#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-8580945 intact:EBI-8580951 intact:MINT-8149294 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:chain b(display_short)|psi-mi:EBI-8580945(display_long) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0114"(x-ray crystallography) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8580932|mint:MINT-8149130|imex:IM-15359-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:325053920(uniprot-removed-ac)|mint:MINT-8149132(identity) mint:MINT-8149135(identity) - comment:mint|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:mint|no-uniprot-update: figure legend:F2 T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2021/02/11 - - intact-crc:7D8900F37EF8CD62 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8580945 intact:EBI-8580940 intact:MINT-8149294 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:chain b(display_short)|psi-mi:EBI-8580945(display_long) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0114"(x-ray crystallography) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8580932|mint:MINT-8149130|imex:IM-15359-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:325053920(uniprot-removed-ac)|mint:MINT-8149132(identity) mint:MINT-8149134(identity) - comment:mint|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:mint|no-uniprot-update: figure legend:F2 T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2021/02/11 - - intact-crc:7D8900F37EF8CD62 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8580945 uniprotkb:P01903 intact:MINT-8149294 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 psi-mi:chain b(display_short)|psi-mi:EBI-8580945(display_long) psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8580932|mint:MINT-8149130|imex:IM-15359-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:325053920(uniprot-removed-ac)|mint:MINT-8149132(identity) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149133(identity) - comment:mint|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:F2 T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2021/02/11 - rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 intact-crc:7D8900F37EF8CD62 false - maltose binding protein tag:?-?(MINT-8149141)|binding-associated region:26-207(MINT-8150294) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8580983|mint:MINT-8149351|imex:IM-15359-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149353(identity) mint:MINT-8149359(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.5x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:8A2D4C13E62B3160 false maltose binding protein tag:?-?(MINT-8149354) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8580983|mint:MINT-8149351|imex:IM-15359-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149353(identity) mint:MINT-8149357(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.5x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:8A2D4C13E62B3160 false maltose binding protein tag:?-?(MINT-8149354) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581030|mint:MINT-8149372|imex:IM-15359-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149375(identity) mint:MINT-8149379(identity) - - comment:mint|no-uniprot-update: figure legend:F1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.2x10^-7(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:F6FFA0F966EEF29D false maltose binding protein tag:?-?(MINT-8149376) mutation increasing interaction:29-29(MINT-8149385) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581030|mint:MINT-8149372|imex:IM-15359-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149375(identity) mint:MINT-8149381(identity) - - comment:mint|no-uniprot-update: figure legend:F1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.2x10^-7(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:F6FFA0F966EEF29D false maltose binding protein tag:?-?(MINT-8149376) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581053|mint:MINT-8149389|imex:IM-15359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149392(identity) mint:MINT-8149400(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.0x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:1553EE3EAACDEFA4 false maltose binding protein tag:?-?(MINT-8149393) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581053|mint:MINT-8149389|imex:IM-15359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149392(identity) mint:MINT-8149396(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.0x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:1553EE3EAACDEFA4 false maltose binding protein tag:?-?(MINT-8149393) mutation decreasing interaction:50-50(MINT-8149397) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581076|mint:MINT-8149407|imex:IM-15359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149410(identity) mint:MINT-8149418(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.8x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:2FCD6F032380315F false maltose binding protein tag:?-?(MINT-8149411) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581076|mint:MINT-8149407|imex:IM-15359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149410(identity) mint:MINT-8149414(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.8x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:2FCD6F032380315F false maltose binding protein tag:?-?(MINT-8149411) mutation decreasing interaction:55-56(MINT-8149415) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581099|mint:MINT-8149429|imex:IM-15359-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149432(identity) mint:MINT-8149440(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.0x10^-4(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:3FFBDF727C56EA45 false maltose binding protein tag:?-?(MINT-8149433) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581099|mint:MINT-8149429|imex:IM-15359-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149432(identity) mint:MINT-8149436(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.0x10^-4(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:3FFBDF727C56EA45 false maltose binding protein tag:?-?(MINT-8149433) mutation disrupting interaction:98-98(MINT-8149437) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581150|mint:MINT-8149447|imex:IM-15359-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149450(identity) mint:MINT-8149458(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.0x10^-4(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:9261897ABFF05DB7 false maltose binding protein tag:?-?(MINT-8149451) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581150|mint:MINT-8149447|imex:IM-15359-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149450(identity) mint:MINT-8149454(identity) - - comment:mint|no-uniprot-update: comment:homomint|comment:mint|figure legend:F1h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.0x10^-4(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:9261897ABFF05DB7 false maltose binding protein tag:?-?(MINT-8149451) mutation disrupting interaction:100-100(MINT-8149455) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580940 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053922|intact:MINT-8149290 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain d(display_short)|psi-mi:EBI-8580940(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581173|mint:MINT-8149465|imex:IM-15359-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149468(identity) mint:MINT-8149472(identity) - - comment:mint|no-uniprot-update: figure legend:F1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.0x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:A16304A59EF18490 false maltose binding protein tag:?-?(MINT-8149469) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01903 intact:EBI-8580951 intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287 genbank_protein_gi:325053921|intact:MINT-8149292 psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym) psi-mi:chain c(display_short)|psi-mi:EBI-8580951(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Yin et al. (2011) mint:MINT-8149124|pubmed:21297580|imex:IM-15359|doi:10.1038/emboj.2011.21 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8581173|mint:MINT-8149465|imex:IM-15359-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N|mint:MINT-8149468(identity) mint:MINT-8149476(identity) - - comment:mint|no-uniprot-update: figure legend:F1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.0x10^-6(molar) 2011/03/21 2021/02/11 rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606 - intact-crc:A16304A59EF18490 false maltose binding protein tag:?-?(MINT-8149469) mutation decreasing interaction:96-96(MINT-8149481) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)