#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12814	uniprotkb:O15265	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866219|imex:IM-17207-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|entrezgene/locuslink:87(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:A4EF42F29F85B6DE|rigid:BJWmvqLNuaBKh3xo401INGauzxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:P35609	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866233|imex:IM-17207-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N|entrezgene/locuslink:88(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:23A92FE05552D87E|rigid:uQc2arl9maP7lz4YgaKQZxddRWU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00468	uniprotkb:O15265	intact:EBI-947482|uniprotkb:Q5SVA2|uniprotkb:Q60FE1|uniprotkb:Q7KYS8|uniprotkb:Q8N4J5|uniprotkb:Q96IC1|uniprotkb:Q9BTD4|uniprotkb:Q5SVA1	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:agrin_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866263|imex:IM-17207-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940978.2|interpro:IPR004850(Agrin NtA)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:XP_005244806.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003884(Factor I membrane attack complex)|mint:O00468|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050808"(synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-419037|reactome:R-HSA-4420332|reactome:R-HSA-975634|interpro:IPR036058|interpro:IPR036364|refseq:NP_001292204.1	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:LRk4v4aYLk5kep9EIbjjiCGM7OM9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:C871DE1539EC57B8|rigid:M1f2bTgN+ZOz9mwB2jNrvUZcOGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43707	uniprotkb:O15265	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866243|imex:IM-17207-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N|entrezgene/locuslink:81(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:FA558C53F4C5E2A2|rigid:qRnGK5+fBqb6HnXPt3rIYQqvKhU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q9BZ11	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-946778|uniprotkb:A0A1K6|uniprotkb:Q5JT75|uniprotkb:Q5JT76|uniprotkb:Q8N0W6|ensembl:ENSP00000348912	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:ada33_human(display_long)|uniprotkb:ADAM33(gene name)|psi-mi:ADAM33(display_short)|uniprotkb:UNQ873/PRO1891(orf name)|uniprotkb:C20orf153(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866253|imex:IM-17207-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_079496.1|refseq:NP_694882.1|refseq:NP_001269376.1|ensembl:ENSG00000149451(gene)|ensembl:ENST00000356518(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1R54|rcsb pdb:1R55|entrezgene/locuslink:80332(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:gzVnsL4kcvBtwlxaNuxbY1gArx89606	intact-crc:0F8BF184420AE354|rigid:JrpKdBKhwj3/aUqE9Oz7PXhtRBU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:O95967	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866355|imex:IM-17207-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	intact-crc:072F2A705334D260|rigid:o/inPqkcrEBQA6I21BYvhuSSjBg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q9P209	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866307|imex:IM-17207-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	intact-crc:300B680E21B269BE|rigid:FUC6dg7Isc+szkyiWS7YpQgWCkE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2V7	uniprotkb:O15265	intact:EBI-3866319|uniprotkb:Q86V49|uniprotkb:Q5T0U1|uniprotkb:Q9ULT5|uniprotkb:Q6AI19|ensembl:ENSP00000397441	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:cog6_human(display_long)|uniprotkb:COG6(gene name)|psi-mi:COG6(display_short)|uniprotkb:KIAA1134(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 6(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866317|imex:IM-17207-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138551.1|refseq:NP_065802.1|dip:DIP-48931N|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0070085"(glycosylation)|interpro:IPR010490(Conserved oligomeric complex COG6)|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|ensembl:ENSG00000133103(gene)|ensembl:ENST00000455146(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|entrezgene/locuslink:57511(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:1S6ym3UxcjqPpQ9WCWf3060I9jE9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:1B04C80B13243642|rigid:3uXpbDDlgZV+s89E699ctg8ZMTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12805	uniprotkb:O15265	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|ensembl:ENSP00000347596|ensembl:ENSP00000378058|uniprotkb:B4DW75	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866345|imex:IM-17207-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115380(gene)|ensembl:ENST00000355426(transcript)|ensembl:ENST00000394555(transcript)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0008083"(growth factor activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR032973|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|entrezgene/locuslink:2202(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:9F636CC34656F8BC|rigid:e+RZioq/G1X0ymNKe2QJP2/Eas4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q9NZV1	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-2835534|uniprotkb:Q7LCQ5|uniprotkb:Q59GH0|uniprotkb:Q9H318|uniprotkb:Q2M2G4|ensembl:ENSP00000280527	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:crim1_human(display_long)|uniprotkb:CRIM1(gene name)|psi-mi:CRIM1(display_short)|uniprotkb:S52(gene name synonym)|uniprotkb:Cysteine-rich repeat-containing protein S52(gene name synonym)|uniprotkb:UNQ1886/PRO4330(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866335|imex:IM-17207-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_057525.1|ensembl:ENSG00000150938(gene)|ensembl:ENST00000280527(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR004094(Proteinase inhibitor I15, antistasin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011061(Proteinase inhibitor I14/I15, hirudin/antistatin)|mint:Q9NZV1|go:"GO:0016021"(integral component of membrane)|dip:DIP-58932N|entrezgene/locuslink:51232(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:7oEUkDAWyQgIlQecOcBSn+nnHX49606	intact-crc:63A4E1830216611F|rigid:edfFSmiM8BMgTpyt6mjSGcWpVqM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q9BWT7	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-3866279|uniprotkb:Q9UGR5|uniprotkb:Q5TFG6|uniprotkb:Q9Y3H0|uniprotkb:Q9UGR6|uniprotkb:Q14CQ8|uniprotkb:Q8NC81|ensembl:ENSP00000251973|ensembl:ENSP00000384570	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:car10_human(display_long)|uniprotkb:CARD10(gene name)|psi-mi:CARD10(display_short)|uniprotkb:CARMA3(gene name synonym)|uniprotkb:CARD-containing MAGUK protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866277|imex:IM-17207-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_055365.2|ensembl:ENSG00000100065(gene)|ensembl:ENST00000251973(transcript)|ensembl:ENST00000403299(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032449"(CBM complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|entrezgene/locuslink:29775(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:yJp/p3R99TARtQeCdhx/MTd6pSs9606	intact-crc:AC0586744324C412|rigid:4RdvNVOilK1m3SqSM01mJMVAiJA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:O15265	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866297|imex:IM-17207-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:83E2FBE302A723D5|rigid:0INZqg0yXdE3KbfbHSPMPTtkMKU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:O60229	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-949233|ensembl:ENSP00000353109|intact:EBI-1104807|uniprotkb:Q8TBQ5|uniprotkb:Q9NSZ4|uniprotkb:Q9Y2A5|uniprotkb:Q6ZN45|uniprotkb:A8MSI4|uniprotkb:J3QSW6|intact:EBI-3866438|uniprotkb:C9JQ37	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:kalrn_human(display_long)|uniprotkb:KALRN(gene name)|psi-mi:KALRN(display_short)|uniprotkb:DUET(gene name synonym)|uniprotkb:DUO(gene name synonym)|uniprotkb:HAPIP(gene name synonym)|uniprotkb:TRAD(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866443|imex:IM-17207-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036865|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-5687128|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|ensembl:ENSG00000160145(gene)|ensembl:ENST00000360013(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|refseq:NP_001309929.1|refseq:NP_001019831.2|refseq:NP_003938.1|refseq:NP_008995.2|refseq:NP_001309930.1|refseq:NP_001309917.1|refseq:NP_001309918.1|refseq:NP_001309923.1|refseq:NP_001309924.1|refseq:NP_001309925.1|refseq:NP_001309926.1|refseq:NP_001309927.1|refseq:NP_001309928.1|entrezgene/locuslink:8997(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2019/08/05	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:E7oPA6ps2iq0KD8jlTCm/mNQj949606	intact-crc:042E4FD1C332276A|rigid:qFa2e0Nj8j+TK9zArq1Lz8KqJHk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y219	uniprotkb:O15265	intact:EBI-946223|uniprotkb:Q9UE17|uniprotkb:Q9UE99|uniprotkb:Q9UNK8|uniprotkb:Q9Y6P9|uniprotkb:Q9Y6Q0|ensembl:ENSP00000328169	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:jag2_human(display_long)|uniprotkb:JAG2(gene name)|psi-mi:JAG2(display_short)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866428|imex:IM-17207-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002217.3|refseq:NP_660142.1|ensembl:ENSG00000184916(gene)|ensembl:ENST00000331782(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003016"(respiratory system process)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008083"(growth factor activity)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042492"(gamma-delta T cell differentiation)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:1990134"(epithelial cell apoptotic process involved in palatal shelf morphogenesis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|mint:Q9Y219|rcsb pdb:5MW5|rcsb pdb:5MW7|rcsb pdb:5MWF|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|go:"GO:0005887"(integral component of plasma membrane)|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507|entrezgene/locuslink:3714(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:GoH5Lw1zl+3dhA4RSpJTyQ0LY4Q9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:CD0BD80B11B21EA1|rigid:hmzp5ciQgHbSdXrZOVn+7vfY95M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:P28799	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866418|imex:IM-17207-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N|entrezgene/locuslink:2896(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	intact-crc:BAE91F57A5E117F4|rigid:SdCVtiJdpLXFvSn7jfuv8VW+lco	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JY77	uniprotkb:O15265	intact:EBI-2514717|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934|uniprotkb:Q96LA1|uniprotkb:O43168	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:gasp1_human(display_long)|uniprotkb:GPRASP1(gene name)|psi-mi:GPRASP1(display_short)|uniprotkb:GASP(gene name synonym)|uniprotkb:KIAA0443(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866408|imex:IM-17207-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198932(gene)|ensembl:ENST00000361600(transcript)|ensembl:ENST00000415986(transcript)|ensembl:ENST00000444152(transcript)|ensembl:ENST00000537097(transcript)|ensembl:ENST00000652542(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:1990172"(G protein-coupled receptor catabolic process)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:XP_016885470.1|refseq:XP_016885471.1|refseq:NP_001092880.1|refseq:NP_001092881.1|refseq:NP_001171656.1|refseq:NP_055525.3|ensembl:ENSP00000355146|ensembl:ENSP00000393691|ensembl:ENSP00000409420|ensembl:ENSP00000445683|ensembl:ENSP00000498934|entrezgene/locuslink:9737(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:hV+EvmQTl209eBHMYEB0Pq21jYo9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:37145051C47998A3|rigid:+nH/dMiMBtUiznLjjbzfVG8Qp/w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q08378	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-355782|uniprotkb:O43241|uniprotkb:Q6P9C7|uniprotkb:Q86XW3|uniprotkb:Q8TDA9|uniprotkb:Q8WZA3|uniprotkb:A5PKX6|intact:EBI-28985028|ensembl:ENSP00000204726|ensembl:ENSP00000410378	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:goga3_human(display_long)|uniprotkb:GOLGA3(gene name)|psi-mi:GOLGA3(display_short)|uniprotkb:Golgin-160(gene name synonym)|uniprotkb:Golgi complex-associated protein of 170 kDa(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866398|imex:IM-17207-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001166028.1|refseq:NP_005886.2|ensembl:ENSP00000204726|ensembl:ENSP00000410378|ensembl:ENST00000456883|ensembl:ENSP00000409303|ensembl:ENST00000545875|ensembl:ENSP00000442603|ensembl:ENSG00000090615(gene)|ensembl:ENST00000204726(transcript)|ensembl:ENST00000450791(transcript)|go:"GO:0045296"(cadherin binding)|go:"GO:0090498"(extrinsic component of Golgi membrane)|interpro:IPR033288|mint:Q08378|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9696270|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|refseq:XP_006719799.1|refseq:XP_006719800.1|entrezgene/locuslink:2802(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:7AjSzX3sUzfKpZkvdKDM0L//zYM9606	intact-crc:AAD57897A4F430F3|rigid:DI8IrBdNZtisiCtNE6Dsc1bmlkk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P02751	uniprotkb:O15265	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866375|imex:IM-17207-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|entrezgene/locuslink:2335(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:27B695DC53529C02|rigid:R5L75rKXgGutnp05vqAnAioTeyo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:P35555	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866365|imex:IM-17207-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N|entrezgene/locuslink:2200(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2019/04/15	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	intact-crc:D4EB5E305737E1C3|rigid:2kKL41UTka08U7+T4zwwSq9HbTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:O15265	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866388|imex:IM-17207-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:1A657897A4832C82|rigid:nJkB8Xpj2KpbJSo1b76DxYYXanU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55268	uniprotkb:O15265	intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866463|imex:IM-17207-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N|entrezgene/locuslink:3913(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:E2848D205684F79A|rigid:y70ZDEnt7dfL6aJd/jyhndNQcso	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UWE0	uniprotkb:O15265	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417|ensembl:ENSP00000322937|ensembl:ENSP00000362419|ensembl:ENSP00000502167	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866473|imex:IM-17207-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|ensembl:ENSG00000148356(gene)|ensembl:ENST00000300417(transcript)|ensembl:ENST00000323301(transcript)|ensembl:ENST00000373322(transcript)|ensembl:ENST00000675448(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046755"(viral budding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|mint:Q6UWE0|reactome:R-HSA-983168|entrezgene/locuslink:90678(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:A7ED367C54F6979A|rigid:4MKvVFtx3Pw8P0vOFrg+rP5OoTU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N2S1	uniprotkb:O15265	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866486|imex:IM-17207-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379|entrezgene/locuslink:8425(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:CB00392D759EFC20|rigid:rwEloRkhKx6IIl/6wkkzK5P10i0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:O00339	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-949020|uniprotkb:A8K106|uniprotkb:E7EW74|uniprotkb:E9PD48|uniprotkb:E9PGL2|ensembl:ENSP00000254898|ensembl:ENSP00000430487|uniprotkb:Q6UWA5|uniprotkb:Q7Z5X1|uniprotkb:Q8NDE6|uniprotkb:Q96FT5|uniprotkb:Q9NSZ1	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:matn2_human(display_long)|uniprotkb:MATN2(gene name)|psi-mi:MATN2(display_short)|uniprotkb:UNQ193/PRO219(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866499|imex:IM-17207-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	dip:DIP-47267N|ensembl:ENSG00000132561(gene)|ensembl:ENST00000254898(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0031012"(extracellular matrix)|ensembl:ENST00000520016(transcript)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019466|interpro:IPR026823|interpro:IPR030747|interpro:IPR036337|interpro:IPR036465|refseq:NP_002371.3|refseq:NP_085072.2|refseq:NP_001304677.1|entrezgene/locuslink:4147(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:umvJixncdhOkQvywPNFjPo1Aqx89606	intact-crc:728A7803024F4158|rigid:o3DW48Lf/sYuodupRbjRAfaB2rY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:O75095	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-947597|uniprotkb:Q5VV39|uniprotkb:Q4AC86|ensembl:ENSP00000348982	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:megf6_human(display_long)|uniprotkb:MEGF6(gene name)|psi-mi:MEGF6(display_short)|uniprotkb:EGFL3(gene name synonym)|uniprotkb:KIAA0815(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866509|imex:IM-17207-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001400.3|ensembl:ENSG00000162591(gene)|ensembl:ENST00000356575(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|mint:O75095|entrezgene/locuslink:1953(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:/4HcLiv4UEW2qmvoV2OTj110y1I9606	intact-crc:E5FFBF4055F814FA|rigid:CvFnXCQjZ9+XQ4pcs6gUBOuquhs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z7M0	uniprotkb:O15265	intact:EBI-947617|uniprotkb:O75097|uniprotkb:A8KAY0|ensembl:ENSP00000251268	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:megf8_human(display_long)|uniprotkb:MEGF8(gene name)|psi-mi:MEGF8(display_short)|uniprotkb:EGFL4(gene name synonym)|uniprotkb:KIAA0817(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 4(gene name synonym)|uniprotkb:C19orf49(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866519|imex:IM-17207-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001401.2|refseq:NP_001258867.1|ensembl:ENSG00000105429(gene)|ensembl:ENST00000251268(transcript)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0055113"(epiboly involved in gastrulation with mouth forming second)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0097155"(fasciculation of sensory neuron axon)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016201(Plexin-like fold)|interpro:IPR018097|interpro:IPR024731|interpro:IPR035914|mint:Q7Z7M0|go:"GO:0048704"(embryonic skeletal system morphogenesis)|entrezgene/locuslink:1954(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:NaA9e3P2Wh8y5vrZQQPOYHh8ogc9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:F4AD9A7AC44532BC|rigid:n1WT+CJY1w7HM8P1rrBxUsgfp48	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6WCQ1	uniprotkb:O15265	intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866529|imex:IM-17207-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133030(gene)|ensembl:ENST00000341712(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q6WCQ1|reactome:R-HSA-6802952|refseq:NP_055949.2|refseq:NP_958431.2|entrezgene/locuslink:23164(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:E96E3C3183CDFDAE|rigid:4HMAZKsnMd1yHvqdTy3p50aqIic	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q8TAS6	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-2622017	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:q8tas6_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866453|imex:IM-17207-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	interpro:IPR002049(EGF-like, laminin)|interpro:IPR013015(Laminin IV)|refseq:NP_002282.2|interpro:IPR000742(EGF-like, type 3)|entrezgene/locuslink:3912(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:HCEb+we2ZRZClQiN5+RQx/CcT7g9606	intact-crc:D2F39EDCE3E29B73|rigid:dYe+D2h3DZoy0SVIxonsZSS0PPM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZL4	uniprotkb:O15265	intact:EBI-721802|uniprotkb:Q59FK8|uniprotkb:Q6ZPD1|uniprotkb:Q7L8F7|uniprotkb:Q9H5H5|uniprotkb:Q9NT00|uniprotkb:Q96HW1|uniprotkb:B4DME2|ensembl:ENSP00000263433	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:pp12c_human(display_long)|uniprotkb:LENG3(gene name synonym)|uniprotkb:MBS85(gene name synonym)|uniprotkb:Protein phosphatase 1 myosin-binding subunit of 85 kDa(gene name synonym)|uniprotkb:PPP1R12C(gene name)|psi-mi:PPP1R12C(display_short)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866596|imex:IM-17207-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060077.1|refseq:NP_001258547.1|refseq:XP_005259070.1|ensembl:ENSG00000125503(gene)|ensembl:ENST00000263433(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031205|interpro:IPR031775|interpro:IPR036770|mint:Q9BZL4|entrezgene/locuslink:54776(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:q24mbt02IydCWtQyNXmNVWav/i89606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:DDDB018443B92BB7|rigid:XB7ewJ2x8bwIsFzBTP7bwvmo4kw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q92832	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-947754|uniprotkb:Q4VB91|uniprotkb:Q4VB90|uniprotkb:B2CKC1|uniprotkb:Q9Y472|uniprotkb:Q6NSY8|ensembl:ENSP00000349654	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:nell1_human(display_long)|uniprotkb:NEL-like protein 1(gene name synonym)|uniprotkb:Nel-related protein 1(gene name synonym)|uniprotkb:NELL1(gene name)|psi-mi:NELL1(display_short)|uniprotkb:NRP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866546|imex:IM-17207-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_006148.2|refseq:NP_963845.1|refseq:NP_001275642.1|refseq:NP_001275643.1|ensembl:ENSG00000165973(gene)|ensembl:ENST00000357134(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR024731|mint:Q92832|rcsb pdb:6POL|entrezgene/locuslink:4745(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:nC7vtd2PeL7K7QjSVJDoDJE3owk9606	intact-crc:D22A6A07F735FD76|rigid:zXstZ2iYYJFC8b4B3Tz/E0+8Dbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q99435	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-946274|intact:EBI-2845314|uniprotkb:B7Z2U7|uniprotkb:B7Z5Q4|uniprotkb:B7Z9J5|uniprotkb:B7Z9U3|uniprotkb:Q96JS2|ensembl:ENSP00000390680|ensembl:ENSP00000394612	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:nell2_human(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866556|imex:IM-17207-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001138579.1|refseq:NP_001138580.1|refseq:NP_001138581.1|refseq:NP_001138582.1|refseq:NP_006150.1|refseq:XP_011536698.1|refseq:XP_005268962.1|dip:DIP-49927N|ensembl:ENSG00000184613(gene)|ensembl:ENST00000429094(transcript)|ensembl:ENST00000452445(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0008201"(heparin binding)|go:"GO:0070050"(neuron cellular homeostasis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|mint:Q99435|rcsb pdb:6POG|reactome:R-HSA-428542|entrezgene/locuslink:4753(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	intact-crc:4A769AA1828EE988|rigid:jUkOdCveuP3nsUvAHnKsQ4TK8T4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3T9	uniprotkb:O15265	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866566|imex:IM-17207-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756|entrezgene/locuslink:26155(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:6D25A8BB11AE72A7|rigid:OIShM1q1Ni5Y2dTLxO0fUSui/z8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:O15265	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866576|imex:IM-17207-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:F91C1CF135260AB5|rigid:cKjl5H9wUqlu45i9og6KbhknrL4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q8ND90	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-302345|uniprotkb:O95144|uniprotkb:Q8NG07|ensembl:ENSP00000318914|uniprotkb:A8K4L5	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:pnma1_human(display_long)|uniprotkb:PNMA1(gene name)|psi-mi:PNMA1(display_short)|uniprotkb:MA1(gene name synonym)|uniprotkb:Neuron- and testis-specific protein 1(gene name synonym)|uniprotkb:37 kDa neuronal protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866586|imex:IM-17207-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_006020.4|ensembl:ENSG00000176903(gene)|ensembl:ENST00000316836(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR026523|interpro:IPR026528|mint:Q8ND90|entrezgene/locuslink:9240(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:/lx3CB7d/dv4xIgWQrCETPA0Qcw9606	intact-crc:637B7CA302CE423F|rigid:nGb09xhVQoP5oBYYZFGR03aY2po	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15276	uniprotkb:O15265	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866606|imex:IM-17207-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|go:"GO:0008083"(growth factor activity)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|interpro:IPR029880|rcsb pdb:1P4U|rcsb pdb:1TU3|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|ensembl:ENSG00000029725(gene)|ensembl:ENST00000537505(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:9135(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:45B0782056CE9A2C|rigid:PZyY5Gk6VtzfN+32ibx1r+tT/+s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:O15265	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866616|imex:IM-17207-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:B2C03D90E76547ED|rigid:0s3zxaS5HI2rn+6e57dqKHnlOz8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q8IUQ4	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866641|imex:IM-17207-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N|entrezgene/locuslink:6477(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:2A92F710130C4B00|rigid:4DCFzlIryS0T/CKepKSOHENwYQ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	intact:EBI-3866651	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	-	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:a6nkh4_human(display_short)|psi-mi:EBI-3866651(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)|uniprotkb:hCG_33348(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866655|imex:IM-17207-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	uniprotkb:A6NKH4(uniprot-removed-ac)|entrezgene/locuslink:6642(identity)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:aZ7C4m0blH28NcSmQf0dh3IO5vs9606	intact-crc:075AFC16E7C87A8D|rigid:Px9e5A1foUUMSYiqenPGY5ns/bs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:O43609	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-3866665|uniprotkb:Q6PNE0|uniprotkb:D3DNX6|ensembl:ENSP00000343785|ensembl:ENSP00000377871|ensembl:ENSP00000480540|ensembl:ENSP00000481675|ensembl:ENSP00000498292	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:spy1_human(display_long)|uniprotkb:SPRY1(gene name)|psi-mi:SPRY1(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866671|imex:IM-17207-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_005832.1|refseq:NP_955359.1|refseq:NP_001244967.1|refseq:NP_001244968.1|refseq:XP_005262743.1|ensembl:ENSG00000164056(gene)|ensembl:ENST00000339241(transcript)|ensembl:ENST00000394339(transcript)|ensembl:ENST00000610581(transcript)|ensembl:ENST00000622283(transcript)|ensembl:ENST00000651917(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001759"(organ induction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR007875(Sprouty)|interpro:IPR030783|mint:O43609|reactome:R-HSA-182971|refseq:XP_016863124.1|entrezgene/locuslink:10252(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:tbucIEQYibDQbBC1xVIZVDH2nIY9606	intact-crc:0C758CE3F64F487F|rigid:8DrU2zZYShhRqibuaSLQAptt4HM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:P28290	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-722905|uniprotkb:Q8N7H2|uniprotkb:Q7Z7L2|uniprotkb:Q8N1L3|uniprotkb:Q8N263|uniprotkb:Q8NEN5|uniprotkb:Q96E36|uniprotkb:Q68DA6|uniprotkb:Q96PW1|uniprotkb:A8K6T0|intact:EBI-28986959|ensembl:ENSP00000388731	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:itpi2_human(display_long)|uniprotkb:ITPRID2(gene name)|psi-mi:ITPRID2(display_short)|uniprotkb:CS1(gene name synonym)|uniprotkb:Cleavage signal-1 protein(gene name synonym)|uniprotkb:ITPR-interacting domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1927(gene name synonym)|uniprotkb:KRAP(gene name synonym)|uniprotkb:Ki-ras-induced actin-interacting protein(gene name synonym)|uniprotkb:SSFA2(gene name synonym)|uniprotkb:Sperm-specific antigen 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866681|imex:IM-17207-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001123917.1|refseq:NP_006742.2|refseq:NP_001274432.1|refseq:NP_001274433.1|ensembl:ENST00000320370|ensembl:ENSP00000314669|ensembl:ENSP00000388731|dip:DIP-47271N|ensembl:ENSG00000138434(gene)|ensembl:ENST00000431877(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR026648|interpro:IPR029325|interpro:IPR029326|interpro:IPR043444|entrezgene/locuslink:6744(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:oLYBDg++fr2C4VnIkkP5xhll5dw9606	intact-crc:7FD91D27A62EE9A0|rigid:p70UTvfvdyoQVTlG6ikgAHpF9Vg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:B0YJA4	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-3866691	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:b0yja4_human(display_long)|uniprotkb:THY1(gene name)|psi-mi:THY1(display_short)|uniprotkb:Thy-1 membrane glycoprotein(gene name synonym)|uniprotkb:hCG_14965(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866695|imex:IM-17207-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	interpro:IPR036179|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013151(Immunoglobulin)|refseq:NP_006279.2|refseq:NP_001298089.1|refseq:NP_001298091.1|go:"GO:0001525"(angiogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR033292|entrezgene/locuslink:7070(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:oJQb/vrYoN49IHy3OI4SmCXYtJY9606	intact-crc:80AF203F887B0F02|rigid:+MvBikNARGs1dNwXddf5+tvPu5k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q12933	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866705|imex:IM-17207-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N|entrezgene/locuslink:7186(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	intact-crc:8CC2BC73476428CB|rigid:oHU0eHz3i9wqEPxFlhXt2zhQnas	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EP0	uniprotkb:O15265	intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|ensembl:ENSP00000315112|ensembl:ENSP00000496609|uniprotkb:A0A962	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866631|imex:IM-17207-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000092098(gene)|ensembl:ENSG00000285152(gene)|ensembl:ENST00000324103(transcript)|ensembl:ENST00000647495(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071797"(LUBAC complex)|go:"GO:0097039"(protein linear polyubiquitination)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|refseq:NP_060469.4|refseq:NP_001297261.1|ensembl:ENSP00000315112|ensembl:ENST00000559275|ensembl:ENSP00000453574|ensembl:ENST00000642631|ensembl:ENSP00000494011|ensembl:ENSP00000496609|dip:DIP-44034N|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5X0W|rcsb pdb:6GZY|rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|reactome:R-HSA-5357905|reactome:R-HSA-5357956|rcsb pdb:5LJN|entrezgene/locuslink:55072(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:5QylozByg2G8/5LnkorkdY5fPec9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:4489DF96FF8AC0F4|rigid:m2G+edMU4KAYAsc2XcJvL66vkD4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZP0	uniprotkb:O00555	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866787|imex:IM-17207-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|entrezgene/locuslink:10006(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:DEBC817E8FDDC4DD|rigid:hfCZYfAWtoSo6VybZys3CY4ZvEk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q9BZC7	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-311024|uniprotkb:A6NED5|uniprotkb:Q5W9G5|uniprotkb:Q76MW7|uniprotkb:Q5SPY5|intact:EBI-3866765|uniprotkb:Q9HC28|ensembl:ENSP00000360666	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:abca2_human(display_long)|uniprotkb:ABCA2(gene name)|psi-mi:ABCA2(display_short)|uniprotkb:ABC2(gene name synonym)|uniprotkb:KIAA1062(gene name synonym)|uniprotkb:ATP-binding cassette transporter 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866777|imex:IM-17207-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001597.2|refseq:NP_997698.1|ensembl:ENST00000341511|ensembl:ENSP00000344155|ensembl:ENSP00000360666|refseq:XP_006717059.1|ensembl:ENSG00000107331(gene)|ensembl:ENST00000371605(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001573"(ganglioside metabolic process)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006684"(sphingomyelin metabolic process)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010008"(endosome membrane)|go:"GO:0010872"(regulation of cholesterol esterification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0032383"(regulation of intracellular cholesterol transport)|go:"GO:0032384"(negative regulation of intracellular cholesterol transport)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060049"(regulation of protein glycosylation)|go:"GO:0061135"(endopeptidase regulator activity)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071072"(negative regulation of phospholipid biosynthetic process)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0099038"(ceramide floppase activity)|go:"GO:0099040"(ceramide translocation)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0150110"(negative regulation of cholesterol esterification)|go:"GO:1901873"(regulation of post-translational protein modification)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|go:"GO:1904375"(regulation of protein localization to cell periphery)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|go:"GO:1905601"(negative regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|interpro:IPR030366|mint:Q9BZC7|reactome:R-HSA-1369062|entrezgene/locuslink:20(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:0R9SMBvlpKcrbgL2J8Q5kaxy/O89606	intact-crc:0C23FDD3AB3D1664|rigid:vjTNZnjxtEh3LnB5iYgCesYKfBs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:P04275	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866755|imex:IM-17207-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|entrezgene/locuslink:7450(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:61253D20E6E70EBE|rigid:wpSyJR5woaxjhyUiL6Mi5mbpChI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHD9	uniprotkb:O15265	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866745|imex:IM-17207-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825|entrezgene/locuslink:29978(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:312E8BEC51A91AF5|rigid:0ERiZmcNApP4M8HGoR3ipQmGMSQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6PKC3	uniprotkb:O15265	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866735|imex:IM-17207-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056998.4|refseq:NP_001290376.1|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066(gene)|ensembl:ENST00000356957(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|entrezgene/locuslink:51061(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:673E9A3E246E8455|rigid:p0BWOGQKRefNKnWDP+0fM1GX+bI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	uniprotkb:Q9BYV2	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-2130429|uniprotkb:A5D8T7|uniprotkb:Q53SY4|uniprotkb:Q9BYV3|ensembl:ENSP00000369415	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:tri54_human(display_long)|uniprotkb:TRIM54(gene name)|psi-mi:TRIM54(display_short)|uniprotkb:MURF(gene name synonym)|uniprotkb:MURF3(gene name synonym)|uniprotkb:RNF30(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 3(gene name synonym)|uniprotkb:Muscle-specific RING finger protein(gene name synonym)|uniprotkb:RING finger protein 30(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866725|imex:IM-17207-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_115935.3|refseq:NP_912730.2|interpro:IPR027370|interpro:IPR033492|interpro:IPR042752|rcsb pdb:3Q1D|ensembl:ENSG00000138100(gene)|ensembl:ENST00000380075(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017903|interpro:IPR017907|entrezgene/locuslink:57159(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:rxNKa4ddkMuN1HQlCnhYo2Ypi589606	intact-crc:6E74E054428F4516|rigid:miVklFeKv8qePvBQMdylG/v7lrE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36406	uniprotkb:O15265	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866715|imex:IM-17207-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:9A392E8187AF6E4B|rigid:e7MQHy4qLaiQdCiv4O6FalPLK58	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:O43681	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866876|imex:IM-17207-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2|entrezgene/locuslink:439(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	intact-crc:FD69DE80FF0C8444|rigid:PZRo6N6b20+9VzQ/S9D+JD+hCww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z5H3	uniprotkb:O00555	intact:EBI-3866859|uniprotkb:A0AVP7|uniprotkb:A5YM75|uniprotkb:Q6ZSB0|uniprotkb:B9EGA0|uniprotkb:O00152|uniprotkb:B4DED8|uniprotkb:C9JDM2|ensembl:ENSP00000249601	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:rhg22_human(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866857|imex:IM-17207-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334667.1|refseq:XP_011538306.1|refseq:NP_067049.2|refseq:NP_001242953.1|refseq:NP_001242955.1|refseq:NP_001242954.1|ensembl:ENSP00000249601|ensembl:ENST00000417247|ensembl:ENSP00000410054|ensembl:ENST00000417912|ensembl:ENSP00000412461|ensembl:ENST00000435790|ensembl:ENSP00000416701|ensembl:ENSG00000128805(gene)|ensembl:ENST00000249601(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|mint:Q7Z5H3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|entrezgene/locuslink:58504(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:B6GppfBTWo7eKA5XTxP6oOG56789606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:41E63979CE252AFB|rigid:jaq4RMtlaly/2+V+C+3xwO/6jsA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q96CW1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-297683|ensembl:ENSP00000292807|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|uniprotkb:D3DNT1	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866847|imex:IM-17207-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENSG00000161203(gene)|ensembl:ENST00000292807(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0034622"|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0031623"(receptor internalization)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|reactome:R-HSA-182218|refseq:NP_001020376.1|refseq:NP_004059.2|refseq:NP_001298127.1|entrezgene/locuslink:1173(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606	intact-crc:0F3D8DF288EE85F2|rigid:xUm9e/WeTHVMHp+KGUrM5FGpbe0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q86SJ2	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3866830|uniprotkb:Q96CN8|uniprotkb:Q4VBP6|uniprotkb:Q7Z4A0|ensembl:ENSP00000266581|ensembl:ENSP00000406020|ensembl:ENSP00000449034	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:amgo2_human(display_long)|uniprotkb:AMIGO2(gene name)|psi-mi:AMIGO2(display_short)|uniprotkb:ALI1(gene name synonym)|uniprotkb:AMIGO-2(gene name synonym)|uniprotkb:Alivin-1(gene name synonym)|uniprotkb:Differentially expressed in gastric adenocarcinomas(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866837|imex:IM-17207-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001137140.1|refseq:NP_862830.1|refseq:XP_005268894.1|ensembl:ENST00000266581(transcript)|ensembl:ENST00000429635(transcript)|ensembl:ENST00000550413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007420"(brain development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051965"(positive regulation of synapse assembly)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031286|interpro:IPR032675|interpro:IPR036179|reactome:R-HSA-9013149|reactome:R-HSA-9013423|ensembl:ENSG00000139211(gene)|entrezgene/locuslink:347902(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:c5JBCzA3CGbyFLbRePuJSNfZO/I9606	intact-crc:EEA476F288C2C458|rigid:A3SSsZA9O2eGpUq0gDZLZZTfTp0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P04075	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866820|imex:IM-17207-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|entrezgene/locuslink:226(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	intact-crc:45BCEE23EC1F9906|rigid:BJHIYTi/rouazROKdstDKGwhrQo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q5XG79	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3866265	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:q5xg79_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866810|imex:IM-17207-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	interpro:IPR036058|interpro:IPR036364|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR003884(Factor I membrane attack complex)|entrezgene/locuslink:375790(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:Nf7Tp8klSvZzD/weLTIV7rRDIi89606	intact-crc:4FAD8F18AC0BA0A3|rigid:EtN1kLZxdNrob0zGiNWCHVGejS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P12814	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866800|imex:IM-17207-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|entrezgene/locuslink:87(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	intact-crc:C2298AA92E1E011B|rigid:1+ODXMseR/HTS2SyrKMq+/CGcu0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14008	uniprotkb:O00555	intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866939|imex:IM-17207-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|entrezgene/locuslink:9793(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:B20ABB23EEBDE26B|rigid:GO+lXvfIO+M7GSz8oE6qhnv32b8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62158	uniprotkb:O00555	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866929|imex:IM-17207-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O|entrezgene/locuslink:805(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:25711E40C5FDB107|rigid:YT8iYn2R+V40j1oCWx/Y3lmRemU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BXJ1	uniprotkb:O00555	intact:EBI-750200|uniprotkb:Q96NF2|uniprotkb:Q9GZR4|uniprotkb:Q6ZMH6|ensembl:ENSP00000340864|ensembl:ENSP00000343230|ensembl:ENSP00000376240|ensembl:ENSP00000462481|ensembl:ENSP00000462990|ensembl:ENSP00000463008|ensembl:ENSP00000463108|ensembl:ENSP00000463922	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:c1qt1_human(display_long)|uniprotkb:G protein-coupled receptor-interacting protein(gene name synonym)|uniprotkb:C1QTNF1(gene name)|psi-mi:C1QTNF1(display_short)|uniprotkb:CTRP1(gene name synonym)|uniprotkb:UNQ310/PRO353(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866915|imex:IM-17207-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112230.1|refseq:NP_940995.1|refseq:NP_940996.1|refseq:XP_006721729.1|refseq:NP_699203.1|refseq:XP_016879615.1|ensembl:ENSG00000173918(gene)|ensembl:ENST00000339142(transcript)|ensembl:ENST00000354124(transcript)|ensembl:ENST00000392445(transcript)|ensembl:ENST00000579760(transcript)|ensembl:ENST00000580454(transcript)|ensembl:ENST00000580474(transcript)|ensembl:ENST00000581774(transcript)|ensembl:ENST00000583904(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2000860"(positive regulation of aldosterone secretion)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0090331"(negative regulation of platelet aggregation)|entrezgene/locuslink:114897(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:tmtvGTznq5w9Jv8KGg7YGQxQGIE9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:6B31728748EBE3F0|rigid:0Pl/fLROfLJ/qt/llsXpLRiUzuU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q96I11	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3866959	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:q96i11_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866963|imex:IM-17207-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	interpro:IPR030624|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011778(D-hydantoinase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001014809.1|refseq:NP_001304.1|interpro:IPR032466|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|entrezgene/locuslink:1400(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:Kdm/afHEUgaLgy2UUuWJU+NOEKg9606	intact-crc:DF12291288F273F1|rigid:+SH5u6m8IhmyuuacQI48f3ouBx4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:O95153	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-5915931|uniprotkb:O75111|uniprotkb:Q8N5W3|ensembl:ENSP00000345824|intact:EBI-28971165	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:rimb1_human(display_long)|uniprotkb:TSPOAP1(gene name)|psi-mi:TSPOAP1(display_short)|uniprotkb:BZRAP1(gene name synonym)|uniprotkb:KIAA0612(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-interacting protein(gene name synonym)|uniprotkb:RBP1(gene name synonym)|uniprotkb:RIMBP1(gene name synonym)|uniprotkb:RIMS-binding protein 1(gene name synonym)|uniprotkb:TSPO-associated protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866905|imex:IM-17207-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENST00000268893|ensembl:ENSP00000268893|ensembl:ENSP00000345824|refseq:XP_006722236.1|refseq:NP_001248764.1|refseq:NP_004749.2|refseq:NP_077729.1|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|mint:O95153|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-196108|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000005379(gene)|ensembl:ENST00000343736(transcript)|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:9256(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:nOwDlLr5DTjN2tJNR3h0zxrU1Z49606	intact-crc:4B9A4F2B33B1F27F|rigid:IE7L9YftVGWJI3/EztgnuqBOr8s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6IAU3	uniprotkb:O00555	intact:EBI-3866886	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:q6iau3_human(display_long)|uniprotkb:BTG3(gene name)|psi-mi:BTG3(display_short)|uniprotkb:hCG_401161(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866890|imex:IM-17207-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036054|interpro:IPR033332|interpro:IPR002087(Anti-proliferative protein)|refseq:NP_001124386.1|refseq:NP_006797.3|refseq:XP_016883754.1|refseq:XP_016883755.1|entrezgene/locuslink:10950(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:D4NQTe/4OadJ/HmCw/Y/8hqyJg89606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:1EAFECB31E9053DF|rigid:6upzfzOt7Wn8AX7u6qtFv+YCojs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZV1	uniprotkb:O00555	intact:EBI-2835534|uniprotkb:Q7LCQ5|uniprotkb:Q59GH0|uniprotkb:Q9H318|uniprotkb:Q2M2G4|ensembl:ENSP00000280527	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:crim1_human(display_long)|uniprotkb:CRIM1(gene name)|psi-mi:CRIM1(display_short)|uniprotkb:S52(gene name synonym)|uniprotkb:Cysteine-rich repeat-containing protein S52(gene name synonym)|uniprotkb:UNQ1886/PRO4330(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866949|imex:IM-17207-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057525.1|ensembl:ENSG00000150938(gene)|ensembl:ENST00000280527(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR004094(Proteinase inhibitor I15, antistasin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011061(Proteinase inhibitor I14/I15, hirudin/antistatin)|mint:Q9NZV1|go:"GO:0016021"(integral component of membrane)|dip:DIP-58932N|entrezgene/locuslink:51232(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:7oEUkDAWyQgIlQecOcBSn+nnHX49606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:673D33E008EEF649|rigid:hzre7JSGEeusZU+VXTb3SIjyseg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q9HCP6	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-5916693|uniprotkb:Q8TBG3|uniprotkb:Q9ULP7|ensembl:ENSP00000310621|ensembl:ENSP00000405423	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:hhatl_human(display_long)|uniprotkb:HHATL(gene name)|psi-mi:HHATL(display_short)|uniprotkb:C3orf3(gene name synonym)|uniprotkb:GUP1(gene name synonym)|uniprotkb:KIAA1173(gene name synonym)|uniprotkb:Glycerol uptake/transporter homolog(gene name synonym)|uniprotkb:Hedgehog acyltransferase-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867066|imex:IM-17207-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:XP_006713337.1|refseq:NP_065758.3|refseq:XP_016862425.1|ensembl:ENSG00000010282(gene)|ensembl:ENST00000310417(transcript)|ensembl:ENST00000441594(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060262"(negative regulation of N-terminal protein palmitoylation)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR032980|mint:Q9HCP6|entrezgene/locuslink:57467(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:PX1JiW6XVQhNRNoZz5O9H3kqiAM9606	intact-crc:4573F5CD9E044501|rigid:wREfxa0IXO8IuaoZ1ExifiZxejA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P28799	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867053|imex:IM-17207-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N|entrezgene/locuslink:2896(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	intact-crc:BE70CD34AF1980A2|rigid:vh5CCIiTl2bZ3owlULQY/X6O8Vc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23142	uniprotkb:O00555	intact:EBI-726652|uniprotkb:P23143|uniprotkb:P23144|uniprotkb:P37888|uniprotkb:Q5TIC4|uniprotkb:Q8TBH8|uniprotkb:Q9HBQ5|uniprotkb:Q9UC21|uniprotkb:Q9UGR4|uniprotkb:Q9UH41|uniprotkb:B0QY42|intact:EBI-2562209|ensembl:ENSP00000331544|uniprotkb:B1AHL4	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:fbln1_human(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867043|imex:IM-17207-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001987.2|refseq:NP_006476.2|refseq:NP_006477.2|refseq:NP_006478.2|ensembl:ENSG00000077942(gene)|ensembl:ENST00000327858(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071953"(elastic fiber)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904188"(negative regulation of transformation of host cell by virus)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017048(Fibulin-1)|interpro:IPR018097|interpro:IPR026823|mint:P23142|reactome:R-HSA-2129379|go:"GO:0005201"(extracellular matrix structural constituent)|entrezgene/locuslink:2192(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:a47ZJLXWeghGIY9xJTQI7VujuMk9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:D4651D60091E5CB8|rigid:0KV5YLGmmHZBgQdi7HMR8fP2So4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14152	uniprotkb:O00555	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867030|imex:IM-17207-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N|entrezgene/locuslink:8661(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:A6E8CB93EDEA921C|rigid:SWq1kpCfHa9Ge3SdJiVM2KDkrBM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KQ7	uniprotkb:O00555	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867020|imex:IM-17207-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|entrezgene/locuslink:10919(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:7C9E287289DDFD27|rigid:Xa0Vl24DmHBaOiwm4hYInSYtaTI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:O95967	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867010|imex:IM-17207-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	intact-crc:03B6F81359CC4536|rigid:Dj1j1IGBtG5+orD4qZg1irUcFPY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12805	uniprotkb:O00555	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|ensembl:ENSP00000347596|ensembl:ENSP00000378058|uniprotkb:B4DW75	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867000|imex:IM-17207-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115380(gene)|ensembl:ENST00000355426(transcript)|ensembl:ENST00000394555(transcript)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0008083"(growth factor activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR032973|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|entrezgene/locuslink:2202(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:9BFABEA04CAE6FEA|rigid:3Ngoi7UP4dHzTzZi/1mB8sKcbSI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75953	uniprotkb:O00555	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866990|imex:IM-17207-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|entrezgene/locuslink:25822(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:0939483DAB0FC9BD|rigid:WXkfXfkVihVDyDbKXagBvdl2Fjg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P67870	uniprotkb:O00555	intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3866973|imex:IM-17207-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|entrezgene/locuslink:1460(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:447DD14699C51FE2|rigid:sU1C7Dpe0oAOn7cAl1WtMRJFQ4E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60229	uniprotkb:O00555	intact:EBI-949233|ensembl:ENSP00000353109|intact:EBI-1104807|uniprotkb:Q8TBQ5|uniprotkb:Q9NSZ4|uniprotkb:Q9Y2A5|uniprotkb:Q6ZN45|uniprotkb:A8MSI4|uniprotkb:J3QSW6|intact:EBI-3866438|uniprotkb:C9JQ37	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:kalrn_human(display_long)|uniprotkb:KALRN(gene name)|psi-mi:KALRN(display_short)|uniprotkb:DUET(gene name synonym)|uniprotkb:DUO(gene name synonym)|uniprotkb:HAPIP(gene name synonym)|uniprotkb:TRAD(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867130|imex:IM-17207-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036865|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-5687128|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|ensembl:ENSG00000160145(gene)|ensembl:ENST00000360013(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|refseq:NP_001309929.1|refseq:NP_001019831.2|refseq:NP_003938.1|refseq:NP_008995.2|refseq:NP_001309930.1|refseq:NP_001309917.1|refseq:NP_001309918.1|refseq:NP_001309923.1|refseq:NP_001309924.1|refseq:NP_001309925.1|refseq:NP_001309926.1|refseq:NP_001309927.1|refseq:NP_001309928.1|entrezgene/locuslink:8997(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2019/08/05	rogid:E7oPA6ps2iq0KD8jlTCm/mNQj949606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:00B79DB2C9CAB03C|rigid:cClK8+BVZPWJns874/7UD9i8TJE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q76N89	uniprotkb:O00555	intact:EBI-949582|ensembl:ENSP00000379228|uniprotkb:O15036|uniprotkb:Q9HCC7|uniprotkb:A7E2X0|uniprotkb:A8MYS3|uniprotkb:B4DH42|intact:EBI-11059486	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:hecw1_human(display_long)|uniprotkb:HECT, C2 and WW domain-containing protein 1(gene name synonym)|uniprotkb:NEDD4-like E3 ubiquitin-protein ligase 1(gene name synonym)|uniprotkb:HECW1(gene name)|psi-mi:HECW1(display_short)|uniprotkb:KIAA0322(gene name synonym)|uniprotkb:NEDL1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECW1(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867076|imex:IM-17207-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR032348|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|interpro:IPR037795|interpro:IPR040524|mint:Q76N89|rcsb pdb:3L4H|reactome:R-HSA-4641258|ensembl:ENSG00000002746(gene)|ensembl:ENST00000395891(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_055867.3|refseq:NP_001273988.1|refseq:XP_016867375.1|refseq:XP_016867378.1|entrezgene/locuslink:23072(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:iK0wuIJT5WCj76JVf435fZeARkc9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:19211A028D695EC5|rigid:0ZyTS0F1qRaJ54WV+olG997CHQk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75525	uniprotkb:O00555	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867140|imex:IM-17207-80	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:A1623F535F03A3C0|rigid:UgPFX4Xh2rHUeh6VrjAUUn+xHM4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y219	uniprotkb:O00555	intact:EBI-946223|uniprotkb:Q9UE17|uniprotkb:Q9UE99|uniprotkb:Q9UNK8|uniprotkb:Q9Y6P9|uniprotkb:Q9Y6Q0|ensembl:ENSP00000328169	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:jag2_human(display_long)|uniprotkb:JAG2(gene name)|psi-mi:JAG2(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867120|imex:IM-17207-78	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002217.3|refseq:NP_660142.1|ensembl:ENSG00000184916(gene)|ensembl:ENST00000331782(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003016"(respiratory system process)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008083"(growth factor activity)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042492"(gamma-delta T cell differentiation)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:1990134"(epithelial cell apoptotic process involved in palatal shelf morphogenesis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|mint:Q9Y219|rcsb pdb:5MW5|rcsb pdb:5MW7|rcsb pdb:5MWF|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|go:"GO:0005887"(integral component of plasma membrane)|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507|entrezgene/locuslink:3714(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:GoH5Lw1zl+3dhA4RSpJTyQ0LY4Q9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:C9920A681B4A89F7|rigid:XSitDc0/XqJrMtPfrpW+TBtIOWA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q92551	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-751911|uniprotkb:Q7L3I7|uniprotkb:Q96E38|uniprotkb:A8K157|uniprotkb:A8MUX4|ensembl:ENSP00000323780|ensembl:ENSP00000482032	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:ip6k1_human(display_long)|uniprotkb:IP6K1(gene name)|psi-mi:IP6K1(display_short)|uniprotkb:IHPK1(gene name synonym)|uniprotkb:Inositol hexaphosphate kinase 1(gene name synonym)|uniprotkb:KIAA0263(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867106|imex:IM-17207-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001006115.1|refseq:NP_001229758.1|refseq:NP_695005.1|ensembl:ENSG00000176095(gene)|ensembl:ENST00000321599(transcript)|ensembl:ENST00000613416(transcript)|go:"GO:0000827"(inositol-1,3,4,5,6-pentakisphosphate kinase activity)|go:"GO:0000828"(inositol hexakisphosphate kinase activity)|go:"GO:0000829"(inositol heptakisphosphate kinase activity)|go:"GO:0000832"(inositol hexakisphosphate 5-kinase activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0052723"(inositol hexakisphosphate 1-kinase activity)|go:"GO:0052724"(inositol hexakisphosphate 3-kinase activity)|go:"GO:0052836"(inositol 5-diphosphate pentakisphosphate 5-kinase activity)|go:"GO:0052839"(inositol diphosphate tetrakisphosphate kinase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR005522(Inositol polyphosphate kinase)|reactome:R-HSA-1855167|reactome:R-HSA-1855191|entrezgene/locuslink:9807(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:VbkyLVoXEkuiIKBTA1Llj8keyeE9606	intact-crc:76B3277C1234CA0E|rigid:XPZfoPMsA3e9OQelDoHIj15004o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98160	uniprotkb:O00555	intact:EBI-947664|uniprotkb:Q16287|uniprotkb:Q9H3V5|uniprotkb:Q5SZI3|ensembl:ENSP00000363827	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:pgbm_human(display_long)|uniprotkb:Perlecan(gene name synonym)|uniprotkb:HSPG2(gene name)|psi-mi:HSPG2(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867096|imex:IM-17207-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278789.1|refseq:NP_005520.4|ensembl:ENSG00000142798(gene)|ensembl:ENST00000374695(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0030154"(cell differentiation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072359"(circulatory system development)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR000034(Laminin B)|interpro:IPR000082(SEA)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR023415|interpro:IPR036055|interpro:IPR036179|mint:P98160|rcsb pdb:3SH4|rcsb pdb:3SH5|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|reactome:R-HSA-977225|entrezgene/locuslink:3339(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:5ctWru2Fde+1Twjd9B7u24hsIKY9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:E9A15E94A88483D9|rigid:gG5lbTDvml0EjIo1XSTvfUHSujM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15822	uniprotkb:O00555	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867086|imex:IM-17207-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002105.3|ensembl:ENSG00000095951(gene)|ensembl:ENST00000379388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|entrezgene/locuslink:3096(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:rugwzqsTO0X8mJ5Zy3msTqc6dr09606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:03EB9BA35DEB6486|rigid:AOf+NxPtfioxIZon+IitJzpYQ0c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A73	uniprotkb:O00555	intact:EBI-725897|uniprotkb:B8K1S6|uniprotkb:Q8NDU3|uniprotkb:Q9BRE5|uniprotkb:Q9H7D5|uniprotkb:Q9ULM9|uniprotkb:Q6IA24|uniprotkb:B2RD69|ensembl:ENSP00000298569|ensembl:ENSP00000421061	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:p33mx_human(display_long)|uniprotkb:KIAA1191(gene name)|psi-mi:KIAA1191(display_short)|uniprotkb:Brain-derived rescue factor p60MONOX(gene name synonym)|uniprotkb:P33MONOX(gene name synonym)|uniprotkb:Flavin monooxygenase motif-containing protein of 33 kDa(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867163|imex:IM-17207-82	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073152.1|refseq:NP_001073153.1|refseq:NP_065177.2|refseq:NP_001274264.1|refseq:NP_001274265.1|refseq:XP_005265998.1|refseq:XP_005266003.1|ensembl:ENSG00000122203(gene)|ensembl:ENST00000298569(transcript)|ensembl:ENST00000510164(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR026759|entrezgene/locuslink:57179(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:ifBPsTNia/Yd27cRSNHVYm6h8H49606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:BE718C92881D7AE3|rigid:8yfnsJuK30Bv7bWqH+Rd6eJYONw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A7MD48	uniprotkb:O00555	intact:EBI-3867173|uniprotkb:Q7Z5F0|uniprotkb:B2RZH7|uniprotkb:Q96JH4|uniprotkb:A8K5P6|ensembl:ENSP00000267260	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:srrm4_human(display_long)|uniprotkb:SRRM4(gene name)|psi-mi:SRRM4(display_short)|uniprotkb:KIAA1853(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-2.76(gene name synonym)|uniprotkb:Neural-specific serine/arginine repetitive splicing factor of 100 kDa(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867181|imex:IM-17207-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_919262.2|ensembl:ENSG00000139767(gene)|ensembl:ENST00000267260(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008380"(RNA splicing)|go:"GO:0030154"(cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR029360|entrezgene/locuslink:84530(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:QfC69szB3vSzJoIoh6krII+mr049606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:0946A15F7C15BCCF|rigid:kahV7ITCJBruQsqxZQX3YRKr1t4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q8TAS6	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-2622017	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:q8tas6_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867191|imex:IM-17207-84	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	interpro:IPR002049(EGF-like, laminin)|interpro:IPR013015(Laminin IV)|refseq:NP_002282.2|interpro:IPR000742(EGF-like, type 3)|entrezgene/locuslink:3912(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:HCEb+we2ZRZClQiN5+RQx/CcT7g9606	intact-crc:D66A4CBFE91A0C25|rigid:MdKSpAyqp1rC4wnkQ/bkMIoprMo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07954	uniprotkb:O00555	intact:EBI-1046087|uniprotkb:Q8IVG8|uniprotkb:Q2PP12|uniprotkb:Q86SW0|ensembl:ENSP00000243077	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:lrp1_human(display_long)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:Apolipoprotein E receptor(gene name synonym)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:A2MR(gene name synonym)|uniprotkb:APR(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867221|imex:IM-17207-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002323.2|ensembl:ENSG00000123384(gene)|ensembl:ENST00000243077(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002020"(protease binding)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016964"(alpha-2 macroglobulin receptor activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030226"(apolipoprotein receptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032370"(positive regulation of lipid transport)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048694"(positive regulation of collateral sprouting of injured axon)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904300"(positive regulation of transcytosis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905049"(negative regulation of metallopeptidase activity)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|rcsb pdb:1CR8|rcsb pdb:1D2L|rcsb pdb:1J8E|rcsb pdb:2FYJ|rcsb pdb:2FYL|rcsb pdb:2KNX|rcsb pdb:2KNY|reactome:R-HSA-2168880|reactome:R-HSA-975634|dip:DIP-50613N|entrezgene/locuslink:4035(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:eO2l3huuq6NYoVoYdoCloLqrlRw9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:2A0DCE123C68D880|rigid:YEnuLDQJ/t6rGyFF4u46PgO9RUY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94910	uniprotkb:O00555	intact:EBI-3389315|uniprotkb:Q9BU07|uniprotkb:Q9HAR3|uniprotkb:Q96IE7|ensembl:ENSP00000340688|ensembl:ENSP00000500240	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:agrl1_human(display_long)|uniprotkb:ADGRL1(gene name)|psi-mi:ADGRL1(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 1(gene name synonym)|uniprotkb:KIAA0821(gene name synonym)|uniprotkb:LEC2(gene name synonym)|uniprotkb:LPHN1(gene name synonym)|uniprotkb:Latrophilin-1(gene name synonym)|uniprotkb:Lectomedin-2(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867211|imex:IM-17207-86	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008701.1|refseq:NP_055736.2|ensembl:ENSG00000072071(gene)|ensembl:ENSG00000288324(gene)|ensembl:ENST00000340736(transcript)|ensembl:ENST00000672190(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016524"(latrotoxin receptor activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090129"(positive regulation of synapse maturation)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR031234|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|mint:O94910|entrezgene/locuslink:22859(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:kHETaGfz/t0XytDX2HWU7/xty589606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:45A5E813E8885536|rigid:tust5Bwpz5hC8O8kdskDgqPIOn4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q15334	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-299979|ensembl:ENSP00000321537|ensembl:ENSP00000492144|uniprotkb:O00188|uniprotkb:Q58F11|uniprotkb:Q86UK6|uniprotkb:A7MBM7	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:l2gl1_human(display_long)|uniprotkb:DLG4(gene name synonym)|uniprotkb:LLGL1(gene name)|psi-mi:LLGL1(display_short)|uniprotkb:Human homolog to the D-lgl gene protein(gene name synonym)|uniprotkb:Hugl-1(gene name synonym)|uniprotkb:HUGL(gene name synonym)|uniprotkb:HUGL1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867201|imex:IM-17207-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENSG00000131899(gene)|ensembl:ENSG00000284137(gene)|ensembl:ENST00000316843(transcript)|ensembl:ENST00000640494(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0000137"(Golgi cis cisterna)|mint:Q15334|refseq:NP_004131.3|entrezgene/locuslink:3996(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:VqlrgKVnWmXyx1lvnpRe9hRQD0Q9606	intact-crc:304B6AF35CD9E99F|rigid:bnxGyox2Gepc1unYsWaJitP3LGY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y4R8	uniprotkb:O00555	intact:EBI-1043674|uniprotkb:O75168|uniprotkb:Q7LDV4|uniprotkb:Q9BR21|intact:EBI-725566|intact:EBI-1047721|ensembl:ENSP00000262319|uniprotkb:D3DU73	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:telo2_human(display_long)|uniprotkb:TELO2(gene name)|psi-mi:TELO2(display_short)|uniprotkb:KIAA0683(gene name synonym)|uniprotkb:Protein clk-2 homolog(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867153|imex:IM-17207-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100726(gene)|ensembl:ENST00000262319(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070209"(ASTRA complex)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019337|interpro:IPR038528|mint:Q9Y4R8|rcsb pdb:4PSI|refseq:NP_057195.2|refseq:XP_016879403.1|dip:DIP-40568N|entrezgene/locuslink:9894(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:AnKk5b5Bc/tzEEz+p68m5uQUZVY9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:F694C14D08DB63EC|rigid:Nt2y0tN2qiP6IVHCX+jktXlUp2U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:O75095	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-947597|uniprotkb:Q5VV39|uniprotkb:Q4AC86|ensembl:ENSP00000348982	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:megf6_human(display_long)|uniprotkb:MEGF6(gene name)|psi-mi:MEGF6(display_short)|uniprotkb:EGFL3(gene name synonym)|uniprotkb:KIAA0815(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867311|imex:IM-17207-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001400.3|ensembl:ENSG00000162591(gene)|ensembl:ENST00000356575(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|mint:O75095|entrezgene/locuslink:1953(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:/4HcLiv4UEW2qmvoV2OTj110y1I9606	intact-crc:E1666D235F0083AC|rigid:zzfkky90zXuVCRqznxwwxADv1ik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:O00339	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-949020|uniprotkb:A8K106|uniprotkb:E7EW74|uniprotkb:E9PD48|uniprotkb:E9PGL2|ensembl:ENSP00000254898|ensembl:ENSP00000430487|uniprotkb:Q6UWA5|uniprotkb:Q7Z5X1|uniprotkb:Q8NDE6|uniprotkb:Q96FT5|uniprotkb:Q9NSZ1	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:matn2_human(display_long)|uniprotkb:MATN2(gene name)|psi-mi:MATN2(display_short)|uniprotkb:UNQ193/PRO219(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867301|imex:IM-17207-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	dip:DIP-47267N|ensembl:ENSG00000132561(gene)|ensembl:ENST00000254898(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0031012"(extracellular matrix)|ensembl:ENST00000520016(transcript)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019466|interpro:IPR026823|interpro:IPR030747|interpro:IPR036337|interpro:IPR036465|refseq:NP_002371.3|refseq:NP_085072.2|refseq:NP_001304677.1|entrezgene/locuslink:4147(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:umvJixncdhOkQvywPNFjPo1Aqx89606	intact-crc:7613AA6008B7D60E|rigid:Qb0NKX9bXmRAoEta4YUD6VlWkQA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42679	uniprotkb:O00555	intact:EBI-751664|uniprotkb:B3KNZ9|uniprotkb:Q9NST8|ensembl:ENSP00000308734	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:matk_human(display_long)|uniprotkb:Tyrosine-protein kinase CTK(gene name synonym)|uniprotkb:Protein kinase HYL(gene name synonym)|uniprotkb:Hematopoietic consensus tyrosine-lacking kinase(gene name synonym)|uniprotkb:MATK(gene name)|psi-mi:MATK(display_short)|uniprotkb:CTK(gene name synonym)|uniprotkb:HYL(gene name synonym)|uniprotkb:CSK homologous kinase(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867291|imex:IM-17207-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002369.2|refseq:NP_647611.1|refseq:NP_647612.1|refseq:XP_011526320.1|ensembl:ENSG00000007264(gene)|ensembl:ENST00000310132(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|rcsb pdb:1JWO|rcsb pdb:1X6G|rcsb pdb:3US4|reactome:R-HSA-8863795|entrezgene/locuslink:4145(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:zA5Bl6NIDDz31AJcm6u02v4bEe89606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:E20C56D00B21E441|rigid:IC8eEM6Dr0QMMoSf9IvEn31dlrY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q9NQG1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3867271|uniprotkb:E1P5V3|uniprotkb:A8KAA6|ensembl:ENSP00000362707|ensembl:ENSP00000362708|ensembl:ENSP00000380338|ensembl:ENSP00000380339	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:manbl_human(display_long)|uniprotkb:MANBAL(gene name)|psi-mi:MANBAL(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867277|imex:IM-17207-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001003897.1|refseq:NP_071360.1|ensembl:ENSG00000101363|ensembl:ENSG00000101363(gene)|ensembl:ENST00000373605(transcript)|ensembl:ENST00000373606(transcript)|ensembl:ENST00000397151(transcript)|ensembl:ENST00000397152(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009621(Protein of unknown function UPF0239)|refseq:XP_016883495.1|refseq:XP_016883496.1|entrezgene/locuslink:63905(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:fOa7GCKnwAkiQu80yEwrZMZzKqU9606	intact-crc:873687B008E9F3B3|rigid:aQw6FBxOmZGZTsO15o53oFfIgt0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q8N2S1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867261|imex:IM-17207-90	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379|entrezgene/locuslink:8425(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:ADC6F176C4054BE5|rigid:jD0tWaUoAjkBjOfanegVptl/9Ww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:B9EG76	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3867246	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:b9eg76_human(display_long)|uniprotkb:LTBP3(gene name)|psi-mi:LTBP3(display_short)|uniprotkb:hCG_1812642(orf name)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867251|imex:IM-17207-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	interpro:IPR036773|interpro:IPR026823|interpro:IPR009030(Growth factor, receptor)|refseq:NP_001157738.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR017878|go:"GO:0005509"(calcium ion binding)|entrezgene/locuslink:4054(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:3QOpxa7LURr8Uo23Ln80hjTFvkA9606	intact-crc:4305101459BCC67D|rigid:hj2iMyhQWg62pmVyHPyB0i8n9es	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:B7ZLY3	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3867233	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:b7zly3_human(display_long)|uniprotkb:LTBP1(gene name)|psi-mi:LTBP1(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867231|imex:IM-17207-88	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	interpro:IPR036773|interpro:IPR009030(Growth factor, receptor)|refseq:NP_001159736.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR017878|go:"GO:0001527"(microfibril)|go:"GO:0005509"(calcium ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050436"(microfibril binding)|interpro:IPR026823|entrezgene/locuslink:4052(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:Hyyq4Yzw1JhmNuy1eAOsOV+gB749606	intact-crc:21E93449CE28E559|rigid:vzma0IyfBEXmrLnGIslQUAHttJ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z7M0	uniprotkb:O00555	intact:EBI-947617|uniprotkb:O75097|uniprotkb:A8KAY0|ensembl:ENSP00000251268	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:megf8_human(display_long)|uniprotkb:MEGF8(gene name)|psi-mi:MEGF8(display_short)|uniprotkb:EGFL4(gene name synonym)|uniprotkb:KIAA0817(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 4(gene name synonym)|uniprotkb:C19orf49(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867321|imex:IM-17207-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001401.2|refseq:NP_001258867.1|ensembl:ENSG00000105429(gene)|ensembl:ENST00000251268(transcript)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0055113"(epiboly involved in gastrulation with mouth forming second)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0097155"(fasciculation of sensory neuron axon)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016201(Plexin-like fold)|interpro:IPR018097|interpro:IPR024731|interpro:IPR035914|mint:Q7Z7M0|go:"GO:0048704"(embryonic skeletal system morphogenesis)|entrezgene/locuslink:1954(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:NaA9e3P2Wh8y5vrZQQPOYHh8ogc9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:F0344819CEBDA5EA|rigid:4jxWuLtC4w4luq2vIZmPqOT3U/U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JRA6	uniprotkb:O00555	intact:EBI-2291868|uniprotkb:A8K2S0|uniprotkb:A8MT05|uniprotkb:A8MT13|uniprotkb:B7Z430|uniprotkb:Q3S4X3|uniprotkb:Q5JRB0|uniprotkb:Q14083|uniprotkb:Q5JRA5|uniprotkb:Q5JRB1|uniprotkb:Q5JRB2|uniprotkb:Q6UVY8|uniprotkb:Q86Y60|uniprotkb:Q8N8M5|uniprotkb:Q92580|intact:EBI-2803073|ensembl:ENSP00000340900	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:tgo1_human(display_long)|uniprotkb:TANGO(gene name synonym)|uniprotkb:MIA3(gene name)|psi-mi:MIA3(display_short)|uniprotkb:KIAA0268(gene name synonym)|uniprotkb:C219-reactive peptide(gene name synonym)|uniprotkb:D320(gene name synonym)|uniprotkb:UNQ6077/PRO20088(orf name)|uniprotkb:Melanoma inhibitory activity protein 3(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867346|imex:IM-17207-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940953.2|refseq:NP_001287796.1|ensembl:ENSG00000154305(gene)|ensembl:ENST00000344922(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|refseq:NP_001310992.1|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:2000402"(negative regulation of lymphocyte migration)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275|entrezgene/locuslink:375056(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:DGy7mQTlQIbcaklbpG7jmdj9G/I9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:53192662CEED9437|rigid:reR9Ghn2NHnQScLe5Qs3u7+8qHQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q96BY2	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-739825|uniprotkb:Q9H833|uniprotkb:Q9HAS1|uniprotkb:B2RDF6|ensembl:ENSP00000298894|ensembl:ENSP00000451594|ensembl:ENSP00000482284|ensembl:ENSP00000486260	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:moap1_human(display_long)|uniprotkb:MOAP1(gene name)|psi-mi:MOAP1(display_short)|uniprotkb:PNMA4(gene name synonym)|uniprotkb:Paraneoplastic antigen Ma4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867356|imex:IM-17207-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_071434.2|ensembl:ENST00000627896(transcript)|go:"GO:0001844"(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENSG00000165943(gene)|ensembl:ENSG00000278268(gene)|ensembl:ENST00000298894(transcript)|ensembl:ENST00000556883(transcript)|ensembl:ENST00000616515(transcript)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR026523|mint:Q96BY2|go:"GO:0005829"(cytosol)|dip:DIP-49959N|entrezgene/locuslink:64112(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:wQSSosC82m35M8s+YamN1i73wi49606	intact-crc:9EEBAD4288752BBD|rigid:cUvrBZAhlNPui3pWs/B67UjvokE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95169	uniprotkb:O00555	intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867366|imex:IM-17207-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1|entrezgene/locuslink:4714(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:6596FD935B46EC24|rigid:GDjMVd7h2h4JoC358sDDL0z2woA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99435	uniprotkb:O00555	intact:EBI-946274|intact:EBI-2845314|uniprotkb:B7Z2U7|uniprotkb:B7Z5Q4|uniprotkb:B7Z9J5|uniprotkb:B7Z9U3|uniprotkb:Q96JS2|ensembl:ENSP00000390680|ensembl:ENSP00000394612	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:nell2_human(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867386|imex:IM-17207-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138579.1|refseq:NP_001138580.1|refseq:NP_001138581.1|refseq:NP_001138582.1|refseq:NP_006150.1|refseq:XP_011536698.1|refseq:XP_005268962.1|dip:DIP-49927N|ensembl:ENSG00000184613(gene)|ensembl:ENST00000429094(transcript)|ensembl:ENST00000452445(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0008201"(heparin binding)|go:"GO:0070050"(neuron cellular homeostasis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|mint:Q99435|rcsb pdb:6POG|reactome:R-HSA-428542|entrezgene/locuslink:4753(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:4EEF48C288767EDE|rigid:BIWuLsuaIacUKMusgc850nGebcw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92832	uniprotkb:O00555	intact:EBI-947754|uniprotkb:Q4VB91|uniprotkb:Q4VB90|uniprotkb:B2CKC1|uniprotkb:Q9Y472|uniprotkb:Q6NSY8|ensembl:ENSP00000349654	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:nell1_human(display_long)|uniprotkb:NEL-like protein 1(gene name synonym)|uniprotkb:Nel-related protein 1(gene name synonym)|uniprotkb:NELL1(gene name)|psi-mi:NELL1(display_short)|uniprotkb:NRP1(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867376|imex:IM-17207-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006148.2|refseq:NP_963845.1|refseq:NP_001275642.1|refseq:NP_001275643.1|ensembl:ENSG00000165973(gene)|ensembl:ENST00000357134(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR024731|mint:Q92832|rcsb pdb:6POL|entrezgene/locuslink:4745(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:nC7vtd2PeL7K7QjSVJDoDJE3owk9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:B4ECA25C46AE4AB3|rigid:5PqKRPXKMwJ9SggxqktcvOT5oHo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:A8MQ03	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3867333|uniprotkb:Q86UY7|ensembl:ENSP00000498316	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:crtp1_human(display_long)|uniprotkb:CYSRT1(gene name)|psi-mi:CYSRT1(display_short)|uniprotkb:C9orf169(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867331|imex:IM-17207-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_945352.3|ensembl:ENSG00000197191(gene)|ensembl:ENST00000650725(transcript)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR018904|entrezgene/locuslink:375791(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:xplFfCUdFvm6d/hwQ6jwKhgkK589606	intact-crc:BB9B0FF8B5514FB2|rigid:l8jWFA1h2unXD4nfCMXMiGMHszE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P46531	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867396|imex:IM-17207-102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_060087.3|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0005912"(adherens junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|go:"GO:0070986"(left/right axis specification)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR035993|interpro:IPR036770|mint:P46531|rcsb pdb:1PB5|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000148400(gene)|ensembl:ENST00000651671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|dip:DIP-29919N|ensembl:ENSP00000498587|entrezgene/locuslink:4851(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:3C6A2C528F02351B|rigid:HqmxeslC5GE3Pvm+yyLynvbFUNk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UR1	uniprotkb:O00555	intact:EBI-949814|ensembl:ENSP00000507846|uniprotkb:O60533|uniprotkb:Q29VU9|uniprotkb:Q29VV0|uniprotkb:Q2TAM1|uniprotkb:Q8IUS3	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:noxa1_human(display_long)|uniprotkb:NCF2-like protein(gene name synonym)|uniprotkb:Antigen NY-CO-31(gene name synonym)|uniprotkb:P67phox-like factor(gene name synonym)|uniprotkb:p51-nox(gene name synonym)|uniprotkb:NOXA1(gene name)|psi-mi:NOXA1(display_short)|uniprotkb:P51NOX(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867406|imex:IM-17207-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188747(gene)|ensembl:ENST00000683555(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0060263"(regulation of respiratory burst)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034899|interpro:IPR036028|reactome:R-HSA-5668599|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9673324|refseq:NP_006638.1|refseq:NP_001242996.1|refseq:NP_001242997.1|entrezgene/locuslink:10811(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:b9yF3AbB0i4feLHukYPjiT5jlJg9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:2F7AF552885F28DC|rigid:BSMHesX/zfy72sa2sEDJ4aMZrf4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92824	uniprotkb:O00555	intact:EBI-751290|uniprotkb:Q13527|intact:EBI-947942|uniprotkb:Q96EP4|uniprotkb:F5H2G7|ensembl:ENSP00000446280	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:pcsk5_human(display_long)|uniprotkb:Subtilisin/kexin-like protease PC5(gene name synonym)|uniprotkb:PCSK5(gene name)|psi-mi:PCSK5(display_short)|uniprotkb:PC5(gene name synonym)|uniprotkb:PC6(gene name synonym)|uniprotkb:Proprotein convertase 5(gene name synonym)|uniprotkb:Proprotein convertase 6(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867431|imex:IM-17207-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177411.1|refseq:NP_006191.2|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0019058"(viral life cycle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030323"(respiratory tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042277"(peptide binding)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051004"(regulation of lipoprotein lipase activity)|go:"GO:0140447"(cytokine precursor processing)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR006212(Furin-like repeat)|ensembl:ENSG00000099139(gene)|ensembl:ENST00000545128(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006465"(signal peptide processing)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008233"(peptidase activity)|go:"GO:0009952"(anterior/posterior pattern specification)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032778|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|reactome:R-HSA-167060|reactome:R-HSA-8963889|entrezgene/locuslink:5125(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:5e1gFIyzA+oooSthhUnV8rid4Ms9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:A963DEA049599DA3|rigid:+cKlVJyEhox8f6pI4YILJos1lFU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P29122	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-2683528|uniprotkb:Q9UEJ8|uniprotkb:Q9UEJ9|uniprotkb:Q15100|uniprotkb:Q9Y4H1|uniprotkb:Q9UEJ1|uniprotkb:Q9Y4H0|uniprotkb:Q9UEJ2|uniprotkb:Q15099|uniprotkb:Q9UEJ7|uniprotkb:Q9Y4G9|uniprotkb:Q9UEG7|ensembl:ENSP00000482760	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:pcsk6_human(display_long)|uniprotkb:PACE4(gene name synonym)|uniprotkb:Paired basic amino acid cleaving enzyme 4(gene name synonym)|uniprotkb:Subtilisin-like proprotein convertase 4(gene name synonym)|uniprotkb:Subtilisin/kexin-like protease PACE4(gene name synonym)|uniprotkb:PCSK6(gene name)|psi-mi:PCSK6(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867441|imex:IM-17207-106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_002561.1|refseq:NP_612192.1|refseq:NP_612195.1|refseq:NP_612196.1|refseq:NP_612197.1|refseq:NP_001278238.1|refseq:NP_612198.2|ensembl:ENSG00000140479(gene)|ensembl:ENST00000611716(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008201"(heparin binding)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0032902"(nerve growth factor production)|go:"GO:0032940"(secretion by cell)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0051004"(regulation of lipoprotein lipase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010909(PLAC)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032778|interpro:IPR032815|interpro:IPR034182|interpro:IPR038466|reactome:R-HSA-1181150|reactome:R-HSA-167060|reactome:R-HSA-6809371|reactome:R-HSA-8963889|interpro:IPR036852|dip:DIP-29903N|entrezgene/locuslink:5046(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:Xh7YAAyyc+G8pX8aiioRKS4PB/Y9606	intact-crc:CF249E941C3B674B|rigid:BWcvn4OV4Ww/3sm68ULuMDaDBsQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92871	uniprotkb:O00555	intact:EBI-746784|uniprotkb:Q92586|ensembl:ENSP00000216259|uniprotkb:A8K003	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:pmm1_human(display_long)|uniprotkb:PMMH-22(gene name synonym)|uniprotkb:PMM1(gene name)|psi-mi:PMM1(display_short)|uniprotkb:PMMH22(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867451|imex:IM-17207-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002667.2|ensembl:ENSG00000100417(gene)|ensembl:ENST00000216259(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR005002(Eukaryotic phosphomannomutase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|interpro:IPR043169|rcsb pdb:2FUC|rcsb pdb:2FUE|rcsb pdb:6CFR|rcsb pdb:6CFS|rcsb pdb:6CFT|rcsb pdb:6CFU|rcsb pdb:6CFV|reactome:R-HSA-446205|entrezgene/locuslink:5372(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:81dnT3cBTmay4gBImF2JF9oyrr09606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:FB11AEA048F35B78|rigid:gQr2csKD4iQH2S+Q9byZYOi1/jA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13427	uniprotkb:O00555	intact:EBI-396072|uniprotkb:O00706|uniprotkb:Q96DG9|uniprotkb:Q53R40|uniprotkb:Q53SN4|ensembl:ENSP00000260970|ensembl:ENSP00000407083|ensembl:ENSP00000408683|ensembl:ENSP00000502997|ensembl:ENSP00000503136|ensembl:ENSP00000503525|uniprotkb:D3DPC5|uniprotkb:D3DPC6	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:ppig_human(display_long)|uniprotkb:PPIG(gene name)|psi-mi:PPIG(display_short)|uniprotkb:Cyclophilin G(gene name synonym)|uniprotkb:Clk-associating RS-cyclophilin(gene name synonym)|uniprotkb:CASP10(gene name synonym)|uniprotkb:Rotamase G(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867461|imex:IM-17207-108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004783.2|ensembl:ENSG00000138398(gene)|ensembl:ENST00000260970(transcript)|ensembl:ENST00000433207(transcript)|ensembl:ENST00000448752(transcript)|ensembl:ENST00000676756(transcript)|ensembl:ENST00000678499(transcript)|ensembl:ENST00000679107(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:Q13427|rcsb pdb:2GW2|rcsb pdb:2WFI|rcsb pdb:2WFJ|rcsb pdb:5YZG|go:"GO:0006457"(protein folding)|refseq:XP_005247023.1|refseq:XP_005247024.1|entrezgene/locuslink:9360(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:gp1Pqv5G8E+PrPmp+BtUSSIkD/89606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:4F9BD9E0FC40BB55|rigid:9o6ojP66Zwzxh9ELu284u7iqSQU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BZL4	uniprotkb:O00555	intact:EBI-721802|uniprotkb:Q59FK8|uniprotkb:Q6ZPD1|uniprotkb:Q7L8F7|uniprotkb:Q9H5H5|uniprotkb:Q9NT00|uniprotkb:Q96HW1|uniprotkb:B4DME2|ensembl:ENSP00000263433	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:pp12c_human(display_long)|uniprotkb:LENG3(gene name synonym)|uniprotkb:MBS85(gene name synonym)|uniprotkb:Protein phosphatase 1 myosin-binding subunit of 85 kDa(gene name synonym)|uniprotkb:PPP1R12C(gene name)|psi-mi:PPP1R12C(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867471|imex:IM-17207-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060077.1|refseq:NP_001258547.1|refseq:XP_005259070.1|ensembl:ENSG00000125503(gene)|ensembl:ENST00000263433(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031205|interpro:IPR031775|interpro:IPR036770|mint:Q9BZL4|entrezgene/locuslink:54776(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:q24mbt02IydCWtQyNXmNVWav/i89606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:D942D3E74941BCE1|rigid:bJV0AZ2beunSG4QWBWy36QxJL+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAK6	uniprotkb:O00555	intact:EBI-3867416|uniprotkb:Q7RTS0|ensembl:ENSP00000371785	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:olig1_human(display_long)|uniprotkb:OLIG1(gene name)|psi-mi:OLIG1(display_short)|uniprotkb:BHLHB6(gene name synonym)|uniprotkb:BHLHE21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 6(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 21(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867421|imex:IM-17207-104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620450.2|ensembl:ENSG00000184221(gene)|ensembl:ENST00000382348(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q8TAK6|entrezgene/locuslink:116448(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:6zU+GDe1CfmWRzr5E6Bx5NzmLoY9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:1664CCBFE91EC501|rigid:Hea2BhVSKTfPTihyXqdQPB0zs1M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q8IXT5	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3044077|ensembl:ENSP00000382239|ensembl:ENSP00000427729|ensembl:ENSP00000428269|ensembl:ENSP00000429807|ensembl:ENSP00000430474|uniprotkb:A8MYB5	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:rb12b_human(display_long)|uniprotkb:RBM12B(gene name)|psi-mi:RBM12B(display_short)|uniprotkb:RNA-binding motif protein 12B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867491|imex:IM-17207-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:XP_016868895.1|refseq:XP_016868896.1|refseq:XP_016868897.1|ensembl:ENSG00000183808(gene)|ensembl:ENST00000399300(transcript)|ensembl:ENST00000517700(transcript)|ensembl:ENST00000518597(transcript)|ensembl:ENST00000519109(transcript)|ensembl:ENST00000520560(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034588|interpro:IPR034858|interpro:IPR035979|refseq:XP_011515329.1|refseq:XP_011515330.1|refseq:XP_011515331.1|refseq:NP_976324.2|refseq:XP_005250972.1|entrezgene/locuslink:389677(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:WFJYO2tbSpgVmVVnSyFLn4O2+HM9606	intact-crc:BEB9528319826959|rigid:Cr01/5x2xWGuBErgwmmVHPJBt+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:O15034	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-2512648|intact:EBI-28983594|ensembl:ENSP00000261655|uniprotkb:Q96ID2	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:rimb2_human(display_long)|uniprotkb:RIMBP2(gene name)|psi-mi:RIMBP2(display_short)|uniprotkb:KIAA0318(gene name synonym)|uniprotkb:RBP2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867501|imex:IM-17207-112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENSG00000060709(gene)|ensembl:ENST00000261655(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035519|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:1WIE|rcsb pdb:2CSI|rcsb pdb:2CSP|rcsb pdb:2CSQ|ensembl:ENSP00000261655|refseq:NP_056162.4|entrezgene/locuslink:23504(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:poJ/MI+hMdizT9v0sb3u5blhZgY9606	intact-crc:004C8D235CD4C906|rigid:ZRN4xn/MbD7p129uujndfa+yQhY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P62899	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867515|imex:IM-17207-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|entrezgene/locuslink:6160(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:77LFR7/2somk6blVogZf1XFdJLk9606	intact-crc:215376C9CE587FD9|rigid:V1d/EiIDQEOMBcXJ+BYVg7aHsds	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08708	uniprotkb:O00555	intact:EBI-358255|uniprotkb:B2R4U4|intact:EBI-8012092|intact:EBI-11603362|intact:MINT-8395037|uniprotkb:P0CW22|ensembl:ENSP00000483755|ensembl:ENSP00000498019	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:rs17_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short)|uniprotkb:Small ribosomal subunit protein eS17(gene name synonym)|uniprotkb:RPS17L(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867525|imex:IM-17207-114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012.1|ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000617731(transcript)|ensembl:ENST00000647841(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P08708|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|go:"GO:0034101"(erythrocyte homeostasis)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|entrezgene/locuslink:6218(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:st+xQCXdSObiy6cJD1cSx869V289606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:9E4FFD34AE0D532C|rigid:XzaDeTYHiauwXylJsi/C5446Pn8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22307	uniprotkb:O00555	intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|ensembl:ENSP00000360569|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867535|imex:IM-17207-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180528.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_002970.2|ensembl:ENSG00000116171(gene)|ensembl:ENST00000371514(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032385"(positive regulation of intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0032959"(inositol trisphosphate biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033814"(propanoyl-CoA C-acyltransferase activity)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045940"(positive regulation of steroid metabolic process)|go:"GO:0050632"(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|go:"GO:0070538"(oleic acid binding)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1901373"(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|interpro:IPR036527|mint:P22307|rcsb pdb:1QND|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|rcsb pdb:2C0L|refseq:XP_016857535.1|refseq:NP_001007099.1|refseq:NP_001180546.1|entrezgene/locuslink:6342(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:1A8A89A41C111498|rigid:egwx0l6Yjc/cYUs/hQOeFZAwqAk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P41222	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-948821|ensembl:ENSP00000360687|uniprotkb:Q9UC22|uniprotkb:Q5SQ10|uniprotkb:Q7M4P3|uniprotkb:Q9UCC9|uniprotkb:Q9UCD9|uniprotkb:B2R727	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:ptgds_human(display_long)|uniprotkb:Lipocalin-type prostaglandin-D synthase(gene name synonym)|uniprotkb:Glutathione-independent PGD synthase(gene name synonym)|uniprotkb:Prostaglandin-D2 synthase(gene name synonym)|uniprotkb:Beta-trace protein(gene name synonym)|uniprotkb:Cerebrin-28(gene name synonym)|uniprotkb:PTGDS(gene name)|psi-mi:PTGDS(display_short)|uniprotkb:PDS(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867481|imex:IM-17207-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENSG00000107317(gene)|ensembl:ENST00000371625(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0004667"(prostaglandin-D synthase activity)|go:"GO:0005501"(retinoid binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036094"(small molecule binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR002972(Prostaglandin D synthase)|interpro:IPR012674(Calycin)|interpro:IPR022272|mint:P41222|rcsb pdb:2WWP|rcsb pdb:3O19|rcsb pdb:3O22|rcsb pdb:3O2Y|rcsb pdb:4IMN|rcsb pdb:4IMO|rcsb pdb:4ORR|rcsb pdb:4ORS|rcsb pdb:4ORU|rcsb pdb:4ORW|rcsb pdb:4ORX|rcsb pdb:4ORY|rcsb pdb:4OS0|rcsb pdb:4OS3|rcsb pdb:4OS8|rcsb pdb:5WY9|reactome:R-HSA-2162123|reactome:R-HSA-9690406|refseq:NP_000945.3|entrezgene/locuslink:5730(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:hqvCVc1a1AWLCZWiYWgA4vPZNtk9606	intact-crc:06BA9F419F9B67D1|rigid:DbNV7oNQZjvqikYoUchHgvskm7w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15714	uniprotkb:O00555	intact:EBI-712609|uniprotkb:O00666|uniprotkb:Q6AHX5|uniprotkb:Q96JS5|ensembl:ENSP00000397435|uniprotkb:Q8NCN1|intact:EBI-1223414|uniprotkb:Q6IBU1|intact:EBI-3448913|uniprotkb:B9EGI0|uniprotkb:B3KRL7	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:t22d1_human(display_long)|uniprotkb:TSC22D1(gene name)|psi-mi:TSC22D1(display_short)|uniprotkb:KIAA1994(gene name synonym)|uniprotkb:TGFB1I4(gene name synonym)|uniprotkb:TSC22(gene name synonym)|uniprotkb:Transforming growth factor beta-1-induced transcript 4 protein(gene name synonym)|uniprotkb:Regulatory protein TSC-22(gene name synonym)|uniprotkb:TGFB-stimulated clone 22 homolog(gene name synonym)|uniprotkb:Cerebral protein 2(gene name synonym)|uniprotkb:hucep-2(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867615|imex:IM-17207-122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230728.1|ensembl:ENSG00000102804(gene)|ensembl:ENST00000458659(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000580(TSC-22 / Dip / Bun)|mint:Q15714|refseq:NP_006013.1|refseq:NP_904358.2|entrezgene/locuslink:8848(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:8Q9EYhckfEz/DbkwrOUo0SMa1zo9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:308430145896B328|rigid:Yz2Ot9p6+IBSwuhcVaxr8fSvnL0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IXH7	uniprotkb:O00555	intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867605|imex:IM-17207-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N|entrezgene/locuslink:51497(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:1FD51283196944EF|rigid:Ep6EjrOe8/DcSN5NoaqMS92Adcs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92804	uniprotkb:O00555	intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867591|imex:IM-17207-120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:8148(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:0D22A2A289EAA1A2|rigid:ciOS8ZjAyhVAFWJ6WX0grTXGAkU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NBJ7	uniprotkb:O00555	intact:EBI-723091|uniprotkb:Q14DW5|uniprotkb:Q53ZE3|uniprotkb:Q96BH2|uniprotkb:Q9BRN3|uniprotkb:Q9BWI1|uniprotkb:Q9Y405|ensembl:ENSP00000400922|uniprotkb:B4DU41|uniprotkb:B4DWQ0	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:sumf2_human(display_long)|uniprotkb:SUMF2(gene name)|psi-mi:SUMF2(display_short)|uniprotkb:Sulfatase-modifying factor 2(gene name synonym)|uniprotkb:PSEC0171(orf name)|uniprotkb:UNQ1968/PRO4500(orf name)|uniprotkb:Paralog of formylglycine-generating enzyme(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867581|imex:IM-17207-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035934.2|refseq:NP_001035935.2|refseq:NP_001139805.1|refseq:NP_056226.2|refseq:NP_001123541.1|ensembl:ENSG00000129103(gene)|ensembl:ENST00000434526(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005532(Sulphate-modifying factor-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR042095|rcsb pdb:1Y4J|reactome:R-HSA-1660662|reactome:R-HSA-1663150|entrezgene/locuslink:25870(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:l5K3nL4Cf/sygAOzoS2fcH4rmL09606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:E4D47D600969AEF1|rigid:tj9aiPd6SXSXswBvrKkrZ1Jlmyo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43609	uniprotkb:O00555	intact:EBI-3866665|uniprotkb:Q6PNE0|uniprotkb:D3DNX6|ensembl:ENSP00000343785|ensembl:ENSP00000377871|ensembl:ENSP00000480540|ensembl:ENSP00000481675|ensembl:ENSP00000498292	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:spy1_human(display_long)|uniprotkb:SPRY1(gene name)|psi-mi:SPRY1(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867571|imex:IM-17207-118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005832.1|refseq:NP_955359.1|refseq:NP_001244967.1|refseq:NP_001244968.1|refseq:XP_005262743.1|ensembl:ENSG00000164056(gene)|ensembl:ENST00000339241(transcript)|ensembl:ENST00000394339(transcript)|ensembl:ENST00000610581(transcript)|ensembl:ENST00000622283(transcript)|ensembl:ENST00000651917(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001759"(organ induction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR007875(Sprouty)|interpro:IPR030783|mint:O43609|reactome:R-HSA-182971|refseq:XP_016863124.1|entrezgene/locuslink:10252(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:tbucIEQYibDQbBC1xVIZVDH2nIY9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:08EC5E80FCB7DF29|rigid:5CBjlEWR8s3BkYORRlH/yKm3lfg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07955	uniprotkb:O00555	intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867548|imex:IM-17207-116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A|entrezgene/locuslink:6426(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:8ED92F841F31E347|rigid:2nPypor7SNZmOcar3gFv96wiMW0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q9UHX1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867561|imex:IM-17207-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N|entrezgene/locuslink:22827(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:nL6ALA543VdThkempiJTWAOhoNA9606	intact-crc:603B198F58EC7B78|rigid:Eq4Gh0wK2YAjpXqedEm6UdMY68c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q96G27	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3867685|uniprotkb:B2RE02|uniprotkb:O95637|ensembl:ENSP00000233615	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:wbp1_human(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867691|imex:IM-17207-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_036609.1|ensembl:ENSP00000233615|ensembl:ENSG00000239779(gene)|ensembl:ENST00000233615(transcript)|go:"GO:0050699"(WW domain binding)|interpro:IPR021684|rcsb pdb:1JMQ|rcsb pdb:1K5R|entrezgene/locuslink:23559(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:TsFm/5qWoE81rmjKP9D/F5xZjww9606	intact-crc:3CB3FF3289C0A17B|rigid:9nZMUZHzlLgwSL7X6a1ejOV55JI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P04275	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867675|imex:IM-17207-128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_000543.2|ensembl:ENSG00000110799(gene)|ensembl:ENST00000261405(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0009611"(response to wounding)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0030168"(platelet activation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033093"(Weibel-Palade body)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051087"(chaperone binding)|dip:DIP-29667N|reactome:R-HSA-9672391|reactome:R-HSA-9672393|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7KWO|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|rcsb pdb:4NT5|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:1902533"(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|go:"GO:0070062"(extracellular exosome)|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|entrezgene/locuslink:7450(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:65BCEF43EC1F99E8|rigid:1x11WN0tkuElHSNndwvX2AjFKbQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N1B4	uniprotkb:O00555	intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867665|imex:IM-17207-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N|entrezgene/locuslink:6293(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:C501DBB009F328AF|rigid:jkAOhpCZIhax9cDUQnFfyKpSRFI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P26640	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-355765|uniprotkb:Q5JQ90|uniprotkb:Q96E77|uniprotkb:Q9UQM2|uniprotkb:B4DZ61|uniprotkb:B0V1N1|ensembl:ENSP00000211402|ensembl:ENSP00000364815|ensembl:ENSP00000401121|ensembl:ENSP00000403359|ensembl:ENSP00000415316	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:syvc_human(display_long)|uniprotkb:VARS1(gene name)|psi-mi:VARS1(display_short)|uniprotkb:G7A(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:VARS(gene name synonym)|uniprotkb:VARS2(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867655|imex:IM-17207-126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_006286.1|ensembl:ENSG00000096171(gene)|ensembl:ENSG00000204394(gene)|ensembl:ENSG00000224264(gene)|ensembl:ENSG00000226589(gene)|ensembl:ENSG00000231116(gene)|ensembl:ENST00000211402(transcript)|ensembl:ENST00000375663(transcript)|ensembl:ENST00000422694(transcript)|ensembl:ENST00000435657(transcript)|ensembl:ENST00000457796(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:P26640|reactome:R-HSA-379716|entrezgene/locuslink:7407(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:aPfpK0/C2KpCsMOI0sjCreufI509606	intact-crc:CD473D828CD46CA6|rigid:Z7E3TM3qLF505maTMAXptYAk/jU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P22695	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867645|imex:IM-17207-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|entrezgene/locuslink:7385(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	intact-crc:EB30CD804D7D129F|rigid:1hvSzo5Tt6gFja3kKEB6TKQAx6g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q9BVA1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867635|imex:IM-17207-124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)|entrezgene/locuslink:347733(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	intact-crc:9B3524A748E8C0BD|rigid:OwOqm9Zp1Oio4xCczUKVpLRF/nM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P41732	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-1042779|uniprotkb:Q8WVG5|uniprotkb:Q9UEY9|intact:EBI-1058752|uniprotkb:B2R5W7|uniprotkb:D3DWB1|ensembl:ENSP00000367743	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:tsn7_human(display_long)|uniprotkb:TSPAN7(gene name)|psi-mi:TSPAN7(display_short)|uniprotkb:A15(gene name synonym)|uniprotkb:DXS1692E(gene name synonym)|uniprotkb:MXS1(gene name synonym)|uniprotkb:TM4SF2(gene name synonym)|uniprotkb:Transmembrane 4 superfamily member 2(gene name synonym)|uniprotkb:Cell surface glycoprotein A15(gene name synonym)|uniprotkb:T-cell acute lymphoblastic leukemia-associated antigen 1(gene name synonym)|uniprotkb:Membrane component chromosome X surface marker 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867625|imex:IM-17207-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_004606.2|ensembl:ENSG00000156298(gene)|ensembl:ENST00000378482(transcript)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P41732|reactome:R-HSA-202733|reactome:R-HSA-416993|entrezgene/locuslink:7102(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:v5A8+QDjglRSkMJF7ypGSnJ0lAU9606	intact-crc:16BA2D319F9B1166|rigid:iH/nDw4EGe3t/Wz4aEvYivzNIKE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:Q9NP64	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867711|imex:IM-17207-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO|entrezgene/locuslink:51538(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:e71wAulRWX6cM59s3g8R42PWXeU9606	intact-crc:2561370009585FB5|rigid:GJ5am+9SacaMnUP0aj0hjBzu0sI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A6NK53	uniprotkb:O00555	intact:EBI-2689072|uniprotkb:B2RN78|uniprotkb:B2RN79|uniprotkb:Q86WL8|ensembl:ENSP00000375820|ensembl:ENSP00000507588	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:zn233_human(display_long)|uniprotkb:ZNF233(gene name)|psi-mi:ZNF233(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867721|imex:IM-17207-132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193934.1|refseq:NP_861421.2|ensembl:ENSG00000159915(gene)|ensembl:ENST00000391958(transcript)|ensembl:ENST00000683810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:353355(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:NaxB47UVUZPjAoBgDr9pvW91c2w9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:DA1EC606A2EECCF0|rigid:cr+c76rpmEWTbdSNRt3ULWpX66c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00555	uniprotkb:P49750	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-712871|ensembl:ENSP00000324463|uniprotkb:P49752|uniprotkb:Q96I64|uniprotkb:Q9P1V7	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:ylpm1_human(display_long)|uniprotkb:Nuclear protein ZAP3(gene name synonym)|uniprotkb:ZAP113(gene name synonym)|uniprotkb:YLPM1(gene name)|psi-mi:YLPM1(display_short)|uniprotkb:C14orf170(gene name synonym)|uniprotkb:ZAP3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867701|imex:IM-17207-130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	ensembl:ENSG00000119596(gene)|ensembl:ENST00000325680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0032204"(regulation of telomere maintenance)|interpro:IPR026314|interpro:IPR027417|refseq:NP_062535.2|ensembl:ENSP00000324463|dip:DIP-53676N|entrezgene/locuslink:56252(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:3w+7odPC5D2UQYimwmCgTBbvWR49606	intact-crc:0FD98D341F741BCF|rigid:9oHloCIYWLEAcVStH3VqzInCcfU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15265	intact:EBI-3867745	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	entrezgene/locuslink:728501	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:loc728501(display_short)|psi-mi:EBI-3867745(display_long)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867742|imex:IM-17207-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2	entrezgene/locuslink:728501(identity)	-	-	no-uniprot-update:|caution:LOC728501/Entrez Gene entry =728501/  RPL21P75 ribosomal protein L21 pseudogene 75  does not have any protein listed.	caution:LOC728501/Gene ID 728501/ RPL21P75 ribosomal protein L21 pseudogene 75  refers to pseudogene locus without any protein listed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	-	intact-crc:BE4B9AB0D36DA8F3	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A6NEM1	uniprotkb:O00555	intact:EBI-5916454|uniprotkb:H0YK89|uniprotkb:A0A087WXJ1|uniprotkb:A6NFL8|uniprotkb:Q8IVV3|ensembl:ENSP00000479589|ensembl:ENSP00000481078	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:gg6l9_human(display_long)|uniprotkb:GOLGA6L9(gene name)|psi-mi:GOLGA6L9(display_short)|uniprotkb:GOLGA6L20(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3867748|imex:IM-17207-134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278349.1|refseq:NP_937824.3|ensembl:ENSG00000197978(gene)|ensembl:ENSG00000274320(gene)|ensembl:ENST00000618348(transcript)|ensembl:ENST00000620574(transcript)|interpro:IPR026737|interpro:IPR043976	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)	-	-	-	caution:"The protein flj40113  (Gene ID 374650), refers to a pseudogene locus, The associated RefSeq protein  was \"permanently suppressed because it is now thought that this gene is a pseudogene or a nonsense-mediated mRNA decay (NMD) candidate.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/04/04	2018/09/18	rogid:Bp4OxQiwnX2f36yPdNr2uBKvkwE9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:CA7CCEF5D45EC2F8|rigid:MvNrUF+/kSZXT8I1BVU5Pp8JQ/8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00468	uniprotkb:O15265	intact:EBI-947482|uniprotkb:Q5SVA2|uniprotkb:Q60FE1|uniprotkb:Q7KYS8|uniprotkb:Q8N4J5|uniprotkb:Q96IC1|uniprotkb:Q9BTD4|uniprotkb:Q5SVA1	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:agrin_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868142|imex:IM-17207-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940978.2|interpro:IPR004850(Agrin NtA)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:XP_005244806.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003884(Factor I membrane attack complex)|mint:O00468|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050808"(synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-419037|reactome:R-HSA-4420332|reactome:R-HSA-975634|interpro:IPR036058|interpro:IPR036364|refseq:NP_001292204.1|entrezgene/locuslink:375790(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:LRk4v4aYLk5kep9EIbjjiCGM7OM9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:9B378A86429CA5F4|rigid:M1f2bTgN+ZOz9mwB2jNrvUZcOGw	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9P209	uniprotkb:O15265	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868157|imex:IM-17207-136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|isoform-comment:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:F23683594F889385|rigid:FUC6dg7Isc+szkyiWS7YpQgWCkE	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O15265	uniprotkb:Q7Z7M0	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-947617|uniprotkb:O75097|uniprotkb:A8KAY0|ensembl:ENSP00000251268	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:megf8_human(display_long)|uniprotkb:MEGF8(gene name)|psi-mi:MEGF8(display_short)|uniprotkb:EGFL4(gene name synonym)|uniprotkb:KIAA0817(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 4(gene name synonym)|uniprotkb:C19orf49(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868232|imex:IM-17207-141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001401.2|refseq:NP_001258867.1|ensembl:ENSG00000105429(gene)|ensembl:ENST00000251268(transcript)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0055113"(epiboly involved in gastrulation with mouth forming second)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0097155"(fasciculation of sensory neuron axon)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016201(Plexin-like fold)|interpro:IPR018097|interpro:IPR024731|interpro:IPR035914|mint:Q7Z7M0|go:"GO:0048704"(embryonic skeletal system morphogenesis)|entrezgene/locuslink:1954(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:NaA9e3P2Wh8y5vrZQQPOYHh8ogc9606	intact-crc:9FC09930960E800E|rigid:n1WT+CJY1w7HM8P1rrBxUsgfp48	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O15265	uniprotkb:P07942	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868172|imex:IM-17207-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2|entrezgene/locuslink:3912(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606	intact-crc:D5D1D9375994585A|rigid:cdmyPduPFDMLGb6/8jv2s+uOUZU	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O15265	uniprotkb:Q8N2S1	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868187|imex:IM-17207-138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379|entrezgene/locuslink:8425(identity)	-	-	-	figure legend:Table S2|isoform-comment:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:41DF06578D09E8F3|rigid:rwEloRkhKx6IIl/6wkkzK5P10i0	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75095	uniprotkb:O15265	intact:EBI-947597|uniprotkb:Q5VV39|uniprotkb:Q4AC86|ensembl:ENSP00000348982	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:megf6_human(display_long)|uniprotkb:MEGF6(gene name)|psi-mi:MEGF6(display_short)|uniprotkb:EGFL3(gene name synonym)|uniprotkb:KIAA0815(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 3(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868217|imex:IM-17207-140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001400.3|ensembl:ENSG00000162591(gene)|ensembl:ENST00000356575(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|mint:O75095|entrezgene/locuslink:1953(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|isoform-comment:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:/4HcLiv4UEW2qmvoV2OTj110y1I9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:B9AC96AD98C6E7CF|rigid:CvFnXCQjZ9+XQ4pcs6gUBOuquhs	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O15265	uniprotkb:O00339	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-949020|uniprotkb:A8K106|uniprotkb:E7EW74|uniprotkb:E9PD48|uniprotkb:E9PGL2|ensembl:ENSP00000254898|ensembl:ENSP00000430487|uniprotkb:Q6UWA5|uniprotkb:Q7Z5X1|uniprotkb:Q8NDE6|uniprotkb:Q96FT5|uniprotkb:Q9NSZ1	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:matn2_human(display_long)|uniprotkb:MATN2(gene name)|psi-mi:MATN2(display_short)|uniprotkb:UNQ193/PRO219(orf name)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868202|imex:IM-17207-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	dip:DIP-47267N|ensembl:ENSG00000132561(gene)|ensembl:ENST00000254898(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0031012"(extracellular matrix)|ensembl:ENST00000520016(transcript)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019466|interpro:IPR026823|interpro:IPR030747|interpro:IPR036337|interpro:IPR036465|refseq:NP_002371.3|refseq:NP_085072.2|refseq:NP_001304677.1|entrezgene/locuslink:4147(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:umvJixncdhOkQvywPNFjPo1Aqx89606	intact-crc:8BDEEB3136F12C8D|rigid:o3DW48Lf/sYuodupRbjRAfaB2rY	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IZP0	uniprotkb:O00555	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868292|imex:IM-17207-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N|entrezgene/locuslink:10006(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:D61872D0DA20A230|rigid:hfCZYfAWtoSo6VybZys3CY4ZvEk	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y3T9	uniprotkb:O15265	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868247|imex:IM-17207-142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756|entrezgene/locuslink:26155(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|isoform-comment:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:E671EE778F3DA399|rigid:OIShM1q1Ni5Y2dTLxO0fUSui/z8	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O15265	uniprotkb:Q8IUQ4	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	intact:EBI-747107|uniprotkb:O43269|uniprotkb:Q49A58|uniprotkb:A0FKF3|uniprotkb:Q92880|ensembl:ENSP00000369343|ensembl:ENSP00000378214|ensembl:ENSP00000456421	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:siah1_human(display_long)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868277|imex:IM-17207-144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	refseq:XP_006721309.1|refseq:NP_001006611.1|refseq:NP_003022.3|refseq:XP_011521581.1|ensembl:ENST00000380006(transcript)|ensembl:ENST00000394725(transcript)|ensembl:ENST00000568007(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|mint:Q8IUQ4|rcsb pdb:2A25|rcsb pdb:4C9Z|rcsb pdb:4CA1|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D|rcsb pdb:4X3G|rcsb pdb:5WZZ|reactome:R-HSA-373752|reactome:R-HSA-977225|reactome:R-HSA-983168|ensembl:ENSG00000196470(gene)|dip:DIP-35684N|entrezgene/locuslink:6477(identity)	-	-	-	figure legend:Table S2|isoform-comment:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	rogid:O6+z1g9K1ij87Xgo5/Ykl5Q3vUQ9606	intact-crc:C7ABB9C0D096A13B|rigid:4DCFzlIryS0T/CKepKSOHENwYQ4	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:O00468	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-947482|uniprotkb:Q5SVA2|uniprotkb:Q60FE1|uniprotkb:Q7KYS8|uniprotkb:Q8N4J5|uniprotkb:Q96IC1|uniprotkb:Q9BTD4|uniprotkb:Q5SVA1	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:agrin_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868307|imex:IM-17207-146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_940978.2|interpro:IPR004850(Agrin NtA)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:XP_005244806.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003884(Factor I membrane attack complex)|mint:O00468|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050808"(synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-419037|reactome:R-HSA-4420332|reactome:R-HSA-975634|interpro:IPR036058|interpro:IPR036364|refseq:NP_001292204.1|entrezgene/locuslink:375790(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:LRk4v4aYLk5kep9EIbjjiCGM7OM9606	intact-crc:1AB2693D83CA699A|rigid:m2indz5EWVyObq0PGsdrkk08zjI	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P37198	uniprotkb:O15265	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868262|imex:IM-17207-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|entrezgene/locuslink:6314(identity)	-	-	-	figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2014/10/16	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606	intact-crc:7AA86117ED5DF346|rigid:cKjl5H9wUqlu45i9og6KbhknrL4	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P67870	uniprotkb:O00555	intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868382|imex:IM-17207-150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|entrezgene/locuslink:1460(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:26A4E3439D4986A0|rigid:sU1C7Dpe0oAOn7cAl1WtMRJFQ4E	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O95153	uniprotkb:O00555	intact:EBI-5915931|uniprotkb:O75111|uniprotkb:Q8N5W3|ensembl:ENSP00000345824|intact:EBI-28971165	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:rimb1_human(display_long)|uniprotkb:TSPOAP1(gene name)|psi-mi:TSPOAP1(display_short)|uniprotkb:BZRAP1(gene name synonym)|uniprotkb:KIAA0612(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-interacting protein(gene name synonym)|uniprotkb:RBP1(gene name synonym)|uniprotkb:RIMBP1(gene name synonym)|uniprotkb:RIMS-binding protein 1(gene name synonym)|uniprotkb:TSPO-associated protein 1(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868367|imex:IM-17207-149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000268893|ensembl:ENSP00000268893|ensembl:ENSP00000345824|refseq:XP_006722236.1|refseq:NP_001248764.1|refseq:NP_004749.2|refseq:NP_077729.1|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|mint:O95153|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-196108|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000005379(gene)|ensembl:ENST00000343736(transcript)|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:9256(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:nOwDlLr5DTjN2tJNR3h0zxrU1Z49606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:E8D055B4D4BB16A2|rigid:IE7L9YftVGWJI3/EztgnuqBOr8s	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z5H3	uniprotkb:O00555	intact:EBI-3866859|uniprotkb:A0AVP7|uniprotkb:A5YM75|uniprotkb:Q6ZSB0|uniprotkb:B9EGA0|uniprotkb:O00152|uniprotkb:B4DED8|uniprotkb:C9JDM2|ensembl:ENSP00000249601	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:rhg22_human(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868352|imex:IM-17207-148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334667.1|refseq:XP_011538306.1|refseq:NP_067049.2|refseq:NP_001242953.1|refseq:NP_001242955.1|refseq:NP_001242954.1|ensembl:ENSP00000249601|ensembl:ENST00000417247|ensembl:ENSP00000410054|ensembl:ENST00000417912|ensembl:ENSP00000412461|ensembl:ENST00000435790|ensembl:ENSP00000416701|ensembl:ENSG00000128805(gene)|ensembl:ENST00000249601(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|mint:Q7Z5H3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|entrezgene/locuslink:58504(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"\"Interaction observed in the presence of MPc isoform that splices to an immediate stop codon, resulting in a shorter cytoplasmic tail lacking the polyQ tract.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:B6GppfBTWo7eKA5XTxP6oOG56789606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:2CD82D50167B159C|rigid:jaq4RMtlaly/2+V+C+3xwO/6jsA	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q86SJ2	uniprotkb:O00555	intact:EBI-3866830|uniprotkb:Q96CN8|uniprotkb:Q4VBP6|uniprotkb:Q7Z4A0|ensembl:ENSP00000266581|ensembl:ENSP00000406020|ensembl:ENSP00000449034	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:amgo2_human(display_long)|uniprotkb:AMIGO2(gene name)|psi-mi:AMIGO2(display_short)|uniprotkb:ALI1(gene name synonym)|uniprotkb:AMIGO-2(gene name synonym)|uniprotkb:Alivin-1(gene name synonym)|uniprotkb:Differentially expressed in gastric adenocarcinomas(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868337|imex:IM-17207-147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137140.1|refseq:NP_862830.1|refseq:XP_005268894.1|ensembl:ENST00000266581(transcript)|ensembl:ENST00000429635(transcript)|ensembl:ENST00000550413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007420"(brain development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051965"(positive regulation of synapse assembly)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031283|interpro:IPR031286|interpro:IPR032675|interpro:IPR036179|reactome:R-HSA-9013149|reactome:R-HSA-9013423|ensembl:ENSG00000139211(gene)|entrezgene/locuslink:347902(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"\"Interaction observed in the presence of MPc isoform that splices to an immediate stop codon, resulting in a shorter cytoplasmic tail lacking the polyQ tract.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:c5JBCzA3CGbyFLbRePuJSNfZO/I9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:B33C7C57229D19B7|rigid:A3SSsZA9O2eGpUq0gDZLZZTfTp0	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:P28799	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868427|imex:IM-17207-152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N|entrezgene/locuslink:2896(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	intact-crc:A0C77E31113A81E3|rigid:vh5CCIiTl2bZ3owlULQY/X6O8Vc	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P15822	uniprotkb:O00555	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868457|imex:IM-17207-153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002105.3|ensembl:ENSG00000095951(gene)|ensembl:ENST00000379388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|entrezgene/locuslink:3096(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:rugwzqsTO0X8mJ5Zy3msTqc6dr09606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:F6E14CAC9CA19711|rigid:AOf+NxPtfioxIZon+IitJzpYQ0c	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:O75953	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-5655937|uniprotkb:J3KQM9|uniprotkb:Q8TDR7|uniprotkb:Q96EM4|uniprotkb:B3KN14|uniprotkb:Q5T656|uniprotkb:B4DSA6|uniprotkb:J3KR08|ensembl:ENSP00000312517|ensembl:ENSP00000441999|ensembl:ENSP00000506753	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:dnjb5_human(display_long)|uniprotkb:HSC40(gene name synonym)|uniprotkb:Heat shock protein Hsp40-2(gene name synonym)|uniprotkb:Heat shock protein Hsp40-3(gene name synonym)|uniprotkb:Heat shock protein cognate 40(gene name synonym)|uniprotkb:DNAJB5(gene name)|psi-mi:DNAJB5(display_short)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868412|imex:IM-17207-151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:XP_011516144.1|refseq:NP_001128476.2|refseq:NP_001128477.1|refseq:NP_036398.3|refseq:XP_005251485.1|refseq:XP_006716814.1|ensembl:ENSG00000137094(gene)|ensembl:ENST00000312316(transcript)|ensembl:ENST00000545841(transcript)|ensembl:ENST00000684748(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:O75953|entrezgene/locuslink:25822(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:tXimNOFcGTGvoThdisoSYm9koR89606	intact-crc:F3C01D37F93F5DCF|rigid:WXkfXfkVihVDyDbKXagBvdl2Fjg	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P07942	uniprotkb:O00555	intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868487|imex:IM-17207-154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:1C5A03223DEA844B|rigid:YvNNM1G6MsybeWmnCUPiw5BSxkk	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8N2S1	uniprotkb:O00555	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868532|imex:IM-17207-156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|ensembl:ENSG00000090006(gene)|ensembl:ENST00000308370(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006457"(protein folding)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|mint:Q8N2S1|reactome:R-HSA-2129379|entrezgene/locuslink:8425(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:549F9A3644B43079|rigid:jD0tWaUoAjkBjOfanegVptl/9Ww	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O94910	uniprotkb:O00555	intact:EBI-3389315|uniprotkb:Q9BU07|uniprotkb:Q9HAR3|uniprotkb:Q96IE7|ensembl:ENSP00000340688|ensembl:ENSP00000500240	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:agrl1_human(display_long)|uniprotkb:ADGRL1(gene name)|psi-mi:ADGRL1(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 1(gene name synonym)|uniprotkb:KIAA0821(gene name synonym)|uniprotkb:LEC2(gene name synonym)|uniprotkb:LPHN1(gene name synonym)|uniprotkb:Latrophilin-1(gene name synonym)|uniprotkb:Lectomedin-2(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868517|imex:IM-17207-155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008701.1|refseq:NP_055736.2|ensembl:ENSG00000072071(gene)|ensembl:ENSG00000288324(gene)|ensembl:ENST00000340736(transcript)|ensembl:ENST00000672190(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016524"(latrotoxin receptor activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090129"(positive regulation of synapse maturation)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR031234|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|mint:O94910|entrezgene/locuslink:22859(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:kHETaGfz/t0XytDX2HWU7/xty589606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:53B71E6589B0AFC6|rigid:tust5Bwpz5hC8O8kdskDgqPIOn4	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00339	uniprotkb:O00555	intact:EBI-949020|uniprotkb:A8K106|uniprotkb:E7EW74|uniprotkb:E9PD48|uniprotkb:E9PGL2|ensembl:ENSP00000254898|ensembl:ENSP00000430487|uniprotkb:Q6UWA5|uniprotkb:Q7Z5X1|uniprotkb:Q8NDE6|uniprotkb:Q96FT5|uniprotkb:Q9NSZ1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:matn2_human(display_long)|uniprotkb:MATN2(gene name)|psi-mi:MATN2(display_short)|uniprotkb:UNQ193/PRO219(orf name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868562|imex:IM-17207-157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-47267N|ensembl:ENSG00000132561(gene)|ensembl:ENST00000254898(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0031012"(extracellular matrix)|ensembl:ENST00000520016(transcript)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019466|interpro:IPR026823|interpro:IPR030747|interpro:IPR036337|interpro:IPR036465|refseq:NP_002371.3|refseq:NP_085072.2|refseq:NP_001304677.1|entrezgene/locuslink:4147(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"\"Interaction observed in the presence of MPc isoform that splices to an immediate stop codon, resulting in a shorter cytoplasmic tail lacking the polyQ tract.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:umvJixncdhOkQvywPNFjPo1Aqx89606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:845E0A10554FBA0E|rigid:Qb0NKX9bXmRAoEta4YUD6VlWkQA	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:O75095	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-947597|uniprotkb:Q5VV39|uniprotkb:Q4AC86|ensembl:ENSP00000348982	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:megf6_human(display_long)|uniprotkb:MEGF6(gene name)|psi-mi:MEGF6(display_short)|uniprotkb:EGFL3(gene name synonym)|uniprotkb:KIAA0815(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868577|imex:IM-17207-158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001400.3|ensembl:ENSG00000162591(gene)|ensembl:ENST00000356575(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|mint:O75095|entrezgene/locuslink:1953(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:/4HcLiv4UEW2qmvoV2OTj110y1I9606	intact-crc:7FD742B8484CEC8D|rigid:zzfkky90zXuVCRqznxwwxADv1ik	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z7M0	uniprotkb:O00555	intact:EBI-947617|uniprotkb:O75097|uniprotkb:A8KAY0|ensembl:ENSP00000251268	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:megf8_human(display_long)|uniprotkb:MEGF8(gene name)|psi-mi:MEGF8(display_short)|uniprotkb:EGFL4(gene name synonym)|uniprotkb:KIAA0817(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 4(gene name synonym)|uniprotkb:C19orf49(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868592|imex:IM-17207-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001401.2|refseq:NP_001258867.1|ensembl:ENSG00000105429(gene)|ensembl:ENST00000251268(transcript)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0055113"(epiboly involved in gastrulation with mouth forming second)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0097155"(fasciculation of sensory neuron axon)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016201(Plexin-like fold)|interpro:IPR018097|interpro:IPR024731|interpro:IPR035914|mint:Q7Z7M0|go:"GO:0048704"(embryonic skeletal system morphogenesis)|entrezgene/locuslink:1954(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:NaA9e3P2Wh8y5vrZQQPOYHh8ogc9606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:A1DBDB7A168653DA|rigid:4jxWuLtC4w4luq2vIZmPqOT3U/U	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:Q9BVA1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868652|imex:IM-17207-162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)|entrezgene/locuslink:347733(identity)	-	-	-	figure legend:Table S2|isoform-comment:"\"Interaction observed in the presence of MPc isoform that splices to an immediate stop codon, resulting in a shorter cytoplasmic tail lacking the polyQ tract.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	intact-crc:D15B4C32A3CF3C02|rigid:OwOqm9Zp1Oio4xCczUKVpLRF/nM	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:Q8IXT5	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-3044077|ensembl:ENSP00000382239|ensembl:ENSP00000427729|ensembl:ENSP00000428269|ensembl:ENSP00000429807|ensembl:ENSP00000430474|uniprotkb:A8MYB5	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:rb12b_human(display_long)|uniprotkb:RBM12B(gene name)|psi-mi:RBM12B(display_short)|uniprotkb:RNA-binding motif protein 12B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868622|imex:IM-17207-160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:XP_016868895.1|refseq:XP_016868896.1|refseq:XP_016868897.1|ensembl:ENSG00000183808(gene)|ensembl:ENST00000399300(transcript)|ensembl:ENST00000517700(transcript)|ensembl:ENST00000518597(transcript)|ensembl:ENST00000519109(transcript)|ensembl:ENST00000520560(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034588|interpro:IPR034858|interpro:IPR035979|refseq:XP_011515329.1|refseq:XP_011515330.1|refseq:XP_011515331.1|refseq:NP_976324.2|refseq:XP_005250972.1|entrezgene/locuslink:389677(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:WFJYO2tbSpgVmVVnSyFLn4O2+HM9606	intact-crc:5B85F2E5AD4B1372|rigid:Cr01/5x2xWGuBErgwmmVHPJBt+I	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00555	uniprotkb:Q9UHX1	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868637|imex:IM-17207-161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N|entrezgene/locuslink:22827(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	rogid:nL6ALA543VdThkempiJTWAOhoNA9606	intact-crc:AA16BC313B01A59C|rigid:Eq4Gh0wK2YAjpXqedEm6UdMY68c	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P22695	uniprotkb:O00555	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868667|imex:IM-17207-163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|entrezgene/locuslink:7385(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:B91903CA9D168542|rigid:1hvSzo5Tt6gFja3kKEB6TKQAx6g	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P49750	uniprotkb:O00555	intact:EBI-712871|ensembl:ENSP00000324463|uniprotkb:P49752|uniprotkb:Q96I64|uniprotkb:Q9P1V7	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658|ensembl:ENSP00000353362	psi-mi:ylpm1_human(display_long)|uniprotkb:Nuclear protein ZAP3(gene name synonym)|uniprotkb:ZAP113(gene name synonym)|uniprotkb:YLPM1(gene name)|psi-mi:YLPM1(display_short)|uniprotkb:C14orf170(gene name synonym)|uniprotkb:ZAP3(gene name synonym)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kahle et al. (2011)	pubmed:21078624|imex:IM-17207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3868682|imex:IM-17207-164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119596(gene)|ensembl:ENST00000325680(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0032204"(regulation of telomere maintenance)|interpro:IPR026314|interpro:IPR027417|refseq:NP_062535.2|ensembl:ENSP00000324463|dip:DIP-53676N|entrezgene/locuslink:56252(identity)	refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_000059.3|refseq:NP_075461.2|ensembl:ENSP00000353362|ensembl:ENST00000637276|ensembl:ENSP00000489777|ensembl:ENST00000637432|ensembl:ENSP00000490617|ensembl:ENST00000638009|ensembl:ENSP00000489913|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|go:"GO:0008219"(cell death)|interpro:IPR031649|rcsb pdb:3BXK|reactome:R-HSA-422356|reactome:R-HSA-112308|ensembl:ENSG00000141837(gene)|ensembl:ENST00000360228(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|entrezgene/locuslink:773(identity)	-	-	-	figure legend:Table S2|isoform-comment:"Interaction observed in the presence of MPI isoform that includes exon 47 and the CAG coding repeat that translates into a polyglutamine (polyQ) tract in the cytoplasmic  tail of the protein."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/04/04	2018/09/18	rogid:3w+7odPC5D2UQYimwmCgTBbvWR49606	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:84CF5CA24E4DD6D9|rigid:9oHloCIYWLEAcVStH3VqzInCcfU	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)