#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35587	uniprotkb:P13987	intact:EBI-4405327	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	-	-	-	figure legend:3a and 6b|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	intact-crc:91EAF74CCA815E8C|rigid:W+lTre7PX86LtozSqbzB5egqJco	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P13987	uniprotkb:Q15363	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405578	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	go:"GO:0045121"(membrane raft)	-	-	figure legend:6c|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:996DCEAB898FE971|rigid:Ql9D4kKLEZYlbRNMQWJQDnPDOHk	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15363	uniprotkb:O35587	intact:EBI-998485|ensembl:ENSP00000262225	intact:EBI-4405327	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	-	-	-	figure legend:S4a|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	intact-crc:015978BD9D7DE591|rigid:n8XZaSlWVqARBDqU+RB7YoUdTN4	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O35587	uniprotkb:P13987	intact:EBI-4405327	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	-	-	-	figure legend:3b|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	intact-crc:7835DC7A9A3445E4|rigid:W+lTre7PX86LtozSqbzB5egqJco	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35587	uniprotkb:O95487	intact:EBI-4405327	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1	-	-	-	figure legend:5i|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	intact-crc:599E83458182827E|rigid:yaOkj1VUUHGyp7baOI//xrtdUVU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94855	uniprotkb:O35587	intact:EBI-748817|intact:EBI-1212263|uniprotkb:Q8IYI7|ensembl:ENSP00000280551	intact:EBI-4405327	psi-mi:sc24d_human(display_long)|uniprotkb:KIAA0755(gene name synonym)|uniprotkb:SEC24D(gene name)|psi-mi:SEC24D(display_short)|uniprotkb:SEC24-related protein D(gene name synonym)	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304995.1|refseq:NP_055637.2|refseq:XP_005263436.1|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:O94855|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|ensembl:ENSG00000150961(gene)|ensembl:ENST00000280551(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	-	-	-	figure legend:5i|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:CuxIZAR5xQP4Kc0ucDYGZ+siB8w9606	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	intact-crc:0097D1406728EF6B|rigid:pxvZv+cbRauZHbWH4f5jjfdQl9E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53992	uniprotkb:O35587	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	intact:EBI-4405327	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	-	-	-	figure legend:5i|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	intact-crc:112694245D47087A|rigid:XzymKOwBGuWd6xLl23fkhus0tBE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95486	uniprotkb:Q15363	intact:EBI-749911|uniprotkb:A8MVW3|uniprotkb:Q96GP7|uniprotkb:Q8WUV2|ensembl:ENSP00000381823	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:sc24a_human(display_long)|uniprotkb:SEC24-related protein A(gene name synonym)|uniprotkb:SEC24A(gene name)|psi-mi:SEC24A(display_short)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068817.1|refseq:NP_001239160.1|ensembl:ENSG00000113615(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENST00000398844(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	-	-	-	figure legend:5j|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:aaPntYTkPDon1zULatrlQ3JzDAE9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:52623FBFAD86B277|rigid:9D3Xr4nvtDMdTqvEA3fUb7i5OEw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15363	uniprotkb:O95487	intact:EBI-998485|ensembl:ENSP00000262225	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1	-	-	-	figure legend:5j|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	intact-crc:52372EBFAD18C277|rigid:28GkCpQ9sRp4gCsgqw9Zc8jobbc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53992	uniprotkb:Q15363	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	-	-	-	figure legend:5j|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:100E3C398F6374FF|rigid:AH41XVpi1TsrOKxqiQ3K8sxIUqs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15363	uniprotkb:O94855	intact:EBI-998485|ensembl:ENSP00000262225	intact:EBI-748817|intact:EBI-1212263|uniprotkb:Q8IYI7|ensembl:ENSP00000280551	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:sc24d_human(display_long)|uniprotkb:KIAA0755(gene name synonym)|uniprotkb:SEC24D(gene name)|psi-mi:SEC24D(display_short)|uniprotkb:SEC24-related protein D(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	refseq:NP_001304995.1|refseq:NP_055637.2|refseq:XP_005263436.1|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:O94855|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|ensembl:ENSG00000150961(gene)|ensembl:ENST00000280551(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175	-	-	-	figure legend:5j|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rogid:CuxIZAR5xQP4Kc0ucDYGZ+siB8w9606	intact-crc:F5FFA69E353330CD|rigid:Okgt9H0zwP+C9s2AhstmF9W197o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15363	uniprotkb:O35587	intact:EBI-998485|ensembl:ENSP00000262225	intact:EBI-4405327	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	-	-	-	figure legend:S4a|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	intact-crc:90F23BF9CE78BA66|rigid:n8XZaSlWVqARBDqU+RB7YoUdTN4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15363	uniprotkb:P49755	intact:EBI-998485|ensembl:ENSP00000262225	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	-	-	-	figure legend:S4b|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	intact-crc:4151F89C016041B8|rigid:xMcvrZZrpmNSic5fXTZWDE6Xau8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35587	uniprotkb:P13987	intact:EBI-4405327	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	-	-	-	figure legend:3e|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	intact-crc:DAE84598CB847E0E|rigid:W+lTre7PX86LtozSqbzB5egqJco	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P13987	uniprotkb:Q15363	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	-	-	-	figure legend:3f and 6e|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:0EE2314EEF176E03|rigid:Ql9D4kKLEZYlbRNMQWJQDnPDOHk	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P13987	uniprotkb:O35587	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	intact:EBI-4405327	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	-	-	-	figure legend:3e|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	intact-crc:CD4795DB239AC8C7|rigid:W+lTre7PX86LtozSqbzB5egqJco	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P13987	uniprotkb:Q15363	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	-	-	-	figure legend:3f|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:182CE98F823A98CF|rigid:Ql9D4kKLEZYlbRNMQWJQDnPDOHk	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03135	uniprotkb:P13987	intact:EBI-603614|ensembl:ENSP00000339191|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405571	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070836"(caveola assembly)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|interpro:IPR018361|mint:Q03135|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|reactome:R-HSA-163560|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-9013423|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENST00000341049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000105974(gene)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0006874"(cellular calcium ion homeostasis)|refseq:NP_001744.2|dip:DIP-5960N	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	go:"GO:0045121"(membrane raft)	-	-	figure legend:6a and 7a|comment:Disrupted by cholesterol depletion|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	intact-crc:02492E2CF3944A69|rigid:dUcPxA/g4VbPZKJHUpE/xTNbKjs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03135	uniprotkb:Q15363	intact:EBI-603614|ensembl:ENSP00000339191|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405571	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070836"(caveola assembly)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|interpro:IPR018361|mint:Q03135|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|reactome:R-HSA-163560|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-9013423|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENST00000341049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000105974(gene)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0006874"(cellular calcium ion homeostasis)|refseq:NP_001744.2|dip:DIP-5960N	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	go:"GO:0045121"(membrane raft)	-	-	figure legend:6a and 7a|comment:Disrupted by cholesterol depletion|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:02492E2CF3944A69|rigid:dUcPxA/g4VbPZKJHUpE/xTNbKjs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03135	uniprotkb:P49755	intact:EBI-603614|ensembl:ENSP00000339191|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405571	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070836"(caveola assembly)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|interpro:IPR018361|mint:Q03135|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|reactome:R-HSA-163560|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-9013423|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENST00000341049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000105974(gene)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0006874"(cellular calcium ion homeostasis)|refseq:NP_001744.2|dip:DIP-5960N	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	go:"GO:0045121"(membrane raft)	-	-	figure legend:6a and 7a|comment:Disrupted by cholesterol depletion|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	intact-crc:02492E2CF3944A69|rigid:dUcPxA/g4VbPZKJHUpE/xTNbKjs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P13987	uniprotkb:Q15363	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405583	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	-	-	-	figure legend:6d|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	intact-crc:A4FAA6800DD88B57|rigid:TyGp+dR+OXHj/sPkU3WfCPfKWzk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P13987	uniprotkb:O35587	intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17	intact:EBI-4405327	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:tmeda_mesau(display_long)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Integral membrane protein p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Bonnon et al. (2010)	pubmed:20427317	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4405583	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript)	interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|refseq:NP_001268617.1|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)	-	-	-	figure legend:6d|curation depth:mimix curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/09/16	2014/10/16	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:1EDPYu7UhaFxs/Trg2iH59qnmwo10036	intact-crc:A4FAA6800DD88B57|rigid:TyGp+dR+OXHj/sPkU3WfCPfKWzk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)