#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P63331 uniprotkb:P47942 intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353 intact:EBI-917570|intact:EBI-6096016|ensembl:ENSRNOP00000012996 psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short) psi-mi:dpyl2_rat(display_long)|uniprotkb:Turned on after division 64 kDa protein(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhu et al. (2010) pubmed:20220019|mint:MINT-8288819|doi:10.1523/JNEUROSCI.5174-09.2010 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7842863|mint:MINT-8291837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8291839(identity) rgd:2517|refseq:NP_001099187.1|ensembl:ENSRNOG00000009625(gene)|ensembl:ENSRNOT00000012996(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:P47942|reactome:R-RNO-399956|reactome:R-RNO-437239|mint:MINT-8291840(identity) - function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint - comment:homomint|comment:mint|figure legend:f6a f6c|partial coverage:partial coverage taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2011/11/14 2014/10/16 rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116 rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010116 intact-crc:9BDF5A5595670B9A|rigid:pmyWnlYPZWMQtwvTIxJQ/XQ8MMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63331 uniprotkb:P47942 intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353 intact:EBI-917570|intact:EBI-6096016|ensembl:ENSRNOP00000012996 psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short) psi-mi:dpyl2_rat(display_long)|uniprotkb:Turned on after division 64 kDa protein(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhu et al. (2010) pubmed:20220019|mint:MINT-8288819|doi:10.1523/JNEUROSCI.5174-09.2010 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7842872|mint:MINT-8291844 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8291846(identity) rgd:2517|refseq:NP_001099187.1|ensembl:ENSRNOG00000009625(gene)|ensembl:ENSRNOT00000012996(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:P47942|reactome:R-RNO-399956|reactome:R-RNO-437239|mint:MINT-8291847(identity) - function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint - comment:homomint|comment:mint|figure legend:f6b f6d|partial coverage:partial coverage taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2011/11/14 2014/10/16 rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116 rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010116 intact-crc:AD18B902E7BDF13F|rigid:pmyWnlYPZWMQtwvTIxJQ/XQ8MMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)