyte differentiation)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR037988|mint:Q99104|rcsb pdb:2IX7|rcsb pdb:3WB8|rcsb pdb:4KP3|rcsb pdb:4ZLK|rcsb pdb:6KU0|reactome:R-MMU-2029482|interpro:IPR002710(Dilute)|go:"GO:0030141"(secretory granule)|dip:DIP-29542N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:8QtBlLL4DqB3An4CoCFVmvBEXBg10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q60598 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-397955|intact:EBI-4281621|uniprotkb:Q3UGC2|ensembl:ENSMUSP00000099368 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:src8_mouse(display_long)|uniprotkb:Cttn(gene name)|psi-mi:Cttn(display_short)|uniprotkb:Ems1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_031829.2|ensembl:ENSMUSG00000031078(gene)|ensembl:ENSMUST00000103079(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030054"(cell junction)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|interpro:IPR036028|mint:Q60598|rcsb pdb:2F9X|rcsb pdb:3ULR|rcsb pdb:5NV1|rcsb pdb:5NVJ|rcsb pdb:5NXJ|reactome:R-MMU-8856828|dip:DIP-31562N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:4hLyMrquWdlJnIX2pHuXqYtQgkE10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:A3KGU5 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281668|ensembl:ENSMUSP00000109346 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:a3kgu5_mouse(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000113717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|refseq:NP_001171139.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:yypmAHwRMgI24GzDP8yc1tbsaGs10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q61495 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-397946|uniprotkb:Q8CE03|ensembl:ENSMUSP00000076393|uniprotkb:A8WFQ4 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:dsg1a_mouse(display_long)|uniprotkb:Desmosomal glycoprotein I(gene name synonym)|uniprotkb:DG1(gene name synonym)|uniprotkb:DGI(gene name synonym)|uniprotkb:Dsg1a(gene name)|psi-mi:Dsg1a(display_short)|uniprotkb:Dsg1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_034209.2|ensembl:ENSMUSG00000069441(gene)|ensembl:ENSMUST00000077146(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696270 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:qT1MQ4BvfgVXy4wU4AwVIz3SueY10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P20029 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q3TRK3 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281753 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q3trk3_mouse(display_long)|uniprotkb:Dbn1(gene name)|psi-mi:Dbn1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR028438|go:"GO:0003779"(actin binding)|go:"GO:0007015"(actin filament organization)|refseq:NP_062787.2|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:cHPY5gyhKjIYCEjp1o1uKdX5d3U10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P68033 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-352284|uniprotkb:P04270|ensembl:ENSMUSP00000087736 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:actc_mouse(display_long)|uniprotkb:Actc1(gene name)|psi-mi:Actc1(display_short)|uniprotkb:Actc(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_033738.1|ensembl:ENSMUSG00000068614(gene)|ensembl:ENSMUST00000090269(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68033|reactome:R-MMU-390522|reactome:R-MMU-8980692|reactome:R-MMU-9013026 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P63017 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q80X90 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-688023|intact:EBI-777273|uniprotkb:E9QNV9|uniprotkb:Q8VHX4|uniprotkb:Q8VHX7|uniprotkb:Q99KY3|ensembl:ENSMUSP00000052020 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:flnb_mouse(display_long)|uniprotkb:Flnb(gene name)|psi-mi:Flnb(display_short)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_001074896.1|ensembl:ENSMUSG00000025278(gene)|ensembl:ENSMUST00000052678(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:Q80X90|reactome:R-MMU-1169408|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:A5bnyO/GwzIgn56NbxZGMkAWYk410090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q71LX8 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-2657945 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q02257 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P20152 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q9WTI7 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P13020 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-445180|uniprotkb:Q3UPB1|uniprotkb:Q8R590|intact:EBI-4281654|ensembl:ENSMUSP00000028239 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:gels_mouse(display_long)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Gsb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_666232.2|ensembl:ENSMUSG00000026879(gene)|ensembl:ENSMUST00000028239(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P13020|rcsb pdb:1NPH|rcsb pdb:4CBU|rcsb pdb:4CBW|rcsb pdb:4CBX|rcsb pdb:5MVV|rcsb pdb:6I4D|rcsb pdb:6I4E|rcsb pdb:6I4F|rcsb pdb:6I4G|rcsb pdb:6I4H|rcsb pdb:6I4I|rcsb pdb:6I4J|rcsb pdb:6I4K|rcsb pdb:6I4L|rcsb pdb:6I4M|reactome:R-MMU-264870|reactome:R-MMU-6798695|dip:DIP-31941N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:vByKB6qbsPzebkkufeXoP6n0SUI10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q6S385 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281194 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q6s385_mouse(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR036872|interpro:IPR035915|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR018159|refseq:NP_958795.2|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR030269|interpro:IPR001452(Src homology-3)|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:pQbtY/DLUR9KlmXVG0tpoB65mUo10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:A2APS1 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281603|ensembl:ENSMUSP00000028857 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q8CG73 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q62261 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P68372 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P07356 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q8BT15 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281612 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q8bt15_mouse(display_long)|uniprotkb:Lima1(gene name)|psi-mi:Lima1(display_short)|uniprotkb:D15Ertd366e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:OxT8m2UptFmBDy8qKlWDOvasnSg10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:A5JUZ1 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4280663 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P05213 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P97350 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4280963|uniprotkb:B2RSX3|ensembl:ENSMUSP00000027667|ensembl:ENSMUSP00000128418 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:pkp1_mouse(display_long)|uniprotkb:Pkp1(gene name)|psi-mi:Pkp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_001300630.1|ensembl:ENSMUSG00000026413(gene)|ensembl:ENSMUST00000027667(transcript)|ensembl:ENSMUST00000163260(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030057"(desmosome)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:P97350|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_062619.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:0u1sErZ6PA3jKsFg7DQ9NlLMevI10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P38647 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q9QZ83 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-1183650 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q05CR3 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-4281766 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q05cr3_mouse(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR036872|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR018159|interpro:IPR030269|interpro:IPR043197 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:Ow80ehFtfuBLsf9T2ee8uTh0lj010090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q3THE2 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-770040|uniprotkb:Q3TVH2|uniprotkb:Q9CQL8|ensembl:ENSMUSP00000042364|ensembl:ENSMUSP00000156763|ensembl:ENSMUSP00000156883 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:ml12b_mouse(display_long)|uniprotkb:Mrlc2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:Myl12b(gene name)|psi-mi:Myl12b(display_short)|uniprotkb:Mylc2b(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_075891.1|dip:DIP-31955N|ensembl:ENSMUSG00000034868(gene)|ensembl:ENSMUSG00000117098(gene)|ensembl:ENSMUST00000038446(transcript)|ensembl:ENSMUST00000233004(transcript)|ensembl:ENSMUST00000233357(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:Q3THE2|reactome:R-MMU-445355|reactome:R-MMU-5627123 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P10107 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-647848|ensembl:ENSMUSP00000025561|ensembl:ENSMUSP00000158305 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:anxa1_mouse(display_long)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Anxa1(gene name)|psi-mi:Anxa1(display_short)|uniprotkb:Anx1(gene name synonym)|uniprotkb:Lpc1(gene name synonym)|uniprotkb:Lpc-1(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_034860.2|ensembl:ENSMUSG00000024659(gene)|ensembl:ENSMUST00000025561(transcript)|ensembl:ENSMUST00000235280(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P10107|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-444473|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044849"(estrous cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:V9sZHzXdA0iCeXidE8a0ahnWFoE10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:Q9CV95 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-769056 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q9cv95_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 interpro:IPR028462|go:"GO:0030054"(cell junction)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR043197 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:F+IE/P/IuVEXd5Z2JRMz0u1nW4010090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75161 uniprotkb:P26443 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-773329|uniprotkb:Q8C273|ensembl:ENSMUSP00000022322 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:dhe3_mouse(display_long)|uniprotkb:Glud1(gene name)|psi-mi:Glud1(display_short)|uniprotkb:Glud(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4281653|imex:IM-16529-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:NP_032159.1|ensembl:ENSMUSG00000021794(gene)|ensembl:ENSMUST00000022322(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0007616"(long-term memory)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P26443|reactome:R-MMU-2151201|reactome:R-MMU-8964539 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:HbPeUm/tpMD6GrgM/863swTQqGA10090 intact-crc:2590EAD6E4E02FA9|rigid:UCP9gt+dTSPEBdfI7Aq4FX1qyXc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P11499 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6A078 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q80X90 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-688023|intact:EBI-777273|uniprotkb:E9QNV9|uniprotkb:Q8VHX4|uniprotkb:Q8VHX7|uniprotkb:Q99KY3|ensembl:ENSMUSP00000052020 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:flnb_mouse(display_long)|uniprotkb:Flnb(gene name)|psi-mi:Flnb(display_short)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001074896.1|ensembl:ENSMUSG00000025278(gene)|ensembl:ENSMUST00000052678(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:Q80X90|reactome:R-MMU-1169408|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:A5bnyO/GwzIgn56NbxZGMkAWYk410090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68369 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P60710 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9ERG2 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-911729|ensembl:ENSMUSP00000013130 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:strn3_mouse(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:Strn3(gene name)|psi-mi:Strn3(display_short)|uniprotkb:Gs2na(gene name synonym)|uniprotkb:Sg2na(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000020954(gene)|ensembl:ENSMUST00000013130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR001680(WD40 repeat)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERG2|refseq:NP_443205.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:TdtwkF77kxNiBo0jtPGVLwUlxoI10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P62204 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63017 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1J4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2552275|ensembl:ENSMUSP00000025649|uniprotkb:Q99LV3|uniprotkb:Q9QYK0|uniprotkb:Q3U8G3|uniprotkb:Q9WV39|uniprotkb:Q3UJC4|uniprotkb:Q3U4D0 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ddb1_mouse(display_long)|uniprotkb:Ddb1(gene name)|psi-mi:Ddb1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000024740(gene)|ensembl:ENSMUST00000025649(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_056550.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|mint:Q3U1J4|reactome:R-MMU-110314|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|go:"GO:0005654"(nucleoplasm)|dip:DIP-56812N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dvNwCrG9In1FV2j/+PrsSMvqFnk10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P38647 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8VDD5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q07113 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2891155|ensembl:ENSMUSP00000024599|uniprotkb:Q61822|uniprotkb:Q6LED1 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:mpri_mouse(display_long)|uniprotkb:Igf2r(gene name)|psi-mi:Igf2r(display_short)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:Q07113|reactome:R-MMU-432722|reactome:R-MMU-6798695|reactome:R-MMU-6811440|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUSG00000023830(gene)|ensembl:ENSMUST00000024599(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001889"(liver development)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|refseq:NP_034645.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:sqdDRrqMg68UCTjHNnqZACflsEs10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A2APS1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281603|ensembl:ENSMUSP00000028857 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a2aps1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000027378(gene)|ensembl:ENSMUST00000028857(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031514"(motile cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|refseq:NP_058598.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:isaz0raBAO1K1gl4XiL16lzt0JM10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A5JUZ1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4280663 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a5juz1_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short)|uniprotkb:EG216818(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q7TN13 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282197 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q7tn13_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036480|interpro:IPR036897|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR017926|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029062|interpro:IPR035686 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:gEKS8aEgMRHW9j5uSQJG0RQT9mE10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P68372 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2553564|uniprotkb:P05217|uniprotkb:Q3UJ73|uniprotkb:Q3TKF0|uniprotkb:Q99JZ6|ensembl:ENSMUSP00000042342 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tbb4b_mouse(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000036752(gene)|ensembl:ENSMUST00000043584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045298"(tubulin complex)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68372|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_666228.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q60692 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991777|uniprotkb:Q3V240|uniprotkb:Q60693|uniprotkb:Q8BJX9|uniprotkb:Q91VH5|ensembl:ENSMUSP00000018430|intact:EBI-4282155 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb6_mouse(display_long)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Psmb6(gene name)|psi-mi:Psmb6(display_short)|uniprotkb:Lmp19(gene name synonym)|uniprotkb:Low molecular mass protein 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-174178|reactome:R-MMU-5676590|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-5687128|ensembl:ENSMUSG00000018286(gene)|ensembl:ENSMUST00000018430(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:Q60692|rcsb pdb:3UNB|rcsb pdb:3UNE|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|go:"GO:0005839"(proteasome core complex)|reactome:R-MMU-174154|refseq:NP_032972.3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:z+HBCqJQpl+Rkyn8MS3YM0V1TeQ10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P70333 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282223|ensembl:ENSMUSP00000050838|ensembl:ENSMUSP00000074483|ensembl:ENSMUSP00000108827|ensembl:ENSMUSP00000108828|ensembl:ENSMUSP00000108829|uniprotkb:Q3THV9 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hnrh2_mouse(display_long)|uniprotkb:Hnrnph2(gene name)|psi-mi:Hnrnph2(display_short)|uniprotkb:Hnrph2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001300645.1|refseq:NP_001300646.1|uniprotkb:A2BDV8(uniprot-removed-ac)|ensembl:ENSMUST00000074950(transcript)|ensembl:ENSMUST00000113202(transcript)|ensembl:ENSMUST00000113203(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P70333|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUST00000059297(transcript)|ensembl:ENSMUSG00000045427(gene)|ensembl:ENSMUST00000050331(transcript)|refseq:NP_063921.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:BKLnU/p+g6hd6joRgjXU+BO5i7o10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A3KGU5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281668|ensembl:ENSMUSP00000109346 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a3kgu5_mouse(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000113717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|refseq:NP_001171139.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:yypmAHwRMgI24GzDP8yc1tbsaGs10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A1E2B8 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282145 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a1e2b8_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0005524"(ATP binding)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ZWP3SAChvtexmuiM2xOxCL9ud0U10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P29416 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282080|uniprotkb:Q91XG3|uniprotkb:Q64246|ensembl:ENSMUSP00000026262 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:hexa_mouse(display_long)|uniprotkb:Hexa(gene name)|psi-mi:Hexa(display_short)|uniprotkb:Beta-N-acetylhexosaminidase subunit alpha(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000025232(gene)|ensembl:ENSMUST00000026262(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0004563"(beta-N-acetylhexosaminidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0042552"(myelination)|go:"GO:0042582"(azurophil granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005829"(cytosol)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0102148"(N-acetyl-beta-D-galactosaminidase activity)|interpro:IPR015883(Glycoside hydrolase, family 20, catalytic core)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025705|interpro:IPR029018|interpro:IPR029019|reactome:R-MMU-1660662|reactome:R-MMU-2022857|reactome:R-MMU-2024101|reactome:R-MMU-2160916|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_034551.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ghvPBVvCw6TIIs8Wazfh5sG+U+o10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P14873 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-764653|uniprotkb:E9QM11|ensembl:ENSMUSP00000068374 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:map1b_mouse(display_long)|uniprotkb:MAP1.2(gene name synonym)|uniprotkb:"MAP1(X)"(gene name synonym)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Mtap1b(gene name synonym)|uniprotkb:Mtap5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032660.2|ensembl:ENSMUSG00000052727(gene)|ensembl:ENSMUST00000064762(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017085"(response to insecticide)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0016358"(dendrite development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P14873 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:8Ph5u01KvXbfedKGBXu5cGckp7Y10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3THB3 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282050 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3thb3_mouse(display_long)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short)|uniprotkb:Hnrpm(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR035979|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|refseq:NP_001103383.1|interpro:IPR024667|interpro:IPR024666|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034990 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:YXsfJpITwlmQ11vfx3I9f9Ysx2I10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UH59 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281695|ensembl:ENSMUSP00000090661 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3uh59_mouse(display_long)|uniprotkb:Myh10(gene name)|psi-mi:Myh10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000020900(gene)|ensembl:ENSMUST00000092984(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0016460"(myosin II complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|refseq:NP_780469.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:gODdELEKYILlc9W4X84k/RV05tU10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P28301 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-642911|ensembl:ENSMUSP00000025409|ensembl:ENSMUSP00000129247 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:lyox_mouse(display_long)|uniprotkb:Lysyl oxidase(gene name synonym)|uniprotkb:Ras excision protein(gene name synonym)|uniprotkb:Lox(gene name)|psi-mi:Lox(display_short)|uniprotkb:Rrg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001273110.1|refseq:NP_001273111.1|refseq:NP_034858.2|ensembl:ENSMUSG00000024529(gene)|ensembl:ENSMUST00000025409(transcript)|ensembl:ENSMUST00000171470(transcript)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0035904"(aorta development)|go:"GO:0035905"(ascending aorta development)|go:"GO:0035906"(descending aorta development)|go:"GO:0042060"(wound healing)|go:"GO:0001568"(blood vessel development)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055001"(muscle cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061448"(connective tissue development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1900120"(regulation of receptor binding)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000586"(regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR001695(Lysyl oxidase)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005507"(copper ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0018158"(protein oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|interpro:IPR019828|mint:P28301|reactome:R-MMU-1566948|reactome:R-MMU-2243919 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ehv+lVMTVIzWWWxaRlO+aIY53jk10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q62261 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O09061 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991712|uniprotkb:Q62038|uniprotkb:Q62039|ensembl:ENSMUSP00000014913 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb1_mouse(display_long)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)|uniprotkb:Psmb1(gene name)|psi-mi:Psmb1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000014769(gene)|ensembl:ENSMUST00000014913(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|mint:O09061|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-75815|refseq:NP_035315.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:CIHxzlrtwKh+f15z5Uf8Bv4yJ0o10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UDS4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282135 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3uds4_mouse(display_long)|uniprotkb:Sqor(gene name)|psi-mi:Sqor(display_short)|uniprotkb:Sqrdl(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036188|interpro:IPR015904(Sulphide quinone-reductase)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR023753 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:5VhPmoMguderCoPBqj+vYNc39yQ10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6P9L1 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282173 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6p9l1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR006680(Amidohydrolase 1)|interpro:IPR036897|interpro:IPR036914|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR032466|go:"GO:0005524"(ATP binding)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016812"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides")|go:"GO:0016874"(ligase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:hjrxaxAVU5nojAo6/iZZnfCbv0s10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O70435 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991671|ensembl:ENSMUSP00000125548 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa3_mouse(display_long)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:Proteasome subunit K(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Psma3(gene name)|psi-mi:Psma3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035314.3|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|interpro:IPR023332|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|interpro:IPR029055|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|interpro:IPR037555|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|ensembl:ENSMUSG00000060073(gene)|ensembl:ENSMUST00000160027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|refseq:XP_017170485.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:NgV6tyZ0v25UGZ5FkGZNNLMJVjQ10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P26443 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-773329|uniprotkb:Q8C273|ensembl:ENSMUSP00000022322 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:dhe3_mouse(display_long)|uniprotkb:Glud1(gene name)|psi-mi:Glud1(display_short)|uniprotkb:Glud(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_032159.1|ensembl:ENSMUSG00000021794(gene)|ensembl:ENSMUST00000022322(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0007616"(long-term memory)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P26443|reactome:R-MMU-2151201|reactome:R-MMU-8964539 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:HbPeUm/tpMD6GrgM/863swTQqGA10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:O55234 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991760|uniprotkb:Q9R1P2|uniprotkb:Q3UZI1|uniprotkb:Q91X53|uniprotkb:Q9CWR4|ensembl:ENSMUSP00000022803 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psb5_mouse(display_long)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Psmb5(gene name)|psi-mi:Psmb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000022193(gene)|ensembl:ENSMUST00000022803(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0005813"(centrosome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:O55234|rcsb pdb:3UNB|rcsb pdb:3UNE|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-195253|reactome:R-MMU-68949|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-69017|reactome:R-MMU-8948751|reactome:R-MMU-69481|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|refseq:NP_035316.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:fYhsgekPQbsqZwwxI3ORdi9Sn0k10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P63037 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q02257 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1751183|uniprotkb:Q8CGD3|intact:EBI-4280673|ensembl:ENSMUSP00000001592|ensembl:ENSMUSP00000103026 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:plak_mouse(display_long)|uniprotkb:Jup(gene name)|psi-mi:Jup(display_short)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_034723.1|refseq:XP_006532378.1|refseq:XP_006532379.1|ensembl:ENSMUSG00000001552(gene)|ensembl:ENSMUST00000001592(transcript)|ensembl:ENSMUST00000107403(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:Q02257|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:vGVqOkILXpeS3KOS5oPBztoWuts10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UM23 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281076 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3um23_mouse(display_long)|uniprotkb:Rnh1(gene name)|psi-mi:Rnh1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR032675|go:"GO:0005737"(cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR041302 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pAT++Yo+GBp9/dwjxVAXna4N5eY10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P99024 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3U1G4 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4282128 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3u1g4_mouse(display_long)|uniprotkb:Exoc1(gene name)|psi-mi:Exoc1(display_short)|uniprotkb:Sec3l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|interpro:IPR019160|interpro:IPR028258 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:K9P9YJ1MVDPgVMEvI6DXMm18qOI10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q6S385 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281194 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q6s385_mouse(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036872|interpro:IPR035915|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR018159|refseq:NP_958795.2|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR030269|interpro:IPR001452(Src homology-3)|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:pQbtY/DLUR9KlmXVG0tpoB65mUo10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q9QUM9 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-991694|uniprotkb:Q0VGS3|uniprotkb:Q3TT07|uniprotkb:Q3U6Y2|ensembl:ENSMUSP00000021412 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:psa6_mouse(display_long)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:Psma6(gene name)|psi-mi:Psma6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_036098.1|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:Q9QUM9|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|ensembl:ENSMUSG00000021024(gene)|ensembl:ENSMUST00000021412(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|reactome:R-MMU-69481|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-69601 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:VgUJoxRfxHDdUz0LNg/kcEY95a010090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q02819 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-1634689|uniprotkb:Q3TU42|uniprotkb:Q9CWA1|uniprotkb:Q9D8J4|uniprotkb:Q9DBL3|ensembl:ENSMUSP00000147383 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:nucb1_mouse(display_long)|uniprotkb:Nucb1(gene name)|psi-mi:Nucb1(display_short)|uniprotkb:Nuc(gene name synonym)|uniprotkb:Nucb(gene name synonym)|uniprotkb:CALNUC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001157134.1|refseq:NP_032775.1|refseq:XP_017177513.1|refseq:XP_006540759.1|ensembl:ENSMUSG00000030824(gene)|ensembl:ENSMUST00000211765(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02819|reactome:R-MMU-381426|reactome:R-MMU-8957275|go:"GO:0005794"(Golgi apparatus) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:/Iqiy8TmMklf3hIyYKPce37SBP010090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P20029 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8VHX6 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:A1BN54 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2308077|ensembl:ENSMUSP00000127176 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:a1bn54_mouse(display_long)|uniprotkb:Actn1(gene name)|psi-mi:Actn1(display_short)|uniprotkb:Actn1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_001333598.1|ensembl:ENSMUSG00000015143(gene)|ensembl:ENSMUST00000167327(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:ekpc3UwqtUNGaT7saZX0ukYcqsI10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8CG73 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:P57780 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-445071|ensembl:ENSMUSP00000066068 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q3UHQ5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-2550458 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:q3uhq5_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:Gcn1l1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043022"(ribosome binding)|refseq:NP_766307.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:1t/G1ybGLV/oHg/3GijS0N8AWjk10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BP00 uniprotkb:Q8VDD5 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4282064|imex:IM-16529-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090 intact-crc:61E9C3E845F0F0DB|rigid:cdlyLohpFdDirsVhr7jNRaARhzM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P63096 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O15078 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P11021 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q7Z5J8 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287175|uniprotkb:Q3ZCS6|uniprotkb:Q4G0M2|uniprotkb:Q6ZU02|ensembl:ENSP00000313513|ensembl:ENSP00000427882|ensembl:ENSP00000507233 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ankar_human(display_long)|uniprotkb:ANKAR(gene name)|psi-mi:ANKAR(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011508976.1|refseq:NP_653309.3|ensembl:ENSG00000151687(gene)|ensembl:ENST00000313581(transcript)|ensembl:ENST00000520309(transcript)|ensembl:ENST00000684021(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002110(Ankyrin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036770|interpro:IPR043379 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:vOlfeAGugaEjnsup1X4NKtBy2AY9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q6ZMR3 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287038|uniprotkb:D3DQY5|ensembl:ENSP00000280706|ensembl:ENSP00000379516 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ldh6a_human(display_long)|uniprotkb:LDHAL6A(gene name)|psi-mi:LDHAL6A(display_short)|uniprotkb:LDHL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001137543.1|refseq:NP_659409.2|ensembl:ENSG00000166800(gene)|ensembl:ENST00000280706(transcript)|ensembl:ENST00000396213(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|reactome:R-HSA-70268 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Z6uGDymaNdG8rK3AfyypBV+FO8w9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q00325 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 psi-mi:"MI:0469"(intact) - crc64:78714C85931B22D5 figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O95989 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-713708|uniprotkb:B2R8N4|ensembl:ENSP00000476119 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:nudt3_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 3(gene name synonym)|uniprotkb:NUDT3(gene name)|psi-mi:NUDT3(display_short)|uniprotkb:DIPP(gene name synonym)|uniprotkb:DIPP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000272325(gene)|ensembl:ENST00000607016(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000298"(endopolyphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008486"(diphosphoinositol-polyphosphate diphosphatase activity)|go:"GO:0015961"(diadenosine polyphosphate catabolic process)|go:"GO:0034431"("bis(5'-adenosyl)-hexaphosphatase activity")|go:"GO:0034432"("bis(5'-adenosyl)-pentaphosphatase activity")|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0052840"(inositol diphosphate tetrakisphosphate diphosphatase activity)|go:"GO:0052842"(inositol diphosphate pentakisphosphate diphosphatase activity)|go:"GO:0071543"(diphosphoinositol polyphosphate metabolic process)|go:"GO:0071544"(diphosphoinositol polyphosphate catabolic process)|go:"GO:0110154"(RNA decapping)|go:"GO:1901907"(diadenosine pentaphosphate catabolic process)|go:"GO:1901909"(diadenosine hexaphosphate catabolic process)|go:"GO:1901911"("adenosine 5'-(hexahydrogen pentaphosphate) catabolic process")|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|rcsb pdb:2FVV|rcsb pdb:6PCK|rcsb pdb:6PCL|rcsb pdb:6WO7|rcsb pdb:6WO8|rcsb pdb:6WO9|rcsb pdb:6WOA|rcsb pdb:6WOB|rcsb pdb:6WOC|rcsb pdb:6WOD|rcsb pdb:6WOE|rcsb pdb:6WOF|rcsb pdb:6WOG|rcsb pdb:6WOH|rcsb pdb:6WOI|rcsb pdb:2Q9P|reactome:R-HSA-1855167|refseq:NP_006694.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:3DKu6lLJM7uQ2EiUi3NzDPEcZ1g9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q16774 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2340074|uniprotkb:B1ANH1|ensembl:ENSP00000317659|ensembl:ENSP00000355677|ensembl:ENSP00000355679|ensembl:ENSP00000355687|ensembl:ENSP00000355691 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:kgua_human(display_long)|uniprotkb:GUK1(gene name)|psi-mi:GUK1(display_short)|uniprotkb:GMK(gene name synonym)|uniprotkb:GMP kinase(gene name synonym)|uniprotkb:GMPK(gene name synonym)|uniprotkb:Guanylate kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000849.1|refseq:NP_001152863.1|refseq:NP_001229768.1|refseq:NP_001152862.1|refseq:NP_001229769.1|ensembl:ENSG00000143774(gene)|ensembl:ENST00000312726(transcript)|ensembl:ENST00000366716(transcript)|ensembl:ENST00000366718(transcript)|ensembl:ENST00000366726(transcript)|ensembl:ENST00000366730(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006163"(purine nucleotide metabolic process)|go:"GO:0006185"(dGDP biosynthetic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0034436"(glycoprotein transport)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046054"(dGMP metabolic process)|go:"GO:0046060"(dATP metabolic process)|go:"GO:0046711"(GDP biosynthetic process)|go:"GO:0046939"(nucleotide phosphorylation)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR017665(Guanylate kinase, sub-group)|interpro:IPR020590|interpro:IPR027417|rcsb pdb:6NUI|reactome:R-HSA-2161541|reactome:R-HSA-499943 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:XJ4OokT2+8LY9P1bUKmFwmRXt249606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q8WVX9 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9NX20 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2560190|uniprotkb:Q9HB70|uniprotkb:Q9BYD0|ensembl:ENSP00000300151 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL16m(gene name synonym)|uniprotkb:PNAS-111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_060310.1|ensembl:ENSG00000166902(gene)|ensembl:ENST00000300151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|mint:Q9NX20|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P68371 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q06830 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O14735 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-358858|uniprotkb:Q6FGU1|uniprotkb:Q6ZN70|ensembl:ENSP00000219789|ensembl:ENSP00000454453|ensembl:ENSP00000457339|uniprotkb:B4DUV0|uniprotkb:H3BTV1 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:cdipt_human(display_long)|uniprotkb:CDIPT(gene name)|psi-mi:CDIPT(display_short)|uniprotkb:PIS(gene name synonym)|uniprotkb:PIS1(gene name synonym)|uniprotkb:Phosphatidylinositol synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001273514.1|refseq:NP_006310.1|ensembl:ENSG00000103502(gene)|ensembl:ENST00000219789(transcript)|ensembl:ENST00000569956(transcript)|ensembl:ENST00000570016(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043178"(alcohol binding)|go:"GO:0046341"(CDP-diacylglycerol metabolic process)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-HSA-1483226|dip:DIP-54492N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:SIs1nKd3UxZREA2Sxl4MxxBNYvM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P05023 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P78527 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9UK22 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287196|uniprotkb:B2R7K7|uniprotkb:Q5TGY0|uniprotkb:Q6FGJ7|uniprotkb:Q8TB29|uniprotkb:Q9UKC6|ensembl:ENSP00000346240 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:fbx2_human(display_long)|uniprotkb:FBXO2(gene name)|psi-mi:FBXO2(display_short)|uniprotkb:FBX2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_036300.2|ensembl:ENSG00000116661(gene)|ensembl:ENST00000354287(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0043197"(dendritic spine)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|mint:Q9UK22|reactome:R-HSA-8951664|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Ynr/gzgujCVKo9XgalXSfZdvm/Y9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P30086 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P55209 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P40925 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-709625|uniprotkb:B7Z3I7|uniprotkb:Q6I9V0|uniprotkb:B2R5V5|uniprotkb:B4DUN2|uniprotkb:F5H098|ensembl:ENSP00000233114|ensembl:ENSP00000446395 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:mdhc_human(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:MDH1(gene name)|psi-mi:MDH1(display_short)|uniprotkb:MDHA(gene name synonym)|uniprotkb:Diiodophenylpyruvate reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001186040.1|refseq:NP_001186041.1|refseq:NP_005908.1|refseq:NP_001303303.1|ensembl:ENSG00000014641(gene)|ensembl:ENST00000233114(transcript)|ensembl:ENST00000544381(transcript)|go:"GO:0004470"(malic enzyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0047860"(diiodophenylpyruvate reductase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010945(Malate dehydrogenase, NAD or NADP)|interpro:IPR011274(Malate dehydrogenase, NAD-dependent, cytosolic)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40925|reactome:R-HSA-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:SbY7B81CiCRe8tXpVpSdT1sKGOU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P31689 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q96A65 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P28300 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-3893481|uniprotkb:B2R5Q3|uniprotkb:Q5FWF0|ensembl:ENSP00000231004 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:lyox_human(display_long)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)|uniprotkb:Lysyl oxidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002308.2|dip:DIP-49007N|ensembl:ENSG00000113083(gene)|ensembl:ENST00000231004(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0035905"(ascending aorta development)|go:"GO:0035906"(descending aorta development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055001"(muscle cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061448"(connective tissue development)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1900120"(regulation of receptor binding)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000586"(regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR019828|mint:P28300|reactome:R-HSA-1566948|reactome:R-HSA-2243919|go:"GO:0046716"(muscle cell cellular homeostasis) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:bDUlKQ5akDOhya4GydJ+PaLs7Fo9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q5SRE5 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1049404|uniprotkb:Q14675|uniprotkb:Q2TA87|uniprotkb:Q7Z3K8|uniprotkb:Q8IWF1|intact:EBI-2555229|ensembl:ENSP00000361658 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:nu188_human(display_long)|uniprotkb:NUP188(gene name)|psi-mi:NUP188(display_short)|uniprotkb:KIAA0169(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_056169.1|ensembl:ENSG00000095319(gene)|ensembl:ENST00000372577(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018864|interpro:IPR044840|mint:Q5SRE5|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:eoj+tg9RAVKcVlT9ku1ozXCa3u89606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q7L5N7 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4280011|uniprotkb:A3KBM1|uniprotkb:Q6MZJ6|uniprotkb:Q9NX23|ensembl:ENSP00000262134 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pcat2_human(display_long)|uniprotkb:LPCAT2(gene name)|psi-mi:LPCAT2(display_short)|uniprotkb:AYTL1(gene name synonym)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:1-alkylglycerophosphocholine O-acetyltransferase(gene name synonym)|uniprotkb:"Acetyl-CoA:lyso-platelet-activating factor acetyltransferase"(gene name synonym)|uniprotkb:Acyltransferase-like 1(gene name synonym)|uniprotkb:1-alkenylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 11(gene name synonym)|uniprotkb:AGPAT11(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011521471.1|refseq:NP_060309.2|go:"GO:0047159"(1-alkenylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047192"(1-alkylglycerophosphocholine O-acetyltransferase activity)|go:"GO:0050200"(plasmalogen synthase activity)|go:"GO:0061024"(membrane organization)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-1482788|ensembl:ENSG00000087253(gene)|ensembl:ENST00000262134(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:7kcizNpGgOtfpMwKgx9kv6Hn7+s9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q8TEA8 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287111|uniprotkb:A8K5X5|uniprotkb:D3DW37|uniprotkb:Q496D1|uniprotkb:Q5W184|uniprotkb:Q8WXU8|uniprotkb:Q9BW67|uniprotkb:Q9H464|uniprotkb:Q9H474|ensembl:ENSP00000366672 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dtd1_human(display_long)|uniprotkb:DTD1(gene name)|psi-mi:DTD1(display_short)|uniprotkb:C20orf88(gene name synonym)|uniprotkb:HARS2(gene name synonym)|uniprotkb:Histidyl-tRNA synthase-related(gene name synonym)|uniprotkb:"Gly-tRNA(Ala) deacylase"(gene name synonym)|uniprotkb:DNA-unwinding element-binding protein B(gene name synonym)|uniprotkb:DUEB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_543010.3|refseq:NP_001304972.1|interpro:IPR023509|mint:Q8TEA8|rcsb pdb:2OKV|ensembl:ENSG00000125821(gene)|ensembl:ENST00000377452(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006399"(tRNA metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051500"("D-tyrosyl-tRNA(Tyr) deacylase activity")|interpro:IPR003732("D-tyrosyl-tRNA(Tyr) deacylase") psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:xv8w85tCe2A1hPgsPS6wG3peR7I9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q16658 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-351076|uniprotkb:Q96IH1|uniprotkb:A6NI89|uniprotkb:Q96IC5|uniprotkb:Q9BRF1|uniprotkb:B2RE97|ensembl:ENSP00000371798 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:fscn1_human(display_long)|uniprotkb:FSCN1(gene name)|psi-mi:FSCN1(display_short)|uniprotkb:FAN1(gene name synonym)|uniprotkb:HSN(gene name synonym)|uniprotkb:SNL(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym)|uniprotkb:55 kDa actin-bundling protein(gene name synonym)|uniprotkb:p55(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0044393"(microspike)|go:"GO:0045296"(cadherin binding)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q16658|rcsb pdb:1DFC|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|rcsb pdb:3LLP|refseq:NP_003079.1|ensembl:ENSG00000075618(gene)|ensembl:ENST00000382361(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|rcsb pdb:3P53|rcsb pdb:4GOV|rcsb pdb:4GOY|rcsb pdb:4GP3|rcsb pdb:6B0T|rcsb pdb:6I0Z|rcsb pdb:6I10|rcsb pdb:6I11|rcsb pdb:6I12|rcsb pdb:6I13|rcsb pdb:6I14|rcsb pdb:6I15|rcsb pdb:6I16|rcsb pdb:6I17|rcsb pdb:6I18|reactome:R-HSA-6785807|rcsb pdb:4GP0|dip:DIP-33171N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:yc9EJDCKGJGGEcEueR/yAY/fxRg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P01857 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q3ZCM7 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P57678 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q15121 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-714410|ensembl:ENSP00000353660|uniprotkb:O00511|uniprotkb:B1AKZ3 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pea15_human(display_long)|uniprotkb:Phosphoprotein enriched in diabetes(gene name synonym)|uniprotkb:PEA15(gene name)|psi-mi:PEA15(display_short)|uniprotkb:15 kDa phosphoprotein enriched in astrocytes(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000162734(gene)|ensembl:ENST00000360472(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0043278"(response to morphine)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR029546|mint:Q15121|rcsb pdb:4IZ5|rcsb pdb:4IZA|rcsb pdb:6P6B|rcsb pdb:6P6C|reactome:R-HSA-112409|reactome:R-HSA-5673001|refseq:XP_006711662.1|refseq:NP_001284505.1|refseq:NP_001284506.1|refseq:NP_001284507.1|refseq:NP_003759.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:jWuUfd7vJrrzsIlXVwY+GKwqB/k9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P02768 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P67809 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O43592 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q02413 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P25789 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P63241 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:A6NKN8 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4286989|uniprotkb:B2RV24|uniprotkb:B9EJG4|ensembl:ENSP00000426296 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pc4l1_human(display_long)|uniprotkb:PCP4L1(gene name)|psi-mi:PCP4L1(display_short)|uniprotkb:IQM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001096036.1|ensembl:ENSG00000248485(gene)|ensembl:ENST00000504449(transcript)|interpro:IPR033234 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/NdcyOsbAQXed7kj7fR7faCnzsA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P07900 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O14818 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P21333 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P25705 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q86YZ3 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P07996 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2530274|uniprotkb:A8K6H4|uniprotkb:B9EGH6|uniprotkb:Q15667|ensembl:ENSP00000260356|uniprotkb:B4E3J7|uniprotkb:Q59E99 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tsp1_human(display_long)|uniprotkb:THBS1(gene name)|psi-mi:THBS1(display_short)|uniprotkb:TSP(gene name synonym)|uniprotkb:TSP1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000137801(gene)|ensembl:ENST00000260356(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007155"(cell adhesion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032570"(response to progesterone)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0008201"(heparin binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033574"(response to testosterone)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383|mint:P07996|rcsb pdb:1LSL|rcsb pdb:1UX6|rcsb pdb:1Z78|rcsb pdb:1ZA4|rcsb pdb:2ERF|rcsb pdb:2ES3|rcsb pdb:2OUH|rcsb pdb:2OUJ|rcsb pdb:3R6B|rcsb pdb:5FOE|reactome:R-HSA-114608|reactome:R-HSA-186797|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-5083635|reactome:R-HSA-5173214|reactome:R-HSA-8936459|refseq:NP_003237.2|dip:DIP-1037N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:wqgWk4yWvhfEjrD+H6BdJrJgVgg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q6IBS0 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-722204|uniprotkb:Q9Y3F5|ensembl:ENSP00000303908 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:twf2_human(display_long)|uniprotkb:Twinfilin-1-like protein(gene name synonym)|uniprotkb:A6-related protein(gene name synonym)|uniprotkb:Protein tyrosine kinase 9-like(gene name synonym)|uniprotkb:TWF2(gene name)|psi-mi:TWF2(display_short)|uniprotkb:PTK9L(gene name synonym)|uniprotkb:MSTP011(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_009215.1|ensembl:ENSG00000247596(gene)|ensembl:ENST00000305533(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030016"(myofibril)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032420"(stereocilium)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|rcsb pdb:2VAC|rcsb pdb:2W0I|reactome:R-HSA-9662360|reactome:R-HSA-9662361 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:qWz7EmcCrpyHRA+wdEsiONY16zA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P12277 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P07197 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1105035|ensembl:ENSP00000221166|uniprotkb:Q4QRK6|uniprotkb:B4DGN2|uniprotkb:E9PBF7 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:nfm_human(display_long)|uniprotkb:NEFM(gene name)|psi-mi:NEFM(display_short)|uniprotkb:NEF3(gene name synonym)|uniprotkb:NFM(gene name synonym)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0097418"(neurofibrillary tangle)|interpro:IPR002957(Keratin, type I)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027697|interpro:IPR039008|ensembl:ENSG00000104722(gene)|ensembl:ENST00000221166(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0033693"(neurofilament bundle assembly)|refseq:NP_005373.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:dHWWqVqLrWoJXAH3BHzBeqyYJEE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O15083 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2684336|uniprotkb:Q2T9F6|uniprotkb:Q86TK4|intact:EBI-28970054|ensembl:ENSP00000288221|ensembl:ENSP00000417445 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:erc2_human(display_long)|uniprotkb:KIAA0378(gene name synonym)|uniprotkb:ERC2(gene name)|psi-mi:ERC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSP00000288221|ensembl:ENSP00000417445|refseq:NP_056391.1|ensembl:ENSG00000187672(gene)|ensembl:ENST00000288221(transcript)|ensembl:ENST00000460849(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030426"(growth cone)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR019323|interpro:IPR030625|refseq:XP_016861647.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Jn00b/1EcRz9ihgow+yYNXViD+w9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P50454 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9NV70 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P48539 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287270|uniprotkb:A6NDJ9|uniprotkb:Q93059|ensembl:ENSP00000329403|uniprotkb:Q6ICS4 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pcp4_human(display_long)|uniprotkb:PCP4(gene name)|psi-mi:PCP4(display_short)|uniprotkb:PEP19(gene name synonym)|uniprotkb:Brain-specific polypeptide PEP-19(gene name synonym)|uniprotkb:Purkinje cell protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006189.2|ensembl:ENSG00000183036(gene)|ensembl:ENST00000328619(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|interpro:IPR033236|rcsb pdb:2N77 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:ytDCHPPgQG6HIph9cxBSPC8+uaI9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P15924 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P04792 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N psi-mi:"MI:0469"(intact) - crc64:1B4DC44A6F6606D5 figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P60900 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q5D862 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2952722|ensembl:ENSP00000373370|uniprotkb:Q9H4U1 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:fila2_human(display_long)|uniprotkb:FLG2(gene name)|psi-mi:FLG2(display_short)|uniprotkb:IFPS(gene name synonym)|uniprotkb:Intermediate filament-associated and psoriasis-susceptibility protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSP00000373370|ensembl:ENSG00000143520(gene)|ensembl:ENST00000388718(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003303(Filaggrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|mint:Q5D862|reactome:R-HSA-6798695|go:"GO:0036457"(keratohyalin granule)|refseq:NP_001014364.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:b0VRX4uLQtUVeodRvtwEWgfmzZc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P13929 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9UKX5 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2568019|uniprotkb:Q8WYI8|uniprotkb:Q9UKQ1|ensembl:ENSP00000327290|uniprotkb:J3KQM2 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ita11_human(display_long)|uniprotkb:ITGA11(gene name)|psi-mi:ITGA11(display_short)|uniprotkb:MSTP018(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001004439.1|ensembl:ENSG00000137809(gene)|ensembl:ENST00000315757(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007517"(muscle organ development)|go:"GO:0008305"(integrin complex)|go:"GO:0016020"(membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0038064"(collagen receptor activity)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|reactome:R-HSA-216083 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:tFyxZTYEQ8Mo17+AUVUWFioPgFo9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9H0B8 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287061|uniprotkb:D3DUM0|uniprotkb:Q6P590|uniprotkb:Q6UWH0|uniprotkb:Q6UXC6|uniprotkb:Q96IB1|uniprotkb:Q96K61|ensembl:ENSP00000262424 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:crld2_human(display_long)|uniprotkb:CRISPLD2(gene name)|psi-mi:CRISPLD2(display_short)|uniprotkb:CRISP11(gene name synonym)|uniprotkb:LCRISP2(gene name synonym)|uniprotkb:Cysteine-rich secretory protein 11(gene name synonym)|uniprotkb:LCCL domain-containing cysteine-rich secretory protein 2(gene name synonym)|uniprotkb:UNQ2914/PRO1156/PRO9783(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_113664.1|go:"GO:0030133"(transport vesicle)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001283(Allergen V5/Tpx-1 related)|interpro:IPR004043(LCCL)|interpro:IPR014044(SCP-like extracellular)|interpro:IPR018244|interpro:IPR035940|interpro:IPR036609|reactome:R-HSA-6798695|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000103196(gene)|ensembl:ENST00000262424(transcript)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:XP_005256247.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:R49Nf8V+KJr79lhrO2wn9as8HW49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q13509 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O94760 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2859658|intact:EBI-4286999|uniprotkb:Q5HYC8|uniprotkb:Q86XK5|ensembl:ENSP00000284031 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ddah1_human(display_long)|uniprotkb:DDAH1(gene name)|psi-mi:DDAH1(display_short)|uniprotkb:DDAH(gene name synonym)|uniprotkb:DDAHI(gene name synonym)|uniprotkb:Dimethylargininase-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_036269.1|refseq:NP_001127917.1|refseq:XP_005270767.1|dip:DIP-61582N|ensembl:ENSG00000153904(gene)|ensembl:ENST00000284031(transcript)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|rcsb pdb:2JAJ|rcsb pdb:3I2E|rcsb pdb:3I4A|rcsb pdb:3P8E|rcsb pdb:3P8P|rcsb pdb:6DGE|rcsb pdb:6SZP|rcsb pdb:6SZQ|reactome:R-HSA-203615|go:"GO:0005829"(cytosol)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016403"(dimethylargininase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|interpro:IPR033197|interpro:IPR033199|go:"GO:0003824"(catalytic activity)|rcsb pdb:2JAI psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:5h5LJE27Q8aAH2WUE1bMfUgZBvQ9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P40939 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9H853 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-355902|ensembl:ENSP00000487719 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tba4b_human(display_long)|uniprotkb:TUBA4B(gene name)|psi-mi:TUBA4B(display_short)|uniprotkb:TUBA4(gene name synonym)|uniprotkb:Alpha-tubulin 4B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000243910(gene)|ensembl:ENST00000490341(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR036525|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:iBjadHjxXIhrRYnUm5yviGSvRhA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P11142 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P09417 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1220237|uniprotkb:Q53F52|uniprotkb:Q9H3M5|uniprotkb:B3KW71|uniprotkb:A8K158|ensembl:ENSP00000281243 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dhpr_human(display_long)|uniprotkb:QDPR(gene name)|psi-mi:QDPR(display_short)|uniprotkb:DHPR(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 33C member 1(gene name synonym)|uniprotkb:SDR33C1(gene name synonym)|uniprotkb:HDHPR(gene name synonym)|uniprotkb:Quinoid dihydropteridine reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000311.2|refseq:NP_001293069.1|ensembl:ENSG00000151552(gene)|ensembl:ENST00000281243(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004155"(6,7-dihydropteridine reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0010288"(response to lead ion)|go:"GO:0033762"(response to glucagon)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051066"(dihydrobiopterin metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:0070404"(NADH binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1HDR|reactome:R-HSA-8964208 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:RqJtqqhZKq5A8usbPddeDp3440c9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P13929 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P28066 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P04075 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9BUF5 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9H3K6 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1642537|uniprotkb:A1L454|uniprotkb:A7YDY3|ensembl:ENSP00000331127|ensembl:ENSP00000498355 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:bola2_human(display_long)|uniprotkb:BOLA2(gene name)|psi-mi:BOLA2(display_short)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2A(gene name synonym)|uniprotkb:My016(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:NP_001307508.1|refseq:XP_016855107.1|ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000330978(transcript)|ensembl:ENST00000651894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9H3K6|reactome:R-HSA-8950505 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:5TcFdmQcwx5trexmXkWp9Arn5zE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P01602 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2371313|uniprotkb:A0A075B6S8|intact:EBI-4286966|uniprotkb:P01596|uniprotkb:P01598|uniprotkb:P01604|ensembl:ENSP00000420436|ensembl:ENSP00000488639 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:kv105_human(display_long)|uniprotkb:IGKV1-5(gene name)|psi-mi:IGKV1-5(display_short)|uniprotkb:Ig kappa chain V-I region HK102(gene name synonym)|uniprotkb:Ig kappa chain V-I region CAR(gene name synonym)|uniprotkb:Ig kappa chain V-I region EU(gene name synonym)|uniprotkb:Ig kappa chain V-I region Kue(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000243466(gene)|ensembl:ENSG00000282801(gene)|ensembl:ENST00000496168(transcript)|ensembl:ENST00000632205(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:WKovn0mvryvDbJqn6iNbiFvN+rw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P61764 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-960169|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|uniprotkb:B1AM97|uniprotkb:Q68CM6|ensembl:ENSP00000362396 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:stxb1_human(display_long)|uniprotkb:STXBP1(gene name)|psi-mi:STXBP1(display_short)|uniprotkb:UNC18A(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:MUNC18-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001027392.1|refseq:NP_003156.1|ensembl:ENSG00000136854(gene)|ensembl:ENST00000373299(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0005739"(mitochondrion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61764|rcsb pdb:6L03|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-6794361|reactome:R-HSA-888590 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:yUYi89hDkfMdQ1BdH52swZQFCLk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9UJC5 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1171099|uniprotkb:Q9BPY5|uniprotkb:A8MQU2|uniprotkb:Q2VPC2|uniprotkb:Q5VV96|uniprotkb:Q6NSK8|uniprotkb:Q6P9E8|uniprotkb:Q7Z734|uniprotkb:Q8IWD3|ensembl:ENSP00000358853 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:sh3l2_human(display_long)|uniprotkb:SH3BGRL2(gene name)|psi-mi:SH3BGRL2(display_short)|uniprotkb:FASH3(gene name synonym)|uniprotkb:Fovea-associated SH3 domain-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_113657.1|ensembl:ENSG00000198478(gene)|ensembl:ENST00000369838(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031965"(nuclear membrane)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|rcsb pdb:2CT6|refseq:XP_016866833.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:lCYjqL/j1o+rDCdHKSOZHNXTcsU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9UHC6 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-310892|uniprotkb:Q14DG2|uniprotkb:Q52LV1|uniprotkb:Q5H9Q7|uniprotkb:Q9UQ12|uniprotkb:D3DWG2|ensembl:ENSP00000354778 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:cntp2_human(display_long)|uniprotkb:CNTNAP2(gene name)|psi-mi:CNTNAP2(display_short)|uniprotkb:CASPR2(gene name synonym)|uniprotkb:KIAA0868(gene name synonym)|uniprotkb:Cell recognition molecule Caspr2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_054860.1|ensembl:ENSG00000174469(gene)|ensembl:ENST00000361727(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008038"(neuron recognition)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019899"(enzyme binding)|go:"GO:0021756"(striatum development)|go:"GO:0021761"(limbic system development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0030673"(axolemma)|go:"GO:0031175"(neuron projection development)|go:"GO:0033010"(paranodal junction)|go:"GO:0035176"(social behavior)|go:"GO:0042297"(vocal learning)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045163"(clustering of voltage-gated potassium channels)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0071625"(vocalization behavior)|go:"GO:1903598"(positive regulation of gap junction assembly)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR029831|interpro:IPR036056|rcsb pdb:5Y4M|go:"GO:0044224"(juxtaparanode region of axon) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:lxU5rHVgSUp+Mf/i+BQYKZZqn+Q9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P55084 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O14810 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2691813|uniprotkb:B2R4R5|uniprotkb:A6NI80|uniprotkb:D3DVN3|uniprotkb:F1T0G1|ensembl:ENSP00000305613 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:cplx1_human(display_long)|uniprotkb:Complexin I(gene name synonym)|uniprotkb:Synaphin-2(gene name synonym)|uniprotkb:CPLX1(gene name)|psi-mi:CPLX1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006642.1|ensembl:ENSG00000168993(gene)|ensembl:ENST00000304062(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030073"(insulin secretion)|go:"GO:0030425"(dendrite)|go:"GO:0031201"(SNARE complex)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0044305"(calyx of Held)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070554"(synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR008849(Synaphin)|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-888590|dip:DIP-56109N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:fLmOGVm1+wD17+eGvRa7ZRErvMk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O00159 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P17066 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q8N434 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287157|ensembl:ENSP00000405482|ensembl:ENSP00000501457 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:svopl_human(display_long)|uniprotkb:SVOPL(gene name)|psi-mi:SVOPL(display_short)|uniprotkb:SV2-related protein-like(gene name synonym)|uniprotkb:SVOP-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011514099.1|refseq:NP_001132928.1|refseq:NP_777619.1|ensembl:ENSG00000157703(gene)|ensembl:ENST00000419765(transcript)|ensembl:ENST00000674285(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR005828(General substrate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|refseq:XP_005250200.1|refseq:XP_016867236.1|refseq:XP_016867237.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Vbjr8tGpvcURFenSl5istn0X6AU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q16555 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P00924 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-6468|uniprotkb:D6VV34|uniprotkb:P99013|ensemblfungi:YGR254W psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:eno1_yeast(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENOA(gene name synonym)|uniprotkb:HSP48(gene name synonym)|uniprotkb:YGR254W(locus name)|uniprotkb:G9160(orf name)|uniprotkb:2-phosphoglycerate dehydratase 1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 sgd:S000003486|reactome:R-SCE-70263|refseq:NP_011770.3|dip:DIP-5561N|reactome:R-SCE-70171|ensemblfungi:YGR254W(gene)|ensemblfungi:YGR254W_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:1904408"(melatonin binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:1EBG|rcsb pdb:1EBH|rcsb pdb:1ELS|rcsb pdb:1L8P|rcsb pdb:1NEL|rcsb pdb:1ONE|rcsb pdb:1P43|rcsb pdb:1P48|rcsb pdb:2AL1|rcsb pdb:2AL2|rcsb pdb:2ONE|rcsb pdb:2XGZ|rcsb pdb:2XH0|rcsb pdb:2XH2|rcsb pdb:2XH4|rcsb pdb:2XH7|rcsb pdb:3ENL|rcsb pdb:4ENL|rcsb pdb:5ENL|rcsb pdb:6ENL|rcsb pdb:7ENL psi-mi:"MI:0469"(intact) - crc64:69F45214DBD375BE figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:RuwK8M4LiafLorKJOh+lH88nPZE559292 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q14315 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O14893 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-443648|ensembl:ENSP00000250379|ensembl:ENSP00000308533|ensembl:ENSP00000379548|ensembl:ENSP00000416827|uniprotkb:Q2M3B3|uniprotkb:Q9H4F5|uniprotkb:Q9NS77|uniprotkb:Q9NS78|uniprotkb:Q9NS79|uniprotkb:B2R9W8 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gemi2_human(display_long)|uniprotkb:GEMIN2(gene name)|psi-mi:GEMIN2(display_short)|uniprotkb:SIP1(gene name synonym)|uniprotkb:Component of gems 2(gene name synonym)|uniprotkb:Survival of motor neuron protein-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000092208(gene)|ensembl:ENST00000250379(transcript)|ensembl:ENST00000308317(transcript)|ensembl:ENST00000396249(transcript)|ensembl:ENST00000412033(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR017364(Survival of motor neuron protein interacting, gemin2)|interpro:IPR035426|mint:O14893|rcsb pdb:2LEH|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|refseq:NP_001009182.1|refseq:NP_001009183.1|refseq:NP_003607.1|dip:DIP-32605N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:cCbpiHhHdfq+SNoIud5xipHgYVA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9BW71 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P68104 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q13322 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-80275|uniprotkb:O00427|uniprotkb:O00701|uniprotkb:O75222|uniprotkb:Q92606|uniprotkb:Q92907|uniprotkb:Q92948|intact:EBI-1760363|ensembl:ENSP00000381793|ensembl:ENSP00000385770|intact:EBI-1965437|uniprotkb:A7VJ95|uniprotkb:A4D258|uniprotkb:A8K0E6|uniprotkb:D3DVM9 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:grb10_human(display_long)|uniprotkb:GRB10(gene name)|psi-mi:GRB10(display_short)|uniprotkb:GRBIR(gene name synonym)|uniprotkb:KIAA0207(gene name synonym)|uniprotkb:GRB10 adapter protein(gene name synonym)|uniprotkb:Insulin receptor-binding protein Grb-IR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904738"(vascular associated smooth muscle cell migration)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035036|interpro:IPR035037|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q13322|rcsb pdb:1NRV|rcsb pdb:3HK0|reactome:R-HSA-1433557|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8853659|reactome:R-HSA-9607240|reactome:R-HSA-9648895|ensembl:ENSG00000106070(gene)|ensembl:ENST00000398812(transcript)|ensembl:ENST00000401949(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010467"(gene expression)|refseq:XP_011513606.1|refseq:XP_011513614.1|refseq:XP_011513618.1|refseq:NP_001001549.1|refseq:NP_001001550.1|refseq:NP_001001555.1|refseq:NP_005302.3|refseq:XP_016867534.1|refseq:XP_016867535.1|refseq:XP_016867552.1|refseq:XP_016867553.1|refseq:XP_016867554.1|refseq:XP_016867555.1|refseq:XP_016867556.1|refseq:XP_016867557.1|dip:DIP-31657N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:WBLkjS4iCC2gMTzR3izSFXGrBnk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P25787 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P04406 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9P2E9 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2371806|uniprotkb:A2A2S6|uniprotkb:A6NCN6|uniprotkb:O75300|uniprotkb:O75301|uniprotkb:Q5W165|uniprotkb:Q96SB2|uniprotkb:Q9BWP1|uniprotkb:Q9H476|uniprotkb:A0A0A0MRV0|intact:EBI-28985482|ensembl:ENSP00000246043|ensembl:ENSP00000367044 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rrbp1_human(display_long)|uniprotkb:RRBP1(gene name)|psi-mi:RRBP1(display_short)|uniprotkb:KIAA1398(gene name synonym)|uniprotkb:Ribosome receptor protein(gene name synonym)|uniprotkb:180 kDa ribosome receptor homolog(gene name synonym)|uniprotkb:ES/130-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001036041.1|refseq:NP_004578.2|ensembl:ENSP00000246043|ensembl:ENST00000360807|ensembl:ENSP00000354045|ensembl:ENST00000377807|ensembl:ENSP00000367038|ensembl:ENSP00000367044|ensembl:ENSG00000125844(gene)|ensembl:ENST00000246043(transcript)|ensembl:ENST00000377813(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR040248|mint:Q9P2E9 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:uOiVzIAM5bsSl2s1BSIfnUtZ3Ms9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P68363 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P50395 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P63098 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-915984|uniprotkb:B5MDU4|uniprotkb:P06705|uniprotkb:P15117|uniprotkb:Q08044|uniprotkb:Q53SL0|uniprotkb:B2RC10|ensembl:ENSP00000234310 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:canb1_human(display_long)|uniprotkb:PPP3R1(gene name)|psi-mi:PPP3R1(display_short)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit 1(gene name synonym)|uniprotkb:Protein phosphatase 3 regulatory subunit B alpha isoform 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000936.1|dip:DIP-6096N|ensembl:ENSG00000221823(gene)|ensembl:ENST00000234310(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007507"(heart development)|go:"GO:0008597"(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0042383"(sarcolemma)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015757(Calcineurin B protein)|interpro:IPR018247|mint:P63098|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2P6B|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4OR9|rcsb pdb:4ORA|rcsb pdb:4ORC|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|reactome:R-HSA-111447|reactome:R-HSA-180024|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:RqM4Q9x8EiLx7CyoF2Rvjl5RddM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O95861 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1055095|uniprotkb:Q8WVL5|uniprotkb:Q9UGJ3|uniprotkb:A8K7C8|uniprotkb:D3DTA9|uniprotkb:B4DPS5|uniprotkb:B4DUS9|ensembl:ENSP00000318852|ensembl:ENSP00000446828 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:bpnt1_human(display_long)|uniprotkb:Bisphosphate 3'-nucleotidase 1(gene name synonym)|uniprotkb:BPNT1(gene name)|psi-mi:BPNT1(display_short)|uniprotkb:PAP-inositol 1,4-phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006076.4|refseq:NP_001273078.1|refseq:NP_001273079.1|refseq:XP_005273057.1|refseq:NP_001273080.1|ensembl:ENSG00000162813(gene)|ensembl:ENST00000322067(transcript)|ensembl:ENST00000469520(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008441"("3'(2'),5'-bisphosphate nucleotidase activity")|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|rcsb pdb:2WEF|reactome:R-HSA-156584|refseq:XP_016855532.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:sMaU5Z6Qy2J2O7bTcoR3gRyHNik9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P60709 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:B4DRT3 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287252 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:b4drt3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR036918|interpro:IPR015806(Pyruvate kinase, beta-barrel)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0016301"(kinase activity)|interpro:IPR040442 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:zT6hsqLrYD3Brbi5hSb/oAZPr5U9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q6PNN2 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4286962 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:q6pnn2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0030030"(cell projection organization)|go:"GO:0042995"(cell projection)|interpro:IPR026201 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:cPf8DSDBzVTt28sVdD+gs39EuEU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9BQS8 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2869338|uniprotkb:Q96IV5|uniprotkb:Q3MJE6|uniprotkb:Q8TEF9|uniprotkb:Q86T41|uniprotkb:Q9H8P9|uniprotkb:Q86TB1|uniprotkb:B7ZKT7|ensembl:ENSP00000296137 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:fyco1_human(display_long)|uniprotkb:FYCO1(gene name)|psi-mi:FYCO1(display_short)|uniprotkb:ZFYVE7(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011532413.1|refseq:XP_006713396.1|refseq:XP_006713397.1|refseq:NP_078789.2|ensembl:ENSG00000163820(gene)|ensembl:ENST00000296137(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR009038(GOLD)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036598|interpro:IPR037213|interpro:IPR042654|mint:Q9BQS8|rcsb pdb:5CX3|rcsb pdb:5D94|rcsb pdb:7BQI|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|dip:DIP-60600N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/iOQiItN7ljXD08DN8DvQ1m6t0E9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q14257 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P53794 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2372138|uniprotkb:O43489|ensembl:ENSP00000370543 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:sc5a3_human(display_long)|uniprotkb:SLC5A3(gene name)|psi-mi:SLC5A3(display_short)|uniprotkb:Solute carrier family 5 member 3(gene name synonym)|uniprotkb:Sodium/myo-inositol transporter 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000198743(gene)|ensembl:ENST00000381151(transcript)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005367"("myo-inositol:sodium symporter activity")|go:"GO:0005412"("glucose:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015150"(fucose transmembrane transporter activity)|go:"GO:0015166"(polyol transmembrane transporter activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015750"(pentose transmembrane transport)|go:"GO:0015756"(fucose transmembrane transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904659"(glucose transmembrane transport)|go:"GO:1904679"(myo-inositol import across plasma membrane)|interpro:IPR001734(Na+/solute symporter)|interpro:IPR018212|interpro:IPR038377|interpro:IPR042731|reactome:R-HSA-429593|go:"GO:1905477"(positive regulation of protein localization to membrane) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:16KjzuPgIn4lcLI9JmRkRFCLe489606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9Y376 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P60174 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P20916 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4286918|ensembl:ENSP00000376048|uniprotkb:Q567S4|uniprotkb:Q15489|uniprotkb:B7Z2E5|uniprotkb:F5GYC0 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:mag_human(display_long)|uniprotkb:MAG(gene name)|psi-mi:MAG(display_short)|uniprotkb:GMA(gene name synonym)|uniprotkb:Siglec-4a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002352.1|ensembl:ENSG00000105695(gene)|ensembl:ENST00000392213(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097453"(mesaxon)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-193634|reactome:R-HSA-210991|reactome:R-HSA-9619665|refseq:NP_001186145.1|refseq:NP_542167.1|dip:DIP-58523N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:VTogoUO14/bXggl3ZPsQzSRo3jM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P49720 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P52209 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P61086 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|ensembl:ENSG00000078140(gene)|ensembl:ENST00000261427(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P22626 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P07954 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P50402 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q86W54 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-3916986|ensembl:ENSP00000414920 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:spa24_human(display_long)|uniprotkb:SPATA24(gene name)|psi-mi:SPATA24(display_short)|uniprotkb:Testis protein T6441 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_919272.1|ensembl:ENSG00000170469(gene)|ensembl:ENST00000450845(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR029176|mint:Q86W54 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:zRwpML9yvh4zUHYw4SSGyJAEHek9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P25786 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P13489 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q13137 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N psi-mi:"MI:0469"(intact) - crc64:609B121DA1A9DCB8 figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q71U36 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P35579 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P31150 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-946999|uniprotkb:P50394|uniprotkb:Q7Z2G6|uniprotkb:Q7Z2G9|uniprotkb:Q7Z2H5|uniprotkb:Q7Z2I6|uniprotkb:Q6FG50|ensembl:ENSP00000394071 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gdia_human(display_long)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:OPHN2(gene name synonym)|uniprotkb:RABGDIA(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 1(gene name synonym)|uniprotkb:Oligophrenin-2(gene name synonym)|uniprotkb:Protein XAP-4(gene name synonym)|uniprotkb:GDIL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001484.1|ensembl:ENSG00000203879(gene)|ensembl:ENST00000447750(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P31150|reactome:R-HSA-8876198 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:bE8RgEdzf7V/T+hWdGJkM9WM0yI9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q13404 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1050671|uniprotkb:Q13403|uniprotkb:Q13532|uniprotkb:Q96H34|uniprotkb:Q9GZT0|uniprotkb:Q9GZW1|uniprotkb:Q9H4J3|uniprotkb:Q9H4J4|uniprotkb:Q9UKL1|uniprotkb:Q9UM48|uniprotkb:Q9UM49|uniprotkb:Q9UM50|uniprotkb:Q5TGE3|uniprotkb:E1P629|uniprotkb:Q5TGE0|ensembl:ENSP00000360739 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ub2v1_human(display_long)|uniprotkb:CROC-1(gene name synonym)|uniprotkb:TRAF6-regulated IKK activator 1 beta Uev1A(gene name synonym)|uniprotkb:P/OKcl.19(orf name)|uniprotkb:UBE2V1(gene name)|psi-mi:UBE2V1(display_short)|uniprotkb:CROC1(gene name synonym)|uniprotkb:UBE2V(gene name synonym)|uniprotkb:UEV1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001027459.1|refseq:NP_068823.2|refseq:NP_071887.1|refseq:NP_954595.1|refseq:NP_954673.1|refseq:NP_001244322.1|refseq:NP_001244323.1|refseq:NP_001244325.1|ensembl:ENSG00000244687(gene)|ensembl:ENST00000371674(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2A4D|rcsb pdb:2C2V|rcsb pdb:2HLW|rcsb pdb:6D6I|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|dip:DIP-41911N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:x95N7Dj2KIqu5gySX59xLmfthUg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P28074 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P19474 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q92777 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4286893|uniprotkb:A8MY98|uniprotkb:A0A087WW96|uniprotkb:A0A087X2E3|ensembl:ENSP00000480050 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:syn2_human(display_long)|uniprotkb:SYN2(gene name)|psi-mi:SYN2(display_short)|uniprotkb:Synapsin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_598328.1|refseq:NP_003169.2|ensembl:ENSG00000157152(gene)|ensembl:ENST00000621198(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028712|reactome:R-HSA-181429|reactome:R-HSA-212676 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:VCVHCPzhfryOA+YZ9JZcUk90mic9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P20618 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9Y6N5 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1170418|uniprotkb:Q9UQM8|ensembl:ENSP00000260324|ensembl:ENSP00000456019 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:sqor_human(display_long)|uniprotkb:SQOR(gene name)|psi-mi:SQOR(display_short)|uniprotkb:SQRDL(gene name synonym)|uniprotkb:Sulfide quinone oxidoreductase(gene name synonym)|uniprotkb:CGI-44(orf name)|uniprotkb:Sulfide dehydrogenase-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_067022.1|refseq:NP_001258142.1|ensembl:ENSG00000137767(gene)|ensembl:ENST00000260324(transcript)|ensembl:ENST00000568606(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0048038"(quinone binding)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0070224"("sulfide:quinone oxidoreductase activity")|go:"GO:0070813"(hydrogen sulfide metabolic process)|go:"GO:0071949"(FAD binding)|interpro:IPR015904(Sulphide quinone-reductase)|interpro:IPR023753|interpro:IPR036188|mint:Q9Y6N5|rcsb pdb:6MO6|rcsb pdb:6MP5|rcsb pdb:6OI5|rcsb pdb:6OI6|rcsb pdb:6OIB|rcsb pdb:6OIC|rcsb pdb:6WH6|reactome:R-HSA-1614517 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:bjOY0YAzon+joBQnCx3q9YvSHh49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P52597 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P49721 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q16637 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P69905 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-714680|uniprotkb:P01922|ensembl:ENSP00000251595|ensembl:ENSP00000322421|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000188536(gene)|ensembl:ENSG00000206172(gene)|ensembl:ENST00000251595(transcript)|ensembl:ENST00000320868(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0016020"(membrane)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:4N7N|rcsb pdb:6KAU|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:6KAV|rcsb pdb:4N8T|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:7AEU|refseq:NP_000508.1|refseq:NP_000549.1|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|dip:DIP-35199N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O94822 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P21757 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1776976|uniprotkb:P21759|uniprotkb:Q45F10|uniprotkb:O60505|uniprotkb:D3DSP3|ensembl:ENSP00000262101 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:msre_human(display_long)|uniprotkb:MSR1(gene name)|psi-mi:MSR1(display_short)|uniprotkb:SCARA1(gene name synonym)|uniprotkb:Macrophage acetylated LDL receptor I and II(gene name synonym)|uniprotkb:Scavenger receptor class A member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002436.1|refseq:NP_619729.1|refseq:NP_619730.1|ensembl:ENSG00000038945(gene)|ensembl:ENST00000262101(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005581"(collagen trimer)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097242"(amyloid-beta clearance)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR003543(Macrophage scavenger receptor)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|mint:P21757|reactome:R-HSA-3000480 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:4IGV7T0fw+Y2rwPdICqixuiOM809606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P09488 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350409|uniprotkb:Q5GHG0|uniprotkb:Q6FH88|uniprotkb:Q9UC96|uniprotkb:Q8TC98|ensembl:ENSP00000311469 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gstm1_human(display_long)|uniprotkb:GSTM1(gene name)|psi-mi:GSTM1(display_short)|uniprotkb:GST1(gene name synonym)|uniprotkb:GSTM1-1(gene name synonym)|uniprotkb:GST class-mu 1(gene name synonym)|uniprotkb:GSTM1a-1a(gene name synonym)|uniprotkb:GSTM1b-1b(gene name synonym)|uniprotkb:GST HB subunit 4(gene name synonym)|uniprotkb:GTH4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000552.2|refseq:NP_666533.1|ensembl:ENSG00000134184(gene)|ensembl:ENST00000309851(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:1901687"(glutathione derivative biosynthetic process)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR040079|rcsb pdb:1GTU|rcsb pdb:1XW6|rcsb pdb:1XWK|rcsb pdb:1YJ6|rcsb pdb:2F3M|reactome:R-HSA-156590 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:/cuHGWU57I+yHHaJM99UyWcAy4c9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P25788 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q86VI3 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1237354|uniprotkb:Q5T3H8|ensembl:ENSP00000354451 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:iqga3_human(display_long)|uniprotkb:IQGAP3(gene name)|psi-mi:IQGAP3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_839943.2|ensembl:ENSP00000354451|ensembl:ENSG00000183856(gene)|ensembl:ENST00000361170(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051015"(actin filament binding)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070856"(myosin VI light chain binding)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|mint:Q86VI3|rcsb pdb:3ISU|reactome:R-HSA-5626467|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:5lIYEC2lJihenWFio0Q+1W9EINI9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P05937 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4286943|ensembl:ENSP00000265431|uniprotkb:B2R696|uniprotkb:B7Z9J4 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:calb1_human(display_long)|uniprotkb:CALB1(gene name)|psi-mi:CALB1(display_short)|uniprotkb:CAB27(gene name synonym)|uniprotkb:Calbindin D28(gene name synonym)|uniprotkb:D-28K(gene name synonym)|uniprotkb:Vitamin D-dependent calcium-binding protein, avian-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_004920.1|ensembl:ENSG00000104327(gene)|ensembl:ENST00000265431(transcript)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032420"(stereocilium)|go:"GO:0032437"(cuticular plate)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072286"(metanephric connecting tubule development)|go:"GO:0090102"(cochlea development)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099509"(regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099534"(calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:0099567"(calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029634|mint:P05937|rcsb pdb:6FIE|reactome:R-HSA-977225|go:"GO:0070062"(extracellular exosome) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:S3jodLzzy/H4m54+NByk9V/e45c9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9BQE3 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P31946 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P11021 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P09936 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O95995 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1052570|uniprotkb:Q2M234|uniprotkb:B2RCT1|ensembl:ENSP00000268699|uniprotkb:B7Z4U1|uniprotkb:G3V1L5 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:drc4_human(display_long)|uniprotkb:Growth arrest-specific protein 11(gene name synonym)|uniprotkb:DRC4(gene name synonym)|uniprotkb:Growth arrest-specific protein 8(gene name synonym)|uniprotkb:GAS8(gene name)|psi-mi:GAS8(display_short)|uniprotkb:GAS11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001472.1|refseq:NP_001273134.1|refseq:NP_001273137.1|refseq:NP_001273138.1|ensembl:ENST00000268699(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035082"(axoneme assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060294"(cilium movement involved in cell motility)|go:"GO:1903566"(positive regulation of protein localization to cilium)|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR025593|interpro:IPR039308|reactome:R-HSA-5635838|refseq:XP_005256361.1|ensembl:ENSG00000141013(gene) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:pQB1v6tXNOzPHL3RdosB397LKDM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P12532 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P38646 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O15027 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O15123 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2912111|ensembl:ENSP00000314897|uniprotkb:B7ZLM7|uniprotkb:A0AV38|uniprotkb:A8K205|uniprotkb:Q9NRR7|uniprotkb:Q9P2Y7 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:angp2_human(display_long)|uniprotkb:ANGPT2(gene name)|psi-mi:ANGPT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000091879(gene)|ensembl:ENST00000325203(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0010467"(gene expression)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042995"(cell projection)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048014"(Tie signaling pathway)|go:"GO:0050928"(negative regulation of positive chemotaxis)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072012"(glomerulus vasculature development)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR028844|interpro:IPR036056|rcsb pdb:1Z3S|rcsb pdb:1Z3U|rcsb pdb:4ZFG|rcsb pdb:2GY7|reactome:R-HSA-210993|rcsb pdb:4JZC|refseq:NP_001112359.1|refseq:NP_001112360.1|refseq:NP_001138.1|dip:DIP-6048N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:p1gSsi5cIt3Lp6o5fA4fVAtvZD49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P00558 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P63027 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-520113|uniprotkb:P19065|ensembl:ENSP00000314214|uniprotkb:Q9BUC2 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_055047.2|ensembl:ENSG00000220205(gene)|ensembl:ENST00000316509(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0043621"(protein self-association)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P61106 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_057406.2|ensembl:ENSG00000119396(gene)|ensembl:ENST00000373840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q15691 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P68366 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P62820 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286|ensembl:ENSP00000497078 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_004152.1|refseq:NP_056358.1|ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045296"(cadherin binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-1063N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O75487 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-3050469|uniprotkb:B4E2C0|ensembl:ENSP00000359864|uniprotkb:B2R6J7|uniprotkb:Q9UPD9|uniprotkb:Q96L43|uniprotkb:Q9NU08|uniprotkb:Q6ZMA6|uniprotkb:Q9UJN1 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:gpc4_human(display_long)|uniprotkb:GPC4(gene name)|psi-mi:GPC4(display_short)|uniprotkb:K-glypican(gene name synonym)|uniprotkb:UNQ474/PRO937(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000076716(gene)|ensembl:ENST00000370828(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|mint:O75487|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1904929"(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001863(Glypican)|interpro:IPR019803|interpro:IPR031180|go:"GO:0016055"(Wnt signaling pathway)|refseq:NP_001439.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:6IC3ItqIRoNTmnS+hi/U34DlXN09606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P55809 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2687150|uniprotkb:B7Z528|uniprotkb:B2R5V2|ensembl:ENSP00000196371 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:scot1_human(display_long)|uniprotkb:OXCT(gene name synonym)|uniprotkb:SCOT(gene name synonym)|uniprotkb:OXCT1(gene name)|psi-mi:OXCT1(display_short)|uniprotkb:3-oxoacid CoA-transferase 1(gene name synonym)|uniprotkb:"Somatic-type succinyl-CoA:3-oxoacid CoA-transferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000427.1|ensembl:ENSG00000083720(gene)|ensembl:ENST00000196371(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042182"(ketone catabolic process)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|rcsb pdb:3DLX|reactome:R-HSA-77108 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:9kyVQbY3sPBRAfJkkF5HhHZg31c9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P06732 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287089|uniprotkb:Q96QL9|ensembl:ENSP00000221476 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:kcrm_human(display_long)|uniprotkb:CKM(gene name)|psi-mi:CKM(display_short)|uniprotkb:CKMM(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001815.2|ensembl:ENSG00000104879(gene)|ensembl:ENST00000221476(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P06732|rcsb pdb:1I0E|reactome:R-HSA-71288|go:"GO:0005524"(ATP binding)|refseq:XP_016881729.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:zuj1pG+YNft6wFPHLPoS+CTamkE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P18669 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002620.1|ensembl:ENSG00000171314(gene)|ensembl:ENST00000334828(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1LJD|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P07437 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P46821 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O43852 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q13885 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P63167 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q15286 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-722275|uniprotkb:B4E390|uniprotkb:B2R6E0|ensembl:ENSP00000229340 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rab35_human(display_long)|uniprotkb:Ras-related protein Rab-1C(gene name synonym)|uniprotkb:GTP-binding protein RAY(gene name synonym)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short)|uniprotkb:RAB1C(gene name synonym)|uniprotkb:RAY(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001161078.1|refseq:NP_006852.1|ensembl:ENSG00000111737(gene)|ensembl:ENST00000229340(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q15286|rcsb pdb:3TW8|rcsb pdb:6EKK|rcsb pdb:6IF2|rcsb pdb:6IF3|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P81605 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P63208 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q12797 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q7Z3V4 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287135|uniprotkb:A5D8Z3|uniprotkb:Q05BX9|uniprotkb:Q659F7|uniprotkb:Q7Z7Q1|uniprotkb:Q9BXZ4|ensembl:ENSP00000340596|ensembl:ENSP00000391529 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ube3b_human(display_long)|uniprotkb:UBE3B(gene name)|psi-mi:UBE3B(display_short)|uniprotkb:HECT-type ubiquitin transferase E3B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:XP_011537261.1|refseq:NP_569733.2|refseq:NP_904324.1|ensembl:ENSG00000151148(gene)|ensembl:ENST00000342494(transcript)|ensembl:ENST00000434735(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|reactome:R-HSA-983168|refseq:NP_001257378.1|refseq:NP_001257379.1|refseq:NP_001257380.1|refseq:XP_005254044.1|refseq:XP_016875685.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:ks96IQ9RKSYamO00r2s2H257Jzk9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P28072 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P43034 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q9UHV9 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q05193 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q96E17 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-4287022|ensembl:ENSP00000282878 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:rab3c_human(display_long)|uniprotkb:RAB3C(gene name)|psi-mi:RAB3C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_612462.1|refseq:NP_001304844.1|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|rcsb pdb:6Y7G|reactome:R-HSA-8873719|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|ensembl:ENSG00000152932(gene)|ensembl:ENST00000282878(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:6wwv7VA89TJogvPAQsfBKLkk4Hc9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O95470 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q13011 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-711968|ensembl:ENSP00000221418|ensembl:ENSP00000489530|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|uniprotkb:A8K745 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000104823(gene)|ensembl:ENSG00000282853(gene)|ensembl:ENST00000221418(transcript)|ensembl:ENST00000634245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016020"(membrane)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q13011|rcsb pdb:2VRE|reactome:R-HSA-9033241|refseq:NP_001389.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P07355 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q99436 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:w880QftOor3RdaGvhCup7apz2OM9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:Q06124 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:O95670 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-348290|ensembl:ENSP00000302194|ensembl:ENSP00000372995|ensembl:ENSP00000395436|ensembl:ENSP00000406372|ensembl:ENSP00000406389|ensembl:ENSP00000408670|ensembl:ENSP00000413222|uniprotkb:Q5HYU8|uniprotkb:Q5RJ63|uniprotkb:Q2L6F8|uniprotkb:B5MEF0 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:vatg2_human(display_long)|uniprotkb:Vacuolar proton pump subunit G 2(gene name synonym)|uniprotkb:V-ATPase 13 kDa subunit 2(gene name synonym)|uniprotkb:ATP6V1G2(gene name)|psi-mi:ATP6V1G2(display_short)|uniprotkb:ATP6G(gene name synonym)|uniprotkb:ATP6G2(gene name synonym)|uniprotkb:NG38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 ensembl:ENSG00000206445(gene)|ensembl:ENSG00000213760(gene)|ensembl:ENSG00000226850(gene)|ensembl:ENSG00000227587(gene)|ensembl:ENSG00000230900(gene)|ensembl:ENSG00000234668(gene)|ensembl:ENSG00000234920(gene)|ensembl:ENST00000303892(transcript)|ensembl:ENST00000383503(transcript)|ensembl:ENST00000441959(transcript)|ensembl:ENST00000444088(transcript)|ensembl:ENST00000449748(transcript)|ensembl:ENST00000454370(transcript)|ensembl:ENST00000454889(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|refseq:NP_569730.1|refseq:NP_001191007.1|refseq:NP_612139.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:DhpIQ1blCTqukmVhcceTQIrLrYg9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15051 uniprotkb:P62158 intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|ensembl:ENSP00000311505|uniprotkb:Q3KS08|uniprotkb:Q3KS09 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4286917|imex:IM-16529-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306036.1|refseq:NP_001018864.2|refseq:NP_001018865.2|ensembl:ENSG00000173226(gene)|ensembl:ENST00000310864(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028765|reactome:R-HSA-5620912|interpro:IPR027417 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1, Supp. Fig. 1. Supp. Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2011/06/16 2020/10/21 rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:E7FE9C11C083082D|rigid:qzsBct9tZvjbn8Bya3hskRuzGHU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8CG73 uniprotkb:P59240 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4287722|imex:IM-16529-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:A93478C9329CD2F4|rigid:TYqbGpAIsWucJePEh0Eaqx5D2ZA false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P59240 uniprotkb:Q9QY53 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4394790|imex:IM-16529-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 intact-crc:15D840AD3435B9BF|rigid:heFmindGP7uIxb8wQpfpsbQ10xA false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9QY53 uniprotkb:P59240 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287728|imex:IM-16529-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:83EC97EAF4F2BA38|rigid:KatNuD2OCHh23vBfcHIobsiFsVw false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9QY53 uniprotkb:Q8CG73 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287728|imex:IM-16529-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:83EC97EAF4F2BA38|rigid:KatNuD2OCHh23vBfcHIobsiFsVw false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CG73 uniprotkb:P59240 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4394805|imex:IM-16529-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:96EE83857DAAA574|rigid:TYqbGpAIsWucJePEh0Eaqx5D2ZA false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9QY53 uniprotkb:P59240 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4287714|imex:IM-16529-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:028838C422F090DB|rigid:heFmindGP7uIxb8wQpfpsbQ10xA false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6A078 uniprotkb:Q8BP00 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4287802|imex:IM-16529-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:80EBCF615996E700|rigid:Qu/fxO5uCjP7AEO8JSeJJnzEzhc false ha tag:n-n|sufficient binding region:1-1207 myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6A078 uniprotkb:Q8BP00 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4287898|imex:IM-16529-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:4434069C98DC6EB6|rigid:Qu/fxO5uCjP7AEO8JSeJJnzEzhc false sufficient binding region:1-1207 tandem tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BP00 uniprotkb:O89019 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281337|uniprotkb:O88849 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4287883|imex:IM-16529-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 intact-crc:7D3C79C479565E41|rigid:BymtgbA7vjAF773mQ/H5gZs28dM false myc tag:?-? tandem tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28658 uniprotkb:Q8BP00 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287838|imex:IM-16529-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:670A6DC1F9B74DD1|rigid:PkihGhUx2DdPnhq38l10M1TBLkU false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BP00 uniprotkb:Q8CG73 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 intact:EBI-4281130|ensembl:ENSMUSP00000042702|uniprotkb:G3X958 psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:ftm_mouse(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:Nphp8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:Ftm(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287862|imex:IM-16529-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 ensembl:ENSMUSG00000033282(gene)|ensembl:ENSMUST00000047783(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:0036064"(ciliary basal body)|refseq:NP_775607.2 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 rogid:JL+lpd1mPW2IHg8VdkPvlui9pME10090 intact-crc:50E614BB5AFB32B2|rigid:+Ub6vJLSczQxQevnHcbEmhf+Fcw false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9QY53 uniprotkb:P59240 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4288127|imex:IM-16529-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 intact-crc:90A4A68AE397E07A|rigid:heFmindGP7uIxb8wQpfpsbQ10xA false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5SW45 uniprotkb:Q2MV57 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4281008|uniprotkb:Q6PDZ5|uniprotkb:Q8C0B3|uniprotkb:Q9CXF5|ensembl:ENSMUSP00000159383 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:tect2_mouse(display_long)|uniprotkb:Tctn2(gene name)|psi-mi:Tctn2(display_short)|uniprotkb:Tect2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287812|imex:IM-16529-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 refseq:NP_080762.1|ensembl:ENSMUSG00000118662(gene)|ensembl:ENSMUST00000239501(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0060271"(cilium assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR011677(Protein of unknown function DUF1619)|interpro:IPR040354|reactome:R-MMU-5620912 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2G|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:jTw1eKE4d5C/2Jxeh/AG4kvg96E10090 intact-crc:5102DB83ACF3D942|rigid:+iNCYZDaHEIbgPGPSwFhFaI3Jwk false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5SW45 uniprotkb:Q8K3E5 intact:EBI-4281059|uniprotkb:Q3V3W3|ensembl:ENSMUSP00000043790 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 psi-mi:mks1_mouse(display_long)|uniprotkb:Mks1(gene name)|psi-mi:Mks1(display_short) psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287820|imex:IM-16529-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-MMU-5610787|reactome:R-MMU-5620912|go:"GO:1990403"(embryonic brain development)|ensembl:ENSMUSG00000034121(gene)|ensembl:ENSMUST00000038196(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_001034773.2 interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2G|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:4xB4V21ENUi7nJzr6aMYO8G6QJQ10090 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 intact-crc:A84F10CABB32D735|rigid:FBCg4tlGKkyl1hpiOS6yTd0LKE8 false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9QY53 uniprotkb:Q8BP00 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287846|imex:IM-16529-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:ADFA352B1C870956|rigid:DXvKatW7wagLnxpgYBDAWvOhdPM false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P59240 uniprotkb:Q8BP00 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-4282243|uniprotkb:Q3TNK4|uniprotkb:Q8K306|ensembl:ENSMUSP00000023535 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:iqcb1_mouse(display_long)|uniprotkb:Iqcb1(gene name)|psi-mi:Iqcb1(display_short)|uniprotkb:Kiaa0036(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4287854|imex:IM-16529-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 ensembl:ENSMUSG00000022837(gene)|ensembl:ENSMUST00000023535(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|reactome:R-MMU-5620912|go:"GO:0045171"(intercellular bridge)|refseq:NP_796102.2|refseq:XP_006522310.1|refseq:XP_006522311.1|refseq:XP_006522312.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:KBiqNkYgQhNZDKDfX6rOPoMa8Y810090 intact-crc:DD206DB03012C81C|rigid:DCPeITOlmEIFH6rVNOkT8nY22dw false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O89019 uniprotkb:Q91ZR4 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-4282339|uniprotkb:Q3U498|uniprotkb:Q9D685|ensembl:ENSMUSP00000017549 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:nek8_mouse(display_long)|uniprotkb:Nek8(gene name)|psi-mi:Nek8(display_short)|uniprotkb:Jck(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4288111|imex:IM-16529-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) ensembl:ENSMUSG00000017405(gene)|ensembl:ENSMUST00000017549(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044120|refseq:NP_543125.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:aaLad1nm9yceDiO9kCqZGghKWRc10090 intact-crc:EBFA5134A5463B6E|rigid:ma1FHJNhYFbBDxKu+o5XgOMmOtM false ha tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TNH6 uniprotkb:Q9QY53 intact:EBI-4281522|ensembl:ENSMUSP00000035167|uniprotkb:Q69Z39|uniprotkb:Q8C798|uniprotkb:Q8C7Z3|uniprotkb:Q9D6D1|uniprotkb:D6RHB4|uniprotkb:E9Q5X1|uniprotkb:E9QN29 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 psi-mi:nphp3_mouse(display_long)|uniprotkb:Nphp3(gene name)|psi-mi:Nphp3(display_short)|uniprotkb:Kiaa2000(gene name synonym) psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4288119|imex:IM-16529-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032558(gene)|ensembl:ENSMUST00000035167(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005929"(cilium)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030324"(lung development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-MMU-5624138|go:"GO:0007368"(determination of left/right symmetry)|refseq:NP_082997.3|refseq:NP_766048.1 refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:596ixTZuJYwu4YJl2cPzvG9BvAA10090 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 intact-crc:8A01298A47679D35|rigid:muVpWC4j3Uc8ykPZEChwFpzieXU false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9QY53 uniprotkb:O89019 intact:EBI-77230|uniprotkb:Q9WUZ2|uniprotkb:Q9D7G8|uniprotkb:Q9QZP0 intact:EBI-4281337|uniprotkb:O88849 psi-mi:nphp1_mouse(display_long)|uniprotkb:Nphp1(gene name)|psi-mi:Nphp1(display_short)|uniprotkb:Nph1(gene name synonym) psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4288095|imex:IM-16529-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058598.1|interpro:IPR001452(Src homology-3)|reactome:R-MMU-5620912|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:40OVe25V7X7XdhGLbnn262jSdMw10090 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 intact-crc:3277824564A40BF8|rigid:sB/K1DwIOnF2w29tznFMQKfEFUM false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O89019 uniprotkb:Q8K3E5 intact:EBI-4281337|uniprotkb:O88849 intact:EBI-4280729|uniprotkb:Q7TNV2|uniprotkb:Q9CVY1 psi-mi:invs_mouse(display_long)|uniprotkb:Invs(gene name)|psi-mi:Invs(display_short)|uniprotkb:Inv(gene name synonym)|uniprotkb:Nphp2(gene name synonym)|uniprotkb:Inversion of embryo turning protein(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym) psi-mi:ahi1_mouse(display_long)|uniprotkb:Ahi1(gene name)|psi-mi:Ahi1(display_short)|uniprotkb:Abelson helper integration site 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sang et al. (2011) pubmed:21565611|imex:IM-16529 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4288102|imex:IM-16529-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097546"(ciliary base)|go:"GO:1904108"(protein localization to ciliary inversin compartment)|go:"GO:0001822"(kidney development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region) interpro:IPR036028|interpro:IPR036322|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR035832|reactome:R-MMU-5620912 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/06/16 2014/10/16 rogid:V2BIhC1R+oi7GUm+TYY7REm+HrU10090 rogid:J5ppuQu5jQr/lNEM9r9gIWikLVA10090 intact-crc:012F20C25EE3B23D|rigid:LIRotjK1kiOavgvBZQXCVKbq4rU false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)