#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P36941	uniprotkb:P36941	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372508|imex:IM-17035-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/08/23	2014/10/16	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:97BD703A2E065808|rigid:LtBUaIjK/9Y5vlvxM/XC070wHa8	false	experimental feature:249-435	experimental feature:249-435	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15326	uniprotkb:P36941	intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372502|imex:IM-17035-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/08/23	2014/10/16	rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:6D5911462D331086|rigid:kp4a3AylraZDuTkxmfuyG3PT7iA	false	-	experimental feature:249-435	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15326	uniprotkb:P36941	intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372516|imex:IM-17035-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:1a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/08/23	2014/10/16	rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:1C3249CA14B1F0CC|rigid:kp4a3AylraZDuTkxmfuyG3PT7iA	false	experimental feature:486-602	experimental feature:249-435|sufficient binding region:336-397|sufficient binding region:398-435	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13114	uniprotkb:P36941	intact:EBI-357631|uniprotkb:Q12990|uniprotkb:Q13076|uniprotkb:Q13947|uniprotkb:Q6AZX1|uniprotkb:Q9UNL1|ensembl:ENSP00000376500|ensembl:ENSP00000454207|uniprotkb:B7Z8C4	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:traf3_human(display_long)|uniprotkb:TRAF3(gene name)|psi-mi:TRAF3(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:CRAF1(gene name synonym)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:CD40-binding protein(gene name synonym)|uniprotkb:LMP1-associated protein 1(gene name synonym)|uniprotkb:CAP-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372636|imex:IM-17035-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131323(gene)|ensembl:ENST00000392745(transcript)|ensembl:ENST00000560371(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|refseq:NP_001186356.1|refseq:NP_003291.2|refseq:NP_663777.1|refseq:NP_663778.1|go:"GO:0007165"(signal transduction)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q13114|go:"GO:0042981"(regulation of apoptotic process)|rcsb pdb:1FLK|rcsb pdb:1FLL|rcsb pdb:1L0A|rcsb pdb:1RF3|rcsb pdb:1ZMS|rcsb pdb:2ECY|rcsb pdb:2GKW|rcsb pdb:1KZZ|refseq:XP_011535420.1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|reactome:R-HSA-5689896|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-5602571|refseq:XP_016877106.1|refseq:XP_016877107.1|dip:DIP-6222N	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:3b|antagonist:"Coexpression with ha-zmynd11 (BRAM!) disrupts the interaction in a dose-dependent manner."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/08/23	2014/10/16	rogid:9Tjx/USypDBBrPVyFOsLzM/bwzA9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:F4F5BE7875555CB1|rigid:mUsjxt4w9jiWC7wMFR/s4ggDznA	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12933	uniprotkb:P36941	intact:EBI-355744|uniprotkb:Q96NT2|uniprotkb:A8K107|uniprotkb:B4DPJ7|uniprotkb:Q7Z337|intact:EBI-1046651|ensembl:ENSP00000247668	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:traf2_human(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372617|imex:IM-17035-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066961.2|refseq:XP_011517279.1|refseq:XP_011517280.1|refseq:XP_011517276.1|refseq:XP_011517277.1|refseq:XP_011517278.1|ensembl:ENSG00000127191(gene)|ensembl:ENST00000247668(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002947"(tumor necrosis factor receptor superfamily complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005174"(CD40 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027133|interpro:IPR032070|interpro:IPR037305|interpro:IPR043211|mint:Q12933|rcsb pdb:1CA4|rcsb pdb:1CA9|rcsb pdb:1CZY|rcsb pdb:1CZZ|rcsb pdb:1D00|rcsb pdb:1D01|rcsb pdb:1D0A|rcsb pdb:1D0J|rcsb pdb:1F3V|rcsb pdb:1QSC|rcsb pdb:3KNV|rcsb pdb:3M06|rcsb pdb:3M0A|rcsb pdb:3M0D|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-9693928|refseq:XP_016870584.1|dip:DIP-6223N	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:3a|comment:"Coexpression with ha-zmynd11 (BRAM1) disrupts the interaction in a dose-dependent manner."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/08/23	2014/10/16	rogid:JhaoM5kRLh3zwhXr+BsCCRNOYa09606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:770590FF4950C19F|rigid:2un4G/nJ/Ecq6kqCJ+xsocEXR/8	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15326	uniprotkb:P36941	intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372592|imex:IM-17035-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:2 and 3b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/08/23	2014/10/16	rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:F1DC408D7BD6FD7D|rigid:kp4a3AylraZDuTkxmfuyG3PT7iA	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P36941	uniprotkb:P36941	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372600|imex:IM-17035-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:2|antagonist:"Coexpression with ha-zmynd11 (BRAM1) disrupts the interaction in a dose-dependent manner."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/08/23	2014/10/16	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:B6D123E30B7813B8|rigid:LtBUaIjK/9Y5vlvxM/XC070wHa8	false	myc tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15326	uniprotkb:P36941	intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372609|imex:IM-17035-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:3a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/08/23	2014/10/16	rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:E41F308561E81A2D|rigid:kp4a3AylraZDuTkxmfuyG3PT7iA	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15326	uniprotkb:P36941	intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372537|imex:IM-17035-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/08/23	2014/10/16	rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:FB31FCDCE7DFD63D|rigid:kp4a3AylraZDuTkxmfuyG3PT7iA	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75398	uniprotkb:P36941	intact:EBI-718185|uniprotkb:O15152|uniprotkb:O75399|uniprotkb:O75510|uniprotkb:O75511|uniprotkb:O75512|uniprotkb:O75513|uniprotkb:Q9UET1|uniprotkb:A8K5R8|uniprotkb:A8K1F8|uniprotkb:C7T5V5|intact:EBI-28974412|ensembl:ENSP00000371846	intact:EBI-3509981|intact:EBI-10982154|uniprotkb:D3DUR2|uniprotkb:B7Z1D2|uniprotkb:F5GXE7|ensembl:ENSP00000228918	psi-mi:deaf1_human(display_long)|uniprotkb:Nuclear DEAF-1-related transcriptional regulator(gene name synonym)|uniprotkb:Suppressin(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 5(gene name synonym)|uniprotkb:DEAF1(gene name)|psi-mi:DEAF1(display_short)|uniprotkb:SPN(gene name synonym)|uniprotkb:ZMYND5(gene name synonym)	psi-mi:tnr3_human(display_long)|uniprotkb:LTBR(gene name)|psi-mi:LTBR(display_short)|uniprotkb:D12S370(gene name synonym)|uniprotkb:TNFCR(gene name synonym)|uniprotkb:TNFR3(gene name synonym)|uniprotkb:TNFRSF3(gene name synonym)|uniprotkb:Lymphotoxin-beta receptor(gene name synonym)|uniprotkb:Tumor necrosis factor C receptor(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2-related protein(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2011)	pubmed:20732415|imex:IM-17035	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4372571|imex:IM-17035-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066288.2|ensembl:ENSP00000371846|refseq:NP_001280563.1|ensembl:ENSG00000177030(gene)|ensembl:ENST00000382409(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001843"(neural tube closure)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR000770(SAND)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR010919(SAND-like)|interpro:IPR024119|mint:O75398|rcsb pdb:2JW6|rcsb pdb:4A24|rcsb pdb:5UWW	dip:DIP-2928N|refseq:NP_002333.1|refseq:NP_001257916.1|ensembl:ENSG00000111321(gene)|ensembl:ENST00000228918(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR017349(Tumour necrosis factor receptor superfamily member 3)|interpro:IPR033997|mint:P36941|rcsb pdb:1RF3|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594	-	-	-	figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/08/23	2014/10/16	rogid:2wVDKJ2CcROUYc5whZI3JWATnI89606	rogid:Ekl/gGxXT2EmjWLJpZEBmMpxYYw9606	intact-crc:67C8AFFDEE2F1C4F|rigid:5sdzI+uQXtyBdXP1Sl0BJIqy0oY	false	experimental feature:404-565|flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)