#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53197 uniprotkb:Q08981 intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:"MI:0096"(pull down) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8623634|mint:MINT-8185906|imex:IM-15425-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8185908(identity) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8185909(identity) - crc64:DA6DE5545607906B - comment:mint|figure legend:sf1 sf8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/07 2014/10/16 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 intact-crc:061ED44CA542A80D|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false his tag:?-?(MINT-8185911) maltose binding protein tag:?-?(MINT-8186887)|binding-associated region:58-128(MINT-8185919) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53197 uniprotkb:Q08981 intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:"MI:0096"(pull down) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8623654|mint:MINT-8186026|imex:IM-15425-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186028(identity) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186032(identity) - crc64:DA6DE5545607906B - comment:mint|figure legend:f1c f2d sf3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/07 2014/10/16 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 intact-crc:BDE0CF3B8739E37E|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false his tag:?-?(MINT-8186029) mutation disrupting interaction:65-65(MINT-8186054)|mutation disrupting interaction:119-119(MINT-8186048)|mutation disrupting interaction:98-98(MINT-8186040)|binding-associated region:1-128(MINT-8186033)|mutation disrupting interaction:99-99(MINT-8186043)|mutation disrupting interaction:122-122(MINT-8186051)|mutation disrupting interaction:100-100(MINT-8186046)|maltose binding protein tag:?-?(MINT-8186038)|mutation disrupting interaction:66-66(MINT-8186057) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53197 uniprotkb:P34244 intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C intact:EBI-9771|uniprotkb:A2NP40|ensemblfungi:YKL101W|uniprotkb:D6VXI6 psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:hsl1_yeast(display_long)|uniprotkb:YKL453(orf name)|uniprotkb:YKL101W(locus name)|uniprotkb:HSL1(gene name)|psi-mi:HSL1(display_short) psi-mi:"MI:0018"(two hybrid) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623711|mint:MINT-8185942|imex:IM-15425-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8185944(identity) refseq:NP_012821.2|sgd:S000001584|ensemblfungi:YKL101W(gene)|ensemblfungi:YKL101W_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902935"(protein localization to septin ring)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5L9T|rcsb pdb:5L9U|go:"GO:0000144"(cellular bud neck septin ring)|dip:DIP-3022N|mint:P34244|mint:MINT-8185951(identity) - crc64:DA6DE5545607906B crc64:803F84F7574304CD figure legend:sf2|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 rogid:9lnAFjeIZjowGo5Vxj/3sb/bLys559292 intact-crc:6FB9BEAD86FD2E29|rigid:DqAgP3LpWtiQMx+GIGWDasxhy+U false binding-associated region:201-566(MINT-8185947)|fusion protein:?-?(MINT-8185945) mutation disrupting interaction:777-777(MINT-8185964)|mutation disrupting interaction:776-776(MINT-8185961)|fusion protein:?-?(MINT-8185952)|binding-associated region:667-872(MINT-8185954)|mutation disrupting interaction:781-781(MINT-8185967)|mutation disrupting interaction:775-775(MINT-8185958) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53197 uniprotkb:Q08981 intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:"MI:0018"(two hybrid) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623793|mint:MINT-8186062|imex:IM-15425-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186064(identity) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186068(identity) - crc64:DA6DE5545607906B - figure legend:f2b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 intact-crc:8B196278A955574C|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false fusion protein:?-?(MINT-8186065)|binding-associated region:201-566(MINT-8186091) mutation disrupting interaction:99-99(MINT-8186079)|mutation disrupting interaction:66-66(MINT-8186069)|binding-associated region:1-128(MINT-8186085)|mutation disrupting interaction:119-119(MINT-8186075)|mutation disrupting interaction:122-122(MINT-8186073)|mutation disrupting interaction:98-98(MINT-8186081)|fusion protein:?-?(MINT-8186083)|mutation disrupting interaction:100-100(MINT-8186077)|mutation disrupting interaction:65-65(MINT-8186071) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08981 uniprotkb:P53197 intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:"MI:0018"(two hybrid) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623752|mint:MINT-8185995|imex:IM-15425-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186004(identity) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8185997(identity) - - crc64:DA6DE5545607906B comment:domino|comment:mint|figure legend:f1b sf2 sf8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 intact-crc:5C70475DEF8DCD8A|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false binding-associated region:1-128(MINT-8186007)|mutation disrupting interaction:66-66(MINT-8186016)|fusion protein:?-?(MINT-8186005)|mutation disrupting interaction:69-69(MINT-8186022)|mutation disrupting interaction:67-67(MINT-8186019)|mutation disrupting interaction:65-65(MINT-8186013) fusion protein:?-?(MINT-8185998)|binding-associated region:201-566(MINT-8186000) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08981 uniprotkb:P53197 intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:"MI:0018"(two hybrid) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623845|mint:MINT-8186121|imex:IM-15425-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186130(identity) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186123(identity) - - crc64:DA6DE5545607906B figure legend:f3a|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 intact-crc:7387A69C94372DEF|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false fusion protein:?-?(MINT-8186141)|mutation disrupting interaction:69-69(MINT-8186131)|mutation disrupting interaction:67-67(MINT-8186133)|mutation disrupting interaction:66-66(MINT-8186135)|mutation disrupting interaction:65-65(MINT-8186137) fusion protein:?-?(MINT-8186127)|mutation disrupting interaction:255-255(MINT-8186147)|mutation disrupting interaction:535-535(MINT-8186153)|mutation increasing interaction:536-536(MINT-8186156)|mutation disrupting interaction:258-258(MINT-8186150)|binding-associated region:201-566(MINT-8186124) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53197 uniprotkb:P34244 intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C intact:EBI-9771|uniprotkb:A2NP40|ensemblfungi:YKL101W|uniprotkb:D6VXI6 psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:hsl1_yeast(display_long)|uniprotkb:YKL453(orf name)|uniprotkb:YKL101W(locus name)|uniprotkb:HSL1(gene name)|psi-mi:HSL1(display_short) psi-mi:"MI:0018"(two hybrid) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623899|mint:MINT-8186160|imex:IM-15425-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186162(identity) refseq:NP_012821.2|sgd:S000001584|ensemblfungi:YKL101W(gene)|ensemblfungi:YKL101W_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902935"(protein localization to septin ring)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5G04|rcsb pdb:5KHR|rcsb pdb:5L9T|rcsb pdb:5L9U|go:"GO:0000144"(cellular bud neck septin ring)|dip:DIP-3022N|mint:P34244|mint:MINT-8186177(identity) - crc64:DA6DE5545607906B crc64:803F84F7574304CD figure legend:f3a|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 rogid:9lnAFjeIZjowGo5Vxj/3sb/bLys559292 intact-crc:C0A4C69AB9AB20B4|rigid:DqAgP3LpWtiQMx+GIGWDasxhy+U false fusion protein:?-?(MINT-8186171)|mutation disrupting interaction:258-258(MINT-8186167)|mutation disrupting interaction:535-535(MINT-8186165)|binding-associated region:201-566(MINT-8186173)|mutation disrupting interaction:255-255(MINT-8186169)|mutation increasing interaction:536-536(MINT-8186163) binding-associated region:667-872(MINT-8186190)|fusion protein:?-?(MINT-8186178) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08981 uniprotkb:P53197 intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623949|mint:MINT-8186193|imex:IM-15425-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186201(identity) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186195(identity) - - crc64:DA6DE5545607906B comment:mint|figure legend:sf7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 intact-crc:B0490FC0FFA0131F|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false mutation disrupting interaction:99-99(MINT-8186208)|mutation disrupting interaction:8-8(MINT-8186218)|ha tag:?-?(MINT-8186202)|mutation disrupting interaction:122-122(MINT-8186214)|mutation disrupting interaction:98-98(MINT-8186206)|mutation disrupting interaction:11-11(MINT-8186216)|mutation disrupting interaction:100-100(MINT-8186210)|mutation disrupting interaction:119-119(MINT-8186212) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q08981 uniprotkb:P53197 intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8624025|mint:MINT-8186251|imex:IM-15425-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186255(identity) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186253(identity) - - crc64:DA6DE5545607906B comment:mint|figure legend:sf7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 intact-crc:64F21EE94924104F|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false ha tag:?-?(MINT-8186266)|mutation decreasing interaction:67-67(MINT-8186264)|mutation decreasing interaction:65-65(MINT-8186260)|mutation decreasing interaction:69-69(MINT-8186258)|mutation decreasing interaction:66-66(MINT-8186262) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53197 uniprotkb:Q08981 intact:EBI-23684|uniprotkb:D6VUD5|ensemblfungi:YGL003C intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W psi-mi:cdh1_yeast(display_long)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:HCT1(gene name synonym)|uniprotkb:CDC20 homolog 1(gene name synonym)|uniprotkb:Homolog of CDC twenty 1(gene name synonym)|uniprotkb:YGL003C(locus name) psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Burton et al. (2011) mint:MINT-8185894|pubmed:21460798|imex:IM-15425|doi:10.1038/emboj.2011.90 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8623991|mint:MINT-8186227|imex:IM-15425-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011512.1|sgd:S000002971|dip:DIP-5915N|mint:P53197|ensemblfungi:YGL003C(gene)|ensemblfungi:YGL003C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0120151"(positive regulation of mitotic actomyosin contractile ring disassembly)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4BH6|rcsb pdb:5A31|reactome:R-SCE-174113|reactome:R-SCE-176407|reactome:R-SCE-69656|reactome:R-SCE-983168|mint:MINT-8186229(identity) sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|mint:MINT-8186231(identity) - crc64:DA6DE5545607906B - comment:mint|figure legend:sf7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/06/07 2014/10/16 rogid:1IBTs0ZBt6AM0LKb+LuyjLtA+PE559292 rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292 intact-crc:B669DEC682252447|rigid:/+1MbLmP6E2fqqUx7oUCUG48sRg false - mutation disrupting interaction:98-98(MINT-8186246)|mutation disrupting interaction:100-100(MINT-8186242)|mutation disrupting interaction:99-99(MINT-8186244)|mutation disrupting interaction:119-119(MINT-8186240)|mutation disrupting interaction:122-122(MINT-8186238)|ha tag:?-?(MINT-8186232) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)