#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O54921	uniprotkb:P11233	intact:EBI-1036795	intact:EBI-1036803|uniprotkb:A4D1W3|ensembl:ENSP00000005257	psi-mi:exoc2_rat(display_long)|uniprotkb:Exoc2(gene name)|psi-mi:Exoc2(display_short)|uniprotkb:Sec5(gene name synonym)|uniprotkb:Sec5l1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:rala_human(display_long)|uniprotkb:RAL(gene name synonym)|uniprotkb:RALA(gene name)|psi-mi:RALA(display_short)	psi-mi:"MI:0096"(pull down)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3507369|imex:IM-15774-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:1UAD|rgd:619961|refseq:NP_599241.2|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029175|reactome:R-RNO-264876|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR039481|reactome:R-RNO-5620916	refseq:NP_005393.2|refseq:XP_006715825.1|go:"GO:0019003"(GDP binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051665"(membrane raft localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:1UAD|rcsb pdb:1ZC3|rcsb pdb:1ZC4|rcsb pdb:2A78|mint:P11233|rcsb pdb:2A9K|rcsb pdb:2BOV|rcsb pdb:6P0I|rcsb pdb:6P0J|rcsb pdb:6P0K|rcsb pdb:6P0L|rcsb pdb:6P0M|rcsb pdb:6P0N|rcsb pdb:6P0O|reactome:R-HSA-1445148|reactome:R-HSA-171007|reactome:R-HSA-8950505|ensembl:ENSG00000006451(gene)|ensembl:ENST00000005257(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|refseq:XP_011513768.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5A|comment:RalA and RalB are GTP-bound|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/01	2014/10/16	rogid:SHbyRkZSRQjpKQefY/EYM9S5yJM10116	rogid:41WF1UoYnYZvwC0OPpYwCEqIg2E9606	intact-crc:94128A6DA7DEA821|rigid:nmXEUFDYad9sG+q8787f8LdTv/c	false	sufficient binding region:1-120|glutathione s tranferase tag:1-120,?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O54921	uniprotkb:P11234	intact:EBI-1036795	intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224	psi-mi:exoc2_rat(display_long)|uniprotkb:Exoc2(gene name)|psi-mi:Exoc2(display_short)|uniprotkb:Sec5(gene name synonym)|uniprotkb:Sec5l1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)	psi-mi:"MI:0096"(pull down)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3507369|imex:IM-15774-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:1UAD|rgd:619961|refseq:NP_599241.2|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029175|reactome:R-RNO-264876|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR039481|reactome:R-RNO-5620916	refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5A|comment:RalA and RalB are GTP-bound|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/01	2014/10/16	rogid:SHbyRkZSRQjpKQefY/EYM9S5yJM10116	rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606	intact-crc:94128A6DA7DEA821|rigid:nmXEUFDYad9sG+q8787f8LdTv/c	false	sufficient binding region:1-120|glutathione s tranferase tag:1-120,?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O54921	uniprotkb:Q14457	intact:EBI-1036795	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:exoc2_rat(display_long)|uniprotkb:Exoc2(gene name)|psi-mi:Exoc2(display_short)|uniprotkb:Sec5(gene name synonym)|uniprotkb:Sec5l1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506830|imex:IM-15774-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:1UAD|rgd:619961|refseq:NP_599241.2|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029175|reactome:R-RNO-264876|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR039481|reactome:R-RNO-5620916	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figs. 4B, 4C, 4F, Supp. Fig. 2A|antagonist:Nutrient starvation|comment:Complex disassembly induced by nutrient starvation was reversed by addition of  non-essential amino acids.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:SHbyRkZSRQjpKQefY/EYM9S5yJM10116	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:7D72423492F24B20|rigid:5UvKw5HvsXqDz8s4yKKuEkLAk9A	false	ha tag:?-?	mutation decreasing interaction:123-123|flag tag:?-?|necessary binding region:88-150	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14457	uniprotkb:Q8IYI6	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506822|imex:IM-15774-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4A, Supp. Figure 2A|agonist:Nutrient starvation|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	intact-crc:AFB785C90F095428|rigid:pVHOEUT3qhH/P9AloLD2XNLqP+E	false	necessary binding region:88-150	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O54921	uniprotkb:Q8CDJ3	intact:EBI-1036795	intact:EBI-3506699|uniprotkb:Q69ZY1|uniprotkb:Q6PFY6|uniprotkb:Q8C6N0|uniprotkb:Q8R3M3|ensembl:ENSMUSP00000039047|ensembl:ENSMUSP00000153718	psi-mi:exoc2_rat(display_long)|uniprotkb:Exoc2(gene name)|psi-mi:Exoc2(display_short)|uniprotkb:Sec5(gene name synonym)|uniprotkb:Sec5l1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:bakor_mouse(display_long)|uniprotkb:Atg14(gene name)|psi-mi:Atg14(display_short)|uniprotkb:D14Ertd436e(gene name synonym)|uniprotkb:Kiaa0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:Atg14L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506742|imex:IM-15774-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:1UAD|rgd:619961|refseq:NP_599241.2|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029175|reactome:R-RNO-264876|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR039481|reactome:R-RNO-5620916	refseq:NP_766187.1|ensembl:ENSMUSG00000037526(gene)|ensembl:ENSMUST00000042988(transcript)|ensembl:ENSMUST00000226299(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|mint:Q8CDJ3|reactome:R-MMU-1632852|dip:DIP-60849N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:SHbyRkZSRQjpKQefY/EYM9S5yJM10116	rogid:Ha+zYY4aNPLZH0LQPz9s1SSK9R410090	intact-crc:A0B4BB51A9D8C094|rigid:42IBNbbI/g7nM+Gtp/8cf2YbOVw	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CDJ3	uniprotkb:Q8IYI6	intact:EBI-3506699|uniprotkb:Q69ZY1|uniprotkb:Q6PFY6|uniprotkb:Q8C6N0|uniprotkb:Q8R3M3|ensembl:ENSMUSP00000039047|ensembl:ENSMUSP00000153718	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	psi-mi:bakor_mouse(display_long)|uniprotkb:Atg14(gene name)|psi-mi:Atg14(display_short)|uniprotkb:D14Ertd436e(gene name synonym)|uniprotkb:Kiaa0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:Atg14L(gene name synonym)	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506734|imex:IM-15774-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_766187.1|ensembl:ENSMUSG00000037526(gene)|ensembl:ENSMUST00000042988(transcript)|ensembl:ENSMUST00000226299(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|mint:Q8CDJ3|reactome:R-MMU-1632852|dip:DIP-60849N	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:Ha+zYY4aNPLZH0LQPz9s1SSK9R410090	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	intact-crc:0FCDE5D0B7B4F841|rigid:MLXxqrUO0zxpt7ALbja+5WJ2Ftc	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O54921	uniprotkb:Q80U62	intact:EBI-1036795	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:exoc2_rat(display_long)|uniprotkb:Exoc2(gene name)|psi-mi:Exoc2(display_short)|uniprotkb:Sec5(gene name synonym)|uniprotkb:Sec5l1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506724|imex:IM-15774-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:1UAD|rgd:619961|refseq:NP_599241.2|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029175|reactome:R-RNO-264876|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR039481|reactome:R-RNO-5620916	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:SHbyRkZSRQjpKQefY/EYM9S5yJM10116	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	intact-crc:810D98FF2A7993E8|rigid:6BWxd+Vi1lok2maaioSsjganjW8	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IYI6	uniprotkb:Q80U62	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506709|imex:IM-15774-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	intact-crc:9033CB1FBFB951E3|rigid:63bs6QNx1EfDASdJgJfkPhaY7sM	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q80U62	uniprotkb:Q9NV70	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506571|imex:IM-15774-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	intact-crc:2077E7E9125B6B31|rigid:gBmk6T5OQrzxF2Fb23W4+685A70	false	flag tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CDJ3	uniprotkb:Q9NV70	intact:EBI-3506699|uniprotkb:Q69ZY1|uniprotkb:Q6PFY6|uniprotkb:Q8C6N0|uniprotkb:Q8R3M3|ensembl:ENSMUSP00000039047|ensembl:ENSMUSP00000153718	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514|ensembl:ENSP00000370695	psi-mi:bakor_mouse(display_long)|uniprotkb:Atg14(gene name)|psi-mi:Atg14(display_short)|uniprotkb:D14Ertd436e(gene name synonym)|uniprotkb:Kiaa0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:Atg14L(gene name synonym)	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506695|imex:IM-15774-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_766187.1|ensembl:ENSMUSG00000037526(gene)|ensembl:ENSMUST00000042988(transcript)|ensembl:ENSMUST00000226299(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|mint:Q8CDJ3|reactome:R-MMU-1632852|dip:DIP-60849N	refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|ensembl:ENSG00000090989(gene)|ensembl:ENST00000346134(transcript)|ensembl:ENST00000381295(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051607"(defense response to virus)|go:"GO:0090543"(Flemming body)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|interpro:IPR019160|interpro:IPR028258|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016863898.1|dip:DIP-37579N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:Ha+zYY4aNPLZH0LQPz9s1SSK9R410090	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	intact-crc:AF7750CC98E990DE|rigid:eaNNUb/UbJczp1oIhyH1ifH4BJ8	false	flag tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96A65	uniprotkb:Q99J83	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-2911848|ensembl:ENSMUSP00000044769	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:atg5_mouse(display_long)|uniprotkb:Atg5(gene name)|psi-mi:Atg5(display_short)|uniprotkb:Apg5l(gene name synonym)|uniprotkb:APG5-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3509913|imex:IM-15774-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	ensembl:ENSMUSG00000038160(gene)|ensembl:ENSMUST00000039286(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0009620"(response to fungus)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|mint:Q99J83|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|refseq:XP_011241410.1|refseq:NP_444299.1|refseq:NP_001300942.1|dip:DIP-46420N	psi-mi:"MI:0469"(intact)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:XNYb541lnGe1mjdDHei6DNhiNfk10090	intact-crc:2E0D75AB3D931129|rigid:JPEugGyQtujuJTa2qmXrfnSj6aY	false	myc tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96A65	uniprotkb:Q14457	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3509920|imex:IM-15774-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:40AB15B3DEABFF4B|rigid:e0D/Bpe95Fn7tJgMO+vVNvrSQMY	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96A65	uniprotkb:Q8IYI6	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3509957|imex:IM-15774-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	intact-crc:D011358C8EBE1479|rigid:dVJuzP8AXjN8+WgDhiALGxKmpPc	false	-	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96A65	uniprotkb:O94817	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-746742|uniprotkb:Q6PJV2|ensembl:ENSP00000425107	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:atg12_human(display_long)|uniprotkb:Autophagy-related protein 12(gene name synonym)|uniprotkb:ATG12(gene name)|psi-mi:ATG12(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:APG12L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506758|imex:IM-15774-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|refseq:NP_004698.3|ensembl:ENSG00000145782(gene)|ensembl:ENST00000509910(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|refseq:NP_001264712.1|dip:DIP-46466N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1H|caution:ATG5/ATG12 antibody has been raised against the conjugated heterodimer rather than the individual proteins.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:V+K93xoWUNtOTJk4k03IP+Q+HfA9606	intact-crc:A4A608C3D14C541F|rigid:MQGvh3aVuYzRRR4Fco6g6vjy/T8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96A65	uniprotkb:Q9UPT5	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-720048|uniprotkb:Q96FF0|uniprotkb:Q9H8C3|uniprotkb:Q9H9X3|uniprotkb:Q9HA32|uniprotkb:Q8ND93|uniprotkb:Q8WV91|uniprotkb:B5MC69|uniprotkb:B8XXP2|ensembl:ENSP00000334100	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:exoc7_human(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506758|imex:IM-15774-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	refseq:NP_001013861.1|refseq:NP_001138769.1|refseq:NP_001138770.1|refseq:NP_001138771.1|refseq:NP_056034.2|ensembl:ENSG00000182473(gene)|ensembl:ENST00000335146(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032584"(growth cone membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|mint:Q9UPT5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_001269242.1|dip:DIP-37604N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1H|caution:ATG5/ATG12 antibody has been raised against the conjugated heterodimer rather than the individual proteins.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:f/uwscxIcAuG96QZzNMQtrzTmeU9606	intact-crc:A4A608C3D14C541F|rigid:MQGvh3aVuYzRRR4Fco6g6vjy/T8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96A65	uniprotkb:Q96KP1	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-465715|uniprotkb:Q5JPC8|uniprotkb:Q96AN6|uniprotkb:Q9NUZ8|uniprotkb:Q9UJM7|ensembl:ENSP00000230449|uniprotkb:B2RBE6	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:exoc2_human(display_long)|uniprotkb:EXOC2(gene name)|psi-mi:EXOC2(display_short)|uniprotkb:SEC5(gene name synonym)|uniprotkb:SEC5L1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506758|imex:IM-15774-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	ensembl:ENSG00000112685(gene)|ensembl:ENST00000230449(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR029175|interpro:IPR039481|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016866507.1|refseq:XP_016866508.1|refseq:XP_016866509.1|refseq:XP_016866510.1|refseq:XP_016866511.1|refseq:XP_016866512.1|refseq:XP_016866513.1|refseq:NP_060773.3|dip:DIP-31795N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1H|caution:ATG5/ATG12 antibody has been raised against the conjugated heterodimer rather than the individual proteins.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:7p+4vZ18z6u2PJY0GzbHY+ro0v89606	intact-crc:A4A608C3D14C541F|rigid:MQGvh3aVuYzRRR4Fco6g6vjy/T8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96A65	uniprotkb:Q9H1Y0	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506758|imex:IM-15774-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 1H|caution:ATG5/ATG12 antibody has been raised against the conjugated heterodimer rather than the individual proteins.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606	intact-crc:A4A608C3D14C541F|rigid:MQGvh3aVuYzRRR4Fco6g6vjy/T8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11234	uniprotkb:O94817	intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224	intact:EBI-746742|uniprotkb:Q6PJV2|ensembl:ENSP00000425107	psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)	psi-mi:atg12_human(display_long)|uniprotkb:Autophagy-related protein 12(gene name synonym)|uniprotkb:ATG12(gene name)|psi-mi:ATG12(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:APG12L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506815|imex:IM-15774-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)	reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|refseq:NP_004698.3|ensembl:ENSG00000145782(gene)|ensembl:ENST00000509910(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|refseq:NP_001264712.1|dip:DIP-46466N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3G|caution:ATG5/ATG12 antibody has been raised against the conjugated heterodimer rather than the individual proteins.|agonist:Sendai virus infection|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606	rogid:V+K93xoWUNtOTJk4k03IP+Q+HfA9606	intact-crc:373900F71D85D26D|rigid:9jRHXUn5gu5fWCxepdln1CKevrE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11234	uniprotkb:Q9H1Y0	intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224	intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072	psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)	psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506815|imex:IM-15774-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)	refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3G|caution:ATG5/ATG12 antibody has been raised against the conjugated heterodimer rather than the individual proteins.|agonist:Sendai virus infection|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606	rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606	intact-crc:373900F71D85D26D|rigid:9jRHXUn5gu5fWCxepdln1CKevrE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14457	uniprotkb:Q8IYI6	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3507290|imex:IM-15774-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4G|agonist:Nutrient deprivation|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	intact-crc:7321DDE22EF8D5C0|rigid:pVHOEUT3qhH/P9AloLD2XNLqP+E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O54921	uniprotkb:Q14457	intact:EBI-1036795	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:exoc2_rat(display_long)|uniprotkb:Exoc2(gene name)|psi-mi:Exoc2(display_short)|uniprotkb:Sec5(gene name synonym)|uniprotkb:Sec5l1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3507312|imex:IM-15774-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:1UAD|rgd:619961|refseq:NP_599241.2|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029175|reactome:R-RNO-264876|go:"GO:0000145"(exocyst)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR039481|reactome:R-RNO-5620916	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figs. 4J|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:SHbyRkZSRQjpKQefY/EYM9S5yJM10116	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:777551DF9947903B|rigid:5UvKw5HvsXqDz8s4yKKuEkLAk9A	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:Q8IYI6	uniprotkb:Q14457	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3507304|imex:IM-15774-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4I|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:0A00623D18A0ADD9|rigid:pVHOEUT3qhH/P9AloLD2XNLqP+E	false	myc tag:121-121	flag tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:Q8IYI6	uniprotkb:Q14457	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3509942|imex:IM-15774-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:EDEC79A829983F9D|rigid:RNab1KPRCMJnbMg7yDU8NLOLs0Q	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IYI6	uniprotkb:Q96A65	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3509942|imex:IM-15774-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	intact-crc:EDEC79A829983F9D|rigid:RNab1KPRCMJnbMg7yDU8NLOLs0Q	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IYI6	uniprotkb:Q4R379	intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33	intact:EBI-3509938	psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short)	psi-mi:ralb_macfa(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)|uniprotkb:QtsA-18830(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9541(macfa)|taxid:9541("Macaca fascicularis (Crab-eating macaque)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3509942|imex:IM-15774-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916	refseq:XP_005572983.1|refseq:XP_005572982.2|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR020849|refseq:NP_001306496.1|refseq:XP_015287459.1|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030496"(midbody)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|interpro:IPR027417|interpro:IPR028412	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606	rogid:LIDzjGBmVm6Lq9mS8XWNmeJMhoU9541	intact-crc:EDEC79A829983F9D|rigid:RNab1KPRCMJnbMg7yDU8NLOLs0Q	false	myc tag:?-?	flag tag:?-?|mutation:23-23	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11234	uniprotkb:Q99J83	intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224	intact:EBI-2911848|ensembl:ENSMUSP00000044769	psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)	psi-mi:atg5_mouse(display_long)|uniprotkb:Atg5(gene name)|psi-mi:Atg5(display_short)|uniprotkb:Apg5l(gene name synonym)|uniprotkb:APG5-like(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506798|imex:IM-15774-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)	ensembl:ENSMUSG00000038160(gene)|ensembl:ENSMUST00000039286(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0009620"(response to fungus)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|mint:Q99J83|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|refseq:XP_011241410.1|refseq:NP_444299.1|refseq:NP_001300942.1|dip:DIP-46420N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606	rogid:XNYb541lnGe1mjdDHei6DNhiNfk10090	intact-crc:595347D6221CCF2D|rigid:JXFBgJ4YeBLaf0FCnEtRxu9RcQ4	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P11234	uniprotkb:Q0VGK0	intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224	intact:EBI-3506805|ensembl:ENSRNOP00000075223	psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)	psi-mi:gbrl1_rat(display_long)|uniprotkb:Gabarapl1(gene name)|psi-mi:Gabarapl1(display_short)|uniprotkb:Gec1(gene name synonym)|uniprotkb:"GABA(A) receptor-associated protein-like 1"(gene name synonym)|uniprotkb:Glandular epithelial cell protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506807|imex:IM-15774-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)	rgd:1596143|refseq:NP_001037759.1|ensembl:ENSRNOG00000053362(gene)|ensembl:ENSRNOT00000077356(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016236"(macroautophagy)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0044297"(cell body)|go:"GO:0050811"(GABA receptor binding)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|reactome:R-RNO-1632852	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606	rogid:X3TVNoI2dr936S1k875QCIVQWbo10116	intact-crc:5A2EEBD1372590AD|rigid:7KxW6jiKsxk+gWND3C4jqLqZVqk	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q14457	uniprotkb:P11234	intact:EBI-949378|intact:EBI-28978189|ensembl:ENSP00000355231|ensembl:ENSP00000465364|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7	intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Bodemann et al. (2011)	pubmed:21241894|imex:IM-15774	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3506779|imex:IM-15774-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126581(gene)|ensembl:ENST00000361523(transcript)|ensembl:ENST00000590099(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|refseq:NP_003757.1|ensembl:ENSP00000355231|ensembl:ENSP00000465364|dip:DIP-44611N|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1	refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/01	2014/10/16	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606	intact-crc:05A3EE7B747204DC|rigid:ZaaiEV6tAHw6hS4jLICD/GMLj+8	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)