#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A1DRY3 uniprotkb:P36873-2 intact:EBI-4311408 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:a1dry3_human(display_long) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264662|imex:IM-17664-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR018247|interpro:IPR036770|refseq:NP_001287902.1 intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:5B-3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:oXf5vAP1LTlQ7fMiR/iYKYhqcT09606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:D610D38467965CCE|rigid:/qZLGw1EK+INra5YROjx/i70id0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36873-2 uniprotkb:P11142 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P78371 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P06576 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2 - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P63261 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422 - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P60709 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P07437 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P54652 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568 - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P36873-2 uniprotkb:P46439 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4312072|uniprotkb:A8K0V8|uniprotkb:Q6PD78|ensembl:ENSP00000256593 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:gstm5_human(display_long)|uniprotkb:GSTM5(gene name)|psi-mi:GSTM5(display_short)|uniprotkb:GST class-mu 5(gene name synonym)|uniprotkb:GSTM5-5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4312093|imex:IM-17664-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_000842.2|refseq:XP_005270841.1|ensembl:ENSG00000134201(gene)|ensembl:ENST00000256593(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|reactome:R-HSA-156590 - - - figure legend:table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:njZdYEkxcFLriZzOIJYVjKFo8rc9606 intact-crc:AE020705712477D5|rigid:fwu46joGs12sLbOiALd/z8hPQko false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96S59 intact:EBI-6266648 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 - psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:pp1g_chlae(display_short)|psi-mi:EBI-6266648(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264690|imex:IM-17664-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 uniprotkb:P36873(see-also) - - no-uniprot-update:|comment:"this protein was detected using an antibody to (gene) PPP1CC (human)" figure legend:5B-2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/07/28 2014/10/16 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 - intact-crc:CE849B3754E609A6 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5SWA1 intact:EBI-6266648 intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156 - psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short) psi-mi:pp1g_chlae(display_short)|psi-mi:EBI-6266648(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264704|imex:IM-17664-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000158615(gene)|ensembl:ENST00000367188(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR019512|interpro:IPR019523|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|go:"GO:0034976"(response to endoplasmic reticulum stress) uniprotkb:P36873(see-also) - - no-uniprot-update: figure legend:5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/07/28 2014/10/16 rogid:EBWZBipo2XhGvdskPjJVlLSo5T89606 - intact-crc:EADC47554CC3B8CC false green fluorescent protein tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7Z5V6 uniprotkb:P36873-2 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0047"(far western blotting) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264745|imex:IM-17664-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410 intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/28 2014/10/16 rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:3D07B8394623E87C|rigid:pJ47IC2Fqd8aU4HMlGNOxY3+OUU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5JR98 uniprotkb:P36873-1 intact:EBI-4311709|ensembl:ENSP00000341803|ensembl:ENSP00000501642 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:dylt4_human(display_long)|uniprotkb:DYNLT4(gene name)|psi-mi:DYNLT4(display_short)|uniprotkb:Protein N22.1(gene name synonym)|uniprotkb:TCTEX1D4(gene name synonym)|uniprotkb:Tctex-2-beta(gene name synonym)|uniprotkb:Tctex1 domain-containing protein 4(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0047"(far western blotting) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264734|imex:IM-17664-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013654.1|refseq:XP_011539677.1|refseq:XP_011539678.1|ensembl:ENSG00000188396(gene)|ensembl:ENST00000339355(transcript)|ensembl:ENST00000675259(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005930"(axoneme)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR005334(Tctex-1)|interpro:IPR038586 ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/07/28 2014/10/16 rogid:pfp60a4xhJsvZKmjtuzxuYYMi4k9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:8900DC782D19DE26|rigid:mJs7mLGBukGLSAd13P2Zb/ReMJ0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q4KMQ1 uniprotkb:P36873-1 intact:EBI-3942777|uniprotkb:Q5VSG5|uniprotkb:Q6IPP2|uniprotkb:B7ZKU5|uniprotkb:Q8NCH2|uniprotkb:Q5VSG6|ensembl:ENSP00000387100 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:tprn_human(display_long)|uniprotkb:TPRN(gene name)|psi-mi:TPRN(display_short)|uniprotkb:C9orf75(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311359|imex:IM-17664-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121700.2|ensembl:ENSG00000176058(gene)|ensembl:ENST00000409012(transcript)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032420"(stereocilium)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:0120045"(stereocilium maintenance)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|interpro:IPR033359|rcsb pdb:6Y9Q|reactome:R-HSA-9662360|reactome:R-HSA-9662361|entrezgene/locuslink:NM_173691(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:3Nmqnm7OeV1fScXSCIfR2xrHBeo9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:4B58C785495C1039|rigid:AvEi9lpamw4J+BSDeO3HSwbz7+g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6NYC8 uniprotkb:P36873-1 intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311364|imex:IM-17664-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8|entrezgene/locuslink:BC066644(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:999AA2440786B4E6|rigid:N/90dHpAqNy6ghY1L506bek4X2A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:P51955-1 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-687792|ensembl:ENSP00000355966 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:p51955-1(display_long)|uniprotkb:Nek2A(isoform synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NLK1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311374|imex:IM-17664-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) intact:EBI-633182(nek2_human)|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|entrezgene/locuslink:NM_002497(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 intact-crc:C03579BAC7B49718|rigid:VDNv9ytQx5O8yWCNO7/n7MmuIww false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:P51955 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311379|imex:IM-17664-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1|entrezgene/locuslink:AY863109(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 intact-crc:D67FDC6888CA3987|rigid:VDNv9ytQx5O8yWCNO7/n7MmuIww false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IWU2 uniprotkb:P36873-1 intact:EBI-2008933|uniprotkb:Q75MG7|uniprotkb:Q9UPS3|uniprotkb:A4D272|ensembl:ENSP00000297293 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:lmtk2_human(display_long)|uniprotkb:LMTK2(gene name)|psi-mi:LMTK2(display_short)|uniprotkb:AATYK2(gene name synonym)|uniprotkb:BREK(gene name synonym)|uniprotkb:KIAA1079(gene name synonym)|uniprotkb:KPI2(gene name synonym)|uniprotkb:LMR2(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KPI-2(gene name synonym)|uniprotkb:Kinase/phosphatase/inhibitor 2(gene name synonym)|uniprotkb:Apoptosis-associated tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)|uniprotkb:CDK5/p35-regulated kinase(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311369|imex:IM-17664-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055731.2|ensembl:ENSG00000164715(gene)|ensembl:ENST00000297293(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8IWU2|entrezgene/locuslink:NM_014916(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:oD9P04WV3KZ1/8TW4eDYqqNqDkA9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:32817020DE3A541E|rigid:XGN0XFn6/Oxpl1yFTOlIeFf3Sbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:A1DRY3 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-4311408 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:a1dry3_human(display_long) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311411|imex:IM-17664-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR018247|interpro:IPR036770|refseq:NP_001287902.1|entrezgene/locuslink:EF041819(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:oXf5vAP1LTlQ7fMiR/iYKYhqcT09606 intact-crc:41771CA6649254F9|rigid:li+1s682RJg5keilw4sZaK6p9ok false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60674 uniprotkb:P36873-1 intact:EBI-518647|uniprotkb:O14636|uniprotkb:O75297|intact:EBI-28977715|ensembl:ENSP00000371067 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:jak2_human(display_long)|uniprotkb:Janus kinase 2(gene name synonym)|uniprotkb:JAK2(gene name)|psi-mi:JAK2(display_short) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311421|imex:IM-17664-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309133.1|ensembl:ENSG00000096968(gene)|ensembl:ENST00000381652(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000791"(euchromatin)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005143"(interleukin-12 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSP00000371067|refseq:NP_004963.1|refseq:NP_001309123.1|refseq:NP_001309124.1|refseq:NP_001309125.1|dip:DIP-33880N|go:"GO:0005730"(nucleolus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031904"(endosome lumen)|go:"GO:0031959"(mineralocorticoid receptor signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035401"("histone kinase activity (H3-Y41 specific)")|go:"GO:0035409"(histone H3-Y41 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070671"(response to interleukin-12)|go:"GO:0070757"(interleukin-35-mediated signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR020693|interpro:IPR035588|interpro:IPR035589|interpro:IPR035860|interpro:IPR035963|interpro:IPR036860|interpro:IPR037838|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:O60674|rcsb pdb:2B7A|rcsb pdb:2W1I|rcsb pdb:2XA4|rcsb pdb:3E62|rcsb pdb:3E63|rcsb pdb:3E64|rcsb pdb:3FUP|rcsb pdb:3IO7|rcsb pdb:3IOK|rcsb pdb:3JY9|rcsb pdb:3KCK|rcsb pdb:3KRR|rcsb pdb:3LPB|rcsb pdb:3Q32|rcsb pdb:3RVG|rcsb pdb:3TJC|rcsb pdb:3TJD|rcsb pdb:3UGC|rcsb pdb:3ZMM|rcsb pdb:4AQC|rcsb pdb:4BBE|rcsb pdb:4BBF|rcsb pdb:4C61|rcsb pdb:4C62|rcsb pdb:4D0W|rcsb pdb:4D0X|rcsb pdb:4D1S|rcsb pdb:4E4M|rcsb pdb:4E6D|rcsb pdb:4E6Q|rcsb pdb:4F08|rcsb pdb:4F09|rcsb pdb:4FVP|rcsb pdb:4FVQ|rcsb pdb:4FVR|rcsb pdb:4GFM|rcsb pdb:4GMY|rcsb pdb:4HGE|rcsb pdb:4IVA|rcsb pdb:4JI9|rcsb pdb:4JIA|rcsb pdb:4P7E|rcsb pdb:4YTC|rcsb pdb:4YTF|rcsb pdb:4YTH|rcsb pdb:4YTI|rcsb pdb:4Z32|rcsb pdb:4ZIM|rcsb pdb:5CF4|rcsb pdb:5CF5|rcsb pdb:5CF6|rcsb pdb:5CF8|rcsb pdb:5HEZ|rcsb pdb:5I4N|rcsb pdb:5L3A|rcsb pdb:5TQ3|rcsb pdb:5TQ4|rcsb pdb:5TQ5|rcsb pdb:5TQ6|rcsb pdb:5TQ7|rcsb pdb:5TQ8|rcsb pdb:5USY|rcsb pdb:5USZ|rcsb pdb:5UT0|rcsb pdb:5UT1|rcsb pdb:5UT2|rcsb pdb:5UT3|rcsb pdb:5UT4|rcsb pdb:5UT5|rcsb pdb:5UT6|rcsb pdb:5WEV|rcsb pdb:5WIJ|rcsb pdb:5WIK|rcsb pdb:5WIL|rcsb pdb:5WIM|rcsb pdb:5WIN|rcsb pdb:6AAJ|rcsb pdb:6BBV|rcsb pdb:6BRW|rcsb pdb:6BS0|rcsb pdb:6BSS|rcsb pdb:6D2I|rcsb pdb:6DRW|rcsb pdb:6E2P|rcsb pdb:6E2Q|rcsb pdb:6G3C|rcsb pdb:6M9H|rcsb pdb:6OAV|rcsb pdb:6OBB|rcsb pdb:6OBF|rcsb pdb:6OBL|rcsb pdb:6OCC|rcsb pdb:6TPD|rcsb pdb:6VGL|rcsb pdb:6VN8|rcsb pdb:6VNB|rcsb pdb:6VNC|rcsb pdb:6VNE|rcsb pdb:6VNF|rcsb pdb:6VNG|rcsb pdb:6VNH|rcsb pdb:6VNI|rcsb pdb:6VNJ|rcsb pdb:6VNK|rcsb pdb:6VNL|rcsb pdb:6VNM|rcsb pdb:6VS3|rcsb pdb:6VSN|rcsb pdb:6WTN|rcsb pdb:6WTO|rcsb pdb:6WTP|rcsb pdb:6WTQ|rcsb pdb:6X8E|rcsb pdb:6XJK|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1170546|reactome:R-HSA-1433557|reactome:R-HSA-2586552|reactome:R-HSA-3214858|reactome:R-HSA-512988|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-6802946|rcsb pdb:5AEP|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-69231|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9006335|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912526|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983231|entrezgene/locuslink:AF058925(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:s2LnvkFxriuFzkRSlP9PI0h/wYk9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:ED9647C3D39BBFC0|rigid:5JnwzBeQ4fLzrwmMxdcSk1wLTP0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q96KQ4 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-1105153|uniprotkb:B2RMX5|uniprotkb:O94870|ensembl:ENSP00000202556 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:aspp1_human(display_long)|uniprotkb:PPP1R13B(gene name)|psi-mi:PPP1R13B(display_short)|uniprotkb:ASPP1(gene name synonym)|uniprotkb:KIAA0771(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 13B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311393|imex:IM-17664-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) ensembl:ENSG00000088808(gene)|ensembl:ENST00000202556(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028319|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|rcsb pdb:6HL5|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|refseq:NP_056131.2|entrezgene/locuslink:NM_015316(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:68vrjCXCm2NiwUih4QbAqeT3Jj49606 intact-crc:26893738826AD6C2|rigid:2uIkMSWiSJCzghbydtf6SE9ZNWI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q5SWA1 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311398|imex:IM-17664-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) ensembl:ENSG00000158615(gene)|ensembl:ENST00000367188(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR019512|interpro:IPR019523|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|go:"GO:0034976"(response to endoplasmic reticulum stress)|entrezgene/locuslink:NM_032833(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:EBWZBipo2XhGvdskPjJVlLSo5T89606 intact-crc:48846D52BBB3BCF3|rigid:ipKP+KfL1II+vYOhAMzrr7zEwU8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13625 uniprotkb:P36873-1 intact:EBI-77642|uniprotkb:Q12892|uniprotkb:Q86X75|uniprotkb:Q96KQ3|uniprotkb:B4DG66 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:aspp2_human(display_long)|uniprotkb:TP53BP2(gene name)|psi-mi:TP53BP2(display_short)|uniprotkb:ASPP2(gene name synonym)|uniprotkb:BBP(gene name synonym)|uniprotkb:Tumor suppressor p53-binding protein 2(gene name synonym)|uniprotkb:Bcl2-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-51(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311388|imex:IM-17664-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026855.2|refseq:NP_005417.1|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|rcsb pdb:1YCS|rcsb pdb:2UWQ|rcsb pdb:4A63|rcsb pdb:4IRV|rcsb pdb:6GHM|rcsb pdb:6HKP|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|ensembl:ENST00000343537|ensembl:ENSP00000341957|ensembl:ENSG00000143514|ensembl:ENST00000391878|ensembl:ENSP00000375750|refseq:XP_011542571.1|dip:DIP-426N|mint:Q13625|entrezgene/locuslink:NM_005426(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:p3shTkfKZ6Ipy/xOQok7jfGD9vg9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:12F908F0A14AE7B6|rigid:EWQEJEp63l5WWD92Fzm5eSb7ELk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:P49750 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-712871|ensembl:ENSP00000324463|uniprotkb:P49752|uniprotkb:Q96I64|uniprotkb:Q9P1V7 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:ylpm1_human(display_long)|uniprotkb:Nuclear protein ZAP3(gene name synonym)|uniprotkb:ZAP113(gene name synonym)|uniprotkb:YLPM1(gene name)|psi-mi:YLPM1(display_short)|uniprotkb:C14orf170(gene name synonym)|uniprotkb:ZAP3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311416|imex:IM-17664-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) ensembl:ENSG00000119596(gene)|ensembl:ENST00000325680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0032204"(regulation of telomere maintenance)|interpro:IPR026314|interpro:IPR027417|refseq:NP_062535.2|ensembl:ENSP00000324463|dip:DIP-53676N|entrezgene/locuslink:NM_019589(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2018/04/06 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:3w+7odPC5D2UQYimwmCgTBbvWR49606 intact-crc:E850BFBA800184FD|rigid:f0cNT7bMykW6vQkSgmwKfs9Avyw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q5UIP0 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311403|imex:IM-17664-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|entrezgene/locuslink:NM_018151(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606 intact-crc:ADD53A0F45363938|rigid:6EZ4qIum5A/xygwaWN1Kc9j9yBw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q2T9L4 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-4311436|ensembl:ENSP00000457205 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:insy1_human(display_long)|uniprotkb:INSYN1(gene name)|psi-mi:INSYN1(display_short)|uniprotkb:C15orf59(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311440|imex:IM-17664-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_001034703.1|ensembl:ENSG00000205363(gene)|go:"GO:0014069"(postsynaptic density)|go:"GO:0060080"(inhibitory postsynaptic potential)|interpro:IPR027997|ensembl:ENST00000569673(transcript)|refseq:XP_005254426.1|entrezgene/locuslink:NM_001039614(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:TLCfPVwPEwvSPDQirpDo9iQKnZM9606 intact-crc:DF0E4B50C5E809CE|rigid:Ei75XuhXIM5IfuzwJ7ICoq5D9Yk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:O75182 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311431|imex:IM-17664-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1|entrezgene/locuslink:BC001205(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 intact-crc:C4F2B215D0B34536|rigid:J9QIYMvsxG/UheAcLZ8mbzY4qfs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:P41236 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-1056517|ensembl:ENSP00000484580 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:ipp2_human(display_long)|uniprotkb:PPP1R2(gene name)|psi-mi:PPP1R2(display_short)|uniprotkb:IPP2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311471|imex:IM-17664-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_006232.1|ensembl:ENSG00000184203(gene)|ensembl:ENST00000618156(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)")|refseq:NP_001303254.1|dip:DIP-781N|entrezgene/locuslink:NT_007592(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:Kf816t+iy7T4OA28eT6cN4v471s9606 intact-crc:E5CB3168D82DFB20|rigid:LtHcsVSn8L1Hi/ZLXjZeLdA7MAc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17028 uniprotkb:P36873-1 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311466|imex:IM-17664-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|entrezgene/locuslink:AK021966(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:A31E6A0875A87566|rigid:zuohHIjG/S1krkagg06LCtbr8uY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q86US8 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-3232100|ensembl:ENSP00000263073|uniprotkb:O94837|uniprotkb:Q9UF60|uniprotkb:Q86VH6|uniprotkb:B7Z874 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:est1a_human(display_long)|uniprotkb:SMG6(gene name)|psi-mi:SMG6(display_short)|uniprotkb:C17orf31(gene name synonym)|uniprotkb:EST1A(gene name synonym)|uniprotkb:KIAA0732(gene name synonym)|uniprotkb:EST1-like protein A(gene name synonym)|uniprotkb:Ever shorter telomeres 1A(gene name synonym)|uniprotkb:Smg-6 homolog(gene name synonym)|uniprotkb:Telomerase subunit EST1A(gene name synonym)|uniprotkb:hSmg5/7a(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311426|imex:IM-17664-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) ensembl:ENST00000263073(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|interpro:IPR029060|mint:Q86US8|rcsb pdb:2DOK|rcsb pdb:2HWW|rcsb pdb:2HWX|rcsb pdb:4UM2|reactome:R-HSA-975957|ensembl:ENSG00000070366(gene)|refseq:XP_011522071.1|refseq:XP_011522077.1|refseq:NP_060045.4|refseq:NP_001243756.1|refseq:NP_001243757.1|refseq:NP_001269255.1|refseq:XP_005256626.1|refseq:XP_005256628.1|refseq:XP_016879888.1|entrezgene/locuslink:NM_017575(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:UoAA9ikMFv3EHZZozUAOkWWPrRM9606 intact-crc:4275B85964F94C21|rigid:iBlEc1awVdSsnTpUdbf0xdQ8j3o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q8TAP8 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-4311445|uniprotkb:A4D2C5|intact:EBI-28969042|ensembl:ENSP00000292330 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:ppr35_human(display_long)|uniprotkb:PPP1R35(gene name)|psi-mi:PPP1R35(display_short)|uniprotkb:C7orf47(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311450|imex:IM-17664-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_659467.1|ensembl:ENSP00000292330|ensembl:ENSG00000160813(gene)|ensembl:ENST00000292330(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|interpro:IPR029135|interpro:IPR033590|entrezgene/locuslink:NM_145030(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:2P9EODxUIbPGxtH3r0zMNU2IXtI9606 intact-crc:ACCD35C27CA81CCA|rigid:0Rfjfgpl6Xlre7xk5bEvvn8+6OM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5SZB4 uniprotkb:P36873-1 intact:EBI-4311456|uniprotkb:Q8NA65|uniprotkb:Q2M1I2|ensembl:ENSP00000361556 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:ci050_human(display_long)|uniprotkb:C9orf50(gene name)|psi-mi:C9orf50(display_short) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311455|imex:IM-17664-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_955382.3|ensembl:ENSG00000179058(gene)|ensembl:ENST00000372478(transcript)|interpro:IPR032756|refseq:XP_011516957.1|refseq:XP_011516958.1|entrezgene/locuslink:NM_199350(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:KiEzRlUJMgGUSIvEGuL0P7Y8XUo9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:0E000ECEC772EDF4|rigid:fXxXMXHmgKBSpAKhxhg/5xcmoIE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TEC5 uniprotkb:P36873-1 intact:EBI-2130111|uniprotkb:A8K961|uniprotkb:Q08AM9|uniprotkb:Q6GMR9|uniprotkb:Q8N5S8|uniprotkb:Q96LP8|ensembl:ENSP00000352028|ensembl:ENSP00000424497 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:sh3r2_human(display_long)|uniprotkb:POSH-eliminating RING protein(gene name synonym)|uniprotkb:POSH3(gene name synonym)|uniprotkb:POSHER(gene name synonym)|uniprotkb:SH3RF2(gene name)|psi-mi:SH3RF2(display_short)|uniprotkb:Heart protein phosphatase 1-binding protein(gene name synonym)|uniprotkb:PPP1R39(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 39(gene name synonym)|uniprotkb:RING finger protein 158(gene name synonym)|uniprotkb:RNF158(gene name synonym)|uniprotkb:SH3 domain-containing RING finger protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SH3RF2(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311476|imex:IM-17664-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011535871.1|refseq:NP_689763.3|refseq:XP_016864625.1|refseq:XP_006714820.1|ensembl:ENSG00000156463(gene)|ensembl:ENST00000359120(transcript)|ensembl:ENST00000511217(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR028511|interpro:IPR035792|interpro:IPR035794|interpro:IPR035822|interpro:IPR036028|entrezgene/locuslink:BC073914(identity) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:ipP8ZHmrTHHf+77eHJSoHFA45449606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:1A19516A0AF6228F|rigid:3VzfcxVGKXL7uzFfZ+VXBXeDsss false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-1 uniprotkb:Q9P2P6 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-718809|uniprotkb:Q9UF70|uniprotkb:Q68DG2|uniprotkb:Q6AI01|uniprotkb:Q6ZWK0|ensembl:ENSP00000290607 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:star9_human(display_long)|uniprotkb:START domain-containing protein 9(gene name synonym)|uniprotkb:STARD9(gene name)|psi-mi:STARD9(display_short)|uniprotkb:KIAA1300(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311481|imex:IM-17664-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_065810.2|ensembl:ENSP00000290607|ensembl:ENSG00000159433(gene)|ensembl:ENST00000290607(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0051225"(spindle assembly)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR023393|interpro:IPR027417|interpro:IPR036961|interpro:IPR042990|entrezgene/locuslink:XM_001129482(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:N7cUxVyUPfN8YNsMYXpb66WI/Sg9606 intact-crc:9A20ECAA2FD6E3C4|rigid:Rva48WcTy8V/nq7AXm024628nrk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q6NYC8 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311513|imex:IM-17664-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8|entrezgene/locuslink:BC066644(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606 intact-crc:92F7B1199BC45989|rigid:vwd9GKkF/aVinaA08A4D35b8YBc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:P51955-1 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-687792|ensembl:ENSP00000355966 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:p51955-1(display_long)|uniprotkb:Nek2A(isoform synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NLK1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311518|imex:IM-17664-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) intact:EBI-633182(nek2_human)|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|entrezgene/locuslink:NM_002497(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 intact-crc:4896E2D7D4E90B5A|rigid:dgW5o8LY6L+tldfNNwtxYJtsm/Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GX9 uniprotkb:P36873-2 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311559|imex:IM-17664-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|entrezgene/locuslink:NM_015957(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:7447B810516E1FEF|rigid:Fftj2mWInO/0TvXo2eGj/dDKIfk false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q13625 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-77642|uniprotkb:Q12892|uniprotkb:Q86X75|uniprotkb:Q96KQ3|uniprotkb:B4DG66 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:aspp2_human(display_long)|uniprotkb:TP53BP2(gene name)|psi-mi:TP53BP2(display_short)|uniprotkb:ASPP2(gene name synonym)|uniprotkb:BBP(gene name synonym)|uniprotkb:Tumor suppressor p53-binding protein 2(gene name synonym)|uniprotkb:Bcl2-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-51(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311528|imex:IM-17664-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001026855.2|refseq:NP_005417.1|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|rcsb pdb:1YCS|rcsb pdb:2UWQ|rcsb pdb:4A63|rcsb pdb:4IRV|rcsb pdb:6GHM|rcsb pdb:6HKP|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|ensembl:ENST00000343537|ensembl:ENSP00000341957|ensembl:ENSG00000143514|ensembl:ENST00000391878|ensembl:ENSP00000375750|refseq:XP_011542571.1|dip:DIP-426N|mint:Q13625|entrezgene/locuslink:NM_005426(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:p3shTkfKZ6Ipy/xOQok7jfGD9vg9606 intact-crc:DAFE292245A2716C|rigid:xeuEdG/9atDAI8UNOZtqAs3oz68 false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q38J66 uniprotkb:P36873-2 intact:EBI-4311545 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:q38j66_human(display_long)|uniprotkb:PPP1R8(gene name)|psi-mi:PPP1R8(display_short) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311549|imex:IM-17664-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:DQ223931(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:ObNJSaRxb57e4VOa2mGqlIVKdV89606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:319FAFC6A841565E|rigid:Em+AJ6Xy3zJkTDg/oStfuW0H1Mk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q5UIP0 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311554|imex:IM-17664-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|entrezgene/locuslink:NM_018151(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606 intact-crc:A6B82952D974D457|rigid:chut8VngLgSdg/YsdECNyfxUN7I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51955 uniprotkb:P36873-2 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311523|imex:IM-17664-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1|entrezgene/locuslink:AY863109(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:DD12CF351488D4E8|rigid:dgW5o8LY6L+tldfNNwtxYJtsm/Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q96KQ4 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-1105153|uniprotkb:B2RMX5|uniprotkb:O94870|ensembl:ENSP00000202556 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:aspp1_human(display_long)|uniprotkb:PPP1R13B(gene name)|psi-mi:PPP1R13B(display_short)|uniprotkb:ASPP1(gene name synonym)|uniprotkb:KIAA0771(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 13B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311535|imex:IM-17664-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) ensembl:ENSG00000088808(gene)|ensembl:ENST00000202556(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028319|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|rcsb pdb:6HL5|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|refseq:NP_056131.2|entrezgene/locuslink:NM_015316(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:68vrjCXCm2NiwUih4QbAqeT3Jj49606 intact-crc:2DE424651E283BAD|rigid:SiLWVA1BgR6a5fvxUX9z3iygtw0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q5SWA1 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311540|imex:IM-17664-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) ensembl:ENSG00000158615(gene)|ensembl:ENST00000367188(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR019512|interpro:IPR019523|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|go:"GO:0034976"(response to endoplasmic reticulum stress)|entrezgene/locuslink:NM_032833(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:EBWZBipo2XhGvdskPjJVlLSo5T89606 intact-crc:43E97E0F27F1519C|rigid:dvLP+gSdgXyz1uAMoWX6C+B0mbQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92905 uniprotkb:P36873-2 intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311588|imex:IM-17664-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|entrezgene/locuslink:NM_006837(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:7C05F4D75B034439|rigid:4KJQ1aig/EJRGp/W9LUtRofZmYg false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7L576 uniprotkb:P36873-2 intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779|ensembl:ENSP00000481038|ensembl:ENSP00000499947|ensembl:ENSP00000500331 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311602|imex:IM-17664-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749(gene)|ensembl:ENSG00000288461(gene)|ensembl:ENST00000610365(transcript)|ensembl:ENST00000617928(transcript)|ensembl:ENST00000671714(transcript)|ensembl:ENST00000672091(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031209"(SCAR complex)|go:"GO:0005576"(extracellular region)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0005829"(cytosol)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N|entrezgene/locuslink:NM_014608(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:DC5181D36E4F4395|rigid:PzfpD4jPM76nxi79mXOzAhI2YbM false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBL3 uniprotkb:P36873-2 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311566|imex:IM-17664-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|entrezgene/locuslink:NM_004674(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:D884B90B615AEA06|rigid:DpEPoz3a2oI0HFi7rZeGZFxwLBQ false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q96S65 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311573|uniprotkb:Q69YY5|ensembl:ENSP00000273153|ensembl:ENSP00000422532 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:csrn1_human(display_long)|uniprotkb:CSRNP1(gene name)|psi-mi:CSRNP1(display_short)|uniprotkb:AXUD1(gene name synonym)|uniprotkb:TAIP3(gene name synonym)|uniprotkb:Axin-1 up-regulated gene 1 protein(gene name synonym)|uniprotkb:Protein URAX1(gene name synonym)|uniprotkb:TGF-beta-induced apoptosis protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311578|imex:IM-17664-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001307489.1|refseq:NP_149016.2|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|interpro:IPR023260|interpro:IPR031972|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|ensembl:ENSG00000144655(gene)|ensembl:ENST00000273153(transcript)|ensembl:ENST00000514182(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSP00000273153|ensembl:ENSP00000422532|refseq:XP_016862537.1|entrezgene/locuslink:NM_033027(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:+mVQ6ovyrpL1YUvHLnr2MS1Nme89606 intact-crc:492EFFAC9451C1DD|rigid:71wnCVey0XAbHafc6jmIHDSHJxM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:P07711 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-1220160|uniprotkb:Q6IAV1|uniprotkb:Q96QJ0|ensembl:ENSP00000345344|ensembl:ENSP00000365061|ensembl:ENSP00000502901|ensembl:ENSP00000502968|ensembl:ENSP00000503298|ensembl:ENSP00000503439|ensembl:ENSP00000503897|ensembl:ENSP00000503938|ensembl:ENSP00000504279|ensembl:ENSP00000504313|ensembl:ENSP00000503470|ensembl:ENSP00000503851 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:catl1_human(display_long)|uniprotkb:CTSL(gene name)|psi-mi:CTSL(display_short)|uniprotkb:CTSL1(gene name synonym)|uniprotkb:Major excreted protein(gene name synonym)|uniprotkb:Cathepsin L1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311595|imex:IM-17664-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001244900.1|refseq:NP_001244901.1|refseq:NP_001903.1|refseq:NP_666023.1|refseq:XP_005251773.1|ensembl:ENSG00000135047(gene)|ensembl:ENST00000340342(transcript)|ensembl:ENST00000343150(transcript)|ensembl:ENST00000676480(transcript)|ensembl:ENST00000676531(transcript)|ensembl:ENST00000676881(transcript)|ensembl:ENST00000676946(transcript)|ensembl:ENST00000677262(transcript)|ensembl:ENST00000677761(transcript)|ensembl:ENST00000677821(transcript)|ensembl:ENST00000678442(transcript)|ensembl:ENST00000679149(transcript)|ensembl:ENST00000679157(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006955"(immune response)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031638"(zymogen activation)|go:"GO:0034230"(enkephalin processing)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042583"(chromaffin granule)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043373"(CD4-positive, alpha-beta T cell lineage commitment)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048002"(antigen processing and presentation of peptide antigen)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060309"(elastin catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0071888"(macrophage apoptotic process)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097655"(serpin family protein binding)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|interpro:IPR039417|rcsb pdb:1CJL|rcsb pdb:1CS8|rcsb pdb:1ICF|rcsb pdb:1MHW|rcsb pdb:2NQD|rcsb pdb:2VHS|rcsb pdb:2XU1|rcsb pdb:2XU3|rcsb pdb:2XU4|rcsb pdb:2XU5|rcsb pdb:2YJ2|rcsb pdb:2YJ8|rcsb pdb:2YJ9|rcsb pdb:2YJB|rcsb pdb:2YJC|rcsb pdb:3H89|rcsb pdb:3H8B|rcsb pdb:3H8C|rcsb pdb:3HHA|rcsb pdb:3HWN|rcsb pdb:3IV2|rcsb pdb:3K24|rcsb pdb:3KSE|rcsb pdb:3OF8|rcsb pdb:3OF9|rcsb pdb:4AXL|rcsb pdb:4AXM|rcsb pdb:5F02|rcsb pdb:5I4H|rcsb pdb:5MAE|rcsb pdb:5MAJ|rcsb pdb:5MQY|rcsb pdb:6EZP|rcsb pdb:6EZX|rcsb pdb:6F06|rcsb pdb:6JD0|rcsb pdb:6JD8|reactome:R-HSA-1236977|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-8939242|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:3BC3|entrezgene/locuslink:NM_001912(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:4ASJZ/S9LTLUCO4cGa+6q3vMyEE9606 intact-crc:79B9A096F5FE05D7|rigid:ZmqgGUiPSDWa96L+axJ2nwArgf8 false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02745 uniprotkb:P36873-2 intact:EBI-1220209|uniprotkb:Q5T963|uniprotkb:B2R4X2|ensembl:ENSP00000363773|ensembl:ENSP00000385564 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:c1qa_human(display_long)|uniprotkb:C1QA(gene name)|psi-mi:C1QA(display_short) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311583|imex:IM-17664-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057075.1|refseq:NP_001334394.1|refseq:NP_001334395.1|ensembl:ENSG00000173372(gene)|ensembl:ENST00000374642(transcript)|ensembl:ENST00000402322(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0010039"(response to iron ion)|go:"GO:0016322"(neuron remodeling)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048143"(astrocyte activation)|go:"GO:0050808"(synapse organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR037572|rcsb pdb:1PK6|rcsb pdb:2JG8|rcsb pdb:2JG9|rcsb pdb:2WNU|rcsb pdb:2WNV|rcsb pdb:5HKJ|rcsb pdb:5HZF|rcsb pdb:6FCZ|rcsb pdb:6Z6V|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|entrezgene/locuslink:NM_015991(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:JOnVJ11QPTmKEEGIr3BAlb2j6+s9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:9AAB52EACBB5626E|rigid:Vh468Qh8FVQceUVKBN9+O9HmHk0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UWU2 uniprotkb:P36873-2 intact:EBI-4311622|uniprotkb:Q96DR0|ensembl:ENSP00000295759|ensembl:ENSP00000375939 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:glb1l_human(display_long)|uniprotkb:GLB1L(gene name)|psi-mi:GLB1L(display_short)|uniprotkb:UNQ229/PRO262(orf name) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311621|imex:IM-17664-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273352.1|refseq:NP_078782.3|ensembl:ENSG00000163521(gene)|ensembl:ENST00000295759(transcript)|ensembl:ENST00000392089(transcript)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005773"(vacuole)|go:"GO:0005975"(carbohydrate metabolic process)|interpro:IPR001944(Glycoside hydrolase, family 35)|interpro:IPR008979(Galactose-binding like)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR026283|interpro:IPR031330|reactome:R-HSA-1660662|reactome:R-HSA-2022857|reactome:R-HSA-2024096|refseq:XP_016860384.1|entrezgene/locuslink:NM_024506(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:pm8Iv1eqSYc2azRlgBxM20XkcYo9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:97DFFDDF9C511443|rigid:47vybOHYw7Vfe1xyM5gflh/knQs false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NR20 uniprotkb:P36873-2 intact:EBI-3914009|uniprotkb:A8K8F7|uniprotkb:Q92631|uniprotkb:Q8NEF2|ensembl:ENSP00000010132|ensembl:ENSP00000441755 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:dyrk4_human(display_long)|uniprotkb:DYRK4(gene name)|psi-mi:DYRK4(display_short) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311614|imex:IM-17664-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003836.1|ensembl:ENSG00000010219(gene)|ensembl:ENST00000010132(transcript)|ensembl:ENST00000540757(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042521|entrezgene/locuslink:NM_003845(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:xfWtQZ5JGk38qm2cfJuF/SZNrb09606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:2EE113E8701FF568|rigid:we88AQsdCqiCoWFa5tId9+yhWWc false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NYF0 uniprotkb:P36873-2 intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311609|imex:IM-17664-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1|entrezgene/locuslink:NM_016651(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:9586977D68F724BB|rigid:Bf5XX0eJnc+VVzbBREIQm54f+Iw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:O43708 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-748043|uniprotkb:A6NNB8|uniprotkb:B2RCK3|uniprotkb:O15308|uniprotkb:O75430|uniprotkb:Q7Z610|uniprotkb:Q9BV63|uniprotkb:A8MWD7|uniprotkb:Q6IB17|uniprotkb:A6NED0 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:maai_human(display_long)|uniprotkb:Glutathione S-transferase zeta 1(gene name synonym)|uniprotkb:GSTZ1-1(gene name synonym)|uniprotkb:GSTZ1(gene name)|psi-mi:GSTZ1(display_short)|uniprotkb:MAAI(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311633|imex:IM-17664-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) reactome:R-HSA-204174|refseq:NP_665877.1|refseq:NP_665878.2|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR005955(Maleylacetoacetate isomerase)|rcsb pdb:1FW1|refseq:NP_001299589.1|interpro:IPR034330|interpro:IPR034333|reactome:R-HSA-8963684|interpro:IPR004046(Glutathione S-transferase, C-terminal)|reactome:R-HSA-156590|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016034"(maleylacetoacetate isomerase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|entrezgene/locuslink:NM_145870(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:Amk1E7K2v0Uo0k5XvLtBymmuxyk9606 intact-crc:B6EA1900DAED418A|rigid:vJj1BipNvc7vyQu5DstAtuxapis false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WXF2 uniprotkb:P36873-2 intact:EBI-4311641 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:q8wxf2_human(display_long) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311640|imex:IM-17664-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:AF447582(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:E0P8N4Yjr+V64P3iEXe0KEVw4ME9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:B2F72C820265DE89|rigid:PlMHiKnw9WjxEqv++WGSo6eCsa4 false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95819 uniprotkb:P36873-2 intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311665|imex:IM-17664-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579|entrezgene/locuslink:NM_004834(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:0B6E2B3EBFC9505A|rigid:eqyx0P2ktdOZ2Giw02YOcq+SIHg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BS83 uniprotkb:P36873-2 intact:EBI-4311671 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:q9bs83_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311670|imex:IM-17664-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR022677|interpro:IPR022678|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0006499"(N-terminal protein myristoylation)|entrezgene/locuslink:BC005232(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:LrZXBXFwKUkC7ugyGFjjWz77Ghg9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:584EA999DC66BFDB|rigid:L8AVXmELD1T2ZxugufLcHSni0fo false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q96S59 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311688|imex:IM-17664-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1|entrezgene/locuslink:NM_005493(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 intact-crc:851A06AEC00DF347|rigid:mWcen83XCqOvAI4BgSwEgxbIdWM false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6B0I6 uniprotkb:P36873-2 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311650|imex:IM-17664-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N|entrezgene/locuslink:NM_018039(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:1BD71C4D2AD4AD10|rigid:r1Hf7mE9n5FNi/Mirw639FBKwWY false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHY1 uniprotkb:P36873-2 intact:EBI-749731|uniprotkb:Q53FZ5|uniprotkb:Q96SU3|uniprotkb:B3KV40|uniprotkb:D6W558|ensembl:ENSP00000233557|ensembl:ENSP00000369181 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:nrbp_human(display_long)|uniprotkb:NRBP1(gene name)|psi-mi:NRBP1(display_short)|uniprotkb:BCON3(gene name synonym)|uniprotkb:NRBP(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311681|imex:IM-17664-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037524.1|refseq:NP_001308286.1|refseq:NP_001308287.1|refseq:NP_001308288.1|refseq:NP_001308290.1|refseq:NP_001308291.1|refseq:NP_001308292.1|ensembl:ENSG00000115216(gene)|ensembl:ENST00000233557(transcript)|ensembl:ENST00000379852(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-383280|entrezgene/locuslink:NM_013392(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:goSncKy0TZmmVuw5UPUDsCiAzkk9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:DB2A70C7F8520096|rigid:X1+lhw9oWD4XaUQ1wMZpVVsUzF8 false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JR98 uniprotkb:P36873-2 intact:EBI-4311709|ensembl:ENSP00000341803|ensembl:ENSP00000501642 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:dylt4_human(display_long)|uniprotkb:DYNLT4(gene name)|psi-mi:DYNLT4(display_short)|uniprotkb:Protein N22.1(gene name synonym)|uniprotkb:TCTEX1D4(gene name synonym)|uniprotkb:Tctex-2-beta(gene name synonym)|uniprotkb:Tctex1 domain-containing protein 4(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311713|imex:IM-17664-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013654.1|refseq:XP_011539677.1|refseq:XP_011539678.1|ensembl:ENSG00000188396(gene)|ensembl:ENST00000339355(transcript)|ensembl:ENST00000675259(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005930"(axoneme)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|entrezgene/locuslink:NM_001013632(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:pfp60a4xhJsvZKmjtuzxuYYMi4k9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:46392EABA829A042|rigid:fgWrkBAxJO3zFVbO8ZSKiqt+uYs false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23921 uniprotkb:P36873-2 intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311695|imex:IM-17664-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N|entrezgene/locuslink:NM_001033(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:D6F842EE87EF496A|rigid:u/eo4pfUsL2UCl734rESRaV1x0c false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q92547 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311727|imex:IM-17664-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N|entrezgene/locuslink:NM_007027(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606 intact-crc:B6BB2D3B1D52B2F8|rigid:la5tDwX9FoANdJ7pqiBCe7SrfwY false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BXJ8 uniprotkb:P36873-2 intact:EBI-727322|uniprotkb:Q8N6P1|uniprotkb:Q86TE9|ensembl:ENSP00000473983 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:tacan_human(display_long)|uniprotkb:TMPIT(gene name synonym)|uniprotkb:Transmembrane protein induced by tumor necrosis factor alpha(gene name synonym)|uniprotkb:TMEM120A(gene name)|psi-mi:TMEM120A(display_short)|uniprotkb:TACAN(gene name synonym)|uniprotkb:Transmembrane protein 120A(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311720|imex:IM-17664-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000189077(gene)|ensembl:ENST00000493111(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR012926(TMPIT-like)|rcsb pdb:7F3T|rcsb pdb:7F3U|refseq:NP_114131.1|entrezgene/locuslink:NM_031925(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:UCV6gXEdpg3gQOuhg+D5eBEY7Ww9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:9FFB9ED352EFC012|rigid:oiio+VSq+DtiRNEG3XloR1CkUTw false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43556 uniprotkb:P36873-2 intact:EBI-718097|uniprotkb:D6W5Q8|uniprotkb:Q75MH8|uniprotkb:B2R8N2|uniprotkb:Q8NFG8|uniprotkb:Q8WW28|uniprotkb:G5E9K6|uniprotkb:E9PF60|uniprotkb:Q6L8P0|intact:EBI-28976016|ensembl:ENSP00000497130 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:sgce_human(display_long)|uniprotkb:UNQ433/PRO840(orf name)|uniprotkb:SGCE(gene name)|psi-mi:SGCE(display_short)|uniprotkb:ESG(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311702|imex:IM-17664-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001092870.1|refseq:NP_001092871.1|refseq:NP_003910.1|ensembl:ENST00000445866|ensembl:ENSP00000398930|ensembl:ENST00000642933|ensembl:ENSP00000496237|ensembl:ENSP00000497130|refseq:NP_001288068.1|ensembl:ENSG00000127990(gene)|ensembl:ENST00000648936(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0032590"(dendrite membrane)|go:"GO:0042383"(sarcolemma)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR030775|entrezgene/locuslink:BC021709(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:rqhN7Niu1cyD+1hN6xE/ApmAqFU9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:344AB5C68B215521|rigid:XeM1kK1ARF5HiHnQMdja1mc2afc false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q8IW00 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311759|uniprotkb:B4DNI6|uniprotkb:Q96MX7|ensembl:ENSP00000331062 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:vstm4_human(display_long)|uniprotkb:VSTM4(gene name)|psi-mi:VSTM4(display_short)|uniprotkb:C10orf72(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311758|imex:IM-17664-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001026916.2|refseq:NP_659421.1|ensembl:ENSG00000165633(gene)|ensembl:ENST00000332853(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|entrezgene/locuslink:NM_001031746(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:TyzZ1xzwJfdLOCsHR3DkSWr/32A9606 intact-crc:94501B9DB8832FF5|rigid:B0xLC6e8NZhXWc6ie/QfZuZYO8E false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q86VG3 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-3923037|uniprotkb:Q96DD6|uniprotkb:D3DR18|ensembl:ENSP00000334848|ensembl:ENSP00000403937|ensembl:ENSP00000431374|ensembl:ENSP00000432685|ensembl:ENSP00000433407|ensembl:ENSP00000483671|ensembl:ENSP00000503448|ensembl:ENSP00000504720 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:iftap_human(display_long)|uniprotkb:IFTAP(gene name)|psi-mi:IFTAP(display_short)|uniprotkb:C11orf74(gene name synonym)|uniprotkb:NWC(gene name synonym)|uniprotkb:Protein HEPIS(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311781|imex:IM-17664-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) ensembl:ENST00000678060(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007340"(acrosome reaction)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|interpro:IPR040028|mint:Q86VG3|ensembl:ENST00000676979(transcript)|refseq:XP_011518187.1|refseq:NP_620142.2|refseq:NP_001263651.1|refseq:NP_001263652.1|refseq:NP_001263653.1|refseq:NP_001263654.1|refseq:NP_001263655.1|refseq:NP_001263656.1|ensembl:ENSG00000166352(gene)|ensembl:ENST00000334307(transcript)|ensembl:ENST00000446510(transcript)|ensembl:ENST00000530697(transcript)|ensembl:ENST00000531554(transcript)|ensembl:ENST00000532470(transcript)|ensembl:ENST00000617650(transcript)|refseq:XP_006718201.1|entrezgene/locuslink:NM_138787(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:oLcIB5xXVb7erU+hZ8Bgt//y/4A9606 intact-crc:855B97566E9A3598|rigid:XienDo7H/mY5t8Hwn4mLTWqyGFM false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q5VZQ5 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311748|uniprotkb:Q0P5T8|ensembl:ENSP00000357811 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:tex36_human(display_long)|uniprotkb:TEX36(gene name)|psi-mi:TEX36(display_short)|uniprotkb:C10orf122(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311753|imex:IM-17664-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001121674.1|refseq:NP_001305062.1|ensembl:ENSG00000175018(gene)|ensembl:ENST00000368821(transcript)|interpro:IPR029369|entrezgene/locuslink:BC062717(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:VAqaBFPkJtsGUI/udOdW0a17Gs09606 intact-crc:D467343880DF25C7|rigid:ADWXbUe9rBgkWS2TxcstZbPDffM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q13595 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-2685506|uniprotkb:B4DUA9|uniprotkb:B4DQI6|uniprotkb:E9PD75|ensembl:ENSP00000297071 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:tra2a_human(display_long)|uniprotkb:Transformer-2 protein homolog A(gene name synonym)|uniprotkb:TRA2A(gene name)|psi-mi:TRA2A(display_short) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311734|imex:IM-17664-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001269686.1|refseq:NP_001269687.1|refseq:NP_001269688.1|refseq:XP_005249782.1|refseq:NP_037425.1|refseq:XP_016867578.1|refseq:XP_016867579.1|ensembl:ENSG00000164548(gene)|ensembl:ENST00000297071(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q13595|entrezgene/locuslink:NM_013293(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:JvcdzipB7mCy8eV3z8TaVjucLLM9606 intact-crc:8884EC848B8ED764|rigid:zreLNbXYp5RvIShUfo7AmbZfcV0 false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q3B726 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-1642554|uniprotkb:A0PJ45|uniprotkb:B7Z724|ensembl:ENSP00000222567 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:rpa43_human(display_long)|uniprotkb:POLR1F(gene name)|psi-mi:POLR1F(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit F(gene name synonym)|uniprotkb:TWISTNB(gene name synonym)|uniprotkb:Twist neighbor protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311741|imex:IM-17664-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001002926.1|ensembl:ENSG00000105849(gene)|ensembl:ENST00000222567(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005736"(RNA polymerase I complex)|interpro:IPR036898|interpro:IPR041178|interpro:IPR041901|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|entrezgene/locuslink:NM_001002926(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:Dh5USsPRiE7XJFM90H43I/IzodY9606 intact-crc:AF3BD42B580092DB|rigid:YzfmjxwoTodUsnpbjSJtjw9tOsU false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q7Z5V6 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311770|imex:IM-17664-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410|entrezgene/locuslink:NM_145017(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 intact-crc:2F5DAE39D96AC627|rigid:pJ47IC2Fqd8aU4HMlGNOxY3+OUU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H0A9 uniprotkb:P36873-2 intact:EBI-372911|uniprotkb:Q52LS9|uniprotkb:Q6FIH5|uniprotkb:Q6P0L3|uniprotkb:Q9NSE5|uniprotkb:B4E323|ensembl:ENSP00000291672|ensembl:ENSP00000483544 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:spc1l_human(display_long)|uniprotkb:SPATC1L(gene name)|psi-mi:SPATC1L(display_short)|uniprotkb:C21orf56(gene name synonym)|uniprotkb:Spermatogenesis and centriole-associated protein 1-like protein(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311800|imex:IM-17664-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001136326.1|refseq:NP_115637.3|refseq:XP_005261245.1|ensembl:ENSG00000160284(gene)|ensembl:ENSG00000274679(gene)|ensembl:ENST00000291672(transcript)|ensembl:ENST00000621926(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0097224"(sperm connecting piece)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR026715|interpro:IPR029384|interpro:IPR029385|refseq:XP_016883969.1|entrezgene/locuslink:BC084577(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:XmhTBFFSm1zvQTYpxTZq9JRRi9c9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:A4A829C05151FE7A|rigid:/pVZhjKGptHNlo2g0Lme5oDo/ro false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-4311818 uniprotkb:P36873-2 entrezgene/locuslink:AL833488 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:dkfzp686i1129(display_short)|psi-mi:EBI-4311818(display_long) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311817|imex:IM-17664-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:AL833488(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - no-uniprot-update: - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 - rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:E59F9B7DA831B43F false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TAP8 uniprotkb:P36873-2 intact:EBI-4311445|uniprotkb:A4D2C5|intact:EBI-28969042|ensembl:ENSP00000292330 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:ppr35_human(display_long)|uniprotkb:PPP1R35(gene name)|psi-mi:PPP1R35(display_short)|uniprotkb:C7orf47(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311807|imex:IM-17664-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659467.1|ensembl:ENSP00000292330|ensembl:ENSG00000160813(gene)|ensembl:ENST00000292330(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|interpro:IPR029135|interpro:IPR033590|entrezgene/locuslink:NM_145030(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:2P9EODxUIbPGxtH3r0zMNU2IXtI9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:A7A0269FE0EAF1A5|rigid:pskWlgIIaEO6XUMV3/xw7leyKak false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6PJW8 uniprotkb:P36873-2 intact:EBI-750390|uniprotkb:Q5VSY9|uniprotkb:Q5VTM7|uniprotkb:Q8IYA9|uniprotkb:Q8N3L5|uniprotkb:Q8NB09|uniprotkb:Q8TEI2|uniprotkb:Q96MR5|ensembl:ENSP00000355470 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:cnst_human(display_long)|uniprotkb:CNST(gene name)|psi-mi:CNST(display_short)|uniprotkb:C1orf71(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311795|imex:IM-17664-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001132931.1|refseq:NP_689822.2|refseq:XP_005273138.2|refseq:XP_011542412.1|refseq:XP_011542413.1|ensembl:ENSG00000162852(gene)|ensembl:ENST00000366513(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071253"(connexin binding)|interpro:IPR028129|interpro:IPR042318|go:"GO:0019902"(phosphatase binding)|entrezgene/locuslink:NM_152609(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:N60V+qHcb7zp0PVzK1VerUEsrLg9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:B014C169557F14C4|rigid:CoLFV3ItnvKvoKVmuGR42gdONN8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q5SZB4 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311456|uniprotkb:Q8NA65|uniprotkb:Q2M1I2|ensembl:ENSP00000361556 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:ci050_human(display_long)|uniprotkb:C9orf50(gene name)|psi-mi:C9orf50(display_short) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311812|imex:IM-17664-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_955382.3|ensembl:ENSG00000179058(gene)|ensembl:ENST00000372478(transcript)|interpro:IPR032756|refseq:XP_011516957.1|refseq:XP_011516958.1|entrezgene/locuslink:NM_199350(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:KiEzRlUJMgGUSIvEGuL0P7Y8XUo9606 intact-crc:056D1D935B30009B|rigid:Zh+G7brno16ycvuF4l5/jpBKW7Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H0I2 uniprotkb:P36873-2 intact:EBI-744099|uniprotkb:Q6UWD7|ensembl:ENSP00000243878 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:enkd1_human(display_long)|uniprotkb:ENKD1(gene name)|psi-mi:ENKD1(display_short)|uniprotkb:C16orf48(gene name synonym)|uniprotkb:UNQ6410/PRO21183(orf name) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311788|imex:IM-17664-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115516.1|ensembl:ENSG00000124074(gene)|ensembl:ENST00000243878(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0097546"(ciliary base)|interpro:IPR027012|interpro:IPR027710|mint:Q9H0I2|entrezgene/locuslink:NM_032140(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:kLnlpnGpF+sgQ+umqiN1CIK/7wc9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:C0DB9E4A399A8B57|rigid:d+rG3XbkUT0QcEhHpxEgE16eNhY false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q6ZMZ0 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311848|imex:IM-17664-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1|entrezgene/locuslink:BC062374(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 intact-crc:E1C5A6D27E46038D|rigid:iCrwPfQREh4U+XnzIKDIjfnSFqw false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q8TEC5 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-2130111|uniprotkb:A8K961|uniprotkb:Q08AM9|uniprotkb:Q6GMR9|uniprotkb:Q8N5S8|uniprotkb:Q96LP8|ensembl:ENSP00000352028|ensembl:ENSP00000424497 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:sh3r2_human(display_long)|uniprotkb:POSH-eliminating RING protein(gene name synonym)|uniprotkb:POSH3(gene name synonym)|uniprotkb:POSHER(gene name synonym)|uniprotkb:SH3RF2(gene name)|psi-mi:SH3RF2(display_short)|uniprotkb:Heart protein phosphatase 1-binding protein(gene name synonym)|uniprotkb:PPP1R39(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 39(gene name synonym)|uniprotkb:RING finger protein 158(gene name synonym)|uniprotkb:RNF158(gene name synonym)|uniprotkb:SH3 domain-containing RING finger protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SH3RF2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311868|imex:IM-17664-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:XP_011535871.1|refseq:NP_689763.3|refseq:XP_016864625.1|refseq:XP_006714820.1|ensembl:ENSG00000156463(gene)|ensembl:ENST00000359120(transcript)|ensembl:ENST00000511217(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR028511|interpro:IPR035792|interpro:IPR035794|interpro:IPR035822|interpro:IPR036028|entrezgene/locuslink:BC073914(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:ipP8ZHmrTHHf+77eHJSoHFA45449606 intact-crc:1174423796B4CFE0|rigid:LAGdUVwcloeglA3qIsCeZZrrc6s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17028 uniprotkb:P36873-2 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311827|imex:IM-17664-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|entrezgene/locuslink:AK021966(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:5A312B5E51248535|rigid:NbD4BXREgjaog7BnVBvaORjXWno false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HBL0 uniprotkb:P36873-2 intact:EBI-3389814|uniprotkb:Q6IPI5|ensembl:ENSP00000171887|uniprotkb:Q4ZG71 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:tens1_human(display_long)|uniprotkb:TNS1(gene name)|psi-mi:TNS1(display_short)|uniprotkb:TNS(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311841|imex:IM-17664-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079308(gene)|ensembl:ENST00000171887(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR033929|interpro:IPR035012|interpro:IPR035892|interpro:IPR036860|go:"GO:0003779"(actin binding)|refseq:NP_001294951.1|refseq:NP_072174.3|dip:DIP-60948N|entrezgene/locuslink:BC063142(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:xyE5fHGhuORnau3rX2Nfpi1LCvg9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:80C5009089DD662A|rigid:ix94I6wk5qllQVD1e72YDKtozjw false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q9NPI7 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-2805442|uniprotkb:Q3B7J7|ensembl:ENSP00000340083|ensembl:ENSP00000499834 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:krcc1_human(display_long)|uniprotkb:CHBP2(gene name synonym)|uniprotkb:Cryptogenic hepatitis-binding protein 2(gene name synonym)|uniprotkb:BM-003(orf name)|uniprotkb:BM-044(orf name)|uniprotkb:KRCC1(gene name)|psi-mi:KRCC1(display_short) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311834|imex:IM-17664-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001291455.1|ensembl:ENSG00000172086(gene)|ensembl:ENST00000347055(transcript)|mint:Q9NPI7|ensembl:ENST00000672766(transcript)|refseq:NP_057702.1|refseq:XP_016859781.1|dip:DIP-58940N|entrezgene/locuslink:NM_016618(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:XhDNDZRzRP0oVJgkmgn4CrnQObQ9606 intact-crc:2A968EBFE17E78FD|rigid:h+OjaSl5H46rrwR0oxEvkTShDn4 false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q9NRG7 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311855|uniprotkb:Q6ZW71|uniprotkb:Q9BVQ3|ensembl:ENSP00000382327 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:d39u1_human(display_long)|uniprotkb:SDR39U1(gene name)|psi-mi:SDR39U1(display_short)|uniprotkb:C14orf124(gene name synonym)|uniprotkb:HCDI(gene name synonym)|uniprotkb:Short-chain dehydrogenase/reductase family 39U member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311861|imex:IM-17664-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_064580.2|refseq:NP_001277221.1|refseq:NP_001295004.1|ensembl:ENST00000399395(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR010099(Conserved hypothetical protein, YfcH)|interpro:IPR013549(Region of unknown function DUF1731)|interpro:IPR036291|rcsb pdb:4B4O|ensembl:ENSG00000100445(gene)|entrezgene/locuslink:BC000989(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2019/02/20 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:vhowOi3rrKZnmbK1cnr+JgAzqpg9606 intact-crc:29D520D994FFB5F2|rigid:GVnNElLp0DiGrk7MtctoUDNSFdM false sufficient binding region:299-337 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q6ZMY3 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311874|uniprotkb:Q24JU3|uniprotkb:Q96LN6|uniprotkb:Q8N869|uniprotkb:Q8NBC6|uniprotkb:Q6PI90|uniprotkb:Q8N8U0|ensembl:ENSP00000353670 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:spoc1_human(display_long)|uniprotkb:SPOCD1(gene name)|psi-mi:SPOCD1(display_short) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311873|imex:IM-17664-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_653170.3|refseq:XP_011540715.1|refseq:XP_011540716.1|refseq:NP_001268916.1|refseq:NP_001268917.1|ensembl:ENST00000360482(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|ensembl:ENSG00000134668(gene)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR036575|entrezgene/locuslink:NM_144569(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:ZT8INLIl0a2msutHwYhZ99FURuE9606 intact-crc:6A99FC969C7C73E3|rigid:3tMY63i3Nyjp1cVxXPKAvELK1Z4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N5T2 uniprotkb:P36873-2 intact:EBI-1221022|uniprotkb:Q9NUX1|uniprotkb:B9A6M0|ensembl:ENSP00000264866 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:tbc19_human(display_long)|uniprotkb:TBC1D19(gene name)|psi-mi:TBC1D19(display_short) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311889|imex:IM-17664-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060787.2|refseq:NP_001278983.1|ensembl:ENSG00000109680(gene)|ensembl:ENST00000264866(transcript)|go:"GO:0005096"(GTPase activator activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|interpro:IPR042507|entrezgene/locuslink:NM_018317(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:m+8uxdwUOMyQxYFhehFfV/7w6rc9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:003C5D4CE2A59B39|rigid:2CdaKYvONkz0H18dhsNS0pCLTwY false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-4311896 uniprotkb:P36873-2 entrezgene/locuslink:AY726579 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:testis809(display_short)|psi-mi:EBI-4311896(display_long) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311899|imex:IM-17664-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) entrezgene/locuslink:AY726579(identity) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - no-uniprot-update: - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 - rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:B1291FD421E1BFAC false - sufficient binding region:299-337 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q9UKC9 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-724253|ensembl:ENSP00000417601|uniprotkb:Q6IAN3|uniprotkb:Q9Y3Y9|uniprotkb:Q9NVQ8|uniprotkb:Q9UK27|uniprotkb:Q9UKA5|uniprotkb:B4DQV0|uniprotkb:E9PD06 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:fbxl2_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 2(gene name synonym)|uniprotkb:F-box protein FBL2/FBL3(gene name synonym)|uniprotkb:FBXL2(gene name)|psi-mi:FBXL2(display_short)|uniprotkb:FBL2(gene name synonym)|uniprotkb:FBL3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4311924|imex:IM-17664-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) ensembl:ENSG00000153558(gene)|ensembl:ENST00000484457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|interpro:IPR001611(Leucine-rich repeat)|refseq:NP_001165184.1|refseq:NP_036289.3|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|rcsb pdb:6O60|entrezgene/locuslink:AC122176(identity) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:BkHs0ftn8BdTq/UmoduZueg5C649606 intact-crc:4840F00E33387459|rigid:gv/Vv+XQqww9T4F2GiDXXeZR4fc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36873-2 uniprotkb:Q7Z5V6 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264434|imex:IM-17664-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 intact-crc:03BBAA34B3B8BD9E|rigid:pJ47IC2Fqd8aU4HMlGNOxY3+OUU false necessary binding region:299-337 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z5V6 uniprotkb:P36873-2 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6265516|imex:IM-17664-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410 intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:A55BDD0B0C762660|rigid:pJ47IC2Fqd8aU4HMlGNOxY3+OUU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96S59 uniprotkb:P36873-1 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264422|imex:IM-17664-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:D534D7A289EE19A0|rigid:JM+YvfBZjPHlaXzBQh54pqlN3wY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36873-1 uniprotkb:Q7Z5V6 intact:EBI-356289|ensembl:ENSP00000335084 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264418|imex:IM-17664-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 intact-crc:2F89541B2534AE63|rigid:dEcr53apddB1AvlTjTkDMzAU93s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A1DRY3 uniprotkb:P36873-1 intact:EBI-4311408 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:a1dry3_human(display_long) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264414|imex:IM-17664-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR018247|interpro:IPR036770|refseq:NP_001287902.1 ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:oXf5vAP1LTlQ7fMiR/iYKYhqcT09606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:4EA22B30997FD310|rigid:li+1s682RJg5keilw4sZaK6p9ok false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5JR98 uniprotkb:P36873-1 intact:EBI-4311709|ensembl:ENSP00000341803|ensembl:ENSP00000501642 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:dylt4_human(display_long)|uniprotkb:DYNLT4(gene name)|psi-mi:DYNLT4(display_short)|uniprotkb:Protein N22.1(gene name synonym)|uniprotkb:TCTEX1D4(gene name synonym)|uniprotkb:Tctex-2-beta(gene name synonym)|uniprotkb:Tctex1 domain-containing protein 4(gene name synonym) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264410|imex:IM-17664-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013654.1|refseq:XP_011539677.1|refseq:XP_011539678.1|ensembl:ENSG00000188396(gene)|ensembl:ENST00000339355(transcript)|ensembl:ENST00000675259(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005930"(axoneme)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR005334(Tctex-1)|interpro:IPR038586 ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:pfp60a4xhJsvZKmjtuzxuYYMi4k9606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:86EF3346F58CC8B5|rigid:mJs7mLGBukGLSAd13P2Zb/ReMJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36873-2 uniprotkb:Q5JR98 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311709|ensembl:ENSP00000341803|ensembl:ENSP00000501642 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:dylt4_human(display_long)|uniprotkb:DYNLT4(gene name)|psi-mi:DYNLT4(display_short)|uniprotkb:Protein N22.1(gene name synonym)|uniprotkb:TCTEX1D4(gene name synonym)|uniprotkb:Tctex-2-beta(gene name synonym)|uniprotkb:Tctex1 domain-containing protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264426|imex:IM-17664-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_001013654.1|refseq:XP_011539677.1|refseq:XP_011539678.1|ensembl:ENSG00000188396(gene)|ensembl:ENST00000339355(transcript)|ensembl:ENST00000675259(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005930"(axoneme)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR005334(Tctex-1)|interpro:IPR038586 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:pfp60a4xhJsvZKmjtuzxuYYMi4k9606 intact-crc:AADDCD696300DB48|rigid:fgWrkBAxJO3zFVbO8ZSKiqt+uYs false necessary binding region:299-337 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36873-2 uniprotkb:A1DRY3 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-4311408 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:a1dry3_human(display_long) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264430|imex:IM-17664-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR018247|interpro:IPR036770|refseq:NP_001287902.1 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:oXf5vAP1LTlQ7fMiR/iYKYhqcT09606 intact-crc:0C00343024EE7180|rigid:/qZLGw1EK+INra5YROjx/i70id0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96S59 uniprotkb:P36873-2 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264438|imex:IM-17664-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:F906298D1F620A5D|rigid:mWcen83XCqOvAI4BgSwEgxbIdWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SWA1 uniprotkb:P36873-1 intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156 intact:EBI-356289|ensembl:ENSP00000335084 psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short) psi-mi:p36873-1(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:Gamma-1(isoform synonym)|uniprotkb:PPPCC1(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264406|imex:IM-17664-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000158615(gene)|ensembl:ENST00000367188(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR019512|interpro:IPR019523|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|go:"GO:0034976"(response to endoplasmic reticulum stress) ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|intact:EBI-356283(pp1g_human) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:EBWZBipo2XhGvdskPjJVlLSo5T89606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:3BCFBF308A44CCF9|rigid:ipKP+KfL1II+vYOhAMzrr7zEwU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36873-2 uniprotkb:Q96S59 intact:EBI-3964623|ensembl:ENSP00000341779 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6265526|imex:IM-17664-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 intact-crc:F4CC6DA1C9B21B6C|rigid:mWcen83XCqOvAI4BgSwEgxbIdWM false necessary binding region:299-337 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62136 uniprotkb:Q96S59 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264632|imex:IM-17664-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 intact-crc:4FFEF7087152F02E|rigid:7AgkpctHSP+qQtkaVrD2xHL0wpY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62136 uniprotkb:Q5JR98 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 intact:EBI-4311709|ensembl:ENSP00000341803|ensembl:ENSP00000501642 psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:dylt4_human(display_long)|uniprotkb:DYNLT4(gene name)|psi-mi:DYNLT4(display_short)|uniprotkb:Protein N22.1(gene name synonym)|uniprotkb:TCTEX1D4(gene name synonym)|uniprotkb:Tctex-2-beta(gene name synonym)|uniprotkb:Tctex1 domain-containing protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264645|imex:IM-17664-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) refseq:NP_001013654.1|refseq:XP_011539677.1|refseq:XP_011539678.1|ensembl:ENSG00000188396(gene)|ensembl:ENST00000339355(transcript)|ensembl:ENST00000675259(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005930"(axoneme)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR005334(Tctex-1)|interpro:IPR038586 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rogid:pfp60a4xhJsvZKmjtuzxuYYMi4k9606 intact-crc:1C2513EC0D30213B|rigid:v/f5FKgcNK+XKJNjfkdOrWBBcYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62136 uniprotkb:Q7Z5V6 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264637|imex:IM-17664-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410 - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 intact-crc:B54374B1DD8847ED|rigid:pwGBuKMt2lfdcbLEbGK4ehFZMkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A1DRY3 uniprotkb:P62136 intact:EBI-4311408 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:a1dry3_human(display_long) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264641|imex:IM-17664-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR018247|interpro:IPR036770|refseq:NP_001287902.1 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:oXf5vAP1LTlQ7fMiR/iYKYhqcT09606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 intact-crc:0DE0E21FCC2F72F8|rigid:Bg1cSbvP+hepz7rpbFHmfQKuXOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5JR98 uniprotkb:P36873-2 intact:EBI-4311709|ensembl:ENSP00000341803|ensembl:ENSP00000501642 intact:EBI-3964623|ensembl:ENSP00000341779 psi-mi:dylt4_human(display_long)|uniprotkb:DYNLT4(gene name)|psi-mi:DYNLT4(display_short)|uniprotkb:Protein N22.1(gene name synonym)|uniprotkb:TCTEX1D4(gene name synonym)|uniprotkb:Tctex-2-beta(gene name synonym)|uniprotkb:Tctex1 domain-containing protein 4(gene name synonym) psi-mi:p36873-2(display_long)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Gamma-2(isoform synonym)|uniprotkb:PPPCC2(isoform synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6265522|imex:IM-17664-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013654.1|refseq:XP_011539677.1|refseq:XP_011539678.1|ensembl:ENSG00000188396(gene)|ensembl:ENST00000339355(transcript)|ensembl:ENST00000675259(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005930"(axoneme)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR005334(Tctex-1)|interpro:IPR038586 intact:EBI-356283(isoform-parent)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000340766(transcript)|uniprotkb:P36873-2(isoform-parent) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:pfp60a4xhJsvZKmjtuzxuYYMi4k9606 rogid:zMWoSUfhkPeRJUfTO+Jb/VMVTGc9606 intact-crc:E25A6036AC2C4251|rigid:fgWrkBAxJO3zFVbO8ZSKiqt+uYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SWA1 uniprotkb:P62136 intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fardilha et al. (2011) pubmed:21382349|imex:IM-17664 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6264649|imex:IM-17664-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000158615(gene)|ensembl:ENST00000367188(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR019512|interpro:IPR019523|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|go:"GO:0034976"(response to endoplasmic reticulum stress) refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/07/28 2014/10/16 rogid:EBWZBipo2XhGvdskPjJVlLSo5T89606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 intact-crc:A1059F9A72F82577|rigid:rYUe6GQQ8DAi+bk+i10Q8PgG2ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)