#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H211 uniprotkb:Q14566 intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019 intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156 psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short) psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym) psi-mi:"MI:0096"(pull down) Wei et al. (2010) pubmed:20202939 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3509735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N - - - figure legend:Fig. 1A|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/10 2014/10/16 rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606 rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606 intact-crc:5228B1CC32C1097A|rigid:Rhl4f0m9HXyM8K446QVdnw95BuY false binding-associated region:410-445 binding-associated region:708-721 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9H211 uniprotkb:Q14566 intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019 intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156 psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short) psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym) psi-mi:"MI:0096"(pull down) Wei et al. (2010) pubmed:20202939 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3509775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N - - - figure legend:2e|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/10 2014/10/16 rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606 rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606 intact-crc:B97051B4D55C6235|rigid:Rhl4f0m9HXyM8K446QVdnw95BuY false - binding-associated region:708-821 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14566 uniprotkb:Q9H211 intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156 intact:EBI-456953|uniprotkb:Q86XX9|uniprotkb:Q96CJ5|uniprotkb:Q96GK5|uniprotkb:Q96H67|uniprotkb:Q96HE6|uniprotkb:Q9BWM0|ensembl:ENSP00000301019 psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym) psi-mi:cdt1_human(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:CDT1(gene name)|psi-mi:CDT1(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Wei et al. (2010) pubmed:20202939 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3895508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N refseq:NP_112190.2|dip:DIP-31089N|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|mint:Q9H211|rcsb pdb:2LE8|rcsb pdb:2WVR|rcsb pdb:6QCG|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69205|ensembl:ENSG00000167513(gene)|ensembl:ENST00000301019(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) - - - figure legend:2|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/10 2014/10/16 rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606 rogid:bI5rgPGvSzq78lB8NlXnrPZygNY9606 intact-crc:CEC0999585BBE827|rigid:Rhl4f0m9HXyM8K446QVdnw95BuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)