#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O95999	uniprotkb:Q9BXL7	intact:EBI-958922|ensembl:ENSP00000498104|uniprotkb:Q5VUF1	intact:EBI-7006141|intact:EBI-28969961|ensembl:ENSP00000380150|uniprotkb:Q2NKN7|intact:MINT-193901|uniprotkb:A4D1Z7|uniprotkb:Q548H3	psi-mi:bcl10_human(display_long)|uniprotkb:BCL10(gene name)|psi-mi:BCL10(display_short)|uniprotkb:CIPER(gene name synonym)|uniprotkb:CLAP(gene name synonym)|uniprotkb:Cellular homolog of vCARMEN(gene name synonym)|uniprotkb:Mammalian CARD-containing adapter molecule E10(gene name synonym)|uniprotkb:Cellular-E10(gene name synonym)|uniprotkb:CARD-like apoptotic protein(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 10(gene name synonym)|uniprotkb:CED-3/ICH-1 prodomain homologous E10-like regulator(gene name synonym)|uniprotkb:CARD-containing molecule enhancing NF-kappa-B(gene name synonym)	psi-mi:car11_human(display_long)|uniprotkb:CARD11(gene name)|psi-mi:CARD11(display_short)|uniprotkb:CARMA1(gene name synonym)|uniprotkb:CARD-containing MAGUK protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eitelhuber et al. (2011)	mint:MINT-8143006|doi:10.1038/emboj.2010.331|pubmed:21157432|imex:IM-15394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8545291|mint:MINT-8143041|imex:IM-15394-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142867(gene)|ensembl:ENST00000648566(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0002020"(protease binding)|go:"GO:0002096"(polkadots)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032094"(response to food)|go:"GO:0032449"(CBM complex)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032761"(positive regulation of lymphotoxin A production)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR033238|interpro:IPR042143|mint:O95999|rcsb pdb:2MB9|rcsb pdb:6BZE|rcsb pdb:6GK2|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866654|refseq:NP_003912.1|dip:DIP-29740N|mint:MINT-8143045(identity)	ensembl:ENSP00000380150|refseq:NP_001311210.1|refseq:XP_011513888.1|ensembl:ENSG00000198286(gene)|ensembl:ENST00000396946(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032449"(CBM complex)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR033538|interpro:IPR036034|interpro:IPR042141|mint:Q9BXL7|rcsb pdb:4JUP|rcsb pdb:4LWD|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|refseq:NP_115791.3|dip:DIP-41797N|mint:MINT-8143043(identity)	-	-	comment:mint|comment:homomint|function:Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10	figure legend:f3d f3e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2011/03/02	2014/10/16	rogid:BUrlS8JdWGi4LWWgp0FfpILCeDY9606	rogid:6Brt3NrkQt4m0X6OTPgixpH3E5w9606	intact-crc:5226A161331525F4|rigid:u9rSzOuXq8uD8SgV9oAu1Gz2/wU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95999	uniprotkb:Q9UDY8	intact:EBI-958922|ensembl:ENSP00000498104|uniprotkb:Q5VUF1	intact:EBI-1047372|uniprotkb:Q9NTB7|uniprotkb:Q9ULX4|ensembl:ENSP00000497997	psi-mi:bcl10_human(display_long)|uniprotkb:BCL10(gene name)|psi-mi:BCL10(display_short)|uniprotkb:CIPER(gene name synonym)|uniprotkb:CLAP(gene name synonym)|uniprotkb:Cellular homolog of vCARMEN(gene name synonym)|uniprotkb:Mammalian CARD-containing adapter molecule E10(gene name synonym)|uniprotkb:Cellular-E10(gene name synonym)|uniprotkb:CARD-like apoptotic protein(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 10(gene name synonym)|uniprotkb:CED-3/ICH-1 prodomain homologous E10-like regulator(gene name synonym)|uniprotkb:CARD-containing molecule enhancing NF-kappa-B(gene name synonym)	psi-mi:malt1_human(display_long)|uniprotkb:MALT lymphoma-associated translocation(gene name synonym)|uniprotkb:Paracaspase(gene name synonym)|uniprotkb:MALT1(gene name)|psi-mi:MALT1(display_short)|uniprotkb:MLT(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eitelhuber et al. (2011)	mint:MINT-8143006|doi:10.1038/emboj.2010.331|pubmed:21157432|imex:IM-15394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8545291|mint:MINT-8143041|imex:IM-15394-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142867(gene)|ensembl:ENST00000648566(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0002020"(protease binding)|go:"GO:0002096"(polkadots)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032094"(response to food)|go:"GO:0032449"(CBM complex)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032761"(positive regulation of lymphotoxin A production)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR033238|interpro:IPR042143|mint:O95999|rcsb pdb:2MB9|rcsb pdb:6BZE|rcsb pdb:6GK2|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866654|refseq:NP_003912.1|dip:DIP-29740N|mint:MINT-8143045(identity)	refseq:NP_006776.1|refseq:NP_776216.1|rcsb pdb:3BFO|rcsb pdb:3K0W|rcsb pdb:3UO8|rcsb pdb:3UOA|rcsb pdb:3V4O|rcsb pdb:3V55|rcsb pdb:4I1P|rcsb pdb:4I1R|rcsb pdb:6F7I|rcsb pdb:6GK2|rcsb pdb:6H4A|rcsb pdb:6YN8|rcsb pdb:6YN9|rcsb pdb:7A41|rcsb pdb:7AK0|rcsb pdb:7AK1|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-5660668|interpro:IPR033540|interpro:IPR036179|interpro:IPR037940|interpro:IPR041077|mint:Q9UDY8|rcsb pdb:2G7R|ensembl:ENSG00000172175(gene)|ensembl:ENST00000649217(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001923"(B-1 B cell differentiation)|go:"GO:0002020"(protease binding)|go:"GO:0002096"(polkadots)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006952"(defense response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008233"(peptidase activity)|go:"GO:0009620"(response to fungus)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032449"(CBM complex)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051168"(nuclear export)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029030|dip:DIP-42833N|mint:MINT-8143048(identity)	-	-	-	figure legend:f3d f3e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2011/03/02	2014/10/16	rogid:BUrlS8JdWGi4LWWgp0FfpILCeDY9606	rogid:WsMuEt3d/LX9MrX957HmGCkIKP89606	intact-crc:5226A161331525F4|rigid:u9rSzOuXq8uD8SgV9oAu1Gz2/wU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BXL7	uniprotkb:O95999	intact:EBI-7006141|intact:EBI-28969961|ensembl:ENSP00000380150|uniprotkb:Q2NKN7|intact:MINT-193901|uniprotkb:A4D1Z7|uniprotkb:Q548H3	intact:EBI-958922|ensembl:ENSP00000498104|uniprotkb:Q5VUF1	psi-mi:car11_human(display_long)|uniprotkb:CARD11(gene name)|psi-mi:CARD11(display_short)|uniprotkb:CARMA1(gene name synonym)|uniprotkb:CARD-containing MAGUK protein 1(gene name synonym)	psi-mi:bcl10_human(display_long)|uniprotkb:BCL10(gene name)|psi-mi:BCL10(display_short)|uniprotkb:CIPER(gene name synonym)|uniprotkb:CLAP(gene name synonym)|uniprotkb:Cellular homolog of vCARMEN(gene name synonym)|uniprotkb:Mammalian CARD-containing adapter molecule E10(gene name synonym)|uniprotkb:Cellular-E10(gene name synonym)|uniprotkb:CARD-like apoptotic protein(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 10(gene name synonym)|uniprotkb:CED-3/ICH-1 prodomain homologous E10-like regulator(gene name synonym)|uniprotkb:CARD-containing molecule enhancing NF-kappa-B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eitelhuber et al. (2011)	mint:MINT-8143006|doi:10.1038/emboj.2010.331|pubmed:21157432|imex:IM-15394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8545344|mint:MINT-8143014|imex:IM-15394-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000380150|refseq:NP_001311210.1|refseq:XP_011513888.1|ensembl:ENSG00000198286(gene)|ensembl:ENST00000396946(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032449"(CBM complex)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR033538|interpro:IPR036034|interpro:IPR042141|mint:Q9BXL7|rcsb pdb:4JUP|rcsb pdb:4LWD|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|refseq:NP_115791.3|dip:DIP-41797N|mint:MINT-8143016(identity)	ensembl:ENSG00000142867(gene)|ensembl:ENST00000648566(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0002020"(protease binding)|go:"GO:0002096"(polkadots)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032094"(response to food)|go:"GO:0032449"(CBM complex)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032761"(positive regulation of lymphotoxin A production)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR033238|interpro:IPR042143|mint:O95999|rcsb pdb:2MB9|rcsb pdb:6BZE|rcsb pdb:6GK2|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866654|refseq:NP_003912.1|dip:DIP-29740N|mint:MINT-8143017(identity)	-	comment:mint|comment:homomint|function:Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10	-	figure legend:f3c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:6Brt3NrkQt4m0X6OTPgixpH3E5w9606	rogid:BUrlS8JdWGi4LWWgp0FfpILCeDY9606	intact-crc:AFC22CE63100DFBE|rigid:a7d1fVXryd17Oghx91e5We/MJZw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Z0H7	uniprotkb:Q8CIS0	intact:EBI-8545413|intact:UNK-5560748|uniprotkb:Q3UBN4|ensembl:ENSMUSP00000029842	intact:EBI-643994|uniprotkb:Q4VA14|uniprotkb:Q6KAS3|uniprotkb:Q8BYV0	psi-mi:bcl10_mouse(display_long)|uniprotkb:Bcl10(gene name)|psi-mi:Bcl10(display_short)|uniprotkb:Ciper(gene name synonym)|uniprotkb:Clap(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 10(gene name synonym)|uniprotkb:CED-3/ICH-1 prodomain homologous E10-like regulator(gene name synonym)|uniprotkb:CARD-containing molecule enhancing NF-kappa-B(gene name synonym)|uniprotkb:Cellular homolog of vCARMEN(gene name synonym)|uniprotkb:Mammalian CARD-containing adapter molecule E10(gene name synonym)|uniprotkb:Cellular-E10(gene name synonym)|uniprotkb:CARD-like apoptotic protein(gene name synonym)	psi-mi:car11_mouse(display_long)|uniprotkb:Card11(gene name)|psi-mi:Card11(display_short)|uniprotkb:CARD-containing MAGUK protein 1(gene name synonym)|uniprotkb:Carma1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eitelhuber et al. (2011)	mint:MINT-8143006|doi:10.1038/emboj.2010.331|pubmed:21157432|imex:IM-15394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8545407|mint:MINT-8143055|imex:IM-15394-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033870.1|dip:DIP-60309N|ensembl:ENSMUSG00000028191(gene)|ensembl:ENSMUST00000029842(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0002020"(protease binding)|go:"GO:0002096"(polkadots)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009620"(response to fungus)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019209"(kinase activator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032094"(response to food)|go:"GO:0032449"(CBM complex)|go:"GO:0002250"(adaptive immune response)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR033238|interpro:IPR042143|reactome:R-MMU-1169091|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-5607764|reactome:R-MMU-8866654|mint:MINT-8143059(identity)	refseq:NP_780571.2|reactome:R-MMU-2871837|go:"GO:0001772"(immunological synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032449"(CBM complex)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046649"(lymphocyte activation)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR033538|interpro:IPR036034|interpro:IPR042141|rcsb pdb:4I16|go:"GO:0045121"(membrane raft)|reactome:R-MMU-1169091|reactome:R-MMU-202424|dip:DIP-49692N|reactome:R-MMU-5607764|mint:MINT-8143057(identity)	-	comment:mint|comment:homomint|function:Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex	-	figure legend:f3f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2011/03/02	2014/10/16	rogid:20gxkBjtsGLmnabow2Dv/z8Vew410090	rogid:bMy3/cFVvB9lmJfmhD77Ag35Cdo10090	intact-crc:EBD303967481FCB6|rigid:yuvSLIcrYiQ+O3RzcRUROJmuoEo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)