#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35550 uniprotkb:P97304 intact:EBI-7817407|ensembl:ENSMUSP00000037613|intact:MINT-1854224|uniprotkb:Q99L58 intact:EBI-8459958|intact:MINT-4133004|ensembl:ENSMUSP00000058355 psi-mi:fbrl_mouse(display_long)|uniprotkb:Fbl(gene name)|psi-mi:Fbl(display_short)|uniprotkb:Nucleolar protein 1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:rpac2_mouse(display_long)|uniprotkb:Polr1d(gene name)|psi-mi:Polr1d(display_short)|uniprotkb:Rpo1-3(gene name synonym)|uniprotkb:AC19(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit D(gene name synonym)|uniprotkb:RNA polymerase I 16 kDa subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Denissov et al. (2011) mint:MINT-8151531|pubmed:21331097|imex:IM-15375|doi:10.1038/embor.2011.8 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8595729|mint:MINT-8151536|imex:IM-15375-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016074"("sno(s)RNA metabolic process")|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P35550|reactome:R-MMU-6791226|go:"GO:0001652"(granular component)|ensembl:ENSMUSG00000046865(gene)|ensembl:ENSMUST00000042405(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|refseq:NP_032017.2|mint:MINT-8151538(identity) refseq:NP_033113.1|ensembl:ENSMUSG00000029642(gene)|ensembl:ENSMUST00000050970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603|mint:P97304|mint:MINT-8151539(identity) go:"GO:0005730"(nucleolus) function:Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA|comment:mint|comment:homomint function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively|comment:mint comment:homomint|comment:mint|figure legend:f3e sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2011/03/31 2014/10/16 rogid:+sPcLBU2pW5qt05z4awAKpVQryY10090 rogid:34qgzc4fm0rbf5MGhIGw65DpkVI10090 intact-crc:3FA75AE39AABD189|rigid:VjaztAMeQ9TwGUMLbSM+K6g06f0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)