#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8WTY4 uniprotkb:Q9CQM9 intact:EBI-2943068|ensembl:ENSMUSP00000034233|ensembl:ENSMUSP00000125451|uniprotkb:Q3UJW5|uniprotkb:Q8VC24|uniprotkb:Q91W83 intact:EBI-4319195|uniprotkb:Q5I0V8|uniprotkb:Q9JLZ2|ensembl:ENSMUSP00000066621 psi-mi:cpin1_mouse(display_long)|uniprotkb:Ciapin1(gene name)|psi-mi:Ciapin1(display_short)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym) psi-mi:glrx3_mouse(display_long)|uniprotkb:Glrx3(gene name)|psi-mi:Glrx3(display_short)|uniprotkb:Picot(gene name synonym)|uniprotkb:Txnl2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:Thioredoxin-like protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Saito et al. (2011) pubmed:21513700|imex:IM-16962 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319223|imex:IM-16962-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031781(gene)|ensembl:ENSMUST00000034233(transcript)|ensembl:ENSMUST00000162538(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|mint:Q8WTY4|refseq:NP_598902.1|refseq:XP_006530623.1 refseq:NP_075629.2|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:Q9CQM9|rcsb pdb:1WIK|ensembl:ENSMUSG00000031068(gene)|ensembl:ENSMUST00000064404(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding) - - - figure legend:Supplementary Fig. 1 and 2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:EOs26WzjhhOQJfL4YSSB1Y9So5s10090 rogid:fgDgQ7pzk+HxZeHtXPTSCf5FShM10090 intact-crc:E807C4CC20E960BC|rigid:5VIwODump8Ae7mvafAuYmmmuBQg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WTY4 uniprotkb:Q9CQM9 intact:EBI-2943068|ensembl:ENSMUSP00000034233|ensembl:ENSMUSP00000125451|uniprotkb:Q3UJW5|uniprotkb:Q8VC24|uniprotkb:Q91W83 intact:EBI-4319195|uniprotkb:Q5I0V8|uniprotkb:Q9JLZ2|ensembl:ENSMUSP00000066621 psi-mi:cpin1_mouse(display_long)|uniprotkb:Ciapin1(gene name)|psi-mi:Ciapin1(display_short)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym) psi-mi:glrx3_mouse(display_long)|uniprotkb:Glrx3(gene name)|psi-mi:Glrx3(display_short)|uniprotkb:Picot(gene name synonym)|uniprotkb:Txnl2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:Thioredoxin-like protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Saito et al. (2011) pubmed:21513700|imex:IM-16962 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319246|imex:IM-16962-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031781(gene)|ensembl:ENSMUST00000034233(transcript)|ensembl:ENSMUST00000162538(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|mint:Q8WTY4|refseq:NP_598902.1|refseq:XP_006530623.1 refseq:NP_075629.2|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:Q9CQM9|rcsb pdb:1WIK|ensembl:ENSMUSG00000031068(gene)|ensembl:ENSMUST00000064404(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding) - - - figure legend:Figure 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/02 2014/10/16 rogid:EOs26WzjhhOQJfL4YSSB1Y9So5s10090 rogid:fgDgQ7pzk+HxZeHtXPTSCf5FShM10090 intact-crc:0F2C889E5FFA58A8|rigid:5VIwODump8Ae7mvafAuYmmmuBQg false flag tag:?-? sufficient binding region:1-146|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WTY4 uniprotkb:Q9CQM9 intact:EBI-2943068|ensembl:ENSMUSP00000034233|ensembl:ENSMUSP00000125451|uniprotkb:Q3UJW5|uniprotkb:Q8VC24|uniprotkb:Q91W83 intact:EBI-4319195|uniprotkb:Q5I0V8|uniprotkb:Q9JLZ2|ensembl:ENSMUSP00000066621 psi-mi:cpin1_mouse(display_long)|uniprotkb:Ciapin1(gene name)|psi-mi:Ciapin1(display_short)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym) psi-mi:glrx3_mouse(display_long)|uniprotkb:Glrx3(gene name)|psi-mi:Glrx3(display_short)|uniprotkb:Picot(gene name synonym)|uniprotkb:Txnl2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:Thioredoxin-like protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saito et al. (2011) pubmed:21513700|imex:IM-16962 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319273|imex:IM-16962-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031781(gene)|ensembl:ENSMUST00000034233(transcript)|ensembl:ENSMUST00000162538(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|mint:Q8WTY4|refseq:NP_598902.1|refseq:XP_006530623.1 refseq:NP_075629.2|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:Q9CQM9|rcsb pdb:1WIK|ensembl:ENSMUSG00000031068(gene)|ensembl:ENSMUST00000064404(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding) - - - figure legend:Figure 1C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ba_f3)|taxid:10090(Mouse pro B cells IL-3 dependent) - 2011/08/02 2014/10/16 rogid:EOs26WzjhhOQJfL4YSSB1Y9So5s10090 rogid:fgDgQ7pzk+HxZeHtXPTSCf5FShM10090 intact-crc:31EC8B84F0AF0B38|rigid:5VIwODump8Ae7mvafAuYmmmuBQg false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9CQM9 uniprotkb:Q8WTY4 intact:EBI-4319195|uniprotkb:Q5I0V8|uniprotkb:Q9JLZ2|ensembl:ENSMUSP00000066621 intact:EBI-2943068|ensembl:ENSMUSP00000034233|ensembl:ENSMUSP00000125451|uniprotkb:Q3UJW5|uniprotkb:Q8VC24|uniprotkb:Q91W83 psi-mi:glrx3_mouse(display_long)|uniprotkb:Glrx3(gene name)|psi-mi:Glrx3(display_short)|uniprotkb:Picot(gene name synonym)|uniprotkb:Txnl2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:Thioredoxin-like protein 2(gene name synonym) psi-mi:cpin1_mouse(display_long)|uniprotkb:Ciapin1(gene name)|psi-mi:Ciapin1(display_short)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Saito et al. (2011) pubmed:21513700|imex:IM-16962 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4399362|imex:IM-16962-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075629.2|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:Q9CQM9|rcsb pdb:1WIK|ensembl:ENSMUSG00000031068(gene)|ensembl:ENSMUST00000064404(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding) ensembl:ENSMUSG00000031781(gene)|ensembl:ENSMUST00000034233(transcript)|ensembl:ENSMUST00000162538(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|mint:Q8WTY4|refseq:NP_598902.1|refseq:XP_006530623.1 - - - figure legend:Supplementary Figure 1 and 2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:fgDgQ7pzk+HxZeHtXPTSCf5FShM10090 rogid:EOs26WzjhhOQJfL4YSSB1Y9So5s10090 intact-crc:85A928B717B31673|rigid:5VIwODump8Ae7mvafAuYmmmuBQg false necessary binding region:19-118 necessary binding region:12-181 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)