#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q63664 uniprotkb:Q08209 intact:EBI-6991142|ensembl:ENSRNOP00000018057|intact:MINT-8297391|uniprotkb:Q9JM49|uniprotkb:Q9JM50 intact:EBI-352922|uniprotkb:Q8TAW9|uniprotkb:A8K3B7|uniprotkb:B5BUA2|uniprotkb:A1A441|uniprotkb:A8W6Z7|ensembl:ENSP00000378323|uniprotkb:A8W6Z8 psi-mi:kcnj8_rat(display_long)|uniprotkb:Kcnj8(gene name)|psi-mi:Kcnj8(display_short)|uniprotkb:"Inward rectifier K(+) channel Kir6.1"(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 8(gene name synonym)|uniprotkb:uKATP-1(gene name synonym) psi-mi:pp2ba_human(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:CALNA(gene name synonym)|uniprotkb:CNA(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym) psi-mi:"MI:0434"(phosphatase assay) Orie et al. (2009) doi:10.1111/j.1476-5381.2009.00221|pubmed:19422382|mint:MINT-8297345 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0203"(dephosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-6991175|mint:MINT-8297778 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000013463(gene)|ensembl:ENSRNOT00000018057(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0008282"(inward rectifying potassium channel)|go:"GO:0015272"(ATP-activated inward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030016"(myofibril)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0051607"(defense response to virus)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296025|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003278(Potassium channel, inwardly rectifying, Kir6.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|refseq:NP_058795.3|rgd:2960|mint:MINT-8297780(identity) go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:Q08209|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2JOG|rcsb pdb:2JZI|rcsb pdb:2P6B|rcsb pdb:2R28|rcsb pdb:2W73|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4Q5U|rcsb pdb:5C1V|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:6UUQ|reactome:R-HSA-180024|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|reactome:R-HSA-2025928|refseq:NP_000935.1|refseq:NP_001124163.1|refseq:NP_001124164.1|go:"GO:0043197"(dendritic spine)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000138814(gene)|ensembl:ENST00000394854(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042383"(sarcolemma)|dip:DIP-6095N|mint:MINT-8297781(identity) - comment:mint - figure legend:F6|comment:mint|partial coverage:partial coverage taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/02 2014/10/16 rogid:xhWqFMk/3Dh5rwvrRtpNSQy/6fU10116 rogid:kYtl+Yk39rbcDp5vIjH8WLsZysU9606 intact-crc:701167DA22759C63|rigid:Ka9z/SHs17kOQ01pZfcwH6zY96M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)