#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P16104	uniprotkb:O15297	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	intact:EBI-1551512|uniprotkb:Q53XP4|uniprotkb:Q6P991|uniprotkb:Q8IVR6|ensembl:ENSP00000306682	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:ppm1d_human(display_long)|uniprotkb:Protein phosphatase 2C isoform delta(gene name synonym)|uniprotkb:p53-induced protein phosphatase 1(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 delta(gene name synonym)|uniprotkb:PPM1D(gene name)|psi-mi:PPM1D(display_short)|uniprotkb:WIP1(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Moon et al. (2010)	pubmed:20118229|mint:MINT-8288827|doi:10.1074/jbc.M109.071696	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7784653|mint:MINT-8291572	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|mint:MINT-8291574(identity)	refseq:NP_003611.1|dip:DIP-38281N|ensembl:ENSG00000170836(gene)|ensembl:ENST00000305921(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009314"(response to radiation)|go:"GO:0009617"(response to bacterium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR036457|reactome:R-HSA-8878166|mint:MINT-8291575(identity)	-	comment:"Resulting Phenotypic qualities (properties)[PATO]: PATO:0002263 (dephosphorylated)"	-	figure legend:f1|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/14	2014/10/16	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	rogid:U+O94qdtYTuxPdSe0pvO76cStf89606	intact-crc:7F8EF41158AFF2E0|rigid:ZdCr/CnCbjYtkXkaud2y522KZTA	false	phosphorylated residue:140-140(MINT-8291582)|binding-associated region:132-143(MINT-8291580)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16104	uniprotkb:O15297	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	intact:EBI-1551512|uniprotkb:Q53XP4|uniprotkb:Q6P991|uniprotkb:Q8IVR6|ensembl:ENSP00000306682	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:ppm1d_human(display_long)|uniprotkb:Protein phosphatase 2C isoform delta(gene name synonym)|uniprotkb:p53-induced protein phosphatase 1(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 delta(gene name synonym)|uniprotkb:PPM1D(gene name)|psi-mi:PPM1D(display_short)|uniprotkb:WIP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Moon et al. (2010)	pubmed:20118229|mint:MINT-8288827|doi:10.1074/jbc.M109.071696	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7784821|mint:MINT-8291635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|mint:MINT-8291638(identity)	refseq:NP_003611.1|dip:DIP-38281N|ensembl:ENSG00000170836(gene)|ensembl:ENST00000305921(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009314"(response to radiation)|go:"GO:0009617"(response to bacterium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR036457|reactome:R-HSA-8878166|mint:MINT-8291637(identity)	-	-	-	figure legend:f2d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:rapid curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/11/14	2014/10/16	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	rogid:U+O94qdtYTuxPdSe0pvO76cStf89606	intact-crc:F6FBD61C3637FBA0|rigid:ZdCr/CnCbjYtkXkaud2y522KZTA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16104	uniprotkb:O15297	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	intact:EBI-1551512|uniprotkb:Q53XP4|uniprotkb:Q6P991|uniprotkb:Q8IVR6|ensembl:ENSP00000306682	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:ppm1d_human(display_long)|uniprotkb:Protein phosphatase 2C isoform delta(gene name synonym)|uniprotkb:p53-induced protein phosphatase 1(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 delta(gene name synonym)|uniprotkb:PPM1D(gene name)|psi-mi:PPM1D(display_short)|uniprotkb:WIP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Moon et al. (2010)	pubmed:20118229|mint:MINT-8288827|doi:10.1074/jbc.M109.071696	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7784858|mint:MINT-8291642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|mint:MINT-8291645(identity)	refseq:NP_003611.1|dip:DIP-38281N|ensembl:ENSG00000170836(gene)|ensembl:ENST00000305921(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009314"(response to radiation)|go:"GO:0009617"(response to bacterium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR036457|reactome:R-HSA-8878166|mint:MINT-8291644(identity)	-	-	-	figure legend:f2d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:rapid curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/11/14	2014/10/16	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	rogid:U+O94qdtYTuxPdSe0pvO76cStf89606	intact-crc:D6E62DA746C44AF8|rigid:ZdCr/CnCbjYtkXkaud2y522KZTA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)