#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BX09 uniprotkb:Q99LT0 intact:EBI-1556543|uniprotkb:Q3TBL4|uniprotkb:Q6PAP0|uniprotkb:Q6PFC2|uniprotkb:Q3U3G1|ensembl:ENSMUSP00000141003 intact:EBI-3843922|ensembl:ENSMUSP00000108190|ensembl:ENSMUSP00000126702|ensembl:ENSMUSP00000156795|ensembl:ENSMUSP00000156830 psi-mi:rbbp5_mouse(display_long)|uniprotkb:Rbbp5(gene name)|psi-mi:Rbbp5(display_short) psi-mi:dpy30_mouse(display_long)|uniprotkb:Dpy30(gene name)|psi-mi:Dpy30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jiang et al. (2011) pubmed:21335234|imex:IM-15744 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843921|imex:IM-15744-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766105.2|dip:DIP-61809N|ensembl:ENSMUSG00000026439(gene)|ensembl:ENSMUST00000190997(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q8BX09|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459|reactome:R-MMU-8951664|go:"GO:0035097"(histone methyltransferase complex) refseq:NP_001139694.1|refseq:NP_001139695.1|refseq:NP_001139696.1|refseq:NP_077746.3|dip:DIP-61810N|ensembl:ENSMUSG00000024067(gene)|ensembl:ENSMUST00000112571(transcript)|ensembl:ENSMUST00000164832(transcript)|ensembl:ENSMUST00000232687(transcript)|ensembl:ENSMUST00000233581(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q99LT0|reactome:R-MMU-3214841|reactome:R-MMU-8936459 psi-mi:"MI:0469"(intact) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/03/21 2014/10/16 rogid:IfmUqzNWpYZzHDMDGeLiZqEcRK010090 rogid:mDxCDIA2qGNoPtuHJgm5w4Spu5k10090 intact-crc:78B10A6F47500612|rigid:dII73Mqc/qQ/wnnnnC79K67hwYE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BX09 uniprotkb:P55200 intact:EBI-1556543|uniprotkb:Q3TBL4|uniprotkb:Q6PAP0|uniprotkb:Q6PFC2|uniprotkb:Q3U3G1|ensembl:ENSMUSP00000141003 intact:EBI-3843925|uniprotkb:E9QNE7|uniprotkb:Q3UEU1|uniprotkb:Q3USE7|ensembl:ENSMUSP00000110337 psi-mi:rbbp5_mouse(display_long)|uniprotkb:Rbbp5(gene name)|psi-mi:Rbbp5(display_short) psi-mi:kmt2a_mouse(display_long)|uniprotkb:Kmt2a(gene name)|psi-mi:Kmt2a(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:All1(gene name synonym)|uniprotkb:Hrx(gene name synonym)|uniprotkb:Mll(gene name synonym)|uniprotkb:Mll1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jiang et al. (2011) pubmed:21335234|imex:IM-15744 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843921|imex:IM-15744-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766105.2|dip:DIP-61809N|ensembl:ENSMUSG00000026439(gene)|ensembl:ENSMUST00000190997(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q8BX09|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459|reactome:R-MMU-8951664|go:"GO:0035097"(histone methyltransferase complex) refseq:NP_001074518.1|dip:DIP-58597N|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|ensembl:ENSMUSG00000002028(gene)|ensembl:ENSMUST00000114689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035864"(response to potassium ion)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048536"(spleen development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050890"(cognition)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1901674"(regulation of histone H3-K27 acetylation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|reactome:R-MMU-3214841|reactome:R-MMU-8936459|reactome:R-MMU-8939236 psi-mi:"MI:0469"(intact) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/03/21 2014/10/16 rogid:IfmUqzNWpYZzHDMDGeLiZqEcRK010090 rogid:LMM70ilCyOvuc7xip92jlnD7yE810090 intact-crc:78B10A6F47500612|rigid:dII73Mqc/qQ/wnnnnC79K67hwYE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BX09 uniprotkb:Q91X20 intact:EBI-1556543|uniprotkb:Q3TBL4|uniprotkb:Q6PAP0|uniprotkb:Q6PFC2|uniprotkb:Q3U3G1|ensembl:ENSMUSP00000141003 intact:EBI-1556554|uniprotkb:Q3UIF9|uniprotkb:Q9Z2X4|ensembl:ENSMUSP00000070957 psi-mi:rbbp5_mouse(display_long)|uniprotkb:Rbbp5(gene name)|psi-mi:Rbbp5(display_short) psi-mi:ash2l_mouse(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:Ash2l(gene name)|psi-mi:Ash2l(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jiang et al. (2011) pubmed:21335234|imex:IM-15744 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843921|imex:IM-15744-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766105.2|dip:DIP-61809N|ensembl:ENSMUSG00000026439(gene)|ensembl:ENSMUST00000190997(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q8BX09|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459|reactome:R-MMU-8951664|go:"GO:0035097"(histone methyltransferase complex) refseq:NP_035921.2|dip:DIP-39161N|ensembl:ENSMUSG00000031575(gene)|ensembl:ENSMUST00000068892(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048096"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q91X20|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459 psi-mi:"MI:0469"(intact) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/03/21 2014/10/16 rogid:IfmUqzNWpYZzHDMDGeLiZqEcRK010090 rogid:3ub+DLUG8tmHIoZHh9j8/bHHMWY10090 intact-crc:78B10A6F47500612|rigid:dII73Mqc/qQ/wnnnnC79K67hwYE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BX09 uniprotkb:P61965 intact:EBI-1556543|uniprotkb:Q3TBL4|uniprotkb:Q6PAP0|uniprotkb:Q6PFC2|uniprotkb:Q3U3G1|ensembl:ENSMUSP00000141003 intact:EBI-1247084|uniprotkb:Q91VA5|uniprotkb:Q922C9|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|ensembl:ENSMUSP00000109585 psi-mi:rbbp5_mouse(display_long)|uniprotkb:Rbbp5(gene name)|psi-mi:Rbbp5(display_short) psi-mi:wdr5_mouse(display_long)|uniprotkb:Wdr5(gene name)|psi-mi:Wdr5(display_short)|uniprotkb:Big(gene name synonym)|uniprotkb:Big3(gene name synonym)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WD repeat-containing protein BIG-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jiang et al. (2011) pubmed:21335234|imex:IM-15744 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843921|imex:IM-15744-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766105.2|dip:DIP-61809N|ensembl:ENSMUSG00000026439(gene)|ensembl:ENSMUST00000190997(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q8BX09|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459|reactome:R-MMU-8951664|go:"GO:0035097"(histone methyltransferase complex) refseq:NP_543124.1|refseq:XP_006497735.1|dip:DIP-38618N|ensembl:ENSMUSG00000026917(gene)|ensembl:ENSMUST00000113952(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61965|rcsb pdb:2XL2|rcsb pdb:2XL3|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-8936459|reactome:R-MMU-8951664 psi-mi:"MI:0469"(intact) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2011/03/21 2014/10/16 rogid:IfmUqzNWpYZzHDMDGeLiZqEcRK010090 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU10090 intact-crc:78B10A6F47500612|rigid:dII73Mqc/qQ/wnnnnC79K67hwYE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)