#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O94603 uniprotkb:Q10990 intact:EBI-3505187|ensemblfungi:"SPCC622.16c.1:pep" intact:EBI-3505190|ensemblfungi:"SPAC17H9.19c.1:pep" psi-mi:jhd1_schpo(display_long)|uniprotkb:jhd1(gene name)|psi-mi:jhd1(display_short)|uniprotkb:epe1(gene name synonym)|uniprotkb:Heterochromatin-destabilizing protein epe1(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1(gene name synonym)|uniprotkb:SPCC622.16c(orf name) psi-mi:cdt2_schpo(display_long)|uniprotkb:cdt2(gene name)|psi-mi:cdt2(display_short)|uniprotkb:SPAC17H9.19c(orf name) psi-mi:"MI:0018"(two hybrid) Braun et al. (2011) imex:IM-15306|pubmed:21215368 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3505189|imex:IM-15306-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-2299718|reactome:R-SPO-3214842|refseq:NP_588188.1|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|ensemblfungi:SPCC622.16c(gene)|ensemblfungi:SPCC622.16c.1(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031454"|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0090052"(regulation of pericentric heterochromatin assembly)|go:"GO:0090054"(regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1905291"(positive regulation of CAMKK-AMPK signaling cascade)|go:"GO:1990342"(heterochromatin island)|interpro:IPR041070|reactome:R-SPO-8951664|reactome:R-SPO-983168 refseq:NP_593588.1|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|reactome:R-SPO-110314|ensemblfungi:SPAC17H9.19c(gene)|ensemblfungi:SPAC17H9.19c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:2000779"(regulation of double-strand break repair)|reactome:R-SPO-8951664|interpro:IPR036322 psi-mi:"MI:0469"(intact) - - figure legend:Fig 3A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/25 2014/10/16 rogid:JA4WCUdDyMbJ83aYNRSWp5T/dw4284812 rogid:W10gqdlH5nukRT0Zp7/9rrCcekU284812 intact-crc:254C55E5D4EE1620|rigid:jevNc1YdlIfgMLg90lNuZhgM+m8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40381 uniprotkb:O94603 intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" intact:EBI-3505187|ensemblfungi:"SPCC622.16c.1:pep" psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:jhd1_schpo(display_long)|uniprotkb:jhd1(gene name)|psi-mi:jhd1(display_short)|uniprotkb:epe1(gene name synonym)|uniprotkb:Heterochromatin-destabilizing protein epe1(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1(gene name synonym)|uniprotkb:SPCC622.16c(orf name) psi-mi:"MI:0018"(two hybrid) Braun et al. (2011) imex:IM-15306|pubmed:21215368 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3505196|imex:IM-15306-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO reactome:R-SPO-2299718|reactome:R-SPO-3214842|refseq:NP_588188.1|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|ensemblfungi:SPCC622.16c(gene)|ensemblfungi:SPCC622.16c.1(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031454"|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0090052"(regulation of pericentric heterochromatin assembly)|go:"GO:0090054"(regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1905291"(positive regulation of CAMKK-AMPK signaling cascade)|go:"GO:1990342"(heterochromatin island)|interpro:IPR041070|reactome:R-SPO-8951664|reactome:R-SPO-983168 psi-mi:"MI:0469"(intact) crc64:F505CC8AC5E75EAB - figure legend:Fig. 3A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/25 2014/10/16 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 rogid:JA4WCUdDyMbJ83aYNRSWp5T/dw4284812 intact-crc:EE9CC8B121D63357|rigid:7tcXIqrsKl3bimo5v2lpzpSC7KE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q10990 uniprotkb:O94603 intact:EBI-3505190|ensemblfungi:"SPAC17H9.19c.1:pep" intact:EBI-3505187|ensemblfungi:"SPCC622.16c.1:pep" psi-mi:cdt2_schpo(display_long)|uniprotkb:cdt2(gene name)|psi-mi:cdt2(display_short)|uniprotkb:SPAC17H9.19c(orf name) psi-mi:jhd1_schpo(display_long)|uniprotkb:jhd1(gene name)|psi-mi:jhd1(display_short)|uniprotkb:epe1(gene name synonym)|uniprotkb:Heterochromatin-destabilizing protein epe1(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1(gene name synonym)|uniprotkb:SPCC622.16c(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Braun et al. (2011) imex:IM-15306|pubmed:21215368 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3505207|imex:IM-15306-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593588.1|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|reactome:R-SPO-110314|ensemblfungi:SPAC17H9.19c(gene)|ensemblfungi:SPAC17H9.19c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:2000779"(regulation of double-strand break repair)|reactome:R-SPO-8951664|interpro:IPR036322 reactome:R-SPO-2299718|reactome:R-SPO-3214842|refseq:NP_588188.1|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|ensemblfungi:SPCC622.16c(gene)|ensemblfungi:SPCC622.16c.1(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031454"|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0090052"(regulation of pericentric heterochromatin assembly)|go:"GO:0090054"(regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1905291"(positive regulation of CAMKK-AMPK signaling cascade)|go:"GO:1990342"(heterochromatin island)|interpro:IPR041070|reactome:R-SPO-8951664|reactome:R-SPO-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2011/01/25 2014/10/16 rogid:W10gqdlH5nukRT0Zp7/9rrCcekU284812 rogid:JA4WCUdDyMbJ83aYNRSWp5T/dw4284812 intact-crc:97F9324FAB9FBC23|rigid:jevNc1YdlIfgMLg90lNuZhgM+m8 false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)