#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q00560	uniprotkb:P22272	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-3862989|ensembl:ENSMUSP00000029559	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:il6ra_mouse(display_long)|uniprotkb:Il6ra(gene name)|psi-mi:Il6ra(display_short)|uniprotkb:Il6r(gene name synonym)|uniprotkb:IL-6R 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Stumhofer et al. (2010)	pubmed:21057510|imex:IM-17010	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862995|imex:IM-17010-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	refseq:NP_034689.2|ensembl:ENSMUSG00000027947(gene)|ensembl:ENSMUST00000029559(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004921"(interleukin-11 receptor activity)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010536"(positive regulation of activation of Janus kinase activity)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019970"(interleukin-11 binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034097"(response to cytokine)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048589"(developmental growth)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070119"(ciliary neurotrophic factor binding)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|interpro:IPR003530(Long hematopoietin receptor, soluble alpha chain, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:7.27x10^7(parameter unit)|koff:1.38x10^-8(molar)	2011/03/24	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:pXUycQrab3Zm8S8wnohZ/q+DvpY10090	intact-crc:F6495912922FA5D8|rigid:esQ77VuOGwRi+5JXpkdvsBXIiZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00560	uniprotkb:P08505	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-3862996|uniprotkb:Q3UCQ0|uniprotkb:Q8BN26|ensembl:ENSMUSP00000026845	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:il6_mouse(display_long)|uniprotkb:Il6(gene name)|psi-mi:Il6(display_short)|uniprotkb:Il-6(gene name synonym)|uniprotkb:B-cell hybridoma growth factor(gene name synonym)|uniprotkb:Interleukin HP-1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Stumhofer et al. (2010)	pubmed:21057510|imex:IM-17010	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862995|imex:IM-17010-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	refseq:NP_112445.1|refseq:NP_001300983.1|ensembl:ENSMUSG00000025746(gene)|ensembl:ENSMUST00000026845(transcript)|go:"GO:0001781"(neutrophil apoptotic process)|go:"GO:0001878"(response to yeast)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0002384"(hepatic immune response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0014823"(response to activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031000"(response to caffeine)|go:"GO:0031175"(neuron projection development)|go:"GO:0031294"(lymphocyte costimulation)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046849"(bone remodeling)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048635"(negative regulation of muscle organ development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0097421"(liver regeneration)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990646"(cellular response to prolactin)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000660"(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003574(Interleukin-6)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR030473|interpro:IPR030474|rcsb pdb:2L3Y|go:"GO:0051607"(defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|reactome:R-MMU-1059683|go:"GO:0060252"(positive regulation of glial cell proliferation)|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-381426|reactome:R-MMU-8957275|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060664"(epithelial cell proliferation involved in salivary gland morphogenesis)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0070091"(glucagon secretion)|go:"GO:0070092"(regulation of glucagon secretion)	-	-	-	figure legend:Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:7.27x10^7(parameter unit)|koff:1.38x10^-8(molar)	2011/03/24	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:QipydNlQPlQv8mneHmNraOpI33Y10090	intact-crc:F6495912922FA5D8|rigid:esQ77VuOGwRi+5JXpkdvsBXIiZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00560	uniprotkb:Q8K3I6	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-3863005|ensembl:ENSMUSP00000054637	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:il27a_mouse(display_long)|uniprotkb:Il27(gene name)|psi-mi:Il27(display_short)|uniprotkb:Il27a(gene name synonym)|uniprotkb:p28(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Stumhofer et al. (2010)	pubmed:21057510|imex:IM-17010	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863008|imex:IM-17010-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	refseq:NP_663611.1|ensembl:ENSMUST00000058429(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045523"(interleukin-27 receptor binding)|go:"GO:0045625"(regulation of T-helper 1 cell differentiation)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR026207|reactome:R-MMU-9020956|ensembl:ENSMUSG00000044701(gene)	-	-	-	figure legend:Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:3.35x10^7(parameter unit)|koff:2.98x10^-8(molar)	2011/03/24	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:e12TIBOkx+KRGoI0tVhFzfInB7410090	intact-crc:126FAEA47BDC6039|rigid:x9Dbz1ET8gW+K6rm0cCWF7PkyEQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00560	uniprotkb:P08505	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-3862996|uniprotkb:Q3UCQ0|uniprotkb:Q8BN26|ensembl:ENSMUSP00000026845	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:il6_mouse(display_long)|uniprotkb:Il6(gene name)|psi-mi:Il6(display_short)|uniprotkb:Il-6(gene name synonym)|uniprotkb:B-cell hybridoma growth factor(gene name synonym)|uniprotkb:Interleukin HP-1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Stumhofer et al. (2010)	pubmed:21057510|imex:IM-17010	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863008|imex:IM-17010-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	refseq:NP_112445.1|refseq:NP_001300983.1|ensembl:ENSMUSG00000025746(gene)|ensembl:ENSMUST00000026845(transcript)|go:"GO:0001781"(neutrophil apoptotic process)|go:"GO:0001878"(response to yeast)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0002384"(hepatic immune response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0014823"(response to activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031000"(response to caffeine)|go:"GO:0031175"(neuron projection development)|go:"GO:0031294"(lymphocyte costimulation)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046849"(bone remodeling)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048635"(negative regulation of muscle organ development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0097421"(liver regeneration)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990646"(cellular response to prolactin)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000660"(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003574(Interleukin-6)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR030473|interpro:IPR030474|rcsb pdb:2L3Y|go:"GO:0051607"(defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|reactome:R-MMU-1059683|go:"GO:0060252"(positive regulation of glial cell proliferation)|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-381426|reactome:R-MMU-8957275|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060664"(epithelial cell proliferation involved in salivary gland morphogenesis)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0070091"(glucagon secretion)|go:"GO:0070092"(regulation of glucagon secretion)	-	-	-	figure legend:Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:3.35x10^7(parameter unit)|koff:2.98x10^-8(molar)	2011/03/24	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:QipydNlQPlQv8mneHmNraOpI33Y10090	intact-crc:126FAEA47BDC6039|rigid:x9Dbz1ET8gW+K6rm0cCWF7PkyEQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00560	uniprotkb:P22272	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-3862989|ensembl:ENSMUSP00000029559	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:il6ra_mouse(display_long)|uniprotkb:Il6ra(gene name)|psi-mi:Il6ra(display_short)|uniprotkb:Il6r(gene name synonym)|uniprotkb:IL-6R 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Stumhofer et al. (2010)	pubmed:21057510|imex:IM-17010	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3863008|imex:IM-17010-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	refseq:NP_034689.2|ensembl:ENSMUSG00000027947(gene)|ensembl:ENSMUST00000029559(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004921"(interleukin-11 receptor activity)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010536"(positive regulation of activation of Janus kinase activity)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019970"(interleukin-11 binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034097"(response to cytokine)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048589"(developmental growth)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070119"(ciliary neurotrophic factor binding)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|interpro:IPR003530(Long hematopoietin receptor, soluble alpha chain, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:3.35x10^7(parameter unit)|koff:2.98x10^-8(molar)	2011/03/24	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:pXUycQrab3Zm8S8wnohZ/q+DvpY10090	intact-crc:126FAEA47BDC6039|rigid:x9Dbz1ET8gW+K6rm0cCWF7PkyEQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)