#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UEW8	uniprotkb:P15529	intact:EBI-2680974|uniprotkb:Q9UER4|uniprotkb:O14774|uniprotkb:Q53S90|uniprotkb:Q53SL7|uniprotkb:Q53SS1|ensembl:ENSP00000348278|uniprotkb:X5D9C8	intact:EBI-2623451|uniprotkb:A0T1T0|uniprotkb:A0T1T1|uniprotkb:Q9UCJ4|uniprotkb:Q5VWS7|uniprotkb:Q5VWT1|uniprotkb:Q7Z3R5|uniprotkb:Q9NNW2|uniprotkb:Q6N0A1|uniprotkb:Q5VWS6|uniprotkb:Q5VWS8|uniprotkb:A0T1T2|uniprotkb:Q9NNW3|uniprotkb:Q5HY94|uniprotkb:Q5VWS9|uniprotkb:Q53GV9|uniprotkb:Q15429|uniprotkb:Q9NNW4|uniprotkb:Q5VWT0|uniprotkb:Q5VWT2|ensembl:ENSP00000350893	psi-mi:stk39_human(display_long)|uniprotkb:SPAK(gene name synonym)|uniprotkb:DCHT(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:STK39(gene name)|psi-mi:STK39(display_short)	psi-mi:mcp_human(display_long)|uniprotkb:MCP(gene name synonym)|uniprotkb:MIC10(gene name synonym)|uniprotkb:TLX(gene name synonym)|uniprotkb:Trophoblast leukocyte common antigen(gene name synonym)|uniprotkb:CD46(gene name)|psi-mi:CD46(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cardone et al. (2010)	pubmed:20694009|imex:IM-17024	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3842451|imex:IM-17024-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037365.2|ensembl:ENSG00000198648(gene)|ensembl:ENST00000355999(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)	refseq:XP_011507865.1|refseq:XP_011507866.1|refseq:NP_002380.3|refseq:NP_722548.1|refseq:NP_758860.1|refseq:NP_758861.1|refseq:NP_758862.1|refseq:NP_758863.1|refseq:NP_758869.1|refseq:NP_758871.1|refseq:XP_016856797.1|refseq:XP_016856798.1|refseq:XP_016856799.1|ensembl:ENSG00000117335(gene)|ensembl:ENST00000358170(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002079"(inner acrosomal membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0007338"(single fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0035581"(sequestering of extracellular ligand from receptor)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0045959"(negative regulation of complement activation, classical pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR017341(Membrane cofactor protein, CD46)|interpro:IPR035976|rcsb pdb:1CKL|rcsb pdb:1HR4|rcsb pdb:2O39|rcsb pdb:3INB|rcsb pdb:3L89|rcsb pdb:3O8E|rcsb pdb:5FO8|reactome:R-HSA-977606|dip:DIP-41232N|uniprotkb:P15529-11(identity)|uniprotkb:P15529-3(identity)|uniprotkb:P15529-12(identity)|uniprotkb:P15529-4(identity)	-	-	-	figure legend:Fig. 4B|isoform-comment:Ab used to IP mcp detected isoforms BC1, BC2, C1, C2. See Xref to Uniprot under mcp.|agonist:anti-CD46|antagonist:anti-CD3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t-cell)|taxid:9606(Homo sapiens)	-	2011/03/15	2014/10/16	rogid:472OT0D4ddZoxjICU4UOhTOJ4Oo9606	rogid:nhB+pnkhLRsOA01ekJ50pkUu3og9606	intact-crc:53225410DB31C08E|rigid:TKWvj2lM+uRXKkiwl21gKgc+XMk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)