#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8SX86 uniprotkb:P12881 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4279765|imex:IM-15812-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:Proteasome subunit alpha type-7 was also identified but could not be ascribed to a single gene product.|figure legend:Fig. 1A, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-testis)|taxid:7227(Drosophila melanogaster) - 2011/06/15 2014/10/16 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 intact-crc:7C272EE04D24DF0D|rigid:tm47YGijBDZHjGbPxSV9zlRsceg false protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8SX86 uniprotkb:Q9V637 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4279765|imex:IM-15812-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:Proteasome subunit alpha type-7 was also identified but could not be ascribed to a single gene product.|figure legend:Fig. 1A, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-testis)|taxid:7227(Drosophila melanogaster) - 2011/06/15 2014/10/16 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:7C272EE04D24DF0D|rigid:tm47YGijBDZHjGbPxSV9zlRsceg false protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8SX86 uniprotkb:P12881 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4279750|imex:IM-15812-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1B, Supp. Fig. 1A|comment:Proteasome subunit alpha type-7 was also identified but could not be ascribed to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2011/06/15 2014/10/16 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 intact-crc:6671ED00F6292202|rigid:tm47YGijBDZHjGbPxSV9zlRsceg false protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8SX86 uniprotkb:Q9V637 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-4279750|imex:IM-15812-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1B, Supp. Fig. 1A|comment:Proteasome subunit alpha type-7 was also identified but could not be ascribed to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2011/06/15 2014/10/16 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:6671ED00F6292202|rigid:tm47YGijBDZHjGbPxSV9zlRsceg false protein a tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9V637 uniprotkb:Q8SX86 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4279879|imex:IM-15812-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2011/06/15 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 intact-crc:0080FC37C354DBA7|rigid:4Lc5vAFB0U78ovkdqOrxA8jxOC4 false - mutation decreasing interaction:188-188|protein a tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8SX86 uniprotkb:Q9V637 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-4279895|imex:IM-15812-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/06/15 2014/10/16 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:33ED83FDE623F89C|rigid:4Lc5vAFB0U78ovkdqOrxA8jxOC4 false green fluorescent protein tag:?-? necessary binding region:1-100|ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9V637 uniprotkb:Q8SX86 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-137714|uniprotkb:Q9VZM8|intact:EBI-1628428|ensemblmetazoa:FBpp0073041 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:nutc_drome(display_long)|uniprotkb:CG10855(orf name)|uniprotkb:ntc(gene name)|psi-mi:ntc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bader et al. (2011) pubmed:21529711|imex:IM-15812 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4279861|imex:IM-15812-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBgn0035461(gene)|ensemblmetazoa:FBtr0073185(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|refseq:NP_647829.1|flybase:FBgn0035461|dip:DIP-18929N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1D, 3C|comment:Ntc also interacted with proteasome subunit alpha7 but this could not be ascribed to a single gene product.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-testis)|taxid:7227(Drosophila melanogaster) - 2011/06/15 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:msSRR3D8lb7ZFB3h3wGYC0M59oM7227 intact-crc:25D8C5170117625C|rigid:4Lc5vAFB0U78ovkdqOrxA8jxOC4 false - protein a tag:?-?|sufficient binding region:1-256 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)