#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P56546	uniprotkb:Q9HAZ2-2	intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269	intact:EBI-5282871|ensembl:ENSP00000367643	psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short)	psi-mi:q9haz2-2(display_long)|uniprotkb:MEL1L(isoform synonym)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nishikata et al. (2011)	pubmed:21516122|imex:IM-16582	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-5240188|imex:IM-16582-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265	intact:EBI-2795620(isoform-parent)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000378391(transcript)|uniprotkb:Q9HAZ2-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:3b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/10/18	2014/10/16	rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090	rogid:Q4MDppTIh9yCUj4ZHnyU+dkF4Go9606	intact-crc:0B5921211BE80B4F|rigid:+/3tn0kRmnnVcqGYH6XFD18Ek8I	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56546	uniprotkb:Q9HAZ2-2	intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269	intact:EBI-5282871|ensembl:ENSP00000367643	psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short)	psi-mi:q9haz2-2(display_long)|uniprotkb:MEL1L(isoform synonym)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nishikata et al. (2011)	pubmed:21516122|imex:IM-16582	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-4566671|imex:IM-16582-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265	intact:EBI-2795620(isoform-parent)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000378391(transcript)|uniprotkb:Q9HAZ2-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:3b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/10/18	2014/10/16	rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090	rogid:Q4MDppTIh9yCUj4ZHnyU+dkF4Go9606	intact-crc:83ECC52312E84295|rigid:+/3tn0kRmnnVcqGYH6XFD18Ek8I	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HAZ2-4	uniprotkb:P56546	intact:EBI-4566658	intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269	psi-mi:q9haz2-4(display_long)|uniprotkb:MEL1S(isoform synonym)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)	psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nishikata et al. (2011)	pubmed:21516122|imex:IM-16582	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-5240232|imex:IM-16582-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2795620(isoform-parent)	refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265	psi-mi:"MI:0469"(intact)	isoform-comment:Produced by alternative promoter usage.	-	figure legend:3b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/10/18	2014/10/16	rogid:atA5lWTyHBIB6IVqAlRpIZnPvy09606	rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090	intact-crc:C82CB1726B7D5D3A|rigid:OMAY4jWYZDC8M1TkltFTW30//W0	false	mutation disrupting interaction:590-591,620-621|ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56546	uniprotkb:Q9HAZ2-4	intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269	intact:EBI-4566658	psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short)	psi-mi:q9haz2-4(display_long)|uniprotkb:MEL1S(isoform synonym)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nishikata et al. (2011)	pubmed:21516122|imex:IM-16582	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-5240217|imex:IM-16582-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265	intact:EBI-2795620(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Produced by alternative promoter usage.	figure legend:3b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/10/18	2014/10/16	rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090	rogid:atA5lWTyHBIB6IVqAlRpIZnPvy09606	intact-crc:878892216253D6A1|rigid:OMAY4jWYZDC8M1TkltFTW30//W0	false	flag tag:?-?	mutation disrupting interaction:590-591,620-621|ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56519	uniprotkb:Q9HAZ2-4	intact:EBI-5240354	intact:EBI-4566658	psi-mi:hdac2_chick(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short)	psi-mi:q9haz2-4(display_long)|uniprotkb:MEL1S(isoform synonym)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nishikata et al. (2011)	pubmed:21516122|imex:IM-16582	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-5240370|imex:IM-16582-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023801|interpro:IPR023696|interpro:IPR037138|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0140297"(DNA-binding transcription factor binding)	intact:EBI-2795620(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Produced by alternative promoter usage.	figure legend:6b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/10/18	2014/10/16	rogid:NRK1bqOH8i3gMaXHhezP7tcUX5o9031	rogid:atA5lWTyHBIB6IVqAlRpIZnPvy09606	intact-crc:19458A23EACD9AA1|rigid:lELusI9Lp5pgtXCxmDr3Zn1WkF8	false	flag tag:?-?	green fluorescent protein tag:?-?|sufficient binding region:523-644|mutation decreasing interaction:568-568,590-590,591-591,619-619,620-620|mutation decreasing interaction:568-568|mutation decreasing interaction:590-590,591-591,621-621,620-620	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)