#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00165	uniprotkb:Q14451	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Siamakpour-Reihani et al. (2011)	pubmed:20665473	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4288461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	-	-	-	figure legend:fig 2 and fig 3|comment:contacted author to make sure it is human GRB7, even though residue numbering shown matches mouse|curation depth:mimix curation|curation depth:mimix curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2011/06/21	2014/10/16	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	intact-crc:88FA8E2159085B95|rigid:5HEJ134cQuoEi6/RBnxf87vAsrM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14451	uniprotkb:O00165	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Siamakpour-Reihani et al. (2011)	pubmed:20665473	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4302634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165	-	-	-	comment:"no figure, but detailed description in Methods (p.315) and mentioned in first paragraph of results  section (p.317)"|curation depth:mimix curation|curation depth:mimix curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/06/21	2014/10/16	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:AD0F4B277BE965FB|rigid:5HEJ134cQuoEi6/RBnxf87vAsrM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)