#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61508 uniprotkb:P16297 intact:EBI-3870665|uniprotkb:Q3U5Q5|ensembl:ENSMUSP00000112665 intact:EBI-3870668|uniprotkb:Q3TZT2|ensembl:ENSMUSP00000086820|ensembl:ENSMUSP00000127006 psi-mi:ecm1_mouse(display_long)|uniprotkb:Ecm1(gene name)|psi-mi:Ecm1(display_short)|uniprotkb:Secretory component p85(gene name synonym) psi-mi:il2rb_mouse(display_long)|uniprotkb:Il2rb(gene name)|psi-mi:Il2rb(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2011) pubmed:21217760|imex:IM-15785 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-3870671|imex:IM-15785-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031925.2|ensembl:ENSMUSG00000028108(gene)|ensembl:ENSMUST00000117507(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002020"(protease binding)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002828"(regulation of type 2 immune response)|go:"GO:0003416"(endochondral bone growth)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0043236"(laminin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR008605(Extracellular matrix 1)|interpro:IPR020858|reactome:R-MMU-114608|go:"GO:0030500"(regulation of bone mineralization) refseq:NP_032394.1|refseq:XP_006520540.1|refseq:XP_006520541.1|refseq:XP_006520542.1|refseq:XP_006520543.1|refseq:XP_006520544.1|ensembl:ENSMUSG00000068227(gene)|ensembl:ENSMUST00000089398(transcript)|ensembl:ENSMUST00000163494(transcript)|go:"GO:0004911"(interleukin-2 receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|rcsb pdb:6DG5|reactome:R-MMU-5673001|reactome:R-MMU-8983432|reactome:R-MMU-9020558|reactome:R-MMU-912526 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 8D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/04/13 2014/10/16 rogid:ddbYMXo/91FnvtB1uzroQ//1PD810090 rogid:H85gxyCuBxRPWb0/pglO88Gi4v010090 intact-crc:A0672B3745B1FAF3|rigid:AGuM3aVRJIlCB20PcN695Cabq5k false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)