#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38713 uniprotkb:P40075 intact:EBI-12630|uniprotkb:D3DL23|ensemblfungi:YHR073W intact:EBI-16735|ensemblfungi:YER120W|uniprotkb:D3DM26 psi-mi:osh3_yeast(display_long)|uniprotkb:YHR073W(locus name)|uniprotkb:OSH3(gene name)|psi-mi:OSH3(display_short) psi-mi:scs2_yeast(display_long)|uniprotkb:YER120W(locus name)|uniprotkb:SCS2(gene name)|psi-mi:SCS2(display_short)|uniprotkb:VAP homolog 1(gene name synonym)|uniprotkb:Choline sensitivity suppressor protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843675|imex:IM-15773-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR073W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|ensemblfungi:YHR073W(gene)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036598|interpro:IPR037239|interpro:IPR041680|rcsb pdb:4IAP|rcsb pdb:4IC4|rcsb pdb:4INQ|reactome:R-SCE-192105|go:"GO:0035621"(ER to Golgi ceramide transport)|refseq:NP_011940.1|sgd:S000001115|mint:P38713|dip:DIP-2148N refseq:NP_011046.3|ensemblfungi:YER120W(gene)|ensemblfungi:YER120W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0006348"|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032377"(regulation of intracellular lipid transport)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|rcsb pdb:6LP4|reactome:R-SCE-6798695|reactome:R-SCE-9609523|sgd:S000000922|dip:DIP-2272N|mint:P40075 psi-mi:"MI:0469"(intact) crc64:B1AD1210EFFB9AFE crc64:45390E24E31D392E figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2014/10/16 rogid:fhlpdXizvjnmxMYAM+Z/6AYPT4Y559292 rogid:P5Pirj7wRxTi5bdoNs8lCzzTNPI559292 intact-crc:660211E6CF1D00EC|rigid:ixhzUY0S7HYJL5QF4Q0QW6FfTjo false glutathione s tranferase tag:?-?|sufficient binding region:1-613 ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) chebi:"CHEBI:18348" uniprotkb:P35844 intact:EBI-1257123 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate(display_short)|psi-mi:"CHEBI:18348"(display_long) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0049"(filter binding) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3843772|imex:IM-15773-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 - - - figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2014/10/16 - rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:D4EF410701503D08 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) chebi:"CHEBI:17283" uniprotkb:P35844 intact:EBI-1257113 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0049"(filter binding) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3843751|imex:IM-15773-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 - - - figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2014/10/16 - rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:F08092F39C8C06FF false - his tag:?-?|mutation disrupting interaction:236-236,242-243 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) chebi:"CHEBI:17526" uniprotkb:P35844 intact:EBI-2465282 intact:EBI-9648|ensemblfungi:YPL145C|uniprotkb:D6W3M4|uniprotkb:E9P8U8 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:kes1_yeast(display_long)|uniprotkb:KES1(gene name)|psi-mi:KES1(display_short)|uniprotkb:OSH4(gene name synonym)|uniprotkb:Protein KES1(gene name synonym)|uniprotkb:LPI3C(orf name)|uniprotkb:P2614(orf name)|uniprotkb:YPL145C(locus name) psi-mi:"MI:0049"(filter binding) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3843763|imex:IM-15773-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensemblfungi:YPL145C(gene)|ensemblfungi:YPL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:1ZHT|rcsb pdb:1ZHW|rcsb pdb:1ZHX|rcsb pdb:1ZHY|rcsb pdb:1ZHZ|rcsb pdb:1ZI7|rcsb pdb:3SPW|rcsb pdb:4F4B|rcsb pdb:4FES|rcsb pdb:4JCH|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_015180.1|sgd:S000006066|dip:DIP-2867N|mint:P35844 - - - figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2014/10/16 - rogid:6vsHrA4RScGr2+xmii0wiuvK1OM559292 intact-crc:D4247099315B64FD false - his tag:?-?|mutation disrupting interaction:236-236,242-243 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32368 uniprotkb:P38713 intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1 intact:EBI-12630|uniprotkb:D3DL23|ensemblfungi:YHR073W psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym) psi-mi:osh3_yeast(display_long)|uniprotkb:YHR073W(locus name)|uniprotkb:OSH3(gene name)|psi-mi:OSH3(display_short) psi-mi:"MI:0030"(cross-linking study) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843795|imex:IM-15773-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368 ensemblfungi:YHR073W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|ensemblfungi:YHR073W(gene)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036598|interpro:IPR037239|interpro:IPR041680|rcsb pdb:4IAP|rcsb pdb:4IC4|rcsb pdb:4INQ|reactome:R-SCE-192105|go:"GO:0035621"(ER to Golgi ceramide transport)|refseq:NP_011940.1|sgd:S000001115|mint:P38713|dip:DIP-2148N psi-mi:"MI:0469"(intact) crc64:73DB1FA163BC17AE crc64:B1AD1210EFFB9AFE figure legend:Supp. Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/21 2014/10/16 rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292 rogid:fhlpdXizvjnmxMYAM+Z/6AYPT4Y559292 intact-crc:24EDA1D11B6A6A82|rigid:tq+CU0p4AvP5H6oh9qg2ubFmgmE false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32368 uniprotkb:P32368 intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1 intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1 psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym) psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843804|imex:IM-15773-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368 ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368 psi-mi:"MI:0469"(intact) crc64:73DB1FA163BC17AE crc64:73DB1FA163BC17AE figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/21 2014/10/16 rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292 rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292 intact-crc:B60A02BE9EAD26CB|rigid:WFoYrNhaJTQ6TgleONEDEzoo92M false myc tag:?-? myc tag:?-? - 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38713 uniprotkb:P32368 intact:EBI-12630|uniprotkb:D3DL23|ensemblfungi:YHR073W intact:EBI-16210|ensemblfungi:YKL212W|uniprotkb:D6VWZ1 psi-mi:osh3_yeast(display_long)|uniprotkb:YHR073W(locus name)|uniprotkb:OSH3(gene name)|psi-mi:OSH3(display_short) psi-mi:sac1_yeast(display_long)|uniprotkb:SAC1(gene name)|psi-mi:SAC1(display_short)|uniprotkb:RSD1(gene name synonym)|uniprotkb:YKL212W(locus name)|uniprotkb:Recessive suppressor of secretory defect(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Stefan et al. (2011) pubmed:21295699|imex:IM-15773 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3843873|imex:IM-15773-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR073W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|ensemblfungi:YHR073W(gene)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036598|interpro:IPR037239|interpro:IPR041680|rcsb pdb:4IAP|rcsb pdb:4IC4|rcsb pdb:4INQ|reactome:R-SCE-192105|go:"GO:0035621"(ER to Golgi ceramide transport)|refseq:NP_011940.1|sgd:S000001115|mint:P38713|dip:DIP-2148N ensemblfungi:YKL212W(gene)|ensemblfungi:YKL212W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035339"(SPOTS complex)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0072517"(host cell viral assembly compartment)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:3LWT|rcsb pdb:4TU3|reactome:R-SCE-1483248|reactome:R-SCE-1660514|reactome:R-SCE-1660516|refseq:NP_012710.1|sgd:S000001695|dip:DIP-6610N|mint:P32368 psi-mi:"MI:0469"(intact) crc64:B1AD1210EFFB9AFE crc64:73DB1FA163BC17AE figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/21 2014/10/16 rogid:fhlpdXizvjnmxMYAM+Z/6AYPT4Y559292 rogid:MjUsiA11tbe6dHMnFscX13x3gCM559292 intact-crc:59E3A1207758426E|rigid:tq+CU0p4AvP5H6oh9qg2ubFmgmE false sufficient binding region:588-996|glutathione s tranferase tag:?-? fluorescent dye label:341-341|sufficient binding region:1-522|mutation:392-392,395-395 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)