#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11413 uniprotkb:P04792 intact:EBI-4289891|uniprotkb:Q8IU88|uniprotkb:D3DWX9|uniprotkb:Q16000|uniprotkb:Q16765|uniprotkb:Q8IUA6|uniprotkb:Q8IU70|uniprotkb:Q96PQ2|ensembl:ENSP00000377192|ensembl:ENSP00000377194 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:g6pd_human(display_long)|uniprotkb:G6PD(gene name)|psi-mi:G6PD(display_short) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cosentino et al. (2011) mint:MINT-8142225|pubmed:21157431|imex:IM-15340|doi:10.1038/emboj.2010.330 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8544675|mint:MINT-8142240|imex:IM-15340-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000393.4|refseq:NP_001035810.1|ensembl:ENSG00000160211(gene)|ensembl:ENST00000393562(transcript)|ensembl:ENST00000393564(transcript)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010041"("response to iron(III) ion")|go:"GO:0010734"(negative regulation of protein glutathionylation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032094"(response to food)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|rcsb pdb:1QKI|rcsb pdb:2BH9|rcsb pdb:2BHL|rcsb pdb:5UKW|rcsb pdb:6E07|rcsb pdb:6E08|rcsb pdb:6JYU|rcsb pdb:6VA0|rcsb pdb:6VA7|rcsb pdb:6VA8|rcsb pdb:6VA9|rcsb pdb:6VAQ|reactome:R-HSA-5628897|reactome:R-HSA-71336|mint:MINT-8142243(identity) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|mint:MINT-8142242(identity) - - crc64:1B4DC44A6F6606D5 figure legend:f2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ag02603)|taxid:9606(Homo sapiens) - 2011/03/01 2014/10/16 rogid:qW8uk6xBGtrxlsosIH6gEG1ZfWA9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 intact-crc:41F043F356DFF1F2|rigid:W62HQ2aW17gBoVQBxEgbld4/mKw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04792 uniprotkb:P11413 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 intact:EBI-4289891|uniprotkb:Q8IU88|uniprotkb:D3DWX9|uniprotkb:Q16000|uniprotkb:Q16765|uniprotkb:Q8IUA6|uniprotkb:Q8IU70|uniprotkb:Q96PQ2|ensembl:ENSP00000377192|ensembl:ENSP00000377194 psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:g6pd_human(display_long)|uniprotkb:G6PD(gene name)|psi-mi:G6PD(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cosentino et al. (2011) mint:MINT-8142225|pubmed:21157431|imex:IM-15340|doi:10.1038/emboj.2010.330 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8544687|mint:MINT-8142253|imex:IM-15340-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|mint:MINT-8142255(identity) refseq:NP_000393.4|refseq:NP_001035810.1|ensembl:ENSG00000160211(gene)|ensembl:ENST00000393562(transcript)|ensembl:ENST00000393564(transcript)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010041"("response to iron(III) ion")|go:"GO:0010734"(negative regulation of protein glutathionylation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032094"(response to food)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|rcsb pdb:1QKI|rcsb pdb:2BH9|rcsb pdb:2BHL|rcsb pdb:5UKW|rcsb pdb:6E07|rcsb pdb:6E08|rcsb pdb:6JYU|rcsb pdb:6VA0|rcsb pdb:6VA7|rcsb pdb:6VA8|rcsb pdb:6VA9|rcsb pdb:6VAQ|reactome:R-HSA-5628897|reactome:R-HSA-71336|mint:MINT-8142257(identity) - crc64:1B4DC44A6F6606D5 - figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ag02603)|taxid:9606(Homo sapiens) - 2011/03/01 2014/10/16 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rogid:qW8uk6xBGtrxlsosIH6gEG1ZfWA9606 intact-crc:ECDA059F9A038FD0|rigid:W62HQ2aW17gBoVQBxEgbld4/mKw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)