#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13586	uniprotkb:Q13586	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Muik et al. (2011)	mint:MINT-8186898|pubmed:21427704|imex:IM-15424|doi:10.1038/emboj.2011.79	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617095|mint:MINT-8186906|imex:IM-15424-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N|mint:MINT-8186908(identity)	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N|mint:MINT-8186908(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f4c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/06/10	2014/10/16	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:48D8B456495D6D7B|rigid:184IV+takMKeSfTZ+SGdNeeWiPQ	false	binding-associated region:234-491(MINT-8186911)	binding-associated region:234-491(MINT-8186911)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13586	uniprotkb:Q96D31	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Muik et al. (2011)	mint:MINT-8186898|pubmed:21427704|imex:IM-15424|doi:10.1038/emboj.2011.79	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617116|mint:MINT-8186918|imex:IM-15424-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N|mint:MINT-8186920(identity)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N|mint:MINT-8186925(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f6 sf6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/06/10	2014/10/16	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	intact-crc:791D9B9CEE895482|rigid:vcTi++PINtFYRSz2u8Diz54La3s	false	binding-associated region:199-535(MINT-8187612)	cyan fluorescent protein tag:?-?(MINT-8186926)	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q13586	uniprotkb:Q13586	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Muik et al. (2011)	mint:MINT-8186898|pubmed:21427704|imex:IM-15424|doi:10.1038/emboj.2011.79	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617142|mint:MINT-8186937|imex:IM-15424-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N|mint:MINT-8186939(identity)	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N|mint:MINT-8186943(identity)	-	-	-	figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/06/10	2014/10/16	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:C737BD08FA80CFC2|rigid:L1wBeQgGonyuASFyhXKpOEAJUb0	false	binding-associated region:233-491(MINT-8186955)|yellow fluorescent protein tag:?-?(MINT-8186940)	binding-associated region:233-491(MINT-8186961)|cyan fluorescent protein tag:?-?(MINT-8186958)	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)