#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H8M7 uniprotkb:Q92905 intact:EBI-724928|uniprotkb:Q5SZ68|uniprotkb:Q5SZ69|uniprotkb:Q5SZ70|uniprotkb:Q6IA40|uniprotkb:Q6P7P0|uniprotkb:Q7Z2S1|uniprotkb:Q8WUF1|uniprotkb:Q9H3I4|ensembl:ENSP00000277632 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 psi-mi:miny3_human(display_long)|uniprotkb:MSTP126(orf name)|uniprotkb:My042(orf name)|uniprotkb:MINDY3(gene name)|psi-mi:MINDY3(display_short)|uniprotkb:C10orf97(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:DERP5(gene name synonym)|uniprotkb:Dermal papilla-derived protein 5(gene name synonym)|uniprotkb:Deubiquitinating enzyme MINDY-3(gene name synonym)|uniprotkb:FAM188A(gene name synonym)|uniprotkb:Protein CARP(gene name synonym) psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shi et al. (2011) pubmed:21499297|imex:IM-16579 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-4422753|imex:IM-16579-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079224.1|refseq:NP_001305259.1|ensembl:ENSG00000148481(gene)|ensembl:ENST00000277632(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR011992(EF-Hand type)|interpro:IPR025257|interpro:IPR039785|refseq:XP_005252657.1|refseq:XP_005252659.1|refseq:XP_011517996.1|refseq:XP_016872162.1 refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664 psi-mi:"MI:0469"(intact) - - figure legend:5b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2011/10/04 2014/10/16 rogid:g6aEz4py3G+v3v35VsWTf4dXq7U9606 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 intact-crc:73979A4FB6D8D28A|rigid:4K91zYa362YwbX86yX1fQq4ZTSM false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92905 uniprotkb:Q9H8M7 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 intact:EBI-724928|uniprotkb:Q5SZ68|uniprotkb:Q5SZ69|uniprotkb:Q5SZ70|uniprotkb:Q6IA40|uniprotkb:Q6P7P0|uniprotkb:Q7Z2S1|uniprotkb:Q8WUF1|uniprotkb:Q9H3I4|ensembl:ENSP00000277632 psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:miny3_human(display_long)|uniprotkb:MSTP126(orf name)|uniprotkb:My042(orf name)|uniprotkb:MINDY3(gene name)|psi-mi:MINDY3(display_short)|uniprotkb:C10orf97(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:DERP5(gene name synonym)|uniprotkb:Dermal papilla-derived protein 5(gene name synonym)|uniprotkb:Deubiquitinating enzyme MINDY-3(gene name synonym)|uniprotkb:FAM188A(gene name synonym)|uniprotkb:Protein CARP(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shi et al. (2011) pubmed:21499297|imex:IM-16579 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1262"(I2D) intact:EBI-4422773|imex:IM-16579-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664 refseq:NP_079224.1|refseq:NP_001305259.1|ensembl:ENSG00000148481(gene)|ensembl:ENST00000277632(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR011992(EF-Hand type)|interpro:IPR025257|interpro:IPR039785|refseq:XP_005252657.1|refseq:XP_005252659.1|refseq:XP_011517996.1|refseq:XP_016872162.1 psi-mi:"MI:0469"(intact) - - figure legend:5c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2011/10/04 2014/10/16 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 rogid:g6aEz4py3G+v3v35VsWTf4dXq7U9606 intact-crc:92E2F93949092993|rigid:4K91zYa362YwbX86yX1fQq4ZTSM false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9H8M7 uniprotkb:Q92905 intact:EBI-724928|uniprotkb:Q5SZ68|uniprotkb:Q5SZ69|uniprotkb:Q5SZ70|uniprotkb:Q6IA40|uniprotkb:Q6P7P0|uniprotkb:Q7Z2S1|uniprotkb:Q8WUF1|uniprotkb:Q9H3I4|ensembl:ENSP00000277632 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 psi-mi:miny3_human(display_long)|uniprotkb:MSTP126(orf name)|uniprotkb:My042(orf name)|uniprotkb:MINDY3(gene name)|psi-mi:MINDY3(display_short)|uniprotkb:C10orf97(gene name synonym)|uniprotkb:CARP(gene name synonym)|uniprotkb:DERP5(gene name synonym)|uniprotkb:Dermal papilla-derived protein 5(gene name synonym)|uniprotkb:Deubiquitinating enzyme MINDY-3(gene name synonym)|uniprotkb:FAM188A(gene name synonym)|uniprotkb:Protein CARP(gene name synonym) psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shi et al. (2011) pubmed:21499297|imex:IM-16579 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-4422794|imex:IM-16579-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079224.1|refseq:NP_001305259.1|ensembl:ENSG00000148481(gene)|ensembl:ENST00000277632(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR011992(EF-Hand type)|interpro:IPR025257|interpro:IPR039785|refseq:XP_005252657.1|refseq:XP_005252659.1|refseq:XP_011517996.1|refseq:XP_016872162.1 refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664 psi-mi:"MI:0469"(intact) - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/10/04 2014/10/16 rogid:g6aEz4py3G+v3v35VsWTf4dXq7U9606 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 intact-crc:9EF8BA54356777D6|rigid:4K91zYa362YwbX86yX1fQq4ZTSM false gal4 dna binding domain:?-? sufficient binding region:36-334 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)