#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O88846 uniprotkb:P61956 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8568724|mint:MINT-8142260|imex:IM-15365-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142262(identity) rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N|mint:MINT-8142263(identity) - comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - comment:homomint|comment:mint|figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:WgudlZhwtQbQInv29BniecTYGY89606 intact-crc:69BD66B16F7BBA54|rigid:CY89F6IRK725vc8eVjzL/71xass false mutation disrupting interaction:51-51(MINT-8142293)|mutation disrupting interaction:50-50(MINT-8142290)|mutation disrupting interaction:71-71(MINT-8142307)|mutation disrupting interaction:42-42(MINT-8142284)|mutation disrupting interaction:63-63(MINT-8142305)|mutation disrupting interaction:72-72(MINT-8142309)|mutation disrupting interaction:40-40(MINT-8142276)|mutation disrupting interaction:74-74(MINT-8142315)|mutation disrupting interaction:73-73(MINT-8142312)|binding-associated region:32-133(MINT-8142269)|mutation disrupting interaction:61-61(MINT-8142299)|mutation disrupting interaction:43-43(MINT-8142287)|mutation disrupting interaction:53-53(MINT-8142296)|mutation disrupting interaction:62-62(MINT-8142302) sumoylated lysine:11-11(MINT-8142273) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O88846 uniprotkb:P61956 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8568871|mint:MINT-8142504|imex:IM-15365-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142506(identity) rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N|mint:MINT-8142536(identity) go:"GO:0005634"(nucleus) comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - comment:homomint|comment:mint|figure legend:f2 sf2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:WgudlZhwtQbQInv29BniecTYGY89606 intact-crc:A92467E09376C6E9|rigid:CY89F6IRK725vc8eVjzL/71xass false binding-associated region:32-133(MINT-8142533)|mutation disrupting interaction:53-53(MINT-8142521)|mutation disrupting interaction:42-42(MINT-8142529)|mutation disrupting interaction:62-62(MINT-8142517)|mutation disrupting interaction:43-43(MINT-8142527)|mutation disrupting interaction:72-72(MINT-8142511)|mutation disrupting interaction:71-71(MINT-8142513)|mutation disrupting interaction:40-40(MINT-8142531)|mutation disrupting interaction:50-50(MINT-8142525)|mutation disrupting interaction:63-63(MINT-8142515)|mutation disrupting interaction:73-73(MINT-8142509)|mutation disrupting interaction:51-51(MINT-8142523)|mutation disrupting interaction:74-74(MINT-8142507)|mutation disrupting interaction:61-61(MINT-8142519) sumoylated lysine:11-11(MINT-8142537) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O88846 uniprotkb:P63165 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8568973|mint:MINT-8142549|imex:IM-15365-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142552(identity) refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N|mint:MINT-8142582(identity) go:"GO:0005634"(nucleus) comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - comment:homomint|comment:mint|figure legend:sf2a sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606 intact-crc:C50CA7BD69A87A8A|rigid:lqIcT2OEZcXhlwFFy2xlrhN+q1E false mutation disrupting interaction:73-73(MINT-8142577)|mutation disrupting interaction:61-61(MINT-8142567)|mutation disrupting interaction:51-51(MINT-8142563)|mutation disrupting interaction:43-43(MINT-8142559)|binding-associated region:32-133(MINT-8142553)|mutation disrupting interaction:74-74(MINT-8142579)|mutation disrupting interaction:71-71(MINT-8142573)|mutation disrupting interaction:50-50(MINT-8142561)|mutation disrupting interaction:40-40(MINT-8142555)|mutation disrupting interaction:72-72(MINT-8142575)|mutation disrupting interaction:53-53(MINT-8142565)|mutation disrupting interaction:42-42(MINT-8142557)|mutation disrupting interaction:63-63(MINT-8142571)|mutation disrupting interaction:62-62(MINT-8142569) sumoylated lysine:?-?(MINT-8142583) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O88846 uniprotkb:Q96T88 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-1548946|uniprotkb:Q8J022|uniprotkb:Q9H6S6|uniprotkb:Q9P115|uniprotkb:Q9P1U7|uniprotkb:A0JBR2|uniprotkb:A8K024|uniprotkb:B2RBA9|uniprotkb:Q2HIX7|ensembl:ENSP00000478348|ensembl:ENSP00000478601|ensembl:ENSP00000484739|ensembl:ENSP00000485604|ensembl:ENSP00000498698 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:uhrf1_human(display_long)|uniprotkb:UHRF1(gene name)|psi-mi:UHRF1(display_short)|uniprotkb:ICBP90(gene name synonym)|uniprotkb:NP95(gene name synonym)|uniprotkb:RNF106(gene name synonym)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 1(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 1(gene name synonym)|uniprotkb:Inverted CCAAT box-binding protein of 90 kDa(gene name synonym)|uniprotkb:Transcription factor ICBP90(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np95(gene name synonym)|uniprotkb:Nuclear protein 95(gene name synonym)|uniprotkb:RING finger protein 106(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF1(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8569067|mint:MINT-8142613|imex:IM-15365-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142615(identity) refseq:NP_001276979.1|refseq:NP_001276980.1|refseq:NP_001276981.1|refseq:NP_037414.3|refseq:NP_001041666.1|ensembl:ENSG00000276043(gene)|ensembl:ENST00000612630(transcript)|ensembl:ENST00000615884(transcript)|ensembl:ENST00000616255(transcript)|ensembl:ENST00000624301(transcript)|ensembl:ENST00000650932(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR000626(Ubiquitin)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|mint:Q96T88|rcsb pdb:2FAZ|rcsb pdb:2L3R|rcsb pdb:2LGG|rcsb pdb:2LGK|rcsb pdb:2LGL|rcsb pdb:2PB7|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3BI7|rcsb pdb:3CLZ|rcsb pdb:3DB3|rcsb pdb:3DB4|rcsb pdb:3DWH|rcsb pdb:3FL2|rcsb pdb:3SHB|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3SOX|rcsb pdb:3T6R|rcsb pdb:3ZVY|rcsb pdb:3ZVZ|rcsb pdb:4GY5|rcsb pdb:4QQD|rcsb pdb:5C6D|rcsb pdb:5IAY|rcsb pdb:5XPI|rcsb pdb:5YY9|rcsb pdb:5YYA|rcsb pdb:6B9M|rcsb pdb:6IIW|rcsb pdb:6VCS|rcsb pdb:6VED|rcsb pdb:6VYJ|rcsb pdb:6W92|reactome:R-HSA-5334118|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-8142621(identity) - comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:AbWLjSoRl82HTcjZlG4DRavDdGc9606 intact-crc:1CE6FB111A3D3E26|rigid:j/Y/mmvkWC06+XxaDFw8/CkEqYk false glutathione s tranferase tag:?-?(MINT-8142616)|binding-associated region:32-133(MINT-8142618) sumoylated lysine:?-?(MINT-8142625) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O88846 uniprotkb:O43290 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8569045|mint:MINT-8142599|imex:IM-15365-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142601(identity) ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N|mint:MINT-8142602(identity) - comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 intact-crc:CCB4BC8EF5CD174F|rigid:Ug/nozPPd+AayZ6dGFtl2jUMHQA false glutathione s tranferase tag:?-?(MINT-8142608)|binding-associated region:32-133(MINT-8142605) sumoylated lysine:?-?(MINT-8142627) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O88846 uniprotkb:P29590 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8569111|mint:MINT-8142643|imex:IM-15365-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142645(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|mint:MINT-8142651(identity) - comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 intact-crc:3DE995A295AEA231|rigid:n+9WvMhhIWuuuSDKZ2XEzW7Rbos false binding-associated region:32-133(MINT-8142646)|glutathione s tranferase tag:?-?(MINT-8142648) sumoylated lysine:?-?(MINT-8142652) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:O88846 uniprotkb:Q13263 intact:EBI-7258907|intact:UNK-5367033|ensembl:ENSRNOP00000019555 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:rnf4_rat(display_long)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:Snurf(gene name synonym)|uniprotkb:Rnf4(gene name)|psi-mi:Rnf4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8569089|mint:MINT-8142629|imex:IM-15365-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008768493.1|refseq:XP_008768494.1|refseq:XP_008768495.1|refseq:NP_062055.1|rgd:3583|ensembl:ENSRNOG00000013930(gene)|ensembl:ENSRNOT00000019555(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0016605"(PML body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|rcsb pdb:3NG2|rcsb pdb:4AP4|rcsb pdb:5AIT|rcsb pdb:5AIU|reactome:R-RNO-983168|refseq:XP_017454634.1|refseq:XP_017454635.1|mint:MINT-8142631(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|mint:MINT-8142637(identity) - comment:mint|function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription - figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2014/10/16 rogid:sxkdS+nFno7SrUQ0BNj5sy+K9IE10116 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:5F8078DF90BF1E32|rigid:wLQ2wqFOwj/lslqjwCeh7gRKgiw false glutathione s tranferase tag:?-?(MINT-8142632)|binding-associated region:32-133(MINT-8142634) sumoylated lysine:?-?(MINT-8142638) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NCN4 uniprotkb:Q96JM3 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU|mint:MINT-8173903(identity)|uniprotkb:Q96JM3(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173906) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q96CB8 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1049156|uniprotkb:Q3B6Z3|uniprotkb:Q9HD71|uniprotkb:B2RC48|ensembl:ENSP00000340737|ensembl:ENSP00000378221|ensembl:ENSP00000415433 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:int12_human(display_long)|uniprotkb:PHD finger protein 22(gene name synonym)|uniprotkb:INTS12(gene name)|psi-mi:INTS12(display_short)|uniprotkb:PHF22(gene name synonym)|uniprotkb:SBBI22(orf name) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001135943.1|refseq:NP_065128.2|refseq:XP_011530445.1|refseq:XP_011530447.1|refseq:XP_005263205.1|ensembl:ENSG00000138785(gene)|ensembl:ENST00000340139(transcript)|ensembl:ENST00000394735(transcript)|ensembl:ENST00000451321(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR039053|interpro:IPR039054|reactome:R-HSA-6807505|dip:DIP-48479N|mint:MINT-8173851(identity)|uniprotkb:Q96CB8(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:zKa0nY59t/jyu7NJBc+y4zKQM1A9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173854) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q5VYK3 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-521451|uniprotkb:O15074|uniprotkb:Q8WU82|ensembl:ENSP00000339889 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:XP_005251907.1|ensembl:ENSG00000136813(gene)|ensembl:ENST00000338205(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043248"(proteasome assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3|mint:MINT-8173935(identity)|uniprotkb:Q5VYK3(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173938) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:O75152 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|mint:MINT-8173891(identity)|uniprotkb:O75152(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173894) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q14739 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N|mint:MINT-8173951(identity)|uniprotkb:Q14739(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173954) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q02809 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-357174|ensembl:ENSP00000196061|uniprotkb:Q96AV9|uniprotkb:Q9H132|uniprotkb:B4DR87|intact:EBI-21357524 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:plod1_human(display_long)|uniprotkb:PLOD(gene name synonym)|uniprotkb:PLOD1(gene name)|psi-mi:PLOD1(display_short)|uniprotkb:LLH(gene name synonym)|uniprotkb:Lysyl hydroxylase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) ensembl:ENSG00000083444(gene)|ensembl:ENST00000196061(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:Q02809|reactome:R-HSA-1650814|refseq:NP_000293.2|refseq:NP_001303249.1|mint:MINT-8173855(identity)|uniprotkb:Q02809(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:q0eJHb8L3qTbN1PnjQ8L0PcpOLw9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173858) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:O94906 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N|mint:MINT-8173919(identity)|uniprotkb:O94906(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173922) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q1KMD3 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1059150|uniprotkb:Q8N3B3|ensembl:ENSP00000301785 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:hnrl2_human(display_long)|uniprotkb:HNRNPUL2(gene name)|psi-mi:HNRNPUL2(display_short)|uniprotkb:HNRPUL2(gene name synonym)|uniprotkb:Scaffold-attachment factor A2(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001073027.1|ensembl:ENSG00000214753(gene)|ensembl:ENST00000301785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q1KMD3|mint:MINT-8173883(identity)|uniprotkb:Q1KMD3(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:TOoq1VTfNNzysqSyPH9MHLbSKPA9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173886) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q8WXI9 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|mint:MINT-8173847(identity)|uniprotkb:Q8WXI9(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173850) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q8IYW5 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-914207|uniprotkb:Q8NA67|uniprotkb:Q96NS4|intact:EBI-28968912|ensembl:ENSP00000320898 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:rn168_human(display_long)|uniprotkb:RNF168(gene name)|psi-mi:RNF168(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF168(gene name synonym)|uniprotkb:RING finger protein 168(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000163961(gene)|ensembl:ENST00000318037(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036351"(histone H2A-K13 ubiquitination)|go:"GO:0036352"(histone H2A-K15 ubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070535"(histone H2A K63-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034725|mint:Q8IYW5|rcsb pdb:3L11|rcsb pdb:4GB0|rcsb pdb:5XIS|rcsb pdb:5XIT|rcsb pdb:5XIU|rcsb pdb:5YDK|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|ensembl:ENSP00000320898|refseq:NP_689830.2|dip:DIP-37451N|mint:MINT-8173871(identity)|uniprotkb:Q8IYW5(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:FTUGOdIMWBYvqjBfeyEsFKJsQtc9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173874) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q5T5X7 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1211496|uniprotkb:A2RRH2|uniprotkb:Q9HCL9|ensembl:ENSP00000358038|ensembl:ENSP00000411268 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:bend3_human(display_long)|uniprotkb:BEND3(gene name)|psi-mi:BEND3(display_short)|uniprotkb:KIAA1553(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:XP_005267136.1|refseq:XP_005267137.1|refseq:NP_001073919.1|refseq:XP_011534307.1|refseq:XP_016866627.1|ensembl:ENSG00000178409(gene)|ensembl:ENST00000369042(transcript)|ensembl:ENST00000429433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000792"(heterochromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1903580"(positive regulation of ATP metabolic process)|interpro:IPR018379|interpro:IPR033583|rcsb pdb:5JNO|mint:MINT-8173879(identity)|uniprotkb:Q5T5X7(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:W+UmsinDpvnD5wV9MZI5YWywK6U9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173882) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q96ST3 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N|mint:MINT-8173943(identity)|uniprotkb:Q96ST3(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173946) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q15269 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-722224|uniprotkb:Q96A77|uniprotkb:B2RAG8|ensembl:ENSP00000291576 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:pwp2_human(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:PWP2H(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_005040.2|refseq:XP_006723973.1|refseq:XP_011507205.1|ensembl:ENSG00000241945(gene)|ensembl:ENST00000291576(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|reactome:R-HSA-6790901|reactome:R-HSA-6791226|mint:MINT-8173911(identity)|uniprotkb:Q15269(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:PYs2LKd3EMjAnp0engZvZn0CeBo9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173914) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q86T24 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2515625|ensembl:ENSP00000314153|ensembl:ENSP00000450969|uniprotkb:Q7Z361|uniprotkb:Q8N3P0|uniprotkb:Q8IVP6|uniprotkb:O00319|uniprotkb:B2R5U6 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:kaiso_human(display_long)|uniprotkb:ZBTB33(gene name)|psi-mi:ZBTB33(display_short)|uniprotkb:KAISO(gene name synonym)|uniprotkb:ZNF348(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 33(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) ensembl:ENSG00000177485(gene)|ensembl:ENST00000326624(transcript)|ensembl:ENST00000557385(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2LT7|rcsb pdb:3FKC|rcsb pdb:3M4T|rcsb pdb:3M8V|rcsb pdb:4F6M|rcsb pdb:4F6N|rcsb pdb:5VMU|rcsb pdb:5VMV|rcsb pdb:5VMW|rcsb pdb:5VMX|rcsb pdb:5VMY|rcsb pdb:5VMZ|rcsb pdb:6DF5|rcsb pdb:6DF8|rcsb pdb:6DF9|rcsb pdb:6DFA|rcsb pdb:6DFB|rcsb pdb:6DFC|rcsb pdb:6V8U|refseq:NP_001171671.1|refseq:NP_006768.1|mint:MINT-8173887(identity)|uniprotkb:Q86T24(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:nD+3FCTCYxUrXZXpBW5Co1V0CHc9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173890) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P78317 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168|mint:MINT-8173907(identity)|uniprotkb:P78317(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173910) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q9UBT2 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N|mint:MINT-8173875(identity)|uniprotkb:Q9UBT2(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173878) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:O43143 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)|mint:MINT-8173867(identity)|uniprotkb:O43143(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173870) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q9NWK9 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2563515|uniprotkb:Q9H278|uniprotkb:Q9NWN0|uniprotkb:B2RBA1|uniprotkb:Q9H3X3|intact:EBI-2686446|uniprotkb:D3DT20|ensembl:ENSP00000359606|uniprotkb:B4DP13 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:bcd1_human(display_long)|uniprotkb:ZNHIT6(gene name)|psi-mi:ZNHIT6(display_short)|uniprotkb:BCD1(gene name synonym)|uniprotkb:C1orf181(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 6(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-75(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_060423.3|ensembl:ENSG00000117174(gene)|ensembl:ENST00000370574(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|refseq:NP_001164141.1|mint:MINT-8173923(identity)|uniprotkb:Q9NWK9(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:4TiEOwp9iKgmO3ytg/GhwvocaiM9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173926) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q2NL82 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-358058|intact:EBI-1048757|intact:EBI-1210739|uniprotkb:Q8WUY5|uniprotkb:Q9NVT0|uniprotkb:Q9P2E6|intact:EBI-2558422|ensembl:ENSP00000301364 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:tsr1_human(display_long)|uniprotkb:TSR1(gene name)|psi-mi:TSR1(display_short)|uniprotkb:KIAA1401(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_060598.3|ensembl:ENSG00000167721(gene)|ensembl:ENST00000301364(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR030387|interpro:IPR039761|mint:Q2NL82|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6ZMT|rcsb pdb:6ZN5|reactome:R-HSA-6791226|mint:MINT-8173955(identity)|uniprotkb:Q2NL82(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:+ZPt5nSRzZbW3tD1IAcdeo5kH309606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173958) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q9H1B7 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2130145|uniprotkb:Q8NDQ2|uniprotkb:Q96JG2|uniprotkb:Q9H3I7|intact:EBI-28987945|ensembl:ENSP00000238647 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:i2bpl_human(display_long)|uniprotkb:IRF2BPL(gene name)|psi-mi:IRF2BPL(display_short)|uniprotkb:C14orf4(gene name synonym)|uniprotkb:KIAA1865(gene name synonym)|uniprotkb:My039(orf name)|uniprotkb:EAP1(gene name synonym)|uniprotkb:Enhanced at puberty protein 1(gene name synonym)|uniprotkb:Interferon regulatory factor 2-binding protein-like(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_078772.1|ensembl:ENSP00000238647|ensembl:ENSG00000119669(gene)|ensembl:ENST00000238647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046543"(development of secondary female sexual characteristics)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR022750|interpro:IPR044882|rcsb pdb:2B9G|rcsb pdb:2CS3|mint:MINT-8173859(identity)|uniprotkb:Q9H1B7(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:Am6HBI/kGwqskhr3163mVz+3Bdk9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173862) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P63165 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N|mint:MINT-8173915(identity)|uniprotkb:P63165(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173918) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P17812 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2|mint:MINT-8173843(identity)|uniprotkb:P17812(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173846) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P05423 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|mint:MINT-8173939(identity)|uniprotkb:P05423(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173942) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q08945 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N|mint:MINT-8173863(identity)|uniprotkb:Q08945(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173866) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P08195 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|mint:MINT-8173899(identity)|uniprotkb:P08195(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173902) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P11586 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3|ensembl:ENSP00000498336|ensembl:ENSP00000498511 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_005947.3|dip:DIP-33682N|ensembl:ENSG00000100714(gene)|ensembl:ENST00000651537(transcript)|ensembl:ENST00000652337(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004477"(methenyltetrahydrofolate cyclohydrolase activity)|go:"GO:0004486"("methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity")|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0009069"(serine family amino acid metabolic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0061053"(somite development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757|mint:MINT-8173927(identity)|uniprotkb:P11586(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173930) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q9HCG8 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-373289|uniprotkb:Q05DC2|uniprotkb:Q4G135|uniprotkb:Q52LF0|uniprotkb:Q6PEX2|uniprotkb:Q7Z6I0|uniprotkb:Q9H5L3|uniprotkb:Q9H6Q6|intact:EBI-2561242|ensembl:ENSP00000387006 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:cwc22_human(display_long)|uniprotkb:CWC22(gene name)|psi-mi:CWC22(display_short)|uniprotkb:fSAPb(gene name synonym)|uniprotkb:KIAA1604(gene name synonym)|uniprotkb:NCM(gene name synonym)|uniprotkb:Nucampholin homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_065994.1|refseq:XP_005246783.1|ensembl:ENSG00000163510(gene)|ensembl:ENST00000410053(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0016607"(nuclear speck)|dip:DIP-31268N|mint:MINT-8173947(identity)|uniprotkb:Q9HCG8(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:LQcs0QFEY4f8ha4jLuOAyz/N5ic9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173950) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:P33991 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N|mint:MINT-8173895(identity)|uniprotkb:P33991(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173898) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q9BW19 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-2107279|uniprotkb:O60887|uniprotkb:Q14834|uniprotkb:Q4KMP0|uniprotkb:Q5SU09|uniprotkb:Q6GMS7|uniprotkb:Q6P4A5|uniprotkb:Q9UQP7|ensembl:ENSP00000363647|ensembl:ENSP00000393963|ensembl:ENSP00000407885 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:kifc1_human(display_long)|uniprotkb:KIFC1(gene name)|psi-mi:KIFC1(display_short)|uniprotkb:HSET(gene name synonym)|uniprotkb:KNSL2(gene name synonym)|uniprotkb:Kinesin-like protein 2(gene name synonym)|uniprotkb:Kinesin-related protein HSET(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_002254.2|ensembl:ENSG00000204197(gene)|ensembl:ENSG00000233450(gene)|ensembl:ENSG00000237649(gene)|ensembl:ENST00000374523(transcript)|ensembl:ENST00000428849(transcript)|ensembl:ENST00000448818(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q9BW19|rcsb pdb:5WDH|reactome:R-HSA-6811434|reactome:R-HSA-983189|mint:MINT-8173839(identity)|uniprotkb:Q9BW19(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:2gWpNwZk9kWJGVvR8xLuDPJYP4M9606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173842) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NCN4 uniprotkb:Q9Y263 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 intact:EBI-1994037|uniprotkb:Q53EU5|uniprotkb:Q5VY33|uniprotkb:Q9NUL8|uniprotkb:Q9NVE9|uniprotkb:Q9UF53|uniprotkb:Q9Y5L1|ensembl:ENSP00000380460 psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:plap_human(display_long)|uniprotkb:PLAA(gene name)|psi-mi:PLAA(display_short)|uniprotkb:PLAP(gene name synonym) psi-mi:"MI:0096"(pull down) Bruderer et al. (2011) mint:MINT-8142188|pubmed:21252943|imex:IM-15365|doi:10.1038/embor.2010.206 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8569133|mint:MINT-8173832|imex:IM-15365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1|mint:MINT-8173833(identity)|uniprotkb:Q8NCN4(original identifier) refseq:NP_001026859.1|ensembl:ENSG00000137055(gene)|ensembl:ENST00000397292(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900045"(negative regulation of protein K63-linked ubiquitination)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013535(PUL)|interpro:IPR015155("PFU (PLAA family ubiquitin binding)")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|interpro:IPR038122|mint:Q9Y263|rcsb pdb:2K89|rcsb pdb:2K8A|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:3EBB|mint:MINT-8173931(identity)|uniprotkb:Q9Y263(original identifier) - - - comment:homomint|comment:mint|figure legend:F3A ST1 SF3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/01 2021/06/18 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rogid:SoClA00UzZpX9vV1cJWvefY6eY89606 intact-crc:96B4EA51777ADCD9|rigid:kvlA+TpzwuARogRSHVGbg4SzwUA false binding-associated region:32-133(MINT-8173836) uncategorized protein modification:?-?(MINT-8173934) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry)