#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:16618"	uniprotkb:Q8NDX1	intact:EBI-1257125	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate(display_short)|psi-mi:"CHEBI:16618"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990595|imex:IM-15739-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:B2CBE4901AAEFC76	false	-	sufficient binding region:776-892(IPR001849)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:11289"	uniprotkb:Q8NDX1	intact:EBI-3990582	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:1-phosphatidyl-1d-myo-inositol 4-phosphate(display_short)|psi-mi:"CHEBI:11289"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990586|imex:IM-15739-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:ED620D3E4AAE9B1D	false	-	sufficient binding region:776-892(IPR001849)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16500"	uniprotkb:Q8NDX1	intact:EBI-1257117	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:pi5p(display_short)|psi-mi:"CHEBI:16500"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990565|imex:IM-15739-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:53331F001AADDD6F	false	-	sufficient binding region:776-892(IPR001849)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16152"	uniprotkb:Q8NDX1	intact:EBI-2296297	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:1-phosphatidyl-1d-myo-inositol 3,4-bisphosphate(display_short)|psi-mi:"CHEBI:16152"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990517|imex:IM-15739-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:30B24AC01AAD14C5	false	-	glutathione s tranferase tag:?-?|sufficient binding region:776-892(IPR001849)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:18348"	uniprotkb:Q8NDX1	intact:EBI-1257123	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate(display_short)|psi-mi:"CHEBI:18348"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990536|imex:IM-15739-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:EC7830FCBAAEFD83	false	-	sufficient binding region:776-892(IPR001849)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16851"	uniprotkb:Q8NDX1	intact:EBI-1257121	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate(display_short)|psi-mi:"CHEBI:16851"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990527|imex:IM-15739-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:D026F8301AADB8B6	false	-	glutathione s tranferase tag:?-?|sufficient binding region:776-892(IPR001849)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16337"	uniprotkb:Q8NDX1	intact:EBI-1263288	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:phosphatidic acids(display_short)|psi-mi:"CHEBI:16337"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990545|imex:IM-15739-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:26EB98201AACE10C	false	-	sufficient binding region:776-892(IPR001849)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:17283"	uniprotkb:Q8NDX1	intact:EBI-1257113	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990554|imex:IM-15739-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	-	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:B5C80E296AAD723F	false	-	glutathione s tranferase tag:?-?|sufficient binding region:776-892(IPR001849)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N8R7	uniprotkb:Q8N4G2	intact:EBI-2807994|ensembl:ENSP00000282032|uniprotkb:Q5HYH9	intact:EBI-3921493|uniprotkb:Q9H655|ensembl:ENSP00000323847	psi-mi:al14e_human(display_long)|uniprotkb:ARL14EP(gene name)|psi-mi:ARL14EP(display_short)|uniprotkb:ARF7 effector protein(gene name synonym)|uniprotkb:ARF7EP(gene name synonym)|uniprotkb:C11orf46(gene name synonym)	psi-mi:arl14_human(display_long)|uniprotkb:ARL14(gene name)|psi-mi:ARL14(display_short)|uniprotkb:ARF7(gene name synonym)|uniprotkb:ADP-ribosylation factor 7(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4279451|imex:IM-15739-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152219(gene)|ensembl:ENST00000282032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026515|interpro:IPR029264|refseq:NP_689529.1	refseq:NP_079323.1|ensembl:ENSG00000179674(gene)|ensembl:ENST00000320767(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 7F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mel_juso)|taxid:9606(Homo sapiens)	-	2011/06/14	2014/10/16	rogid:i4NYCAjZ8uvzr0oZqlIbnaOq7n49606	rogid:7Fi1v32EgjFh3EcGN46Tb16wF9Q9606	intact-crc:E066FFEAF8CF3425|rigid:oqjibVZ90e4Vf5wEsHwwKbWFWpA	false	ha tag:?-?	sufficient binding region:3-192|red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8N4G2	uniprotkb:Q99755	intact:EBI-3921493|uniprotkb:Q9H655|ensembl:ENSP00000323847	intact:EBI-726414|uniprotkb:Q99754|uniprotkb:Q99756|uniprotkb:B4DIN0|uniprotkb:A8K4Q0|ensembl:ENSP00000357883	psi-mi:arl14_human(display_long)|uniprotkb:ARL14(gene name)|psi-mi:ARL14(display_short)|uniprotkb:ARF7(gene name synonym)|uniprotkb:ADP-ribosylation factor 7(gene name synonym)	psi-mi:pi51a_human(display_long)|uniprotkb:PIP5K1A(gene name)|psi-mi:PIP5K1A(display_short)|uniprotkb:68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I alpha(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4279677|imex:IM-15739-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079323.1|ensembl:ENSG00000179674(gene)|ensembl:ENST00000320767(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417	refseq:NP_001129108.1|refseq:NP_001129109.1|refseq:NP_001129110.1|refseq:NP_003548.1|refseq:NP_001317618.1|ensembl:ENSG00000143398(gene)|ensembl:ENST00000368888(transcript)|go:"GO:0000285"(1-phosphatidylinositol-3-phosphate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0052810"(1-phosphatidylinositol-5-kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097178"(ruffle assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|reactome:R-HSA-1660499|reactome:R-HSA-6811558|dip:DIP-60649N	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 7F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mel_juso)|taxid:9606(Homo sapiens)	-	2011/06/14	2014/10/16	rogid:7Fi1v32EgjFh3EcGN46Tb16wF9Q9606	rogid:jDE/jXrUlbohCr2mZjEgIxTVzjU9606	intact-crc:C2BB356691E50C37|rigid:v+tkyXrudrSHcXIcbvG/UPtFlJQ	false	red fluorescent protein tag:?-?|sufficient binding region:3-192	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8N8R7	uniprotkb:Q12965	intact:EBI-2807994|ensembl:ENSP00000282032|uniprotkb:Q5HYH9	intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235	psi-mi:al14e_human(display_long)|uniprotkb:ARL14EP(gene name)|psi-mi:ARL14EP(display_short)|uniprotkb:ARF7 effector protein(gene name synonym)|uniprotkb:ARF7EP(gene name synonym)|uniprotkb:C11orf46(gene name synonym)	psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4279573|imex:IM-15739-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152219(gene)|ensembl:ENST00000282032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026515|interpro:IPR029264|refseq:NP_689529.1	refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 7I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-pbmc)|taxid:9606(Human Peripheral Blood Mononuclear cell)	-	2011/06/14	2014/10/16	rogid:i4NYCAjZ8uvzr0oZqlIbnaOq7n49606	rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606	intact-crc:918C56CC8B0E97DE|rigid:gpRlfS9PG/KrSss7Vkmp+XIpJ2A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12965	uniprotkb:Q8N8R7	intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235	intact:EBI-2807994|ensembl:ENSP00000282032|uniprotkb:Q5HYH9	psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym)	psi-mi:al14e_human(display_long)|uniprotkb:ARL14EP(gene name)|psi-mi:ARL14EP(display_short)|uniprotkb:ARF7 effector protein(gene name synonym)|uniprotkb:ARF7EP(gene name synonym)|uniprotkb:C11orf46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4279538|imex:IM-15739-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N	ensembl:ENSG00000152219(gene)|ensembl:ENST00000282032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026515|interpro:IPR029264|refseq:NP_689529.1	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 7E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606	rogid:i4NYCAjZ8uvzr0oZqlIbnaOq7n49606	intact-crc:D426ECE92EF15337|rigid:gpRlfS9PG/KrSss7Vkmp+XIpJ2A	false	green fluorescent protein tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8N4G2	uniprotkb:Q8N8R7	intact:EBI-3921493|uniprotkb:Q9H655|ensembl:ENSP00000323847	intact:EBI-2807994|ensembl:ENSP00000282032|uniprotkb:Q5HYH9	psi-mi:arl14_human(display_long)|uniprotkb:ARL14(gene name)|psi-mi:ARL14(display_short)|uniprotkb:ARF7(gene name synonym)|uniprotkb:ADP-ribosylation factor 7(gene name synonym)	psi-mi:al14e_human(display_long)|uniprotkb:ARL14EP(gene name)|psi-mi:ARL14EP(display_short)|uniprotkb:ARF7 effector protein(gene name synonym)|uniprotkb:ARF7EP(gene name synonym)|uniprotkb:C11orf46(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4279596|imex:IM-15739-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079323.1|ensembl:ENSG00000179674(gene)|ensembl:ENST00000320767(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417	ensembl:ENSG00000152219(gene)|ensembl:ENST00000282032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026515|interpro:IPR029264|refseq:NP_689529.1	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/06/14	2014/10/16	rogid:7Fi1v32EgjFh3EcGN46Tb16wF9Q9606	rogid:i4NYCAjZ8uvzr0oZqlIbnaOq7n49606	intact-crc:073080114E1F6828|rigid:oqjibVZ90e4Vf5wEsHwwKbWFWpA	false	sufficient binding region:3-192	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N4G2	uniprotkb:Q8NDX1	intact:EBI-3921493|uniprotkb:Q9H655|ensembl:ENSP00000323847	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	psi-mi:arl14_human(display_long)|uniprotkb:ARL14(gene name)|psi-mi:ARL14(display_short)|uniprotkb:ARF7(gene name synonym)|uniprotkb:ADP-ribosylation factor 7(gene name synonym)	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990490|imex:IM-15739-6	-	-	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079323.1|ensembl:ENSG00000179674(gene)|ensembl:ENST00000320767(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	rogid:7Fi1v32EgjFh3EcGN46Tb16wF9Q9606	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:D5B7888AE22E1A39|rigid:pznvd/VPbaTFD+7tW4mQqBplOVM	false	glutathione s tranferase tag:?-?	sufficient binding region:555-738(IPR000904)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NDX1	uniprotkb:P62330	intact:EBI-2211897|uniprotkb:A8K1Y0|uniprotkb:A6NEG7|uniprotkb:O95621|uniprotkb:Q4ZG34|uniprotkb:Q6GPH8|uniprotkb:Q8IYP4|intact:EBI-28967881|ensembl:ENSP00000245796	intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2	psi-mi:psd4_human(display_long)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3990500|imex:IM-15739-7	-	-	psi-mi:"MI:0918"(donor)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000245796|ensembl:ENST00000441564|ensembl:ENSP00000413997|refseq:NP_036587.2|refseq:XP_005263691.1|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016020"(membrane)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032587"(ruffle membrane)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681	refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/14	2014/10/16	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	intact-crc:07D296733924D0B7|rigid:WEdHgQxwtVWCaSTU8xICdDkB+ps	false	sufficient binding region:555-738(IPR000904)	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N4G2	uniprotkb:Q8N8R7	intact:EBI-3921493|uniprotkb:Q9H655|ensembl:ENSP00000323847	intact:EBI-2807994|ensembl:ENSP00000282032|uniprotkb:Q5HYH9	psi-mi:arl14_human(display_long)|uniprotkb:ARL14(gene name)|psi-mi:ARL14(display_short)|uniprotkb:ARF7(gene name synonym)|uniprotkb:ADP-ribosylation factor 7(gene name synonym)	psi-mi:al14e_human(display_long)|uniprotkb:ARL14EP(gene name)|psi-mi:ARL14EP(display_short)|uniprotkb:ARF7 effector protein(gene name synonym)|uniprotkb:ARF7EP(gene name synonym)|uniprotkb:C11orf46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Paul et al. (2011)	imex:IM-15739|pubmed:21458045	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4279435|imex:IM-15739-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079323.1|ensembl:ENSG00000179674(gene)|ensembl:ENST00000320767(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417	ensembl:ENSG00000152219(gene)|ensembl:ENST00000282032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026515|interpro:IPR029264|refseq:NP_689529.1	psi-mi:"MI:0469"(intact)|psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 7E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mel_juso)|taxid:9606(Homo sapiens)	-	2011/06/14	2014/10/16	rogid:7Fi1v32EgjFh3EcGN46Tb16wF9Q9606	rogid:i4NYCAjZ8uvzr0oZqlIbnaOq7n49606	intact-crc:0C06B73E18A52E26|rigid:oqjibVZ90e4Vf5wEsHwwKbWFWpA	false	sufficient binding region:3-192|red fluorescent protein tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)