#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O88508 - intact:EBI-995154|uniprotkb:Q3UH24|uniprotkb:Q8CJ60|uniprotkb:Q922J0|uniprotkb:Q9CSE1|uniprotkb:Q3TZK8|ensembl:ENSMUSP00000020991|ensembl:ENSMUSP00000134009 - psi-mi:dnm3a_mouse(display_long)|uniprotkb:DNA methyltransferase MmuIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym)|uniprotkb:Dnmt3a(gene name)|psi-mi:Dnmt3a(display_short) - psi-mi:"MI:0515"(methyltransferase assay) Siddique et al. (2011) mint:MINT-8152121|pubmed:21481189|mint:fj-10-1170.r2 taxid:10090(mouse)|taxid:10090(Mus musculus) - psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8625938|mint:MINT-8152126 - - psi-mi:"MI:0503"(self) - psi-mi:"MI:0503"(self) - psi-mi:"MI:0326"(protein) - go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0046872"(metal ion binding)|go:"GO:0051719"("DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates")|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:O88508|rcsb pdb:3SW9|rcsb pdb:3SWC|reactome:R-MMU-212300|reactome:R-MMU-3214858|ensembl:ENSMUSG00000020661(gene)|ensembl:ENSMUST00000020991(transcript)|ensembl:ENSMUST00000174817(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_031898.1|refseq:NP_714965.1|refseq:XP_006515016.1|refseq:XP_006515019.1|refseq:NP_001258682.1|dip:DIP-38005N|mint:MINT-8152128(identity) - - - - comment:mint|figure legend:f1 f2 f4 sf1 sf2|intra-molecular:true taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/04/04 2014/10/16 rogid:ZLqyo0sbBdWAlvbJ25rm+p58o5810090 - intact-crc:B61424DE2702221F false his tag:?-?(MINT-8152134)|mutation disrupting interaction:706-706(MINT-8152144)|binding-associated region:608-908(MINT-8152137)|methylated residue:706-706(MINT-8152141) - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) - uniprotkb:Q9UJW3 uniprotkb:O88508 intact:EBI-740967|ensembl:ENSP00000486001|uniprotkb:Q9BUJ4|uniprotkb:E9PB42 intact:EBI-995154|uniprotkb:Q3UH24|uniprotkb:Q8CJ60|uniprotkb:Q922J0|uniprotkb:Q9CSE1|uniprotkb:Q3TZK8|ensembl:ENSMUSP00000020991|ensembl:ENSMUSP00000134009 psi-mi:dnm3l_human(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short) psi-mi:dnm3a_mouse(display_long)|uniprotkb:DNA methyltransferase MmuIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym)|uniprotkb:Dnmt3a(gene name)|psi-mi:Dnmt3a(display_short) psi-mi:"MI:0515"(methyltransferase assay) Siddique et al. (2011) mint:MINT-8152121|pubmed:21481189|mint:fj-10-1170.r2 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8625961|mint:MINT-8152151 - - psi-mi:"MI:0840"(stimulator) psi-mi:"MI:0503"(self) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0503"(self) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037501.2|refseq:NP_787063.1|ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|mint:Q9UJW3|rcsb pdb:2PV0|rcsb pdb:2PVC|rcsb pdb:2QRV|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:6U90|rcsb pdb:6U91|rcsb pdb:6W8B|rcsb pdb:6W89|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-5334118|dip:DIP-35238N|mint:MINT-8152166(identity) go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0046872"(metal ion binding)|go:"GO:0051719"("DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates")|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:O88508|rcsb pdb:3SW9|rcsb pdb:3SWC|reactome:R-MMU-212300|reactome:R-MMU-3214858|ensembl:ENSMUSG00000020661(gene)|ensembl:ENSMUST00000020991(transcript)|ensembl:ENSMUST00000174817(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_031898.1|refseq:NP_714965.1|refseq:XP_006515016.1|refseq:XP_006515019.1|refseq:NP_001258682.1|dip:DIP-38005N|mint:MINT-8152153(identity) - - - figure legend:f4|comment:homomint|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/04/04 2014/10/16 rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606 rogid:ZLqyo0sbBdWAlvbJ25rm+p58o5810090 intact-crc:7B91BBC491A81346|rigid:tonGAvHpOjKA3HhH2pQ9YQ7Vzts false his tag:?-?(MINT-8152167) his tag:?-?(MINT-8152161)|binding-associated region:608-908(MINT-8152158) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)