#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5T4F4 uniprotkb:Q9P0L0 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:table 1|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 intact-crc:381851CBA453B85E|rigid:uBYfDuynbuwoS59WjrZRink8hbo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q5T4F4 uniprotkb:O95292 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:table 1|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 intact-crc:381851CBA453B85E|rigid:uBYfDuynbuwoS59WjrZRink8hbo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q5T4F4 uniprotkb:P50991 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:table 1|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:381851CBA453B85E|rigid:uBYfDuynbuwoS59WjrZRink8hbo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q5T4F4 uniprotkb:P48643 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:table 1|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:381851CBA453B85E|rigid:uBYfDuynbuwoS59WjrZRink8hbo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q5T4F4 uniprotkb:P49368 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:table 1|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:381851CBA453B85E|rigid:uBYfDuynbuwoS59WjrZRink8hbo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q5T4F4 uniprotkb:Q9P0L0 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:1A and 3B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 intact-crc:8E3F42450CCA7A89|rigid:BTxgIgWRqYoWWLKJKmcMOQkdEF4 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T4F4 uniprotkb:O95292 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:1A|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 intact-crc:4489228E0B12A3F1|rigid:d5mRA6fw9dhNSoYhQXK/2XXzRuQ false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3TXX3 uniprotkb:Q9WV55 intact:EBI-3899155|uniprotkb:Q8CFP8|ensembl:ENSMUSP00000130684 intact:EBI-645974|uniprotkb:Q9QY77|uniprotkb:Q3TJM1|ensembl:ENSMUSP00000024897 psi-mi:zfy27_mouse(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:Zfyve27(gene name)|psi-mi:Zfyve27(display_short) psi-mi:vapa_mouse(display_long)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)|uniprotkb:Vapa(gene name)|psi-mi:Vapa(display_short)|uniprotkb:Vap33(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158003.1|refseq:NP_796293.2|ensembl:ENSMUSG00000018820(gene)|ensembl:ENSMUST00000169536(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405 refseq:NP_038961.2|ensembl:ENSMUSG00000024091(gene)|ensembl:ENSMUST00000024897(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9WV55|rcsb pdb:2CRI|reactome:R-MMU-1660661|reactome:R-MMU-6798695|reactome:R-MMU-9609523 - - - figure legend:1B|curation depth:mimix curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2011/05/05 2014/10/16 rogid:aG7LuQXglOsEIKKXlz1tQScwMnY10090 rogid:LQV6uN7oD/EpHQvexl/pGkG6bmE10090 intact-crc:15667B42BD8EA164|rigid:rqvRq1eU/qKYfKXnWHhdqnR+TcM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T4F4 uniprotkb:Q9P0L0 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:2B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 intact-crc:5C0DFF560D4C37E0|rigid:BTxgIgWRqYoWWLKJKmcMOQkdEF4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T4F4 uniprotkb:Q9P0L0 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3894254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:3E|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 intact-crc:A5B106F8DE49A004|rigid:BTxgIgWRqYoWWLKJKmcMOQkdEF4 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T4F4 uniprotkb:Q9P0L0 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Saita et al. (2009) pubmed:19289470 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-3894265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:4A|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/05 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 intact-crc:7C305CFC85791DF6|rigid:BTxgIgWRqYoWWLKJKmcMOQkdEF4 false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)