#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y696 uniprotkb:P52293 intact:EBI-1057480|uniprotkb:Q9UFW9|uniprotkb:Q9UQJ6|ensembl:ENSP00000363500|ensembl:ENSP00000436538 intact:EBI-3043908|ensembl:ENSMUSP00000018506|ensembl:ENSMUSP00000137310|uniprotkb:Q64292 psi-mi:clic4_human(display_long)|uniprotkb:CLIC4(gene name)|psi-mi:CLIC4(display_short)|uniprotkb:Intracellular chloride ion channel protein p64H1(gene name synonym) psi-mi:ima1_mouse(display_long)|uniprotkb:Kpna2(gene name)|psi-mi:Kpna2(display_short)|uniprotkb:Rch1(gene name synonym)|uniprotkb:Importin alpha P1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:Pendulin(gene name synonym)|uniprotkb:Pore targeting complex 58 kDa subunit(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Mynott et al. (2011) mint:MINT-8118090|pubmed:21388519|mint:fj-10-1097.r1 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8607039|mint:MINT-8118302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_039234.1|ensembl:ENSG00000169504(gene)|ensembl:ENST00000374379(transcript)|ensembl:ENST00000488683(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006821"(chloride transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045177"(apical part of cell)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030257|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:2AHE|rcsb pdb:2D2Z|rcsb pdb:3OQS|go:"GO:0048471"(perinuclear region of cytoplasm)|mint:MINT-8118304(identity) ensembl:ENSMUSG00000018362(gene)|ensembl:ENSMUSG00000066878(gene)|ensembl:ENSMUST00000018506(transcript)|ensembl:ENSMUST00000086423(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52293|rcsb pdb:1EJL|rcsb pdb:1EJY|rcsb pdb:1IAL|rcsb pdb:1IQ1|rcsb pdb:1PJM|rcsb pdb:1PJN|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1Y2A|rcsb pdb:2C1M|rcsb pdb:2YNR|rcsb pdb:3BTR|rcsb pdb:3KND|rcsb pdb:3L3Q|rcsb pdb:3OQS|rcsb pdb:3Q5U|rcsb pdb:3RZ9|rcsb pdb:3RZX|rcsb pdb:3TPM|rcsb pdb:3TPO|rcsb pdb:3UKW|rcsb pdb:3UKX|rcsb pdb:3UKZ|rcsb pdb:3UL0|rcsb pdb:3UL1|rcsb pdb:3UVU|rcsb pdb:3VE6|rcsb pdb:3ZIN|rcsb pdb:3ZIO|rcsb pdb:3ZIP|rcsb pdb:3ZIQ|rcsb pdb:3ZIR|rcsb pdb:4BA3|rcsb pdb:4HTV|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:4OIH|rcsb pdb:4U54|rcsb pdb:4U58|rcsb pdb:4U5L|rcsb pdb:4U5N|rcsb pdb:4U5O|rcsb pdb:4U5S|rcsb pdb:4U5U|rcsb pdb:4U5V|rcsb pdb:4UAF|rcsb pdb:4YI0|rcsb pdb:4ZDU|rcsb pdb:5B56|rcsb pdb:5CTT|rcsb pdb:5D5K|rcsb pdb:5E6Q|rcsb pdb:5EKF|rcsb pdb:5EKG|rcsb pdb:5FC8|rcsb pdb:5GXW|rcsb pdb:3UKY|rcsb pdb:5HHG|rcsb pdb:5HUW|rcsb pdb:5HUY|rcsb pdb:5K9S|rcsb pdb:5KLR|rcsb pdb:5SVZ|rcsb pdb:5U5P|rcsb pdb:5U5R|rcsb pdb:5UMZ|rcsb pdb:5V5O|rcsb pdb:5V5P|rcsb pdb:5W41|rcsb pdb:5W4E|rcsb pdb:5W4F|rcsb pdb:5W4G|rcsb pdb:5WUM|rcsb pdb:5WUN|rcsb pdb:5X8N|rcsb pdb:6BVT|rcsb pdb:6BW0|rcsb pdb:6BW1|rcsb pdb:6D7M|rcsb pdb:6D7N|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:5KLT|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|rcsb pdb:6MJL|rcsb pdb:6P6A|rcsb pdb:6P6E|rcsb pdb:6WX7|rcsb pdb:7JJM|rcsb pdb:7JK7|rcsb pdb:7JVO|rcsb pdb:7L04|reactome:R-MMU-5693548|refseq:NP_034785.1|dip:DIP-47774N|mint:MINT-8118305(identity) - - - comment:homomint|comment:mint|figure legend:t1 t2 f1 f2a f2b f2c sf1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/23 2014/10/16 rogid:l3XpkyJyCZrtsEKeqHkD548WRLs9606 rogid:qML5OVHqAJODiP+FSG9fTsiV3JQ10090 intact-crc:EFF84CF3B5FE9855|rigid:eLLNr2g+zVuARqfTwteUgsPWGvQ false binding-associated region:198-207(MINT-8118494) binding-associated region:70-529(MINT-8118521)|his tag:?-?(MINT-8118518) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant)