#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P40343	uniprotkb:P25604	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630175|mint:MINT-8187942|imex:IM-15427-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8187945(identity)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8187944(identity)	-	crc64:76C4501B0EBC9C84	crc64:FEDE3BE79F063BCE	comment:homomint|comment:domino|comment:mint|comment:"PDB Accession : 3R42"|figure legend:t1 f2a f2b f2d f2e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/17	2014/10/16	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	intact-crc:D5E802132956E189|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	binding-associated region:445-453(MINT-8187954)	binding-associated region:1-160(MINT-8187949)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25604	uniprotkb:P40343	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630205|mint:MINT-8187963|imex:IM-15427-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8187965(identity)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8187970(identity)	-	crc64:FEDE3BE79F063BCE	crc64:76C4501B0EBC9C84	figure legend:F3A F3C|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:8.4x10^-5(molar)	2011/06/17	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	intact-crc:728AEEBC03897774|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	mutation disrupting interaction:16-16(MINT-8187978)|binding-associated region:1-160(MINT-8187966)	binding-associated region:445-453(MINT-8187971)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P40343	uniprotkb:P25604	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630255|mint:MINT-8188001|imex:IM-15427-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8188011(identity)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8188004(identity)	-	crc64:76C4501B0EBC9C84	crc64:FEDE3BE79F063BCE	figure legend:F3C|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.73x10^-4(molar)	2011/06/17	2014/10/16	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	intact-crc:56C316E5241D8CD5|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	binding-associated region:445-453(MINT-8188012)	mutation decreasing interaction:61-61(MINT-8188005)|binding-associated region:1-160(MINT-8188007)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40343	uniprotkb:P25604	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630230|mint:MINT-8187982|imex:IM-15427-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8187992(identity)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8187985(identity)	-	crc64:76C4501B0EBC9C84	crc64:FEDE3BE79F063BCE	figure legend:F3C|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.06x10^-4(molar)	2011/06/17	2014/10/16	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	intact-crc:168F0AFC28E84554|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	binding-associated region:445-453(MINT-8187993)	mutation decreasing interaction:49-49(MINT-8187986)|binding-associated region:1-160(MINT-8187988)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25604	uniprotkb:P40343	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630280|mint:MINT-8188019|imex:IM-15427-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8188022(identity)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8188029(identity)	-	crc64:FEDE3BE79F063BCE	crc64:76C4501B0EBC9C84	figure legend:F3A|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.4x10^-5(molar)	2011/06/17	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	intact-crc:2BF51953C3E78D86|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	binding-associated region:1-160(MINT-8188023)	binding-associated region:521-529(MINT-8188030)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P25604	uniprotkb:P40343	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630325|mint:MINT-8188210|imex:IM-15427-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8188213(identity)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8188218(identity)	-	crc64:FEDE3BE79F063BCE	crc64:76C4501B0EBC9C84	figure legend:F3B|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.72x10^-4(molar)	2011/06/17	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	intact-crc:5B29A885B764418A|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	binding-associated region:1-160(MINT-8188214)	mutation decreasing interaction:525-525(MINT-8188226)|binding-associated region:521-529(MINT-8188221)|fusion protein:?-?(MINT-8188219)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P25604	uniprotkb:P40343	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Ren et al. (2011)	mint:MINT-8187935|pubmed:21505419|imex:IM-15427|doi:10.1038/emboj.2011.122	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8630301|mint:MINT-8188037|imex:IM-15427-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-8188040(identity)	sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343|mint:MINT-8188045(identity)	-	crc64:FEDE3BE79F063BCE	crc64:76C4501B0EBC9C84	figure legend:F3B|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.1x10^-5(molar)	2011/06/17	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:5ScB34gSI3x260kAGh/knEWupwA559292	intact-crc:387C36DBDB316564|rigid:H6qCFvX8pPvh7ptQImBfkC6ZKRk	false	binding-associated region:1-160(MINT-8188041)	fusion protein:?-?(MINT-8188051)|binding-associated region:521-529(MINT-8188046)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)