#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92900-2	uniprotkb:P38919	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q9BZI7	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-372780|uniprotkb:Q0VAK8|uniprotkb:Q9H1J0|uniprotkb:D3DWI3|uniprotkb:D3DWI4|ensembl:ENSP00000276201	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:ren3b_human(display_long)|uniprotkb:RENT3B(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 3B(gene name synonym)|uniprotkb:Up-frameshift suppressor 3 homolog B(gene name synonym)|uniprotkb:UPF3X(gene name synonym)|uniprotkb:UPF3B(gene name)|psi-mi:UPF3B(display_short)|uniprotkb:Up-frameshift suppressor 3 homolog on chromosome X(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	refseq:NP_075386.1|refseq:NP_542199.1|ensembl:ENSG00000125351(gene)|ensembl:ENST00000276201(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051028"(mRNA transport)|interpro:IPR005120(Nonsense-mediated decay UPF3)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034979|interpro:IPR035979|interpro:IPR039722|rcsb pdb:1UW4|rcsb pdb:2XB2|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|dip:DIP-31143N	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:Gb7+eHYaODU5NxYLJC38bT2dOpw9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q9HAU5	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-372073|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373|ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:rent2_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENSG00000151461(gene)|ensembl:ENST00000356352(transcript)|ensembl:ENST00000357604(transcript)|ensembl:ENST00000397053(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q8IZH2	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-372406|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39|ensembl:ENSP00000264951	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|ensembl:ENSG00000114127(gene)|ensembl:ENST00000264951(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033574"(response to testosterone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1905795"(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|dip:DIP-31174N	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:P11940	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q86US8	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-3232100|ensembl:ENSP00000263073|uniprotkb:O94837|uniprotkb:Q9UF60|uniprotkb:Q86VH6|uniprotkb:B7Z874	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:est1a_human(display_long)|uniprotkb:SMG6(gene name)|psi-mi:SMG6(display_short)|uniprotkb:C17orf31(gene name synonym)|uniprotkb:EST1A(gene name synonym)|uniprotkb:KIAA0732(gene name synonym)|uniprotkb:EST1-like protein A(gene name synonym)|uniprotkb:Ever shorter telomeres 1A(gene name synonym)|uniprotkb:Smg-6 homolog(gene name synonym)|uniprotkb:Telomerase subunit EST1A(gene name synonym)|uniprotkb:hSmg5/7a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	ensembl:ENST00000263073(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|interpro:IPR029060|mint:Q86US8|rcsb pdb:2DOK|rcsb pdb:2HWW|rcsb pdb:2HWX|rcsb pdb:4UM2|reactome:R-HSA-975957|ensembl:ENSG00000070366(gene)|refseq:XP_011522071.1|refseq:XP_011522077.1|refseq:NP_060045.4|refseq:NP_001243756.1|refseq:NP_001243757.1|refseq:NP_001269255.1|refseq:XP_005256626.1|refseq:XP_005256628.1|refseq:XP_016879888.1	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:UoAA9ikMFv3EHZZozUAOkWWPrRM9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q92540	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q9UPR3	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3400857|imex:IM-15275-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606	intact-crc:5219AF553FF16228|rigid:HLNxDAJgBF5wg23sbpFxZlLLXUU	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92900-2	uniprotkb:Q86US8	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	intact:EBI-3232100|ensembl:ENSP00000263073|uniprotkb:O94837|uniprotkb:Q9UF60|uniprotkb:Q86VH6|uniprotkb:B7Z874	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:est1a_human(display_long)|uniprotkb:SMG6(gene name)|psi-mi:SMG6(display_short)|uniprotkb:C17orf31(gene name synonym)|uniprotkb:EST1A(gene name synonym)|uniprotkb:KIAA0732(gene name synonym)|uniprotkb:EST1-like protein A(gene name synonym)|uniprotkb:Ever shorter telomeres 1A(gene name synonym)|uniprotkb:Smg-6 homolog(gene name synonym)|uniprotkb:Telomerase subunit EST1A(gene name synonym)|uniprotkb:hSmg5/7a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3401013|imex:IM-15275-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	ensembl:ENST00000263073(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|interpro:IPR029060|mint:Q86US8|rcsb pdb:2DOK|rcsb pdb:2HWW|rcsb pdb:2HWX|rcsb pdb:4UM2|reactome:R-HSA-975957|ensembl:ENSG00000070366(gene)|refseq:XP_011522071.1|refseq:XP_011522077.1|refseq:NP_060045.4|refseq:NP_001243756.1|refseq:NP_001243757.1|refseq:NP_001269255.1|refseq:XP_005256626.1|refseq:XP_005256628.1|refseq:XP_016879888.1	psi-mi:"MI:0469"(intact)	isoform-comment:No experimental confirmation available	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	rogid:UoAA9ikMFv3EHZZozUAOkWWPrRM9606	intact-crc:B5D1D2F6615CE9F0|rigid:LgIo8lqNB2BSsJUgev2v+B/Vn0s	false	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPR3	uniprotkb:Q92900-2	intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7	intact:EBI-373492|intact:EBI-7196940|intact:MINT-4931121|ensembl:ENSP00000262803	psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym)	psi-mi:q92900-2(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Franks et al. (2010)	pubmed:21145460|imex:IM-15275	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3401025|imex:IM-15275-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2	intact:EBI-373471(rent1_human)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000262803(transcript)|uniprotkb:Q92900-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available	figure legend:Supp. Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/01/06	2014/10/16	rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606	rogid:AEVnI6GRsFLhLLd1uqqsCGrDm0I9606	intact-crc:1397279968592C54|rigid:khxu4gvW91AKa4C21iblW65BfNU	false	-	myc tag:?-?|mutation increasing interaction:636-637|mutation increasing interaction:498-498	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)