#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q69027 uniprotkb:Q8C165 intact:EBI-3650820 intact:EBI-3862825|uniprotkb:Q3UNX0|uniprotkb:Q8R117|ensembl:ENSMUSP00000046079|ensembl:ENSMUSP00000108012 psi-mi:x_hbvcj(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym) psi-mi:p20d1_mouse(display_long)|uniprotkb:Pm20d1(gene name)|psi-mi:Pm20d1(display_short)|uniprotkb:Peptidase M20 domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kumar et al. (2011) pubmed:21068253|imex:IM-16964 taxid:928302(hbvcj)|taxid:928302(Hepatitis B virus genotype C subtype ayr) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3650891|imex:IM-16964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60873N|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X) refseq:NP_835180.2|refseq:XP_006529401.1|ensembl:ENSMUSG00000042251(gene)|ensembl:ENSMUST00000048660(transcript)|ensembl:ENSMUST00000112393(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0016829"(lyase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0043604"(amide biosynthetic process)|go:"GO:0043605"(cellular amide catabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000275"(regulation of oxidative phosphorylation uncoupler activity)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR036264|mint:Q8C165|reactome:R-MMU-9673163|go:"GO:0006520"(cellular amino acid metabolic process) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2011/03/04 2014/10/16 rogid:ovpKFR8QUWqElYM48c6ZP7wl8og928302 rogid:DoaT6RAftM22KLFf53RVIOiexDw10090 intact-crc:19490682BDEB9C36|rigid:GumvcNkLXkhU8tjP8MT0l9WEOQU false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q69027 uniprotkb:A2AS03 intact:EBI-3650820 intact:EBI-3862834|ensembl:ENSMUSP00000091756 psi-mi:x_hbvcj(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym) psi-mi:a2as03_mouse(display_long)|uniprotkb:Helz2(gene name)|psi-mi:Helz2(display_short)|uniprotkb:BC006779(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kumar et al. (2011) pubmed:21068253|imex:IM-16964 taxid:928302(hbvcj)|taxid:928302(Hepatitis B virus genotype C subtype ayr) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3650891|imex:IM-16964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60873N|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X) refseq:XP_006500664.1|ensembl:ENSMUSG00000027580(gene)|ensembl:ENSMUST00000094203(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031191|interpro:IPR036236|interpro:IPR041677|interpro:IPR041679 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2011/03/04 2014/10/16 rogid:ovpKFR8QUWqElYM48c6ZP7wl8og928302 rogid:C7tSkdUWLqjECQFFzbnoqSs5GVc10090 intact-crc:19490682BDEB9C36|rigid:GumvcNkLXkhU8tjP8MT0l9WEOQU false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q69027 uniprotkb:Q8VCF0 intact:EBI-3650820 intact:EBI-3862816|ensembl:ENSMUSP00000038339|ensembl:ENSMUSP00000105828 psi-mi:x_hbvcj(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym) psi-mi:mavs_mouse(display_long)|uniprotkb:Mavs(gene name)|psi-mi:Mavs(display_short)|uniprotkb:Ips1(gene name synonym)|uniprotkb:Visa(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kumar et al. (2011) pubmed:21068253|imex:IM-16964 taxid:928302(hbvcj)|taxid:928302(Hepatitis B virus genotype C subtype ayr) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3650891|imex:IM-16964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60873N|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X) refseq:NP_001193314.1|refseq:NP_659137.1|dip:DIP-43890N|ensembl:ENSMUSG00000037523(gene)|ensembl:ENSMUST00000041362(transcript)|ensembl:ENSMUST00000110199(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q8VCF0|rcsb pdb:4GHU|reactome:R-MMU-168928|reactome:R-MMU-936440 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2011/03/04 2014/10/16 rogid:ovpKFR8QUWqElYM48c6ZP7wl8og928302 rogid:ffvMw8iY9tllLKmqNE+WCP0Bk/E10090 intact-crc:19490682BDEB9C36|rigid:GumvcNkLXkhU8tjP8MT0l9WEOQU false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q69027 uniprotkb:G5E8K5 intact:EBI-3650820 intact:EBI-457262|uniprotkb:G5E8K4|uniprotkb:Q3TSJ8|uniprotkb:Q4U205|uniprotkb:Q4U206|uniprotkb:Q4U256|uniprotkb:Q4U260|uniprotkb:Q61307|uniprotkb:Q8CBN3|uniprotkb:Q8VC68|uniprotkb:O08866|uniprotkb:O08867|uniprotkb:Q61305|uniprotkb:Q61306|uniprotkb:Q61308|uniprotkb:Q61309|uniprotkb:Q61310|intact:EBI-2133089|ensembl:ENSMUSP00000090090|ensembl:ENSMUSP00000138326 psi-mi:x_hbvcj(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym) psi-mi:ank3_mouse(display_long)|uniprotkb:Ankyrin-G(gene name synonym)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kumar et al. (2011) pubmed:21068253|imex:IM-16964 taxid:928302(hbvcj)|taxid:928302(Hepatitis B virus genotype C subtype ayr) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3650891|imex:IM-16964-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60873N|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X) refseq:NP_666117.2|refseq:XP_006513202.1|refseq:NP_033800.2|refseq:NP_733788.2|refseq:NP_733789.1|refseq:NP_733790.2|refseq:NP_733791.2|refseq:NP_733924.2|refseq:NP_733925.2|refseq:NP_733926.2|ensembl:ENSMUSG00000069601(gene)|ensembl:ENSMUST00000092434(transcript)|ensembl:ENSMUST00000182884(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010650"(positive regulation of cell communication by electrical coupling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014704"(intercalated disc)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043194"(axon initial segment)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0050808"(synapse organization)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0099612"(protein localization to axon)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1900827"(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|mint:G5E8K5 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2011/03/04 2014/10/16 rogid:ovpKFR8QUWqElYM48c6ZP7wl8og928302 rogid:sPFqnXYHQKlR6xjYE/VqOvNFxG010090 intact-crc:19490682BDEB9C36|rigid:GumvcNkLXkhU8tjP8MT0l9WEOQU false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z434 uniprotkb:Q69027 intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34 intact:EBI-3650820 psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym) psi-mi:x_hbvcj(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kumar et al. (2011) pubmed:21068253|imex:IM-16964 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:928302(hbvcj)|taxid:928302(Hepatitis B virus genotype C subtype ayr) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3650929|imex:IM-16964-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N dip:DIP-60873N|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X) - - - figure legend:Fig. 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2011/03/04 2014/10/16 rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606 rogid:ovpKFR8QUWqElYM48c6ZP7wl8og928302 intact-crc:55F06BCE80C90445|rigid:UE4vJZ7W3DkqoOXCAAecNRxtKhI false ha tag:?-?|flag tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q69027 uniprotkb:Q7Z434 intact:EBI-3650820 intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34 psi-mi:x_hbvcj(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym) psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kumar et al. (2011) pubmed:21068253|imex:IM-16964 taxid:928302(hbvcj)|taxid:928302(Hepatitis B virus genotype C subtype ayr) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3650933|imex:IM-16964-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60873N|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X) refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N - - - figure legend:Fig. 2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2011/03/04 2014/10/16 rogid:ovpKFR8QUWqElYM48c6ZP7wl8og928302 rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606 intact-crc:4825CD5B4B55A998|rigid:UE4vJZ7W3DkqoOXCAAecNRxtKhI false - ha tag:c-c|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)