#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9WVE0	uniprotkb:Q7TQK4	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-3835564|uniprotkb:Q9CV81|uniprotkb:Q9CVW2|ensembl:ENSMUSP00000030003	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos3_mouse(display_long)|uniprotkb:Exosc3(gene name)|psi-mi:Exosc3(display_short)|uniprotkb:Rrp40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835756|imex:IM-15741-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_079789.1|ensembl:ENSMUSG00000028322(gene)|ensembl:ENSMUST00000030003(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q7TQK4|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2B|agonist:anti-CD40, IL-4, and TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-b-cell lymphoma)|taxid:10090(Mus musculus B-cell lymphoma)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:9dQOdl5oJfHDn1xwahKg4BQba9Y10090	intact-crc:379D47574E149C13|rigid:VXeafBRvG2Vpp8DdluMAGRP4okc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q8BTW3	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-3835562|uniprotkb:Q9CSR7|ensembl:ENSMUSP00000147696	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos6_mouse(display_long)|uniprotkb:Exosc6(gene name)|psi-mi:Exosc6(display_short)|uniprotkb:Mtr3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835756|imex:IM-15741-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_082550.1|ensembl:ENSMUSG00000109941(gene)|ensembl:ENSMUST00000210390(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q8BTW3|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2B|agonist:anti-CD40, IL-4, and TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-b-cell lymphoma)|taxid:10090(Mus musculus B-cell lymphoma)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:T1m4+ZV2a+vpfBOaDD8qU5cZ85c10090	intact-crc:379D47574E149C13|rigid:VXeafBRvG2Vpp8DdluMAGRP4okc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q9CRA8	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-644704|uniprotkb:Q8K1J2|ensembl:ENSMUSP00000078580|ensembl:ENSMUSP00000145948	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos5_mouse(display_long)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:Exosc5(gene name)|psi-mi:Exosc5(display_short)|uniprotkb:D7Wsu180e(gene name synonym)|uniprotkb:Rrp46(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835756|imex:IM-15741-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_613052.1|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226|reactome:R-MMU-429958|ensembl:ENSMUSG00000061286(gene)|ensembl:ENSMUST00000079634(transcript)|ensembl:ENSMUST00000206561(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9CRA8	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2B|agonist:anti-CD40, IL-4, and TGF-beta|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-b-cell lymphoma)|taxid:10090(Mus musculus B-cell lymphoma)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:aLlaVFp6XM+O6L9hOkdqXKo/NwY10090	intact-crc:379D47574E149C13|rigid:VXeafBRvG2Vpp8DdluMAGRP4okc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GZX7	uniprotkb:Q9Y3B2	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q15024	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q96B26	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:y/cReHiPMubzNruyETohBjbRick9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q5RKV6	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-2841747|ensembl:ENSP00000398597	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q9NQT5	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q13868	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q9NQT4	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q9NPD3	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371823|ensembl:ENSP00000315476	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834330|imex:IM-15741-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	intact-crc:1982B86464DE3C02|rigid:QXS0QpmWXxukfSdnGHcNhvo1c3o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZX7	uniprotkb:Q9NQT5	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835956|imex:IM-15741-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:B2DB2D82379064AF|rigid:gdSLqvJRWIu5/oONHsLMQWLZ10c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GZX7	uniprotkb:Q9NQT4	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835956|imex:IM-15741-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	intact-crc:B2DB2D82379064AF|rigid:gdSLqvJRWIu5/oONHsLMQWLZ10c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GZX7	uniprotkb:Q5RKV6	intact:EBI-3834328|uniprotkb:Q8NFC1|uniprotkb:Q6QJ81|ensembl:ENSP00000229335	intact:EBI-2841747|ensembl:ENSP00000398597	psi-mi:aicda_human(display_long)|uniprotkb:AICDA(gene name)|psi-mi:AICDA(display_short)|uniprotkb:AID(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835956|imex:IM-15741-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065712.1|dip:DIP-48519N|ensembl:ENSG00000111732(gene)|ensembl:ENST00000229335(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:5JJ4|rcsb pdb:5W0R|rcsb pdb:5W0U|rcsb pdb:5W0Z|rcsb pdb:5W1C|refseq:NP_001317272.1	refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma)	-	2011/03/14	2014/10/16	rogid:iYm2M2vkaVmMGCSpC1KG6potARw9606	rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606	intact-crc:B2DB2D82379064AF|rigid:gdSLqvJRWIu5/oONHsLMQWLZ10c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q9CRA8	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-644704|uniprotkb:Q8K1J2|ensembl:ENSMUSP00000078580|ensembl:ENSMUSP00000145948	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos5_mouse(display_long)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:Exosc5(gene name)|psi-mi:Exosc5(display_short)|uniprotkb:D7Wsu180e(gene name synonym)|uniprotkb:Rrp46(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835566|imex:IM-15741-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_613052.1|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226|reactome:R-MMU-429958|ensembl:ENSMUSG00000061286(gene)|ensembl:ENSMUST00000079634(transcript)|ensembl:ENSMUST00000206561(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9CRA8	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-b-cell)|taxid:10090(Mus musculus B-cell)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:aLlaVFp6XM+O6L9hOkdqXKo/NwY10090	intact-crc:255A0B04811CF7BE|rigid:VXeafBRvG2Vpp8DdluMAGRP4okc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q7TQK4	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-3835564|uniprotkb:Q9CV81|uniprotkb:Q9CVW2|ensembl:ENSMUSP00000030003	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos3_mouse(display_long)|uniprotkb:Exosc3(gene name)|psi-mi:Exosc3(display_short)|uniprotkb:Rrp40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835566|imex:IM-15741-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_079789.1|ensembl:ENSMUSG00000028322(gene)|ensembl:ENSMUST00000030003(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q7TQK4|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-b-cell)|taxid:10090(Mus musculus B-cell)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:9dQOdl5oJfHDn1xwahKg4BQba9Y10090	intact-crc:255A0B04811CF7BE|rigid:VXeafBRvG2Vpp8DdluMAGRP4okc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q8BTW3	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-3835562|uniprotkb:Q9CSR7|ensembl:ENSMUSP00000147696	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos6_mouse(display_long)|uniprotkb:Exosc6(gene name)|psi-mi:Exosc6(display_short)|uniprotkb:Mtr3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3835566|imex:IM-15741-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_082550.1|ensembl:ENSMUSG00000109941(gene)|ensembl:ENSMUST00000210390(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q8BTW3|reactome:R-MMU-429958|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-450604|reactome:R-MMU-6791226	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-b-cell)|taxid:10090(Mus musculus B-cell)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:T1m4+ZV2a+vpfBOaDD8qU5cZ85c10090	intact-crc:255A0B04811CF7BE|rigid:VXeafBRvG2Vpp8DdluMAGRP4okc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2L1	uniprotkb:Q9NQT5	intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842258|imex:IM-15741-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520(gene)|ensembl:ENST00000377767(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:729897EBE194ABEE|rigid:D+dhwT52XMLGZ6B9o8VLhbVJciw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2L1	uniprotkb:Q01780	intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842258|imex:IM-15741-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520(gene)|ensembl:ENST00000377767(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:729897EBE194ABEE|rigid:D+dhwT52XMLGZ6B9o8VLhbVJciw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2L1	uniprotkb:Q9WVE0	intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842258|imex:IM-15741-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520(gene)|ensembl:ENST00000377767(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:729897EBE194ABEE|rigid:D+dhwT52XMLGZ6B9o8VLhbVJciw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQT5	uniprotkb:Q9NQT5	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842185|imex:IM-15741-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:EB34B84427ED1CBB|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQT5	uniprotkb:Q9WVE0	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842185|imex:IM-15741-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:EB34B84427ED1CBB|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQT5	uniprotkb:Q01780	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842185|imex:IM-15741-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:EB34B84427ED1CBB|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQT4	uniprotkb:Q01780	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842160|imex:IM-15741-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:9B37BFDD92883CCF|rigid:A/EwiNW+kCuVcMKh91OXBjpPgDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQT4	uniprotkb:Q9NQT5	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842160|imex:IM-15741-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:9B37BFDD92883CCF|rigid:A/EwiNW+kCuVcMKh91OXBjpPgDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQT4	uniprotkb:Q9WVE0	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842160|imex:IM-15741-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:9B37BFDD92883CCF|rigid:A/EwiNW+kCuVcMKh91OXBjpPgDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13868	uniprotkb:Q9NQT5	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842150|imex:IM-15741-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:97E98035E7EAFA1C|rigid:KYgv2xF5wPOtaJ6FgRE0uCOD5Xg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13868	uniprotkb:Q9WVE0	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842150|imex:IM-15741-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:97E98035E7EAFA1C|rigid:KYgv2xF5wPOtaJ6FgRE0uCOD5Xg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13868	uniprotkb:Q01780	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842150|imex:IM-15741-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:97E98035E7EAFA1C|rigid:KYgv2xF5wPOtaJ6FgRE0uCOD5Xg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3B2	uniprotkb:Q9NQT5	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842142|imex:IM-15741-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:892653CF20FBA792|rigid:17R1OsnDapF3Mw0p+nOvjupvLjk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3B2	uniprotkb:Q01780	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842142|imex:IM-15741-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:892653CF20FBA792|rigid:17R1OsnDapF3Mw0p+nOvjupvLjk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3B2	uniprotkb:Q9WVE0	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842142|imex:IM-15741-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:892653CF20FBA792|rigid:17R1OsnDapF3Mw0p+nOvjupvLjk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5RKV6	uniprotkb:Q01780	intact:EBI-2841747|ensembl:ENSP00000398597	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842193|imex:IM-15741-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:8C56CD505D66F8A7|rigid:/GgJhMUfxH41vvnAc6wpw3SbG1s	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5RKV6	uniprotkb:Q9NQT5	intact:EBI-2841747|ensembl:ENSP00000398597	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842193|imex:IM-15741-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:8C56CD505D66F8A7|rigid:/GgJhMUfxH41vvnAc6wpw3SbG1s	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5RKV6	uniprotkb:Q9WVE0	intact:EBI-2841747|ensembl:ENSP00000398597	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842193|imex:IM-15741-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:8C56CD505D66F8A7|rigid:/GgJhMUfxH41vvnAc6wpw3SbG1s	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15024	uniprotkb:Q01780	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842207|imex:IM-15741-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:649C0437039C318B|rigid:Pbiv7BpYT5jopNqObb52uGs1YGI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15024	uniprotkb:Q9NQT5	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842207|imex:IM-15741-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:649C0437039C318B|rigid:Pbiv7BpYT5jopNqObb52uGs1YGI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15024	uniprotkb:Q9WVE0	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842207|imex:IM-15741-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:649C0437039C318B|rigid:Pbiv7BpYT5jopNqObb52uGs1YGI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96B26	uniprotkb:Q9WVE0	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842222|imex:IM-15741-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:56776CACBB86356F|rigid:q6S46nsMuoWBNlF48wtBGz4bKgI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96B26	uniprotkb:Q01780	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842222|imex:IM-15741-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:56776CACBB86356F|rigid:q6S46nsMuoWBNlF48wtBGz4bKgI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96B26	uniprotkb:Q9NQT5	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842222|imex:IM-15741-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:56776CACBB86356F|rigid:q6S46nsMuoWBNlF48wtBGz4bKgI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q9NQT5	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842249|imex:IM-15741-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:905C6D03582459C6|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WVE0	uniprotkb:Q01780	intact:EBI-3835567|ensembl:ENSMUSP00000040524	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842249|imex:IM-15741-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:905C6D03582459C6|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NPD3	uniprotkb:Q9NQT5	intact:EBI-371823|ensembl:ENSP00000315476	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842171|imex:IM-15741-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:BB06D3AE9CEA426E|rigid:uaEr0dgkl7huQdmWVqG5OyiIv94	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NPD3	uniprotkb:Q9WVE0	intact:EBI-371823|ensembl:ENSP00000315476	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842171|imex:IM-15741-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:BB06D3AE9CEA426E|rigid:uaEr0dgkl7huQdmWVqG5OyiIv94	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NPD3	uniprotkb:Q01780	intact:EBI-371823|ensembl:ENSP00000315476	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842171|imex:IM-15741-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:BB06D3AE9CEA426E|rigid:uaEr0dgkl7huQdmWVqG5OyiIv94	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q01780	uniprotkb:Q01780	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842236|imex:IM-15741-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	intact-crc:C6E88B76A6FEA090|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q01780	uniprotkb:Q9NQT5	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842236|imex:IM-15741-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	intact-crc:C6E88B76A6FEA090|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q01780	uniprotkb:Q9WVE0	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	intact:EBI-3835567|ensembl:ENSMUSP00000040524	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:aicda_mouse(display_long)|uniprotkb:Aicda(gene name)|psi-mi:Aicda(display_short)|uniprotkb:Aid(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)|uniprotkb:Activation-induced cytidine deaminase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Basu et al. (2011)	pubmed:21255825|imex:IM-15741	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3842236|imex:IM-15741-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	refseq:NP_033775.1|dip:DIP-48714N|ensembl:ENSMUSG00000040627(gene)|ensembl:ENSMUST00000043301(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016445"(somatic diversification of immunoglobulins)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080111"(DNA demethylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0051607"(defense response to virus)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/14	2014/10/16	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	rogid:yUGL+YzTA0GGuu11a+tAdDO5BVQ10090	intact-crc:C6E88B76A6FEA090|rigid:eudgGS9jLOG4mpctH2sIb4cXet0	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)