#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9JKD8	uniprotkb:Q03347	intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484	intact:EBI-3863873|uniprotkb:O08598|uniprotkb:Q62049|uniprotkb:Q9ESB9|uniprotkb:Q9ET65	psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym)	psi-mi:runx1_mouse(display_long)|uniprotkb:Runx1(gene name)|psi-mi:Runx1(display_short)|uniprotkb:Aml1(gene name synonym)|uniprotkb:Cbfa2(gene name synonym)|uniprotkb:Pebp2ab(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lazarevic et al. (2011)	imex:IM-15734|pubmed:21151104	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863884|imex:IM-15734-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048666"(neuron development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0071336"(regulation of hair follicle cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000872"(positive regulation of progesterone secretion)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|rcsb pdb:1EAN|rcsb pdb:1EAO|rcsb pdb:1EAQ|rcsb pdb:1HJB|rcsb pdb:1HJC|rcsb pdb:1IO4|rcsb pdb:2J6W|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|dip:DIP-40723N|reactome:R-MMU-549127|reactome:R-MMU-8877330|reactome:R-MMU-8931987|reactome:R-MMU-8934593|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-8939243|reactome:R-MMU-8939245|reactome:R-MMU-8939246|reactome:R-MMU-8939247|reactome:R-MMU-9018519	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5A, 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/25	2014/10/16	rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090	rogid:1rh6vkqvcnroruSaiTl+xBjDpms10090	intact-crc:45928192B1DA6EF2|rigid:1mM2oHzljxZqsv974qFVz+fyKno	false	mutation disrupting interaction:304-304	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q64131	uniprotkb:Q9JKD8	intact:EBI-3863889|uniprotkb:B2FDG4|uniprotkb:Q99P92|uniprotkb:Q9R199|ensembl:ENSMUSP00000113159	intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484	psi-mi:runx3_mouse(display_long)|uniprotkb:Runx3(gene name)|psi-mi:Runx3(display_short)|uniprotkb:Aml2(gene name synonym)|uniprotkb:Cbfa3(gene name synonym)|uniprotkb:Pebp2a3(gene name synonym)|uniprotkb:Acute myeloid leukemia 2 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-3(gene name synonym)|uniprotkb:Oncogene AML-2(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha C subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha C subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha C subunit(gene name synonym)	psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lazarevic et al. (2011)	imex:IM-15734|pubmed:21151104	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863876|imex:IM-15734-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000070691(gene)|ensembl:ENSMUST00000119564(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031175"(neuron projection development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048469"(cell maturation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|reactome:R-MMU-8941855|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951430|reactome:R-MMU-8951671|reactome:R-MMU-8951936|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-60276N	refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/03/25	2014/10/16	rogid:ZZlEFZIQxxYtN+avXVRV0yXlOPI10090	rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090	intact-crc:D06B514311B75C68|rigid:ZyyP3AoqUUP3S0TmdL17u42l/cQ	false	myc tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q03347	uniprotkb:Q9JKD8	intact:EBI-3863873|uniprotkb:O08598|uniprotkb:Q62049|uniprotkb:Q9ESB9|uniprotkb:Q9ET65	intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484	psi-mi:runx1_mouse(display_long)|uniprotkb:Runx1(gene name)|psi-mi:Runx1(display_short)|uniprotkb:Aml1(gene name synonym)|uniprotkb:Cbfa2(gene name synonym)|uniprotkb:Pebp2ab(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lazarevic et al. (2011)	imex:IM-15734|pubmed:21151104	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863913|imex:IM-15734-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048666"(neuron development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0071336"(regulation of hair follicle cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000872"(positive regulation of progesterone secretion)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|rcsb pdb:1EAN|rcsb pdb:1EAO|rcsb pdb:1EAQ|rcsb pdb:1HJB|rcsb pdb:1HJC|rcsb pdb:1IO4|rcsb pdb:2J6W|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|dip:DIP-40723N|reactome:R-MMU-549127|reactome:R-MMU-8877330|reactome:R-MMU-8931987|reactome:R-MMU-8934593|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-8939243|reactome:R-MMU-8939245|reactome:R-MMU-8939246|reactome:R-MMU-8939247|reactome:R-MMU-9018519	refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2011/03/25	2014/10/16	rogid:1rh6vkqvcnroruSaiTl+xBjDpms10090	rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090	intact-crc:A798E8C9029120ED|rigid:1mM2oHzljxZqsv974qFVz+fyKno	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03347	uniprotkb:Q9JKD8	intact:EBI-3863873|uniprotkb:O08598|uniprotkb:Q62049|uniprotkb:Q9ESB9|uniprotkb:Q9ET65	intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484	psi-mi:runx1_mouse(display_long)|uniprotkb:Runx1(gene name)|psi-mi:Runx1(display_short)|uniprotkb:Aml1(gene name synonym)|uniprotkb:Cbfa2(gene name synonym)|uniprotkb:Pebp2ab(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lazarevic et al. (2011)	imex:IM-15734|pubmed:21151104	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863906|imex:IM-15734-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048666"(neuron development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0071336"(regulation of hair follicle cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000872"(positive regulation of progesterone secretion)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|rcsb pdb:1EAN|rcsb pdb:1EAO|rcsb pdb:1EAQ|rcsb pdb:1HJB|rcsb pdb:1HJC|rcsb pdb:1IO4|rcsb pdb:2J6W|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|dip:DIP-40723N|reactome:R-MMU-549127|reactome:R-MMU-8877330|reactome:R-MMU-8931987|reactome:R-MMU-8934593|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-8939243|reactome:R-MMU-8939245|reactome:R-MMU-8939246|reactome:R-MMU-8939247|reactome:R-MMU-9018519	refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2011/03/25	2014/10/16	rogid:1rh6vkqvcnroruSaiTl+xBjDpms10090	rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090	intact-crc:4EC3A255347FC8C9|rigid:1mM2oHzljxZqsv974qFVz+fyKno	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)