#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y376 uniprotkb:O95747 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-620853|intact:EBI-28983016|ensembl:ENSP00000311713|uniprotkb:Q3LR53|uniprotkb:Q7Z501|uniprotkb:Q9UPQ1|intact:EBI-21354189 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:oxsr1_human(display_long)|uniprotkb:Oxidative stress-responsive 1 protein(gene name synonym)|uniprotkb:OXSR1(gene name)|psi-mi:OXSR1(display_short)|uniprotkb:OSR1(gene name synonym)|uniprotkb:KIAA1101(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615257|mint:MINT-8186566|imex:IM-15875-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186571(identity) ensembl:ENSG00000172939(gene)|ensembl:ENST00000311806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|interpro:IPR028749|mint:O95747|rcsb pdb:2V3S|rcsb pdb:2VWI|rcsb pdb:3DAK|ensembl:ENSP00000311713|refseq:NP_005100.1|dip:DIP-34977N|mint:MINT-8186569(identity) - - - comment:homomint|comment:mint|figure legend:f3b f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.7x10^-6(molar) 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:B/vq09Ygsvo5paZdMXlX9tyo7aE9606 intact-crc:AC5D9EBAD264914E|rigid:e53tqBKkwTF+tAjPi0i5/Ud+gdc false mutation disrupting interaction:260-260(MINT-8186654)|mutation disrupting interaction:227-227(MINT-8186652) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y376 uniprotkb:Q9UEW8 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-2680974|uniprotkb:Q9UER4|uniprotkb:O14774|uniprotkb:Q53S90|uniprotkb:Q53SL7|uniprotkb:Q53SS1|ensembl:ENSP00000348278|uniprotkb:X5D9C8 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk39_human(display_long)|uniprotkb:SPAK(gene name synonym)|uniprotkb:DCHT(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:STK39(gene name)|psi-mi:STK39(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615236|mint:MINT-8186556|imex:IM-15875-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186559(identity) refseq:NP_037365.2|ensembl:ENSG00000198648(gene)|ensembl:ENST00000355999(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|mint:MINT-8186558(identity) - - - comment:homomint|comment:mint|figure legend:f3a f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:8.2x10^-6(molar) 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:472OT0D4ddZoxjICU4UOhTOJ4Oo9606 intact-crc:2C591CB56D7CB07C|rigid:zwuo4qxE8rdayUb8fRAzOkvpT40 false mutation disrupting interaction:260-260(MINT-8186623)|mutation disrupting interaction:227-227(MINT-8186621) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P289 uniprotkb:Q9Y376 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615299|mint:MINT-8186588|imex:IM-15875-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N|mint:MINT-8186593(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186591(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.03x10^-6(molar) 2011/06/09 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:E5BAB47752BB3259|rigid:6U96KAi5X1kAChyM1iSWVK0XXiU false - mutation decreasing interaction:227-227(MINT-8186596) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P289 uniprotkb:Q9Y376 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615278|mint:MINT-8186577|imex:IM-15875-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N|mint:MINT-8186580(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186582(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.8x10^-6(molar) 2011/06/09 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:BE939B2F483B20AC|rigid:6U96KAi5X1kAChyM1iSWVK0XXiU false - mutation disrupting interaction:227-227(MINT-8186601)|mutation disrupting interaction:260-260(MINT-8186603) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y376 uniprotkb:Q9UEW8 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-2680974|uniprotkb:Q9UER4|uniprotkb:O14774|uniprotkb:Q53S90|uniprotkb:Q53SL7|uniprotkb:Q53SS1|ensembl:ENSP00000348278|uniprotkb:X5D9C8 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk39_human(display_long)|uniprotkb:SPAK(gene name synonym)|uniprotkb:DCHT(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:STK39(gene name)|psi-mi:STK39(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615333|mint:MINT-8186626|imex:IM-15875-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186631(identity) refseq:NP_037365.2|ensembl:ENSG00000198648(gene)|ensembl:ENST00000355999(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|mint:MINT-8186629(identity) - - - comment:homomint|comment:mint|figure legend:f3a f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.8x10^-5(molar) 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:472OT0D4ddZoxjICU4UOhTOJ4Oo9606 intact-crc:24CE9A73D2AC8879|rigid:zwuo4qxE8rdayUb8fRAzOkvpT40 false mutation decreasing interaction:227-227(MINT-8186634) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y376 uniprotkb:Q9P289 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615316|mint:MINT-8186607|imex:IM-15875-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186610(identity) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N|mint:MINT-8186616(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.45x10^-4(molar) 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:9163B343AB3FF3EC|rigid:6U96KAi5X1kAChyM1iSWVK0XXiU false mutation decreasing interaction:260-260(MINT-8186611) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UEW8 uniprotkb:Q9Y376 intact:EBI-2680974|uniprotkb:Q9UER4|uniprotkb:O14774|uniprotkb:Q53S90|uniprotkb:Q53SL7|uniprotkb:Q53SS1|ensembl:ENSP00000348278|uniprotkb:X5D9C8 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:stk39_human(display_long)|uniprotkb:SPAK(gene name synonym)|uniprotkb:DCHT(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:STK39(gene name)|psi-mi:STK39(display_short) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615350|mint:MINT-8186640|imex:IM-15875-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037365.2|ensembl:ENSG00000198648(gene)|ensembl:ENST00000355999(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|mint:MINT-8186643(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186645(identity) - - - comment:homomint|comment:mint|figure legend:f3a f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.16x10^-4(molar) 2011/06/09 2014/10/16 rogid:472OT0D4ddZoxjICU4UOhTOJ4Oo9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:912B11878E7D5F5C|rigid:zwuo4qxE8rdayUb8fRAzOkvpT40 false - mutation decreasing interaction:260-260(MINT-8186646) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95747 uniprotkb:Q9Y376 intact:EBI-620853|intact:EBI-28983016|ensembl:ENSP00000311713|uniprotkb:Q3LR53|uniprotkb:Q7Z501|uniprotkb:Q9UPQ1|intact:EBI-21354189 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:oxsr1_human(display_long)|uniprotkb:Oxidative stress-responsive 1 protein(gene name synonym)|uniprotkb:OXSR1(gene name)|psi-mi:OXSR1(display_short)|uniprotkb:OSR1(gene name synonym)|uniprotkb:KIAA1101(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615373|mint:MINT-8186657|imex:IM-15875-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172939(gene)|ensembl:ENST00000311806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|interpro:IPR028749|mint:O95747|rcsb pdb:2V3S|rcsb pdb:2VWI|rcsb pdb:3DAK|ensembl:ENSP00000311713|refseq:NP_005100.1|dip:DIP-34977N|mint:MINT-8186666(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186660(identity) - - - comment:homomint|comment:mint|figure legend:f3b f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.16x10^-4(molar) 2011/06/09 2014/10/16 rogid:B/vq09Ygsvo5paZdMXlX9tyo7aE9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:44165555C0F20676|rigid:e53tqBKkwTF+tAjPi0i5/Ud+gdc false - mutation decreasing interaction:227-227(MINT-8186663) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y376 uniprotkb:O95747 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-620853|intact:EBI-28983016|ensembl:ENSP00000311713|uniprotkb:Q3LR53|uniprotkb:Q7Z501|uniprotkb:Q9UPQ1|intact:EBI-21354189 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:oxsr1_human(display_long)|uniprotkb:Oxidative stress-responsive 1 protein(gene name synonym)|uniprotkb:OXSR1(gene name)|psi-mi:OXSR1(display_short)|uniprotkb:OSR1(gene name synonym)|uniprotkb:KIAA1101(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8615438|mint:MINT-8186672|imex:IM-15875-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186675(identity) ensembl:ENSG00000172939(gene)|ensembl:ENST00000311806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|interpro:IPR028749|mint:O95747|rcsb pdb:2V3S|rcsb pdb:2VWI|rcsb pdb:3DAK|ensembl:ENSP00000311713|refseq:NP_005100.1|dip:DIP-34977N|mint:MINT-8186679(identity) - - - comment:homomint|comment:mint|figure legend:f3b f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.65x10^-4(molar) 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:B/vq09Ygsvo5paZdMXlX9tyo7aE9606 intact-crc:F1F3DEA19C23D153|rigid:e53tqBKkwTF+tAjPi0i5/Ud+gdc false mutation decreasing interaction:260-260(MINT-8186676) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UEW8 uniprotkb:Q9Y376 intact:EBI-2680974|uniprotkb:Q9UER4|uniprotkb:O14774|uniprotkb:Q53S90|uniprotkb:Q53SL7|uniprotkb:Q53SS1|ensembl:ENSP00000348278|uniprotkb:X5D9C8 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:stk39_human(display_long)|uniprotkb:SPAK(gene name synonym)|uniprotkb:DCHT(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:STK39(gene name)|psi-mi:STK39(display_short) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615507|mint:MINT-8186728|imex:IM-15875-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037365.2|ensembl:ENSG00000198648(gene)|ensembl:ENST00000355999(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|mint:MINT-8186730(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186734(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:472OT0D4ddZoxjICU4UOhTOJ4Oo9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:5D02291B455F1277|rigid:zwuo4qxE8rdayUb8fRAzOkvpT40 false flag tag:?-?(MINT-8186731) myc tag:?-?(MINT-8186735) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7RTN6 uniprotkb:Q9Y376 intact:EBI-1109114|uniprotkb:Q5JPI2|uniprotkb:Q7Z4K9|uniprotkb:Q8NC31|uniprotkb:Q8NCF1|uniprotkb:Q9H272|ensembl:ENSP00000336655|uniprotkb:B4DDE3|uniprotkb:B4DW17|uniprotkb:J3KTC9 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:straa_human(display_long)|uniprotkb:STRADA(gene name)|psi-mi:STRADA(display_short)|uniprotkb:Serologically defined breast cancer antigen NY-BR-96(gene name synonym)|uniprotkb:STRAD(gene name synonym)|uniprotkb:LYK5(gene name synonym)|uniprotkb:STE20-related adapter protein(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615551|mint:MINT-8186758|imex:IM-15875-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003786.1|refseq:NP_001003787.1|refseq:NP_001003788.1|refseq:NP_001159441.1|refseq:NP_001159442.1|refseq:NP_699166.2|interpro:IPR011009(Protein kinase-like)|rcsb pdb:1UPK|rcsb pdb:2WTK|rcsb pdb:3GNI|reactome:R-HSA-380972|interpro:IPR000719(Protein kinase, core)|ensembl:ENSG00000266173(gene)|ensembl:ENST00000336174(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0019900"(kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|refseq:XP_005257856.1|dip:DIP-35775N|mint:MINT-8186768(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186760(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:WoEj2CkvNp1pV4Hx5asrQMddP5w9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:D240376C06DC31E2|rigid:2Q+4rQIvEyr92d0Ep81VeFhU1Ho false flag tag:?-?(MINT-8186769) mutation disrupting interaction:260-260(MINT-8186765)|myc tag:?-?(MINT-8186763) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7RTN6 uniprotkb:Q9Y376 intact:EBI-1109114|uniprotkb:Q5JPI2|uniprotkb:Q7Z4K9|uniprotkb:Q8NC31|uniprotkb:Q8NCF1|uniprotkb:Q9H272|ensembl:ENSP00000336655|uniprotkb:B4DDE3|uniprotkb:B4DW17|uniprotkb:J3KTC9 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:straa_human(display_long)|uniprotkb:STRADA(gene name)|psi-mi:STRADA(display_short)|uniprotkb:Serologically defined breast cancer antigen NY-BR-96(gene name synonym)|uniprotkb:STRAD(gene name synonym)|uniprotkb:LYK5(gene name synonym)|uniprotkb:STE20-related adapter protein(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615525|mint:MINT-8186742|imex:IM-15875-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003786.1|refseq:NP_001003787.1|refseq:NP_001003788.1|refseq:NP_001159441.1|refseq:NP_001159442.1|refseq:NP_699166.2|interpro:IPR011009(Protein kinase-like)|rcsb pdb:1UPK|rcsb pdb:2WTK|rcsb pdb:3GNI|reactome:R-HSA-380972|interpro:IPR000719(Protein kinase, core)|ensembl:ENSG00000266173(gene)|ensembl:ENST00000336174(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0019900"(kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|refseq:XP_005257856.1|dip:DIP-35775N|mint:MINT-8186744(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186748(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:WoEj2CkvNp1pV4Hx5asrQMddP5w9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:3C3EBA3FA8AF1FBE|rigid:2Q+4rQIvEyr92d0Ep81VeFhU1Ho false flag tag:?-?(MINT-8186745) mutation disrupting interaction:227-227(MINT-8186753)|myc tag:?-?(MINT-8186751)|mutation disrupting interaction:260-260(MINT-8186749) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y376 uniprotkb:Q9P289 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615595|mint:MINT-8186788|imex:IM-15875-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186794(identity) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N|mint:MINT-8186790(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:774E314404640A25|rigid:6U96KAi5X1kAChyM1iSWVK0XXiU false mutation disrupting interaction:227-227(MINT-8186799)|myc tag:?-?(MINT-8186797)|mutation disrupting interaction:260-260(MINT-8186795) flag tag:?-?(MINT-8186791) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y376 uniprotkb:Q7RTN6 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-1109114|uniprotkb:Q5JPI2|uniprotkb:Q7Z4K9|uniprotkb:Q8NC31|uniprotkb:Q8NCF1|uniprotkb:Q9H272|ensembl:ENSP00000336655|uniprotkb:B4DDE3|uniprotkb:B4DW17|uniprotkb:J3KTC9 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:straa_human(display_long)|uniprotkb:STRADA(gene name)|psi-mi:STRADA(display_short)|uniprotkb:Serologically defined breast cancer antigen NY-BR-96(gene name synonym)|uniprotkb:STRAD(gene name synonym)|uniprotkb:LYK5(gene name synonym)|uniprotkb:STE20-related adapter protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615573|mint:MINT-8186774|imex:IM-15875-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186776(identity) refseq:NP_001003786.1|refseq:NP_001003787.1|refseq:NP_001003788.1|refseq:NP_001159441.1|refseq:NP_001159442.1|refseq:NP_699166.2|interpro:IPR011009(Protein kinase-like)|rcsb pdb:1UPK|rcsb pdb:2WTK|rcsb pdb:3GNI|reactome:R-HSA-380972|interpro:IPR000719(Protein kinase, core)|ensembl:ENSG00000266173(gene)|ensembl:ENST00000336174(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0019900"(kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|refseq:XP_005257856.1|dip:DIP-35775N|mint:MINT-8186782(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:WoEj2CkvNp1pV4Hx5asrQMddP5w9606 intact-crc:8AC7A4696D224CB4|rigid:2Q+4rQIvEyr92d0Ep81VeFhU1Ho false mutation disrupting interaction:227-227(MINT-8186777)|myc tag:?-?(MINT-8186779) flag tag:?-?(MINT-8186783) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P289 uniprotkb:Q9Y376 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615678|mint:MINT-8186820|imex:IM-15875-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N|mint:MINT-8186828(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186822(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:AA93434CA4A21D17|rigid:6U96KAi5X1kAChyM1iSWVK0XXiU false flag tag:?-?(MINT-8186829) mutation disrupting interaction:260-260(MINT-8186825)|myc tag:?-?(MINT-8186823) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P289 uniprotkb:Q9Y376 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615656|mint:MINT-8186804|imex:IM-15875-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N|mint:MINT-8186814(identity) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186806(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 intact-crc:67DD0B578768345D|rigid:6U96KAi5X1kAChyM1iSWVK0XXiU false flag tag:?-?(MINT-8186815) myc tag:?-?(MINT-8186809)|mutation disrupting interaction:227-227(MINT-8186807) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y376 uniprotkb:O00506 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615726|mint:MINT-8186850|imex:IM-15875-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186852(identity) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N|mint:MINT-8186860(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:3AF1C5ECB3556327|rigid:wGzDG+dPAA8Gpr3hKfvC09ywoCY false mutation disrupting interaction:227-227(MINT-8186853)|myc tag:?-?(MINT-8186855) flag tag:?-?(MINT-8186861) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y376 uniprotkb:O00506 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615700|mint:MINT-8186834|imex:IM-15875-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186840(identity) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N|mint:MINT-8186836(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:365F64F92BB3366B|rigid:wGzDG+dPAA8Gpr3hKfvC09ywoCY false mutation disrupting interaction:260-260(MINT-8186841)|myc tag:?-?(MINT-8186843)|mutation disrupting interaction:227-227(MINT-8186845) flag tag:?-?(MINT-8186837) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y376 uniprotkb:O00506 intact:EBI-306905|ensembl:ENSP00000258418|ensembl:ENSP00000386238|ensembl:ENSP00000386642|uniprotkb:A8K8L7 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:cab39_human(display_long)|uniprotkb:CAB39(gene name)|psi-mi:CAB39(display_short)|uniprotkb:CGI-66(orf name)|uniprotkb:MO25alpha(gene name synonym)|uniprotkb:MO25(gene name synonym)|uniprotkb:Protein Mo25(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Filippi et al. (2011) mint:MINT-8186547|pubmed:21423148|imex:IM-15875|doi:10.1038/emboj.2011.78 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8615748|mint:MINT-8186866|imex:IM-15875-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|go:"GO:0014823"(response to activity)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1UPK|ensembl:ENSG00000135932(gene)|ensembl:ENST00000258418(transcript)|ensembl:ENST00000409788(transcript)|ensembl:ENST00000410084(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:2WTK|rcsb pdb:3GNI|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4NZW|rcsb pdb:4O27|reactome:R-HSA-380972|reactome:R-HSA-6798695|rcsb pdb:1UPL|refseq:NP_001124321.1|refseq:NP_001124322.1|refseq:NP_057373.1|dip:DIP-31316N|mint:MINT-8186868(identity) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N|mint:MINT-8186874(identity) - - - comment:homomint|comment:mint|figure legend:sf13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/06/09 2014/10/16 rogid:lexzsGjO9gx4s7ANiX7FrBpg5wc9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:627656E9D8AB1E71|rigid:wGzDG+dPAA8Gpr3hKfvC09ywoCY false mutation disrupting interaction:260-260(MINT-8186871)|myc tag:?-?(MINT-8186869) flag tag:?-?(MINT-8186875) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)