#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43914	uniprotkb:O43914	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862174|pdbe:2l34|imex:IM-17028-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2D, 2E, 3A, 3C, S2C, S3, Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	intact-crc:B91C7F25DD4D7358|rigid:sj32MitLkujnv6mIE9YGb9cAOtY	false	sufficient binding region:35-67|his tag:n-n|2h label:?-?|13c label:?-?|15n label:?-?	sufficient binding region:35-67|his tag:n-n|2h label:?-?|13c label:?-?|15n label:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-16420154	uniprotkb:O43914	-	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:dap12-tm_nkg2c-tm_fusion_protein(display_short)|psi-mi:EBI-16420154(display_long)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862213|imex:IM-17028-1|wwpdb:2l35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P26717(multiple parent)|uniprotkb:O43914(multiple parent)	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2D, 2E, 3A, 3C, S2C, S3, Table 1.|comment:"A pure disulfide-linked TYROBP transmembrane(TM)-TYROBP(TM)-KLRC2(TM) trimeric peptide product was used in the study."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2017/09/26	rogid:Ede7Exku30nmYMwAi1w0JPcgn8I9606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	intact-crc:0BA76FFB01E0271F|rigid:ASnwb2DbOMzjY42gLG3sXpo3cIs	false	his tag:n-n|2h label:?-?|13c label:?-?|15n label:?-?	sufficient binding region:35-66|his tag:n-n|2h label:?-?|13c label:?-?|15n label:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43914	uniprotkb:O43914	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862316|imex:IM-17028-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	intact-crc:9A3372FD6C22C9F8|rigid:sj32MitLkujnv6mIE9YGb9cAOtY	false	mutation increasing interaction:41-41,45-45,49-49|mutation increasing interaction:50-50,54-54|ha tag:c-c|35s radiolabel:?-?|mutation decreasing interaction:16-16|mutation decreasing interaction:46-47	mutation increasing interaction:41-41,45-45,49-49|mutation increasing interaction:50-50,54-54|ha tag:c-c|35s radiolabel:?-?|mutation decreasing interaction:16-16|mutation decreasing interaction:46-47	2	0	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P09693	uniprotkb:P07766	intact:EBI-3862428|uniprotkb:Q2HIZ6|ensembl:ENSP00000431445	intact:EBI-1211297|uniprotkb:A8K997|intact:EBI-28973315|ensembl:ENSP00000354566	psi-mi:cd3g_human(display_long)|uniprotkb:CD3G(gene name)|psi-mi:CD3G(display_short)|uniprotkb:T3G(gene name synonym)|uniprotkb:T-cell receptor T3 gamma chain(gene name synonym)	psi-mi:cd3e_human(display_long)|uniprotkb:CD3E(gene name)|psi-mi:CD3E(display_short)|uniprotkb:T3E(gene name synonym)|uniprotkb:T-cell surface antigen T3/Leu-4 epsilon chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862425|imex:IM-17028-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719004.1|refseq:NP_000064.1|ensembl:ENSG00000160654(gene)|ensembl:ENST00000532917(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070228"(regulation of lymphocyte apoptotic process)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015484(CD3 gamma and delta chain)|interpro:IPR032052|interpro:IPR036179|rcsb pdb:6JXR|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9664323|reactome:R-HSA-9664422|rcsb pdb:1SY6	refseq:NP_000724.1|ensembl:ENSP00000354566|ensembl:ENSG00000198851(gene)|ensembl:ENST00000361763(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0044297"(cell body)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015484(CD3 gamma and delta chain)|interpro:IPR036179|mint:P07766|rcsb pdb:1A81|rcsb pdb:1SY6|rcsb pdb:1XIW|rcsb pdb:2ROL|rcsb pdb:5QU2|rcsb pdb:6JXR|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948	-	-	-	figure legend:Fig. 5F|caution:TCRb was also co-immunoprecipitated in this experiment but was not included as a participant since the specific cDNA isoform/variable region could not be determined from the article nor from author correspondence|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:39FCsvWYgkx3yxKDNealpdexT/M9606	rogid:9BgUsAHGr15di4bpGeW9UjdzWlE9606	intact-crc:EF3DF3B96E797C96|rigid:iAkHTVu17Mj72wWJV8cxcJHvP8I	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P04234	uniprotkb:P07766	intact:EBI-3862416|uniprotkb:A8MVP6|ensembl:ENSP00000300692	intact:EBI-1211297|uniprotkb:A8K997|intact:EBI-28973315|ensembl:ENSP00000354566	psi-mi:cd3d_human(display_long)|uniprotkb:CD3D(gene name)|psi-mi:CD3D(display_short)|uniprotkb:T3D(gene name synonym)|uniprotkb:T-cell receptor T3 delta chain(gene name synonym)	psi-mi:cd3e_human(display_long)|uniprotkb:CD3E(gene name)|psi-mi:CD3E(display_short)|uniprotkb:T3E(gene name synonym)|uniprotkb:T-cell surface antigen T3/Leu-4 epsilon chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862413|imex:IM-17028-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000723.1|refseq:NP_001035741.1|dip:DIP-42855N|ensembl:ENSG00000167286(gene)|ensembl:ENST00000300692(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045059"(positive thymic T cell selection)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015484(CD3 gamma and delta chain)|interpro:IPR015485(CD3 signaling complex delta subunit)|interpro:IPR032052|interpro:IPR036179|mint:P04234|rcsb pdb:1XIW|rcsb pdb:6JXR|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:XP_016874032.1	refseq:NP_000724.1|ensembl:ENSP00000354566|ensembl:ENSG00000198851(gene)|ensembl:ENST00000361763(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0044297"(cell body)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015484(CD3 gamma and delta chain)|interpro:IPR036179|mint:P07766|rcsb pdb:1A81|rcsb pdb:1SY6|rcsb pdb:1XIW|rcsb pdb:2ROL|rcsb pdb:5QU2|rcsb pdb:6JXR|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948	-	-	-	figure legend:Fig. 5E|caution:TCRa was also co-immunoprecipitated in this experiment but was not included as a participant since the specific cDNA isoform/variable region could not be determined from the article nor from author correspondence|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:pi9sznNgHg/zuYY4xBuDqjF2lNA9606	rogid:9BgUsAHGr15di4bpGeW9UjdzWlE9606	intact-crc:D93395077C03CA71|rigid:N/ZHc5sKJZegMSHKP5LHx6d0ikk	false	35s radiolabel:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q14952	uniprotkb:O43914	intact:EBI-3862286|uniprotkb:O00644|ensembl:ENSP00000479108|ensembl:ENSP00000480969|ensembl:ENSP00000483315|ensembl:ENSP00000491727|ensembl:ENSP00000496477	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:ki2s3_human(display_long)|uniprotkb:KIR2DS3(gene name)|psi-mi:KIR2DS3(display_short)|uniprotkb:NKAT7(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 7(gene name synonym)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862289|imex:IM-17028-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036445.1|ensembl:ENSG00000277163(gene)|ensembl:ENSG00000277657(gene)|ensembl:ENSG00000278306(gene)|ensembl:ENSG00000284039(gene)|ensembl:ENST00000611193(transcript)|ensembl:ENST00000613265(transcript)|ensembl:ENST00000614725(transcript)|ensembl:ENST00000638688(transcript)|ensembl:ENST00000646148(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2C|comment:both DAP12 monomer and dimer were detected in the non-denaturing gel|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:KWNfBkbk2aHDhecgMpHL2XNU8yQ9606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	intact-crc:3C4C27A3D3DAFE67|rigid:iw+W1Xv9m5/OiwS+UECR2g4bXnY	false	35s radiolabel:?-?	mutation decreasing interaction:58-58|ha tag:c-c|35s radiolabel:?-?|mutation decreasing interaction:54-54	-	2	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P26717	uniprotkb:O43914	intact:EBI-3862171|uniprotkb:O43802|uniprotkb:Q52M74|uniprotkb:Q9NR42|ensembl:ENSP00000371327	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:nkg2c_human(display_long)|uniprotkb:KLRC2(gene name)|psi-mi:KLRC2(display_short)|uniprotkb:NKG2C(gene name synonym)|uniprotkb:CD159 antigen-like family member C(gene name synonym)|uniprotkb:NK cell receptor C(gene name synonym)|uniprotkb:NKG2-C-activating NK receptor(gene name synonym)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862258|imex:IM-17028-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002251.2|ensembl:ENSG00000205809(gene)|ensembl:ENST00000381902(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002228"(natural killer cell mediated immunity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0062081"(activating MHC class Ib receptor activity)|go:"GO:1990405"(protein antigen binding)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|rcsb pdb:2L35|reactome:R-HSA-2172127|reactome:R-HSA-2424491|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0023024"(MHC class I protein complex binding)|go:"GO:0030246"(carbohydrate binding)	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2B|comment:both DAP12 monomer and dimer were detected in the non-denaturing gel|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:Yt6xX/Hf1JDgyDegw2HpHIU9LzA9606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	intact-crc:077F8ABE02294002|rigid:nWXAQT/qL1IkNmlJ/DDeLxhfxGc	false	35s radiolabel:?-?	ha tag:c-c|35s radiolabel:?-?|mutation decreasing interaction:54-54|mutation decreasing interaction:58-58	-	2	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P26718	uniprotkb:Q9UBK5	intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4	intact:EBI-2801937|uniprotkb:Q9Y3Y0|uniprotkb:Q9UBS1|ensembl:ENSP00000246551	psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym)	psi-mi:hcst_human(display_long)|uniprotkb:DAP10(gene name synonym)|uniprotkb:KAP10(gene name synonym)|uniprotkb:PIK3AP(gene name synonym)|uniprotkb:DNAX-activation protein 10(gene name synonym)|uniprotkb:Membrane protein DAP10(gene name synonym)|uniprotkb:Transmembrane adapter protein KAP10(gene name synonym)|uniprotkb:UNQ587/PRO1157(orf name)|uniprotkb:HCST(gene name)|psi-mi:HCST(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Call et al. (2010)	pubmed:20890284|imex:IM-17028	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3862381|imex:IM-17028-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N	refseq:NP_001007470.1|refseq:NP_055081.1|ensembl:ENSG00000126264(gene)|ensembl:ENST00000246551(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009986"(cell surface)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0050776"(regulation of immune response)|interpro:IPR009861(DAP10 membrane)|reactome:R-HSA-198933	-	-	-	figure legend:Fig 5D|comment:"native gel on left showed oxidized NKG2D as a defused band, +DTT treatment (right) was performed for quantification of NKG2D proteins."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606	rogid:l3Y4nH5EswUi0NoqaaE0roDqEvQ9606	intact-crc:D2EE05D1A3B92A24|rigid:jqV9veoYkH8qvWruCCvtfPmW5Ck	false	35s radiolabel:?-?	mutation decreasing interaction:57-57|ha tag:c-c|35s radiolabel:?-?	-	2	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)