#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Z0R4 uniprotkb:A6X8Z5 intact:EBI-645386|uniprotkb:Q9R143|uniprotkb:F8VQE5|ensembl:ENSMUSP00000109635 intact:EBI-4325995|uniprotkb:Q3TL91|uniprotkb:Q3U1T7|uniprotkb:Q3UDE7|uniprotkb:Q3UUH4|uniprotkb:Q6ZPW0|uniprotkb:Q9WV94|ensembl:ENSMUSP00000023487 psi-mi:itsn1_mouse(display_long)|uniprotkb:EH and SH3 domains protein 1(gene name synonym)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short)|uniprotkb:Ese1(gene name synonym)|uniprotkb:Itsn(gene name synonym) psi-mi:rhg31_mouse(display_long)|uniprotkb:Arhgap31(gene name)|psi-mi:Arhgap31(display_short)|uniprotkb:Cdgap(gene name synonym)|uniprotkb:Kiaa1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym) psi-mi:"MI:0096"(pull down) Primeau et al. (2011) pubmed:21349274|imex:IM-16900|mint:MINT-8094043 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4326020|imex:IM-16900-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103745.1|refseq:NP_034717.2|ensembl:ENSMUSG00000022957(gene)|ensembl:ENSMUST00000114002(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q9Z0R4|rcsb pdb:3HS8|rcsb pdb:3JV3|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013408 refseq:NP_064656.2|ensembl:ENSMUSG00000022799(gene)|ensembl:ENSMUST00000023487(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149 - - - figure legend:Figure 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/10 2014/10/16 rogid:naFu4D6P1S+/t5+VVVeb0De8lEg10090 rogid:cke6zTbYFfVm5W0qMGbjV0IrqvM10090 intact-crc:88F74EC479175F51|rigid:9usX90U+WAOEmzHA6BTUHNGUvP0 false glutathione s tranferase tag:?-?|sufficient binding region:1070-1131 35s radiolabel:?-?|sufficient binding region:1-515 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q9Z0R4 uniprotkb:A6X8Z5 intact:EBI-645386|uniprotkb:Q9R143|uniprotkb:F8VQE5|ensembl:ENSMUSP00000109635 intact:EBI-4325995|uniprotkb:Q3TL91|uniprotkb:Q3U1T7|uniprotkb:Q3UDE7|uniprotkb:Q3UUH4|uniprotkb:Q6ZPW0|uniprotkb:Q9WV94|ensembl:ENSMUSP00000023487 psi-mi:itsn1_mouse(display_long)|uniprotkb:EH and SH3 domains protein 1(gene name synonym)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short)|uniprotkb:Ese1(gene name synonym)|uniprotkb:Itsn(gene name synonym) psi-mi:rhg31_mouse(display_long)|uniprotkb:Arhgap31(gene name)|psi-mi:Arhgap31(display_short)|uniprotkb:Cdgap(gene name synonym)|uniprotkb:Kiaa1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym) psi-mi:"MI:0096"(pull down) Primeau et al. (2011) pubmed:21349274|imex:IM-16900|mint:MINT-8094043 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4326061|imex:IM-16900-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103745.1|refseq:NP_034717.2|ensembl:ENSMUSG00000022957(gene)|ensembl:ENSMUST00000114002(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q9Z0R4|rcsb pdb:3HS8|rcsb pdb:3JV3|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013408 refseq:NP_064656.2|ensembl:ENSMUSG00000022799(gene)|ensembl:ENSMUST00000023487(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149 - - - figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/10 2014/10/16 rogid:naFu4D6P1S+/t5+VVVeb0De8lEg10090 rogid:cke6zTbYFfVm5W0qMGbjV0IrqvM10090 intact-crc:2AF97E2700802070|rigid:9usX90U+WAOEmzHA6BTUHNGUvP0 false sufficient binding region:1070-1131|glutathione s tranferase tag:?-? necessary binding region:181-358|mutation decreasing interaction:291-291,292-292,293-293|mutation disrupting interaction:297-297,299-299,300-300|mutation decreasing interaction:302-302,303-303|mutation decreasing interaction:304-304,305-305,307-307|mutation decreasing interaction:313-313,314-314,315-315,316-316,317-317,318-318|myc tag:?-?|mutation decreasing interaction:301-301|mutation decreasing interaction:309-309 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q640N3 uniprotkb:Q9Z0R4 intact:EBI-4326075|uniprotkb:E9QKX0|uniprotkb:Q571I5 intact:EBI-645386|uniprotkb:Q9R143|uniprotkb:F8VQE5|ensembl:ENSMUSP00000109635 psi-mi:rhg30_mouse(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym) psi-mi:itsn1_mouse(display_long)|uniprotkb:EH and SH3 domains protein 1(gene name synonym)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short)|uniprotkb:Ese1(gene name synonym)|uniprotkb:Itsn(gene name synonym) psi-mi:"MI:0096"(pull down) Primeau et al. (2011) pubmed:21349274|imex:IM-16900|mint:MINT-8094043 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4326092|imex:IM-16900-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005508.2|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013420 refseq:NP_001103745.1|refseq:NP_034717.2|ensembl:ENSMUSG00000022957(gene)|ensembl:ENSMUST00000114002(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q9Z0R4|rcsb pdb:3HS8|rcsb pdb:3JV3|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013408 - - - figure legend:Figure 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/10 2014/10/16 rogid:6ThouE4dmXi8MQuZ6odULeofha010090 rogid:naFu4D6P1S+/t5+VVVeb0De8lEg10090 intact-crc:CE953DC9401ED08B|rigid:yr++z4sYSLOI5i82yK/BkJOiql0 false necessary binding region:1-334|myc tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:1070-1131 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Z0R4 uniprotkb:A6X8Z5 intact:EBI-645386|uniprotkb:Q9R143|uniprotkb:F8VQE5|ensembl:ENSMUSP00000109635 intact:EBI-4325995|uniprotkb:Q3TL91|uniprotkb:Q3U1T7|uniprotkb:Q3UDE7|uniprotkb:Q3UUH4|uniprotkb:Q6ZPW0|uniprotkb:Q9WV94|ensembl:ENSMUSP00000023487 psi-mi:itsn1_mouse(display_long)|uniprotkb:EH and SH3 domains protein 1(gene name synonym)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short)|uniprotkb:Ese1(gene name synonym)|uniprotkb:Itsn(gene name synonym) psi-mi:rhg31_mouse(display_long)|uniprotkb:Arhgap31(gene name)|psi-mi:Arhgap31(display_short)|uniprotkb:Cdgap(gene name synonym)|uniprotkb:Kiaa1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym) psi-mi:"MI:0049"(filter binding) Primeau et al. (2011) pubmed:21349274|imex:IM-16900|mint:MINT-8094043 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4398732|imex:IM-16900-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103745.1|refseq:NP_034717.2|ensembl:ENSMUSG00000022957(gene)|ensembl:ENSMUST00000114002(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q9Z0R4|rcsb pdb:3HS8|rcsb pdb:3JV3|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416482|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013408 refseq:NP_064656.2|ensembl:ENSMUSG00000022799(gene)|ensembl:ENSMUST00000023487(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149 - - - figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/10 2014/10/16 rogid:naFu4D6P1S+/t5+VVVeb0De8lEg10090 rogid:cke6zTbYFfVm5W0qMGbjV0IrqvM10090 intact-crc:79B81AFE0BD93C9C|rigid:9usX90U+WAOEmzHA6BTUHNGUvP0 false - sufficient binding region:284-333 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)