#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61006 uniprotkb:Q18PE0 intact:EBI-3989087|uniprotkb:Q61005|uniprotkb:Q61987|uniprotkb:Q61988|ensembl:ENSMUSP00000081625 intact:EBI-3989091|uniprotkb:Q3TCZ6|uniprotkb:Q5FW70|uniprotkb:Q8C8U7|ensembl:ENSMUSP00000109909 psi-mi:musk_mouse(display_long)|uniprotkb:Musk(gene name)|psi-mi:Musk(display_short)|uniprotkb:Nsk2(gene name synonym)|uniprotkb:Muscle-specific tyrosine-protein kinase receptor(gene name synonym) psi-mi:dok7_mouse(display_long)|uniprotkb:Dok7(gene name)|psi-mi:Dok7(display_short)|uniprotkb:Downstream of tyrosine kinase 7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Bergamin et al. (2010) pubmed:20603078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3989135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001032205.1|refseq:NP_001032206.1|refseq:NP_001032207.1|refseq:NP_035074.2|ensembl:ENSMUSG00000057280(gene)|ensembl:ENSMUST00000084578(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007613"(memory)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:2000541"(positive regulation of protein geranylgeranylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020067|interpro:IPR020635|interpro:IPR036179|interpro:IPR036790|rcsb pdb:3ML4|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation) ensembl:ENSMUST00000114270(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037746|interpro:IPR037747|interpro:IPR037748|rcsb pdb:3ML4|ensembl:ENSMUSG00000044716(gene)|refseq:XP_006503961.1|refseq:XP_006503963.1|refseq:NP_001335203.1|refseq:NP_001335204.1|refseq:NP_001335205.1|refseq:NP_001335407.1 - - - figure legend:supplementary fig S1|comment:for the synthetic peptide, residue numbering fits mouse|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/10 2014/10/16 rogid:KN1YzYVoSsqXex4SJYxTghIOSx810090 rogid:w+7hKI6fLh7Cya6HBK9Y7EuwlQQ10090 intact-crc:1BCDEFAAD573C440|rigid:7LGIQ7esGkfF8v8bbJFwF4rWVOI false sufficient binding region:544-556 sufficient binding region:1-220 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18PE0 uniprotkb:Q61006 intact:EBI-3989091|uniprotkb:Q3TCZ6|uniprotkb:Q5FW70|uniprotkb:Q8C8U7|ensembl:ENSMUSP00000109909 intact:EBI-3989087|uniprotkb:Q61005|uniprotkb:Q61987|uniprotkb:Q61988|ensembl:ENSMUSP00000081625 psi-mi:dok7_mouse(display_long)|uniprotkb:Dok7(gene name)|psi-mi:Dok7(display_short)|uniprotkb:Downstream of tyrosine kinase 7(gene name synonym) psi-mi:musk_mouse(display_long)|uniprotkb:Musk(gene name)|psi-mi:Musk(display_short)|uniprotkb:Nsk2(gene name synonym)|uniprotkb:Muscle-specific tyrosine-protein kinase receptor(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Bergamin et al. (2010) pubmed:20603078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3989090|pdbe:3ML4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000114270(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037746|interpro:IPR037747|interpro:IPR037748|rcsb pdb:3ML4|ensembl:ENSMUSG00000044716(gene)|refseq:XP_006503961.1|refseq:XP_006503963.1|refseq:NP_001335203.1|refseq:NP_001335204.1|refseq:NP_001335205.1|refseq:NP_001335407.1 refseq:NP_001032205.1|refseq:NP_001032206.1|refseq:NP_001032207.1|refseq:NP_035074.2|ensembl:ENSMUSG00000057280(gene)|ensembl:ENSMUST00000084578(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007613"(memory)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:2000541"(positive regulation of protein geranylgeranylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020067|interpro:IPR020635|interpro:IPR036179|interpro:IPR036790|rcsb pdb:3ML4|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation) - - - 3d-resolution:2.6 A|3d-r-factors:R factor 0.255 R free 0.302|comment:for the synthetic peptide, residue numbering fits mouse|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/10 2014/10/16 rogid:w+7hKI6fLh7Cya6HBK9Y7EuwlQQ10090 rogid:KN1YzYVoSsqXex4SJYxTghIOSx810090 intact-crc:839C035114462121|rigid:7LGIQ7esGkfF8v8bbJFwF4rWVOI false sufficient binding region:1-220 sufficient binding region:544-556 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18PE0 uniprotkb:Q18PE0 intact:EBI-3989091|uniprotkb:Q3TCZ6|uniprotkb:Q5FW70|uniprotkb:Q8C8U7|ensembl:ENSMUSP00000109909 intact:EBI-3989091|uniprotkb:Q3TCZ6|uniprotkb:Q5FW70|uniprotkb:Q8C8U7|ensembl:ENSMUSP00000109909 psi-mi:dok7_mouse(display_long)|uniprotkb:Dok7(gene name)|psi-mi:Dok7(display_short)|uniprotkb:Downstream of tyrosine kinase 7(gene name synonym) psi-mi:dok7_mouse(display_long)|uniprotkb:Dok7(gene name)|psi-mi:Dok7(display_short)|uniprotkb:Downstream of tyrosine kinase 7(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Bergamin et al. (2010) pubmed:20603078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3989099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000114270(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037746|interpro:IPR037747|interpro:IPR037748|rcsb pdb:3ML4|ensembl:ENSMUSG00000044716(gene)|refseq:XP_006503961.1|refseq:XP_006503963.1|refseq:NP_001335203.1|refseq:NP_001335204.1|refseq:NP_001335205.1|refseq:NP_001335407.1 ensembl:ENSMUST00000114270(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037746|interpro:IPR037747|interpro:IPR037748|rcsb pdb:3ML4|ensembl:ENSMUSG00000044716(gene)|refseq:XP_006503961.1|refseq:XP_006503963.1|refseq:NP_001335203.1|refseq:NP_001335204.1|refseq:NP_001335205.1|refseq:NP_001335407.1 - - - 3d-resolution:2.6 A|comment:"monomer in solution, dimer (tetramer?) in crystal. Authors speculate the protein may dimerize upon MUSK binding. See also text p.103 and Fig 3"|caution:This crystal was described in the article but not deposited with PDB, as only partially refined.|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/10 2014/10/16 rogid:w+7hKI6fLh7Cya6HBK9Y7EuwlQQ10090 rogid:w+7hKI6fLh7Cya6HBK9Y7EuwlQQ10090 intact-crc:63CBDA35317EE16F|rigid:xuM1wf3LrEarRyT4sP99aF0qGbU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18PE0 uniprotkb:Q62838 intact:EBI-3989091|uniprotkb:Q3TCZ6|uniprotkb:Q5FW70|uniprotkb:Q8C8U7|ensembl:ENSMUSP00000109909 intact:EBI-2106354 psi-mi:dok7_mouse(display_long)|uniprotkb:Dok7(gene name)|psi-mi:Dok7(display_short)|uniprotkb:Downstream of tyrosine kinase 7(gene name synonym) psi-mi:musk_rat(display_long)|uniprotkb:Musk(gene name)|psi-mi:Musk(display_short)|uniprotkb:Muscle-specific tyrosine protein kinase receptor(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bergamin et al. (2010) pubmed:20603078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3989118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000114270(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037746|interpro:IPR037747|interpro:IPR037748|rcsb pdb:3ML4|ensembl:ENSMUSG00000044716(gene)|refseq:XP_006503961.1|refseq:XP_006503963.1|refseq:NP_001335203.1|refseq:NP_001335204.1|refseq:NP_001335205.1|refseq:NP_001335407.1 rgd:3211|refseq:NP_112323.1|interpro:IPR020067|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|rcsb pdb:1LUF|rcsb pdb:2IEP|rcsb pdb:3HKL|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR036179|interpro:IPR036790|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007613"(memory)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090102"(cochlea development)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:2000541"(positive regulation of protein geranylgeranylation) - - - figure legend:Fig 3A|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/10 2014/10/16 rogid:w+7hKI6fLh7Cya6HBK9Y7EuwlQQ10090 rogid:NV3O9XtmNH+jheY8vIiWBVHed8s10116 intact-crc:DAAE2C226B304F2B|rigid:bG02eX0lBDOMNFXnCZFNtjMb/YU false sufficient binding region:1-220 sufficient binding region:529-868 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61006 - intact:EBI-3989087|uniprotkb:Q61005|uniprotkb:Q61987|uniprotkb:Q61988|ensembl:ENSMUSP00000081625 - psi-mi:musk_mouse(display_long)|uniprotkb:Musk(gene name)|psi-mi:Musk(display_short)|uniprotkb:Nsk2(gene name synonym)|uniprotkb:Muscle-specific tyrosine-protein kinase receptor(gene name synonym) - psi-mi:"MI:0424"(protein kinase assay) Bergamin et al. (2010) pubmed:20603078 taxid:10090(mouse)|taxid:10090(Mus musculus) - psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-4304848 - - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0898"(putative self) - psi-mi:"MI:0326"(protein) - refseq:NP_001032205.1|refseq:NP_001032206.1|refseq:NP_001032207.1|refseq:NP_035074.2|ensembl:ENSMUSG00000057280(gene)|ensembl:ENSMUST00000084578(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007613"(memory)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:2000541"(positive regulation of protein geranylgeranylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020067|interpro:IPR020635|interpro:IPR036179|interpro:IPR036790|rcsb pdb:3ML4|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation) - - - - figure legend:fig 3|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/10 2014/10/16 rogid:KN1YzYVoSsqXex4SJYxTghIOSx810090 - intact-crc:8593B203AAB6CA6C false - - - - psi-mi:"MI:0396"(predetermined participant) -