#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O88778	uniprotkb:Q9Z214	intact:EBI-2271660	intact:EBI-2338940|uniprotkb:O08567|uniprotkb:O88800|uniprotkb:Q9QUJ8|uniprotkb:Q9QWN5	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:home1_rat(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Grabrucker et al. (2011)	mint:MINT-8142217|pubmed:21217644|imex:IM-15399|doi:10.1038/emboj.2010.336	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558913|mint:MINT-8142681|imex:IM-15399-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8142684(identity)	rgd:628725|refseq:NP_113895.1|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:XP_006231837.1|mint:Q9Z214|interpro:IPR044100|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|rcsb pdb:1DDV|rcsb pdb:1DDW|rcsb pdb:1I2H|rcsb pdb:3CVE|reactome:R-RNO-6794361|mint:MINT-8142698(identity)	go:"GO:0045202"(synapse)	-	-	figure legend:f1a f1b|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2011/03/02	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:7yzSvJnto6+5zXH000SPZOIYe3w10116	intact-crc:F26738B8F87B07BD|rigid:LeSaMApGxE2Antc3U0KIMsWX5OU	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O88778	uniprotkb:Q9QX74	intact:EBI-2271660	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Grabrucker et al. (2011)	mint:MINT-8142217|pubmed:21217644|imex:IM-15399|doi:10.1038/emboj.2010.336	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558913|mint:MINT-8142681|imex:IM-15399-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8142684(identity)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-8142683(identity)	go:"GO:0045202"(synapse)	-	-	figure legend:f1a f1b|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2011/03/02	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:F26738B8F87B07BD|rigid:LeSaMApGxE2Antc3U0KIMsWX5OU	false	-	binding-associated region:1411-1474(MINT-8142758)|green fluorescent protein tag:?-?(MINT-8142755)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O88778	uniprotkb:Q9Z214	intact:EBI-2271660	intact:EBI-2338940|uniprotkb:O08567|uniprotkb:O88800|uniprotkb:Q9QUJ8|uniprotkb:Q9QWN5	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:home1_rat(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Grabrucker et al. (2011)	mint:MINT-8142217|pubmed:21217644|imex:IM-15399|doi:10.1038/emboj.2010.336	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559037|mint:MINT-8151013|imex:IM-15399-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8151016(identity)	rgd:628725|refseq:NP_113895.1|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:XP_006231837.1|mint:Q9Z214|interpro:IPR044100|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|rcsb pdb:1DDV|rcsb pdb:1DDW|rcsb pdb:1I2H|rcsb pdb:3CVE|reactome:R-RNO-6794361|mint:MINT-8151025(identity)	go:"GO:0045202"(synapse)	-	-	figure legend:f4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2011/03/02	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:7yzSvJnto6+5zXH000SPZOIYe3w10116	intact-crc:5AAB3554E4C7231D|rigid:ENmoN5opVHFlktTKE2cg+A7XlSA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O88778	uniprotkb:Q9Z214	intact:EBI-2271660	intact:EBI-2338940|uniprotkb:O08567|uniprotkb:O88800|uniprotkb:Q9QUJ8|uniprotkb:Q9QWN5	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:home1_rat(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Grabrucker et al. (2011)	mint:MINT-8142217|pubmed:21217644|imex:IM-15399|doi:10.1038/emboj.2010.336	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558988|mint:MINT-8142690|imex:IM-15399-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8142693(identity)	rgd:628725|refseq:NP_113895.1|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:XP_006231837.1|mint:Q9Z214|interpro:IPR044100|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|rcsb pdb:1DDV|rcsb pdb:1DDW|rcsb pdb:1I2H|rcsb pdb:3CVE|reactome:R-RNO-6794361|mint:MINT-8142697(identity)	go:"GO:0045202"(synapse)	-	-	figure legend:f1a f1b|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2011/03/02	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:7yzSvJnto6+5zXH000SPZOIYe3w10116	intact-crc:A212189F34FAE65D|rigid:CHsrFp4+albpcrxqiLigTUgTNG4	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O88778	uniprotkb:Q9JLU4	intact:EBI-2271660	intact:EBI-6271152|uniprotkb:Q9WUY7|uniprotkb:Q9WV47	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:shan3_rat(display_long)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Prosap2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Grabrucker et al. (2011)	mint:MINT-8142217|pubmed:21217644|imex:IM-15399|doi:10.1038/emboj.2010.336	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558988|mint:MINT-8142690|imex:IM-15399-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8142693(identity)	go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|rcsb pdb:2F3N|rcsb pdb:2F44|rcsb pdb:5G4X|rcsb pdb:5O99|rcsb pdb:5OVA|rcsb pdb:5OVC|rcsb pdb:5OVP|rcsb pdb:5OVV|rcsb pdb:6EXJ|reactome:R-RNO-6794361|reactome:R-RNO-8853659|mint:Q9JLU4|rgd:69264|refseq:NP_067708.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:MINT-8142692(identity)	go:"GO:0045202"(synapse)	-	-	figure legend:f1a f1b|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2011/03/02	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:5f5+bUHHbxnta5KzhCtIoW/+MWk10116	intact-crc:A212189F34FAE65D|rigid:CHsrFp4+albpcrxqiLigTUgTNG4	false	-	binding-associated region:1599-1662(MINT-8142747)|green fluorescent protein tag:?-?(MINT-8142744)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)