#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01031	uniprotkb:D3JIB2	intact:EBI-8558308|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112|ensembl:ENSP00000223642	intact:EBI-8558292|intact:MINT-8143387	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	psi-mi:d3jib2_staau(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558286|mint:MINT-8143400|imex:IM-15401-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304092.1|refseq:NP_001726.2|ensembl:ENSG00000106804(gene)|ensembl:ENST00000223642(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019835"(cytolysis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR037562|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:7AD6|rcsb pdb:7AD7|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|mint:MINT-8143402(identity)	interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|rcsb pdb:3PRX|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|go:"GO:0005576"(extracellular region)|mint:MINT-8143404(identity)	-	function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:"Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)"|function:"Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections"|function:"Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis"	comment:mint	comment:mint|figure legend:f2 t1 st2 sf7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/03	2014/10/16	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	intact-crc:BAB987376353DC6C|rigid:a21Vs4qDsz7Wldqyn6CoineFoxg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01031	uniprotkb:Q91132	intact:EBI-8558308|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112|ensembl:ENSP00000223642	intact:EBI-7081824|uniprotkb:Q6RHR7|uniprotkb:Q6PQH3|intact:MINT-7906427	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	psi-mi:vco3_najka(display_long)|uniprotkb:Complement C3 homolog(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:8649(monocled cobra)|taxid:8649(Naja kaouthia)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558286|mint:MINT-8143400|imex:IM-15401-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304092.1|refseq:NP_001726.2|ensembl:ENSG00000106804(gene)|ensembl:ENST00000223642(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019835"(cytolysis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR037562|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:7AD6|rcsb pdb:7AD7|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|mint:MINT-8143402(identity)	mint:Q91132|interpro:IPR035711|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|rcsb pdb:3FRP|rcsb pdb:3HRZ|rcsb pdb:3HS0|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:6I2X|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR018933|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR019742|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR018081|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:MINT-8143403(identity)	-	function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:"Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)"|function:"Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections"|function:"Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis"	comment:mint	comment:mint|figure legend:f2 t1 st2 sf7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/03	2014/10/16	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	rogid:DX5XdQMIkCpMsZgFLCWuuOju5v88649	intact-crc:BAB987376353DC6C|rigid:a21Vs4qDsz7Wldqyn6CoineFoxg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01031	uniprotkb:Q91132	intact:EBI-8558308|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112|ensembl:ENSP00000223642	intact:EBI-7081824|uniprotkb:Q6RHR7|uniprotkb:Q6PQH3|intact:MINT-7906427	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	psi-mi:vco3_najka(display_long)|uniprotkb:Complement C3 homolog(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:8649(monocled cobra)|taxid:8649(Naja kaouthia)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558390|mint:MINT-8143413|imex:IM-15401-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304092.1|refseq:NP_001726.2|ensembl:ENSG00000106804(gene)|ensembl:ENST00000223642(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019835"(cytolysis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR037562|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:7AD6|rcsb pdb:7AD7|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|mint:MINT-8143415(identity)	mint:Q91132|interpro:IPR035711|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|rcsb pdb:3FRP|rcsb pdb:3HRZ|rcsb pdb:3HS0|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:6I2X|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR018933|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR019742|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR018081|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:MINT-8143417(identity)	-	function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:"Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)"|function:"Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections"|function:"Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis"	comment:mint	comment:mint|figure legend:f1 t1 st1 f3 f4 sf3 st3 sf5d sf9a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/03	2014/10/16	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	rogid:DX5XdQMIkCpMsZgFLCWuuOju5v88649	intact-crc:4041286832DB0A96|rigid:UI0e5do8zFW8Vu0jgkPnDQoaEi0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D3JIB2	uniprotkb:P01031	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-8558308|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112|ensembl:ENSP00000223642	psi-mi:d3jib2_staau(display_long)	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558427|mint:MINT-8143443|imex:IM-15401-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|rcsb pdb:3PRX|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|go:"GO:0005576"(extracellular region)|mint:MINT-8143450(identity)	refseq:NP_001304092.1|refseq:NP_001726.2|ensembl:ENSG00000106804(gene)|ensembl:ENST00000223642(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019835"(cytolysis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR037562|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:7AD6|rcsb pdb:7AD7|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|mint:MINT-8143446(identity)	-	comment:mint	function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:"Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)"|function:"Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections"|function:"Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis"	comment:homomint|comment:mint|figure legend:sf6c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.96x10^-5(molar)	2011/03/03	2014/10/16	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	intact-crc:77F1B7376D05F2E7|rigid:FCX5N/N3N4UZWhMJO2ofTOfwqok	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D3JIB2	uniprotkb:P01024	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907	psi-mi:d3jib2_staau(display_long)	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558427|mint:MINT-8143443|imex:IM-15401-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|rcsb pdb:3PRX|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|go:"GO:0005576"(extracellular region)|mint:MINT-8143450(identity)	refseq:NP_000055.2|dip:DIP-35180N|ensembl:ENSG00000125730(gene)|ensembl:ENST00000245907(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|mint:MINT-8143448(identity)	-	comment:mint	-	comment:homomint|comment:mint|figure legend:sf6c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.96x10^-5(molar)	2011/03/03	2014/10/16	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	intact-crc:77F1B7376D05F2E7|rigid:FCX5N/N3N4UZWhMJO2ofTOfwqok	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D3JIB2	uniprotkb:Q91132	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-7081824|uniprotkb:Q6RHR7|uniprotkb:Q6PQH3|intact:MINT-7906427	psi-mi:d3jib2_staau(display_long)	psi-mi:vco3_najka(display_long)|uniprotkb:Complement C3 homolog(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:8649(monocled cobra)|taxid:8649(Naja kaouthia)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558411|mint:MINT-8143431|imex:IM-15401-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|rcsb pdb:3PRX|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|go:"GO:0005576"(extracellular region)|mint:MINT-8143437(identity)	mint:Q91132|interpro:IPR035711|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|rcsb pdb:3FRP|rcsb pdb:3HRZ|rcsb pdb:3HS0|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:6I2X|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR018933|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR019742|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR018081|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:MINT-8143435(identity)	-	comment:mint	comment:mint	comment:mint|figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.4x10^-5(molar)	2011/03/03	2014/10/16	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:DX5XdQMIkCpMsZgFLCWuuOju5v88649	intact-crc:87D6BEA1748A2127|rigid:a21Vs4qDsz7Wldqyn6CoineFoxg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D3JIB2	uniprotkb:P01031	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-8558308|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112|ensembl:ENSP00000223642	psi-mi:d3jib2_staau(display_long)	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8558411|mint:MINT-8143431|imex:IM-15401-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|rcsb pdb:3PRX|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|go:"GO:0005576"(extracellular region)|mint:MINT-8143437(identity)	refseq:NP_001304092.1|refseq:NP_001726.2|ensembl:ENSG00000106804(gene)|ensembl:ENST00000223642(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005579"(membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019835"(cytolysis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR037562|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:7AD6|rcsb pdb:7AD7|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|mint:MINT-8143433(identity)	-	comment:mint	function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:"Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)"|function:"Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections"|function:"Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis"	comment:mint|figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.4x10^-5(molar)	2011/03/03	2014/10/16	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	intact-crc:87D6BEA1748A2127|rigid:a21Vs4qDsz7Wldqyn6CoineFoxg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)