#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13224	uniprotkb:Q9UQM7	intact:EBI-2256942|uniprotkb:Q12919|uniprotkb:Q13220|uniprotkb:Q13225|uniprotkb:Q14CU4|uniprotkb:Q9UM56|intact:EBI-28967100|ensembl:ENSP00000477455	intact:EBI-1383687|uniprotkb:Q9UL21|uniprotkb:Q9Y2H4|uniprotkb:Q9Y352|ensembl:ENSP00000261793|ensembl:ENSP00000500642	psi-mi:nmde2_human(display_long)|uniprotkb:GRIN2B(gene name)|psi-mi:GRIN2B(display_short)|uniprotkb:NMDAR2B(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit 3(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)	psi-mi:kcc2a_human(display_long)|uniprotkb:CAMK2A(gene name)|psi-mi:CAMK2A(display_short)|uniprotkb:CAMKA(gene name synonym)|uniprotkb:KIAA0968(gene name synonym)	psi-mi:"MI:0096"(pull down)	Raveendran et al. (2009)	doi:10.1111/j.1471-4159.2009.06108|pubmed:19453375|mint:MINT-8294337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009347|mint:MINT-8296785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000477455|refseq:XP_011518930.1|refseq:XP_011518931.1|refseq:NP_000825.2|dip:DIP-41002N|refseq:XP_016874708.1|ensembl:ENSG00000273079(gene)|ensembl:ENST00000609686(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S11|rcsb pdb:1S2S|rcsb pdb:2IPV|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-3928662|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9022699|reactome:R-HSA-9032500|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|mint:MINT-8296787(identity)	refseq:NP_741960.1|ensembl:ENSG00000070808(gene)|ensembl:ENST00000348628(transcript)|ensembl:ENST00000672479(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q9UQM7|rcsb pdb:2VZ6|rcsb pdb:3SOA|rcsb pdb:5IG3|rcsb pdb:6OF8|rcsb pdb:6VZK|rcsb pdb:6W4O|rcsb pdb:6W4P|rcsb pdb:6X5G|rcsb pdb:6X5Q|rcsb pdb:6X8V|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XF0|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-4086398|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|go:"GO:0016301"(kinase activity)|reactome:R-HSA-6802952|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802955|dip:DIP-39705N|mint:MINT-8296788(identity)	-	-	-	figure legend:F1C|comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:7SvBEWjPBe8TLnX0Jlow6fxaMDw9606	rogid:7uql+9kLfmK9drY5L0oKOH7zPk49606	intact-crc:343720DC3DCD8831|rigid:4VPmsJjP1pCafxYoySNHmEYuZvY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13224	uniprotkb:Q9UQM7	intact:EBI-2256942|uniprotkb:Q12919|uniprotkb:Q13220|uniprotkb:Q13225|uniprotkb:Q14CU4|uniprotkb:Q9UM56|intact:EBI-28967100|ensembl:ENSP00000477455	intact:EBI-1383687|uniprotkb:Q9UL21|uniprotkb:Q9Y2H4|uniprotkb:Q9Y352|ensembl:ENSP00000261793|ensembl:ENSP00000500642	psi-mi:nmde2_human(display_long)|uniprotkb:GRIN2B(gene name)|psi-mi:GRIN2B(display_short)|uniprotkb:NMDAR2B(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit 3(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)	psi-mi:kcc2a_human(display_long)|uniprotkb:CAMK2A(gene name)|psi-mi:CAMK2A(display_short)|uniprotkb:CAMKA(gene name synonym)|uniprotkb:KIAA0968(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Raveendran et al. (2009)	doi:10.1111/j.1471-4159.2009.06108|pubmed:19453375|mint:MINT-8294337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009366|mint:MINT-8296796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000477455|refseq:XP_011518930.1|refseq:XP_011518931.1|refseq:NP_000825.2|dip:DIP-41002N|refseq:XP_016874708.1|ensembl:ENSG00000273079(gene)|ensembl:ENST00000609686(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S11|rcsb pdb:1S2S|rcsb pdb:2IPV|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-3928662|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9022699|reactome:R-HSA-9032500|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|mint:MINT-8296798(identity)	refseq:NP_741960.1|ensembl:ENSG00000070808(gene)|ensembl:ENST00000348628(transcript)|ensembl:ENST00000672479(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q9UQM7|rcsb pdb:2VZ6|rcsb pdb:3SOA|rcsb pdb:5IG3|rcsb pdb:6OF8|rcsb pdb:6VZK|rcsb pdb:6W4O|rcsb pdb:6W4P|rcsb pdb:6X5G|rcsb pdb:6X5Q|rcsb pdb:6X8V|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XF0|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-4086398|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|go:"GO:0016301"(kinase activity)|reactome:R-HSA-6802952|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802955|dip:DIP-39705N|mint:MINT-8296799(identity)	-	-	-	figure legend:F1D|comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:7SvBEWjPBe8TLnX0Jlow6fxaMDw9606	rogid:7uql+9kLfmK9drY5L0oKOH7zPk49606	intact-crc:D03714165258EA0B|rigid:4VPmsJjP1pCafxYoySNHmEYuZvY	false	binding-associated region:?-?(MINT-8296801)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UQM7	uniprotkb:Q13224	intact:EBI-1383687|uniprotkb:Q9UL21|uniprotkb:Q9Y2H4|uniprotkb:Q9Y352|ensembl:ENSP00000261793|ensembl:ENSP00000500642	intact:EBI-2256942|uniprotkb:Q12919|uniprotkb:Q13220|uniprotkb:Q13225|uniprotkb:Q14CU4|uniprotkb:Q9UM56|intact:EBI-28967100|ensembl:ENSP00000477455	psi-mi:kcc2a_human(display_long)|uniprotkb:CAMK2A(gene name)|psi-mi:CAMK2A(display_short)|uniprotkb:CAMKA(gene name synonym)|uniprotkb:KIAA0968(gene name synonym)	psi-mi:nmde2_human(display_long)|uniprotkb:GRIN2B(gene name)|psi-mi:GRIN2B(display_short)|uniprotkb:NMDAR2B(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit 3(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Raveendran et al. (2009)	doi:10.1111/j.1471-4159.2009.06108|pubmed:19453375|mint:MINT-8294337	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009390|mint:MINT-8296809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741960.1|ensembl:ENSG00000070808(gene)|ensembl:ENST00000348628(transcript)|ensembl:ENST00000672479(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q9UQM7|rcsb pdb:2VZ6|rcsb pdb:3SOA|rcsb pdb:5IG3|rcsb pdb:6OF8|rcsb pdb:6VZK|rcsb pdb:6W4O|rcsb pdb:6W4P|rcsb pdb:6X5G|rcsb pdb:6X5Q|rcsb pdb:6X8V|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XF0|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-4086398|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|go:"GO:0016301"(kinase activity)|reactome:R-HSA-6802952|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802955|dip:DIP-39705N|mint:MINT-8296812(identity)	ensembl:ENSP00000477455|refseq:XP_011518930.1|refseq:XP_011518931.1|refseq:NP_000825.2|dip:DIP-41002N|refseq:XP_016874708.1|ensembl:ENSG00000273079(gene)|ensembl:ENST00000609686(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S11|rcsb pdb:1S2S|rcsb pdb:2IPV|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-3928662|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9022699|reactome:R-HSA-9032500|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|mint:MINT-8296811(identity)	-	-	-	figure legend:F2|comment:homomint|comment:mint|partial coverage:partial coverage	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/11/29	2014/10/16	rogid:7uql+9kLfmK9drY5L0oKOH7zPk49606	rogid:7SvBEWjPBe8TLnX0Jlow6fxaMDw9606	intact-crc:94F84C7A5E9E58BF|rigid:4VPmsJjP1pCafxYoySNHmEYuZvY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62139	uniprotkb:Q13224	intact:EBI-2008988|uniprotkb:P08128|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802	intact:EBI-2256942|uniprotkb:Q12919|uniprotkb:Q13220|uniprotkb:Q13225|uniprotkb:Q14CU4|uniprotkb:Q9UM56|intact:EBI-28967100|ensembl:ENSP00000477455	psi-mi:pp1a_rabit(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:nmde2_human(display_long)|uniprotkb:GRIN2B(gene name)|psi-mi:GRIN2B(display_short)|uniprotkb:NMDAR2B(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit 3(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Raveendran et al. (2009)	doi:10.1111/j.1471-4159.2009.06108|pubmed:19453375|mint:MINT-8294337	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009409|mint:MINT-8297082	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_001095176.1|rcsb pdb:1FJM|interpro:IPR031675|interpro:IPR029052|interpro:IPR037979|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901567"(fatty acid derivative binding)|go:"GO:1904886"(beta-catenin destruction complex disassembly)|mint:MINT-8297084(identity)	ensembl:ENSP00000477455|refseq:XP_011518930.1|refseq:XP_011518931.1|refseq:NP_000825.2|dip:DIP-41002N|refseq:XP_016874708.1|ensembl:ENSG00000273079(gene)|ensembl:ENST00000609686(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S11|rcsb pdb:1S2S|rcsb pdb:2IPV|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-3928662|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9022699|reactome:R-HSA-9032500|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|mint:MINT-8297085(identity)	-	-	-	comment:mint|figure legend:F7B|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9986	rogid:7SvBEWjPBe8TLnX0Jlow6fxaMDw9606	intact-crc:69C2A13206FCF522|rigid:dhQIb7QARokOWmfvaX5ZzdpSACU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48452	uniprotkb:Q13224	intact:EBI-7009422|ensembl:ENSBTAP00000021305|uniprotkb:Q309F2|intact:UNK-6038769|uniprotkb:Q08DM4	intact:EBI-2256942|uniprotkb:Q12919|uniprotkb:Q13220|uniprotkb:Q13225|uniprotkb:Q14CU4|uniprotkb:Q9UM56|intact:EBI-28967100|ensembl:ENSP00000477455	psi-mi:pp2ba_bovin(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)	psi-mi:nmde2_human(display_long)|uniprotkb:GRIN2B(gene name)|psi-mi:GRIN2B(display_short)|uniprotkb:NMDAR2B(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit 3(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Raveendran et al. (2009)	doi:10.1111/j.1471-4159.2009.06108|pubmed:19453375|mint:MINT-8294337	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009417|mint:MINT-8297089	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000016005(gene)|ensembl:ENSBTAT00000021305(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030018"(Z disc)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0043197"(dendritic spine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|rcsb pdb:1TCO|rcsb pdb:2F2O|rcsb pdb:2F2P|refseq:NP_777212.1|refseq:XP_005207750.1|mint:MINT-8297091(identity)	ensembl:ENSP00000477455|refseq:XP_011518930.1|refseq:XP_011518931.1|refseq:NP_000825.2|dip:DIP-41002N|refseq:XP_016874708.1|ensembl:ENSG00000273079(gene)|ensembl:ENST00000609686(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S11|rcsb pdb:1S2S|rcsb pdb:2IPV|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-3928662|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9022699|reactome:R-HSA-9032500|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|mint:MINT-8297092(identity)	-	comment:mint|comment:homomint|function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1	-	comment:homomint|comment:mint|figure legend:F7B|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:UG/r5TNASCY5Sl3vfOaPt41R3bY9913	rogid:7SvBEWjPBe8TLnX0Jlow6fxaMDw9606	intact-crc:7FD6C054AC50BF7A|rigid:Eeu9VqrKxmMPFGBKg4fnfhPZByo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62139	uniprotkb:Q13224	intact:EBI-2008988|uniprotkb:P08128|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802	intact:EBI-2256942|uniprotkb:Q12919|uniprotkb:Q13220|uniprotkb:Q13225|uniprotkb:Q14CU4|uniprotkb:Q9UM56|intact:EBI-28967100|ensembl:ENSP00000477455	psi-mi:pp1a_rabit(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:nmde2_human(display_long)|uniprotkb:GRIN2B(gene name)|psi-mi:GRIN2B(display_short)|uniprotkb:NMDAR2B(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit 3(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)	psi-mi:"MI:1088"(phenotype-based detection assay)	Raveendran et al. (2009)	doi:10.1111/j.1471-4159.2009.06108|pubmed:19453375|mint:MINT-8294337	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009495|mint:MINT-8297097	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_001095176.1|rcsb pdb:1FJM|interpro:IPR031675|interpro:IPR029052|interpro:IPR037979|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901567"(fatty acid derivative binding)|go:"GO:1904886"(beta-catenin destruction complex disassembly)|mint:MINT-8297099(identity)	ensembl:ENSP00000477455|refseq:XP_011518930.1|refseq:XP_011518931.1|refseq:NP_000825.2|dip:DIP-41002N|refseq:XP_016874708.1|ensembl:ENSG00000273079(gene)|ensembl:ENST00000609686(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S11|rcsb pdb:1S2S|rcsb pdb:2IPV|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:6XBP|rcsb pdb:6XBX|rcsb pdb:6XDL|rcsb pdb:6XDU|rcsb pdb:6XOE|rcsb pdb:7KL0|rcsb pdb:7KL1|rcsb pdb:7KL2|rcsb pdb:7KL4|reactome:R-HSA-3928662|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9022699|reactome:R-HSA-9032500|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|mint:MINT-8297100(identity)	-	-	-	figure legend:F7C|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9986	rogid:7SvBEWjPBe8TLnX0Jlow6fxaMDw9606	intact-crc:07F92883F0BB00EC|rigid:dhQIb7QARokOWmfvaX5ZzdpSACU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)