#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P40758	uniprotkb:Q45666	intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym)	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617499|mint:MINT-8145104|imex:IM-16704-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8145106(identity)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145108(identity)	-	comment:mint	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	figure legend:f1b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	-	2011/03/15	2014/10/16	rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	intact-crc:C78A9E513E14C15D|rigid:gwcZtlxdDsLMD+QzarHhXzrR3xY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q45666	uniprotkb:P40758	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617475|mint:MINT-8145083|imex:IM-16704-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145086(identity)	refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8145085(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	comment:mint	figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308	intact-crc:86A30CD7C1BF1149|rigid:gwcZtlxdDsLMD+QzarHhXzrR3xY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q45666	uniprotkb:P12425	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-6402863|ensemblbacteria:CAB13630	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617487|mint:MINT-8145094|imex:IM-16704-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145096(identity)	ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8145097(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	crc64:83A5657CE1388AB0	figure legend:f1a|comment:mint|comment:In the TnrA-immunoprecipitate of GlnK-deficient cells,GS was co-purified with TnrA and the recovery of GS was independent on whether the cells were nitrate-grown or shifted to nitrate-deprived medium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308	intact-crc:3E4D24AEA491A316|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q45666	uniprotkb:P12425	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-6402863|ensemblbacteria:CAB13630	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617511|mint:MINT-8145115|imex:IM-16704-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145117(identity)	ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8145119(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	crc64:83A5657CE1388AB0	figure legend:f1c|comment:mint|comment:"TnrA was co-purified with immunoprecipitated GlnK   was recovered by GS  immunoprecipitation only in the GlnK-deficient mutant (Fig. 1C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308	intact-crc:9B2865ED944C76DB|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q45666	uniprotkb:P40758	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617532|mint:MINT-8145129|imex:IM-16704-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145131(identity)	refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8145132(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	comment:mint	comment:mint|figure legend:f2 f3 f6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308	intact-crc:5155B80A5A622687|rigid:gwcZtlxdDsLMD+QzarHhXzrR3xY	false	binding-associated region:75-90(MINT-8145175)|his tag:?-?(MINT-8145137)	tag:?-?(MINT-8145141)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q45666	uniprotkb:P12425	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-6402863|ensemblbacteria:CAB13630	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617553|mint:MINT-8145149|imex:IM-16704-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145151(identity)	ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8145152(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	crc64:83A5657CE1388AB0	comment:mint|figure legend:f5 f6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308	intact-crc:0593541BCCE05087|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88	false	his tag:?-?(MINT-8145154)|binding-associated region:104-110(MINT-8145167)	tag:?-?(MINT-8145158)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q45666	uniprotkb:P12425	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-6402863|ensemblbacteria:CAB13630	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)	psi-mi:"MI:0096"(pull down)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617603|mint:MINT-8145196|imex:IM-16704-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145198(identity)	ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8145204(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	crc64:83A5657CE1388AB0	figure legend:f6b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308	intact-crc:C6BAFF2C1EC6AACB|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88	false	his tag:?-?(MINT-8145201)|binding-associated region:104-110(MINT-8145199)	tag:?-?(MINT-8145205)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q45666	uniprotkb:P12425	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-6402863|ensemblbacteria:CAB13630	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)	psi-mi:"MI:0096"(pull down)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617583|mint:MINT-8145181|imex:IM-16704-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145183(identity)	ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8145184(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	crc64:83A5657CE1388AB0	figure legend:f6b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308	intact-crc:99FCEB9A6AF53E4B|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88	false	binding-associated region:104-110(MINT-8145188)|his tag:?-?(MINT-8145185)	tag:?-?(MINT-8145191)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40758	uniprotkb:Q45666	intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym)	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617643|mint:MINT-8145226|imex:IM-16704-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8145234(identity)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145228(identity)	-	comment:mint	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	figure legend:f6c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	intact-crc:0DA70E1D7A34C668|rigid:gwcZtlxdDsLMD+QzarHhXzrR3xY	false	tag:?-?(MINT-8145235)	binding-associated region:75-90(MINT-8145229)|his tag:?-?(MINT-8145231)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40758	uniprotkb:Q45666	intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym)	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617623|mint:MINT-8145211|imex:IM-16704-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8145214(identity)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145213(identity)	-	comment:mint	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA	figure legend:f6c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	intact-crc:5499616B6C7E4444|rigid:gwcZtlxdDsLMD+QzarHhXzrR3xY	false	tag:?-?(MINT-8145222)	binding-associated region:75-90(MINT-8145219)|his tag:?-?(MINT-8145216)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q45666	uniprotkb:Q45666	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Kayumov et al. (2011)	mint:MINT-8145059|pubmed:21435182|imex:IM-16704|mint:fj-11-0067.r1	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	taxid:224308(bacsu)|taxid:224308(Bacillus subtilis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617672|mint:MINT-8145247|imex:IM-16704-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145249(identity)	refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8145249(identity)	-	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA|comment:"Stoichiometry: 2.0"	comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA|comment:"Stoichiometry: 2.0"	figure legend:sf3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/15	2014/10/16	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	rogid:3loDv98VplHW96s2wkpgsgj0CE8224308	intact-crc:A912762A2F6CD057|rigid:Wd8WEJ/+7kGj7SsHiMrY0q3ZSvo	false	-	-	2	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)