#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BZ71 uniprotkb:P55774 intact:EBI-2815766|uniprotkb:Q59GH9|uniprotkb:Q9NPQ4|uniprotkb:A1A5D0|uniprotkb:F8WEW5|ensembl:ENSP00000262483 intact:EBI-711240|uniprotkb:Q53X71|ensembl:ENSP00000479955|ensembl:ENSP00000483144|ensembl:ENSP00000483347|uniprotkb:B5BUM2 psi-mi:pitm3_human(display_long)|uniprotkb:PITPNM3(gene name)|psi-mi:PITPNM3(display_short)|uniprotkb:NIR1(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 3(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 1(gene name synonym) psi-mi:ccl18_human(display_long)|uniprotkb:CCL18(gene name)|psi-mi:CCL18(display_short)|uniprotkb:AMAC1(gene name synonym)|uniprotkb:DCCK1(gene name synonym)|uniprotkb:MIP4(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:SCYA18(gene name synonym)|uniprotkb:Dendritic cell chemokine 1(gene name synonym)|uniprotkb:Small-inducible cytokine A18(gene name synonym)|uniprotkb:Macrophage inflammatory protein 4(gene name synonym)|uniprotkb:Pulmonary and activation-regulated chemokine(gene name synonym)|uniprotkb:CC chemokine PARC(gene name synonym)|uniprotkb:Alternative macrophage activation-associated CC chemokine 1(gene name synonym) psi-mi:"MI:0405"(competition binding) Chen et al. (2011) imex:IM-15750|pubmed:21481794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3925924|imex:IM-15750-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112497.2|ensembl:ENSG00000091622(gene)|ensembl:ENST00000262483(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR031315|interpro:IPR036412|reactome:R-HSA-1483226 refseq:NP_002979.1|ensembl:ENSG00000275385(gene)|ensembl:ENSG00000278006(gene)|ensembl:ENSG00000278167(gene)|ensembl:ENST00000614828(transcript)|ensembl:ENST00000615723(transcript)|ensembl:ENST00000616054(transcript)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007154"(cell communication)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4MHE psi-mi:"MI:0469"(intact) - - figure legend:Fig 5C|antagonist:CCL3 and CCL4 with low affinity|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/18 2014/10/16 rogid:7KWZgZGsXcnjne6fAjaVoL9KsSA9606 rogid:kIVbD90ZDYN5T+Vwg5vb1c1UeR09606 intact-crc:046F3D93D4CA8D16|rigid:PsQlWs+jgqlcf8sXAsP+VGqjWDA false - 125i radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55774 uniprotkb:Q9BZ71 intact:EBI-711240|uniprotkb:Q53X71|ensembl:ENSP00000479955|ensembl:ENSP00000483144|ensembl:ENSP00000483347|uniprotkb:B5BUM2 intact:EBI-2815766|uniprotkb:Q59GH9|uniprotkb:Q9NPQ4|uniprotkb:A1A5D0|uniprotkb:F8WEW5|ensembl:ENSP00000262483 psi-mi:ccl18_human(display_long)|uniprotkb:CCL18(gene name)|psi-mi:CCL18(display_short)|uniprotkb:AMAC1(gene name synonym)|uniprotkb:DCCK1(gene name synonym)|uniprotkb:MIP4(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:SCYA18(gene name synonym)|uniprotkb:Dendritic cell chemokine 1(gene name synonym)|uniprotkb:Small-inducible cytokine A18(gene name synonym)|uniprotkb:Macrophage inflammatory protein 4(gene name synonym)|uniprotkb:Pulmonary and activation-regulated chemokine(gene name synonym)|uniprotkb:CC chemokine PARC(gene name synonym)|uniprotkb:Alternative macrophage activation-associated CC chemokine 1(gene name synonym) psi-mi:pitm3_human(display_long)|uniprotkb:PITPNM3(gene name)|psi-mi:PITPNM3(display_short)|uniprotkb:NIR1(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 3(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2011) imex:IM-15750|pubmed:21481794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3925890|imex:IM-15750-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002979.1|ensembl:ENSG00000275385(gene)|ensembl:ENSG00000278006(gene)|ensembl:ENSG00000278167(gene)|ensembl:ENST00000614828(transcript)|ensembl:ENST00000615723(transcript)|ensembl:ENST00000616054(transcript)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007154"(cell communication)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4MHE refseq:NP_112497.2|ensembl:ENSG00000091622(gene)|ensembl:ENST00000262483(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR031315|interpro:IPR036412|reactome:R-HSA-1483226 psi-mi:"MI:0469"(intact) - - figure legend:Fig 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2011/05/18 2014/10/16 rogid:kIVbD90ZDYN5T+Vwg5vb1c1UeR09606 rogid:7KWZgZGsXcnjne6fAjaVoL9KsSA9606 intact-crc:289D328EAD898CE1|rigid:PsQlWs+jgqlcf8sXAsP+VGqjWDA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P55774 uniprotkb:Q9BZ71 intact:EBI-711240|uniprotkb:Q53X71|ensembl:ENSP00000479955|ensembl:ENSP00000483144|ensembl:ENSP00000483347|uniprotkb:B5BUM2 intact:EBI-2815766|uniprotkb:Q59GH9|uniprotkb:Q9NPQ4|uniprotkb:A1A5D0|uniprotkb:F8WEW5|ensembl:ENSP00000262483 psi-mi:ccl18_human(display_long)|uniprotkb:CCL18(gene name)|psi-mi:CCL18(display_short)|uniprotkb:AMAC1(gene name synonym)|uniprotkb:DCCK1(gene name synonym)|uniprotkb:MIP4(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:SCYA18(gene name synonym)|uniprotkb:Dendritic cell chemokine 1(gene name synonym)|uniprotkb:Small-inducible cytokine A18(gene name synonym)|uniprotkb:Macrophage inflammatory protein 4(gene name synonym)|uniprotkb:Pulmonary and activation-regulated chemokine(gene name synonym)|uniprotkb:CC chemokine PARC(gene name synonym)|uniprotkb:Alternative macrophage activation-associated CC chemokine 1(gene name synonym) psi-mi:pitm3_human(display_long)|uniprotkb:PITPNM3(gene name)|psi-mi:PITPNM3(display_short)|uniprotkb:NIR1(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 3(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2011) imex:IM-15750|pubmed:21481794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3925901|imex:IM-15750-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002979.1|ensembl:ENSG00000275385(gene)|ensembl:ENSG00000278006(gene)|ensembl:ENSG00000278167(gene)|ensembl:ENST00000614828(transcript)|ensembl:ENST00000615723(transcript)|ensembl:ENST00000616054(transcript)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007154"(cell communication)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4MHE refseq:NP_112497.2|ensembl:ENSG00000091622(gene)|ensembl:ENST00000262483(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR031315|interpro:IPR036412|reactome:R-HSA-1483226 psi-mi:"MI:0469"(intact) - - figure legend:Fig 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2011/05/18 2014/10/16 rogid:kIVbD90ZDYN5T+Vwg5vb1c1UeR09606 rogid:7KWZgZGsXcnjne6fAjaVoL9KsSA9606 intact-crc:514795564FC069B2|rigid:PsQlWs+jgqlcf8sXAsP+VGqjWDA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BZ71 uniprotkb:P55774 intact:EBI-2815766|uniprotkb:Q59GH9|uniprotkb:Q9NPQ4|uniprotkb:A1A5D0|uniprotkb:F8WEW5|ensembl:ENSP00000262483 intact:EBI-711240|uniprotkb:Q53X71|ensembl:ENSP00000479955|ensembl:ENSP00000483144|ensembl:ENSP00000483347|uniprotkb:B5BUM2 psi-mi:pitm3_human(display_long)|uniprotkb:PITPNM3(gene name)|psi-mi:PITPNM3(display_short)|uniprotkb:NIR1(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 3(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 1(gene name synonym) psi-mi:ccl18_human(display_long)|uniprotkb:CCL18(gene name)|psi-mi:CCL18(display_short)|uniprotkb:AMAC1(gene name synonym)|uniprotkb:DCCK1(gene name synonym)|uniprotkb:MIP4(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:SCYA18(gene name synonym)|uniprotkb:Dendritic cell chemokine 1(gene name synonym)|uniprotkb:Small-inducible cytokine A18(gene name synonym)|uniprotkb:Macrophage inflammatory protein 4(gene name synonym)|uniprotkb:Pulmonary and activation-regulated chemokine(gene name synonym)|uniprotkb:CC chemokine PARC(gene name synonym)|uniprotkb:Alternative macrophage activation-associated CC chemokine 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Chen et al. (2011) imex:IM-15750|pubmed:21481794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3925912|imex:IM-15750-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112497.2|ensembl:ENSG00000091622(gene)|ensembl:ENST00000262483(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR031315|interpro:IPR036412|reactome:R-HSA-1483226 refseq:NP_002979.1|ensembl:ENSG00000275385(gene)|ensembl:ENSG00000278006(gene)|ensembl:ENSG00000278167(gene)|ensembl:ENST00000614828(transcript)|ensembl:ENST00000615723(transcript)|ensembl:ENST00000616054(transcript)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007154"(cell communication)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:4MHE go:"GO:0005886"(plasma membrane) - - figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2011/05/18 2014/10/16 rogid:7KWZgZGsXcnjne6fAjaVoL9KsSA9606 rogid:kIVbD90ZDYN5T+Vwg5vb1c1UeR09606 intact-crc:49FD5E88F03293D6|rigid:PsQlWs+jgqlcf8sXAsP+VGqjWDA false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)