#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:G5EE01	uniprotkb:O61460	intact:EBI-2914422|ensemblmetazoa:T07A9.6.1	intact:EBI-1788319|uniprotkb:Q21477|ensemblmetazoa:M03A1.1b.1	psi-mi:pten_caeel(display_long)|uniprotkb:daf-18(gene name)|psi-mi:daf-18(display_short)|uniprotkb:Abnormal dauer formation protein 18(gene name synonym)|uniprotkb:T07A9.6(orf name)	psi-mi:vab1_caeel(display_long)|uniprotkb:vab-1(gene name)|psi-mi:vab-1(display_short)|uniprotkb:M03A1.1(orf name)|uniprotkb:Tyrosine-protein kinase Eph receptor(gene name synonym)|uniprotkb:Variable abnormal protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Brisbin et al. (2009)	pubmed:19853560|imex:IM-16903	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3861574|imex:IM-16903-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:T07A9.6.1(transcript)|ensemblmetazoa:WBGene00000913(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016314"(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0040024"(dauer larval development)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048870"(cell motility)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061066"(positive regulation of dauer larval development)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1902074"(response to salt)|uniprotkb:O44405(uniprot-removed-ac)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021|interpro:IPR029023|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR014020(C2 tensin-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_499926.1|reactome:R-CEL-8948747|reactome:R-CEL-8948751|wormbase:T07A9.6|interpro:IPR000387(Protein-tyrosine phosphatase)|reactome:R-CEL-1660499|reactome:R-CEL-1855204|reactome:R-CEL-199418|reactome:R-CEL-202424|reactome:R-CEL-5689880	reactome:R-CEL-3928665|refseq:NP_494806.1|refseq:NP_494807.1|wormbase:M03A1.1a|wormbase:M03A1.1b|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|reactome:R-CEL-2682334|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013420|reactome:R-CEL-9013424|interpro:IPR027936|interpro:IPR036116|reactome:R-CEL-3928662|reactome:R-CEL-3928664|reactome:R-CEL-3928663|ensemblmetazoa:M03A1.1b.1(transcript)|ensemblmetazoa:WBGene00006868(gene)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:1902667"(regulation of axon guidance)	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/03/22	2014/10/16	rogid:T6Ef0AJNc4R06NFepNSRAqTlVS86239	rogid:AVK6SPi3UxMXBJpXbCvByzGgJlc6239	intact-crc:E82C675B75F84982|rigid:jkJdDqfMfqS5H90bYz/iytNjeMs	false	necessary binding region:476-803	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O61460	uniprotkb:G5EE01	intact:EBI-1788319|uniprotkb:Q21477|ensemblmetazoa:M03A1.1b.1	intact:EBI-2914422|ensemblmetazoa:T07A9.6.1	psi-mi:vab1_caeel(display_long)|uniprotkb:vab-1(gene name)|psi-mi:vab-1(display_short)|uniprotkb:M03A1.1(orf name)|uniprotkb:Tyrosine-protein kinase Eph receptor(gene name synonym)|uniprotkb:Variable abnormal protein 1(gene name synonym)	psi-mi:pten_caeel(display_long)|uniprotkb:daf-18(gene name)|psi-mi:daf-18(display_short)|uniprotkb:Abnormal dauer formation protein 18(gene name synonym)|uniprotkb:T07A9.6(orf name)	psi-mi:"MI:0096"(pull down)	Brisbin et al. (2009)	pubmed:19853560|imex:IM-16903	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3861920|imex:IM-16903-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-3928665|refseq:NP_494806.1|refseq:NP_494807.1|wormbase:M03A1.1a|wormbase:M03A1.1b|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|reactome:R-CEL-2682334|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013420|reactome:R-CEL-9013424|interpro:IPR027936|interpro:IPR036116|reactome:R-CEL-3928662|reactome:R-CEL-3928664|reactome:R-CEL-3928663|ensemblmetazoa:M03A1.1b.1(transcript)|ensemblmetazoa:WBGene00006868(gene)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:1902667"(regulation of axon guidance)	ensemblmetazoa:T07A9.6.1(transcript)|ensemblmetazoa:WBGene00000913(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016314"(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0040024"(dauer larval development)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048870"(cell motility)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061066"(positive regulation of dauer larval development)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1902074"(response to salt)|uniprotkb:O44405(uniprot-removed-ac)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021|interpro:IPR029023|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR014020(C2 tensin-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_499926.1|reactome:R-CEL-8948747|reactome:R-CEL-8948751|wormbase:T07A9.6|interpro:IPR000387(Protein-tyrosine phosphatase)|reactome:R-CEL-1660499|reactome:R-CEL-1855204|reactome:R-CEL-199418|reactome:R-CEL-202424|reactome:R-CEL-5689880	-	-	-	figure legend:1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:AVK6SPi3UxMXBJpXbCvByzGgJlc6239	rogid:T6Ef0AJNc4R06NFepNSRAqTlVS86239	intact-crc:D7CFF78A03D751B8|rigid:jkJdDqfMfqS5H90bYz/iytNjeMs	false	glutathione s tranferase tag:?-?	maltose binding protein tag:?-?|sufficient binding region:406-835	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:G5EE01	uniprotkb:O61460	intact:EBI-2914422|ensemblmetazoa:T07A9.6.1	intact:EBI-1788319|uniprotkb:Q21477|ensemblmetazoa:M03A1.1b.1	psi-mi:pten_caeel(display_long)|uniprotkb:daf-18(gene name)|psi-mi:daf-18(display_short)|uniprotkb:Abnormal dauer formation protein 18(gene name synonym)|uniprotkb:T07A9.6(orf name)	psi-mi:vab1_caeel(display_long)|uniprotkb:vab-1(gene name)|psi-mi:vab-1(display_short)|uniprotkb:M03A1.1(orf name)|uniprotkb:Tyrosine-protein kinase Eph receptor(gene name synonym)|uniprotkb:Variable abnormal protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brisbin et al. (2009)	pubmed:19853560|imex:IM-16903	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3861964|imex:IM-16903-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:T07A9.6.1(transcript)|ensemblmetazoa:WBGene00000913(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016314"(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0040024"(dauer larval development)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048870"(cell motility)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061066"(positive regulation of dauer larval development)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1902074"(response to salt)|uniprotkb:O44405(uniprot-removed-ac)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021|interpro:IPR029023|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR014020(C2 tensin-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_499926.1|reactome:R-CEL-8948747|reactome:R-CEL-8948751|wormbase:T07A9.6|interpro:IPR000387(Protein-tyrosine phosphatase)|reactome:R-CEL-1660499|reactome:R-CEL-1855204|reactome:R-CEL-199418|reactome:R-CEL-202424|reactome:R-CEL-5689880	reactome:R-CEL-3928665|refseq:NP_494806.1|refseq:NP_494807.1|wormbase:M03A1.1a|wormbase:M03A1.1b|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|reactome:R-CEL-2682334|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013420|reactome:R-CEL-9013424|interpro:IPR027936|interpro:IPR036116|reactome:R-CEL-3928662|reactome:R-CEL-3928664|reactome:R-CEL-3928663|ensemblmetazoa:M03A1.1b.1(transcript)|ensemblmetazoa:WBGene00006868(gene)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:1902667"(regulation of axon guidance)	-	-	-	figure legend:1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/22	2014/10/16	rogid:T6Ef0AJNc4R06NFepNSRAqTlVS86239	rogid:AVK6SPi3UxMXBJpXbCvByzGgJlc6239	intact-crc:D84267D3663BF4A6|rigid:jkJdDqfMfqS5H90bYz/iytNjeMs	false	maltose binding protein tag:?-?|mutation increasing interaction:137-137	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)