#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P2D1 uniprotkb:Q9HCK8 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENSP00000495240 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym) psi-mi:"MI:0018"(two hybrid) Batsukh et al. (2010) pubmed:20453063|imex:IM-17170 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4406092|imex:IM-17170-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F ensembl:ENST00000430710|ensembl:ENSP00000406288|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENST00000645929|ensembl:ENSP00000494402|ensembl:ENSP00000495240|refseq:NP_001164100.1|refseq:NP_065971.2|go:"GO:0035064"(methylated histone binding)|go:"GO:0035176"(social behavior)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048565"(digestive tract development)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070615"|ensembl:ENSG00000100888(gene)|ensembl:ENST00000557364(transcript)|ensembl:ENST00000643469(transcript)|ensembl:ENST00000646647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|go:"GO:0071339"(MLL1 complex)|dip:DIP-38021N - - - figure legend:No figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/09/20 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 rogid:QwADLvHNwK00OAboBtAkqaICd489606 intact-crc:2A8481F6BB8915C9|rigid:lAO4rY9u9hpA/EcyjizBojjShDM false sufficient binding region:1591-2181 sufficient binding region:2068-2370 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P2D1 uniprotkb:Q9HCK8 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENSP00000495240 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym) psi-mi:"MI:0018"(two hybrid) Batsukh et al. (2010) pubmed:20453063|imex:IM-17170 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4406557|imex:IM-17170-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F ensembl:ENST00000430710|ensembl:ENSP00000406288|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENST00000645929|ensembl:ENSP00000494402|ensembl:ENSP00000495240|refseq:NP_001164100.1|refseq:NP_065971.2|go:"GO:0035064"(methylated histone binding)|go:"GO:0035176"(social behavior)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048565"(digestive tract development)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070615"|ensembl:ENSG00000100888(gene)|ensembl:ENST00000557364(transcript)|ensembl:ENST00000643469(transcript)|ensembl:ENST00000646647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|go:"GO:0071339"(MLL1 complex)|dip:DIP-38021N - - - figure legend:Figures 1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/09/20 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 rogid:QwADLvHNwK00OAboBtAkqaICd489606 intact-crc:5FAA81AA9BC62CE2|rigid:lAO4rY9u9hpA/EcyjizBojjShDM false mutation disrupting interaction:2096-2096|mutation disrupting interaction:2108-2108|necessary binding region:1950-2172|mutation disrupting interaction:2091-2091|sufficient binding region:1593-2178 necessary binding region:2068-2262 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P2D1 uniprotkb:Q9HCK8-2 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-4410319|ensembl:ENSP00000406288|ensembl:ENSP00000494402 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q9hck8-2(display_long)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Batsukh et al. (2010) pubmed:20453063|imex:IM-17170 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4406286|imex:IM-17170-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F intact:EBI-1169146(isoform-parent)|ensembl:ENSG00000100888(gene)|ensembl:ENST00000430710(transcript)|ensembl:ENST00000645929(transcript)|uniprotkb:Q9HCK8-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/09/20 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 rogid:X8AJmfiLrD3PFMR0CxCgwnfqHo49606 intact-crc:4C3CDC67639EA52A|rigid:sHXoapw5UfnpYAlazBQUnvmeiVU false sufficient binding region:1596-2178|enhanced green fluorescent protein tag:?-? sufficient binding region:1789-2302|enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9P2D1 uniprotkb:Q9HCK8-2 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-4410319|ensembl:ENSP00000406288|ensembl:ENSP00000494402 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q9hck8-2(display_long)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Batsukh et al. (2010) pubmed:20453063|imex:IM-17170 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4406417|imex:IM-17170-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F intact:EBI-1169146(isoform-parent)|ensembl:ENSG00000100888(gene)|ensembl:ENST00000430710(transcript)|ensembl:ENST00000645929(transcript)|uniprotkb:Q9HCK8-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Figure 4 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/09/20 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 rogid:X8AJmfiLrD3PFMR0CxCgwnfqHo49606 intact-crc:BE2F3D433A072164|rigid:sHXoapw5UfnpYAlazBQUnvmeiVU false sufficient binding region:1593-2178|ha tag:?-? myc tag:n-n|sufficient binding region:1789-2302 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P2D1 uniprotkb:Q9HCK8-2 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-4410319|ensembl:ENSP00000406288|ensembl:ENSP00000494402 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q9hck8-2(display_long)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Batsukh et al. (2010) pubmed:20453063|imex:IM-17170 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4406370|imex:IM-17170-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F intact:EBI-1169146(isoform-parent)|ensembl:ENSG00000100888(gene)|ensembl:ENST00000430710(transcript)|ensembl:ENST00000645929(transcript)|uniprotkb:Q9HCK8-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/09/20 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 rogid:X8AJmfiLrD3PFMR0CxCgwnfqHo49606 intact-crc:5CCF06E8F123811E|rigid:sHXoapw5UfnpYAlazBQUnvmeiVU false ha tag:?-?|sufficient binding region:1593-2178 myc tag:n-n|sufficient binding region:1789-2302 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)