#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BZR6 uniprotkb:Q8IZA0 intact:EBI-5240240|uniprotkb:D3DX28|ensembl:ENSP00000043402 intact:EBI-5240269|uniprotkb:B1AN13|uniprotkb:D3DPR8|uniprotkb:O95010|uniprotkb:Q6PJJ7|uniprotkb:Q7L1C9|uniprotkb:Q8N2B3|uniprotkb:Q8NDA0|uniprotkb:Q8WY39|uniprotkb:Q8WYZ5|uniprotkb:Q96IC3|uniprotkb:Q96JJ0|uniprotkb:Q9BUW6|uniprotkb:Q9H7V0|ensembl:ENSP00000318406 psi-mi:rtn4r_human(display_long)|uniprotkb:RTN4R(gene name)|psi-mi:RTN4R(display_short)|uniprotkb:NOGOR(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym)|uniprotkb:UNQ330/PRO526(orf name) psi-mi:k319l_human(display_long)|uniprotkb:KIAA0319L(gene name)|psi-mi:KIAA0319L(display_short)|uniprotkb:KIAA1837(gene name synonym)|uniprotkb:PP791(orf name)|uniprotkb:AAVR(gene name synonym)|uniprotkb:Adeno-associated virus receptor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Poon et al. (2011) pubmed:20697954|imex:IM-16980 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-5240450|imex:IM-16980-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075380.1|ensembl:ENSG00000040608(gene)|ensembl:ENST00000043402(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:1OZN|rcsb pdb:1P8T|reactome:R-HSA-193634 refseq:XP_011540481.1|refseq:NP_079150.3|refseq:XP_006710970.1|refseq:XP_006710972.1|refseq:XP_006710973.1|refseq:XP_016857867.1|ensembl:ENSG00000142687(gene)|ensembl:ENST00000325722(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR000601(PKD)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013980(Seven cysteines)|interpro:IPR022409|interpro:IPR029865|interpro:IPR035986|rcsb pdb:2YRL|rcsb pdb:6IHB|rcsb pdb:6JCQ|rcsb pdb:6JCS|rcsb pdb:6NZ0|rcsb pdb:7KPN|refseq:XP_016857865.1 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/11/01 2014/10/16 rogid:KzyySuqIDgFlEOepobQQBgItepQ9606 rogid:TIMGWLizfeISNvV9s/796eq6FQI9606 intact-crc:37C4BDC0B83BE57E|rigid:jGxcxm5uXY8vZY6wr79S11UjLP0 false - sufficient binding region:1-929 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IZA0 uniprotkb:Q9BZR6 intact:EBI-5240269|uniprotkb:B1AN13|uniprotkb:D3DPR8|uniprotkb:O95010|uniprotkb:Q6PJJ7|uniprotkb:Q7L1C9|uniprotkb:Q8N2B3|uniprotkb:Q8NDA0|uniprotkb:Q8WY39|uniprotkb:Q8WYZ5|uniprotkb:Q96IC3|uniprotkb:Q96JJ0|uniprotkb:Q9BUW6|uniprotkb:Q9H7V0|ensembl:ENSP00000318406 intact:EBI-5240240|uniprotkb:D3DX28|ensembl:ENSP00000043402 psi-mi:k319l_human(display_long)|uniprotkb:KIAA0319L(gene name)|psi-mi:KIAA0319L(display_short)|uniprotkb:KIAA1837(gene name synonym)|uniprotkb:PP791(orf name)|uniprotkb:AAVR(gene name synonym)|uniprotkb:Adeno-associated virus receptor(gene name synonym) psi-mi:rtn4r_human(display_long)|uniprotkb:RTN4R(gene name)|psi-mi:RTN4R(display_short)|uniprotkb:NOGOR(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym)|uniprotkb:UNQ330/PRO526(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Poon et al. (2011) pubmed:20697954|imex:IM-16980 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-5240465|imex:IM-16980-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540481.1|refseq:NP_079150.3|refseq:XP_006710970.1|refseq:XP_006710972.1|refseq:XP_006710973.1|refseq:XP_016857867.1|ensembl:ENSG00000142687(gene)|ensembl:ENST00000325722(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR000601(PKD)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013980(Seven cysteines)|interpro:IPR022409|interpro:IPR029865|interpro:IPR035986|rcsb pdb:2YRL|rcsb pdb:6IHB|rcsb pdb:6JCQ|rcsb pdb:6JCS|rcsb pdb:6NZ0|rcsb pdb:7KPN|refseq:XP_016857865.1 refseq:NP_075380.1|ensembl:ENSG00000040608(gene)|ensembl:ENST00000043402(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:1OZN|rcsb pdb:1P8T|reactome:R-HSA-193634 - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/11/01 2014/10/16 rogid:TIMGWLizfeISNvV9s/796eq6FQI9606 rogid:KzyySuqIDgFlEOepobQQBgItepQ9606 intact-crc:3A17EA912D15F64E|rigid:jGxcxm5uXY8vZY6wr79S11UjLP0 false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BZR6 uniprotkb:Q8IZA0 intact:EBI-5240240|uniprotkb:D3DX28|ensembl:ENSP00000043402 intact:EBI-5240269|uniprotkb:B1AN13|uniprotkb:D3DPR8|uniprotkb:O95010|uniprotkb:Q6PJJ7|uniprotkb:Q7L1C9|uniprotkb:Q8N2B3|uniprotkb:Q8NDA0|uniprotkb:Q8WY39|uniprotkb:Q8WYZ5|uniprotkb:Q96IC3|uniprotkb:Q96JJ0|uniprotkb:Q9BUW6|uniprotkb:Q9H7V0|ensembl:ENSP00000318406 psi-mi:rtn4r_human(display_long)|uniprotkb:RTN4R(gene name)|psi-mi:RTN4R(display_short)|uniprotkb:NOGOR(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym)|uniprotkb:UNQ330/PRO526(orf name) psi-mi:k319l_human(display_long)|uniprotkb:KIAA0319L(gene name)|psi-mi:KIAA0319L(display_short)|uniprotkb:KIAA1837(gene name synonym)|uniprotkb:PP791(orf name)|uniprotkb:AAVR(gene name synonym)|uniprotkb:Adeno-associated virus receptor(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Poon et al. (2011) pubmed:20697954|imex:IM-16980 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-5240482|imex:IM-16980-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075380.1|ensembl:ENSG00000040608(gene)|ensembl:ENST00000043402(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:1OZN|rcsb pdb:1P8T|reactome:R-HSA-193634 refseq:XP_011540481.1|refseq:NP_079150.3|refseq:XP_006710970.1|refseq:XP_006710972.1|refseq:XP_006710973.1|refseq:XP_016857867.1|ensembl:ENSG00000142687(gene)|ensembl:ENST00000325722(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR000601(PKD)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013980(Seven cysteines)|interpro:IPR022409|interpro:IPR029865|interpro:IPR035986|rcsb pdb:2YRL|rcsb pdb:6IHB|rcsb pdb:6JCQ|rcsb pdb:6JCS|rcsb pdb:6NZ0|rcsb pdb:7KPN|refseq:XP_016857865.1 go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-brain-cortex)|taxid:9606(Homo sapiens brain cortex) - 2011/11/01 2014/10/16 rogid:KzyySuqIDgFlEOepobQQBgItepQ9606 rogid:TIMGWLizfeISNvV9s/796eq6FQI9606 intact-crc:8DB0B4E9B17EB1E7|rigid:jGxcxm5uXY8vZY6wr79S11UjLP0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IZA0 uniprotkb:Q9BZR6 intact:EBI-5240269|uniprotkb:B1AN13|uniprotkb:D3DPR8|uniprotkb:O95010|uniprotkb:Q6PJJ7|uniprotkb:Q7L1C9|uniprotkb:Q8N2B3|uniprotkb:Q8NDA0|uniprotkb:Q8WY39|uniprotkb:Q8WYZ5|uniprotkb:Q96IC3|uniprotkb:Q96JJ0|uniprotkb:Q9BUW6|uniprotkb:Q9H7V0|ensembl:ENSP00000318406 intact:EBI-5240240|uniprotkb:D3DX28|ensembl:ENSP00000043402 psi-mi:k319l_human(display_long)|uniprotkb:KIAA0319L(gene name)|psi-mi:KIAA0319L(display_short)|uniprotkb:KIAA1837(gene name synonym)|uniprotkb:PP791(orf name)|uniprotkb:AAVR(gene name synonym)|uniprotkb:Adeno-associated virus receptor(gene name synonym) psi-mi:rtn4r_human(display_long)|uniprotkb:RTN4R(gene name)|psi-mi:RTN4R(display_short)|uniprotkb:NOGOR(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym)|uniprotkb:UNQ330/PRO526(orf name) psi-mi:"MI:0018"(two hybrid) Poon et al. (2011) pubmed:20697954|imex:IM-16980 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-5240303|imex:IM-16980-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540481.1|refseq:NP_079150.3|refseq:XP_006710970.1|refseq:XP_006710972.1|refseq:XP_006710973.1|refseq:XP_016857867.1|ensembl:ENSG00000142687(gene)|ensembl:ENST00000325722(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR000601(PKD)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013980(Seven cysteines)|interpro:IPR022409|interpro:IPR029865|interpro:IPR035986|rcsb pdb:2YRL|rcsb pdb:6IHB|rcsb pdb:6JCQ|rcsb pdb:6JCS|rcsb pdb:6NZ0|rcsb pdb:7KPN|refseq:XP_016857865.1 refseq:NP_075380.1|ensembl:ENSG00000040608(gene)|ensembl:ENST00000043402(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:1OZN|rcsb pdb:1P8T|reactome:R-HSA-193634 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/11/01 2014/10/16 rogid:TIMGWLizfeISNvV9s/796eq6FQI9606 rogid:KzyySuqIDgFlEOepobQQBgItepQ9606 intact-crc:C7A666612D1A3C88|rigid:jGxcxm5uXY8vZY6wr79S11UjLP0 false sufficient binding region:1-929 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)