#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17301 uniprotkb:P11404 intact:EBI-702960|ensembl:ENSP00000296585|uniprotkb:Q14595 intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709 psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym) psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-3504141|imex:IM-15755-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164171(gene)|ensembl:ENST00000296585(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0006971"(hypotonic response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007596"(blood coagulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014075"(response to amine)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033343"(positive regulation of collagen binding)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0038064"(collagen receptor activity)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042493"|go:"GO:0043236"(laminin binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071107"(response to parathyroid hormone)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1PQB|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560 psi-mi:"MI:0469"(intact) - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/06 2014/10/16 rogid:+18cfTauTEyc6MdRfGpHYfDNEpk9606 rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090 intact-crc:64D2FA0576600209|rigid:TbCsFGXREEXvWdb86zF/1U9hW0k false sufficient binding region:1154-1181 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17301 uniprotkb:P11404 intact:EBI-702960|ensembl:ENSP00000296585|uniprotkb:Q14595 intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709 psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym) psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-3504173|imex:IM-15755-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164171(gene)|ensembl:ENST00000296585(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0006971"(hypotonic response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007596"(blood coagulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014075"(response to amine)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033343"(positive regulation of collagen binding)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0038064"(collagen receptor activity)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042493"|go:"GO:0043236"(laminin binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071107"(response to parathyroid hormone)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1PQB|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1a, b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/06 2014/10/16 rogid:+18cfTauTEyc6MdRfGpHYfDNEpk9606 rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090 intact-crc:0CCED78D2D2A7007|rigid:TbCsFGXREEXvWdb86zF/1U9hW0k false sufficient binding region:1154-1181 sufficient binding region:9-133 - - psi-mi:"MI:0823"(predetermined feature) psi-mi:"MI:0823"(predetermined feature) uniprotkb:P56199 uniprotkb:P11404 intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588 intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709 psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym) psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-3504204|imex:IM-15755-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852478.1|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042311"(vasodilation)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045123"(cellular extravasation)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|go:"GO:0034665"(integrin alpha1-beta1 complex)|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|ensembl:ENSG00000213949(gene)|ensembl:ENST00000282588(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|dip:DIP-206N refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1a, b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/06 2014/10/16 rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606 rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090 intact-crc:4E86D6B6DA4573E9|rigid:qLSbKQ/qoH3qNXOzW7QiwTzQfmo false sufficient binding region:1164-1179 sufficient binding region:9-133 - - psi-mi:"MI:0823"(predetermined feature) psi-mi:"MI:0823"(predetermined feature) uniprotkb:O75578 uniprotkb:P11404 intact:EBI-2567971|uniprotkb:B2RAM4|uniprotkb:Q6UXJ6|uniprotkb:Q9UHZ8|ensembl:ENSP00000358310|uniprotkb:B2RTV5 intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709 psi-mi:ita10_human(display_long)|uniprotkb:ITGA10(gene name)|psi-mi:ITGA10(display_short)|uniprotkb:UNQ468/PRO827(orf name) psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-3504221|imex:IM-15755-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003628.2|ensembl:ENSG00000143127(gene)|ensembl:ENST00000369304(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|refseq:NP_001289969.1|refseq:NP_001289970.1|go:"GO:0046872"(metal ion binding)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|reactome:R-HSA-216083|reactome:R-HSA-447041|reactome:R-HSA-75892 refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1a, b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/06 2014/10/16 rogid:kxABiDsnfUZg5Y1KNaqgm+oFyqg9606 rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090 intact-crc:9C93545A10D1166E|rigid:ZgYtXLAnPA5M2OMN7pgcXhtlVn8 false sufficient binding region:1145-1167 sufficient binding region:9-133 - - psi-mi:"MI:0823"(predetermined feature) psi-mi:"MI:0823"(predetermined feature) uniprotkb:Q9UKX5 uniprotkb:P11404 intact:EBI-2568019|uniprotkb:Q8WYI8|uniprotkb:Q9UKQ1|ensembl:ENSP00000327290|uniprotkb:J3KQM2 intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709 psi-mi:ita11_human(display_long)|uniprotkb:ITGA11(gene name)|psi-mi:ITGA11(display_short)|uniprotkb:MSTP018(orf name) psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-3504229|imex:IM-15755-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001004439.1|ensembl:ENSG00000137809(gene)|ensembl:ENST00000315757(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007517"(muscle organ development)|go:"GO:0008305"(integrin complex)|go:"GO:0016020"(membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0038064"(collagen receptor activity)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|reactome:R-HSA-216083 refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1a, b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/01/06 2014/10/16 rogid:tFyxZTYEQ8Mo17+AUVUWFioPgFo9606 rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090 intact-crc:27EA51147066381C|rigid:Dr+dp1gVdCbssLfvVxU42LNPfIc false sufficient binding region:1164-1188 sufficient binding region:9-133 - - psi-mi:"MI:0823"(predetermined feature) psi-mi:"MI:0823"(predetermined feature) uniprotkb:P05413 uniprotkb:P17301 intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817 intact:EBI-702960|ensembl:ENSP00000296585|uniprotkb:Q14595 psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym) psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1262"(I2D) intact:EBI-3504246|imex:IM-15755-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560 ensembl:ENSG00000164171(gene)|ensembl:ENST00000296585(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0006971"(hypotonic response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007596"(blood coagulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014075"(response to amine)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033343"(positive regulation of collagen binding)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0038064"(collagen receptor activity)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042493"|go:"GO:0043236"(laminin binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071107"(response to parathyroid hormone)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1PQB|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/06 2014/10/16 rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606 rogid:+18cfTauTEyc6MdRfGpHYfDNEpk9606 intact-crc:01EE97E45A6DAC59|rigid:0ZurO9uKL3dIxzdhuFiQMclVwXE false - sufficient binding region:1154-1166 - - psi-mi:"MI:0823"(predetermined feature) psi-mi:"MI:0823"(predetermined feature) uniprotkb:P56199 uniprotkb:P05413 intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588 intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817 psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym) psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1262"(I2D) intact:EBI-3504254|imex:IM-15755-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852478.1|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042311"(vasodilation)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045123"(cellular extravasation)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|go:"GO:0034665"(integrin alpha1-beta1 complex)|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|ensembl:ENSG00000213949(gene)|ensembl:ENST00000282588(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|dip:DIP-206N refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/06 2014/10/16 rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606 rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606 intact-crc:610FB30BF4814A34|rigid:jgwmAu7taXn1F0Qh3zOj8uYXm9Y false sufficient binding region:1164-1179 - - - psi-mi:"MI:0823"(predetermined feature) psi-mi:"MI:0823"(predetermined feature) uniprotkb:P05556 uniprotkb:P05413 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817 psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1262"(I2D) intact:EBI-3504274|imex:IM-15755-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1d|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_468)|taxid:9606(Homo sapiens MDA-MB-468) - 2011/01/06 2014/10/16 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606 intact-crc:6E8C289E11D674C2|rigid:Axb7F6pla6rIBOE9yZq+cVg+xjw false - enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P05413 uniprotkb:P05556 intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:1262"(I2D) intact:EBI-3504312|imex:IM-15755-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560 go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 go:"GO:0005886"(plasma membrane) - - figure legend:Fig. 2a, S2b, 3e|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2011/01/06 2014/10/16 rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 intact-crc:3C1B706EAA31E605|rigid:Axb7F6pla6rIBOE9yZq+cVg+xjw false enhanced green fluorescent protein tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P08648 uniprotkb:P05413 intact:EBI-1382311|uniprotkb:Q96HA5|ensembl:ENSP00000293379 intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817 psi-mi:ita5_human(display_long)|uniprotkb:ITGA5(gene name)|psi-mi:ITGA5(display_short)|uniprotkb:FNRA(gene name synonym)|uniprotkb:Fibronectin receptor subunit alpha(gene name synonym)|uniprotkb:Integrin alpha-F(gene name synonym)|uniprotkb:VLA-5(gene name synonym)|uniprotkb:CD49 antigen-like family member E(gene name synonym) psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:1262"(I2D) intact:EBI-3504320|imex:IM-15755-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002196.4|dip:DIP-40037N|ensembl:ENSG00000161638(gene)|ensembl:ENST00000293379(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P08648|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-445144|reactome:R-HSA-8941332 refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560 go:"GO:0005886"(plasma membrane) - - figure legend:Fig. 2b, S2b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2011/01/06 2014/10/16 rogid:Wv2ronpU6TmRP0kwlWisA2ObEbI9606 rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606 intact-crc:76F9B9D521BF4EA1|rigid:5i4/VzcwQCMPN8Ov6z+HQvo4NWs false - enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P16144 uniprotkb:P05413 intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97 intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817 psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short) psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Nevo et al. (2010) pubmed:20802519|imex:IM-15755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:1262"(I2D) intact:EBI-3504327|imex:IM-15755-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1 refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560 go:"GO:0005886"(plasma membrane) - - figure legend:Fig. 2c, S2b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2011/01/06 2014/10/16 rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606 rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606 intact-crc:F8D779A66A28AE08|rigid:VzAB/j9W/LdfLBDIcWGOk3gBRoc false - enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)